BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0031.0096.p (216 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value NMB1579 [E] COG0040 ATP phosphoribosyltransferase Nme Neisseria ... 309 3e-84 NMA1768 [E] COG0040 ATP phosphoribosyltransferase NmA Neisseria ... 309 3e-84 PA4449 [E] COG0040 ATP phosphoribosyltransferase Pae Pseudomonas... 247 2e-65 BS_hisG [E] COG0040 ATP phosphoribosyltransferase Bsu Bacillus s... 184 1e-46 BH3583 [E] COG0040 ATP phosphoribosyltransferase Bha Bacillus ha... 171 9e-43 DR1445 [E] COG0040 ATP phosphoribosyltransferase Dra Deinococcus... 167 1e-41 CAC0936 [E] COG0040 ATP phosphoribosyltransferase Cac Clostridiu... 165 6e-41 lin0577 [E] COG0040 ATP phosphoribosyltransferase Lin Listeria i... 157 1e-38 sll0900 [E] COG0040 ATP phosphoribosyltransferase Syn Synechocystis 144 2e-34 alr1965 [E] COG0040 ATP phosphoribosyltransferase Nos Nostoc sp.... 142 6e-34 >NMB1579 [E] COG0040 ATP phosphoribosyltransferase Nme Neisseria meningitidis MC58 Length = 217 Score = 309 bits (791), Expect = 3e-84, Method: Compositional matrix adjust. Identities = 151/212 (71%), Positives = 177/212 (83%) Query: 5 LTLALSKGRIFEETLPLLKAAGITVSEDPESSRKLILPTNDPDVRVIIVRASDVPTYVQY 64 LT+ALSKGRIFEETLPLL AAGI +E+PE SRKLI+ TN ++R++IVRA+DVPTYV+Y Sbjct: 6 LTIALSKGRIFEETLPLLAAAGIVPTEEPEKSRKLIIGTNHENIRLVIVRATDVPTYVRY 65 Query: 65 GAADFGVAGKDVLLEHGGEGLYQPIDLNIAKCRLSVAVQEGFDYANAVRQGARLRVVTKY 124 GAADFG+AGKDVL+EHGG GLY+P+DL IAKCR+ VAV++GFDY A + G RL++ TKY Sbjct: 66 GAADFGIAGKDVLIEHGGTGLYRPLDLEIAKCRMMVAVRKGFDYEAASQPGCRLKIATKY 125 Query: 125 VNTAREHFAAKGVHVDLIKLYGSMELGPLVGLSDAIVDLVSTGGTLRANKLVEVEHIIDI 184 A HFA KGVHVD+IKLYGSMEL PLVGLSDAIVDLVSTG TL+AN L VEHI+DI Sbjct: 126 PEIAASHFAGKGVHVDIIKLYGSMELAPLVGLSDAIVDLVSTGNTLKANGLEAVEHIVDI 185 Query: 185 SSRLVVNQAALKLKRERLQPILDAFEKASKAK 216 SSRLVVN+AALK K L+PI+ AF A KAK Sbjct: 186 SSRLVVNKAALKTKYALLEPIIQAFGGAVKAK 217 >NMA1768 [E] COG0040 ATP phosphoribosyltransferase NmA Neisseria meningitidis Z2491 Length = 217 Score = 309 bits (791), Expect = 3e-84, Method: Compositional matrix adjust. Identities = 151/212 (71%), Positives = 177/212 (83%) Query: 5 LTLALSKGRIFEETLPLLKAAGITVSEDPESSRKLILPTNDPDVRVIIVRASDVPTYVQY 64 LT+ALSKGRIFEETLPLL AAGI +E+PE SRKLI+ TN ++R++IVRA+DVPTYV+Y Sbjct: 6 LTIALSKGRIFEETLPLLAAAGIVPTEEPEKSRKLIIGTNHENIRLVIVRATDVPTYVRY 65 Query: 65 GAADFGVAGKDVLLEHGGEGLYQPIDLNIAKCRLSVAVQEGFDYANAVRQGARLRVVTKY 124 GAADFG+AGKDVL+EHGG GLY+P+DL IAKCR+ VAV++GFDY A + G RL++ TKY Sbjct: 66 GAADFGIAGKDVLIEHGGTGLYRPLDLEIAKCRMMVAVRKGFDYEAASQPGCRLKIATKY 125 Query: 125 VNTAREHFAAKGVHVDLIKLYGSMELGPLVGLSDAIVDLVSTGGTLRANKLVEVEHIIDI 184 A HFA KGVHVD+IKLYGSMEL PLVGLSDAIVDLVSTG TL+AN L VEHI+DI Sbjct: 126 PEIAASHFAGKGVHVDIIKLYGSMELAPLVGLSDAIVDLVSTGNTLKANGLEAVEHIVDI 185 Query: 185 SSRLVVNQAALKLKRERLQPILDAFEKASKAK 216 SSRLVVN+AALK K L+PI+ AF A KAK Sbjct: 186 SSRLVVNKAALKTKYALLEPIIQAFGGAVKAK 217 >PA4449 [E] COG0040 ATP phosphoribosyltransferase Pae Pseudomonas aeruginosa Length = 211 Score = 247 bits (630), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 125/212 (58%), Positives = 162/212 (76%), Gaps = 5/212 (2%) Query: 5 LTLALSKGRIFEETLPLLKAAGITVSEDPESSRKLILPTNDPDVRVIIVRASDVPTYVQY 64 LT+ALSKGRI ++TLPLL AAGI SE+P+ SRKLI+PT+ DVR++IVRA+DVPTYV++ Sbjct: 2 LTIALSKGRILDDTLPLLAAAGIVPSENPDKSRKLIIPTSLSDVRLLIVRATDVPTYVEH 61 Query: 65 GAADFGVAGKDVLLEHGGEGLYQPIDLNIAKCRLSVAVQEGFDYANAVRQGARLRVVTKY 124 GAAD GVAGKDVL+E+GG+GLY+P+DL IA C+L A G A RLRV TK+ Sbjct: 62 GAADLGVAGKDVLMEYGGQGLYEPLDLRIANCKLMTAGAIG-----APEPKGRLRVATKF 116 Query: 125 VNTAREHFAAKGVHVDLIKLYGSMELGPLVGLSDAIVDLVSTGGTLRANKLVEVEHIIDI 184 VN A+ ++A +G VD+IKLYGSMEL PLVGL+D I+D+V TG TLRAN L E I I Sbjct: 117 VNVAKRYYAEQGRQVDVIKLYGSMELAPLVGLADKIIDVVDTGNTLRANGLEPQELIATI 176 Query: 185 SSRLVVNQAALKLKRERLQPILDAFEKASKAK 216 SSRLVVN+A++K++ R+Q ++D A +A+ Sbjct: 177 SSRLVVNKASMKMQHGRIQSLIDTLRDAVEAR 208 >BS_hisG [E] COG0040 ATP phosphoribosyltransferase Bsu Bacillus subtilis Length = 213 Score = 184 bits (467), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 96/198 (48%), Positives = 135/198 (68%), Gaps = 6/198 (3%) Query: 1 MTQQLTLALSKGRIFEETLPLLKAAGITVSEDPESSRKLILPTNDPDVRVIIVRASDVPT 60 M + LT+A+ KGRIFEE LL+ AG + E+ E SRKLI+ + ++R I+ + DV T Sbjct: 1 MGKLLTMAMPKGRIFEEAAGLLRQAGYRLPEEFEDSRKLIIDVPEENLRFILAKPMDVTT 60 Query: 61 YVQYGAADFGVAGKDVLLEHGGEGLYQPIDLNIAKCRLSVAVQEGFDYANAVRQGARLRV 120 YV++G AD G+AGKDV+LE + +Y+ +DLNI+KC L+VA D++ G R+ Sbjct: 61 YVEHGVADVGIAGKDVMLEEERD-VYEVLDLNISKCHLAVAGLPNTDWS-----GVAPRI 114 Query: 121 VTKYVNTAREHFAAKGVHVDLIKLYGSMELGPLVGLSDAIVDLVSTGGTLRANKLVEVEH 180 TKY N A +F +G V++IKL GS+EL PL+GL+D IVD+VSTG TL+ N LVE EH Sbjct: 115 ATKYPNVASSYFREQGEQVEIIKLNGSIELAPLIGLADRIVDIVSTGQTLKENGLVETEH 174 Query: 181 IIDISSRLVVNQAALKLK 198 I DI+SR +VN + ++K Sbjct: 175 ICDITSRFIVNPVSYRMK 192 >BH3583 [E] COG0040 ATP phosphoribosyltransferase Bha Bacillus halodurans Length = 212 Score = 171 bits (434), Expect = 9e-43, Method: Compositional matrix adjust. Identities = 90/203 (44%), Positives = 141/203 (69%), Gaps = 5/203 (2%) Query: 5 LTLALSKGRIFEETLPLLKAAGITVSEDPESSRKLILPTNDPDVRVIIVRASDVPTYVQY 64 LT+A+ KGRIF+E + LL+ AG + + E+SRKLI+ + ++R I+ + DVPTYV++ Sbjct: 4 LTVAMPKGRIFDEAVGLLRKAGYNLPAEFEASRKLIVDVPEENMRFILAKPMDVPTYVEH 63 Query: 65 GAADFGVAGKDVLLEHGGEGLYQPIDLNIAKCRLSVAVQEGFDYANAVRQGARLRVVTKY 124 G AD GVAGKDV+LE + +Y+ +DL I++C L+VA ++ + + +V +KY Sbjct: 64 GVADVGVAGKDVMLEEERD-VYEVLDLKISECYLAVAGLPNYEKKHDLNP----KVASKY 118 Query: 125 VNTAREHFAAKGVHVDLIKLYGSMELGPLVGLSDAIVDLVSTGGTLRANKLVEVEHIIDI 184 + A +F +G V++IKL GS+EL PL+GL+D IVD+VSTG TLR N LVE+E ++ I Sbjct: 119 PHLATRYFKEQGEQVEIIKLNGSIELAPLIGLADRIVDIVSTGRTLRENGLVELEKMMTI 178 Query: 185 SSRLVVNQAALKLKRERLQPILD 207 +SRL+VN + ++K ER+ +++ Sbjct: 179 TSRLIVNPVSYRMKDERIDEMVE 201 >DR1445 [E] COG0040 ATP phosphoribosyltransferase Dra Deinococcus radiodurans Length = 218 Score = 167 bits (423), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 95/203 (46%), Positives = 132/203 (65%), Gaps = 11/203 (5%) Query: 4 QLTLALSKGRIFEETLPLLKAAGITVSEDPESSRKLILPTNDPDVRVIIVRASDVPTYVQ 63 LTLAL KGRI ++ + LL AG+ ++ PE+SR L P V V+ +R DVP YV Sbjct: 13 HLTLALPKGRIMDDAIALLSQAGLPLTR-PEASRALR--HEFPGVTVLELRNQDVPVYVD 69 Query: 64 YGAADFGVAGKDVLLEHGGEGLYQPIDLNIAKCRLSVAVQEGFDYANAVRQGARLRVVTK 123 G AD G+ GKDVLLE G +Y+P+DL+ A+CRLS+ + G G RV TK Sbjct: 70 LGVADAGIVGKDVLLE-AGRPVYEPVDLHFAECRLSLIREIGA-------SGPIARVGTK 121 Query: 124 YVNTAREHFAAKGVHVDLIKLYGSMELGPLVGLSDAIVDLVSTGGTLRANKLVEVEHIID 183 Y AR + +G+ +++KL G++EL L GL+DA++DLV TG TLRAN L EV+ + Sbjct: 122 YPRAARAYLQERGIPAEVVKLSGNIELAALTGLADAVIDLVQTGSTLRANHLEEVDVLFH 181 Query: 184 ISSRLVVNQAALKLKRERLQPIL 206 S+RL+VN+ ALKL+RERL+P++ Sbjct: 182 SSARLIVNRTALKLRRERLRPLI 204 >CAC0936 [E] COG0040 ATP phosphoribosyltransferase Cac Clostridium acetobutylicum Length = 215 Score = 165 bits (418), Expect = 6e-41, Method: Compositional matrix adjust. Identities = 84/211 (39%), Positives = 135/211 (63%), Gaps = 16/211 (7%) Query: 2 TQQLTLALSKGRIFEETLPLLKAAGITVSEDPESSRKLILPTNDPDVRVIIVRASDVPTY 61 + + +AL+KGR+ + + + + G+ SE + RKLI + ++V+A DV TY Sbjct: 4 NKTIRIALTKGRLEKAAVEIFENIGLDCSELKDKGRKLIFHDFKNSIDFVLVKAPDVLTY 63 Query: 62 VQYGAADFGVAGKDVLLEHGGEGLYQPIDLNIAKCRLSVA------VQEGFDYANAVRQG 115 V++GAAD G+ GKD LLE + Y+ +DL + KC+ S+A + EGF+ Sbjct: 64 VEHGAADIGIVGKDTLLEMKKD-FYEVLDLKVGKCKFSLASISSFKLNEGFN-------- 114 Query: 116 ARLRVVTKYVNTAREHFAAKGVHVDLIKLYGSMELGPLVGLSDAIVDLVSTGGTLRANKL 175 R+++ TKY N RE+F KG+ V++IK+ GS+EL P++ L+DAIVD+V TG TL+ N L Sbjct: 115 -RMKIATKYPNVTREYFREKGIDVEIIKIEGSVELAPILNLADAIVDIVETGTTLKENGL 173 Query: 176 VEVEHIIDISSRLVVNQAALKLKRERLQPIL 206 V + I DIS+R++VN+A++KL ++R+ I+ Sbjct: 174 VIFDDICDISARMIVNRASMKLNKDRITDII 204 >lin0577 [E] COG0040 ATP phosphoribosyltransferase Lin Listeria innocua Length = 213 Score = 157 bits (397), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 85/210 (40%), Positives = 136/210 (64%), Gaps = 5/210 (2%) Query: 5 LTLALSKGRIFEETLPLLKAAGITVSEDPESSRKLILPTNDPDVRVIIVRASDVPTYVQY 64 L +AL+KGR+ ++ + LL+ AGI S + RKLI ++ + I+V+A DV TYV++ Sbjct: 4 LKIALTKGRLEKDAVALLEKAGIDCSSMNDKKRKLIFHSSTQPISFILVKAVDVMTYVKH 63 Query: 65 GAADFGVAGKDVLLEHGGEGLYQPIDLNIAKCRLSVAVQEGFDYANAVRQGARLRVVTKY 124 G AD G+ GKDVL+E + Y+ +DL I +C+ +A FD ++ R+ + TKY Sbjct: 64 GVADIGIVGKDVLME-ASKSHYEMLDLEIGQCQFCLASTPDFDPSSYRRK----IIATKY 118 Query: 125 VNTAREHFAAKGVHVDLIKLYGSMELGPLVGLSDAIVDLVSTGGTLRANKLVEVEHIIDI 184 + + F AKG V++IK+ GS+E+ P++GL+DAI+D+V TG TL+ N LV E + I Sbjct: 119 PAVSSKFFRAKGEDVEIIKIEGSVEIAPVLGLADAIIDIVETGSTLKENGLVIYEKMYPI 178 Query: 185 SSRLVVNQAALKLKRERLQPILDAFEKASK 214 S+RL+VN+A+LK + ++ ++D E+A K Sbjct: 179 SARLIVNKASLKQNKTQIFQLIDQLEQAIK 208 >sll0900 [E] COG0040 ATP phosphoribosyltransferase Syn Synechocystis Length = 210 Score = 144 bits (362), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 87/210 (41%), Positives = 129/210 (61%), Gaps = 9/210 (4%) Query: 5 LTLALSKGRIFEETLPLLKAAGITVSE--DPESSRKLIL-PTNDPDVRVIIVRASDVPTY 61 LT+AL KG + +++ + G+ S +P++ + IL PT+ + ++VRA DVP Y Sbjct: 2 LTIALPKGSLLRDSIDRFQQIGLDFSAFLEPKNRQLQILDPTHR--AKALLVRAWDVPVY 59 Query: 62 VQYGAADFGVAGKDVLLEHGGEGLYQPIDLNIAKCRLSVAVQEGFDYANAVRQGARLRVV 121 V+YG A G+ G D+L E + Q DLN CRLSVAV + Y +V RV Sbjct: 60 VEYGQAQLGIVGYDILREKK-PAVAQLADLNFGGCRLSVAVPQASPYRRSVDLPPHGRVA 118 Query: 122 TKYVNTAREHFAAKGVHVDLIKLYGSMELGPLVGLSDAIVDLVSTGGTLRANKLVEVEHI 181 +K+V+ A EHF + V++I LYGS+ELGP+ G+S+AIVDLVSTG TL+ N L+E+E + Sbjct: 119 SKFVHCALEHFRRLDLPVEIIPLYGSVELGPITGMSEAIVDLVSTGRTLQENGLMEIEVL 178 Query: 182 IDISSRLVVNQAALKLKRERLQPILDAFEK 211 D S+RL+ + + ++ +RL LD EK Sbjct: 179 FDSSARLIAHPLSYRVNGDRL---LDWVEK 205 >alr1965 [E] COG0040 ATP phosphoribosyltransferase Nos Nostoc sp. PCC 7120 Length = 214 Score = 142 bits (357), Expect = 6e-34, Method: Compositional matrix adjust. Identities = 81/218 (37%), Positives = 129/218 (59%), Gaps = 12/218 (5%) Query: 5 LTLALSKGRIFEETLPLLKAAGITVSEDPES-SRKLILPTNDPDVRVIIVRASDVPTYVQ 63 LT+AL KG + + ++ LL++ G+ S +S +R+L + + ++VR DVP YV+ Sbjct: 2 LTVALPKGELLKNSIRLLQSVGLDFSAFLDSGNRQLQITDASGTAKGLLVRGQDVPVYVE 61 Query: 64 YGAADFGVAGKDVLLEHGGEGLYQP-----IDLNIAKCRLSVAVQEGFDYANAVRQGARL 118 YG A G+ G DVL E QP +DL CR+SVAV+ Y + + A Sbjct: 62 YGQAQIGIIGYDVLREK------QPQVAHLVDLQFGYCRMSVAVKASSPYKSPLDLPAHS 115 Query: 119 RVVTKYVNTAREHFAAKGVHVDLIKLYGSMELGPLVGLSDAIVDLVSTGGTLRANKLVEV 178 RV +KYVN+ARE F + V+++ LYGS+ELGP+ G+S+AIVD+VSTG TL+ N LVE+ Sbjct: 116 RVASKYVNSAREFFQGLDLPVEIVPLYGSVELGPITGMSEAIVDIVSTGRTLKENGLVEI 175 Query: 179 EHIIDISSRLVVNQAALKLKRERLQPILDAFEKASKAK 216 + + ++RL+ + + +L L +++ + + K Sbjct: 176 TTLYESTARLIAHPLSYRLNTGNLHQLVEQLREGALTK 213