BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0031.0141.p (188 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ydbS [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Eco Esc... 207 2e-53 PA1629 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pae P... 183 2e-46 AF0435 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Afu A... 168 7e-42 BMEII1021 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Bm... 167 9e-42 AF0963 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Afu A... 164 1e-40 BMEI1945 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Bme... 163 2e-40 PA3591 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pae P... 160 2e-39 CC0006 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Ccr C... 160 2e-39 BMEII0214 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Bm... 158 8e-39 BH0201 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Bha B... 157 1e-38 >ydbS [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Eco Escherichia coli K12 Length = 255 Score = 207 bits (526), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 107/188 (56%), Positives = 134/188 (71%) Query: 1 MIHKDAIATQLDVRAQYWRAIARFPKPILAAVNGYALGAGCELLMHADIAIAARGAKIGQ 60 M KD AT D R Q W + F KP++AAVNGYALGAGCEL + D+ +A A+ G Sbjct: 68 MAEKDLAATLNDTRPQLWARLQAFNKPLIAAVNGYALGAGCELALLCDVVVAGENARFGL 127 Query: 61 PEINVGTIPGAGGTQRLIRTVGKPLAMKMVLSGEFISADQALQAGLVAEVVDDDATLERT 120 PEI +G +PGAGGTQRLIR+VGK LA KMVLSGE I+A QA QAGLV++V D TLE Sbjct: 128 PEITLGIMPGAGGTQRLIRSVGKSLASKMVLSGESITAQQAQQAGLVSDVFPSDLTLEYA 187 Query: 121 LALAHSIAQKSPLAVRLAKEAMLQSFELGLEAGLLFERKSFSLMAASADRQEGIAAFQEK 180 L LA +A+ SPLA++ AK+A+ QS E+ L+AGL ER+ F+L+AA+ DR EGI+AF +K Sbjct: 188 LQLASKMARHSPLALQAAKQALRQSQEVALQAGLAQERQLFTLLAATEDRHEGISAFLQK 247 Query: 181 RAAVFSGR 188 R F GR Sbjct: 248 RTPDFKGR 255 >PA1629 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pae Pseudomonas aeruginosa Length = 261 Score = 183 bits (465), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 91/173 (52%), Positives = 121/173 (69%) Query: 16 QYWRAIARFPKPILAAVNGYALGAGCELLMHADIAIAARGAKIGQPEINVGTIPGAGGTQ 75 +YW AIAR PKP++AAVNG+ALG GCEL MH D+ +A A+ QPEI VG +PGAGGTQ Sbjct: 89 RYWEAIARCPKPVIAAVNGFALGGGCELAMHCDLIVAGESAQFAQPEIKVGVMPGAGGTQ 148 Query: 76 RLIRTVGKPLAMKMVLSGEFISADQALQAGLVAEVVDDDATLERTLALAHSIAQKSPLAV 135 RL+R VGK A++M+ +G + A QAL GLV+EVV D++TL R L LA IA+ PLA+ Sbjct: 149 RLVRAVGKFQALRMLFTGCLVKAPQALAMGLVSEVVADESTLARALELAMEIARLPPLAL 208 Query: 136 RLAKEAMLQSFELGLEAGLLFERKSFSLMAASADRQEGIAAFQEKRAAVFSGR 188 KE +L +L L++ L ERK+F L+ S D++EG+ AF EKR + G+ Sbjct: 209 AQIKEVVLAGADLPLDSALALERKAFQLLFDSQDQKEGMHAFLEKRPPNYQGK 261 >AF0435 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Afu Archaeoglobus fulgidus Length = 256 Score = 168 bits (425), Expect = 7e-42, Method: Compositional matrix adjust. Identities = 94/192 (48%), Positives = 124/192 (64%), Gaps = 6/192 (3%) Query: 1 MIHKDAI----ATQLDVRAQYWRAIARFPKPILAAVNGYALGAGCELLMHADIAIAARGA 56 ++ +DAI AT+L + I P++AAVNGY LG GCEL M DI IA+ A Sbjct: 67 LLQRDAIKAFEATKLGT--DLFSRIEELEIPVIAAVNGYTLGGGCELAMACDIRIASEKA 124 Query: 57 KIGQPEINVGTIPGAGGTQRLIRTVGKPLAMKMVLSGEFISADQALQAGLVAEVVDDDAT 116 K GQPEIN+ IPGAGGTQRL R VG +A K+VL+GE I A AL+ GLV EVV+ + Sbjct: 125 KFGQPEINLAIIPGAGGTQRLPRLVGLGMAKKLVLTGEIIDAQTALRIGLVEEVVEHERL 184 Query: 117 LERTLALAHSIAQKSPLAVRLAKEAMLQSFELGLEAGLLFERKSFSLMAASADRQEGIAA 176 +ER +A I +KSPLAV++AK+A+ S + L+ GL +E F+L+ +S D +EG+ A Sbjct: 185 MERAKEVAAKIIEKSPLAVKVAKKALNASINMPLKEGLRYEASLFALLFSSEDAKEGMRA 244 Query: 177 FQEKRAAVFSGR 188 F EKR F GR Sbjct: 245 FLEKRKPEFRGR 256 >BMEII1021 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Bme Brucella melitensis Length = 261 Score = 167 bits (424), Expect = 9e-42, Method: Compositional matrix adjust. Identities = 88/171 (51%), Positives = 114/171 (66%) Query: 18 WRAIARFPKPILAAVNGYALGAGCELLMHADIAIAARGAKIGQPEINVGTIPGAGGTQRL 77 W AIA KP++AAVNGYALG GCEL MH DI +A GA GQPE+ +G +PGAGGTQRL Sbjct: 91 WDAIASCAKPVIAAVNGYALGGGCELAMHCDIIVAGEGAVFGQPEVKLGLMPGAGGTQRL 150 Query: 78 IRTVGKPLAMKMVLSGEFISADQALQAGLVAEVVDDDATLERTLALAHSIAQKSPLAVRL 137 IR VGK AM++ L+G + A +AL G+++E+ ++ TL R LA IA+ LAV Sbjct: 151 IRAVGKFQAMRIALTGCMVPAAEALSIGMISEMTANERTLPRAHELAVEIARLPALAVAQ 210 Query: 138 AKEAMLQSFELGLEAGLLFERKSFSLMAASADRQEGIAAFQEKRAAVFSGR 188 KE ML +L L+ L ERK+F L+ S D++EG AAF EKR ++GR Sbjct: 211 IKEVMLVGADLPLDGALALERKAFQLLFDSKDQKEGAAAFLEKRKPAYNGR 261 >AF0963 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Afu Archaeoglobus fulgidus Length = 259 Score = 164 bits (414), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 82/159 (51%), Positives = 111/159 (69%) Query: 27 PILAAVNGYALGAGCELLMHADIAIAARGAKIGQPEINVGTIPGAGGTQRLIRTVGKPLA 86 P++AA+NG+ALG GCE+ M DI IA+ A GQPEIN+G IPGAGGTQRL R VG A Sbjct: 96 PVIAAINGFALGGGCEIAMACDIIIASERASFGQPEINLGIIPGAGGTQRLARIVGWKKA 155 Query: 87 MKMVLSGEFISADQALQAGLVAEVVDDDATLERTLALAHSIAQKSPLAVRLAKEAMLQSF 146 M++ L+GE ISA++A + GLV +VV+ D ++ +A I KSP AV L K+A+ + F Sbjct: 156 MELCLTGERISAEEAYRLGLVNKVVEHDKLMDEAKKMAEVIKSKSPYAVMLVKQAVNRGF 215 Query: 147 ELGLEAGLLFERKSFSLMAASADRQEGIAAFQEKRAAVF 185 ++GL G+++ER F+L +S D +EGI AF EKR A F Sbjct: 216 KMGLRDGIMYERDLFALSFSSPDAEEGIKAFVEKRKADF 254 >BMEI1945 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Bme Brucella melitensis Length = 293 Score = 163 bits (412), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 84/171 (49%), Positives = 112/171 (65%) Query: 18 WRAIARFPKPILAAVNGYALGAGCELLMHADIAIAARGAKIGQPEINVGTIPGAGGTQRL 77 W+ + R KPI+AAV+GYALG GCEL M D IA AK GQPEI +G IPG GG+QRL Sbjct: 123 WQKVDRIRKPIIAAVSGYALGGGCELAMMCDFIIAGSNAKFGQPEITLGAIPGMGGSQRL 182 Query: 78 IRTVGKPLAMKMVLSGEFISADQALQAGLVAEVVDDDATLERTLALAHSIAQKSPLAVRL 137 R VGK AM M L+G + A +A + GLV+ VV +A LE L A IA S ++V + Sbjct: 183 TRYVGKSKAMDMCLTGRMMDAAEAERCGLVSRVVAPEALLEEALKAAERIASFSRVSVYM 242 Query: 138 AKEAMLQSFELGLEAGLLFERKSFSLMAASADRQEGIAAFQEKRAAVFSGR 188 AKEA+ +++E L+ GL FER+ F + A+ D++EG++AF +KR F R Sbjct: 243 AKEAVNRAYETTLDEGLRFERRLFHSLFATEDQKEGMSAFVDKRTPSFKNR 293 >PA3591 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pae Pseudomonas aeruginosa Length = 265 Score = 160 bits (404), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 84/173 (48%), Positives = 115/173 (66%) Query: 16 QYWRAIARFPKPILAAVNGYALGAGCELLMHADIAIAARGAKIGQPEINVGTIPGAGGTQ 75 ++W+A+A KP++AAV G+ALG GCEL MH D+ +A A+ QPEI VG +PGAGGTQ Sbjct: 93 RHWQALAACRKPLIAAVEGHALGGGCELAMHCDLIVAGASARFAQPEIRVGVMPGAGGTQ 152 Query: 76 RLIRTVGKPLAMKMVLSGEFISADQALQAGLVAEVVDDDATLERTLALAHSIAQKSPLAV 135 RL+R VGK A++M+ +G + A +AL GLV+EV D L+R L LA IA PLA+ Sbjct: 153 RLVRAVGKFQALRMLFTGCTVRAPEALAIGLVSEVAADGQALDRALELARQIAGLPPLAL 212 Query: 136 RLAKEAMLQSFELGLEAGLLFERKSFSLMAASADRQEGIAAFQEKRAAVFSGR 188 KE +L +L L+ L ERK+F L+ S D++EG+ AF EKR A + G+ Sbjct: 213 AQIKEVVLAGADLPLDQALALERKAFQLLFDSHDQKEGMRAFLEKRTAEYLGK 265 >CC0006 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Ccr Caulobacter vibrioides Length = 262 Score = 160 bits (404), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 84/169 (49%), Positives = 113/169 (66%) Query: 19 RAIARFPKPILAAVNGYALGAGCELLMHADIAIAARGAKIGQPEINVGTIPGAGGTQRLI 78 RAI + KPI+AAV GYALG GCEL M D +AA AK GQPEIN+G PG GGTQRL Sbjct: 93 RAIEQCRKPIIAAVAGYALGGGCELAMMCDFILAADTAKFGQPEINLGVAPGIGGTQRLT 152 Query: 79 RTVGKPLAMKMVLSGEFISADQALQAGLVAEVVDDDATLERTLALAHSIAQKSPLAVRLA 138 R VGK AM M+L+G + A++A ++GLV+ + D+ ++ TLA+A IA +SPLAV + Sbjct: 153 RFVGKSKAMDMILTGRMMGAEEAERSGLVSRIFPADSLVDETLAIAAKIAGQSPLAVAMN 212 Query: 139 KEAMLQSFELGLEAGLLFERKSFSLMAASADRQEGIAAFQEKRAAVFSG 187 KE + ++E L G+ ER+ F + A D++EG+ AF EKR +F G Sbjct: 213 KELVEAAYETTLTTGVALERRLFHSLFAFEDQKEGMTAFVEKRKPLFKG 261 >BMEII0214 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Bme Brucella melitensis Length = 297 Score = 158 bits (399), Expect = 8e-39, Method: Compositional matrix adjust. Identities = 85/173 (49%), Positives = 112/173 (64%) Query: 16 QYWRAIARFPKPILAAVNGYALGAGCELLMHADIAIAARGAKIGQPEINVGTIPGAGGTQ 75 +YW ++A PKP++AAV GYALG GCEL MHADI +AAR A GQPEI +G +PGAGGTQ Sbjct: 125 RYWESLAHCPKPVIAAVEGYALGGGCELAMHADIIVAARTASFGQPEIKLGLMPGAGGTQ 184 Query: 76 RLIRTVGKPLAMKMVLSGEFISADQALQAGLVAEVVDDDATLERTLALAHSIAQKSPLAV 135 RL+R +GK M + L+GE + A +A + GLV+ + ++ LE L LA IA LA Sbjct: 185 RLLRAIGKYKTMLLALTGEMLPATEAEKYGLVSRLSEEGEALEEALKLARKIALMPALAA 244 Query: 136 RLAKEAMLQSFELGLEAGLLFERKSFSLMAASADRQEGIAAFQEKRAAVFSGR 188 KEA++ + LE L ERK+F L+ + D++EGI AF KR F GR Sbjct: 245 EQIKEAVMYGEDAPLETALRLERKAFQLLFDTEDKREGIDAFLTKRKPAFKGR 297 >BH0201 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Bha Bacillus halodurans Length = 257 Score = 157 bits (397), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 75/170 (44%), Positives = 117/170 (68%) Query: 18 WRAIARFPKPILAAVNGYALGAGCELLMHADIAIAARGAKIGQPEINVGTIPGAGGTQRL 77 W R KP++AAV+G+ALG G EL +H D+ +AA A+ G PE+++G +PGAGGTQ L Sbjct: 87 WDRFTRIHKPMVAAVSGFALGGGFELALHCDLIVAATNARFGFPEVSLGVLPGAGGTQLL 146 Query: 78 IRTVGKPLAMKMVLSGEFISADQALQAGLVAEVVDDDATLERTLALAHSIAQKSPLAVRL 137 R VG+ A++ + +G+ ISA +ALQ G++ ++V+ + E LA +I +++P+AVRL Sbjct: 147 TRAVGRKKALEWIWTGKHISAQEALQIGIINKIVEPELVEEEAFRLARTIVKQAPIAVRL 206 Query: 138 AKEAMLQSFELGLEAGLLFERKSFSLMAASADRQEGIAAFQEKRAAVFSG 187 KEA+ Q+ ++ L G++ ERK+F L A+ D++EG+ AF EKR +F G Sbjct: 207 IKEAVHQAEDVTLADGMMLERKNFYLAFATKDQKEGMKAFLEKRPPIFKG 256