BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0031.0167.p (314 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0360 [QR] COG0500 SAM-dependent methyltransferases Rso Ralsto... 245 8e-65 XF2099 [QR] COG0500 SAM-dependent methyltransferases Xfa Xylella... 159 8e-39 NMB0271 [QR] COG0500 SAM-dependent methyltransferases Nme Neisse... 105 9e-23 BMEI0182 [QR] COG0500 SAM-dependent methyltransferases Bme Bruce... 99 2e-20 AGl1526GM [QR] COG0500 SAM-dependent methyltransferases Atu Agro... 97 4e-20 VC1114 [QR] COG0500 SAM-dependent methyltransferases Vch Vibrio ... 97 5e-20 SMc02445 [QR] COG0500 SAM-dependent methyltransferases Sme Sinor... 93 1e-18 NMA2215 [QR] COG0500 SAM-dependent methyltransferases NmA Neisse... 92 2e-18 CC0831 [QR] COG0500 SAM-dependent methyltransferases Ccr Cauloba... 89 1e-17 PA0503 [QR] COG0500 SAM-dependent methyltransferases Pae Pseudom... 87 6e-17 >RSc0360 [QR] COG0500 SAM-dependent methyltransferases Rso Ralstonia solanacearum Length = 367 Score = 245 bits (626), Expect = 8e-65, Method: Compositional matrix adjust. Identities = 142/294 (48%), Positives = 177/294 (60%), Gaps = 27/294 (9%) Query: 33 ESDFLRREVSTRMQERLALVKIHPREVLDAGCGEGADLPVLQKRYPEAQVVGLDGAYGML 92 E+DFL REV RMQ+RL+ +K+ P LD GCG G L VL+ +YP+AQ+ GLD + ML Sbjct: 79 EADFLLREVGQRMQDRLSYIKLTPARALDLGCGLGQGLAVLRAQYPDAQICGLDWSAAML 138 Query: 93 AVA----AEHQRGAQSAMNRLFGSINKWLGSGPALSGPELACADFARLPLAANALDLVWS 148 A A +H G G + + L P + A ADF LP A + DL+WS Sbjct: 139 ARARQLDPQHSDG---------GWLGRLLKKRPVF---DFAQADFRALPFADASFDLLWS 186 Query: 149 NLALHWHPQPDRVFAEWRRVLRVEGLLMFSCFGPDTLREVRSAFERIDLAPHTLPFVDMH 208 NLALHW P P +F EW RV GLLMFS FGPDTLRE+RSA ID + HTL FVDMH Sbjct: 187 NLALHWDPSPHAIFPEWHRVTAEGGLLMFSLFGPDTLRELRSALAGIDASVHTLRFVDMH 246 Query: 209 DFGDMLVNAGFSTPVMDMETITVTYDTPQRLLEDVRAWGG--NPLETRRRSMMSRDQY-- 264 D GDMLV+ +STPVMDME IT+TY++PQ LL DV GG + R++ Y Sbjct: 247 DIGDMLVHGRWSTPVMDMEQITITYESPQALLADVHLLGGMAGLADGDGRALSGPGLYTP 306 Query: 265 ---QRLWAAFEAMRKPDGKIPLTFEIIYGHAFRPVPKTTAA----GESIIRFDR 311 Q L+ A +A R PDG IPLTFE++YGHA++ P A G ++I DR Sbjct: 307 RWRQHLFDALDAQRNPDGLIPLTFEVVYGHAWKLAPNPRQALDEQGRAMIPVDR 360 >XF2099 [QR] COG0500 SAM-dependent methyltransferases Xfa Xylella fastidiosa 9a5c Length = 295 Score = 159 bits (402), Expect = 8e-39, Method: Compositional matrix adjust. Identities = 102/284 (35%), Positives = 146/284 (51%), Gaps = 24/284 (8%) Query: 16 IDLPLVRRRFAHPQRVAESD-FLRREVSTRMQERLALVKIH-PREVLDAGCGEGADLPVL 73 D +RR F+ R +++ L+ EV R+ E L + PR +LD G G G + Sbjct: 5 FDTSHIRRAFSRAARSYDTNAILQHEVEQRLLESLDYLGDRIPRVILDVGAGTGRASIAM 64 Query: 74 QKRYPEAQVVGLDGAYGMLAVAAEHQRGAQSAMNRLFGSINKWLGSGPALSGPELACADF 133 +KR+P+AQV+ D A ML Q A R + W + C D Sbjct: 65 KKRWPKAQVIAFDQAMPML----------QEARKR-----SHWWKPLAQI------CGDA 103 Query: 134 ARLPLAANALDLVWSNLALHWHPQPDRVFAEWRRVLRVEGLLMFSCFGPDTLREVRSAFE 193 LP+A ++D+++SNL L W VFA +R+ LR GLL+ S FGPDTL E+R AF Sbjct: 104 RTLPVADASVDVIFSNLCLQWIEDLPTVFAGFRQALRPGGLLLCSLFGPDTLIELREAFA 163 Query: 194 RIDLAPHTLPFVDMHDFGDMLVNAGFSTPVMDMETITVTYDTPQRLLEDVRAWGG-NPLE 252 + D PH PF M GD LV A F PV+D + T+TYD L+ +RA G N L+ Sbjct: 164 QADAVPHISPFPSMPQCGDALVLAHFQNPVLDRDLFTLTYDNLSALMRSLRAIGATNALQ 223 Query: 253 TRRRSMMSRDQYQRLWAAFEAMRKPDGKIPLTFEIIYGHAFRPV 296 RR ++ R ++ A+E +R D K+P ++E+IY A+ P Sbjct: 224 ERRTTLTGRGRFAATATAYETLRNADNKLPSSWEVIYACAWAPT 267 >NMB0271 [QR] COG0500 SAM-dependent methyltransferases Nme Neisseria meningitidis MC58 Length = 262 Score = 105 bits (263), Expect = 9e-23, Method: Compositional matrix adjust. Identities = 81/273 (29%), Positives = 121/273 (44%), Gaps = 24/273 (8%) Query: 37 LRREVSTRMQERLALVKIHPREVLDAGCGEGADLPVLQKRYPEAQVVGLDGAYGMLAVAA 96 + R ++ +RL LV+ P+ +L AG +L KRYP+A D LA AA Sbjct: 10 VHRHLAEHTDQRLTLVRNAPKHILLAGADADISRSLLAKRYPQAVFEEYDSRADFLAAAA 69 Query: 97 EHQRGAQSAMNRLFGSINKWLGSGPALSGPELACADFARLPLAANALDLVWSNLALHWHP 156 ++G R G P PE ACAD ++WSNL L Sbjct: 70 AARKGG--FWQRFTGKGVVQHCQSPIAPLPE-ACAD------------MLWSNLGLLAAE 114 Query: 157 QPDRVFAEWRRVLRVEGLLMFSCFGPDTLREVRSAFERIDLAPHTLPFVDMHDFGDMLVN 216 Q V W R L+ +GLL F+CFG DTL E++ + + + F DMHD GDML Sbjct: 115 QILPVLHNWARALKTDGLLFFTCFGRDTLAELKCRLKENGIESRSALFPDMHDLGDMLAE 174 Query: 217 AGFSTPVMDMETITVTYDTPQRLLEDVRAWGGNPLETRRRSMMSRDQYQRLWAAFEAMRK 276 GF PV D + + Y + D+ G R+M D+ + + + Sbjct: 175 NGFYDPVTDTAKLVLDYKKAETFWADMDTLG------VWRAMAWNDENAAR-SCVGTIFE 227 Query: 277 PDGKIPLTFEIIYGHAFRPVPKTTAAGESIIRF 309 +G + +T E +YGHA + + GE++++F Sbjct: 228 REGGLGITLETVYGHAVKKL--MLPQGENVVQF 258 >BMEI0182 [QR] COG0500 SAM-dependent methyltransferases Bme Brucella melitensis Length = 297 Score = 98.6 bits (244), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 91/287 (31%), Positives = 132/287 (45%), Gaps = 38/287 (13%) Query: 17 DLPLVRRRFAHPQRVAESDFLRREVSTRMQERLALVKIHPREVLDAGCGEGADLPVLQKR 76 DL L RR A + +DFL R V+ +++RL V ++R Sbjct: 14 DLMLAFRRRAFQRAEPGADFLLRRVADDLEKRLGAV---------------------ERR 52 Query: 77 YPEAQVVGLDGAYGMLAVAAEHQRGAQSAMNRLFGSINKWLGSGPALSGPELACADFARL 136 +P A V L G G A AA Q G + R+ G PA+ G E A L Sbjct: 53 FPVA--VDLAGHTGA-AAAAIAQTGKADYVLRIERDTEFLQGPFPAIVGDEEA------L 103 Query: 137 PLAANALDLVWSNLALHWHPQPDRVFAEWRRVLRVEGLLMFSCFGPDTLREVRSAFERID 196 PL + DL+ S +ALH + R L+ +GL + + G TL E+R + + + Sbjct: 104 PLKPGSADLIVSLMALHATNDTPGAMVQIARALKPDGLFLAALSGSGTLGELRESLLQAE 163 Query: 197 L------APHTLPFVDMHDFGDMLVNAGFSTPVMDMETITVTYDTPQRLLEDVRAWG-GN 249 + +P +PF D+ D G +L AGF+ PV D+E ITV YD+ L+ D+RA G N Sbjct: 164 IELTGGASPRVMPFADVRDVGSLLQRAGFALPVTDVENITVRYDSLFNLMADLRAMGMQN 223 Query: 250 PLETRRRSMMSRDQYQRLWAAF-EAMRKPDGKIPLTFEIIYGHAFRP 295 L R R +S+ + R + E PDG+I TF II+ + P Sbjct: 224 ILHGRSRKPVSKRLFLRAAEIYAERFSDPDGRIRATFSIIWLSGWAP 270 >AGl1526GM [QR] COG0500 SAM-dependent methyltransferases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 263 Score = 97.4 bits (241), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 63/174 (36%), Positives = 88/174 (50%), Gaps = 8/174 (4%) Query: 130 CADFARLPLAANALDLVWSNLALHWHPQPDRVFAEWRRVLRVEGLLMFSCFGPDTLREVR 189 A LPLA + +L+ S LALH + RR L+ +GL + + G TL E+R Sbjct: 61 TASMEHLPLAEASANLIVSPLALHLTNDTPGALIQIRRALKPDGLFLGAIPGSGTLHELR 120 Query: 190 SAFERIDL------APHTLPFVDMHDFGDMLVNAGFSTPVMDMETITVTYDTPQRLLEDV 243 + +P +PF D+ D G +L AGF+ PV D ET TV YD+ L+ D+ Sbjct: 121 DVLLTAEAELTGGASPRVIPFADVRDVGALLQRAGFALPVTDAETYTVRYDSIFPLMRDL 180 Query: 244 RAWG-GNPLETRRRSMMSRDQYQRLWAAF-EAMRKPDGKIPLTFEIIYGHAFRP 295 RA G NPL +R R ++R + R + E PDG+I TF IIY + P Sbjct: 181 RAMGMANPLASRSRKPLNRAFFLRAAELYAERYSDPDGRIRATFSIIYVSGWAP 234 >VC1114 [QR] COG0500 SAM-dependent methyltransferases Vch Vibrio cholerae Length = 312 Score = 97.1 bits (240), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 70/254 (27%), Positives = 115/254 (45%), Gaps = 25/254 (9%) Query: 37 LRREVSTRMQERLALVKIHPREVLDAGCGEGADLPVLQKRYPEAQVVGLDGAYGMLAVAA 96 +R+V R+ +++ + VLD GCG G +L++R AQVV D ++ ML A Sbjct: 80 FQRDVGLRLLQKMPSC-LKGLRVLDLGCGTGYFSALLRER--GAQVVCADISHAMLEQAK 136 Query: 97 EHQRGAQSAMNRLFGSINKWLGSGPALSGPELACADFARLPLAANALDLVWSNLALHWHP 156 QR M+ AD +LP A+ D+V+S+LAL W Sbjct: 137 --QRCGDEGMSYQL--------------------ADAEQLPFASACFDMVFSSLALQWCE 174 Query: 157 QPDRVFAEWRRVLRVEGLLMFSCFGPDTLREVRSAFERIDLAPHTLPFVDMHDFGDMLVN 216 +E RRVL+ G S +L E+ A+ +D H F+ ++ L Sbjct: 175 DLSLPLSEIRRVLKPHGQAFLSTLLDGSLFELEQAWRSVDHHRHINQFISINQVKIALAQ 234 Query: 217 AGFSTPVMDMETITVTYDTPQRLLEDVRAWGGNPLETRRRSMMSRDQYQRLWAAFEAMRK 276 AG S +D+ ITV Y+ L+ D++ G N + R ++SR ++ A+++ R Sbjct: 235 AGCSQHHLDLAAITVWYEAAFMLMRDLKGIGANHVSGRSTGLISRRTLAKVELAYQSFRN 294 Query: 277 PDGKIPLTFEIIYG 290 G +P T+++ G Sbjct: 295 QQGLVPATYQVCLG 308 >SMc02445 [QR] COG0500 SAM-dependent methyltransferases Sme Sinorhizobium meliloti Length = 298 Score = 92.8 bits (229), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 64/167 (38%), Positives = 90/167 (53%), Gaps = 8/167 (4%) Query: 131 ADFARLPLAANALDLVWSNLALHWHPQPDRVFAEWRRVLRVEGLLMFSCFGPDTLREVRS 190 A R+P +L+L+ S L+LH VF + RRVL+ +GL + + G TL+E+R Sbjct: 92 APLERIPAEPASLNLLVSPLSLHLTNDTPGVFIQARRVLKPDGLFLAAIPGSGTLQELRE 151 Query: 191 AFERIDL------APHTLPFVDMHDFGDMLVNAGFSTPVMDMETITVTYDTPQRLLEDVR 244 A + +P +PF D+ D G +L AGF+ PV D ET TV YD+ L+ D+R Sbjct: 152 ALLAAEAELTGGASPRVIPFADVRDMGALLQRAGFALPVADTETYTVRYDSLFGLIRDLR 211 Query: 245 AWG-GNPLETRRRSMMSRDQYQRLWAAF-EAMRKPDGKIPLTFEIIY 289 A G NPL +R R M R + R + + PDG+I TF IIY Sbjct: 212 AMGMTNPLASRNRKPMPRRFFLRAAEIYAQRFSDPDGRIRATFSIIY 258 >NMA2215 [QR] COG0500 SAM-dependent methyltransferases NmA Neisseria meningitidis Z2491 Length = 198 Score = 92.0 bits (227), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 53/173 (30%), Positives = 83/173 (47%), Gaps = 9/173 (5%) Query: 137 PLAANALDLVWSNLALHWHPQPDRVFAEWRRVLRVEGLLMFSCFGPDTLREVRSAFERID 196 PL D++WSNL L V W R L+ +GLL F+CFG DTL E++ + Sbjct: 31 PLPEACADMLWSNLGLLAAESIVPVLQNWARALKTDGLLFFTCFGRDTLAELKCRLKENG 90 Query: 197 LAPHTLPFVDMHDFGDMLVNAGFSTPVMDMETITVTYDTPQRLLEDVRAWGGNPLETRRR 256 + ++ F DMHD GDML GF PV D + + Y + D+ G R Sbjct: 91 IESRSVMFPDMHDLGDMLAENGFYDPVTDTAKLVLDYKKAETFWADMDTLG------IWR 144 Query: 257 SMMSRDQYQRLWAAFEAMRKPDGKIPLTFEIIYGHAFRPVPKTTAAGESIIRF 309 +M D+ + + + +G + +T E +YGHA + + GE++++F Sbjct: 145 AMAWNDENAAR-SCVGTIFEREGGLGITLETVYGHAVKKL--MLPQGENVVQF 194 >CC0831 [QR] COG0500 SAM-dependent methyltransferases Ccr Caulobacter vibrioides Length = 303 Score = 88.6 bits (218), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 63/180 (35%), Positives = 88/180 (48%), Gaps = 10/180 (5%) Query: 119 SGPALSGPELA--CADFARLPLAANALDLVWSNLALHWHPQPDRVFAEWRRVLRVEGLLM 176 SG L+G E AD RLP LDL+ S L+LHW + RR LR +GL + Sbjct: 84 SGRMLAGRETLRLVADEERLPFGDATLDLLVSTLSLHWTNDLVGALIQIRRALRPDGLFV 143 Query: 177 FSCFGPDTLREVRSAF-----ERIDLAPHTL-PFVDMHDFGDMLVNAGFSTPVMDMETIT 230 + FG TL E+R E D A + PF D D +L AGF+ PV D++ + Sbjct: 144 GALFGGATLTELRQCLLAAEAELTDGAAMRVSPFADAIDAAGLLQRAGFALPVADVDRVK 203 Query: 231 VTYDTPQRLLEDVRAWGGNP--LETRRRSMMSRDQYQRLWAAFEAMRKPDGKIPLTFEII 288 V Y P LL D+R G L+ R+ + + ++ + E + DGK+P TFEI+ Sbjct: 204 VRYAHPIALLRDLRKMGETSVLLDRSRKPLTRKVLFRAMELYVERFAEADGKVPATFEIV 263 >PA0503 [QR] COG0500 SAM-dependent methyltransferases Pae Pseudomonas aeruginosa Length = 274 Score = 86.7 bits (213), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 68/236 (28%), Positives = 109/236 (46%), Gaps = 26/236 (11%) Query: 56 PREVLDAGCGEGADLPVLQKRYPEAQVVGLDGAYGMLAVAAEHQRGAQSAMNRLFGSINK 115 PR +D GCG G L++R+ A+ + +D A GML A R G + Sbjct: 58 PRRWVDLGCGTGYFSRALERRFGAAEGLAVDIAEGMLRHA------------RARGGASH 105 Query: 116 WLGSGPALSGPELACADFARLPLAANALDLVWSNLALHWHPQPDRVFAEWRRVLRVEGLL 175 ++G D RLPL + DL++S+LA+ W V AE RRVLR G+L Sbjct: 106 FIG------------GDAERLPLRDGSCDLLFSSLAIQWCADLPAVLAEARRVLRPGGVL 153 Query: 176 MFSCFGPDTLREVRSAFERIDLAPHTLPFVDMHDFGDMLVNAGFSTPVMDMETITVTYDT 235 FS TL E+R ++ +D H F D+ +G + E + + Sbjct: 154 AFSSLCVGTLGELRDSWRVVDGFVHVNRFRAFADYLQHAAGSGLLPLTLRHEDRLLHFPD 213 Query: 236 PQRLLEDVRAWGGNPLETRR-RSMMSRDQYQRLWAAFEAMRKPDGKIPLTFEIIYG 290 + L +++A G + L R + R + + L AA+E R+P+G +P T+ +++G Sbjct: 214 LRSLTHELKALGAHNLNPGRPDGLTGRQRIRALVAAYERFRQPEG-LPATYRVVFG 268