BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0031.0092.p (198 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2950 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Rso ... 338 5e-93 PA5143 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Pae P... 326 2e-89 NMB1583 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Nme ... 313 2e-85 NMA1772 [E] COG0131 Imidazoleglycerol-phosphate dehydratase NmA ... 313 2e-85 all4390 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Nos ... 246 3e-65 slr0500 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Syn ... 236 2e-62 SMc02574 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Sme... 236 2e-62 AGc69 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Atu Ag... 226 3e-59 CC3734 Non COG 223 2e-58 BMEI2045 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Bme... 212 5e-55 >RSc2950 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Rso Ralstonia solanacearum Length = 196 Score = 338 bits (866), Expect = 5e-93, Method: Compositional matrix adjust. Identities = 163/194 (84%), Positives = 179/194 (92%) Query: 5 RTAEVVRNTNETQIRVAINLDGTGQQKLDTGVPFLDHMLDQIARHGLIDLDVHAKGDLHI 64 R AEV RNT+ETQIRVA++LDGTG+Q L+TGVPFLDHMLDQIARHG++DLDV A GD HI Sbjct: 3 RRAEVTRNTSETQIRVALDLDGTGKQTLNTGVPFLDHMLDQIARHGMVDLDVTATGDTHI 62 Query: 65 DAHHTVEDVGITLGMAFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDFSGRPGLEYHIPF 124 D HHTVEDVGITLG A AKAIGDKKGI RYGH+YVPLDEALSRVVIDFSGRPGLE+H+PF Sbjct: 63 DDHHTVEDVGITLGQAVAKAIGDKKGIVRYGHSYVPLDEALSRVVIDFSGRPGLEFHVPF 122 Query: 125 TRSMIGSFDVDLTSEFFHGFVNHAQVTLHVDNLRGVNAHHQAETVFKAFGRALRMAVELD 184 TR+ +GSFDVDL+ EFF GFVNHA VTLH+DNLRGVNAHHQ ETVFKAFGRALRMAVE+D Sbjct: 123 TRARVGSFDVDLSIEFFRGFVNHAGVTLHIDNLRGVNAHHQIETVFKAFGRALRMAVEID 182 Query: 185 PRAAGTIPSTKGSL 198 PRAAGTIPSTKG+L Sbjct: 183 PRAAGTIPSTKGAL 196 >PA5143 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Pae Pseudomonas aeruginosa Length = 197 Score = 326 bits (835), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 155/194 (79%), Positives = 171/194 (88%) Query: 5 RTAEVVRNTNETQIRVAINLDGTGQQKLDTGVPFLDHMLDQIARHGLIDLDVHAKGDLHI 64 R A V R+T ETQI+V+I+LDGTG+ + DTGVPFLDHM+DQIARHGLIDLD+ KGDLHI Sbjct: 4 RKASVARDTLETQIKVSIDLDGTGKARFDTGVPFLDHMMDQIARHGLIDLDIECKGDLHI 63 Query: 65 DAHHTVEDVGITLGMAFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDFSGRPGLEYHIPF 124 D HHTVED+GITLG AFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDFSGRPGL+ H+PF Sbjct: 64 DDHHTVEDIGITLGQAFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDFSGRPGLQMHVPF 123 Query: 125 TRSMIGSFDVDLTSEFFHGFVNHAQVTLHVDNLRGVNAHHQAETVFKAFGRALRMAVELD 184 TR+ +G FDVDL EFF GFVNHAQVTLH+DNLRG N HHQ ETVFKAFGRALRMA+ELD Sbjct: 124 TRASVGGFDVDLFMEFFQGFVNHAQVTLHIDNLRGHNTHHQIETVFKAFGRALRMAIELD 183 Query: 185 PRAAGTIPSTKGSL 198 R AG +PSTKG L Sbjct: 184 ERMAGQMPSTKGCL 197 >NMB1583 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Nme Neisseria meningitidis MC58 Length = 305 Score = 313 bits (801), Expect = 2e-85, Method: Compositional matrix adjust. Identities = 146/194 (75%), Positives = 167/194 (86%) Query: 5 RTAEVVRNTNETQIRVAINLDGTGQQKLDTGVPFLDHMLDQIARHGLIDLDVHAKGDLHI 64 R+ V RNT ETQI V+INLDG+G+ +LDTGVPFL+HM+DQIARHG+ID+D+ KGDLHI Sbjct: 110 RSVTVNRNTCETQITVSINLDGSGKSRLDTGVPFLEHMIDQIARHGMIDIDISCKGDLHI 169 Query: 65 DAHHTVEDVGITLGMAFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDFSGRPGLEYHIPF 124 D HHT ED+GITLG A +A+GDKKGIRRYGH+YVPLDEALSRVVID SGRPGL Y+I F Sbjct: 170 DDHHTAEDIGITLGQAIRQALGDKKGIRRYGHSYVPLDEALSRVVIDLSGRPGLVYNIEF 229 Query: 125 TRSMIGSFDVDLTSEFFHGFVNHAQVTLHVDNLRGVNAHHQAETVFKAFGRALRMAVELD 184 TR++IG FDVDL EFFHG VNH+ +TLH+DNL G NAHHQAETVFKAFGRALRMAVE D Sbjct: 230 TRALIGRFDVDLFEEFFHGIVNHSMMTLHIDNLSGKNAHHQAETVFKAFGRALRMAVEHD 289 Query: 185 PRAAGTIPSTKGSL 198 PR AG PSTKG+L Sbjct: 290 PRMAGQTPSTKGTL 303 >NMA1772 [E] COG0131 Imidazoleglycerol-phosphate dehydratase NmA Neisseria meningitidis Z2491 Length = 305 Score = 313 bits (801), Expect = 2e-85, Method: Compositional matrix adjust. Identities = 146/194 (75%), Positives = 167/194 (86%) Query: 5 RTAEVVRNTNETQIRVAINLDGTGQQKLDTGVPFLDHMLDQIARHGLIDLDVHAKGDLHI 64 R+ V RNT ETQI V+INLDG+G+ +LDTGVPFL+HM+DQIARHG+ID+D+ KGDLHI Sbjct: 110 RSVTVNRNTCETQITVSINLDGSGKSRLDTGVPFLEHMIDQIARHGMIDIDISCKGDLHI 169 Query: 65 DAHHTVEDVGITLGMAFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDFSGRPGLEYHIPF 124 D HHT ED+GITLG A +A+GDKKGIRRYGH+YVPLDEALSRVVID SGRPGL Y+I F Sbjct: 170 DDHHTAEDIGITLGQAIRQALGDKKGIRRYGHSYVPLDEALSRVVIDLSGRPGLVYNIEF 229 Query: 125 TRSMIGSFDVDLTSEFFHGFVNHAQVTLHVDNLRGVNAHHQAETVFKAFGRALRMAVELD 184 TR++IG FDVDL EFFHG VNH+ +TLH+DNL G NAHHQAETVFKAFGRALRMAVE D Sbjct: 230 TRALIGRFDVDLFEEFFHGIVNHSMMTLHIDNLSGKNAHHQAETVFKAFGRALRMAVEHD 289 Query: 185 PRAAGTIPSTKGSL 198 PR AG PSTKG+L Sbjct: 290 PRMAGQTPSTKGTL 303 >all4390 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Nos Nostoc sp. PCC 7120 Length = 209 Score = 246 bits (627), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 120/197 (60%), Positives = 143/197 (72%) Query: 2 STPRTAEVVRNTNETQIRVAINLDGTGQQKLDTGVPFLDHMLDQIARHGLIDLDVHAKGD 61 S PR A V R T ET ++V +NLDGTG K TG+PFLDHML QI+ HGLIDLDV AKGD Sbjct: 13 SVPRIASVHRITGETNVQVTVNLDGTGICKAATGIPFLDHMLHQISSHGLIDLDVQAKGD 72 Query: 62 LHIDAHHTVEDVGITLGMAFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDFSGRPGLEYH 121 ID HHT EDVGITLG A AKA+GD+KGI R+G+ PLDEAL +V +DFSGRP L Y Sbjct: 73 WEIDDHHTNEDVGITLGQALAKALGDRKGIVRFGNFLAPLDEALVQVALDFSGRPHLSYG 132 Query: 122 IPFTRSMIGSFDVDLTSEFFHGFVNHAQVTLHVDNLRGVNAHHQAETVFKAFGRALRMAV 181 + +G++D L EFF VNH+Q+TLH+ L G+N+HH E FKAF RA RMA+ Sbjct: 133 LQIPTERVGTYDTQLVREFFVALVNHSQMTLHIRQLDGINSHHIIEATFKAFARAARMAI 192 Query: 182 ELDPRAAGTIPSTKGSL 198 E+DPR AGTIPS+KG L Sbjct: 193 EVDPRRAGTIPSSKGVL 209 >slr0500 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Syn Synechocystis Length = 210 Score = 236 bits (603), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 115/195 (58%), Positives = 143/195 (73%) Query: 4 PRTAEVVRNTNETQIRVAINLDGTGQQKLDTGVPFLDHMLDQIARHGLIDLDVHAKGDLH 63 PR A V R T ET +RV++NL G+G + TGVPFLDHML QIA HGLIDL+V+A GD+ Sbjct: 16 PRAAAVHRVTKETDVRVSLNLMGSGLCHVATGVPFLDHMLHQIASHGLIDLEVNATGDIE 75 Query: 64 IDAHHTVEDVGITLGMAFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDFSGRPGLEYHIP 123 ID HHT EDVGITLG A A+A+GD++GI R+GH PLDEAL +V +DFSGRP L Y + Sbjct: 76 IDDHHTNEDVGITLGQALAEALGDRRGINRFGHFIAPLDEALVQVTLDFSGRPHLSYGLQ 135 Query: 124 FTRSMIGSFDVDLTSEFFHGFVNHAQVTLHVDNLRGVNAHHQAETVFKAFGRALRMAVEL 183 +G++D L EFF VNH+Q+TLH+ L G+N+HH E FKAF RA+RMA+E+ Sbjct: 136 IPTERVGTYDTQLVREFFVAVVNHSQMTLHIRQLDGINSHHIIEATFKAFARAMRMAIEV 195 Query: 184 DPRAAGTIPSTKGSL 198 DPR A TIPS+KG L Sbjct: 196 DPRRADTIPSSKGVL 210 >SMc02574 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Sme Sinorhizobium meliloti Length = 202 Score = 236 bits (603), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 107/194 (55%), Positives = 139/194 (71%) Query: 5 RTAEVVRNTNETQIRVAINLDGTGQQKLDTGVPFLDHMLDQIARHGLIDLDVHAKGDLHI 64 RT +V R TNET I V++N+DGTG K+ TGV F DHMLDQ++RH LID+++ A+GDLH+ Sbjct: 8 RTGQVSRKTNETAISVSVNVDGTGVSKIATGVGFFDHMLDQLSRHSLIDMEIKAEGDLHV 67 Query: 65 DAHHTVEDVGITLGMAFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDFSGRPGLEYHIPF 124 D HHTVED GI +G A AKA+GD++GI RY + +DE ++R +D SGRP L +++ F Sbjct: 68 DDHHTVEDTGIAIGQALAKALGDRRGITRYASIDLAMDETMTRAAVDVSGRPFLVWNVTF 127 Query: 125 TRSMIGSFDVDLTSEFFHGFVNHAQVTLHVDNLRGVNAHHQAETVFKAFGRALRMAVELD 184 T IG+FD +L EFF HA +TLHV N+ G N HH AET FK+ R LR A E+D Sbjct: 128 TSPKIGTFDTELVREFFQALAQHAGITLHVQNIYGANNHHVAETCFKSVARVLRTATEID 187 Query: 185 PRAAGTIPSTKGSL 198 PR AG +PSTKG+L Sbjct: 188 PRQAGRVPSTKGTL 201 >AGc69 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 214 Score = 226 bits (576), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 102/194 (52%), Positives = 136/194 (70%) Query: 5 RTAEVVRNTNETQIRVAINLDGTGQQKLDTGVPFLDHMLDQIARHGLIDLDVHAKGDLHI 64 R E++R TNET + V +++DGTG+ K+ TGV F DHMLDQ++RH LID+D+ +GDLHI Sbjct: 20 RKGEIIRKTNETSVSVRVDIDGTGKSKISTGVGFFDHMLDQLSRHSLIDMDIEVQGDLHI 79 Query: 65 DAHHTVEDVGITLGMAFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDFSGRPGLEYHIPF 124 D HHTVED GI +G A AKA+GD++GI RY + +DE +++ +D SGRP L +++ F Sbjct: 80 DDHHTVEDTGIAIGQAIAKALGDRRGITRYASLDLAMDETMTKAAVDISGRPFLVWNVNF 139 Query: 125 TRSMIGSFDVDLTSEFFHGFVNHAQVTLHVDNLRGVNAHHQAETVFKAFGRALRMAVELD 184 + IG+FD +L EFF +A +TLH+ N G N HH AET FKA R LR A E+D Sbjct: 140 SAPKIGTFDTELVREFFQALAQNAGITLHILNHYGANNHHIAETCFKAVARVLRTATEID 199 Query: 185 PRAAGTIPSTKGSL 198 PR AG +PSTKG L Sbjct: 200 PRQAGRVPSTKGML 213 >CC3734 Non COG Length = 196 Score = 223 bits (568), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 109/194 (56%), Positives = 130/194 (67%) Query: 5 RTAEVVRNTNETQIRVAINLDGTGQQKLDTGVPFLDHMLDQIARHGLIDLDVHAKGDLHI 64 RTAEVVR T ETQIRV I+LDGTG + TG+ F DHML+ ARHG DL V KGDLHI Sbjct: 3 RTAEVVRETKETQIRVWIDLDGTGVSTISTGIGFYDHMLESFARHGGFDLKVETKGDLHI 62 Query: 65 DAHHTVEDVGITLGMAFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDFSGRPGLEYHIPF 124 D HHTVED GI LG A KA+ KGIRR+G AY+P+DE L+R ID S RP L + + F Sbjct: 63 DMHHTVEDTGIVLGQAIHKALDGFKGIRRFGSAYIPMDETLTRCAIDLSNRPYLIWKVEF 122 Query: 125 TRSMIGSFDVDLTSEFFHGFVNHAQVTLHVDNLRGVNAHHQAETVFKAFGRALRMAVELD 184 R +G D +L EF H F ++ +H++ L G N HH AE+ FKA RALR AVE+D Sbjct: 123 KRPKVGEMDTELFKEFHHAFAMNSGACIHLETLYGDNTHHVAESGFKALARALRQAVEID 182 Query: 185 PRAAGTIPSTKGSL 198 P+ G PSTKG L Sbjct: 183 PKTGGQAPSTKGVL 196 >BMEI2045 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Bme Brucella melitensis Length = 202 Score = 212 bits (539), Expect = 5e-55, Method: Compositional matrix adjust. Identities = 102/196 (52%), Positives = 135/196 (68%) Query: 3 TPRTAEVVRNTNETQIRVAINLDGTGQQKLDTGVPFLDHMLDQIARHGLIDLDVHAKGDL 62 + R A + R+T ET I V+++LDG G+ + TGV F DHML+Q++RH LID+ V AKGDL Sbjct: 5 STRKASIERSTKETSIAVSVDLDGVGKFDITTGVGFFDHMLEQLSRHSLIDMRVMAKGDL 64 Query: 63 HIDAHHTVEDVGITLGMAFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDFSGRPGLEYHI 122 HID HHTVED GI LG A AKA+G+++GI RY + +D+ L+ +D SGR L +++ Sbjct: 65 HIDDHHTVEDTGIALGQAVAKALGERRGIVRYASLDLAMDDTLTGAAVDVSGRAFLVWNV 124 Query: 123 PFTRSMIGSFDVDLTSEFFHGFVNHAQVTLHVDNLRGVNAHHQAETVFKAFGRALRMAVE 182 FT + IG+FD +L EFF F +A +TLH++N G N HH AE+ FKA R LR A+E Sbjct: 125 NFTTAKIGTFDTELVREFFQAFAMNAGITLHINNHYGANNHHIAESTFKAVARVLRAALE 184 Query: 183 LDPRAAGTIPSTKGSL 198 DPR IPSTKGSL Sbjct: 185 TDPRQKDAIPSTKGSL 200