BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0031.0027.p (266 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BMEII0642 [K] COG1414 Transcriptional regulator Bme Brucella mel... 231 1e-60 AGl644 [K] COG1414 Transcriptional regulator Atu Agrobacterium t... 228 1e-59 SMb20586 [K] COG1414 Transcriptional regulator Sme Sinorhizobium... 225 7e-59 Cgl2340 [K] COG1414 Transcriptional regulator Cgl Corynebacteriu... 204 1e-52 mlr4184 [K] COG1414 Transcriptional regulator Mlo Mesorhizobium ... 192 9e-49 RSc2255 [K] COG1414 Transcriptional regulator Rso Ralstonia sola... 181 1e-45 PA0155 [K] COG1414 Transcriptional regulator Pae Pseudomonas aer... 172 7e-43 RSc3411 [K] COG1414 Transcriptional regulator Rso Ralstonia sola... 145 9e-35 PA3508 [K] COG1414 Transcriptional regulator Pae Pseudomonas aer... 114 3e-25 DR1156 [K] COG1414 Transcriptional regulator Dra Deinococcus rad... 108 9e-24 >BMEII0642 [K] COG1414 Transcriptional regulator Bme Brucella melitensis Length = 256 Score = 231 bits (590), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 123/246 (50%), Positives = 167/246 (67%) Query: 21 DLVAGLEKGLQVIEAFDQERSRLTIAEVAQLTGLTRAAARRYLITLTHLGYMRHDNKTFS 80 D V G KGL+VIEAF ++R RL+IA+V+++TGL RA ARR L+TL LGY +D K F Sbjct: 5 DFVGGFAKGLRVIEAFGEDRPRLSIADVSKITGLDRATARRCLLTLAELGYAEYDGKFFM 64 Query: 81 LTPMVLRLGQSYLHSARLPRIVQPLLYRLAYSLGEAASCGVLDHDQLVCVAAVSAGQLVS 140 L P +LRLG +YL LP I+QP L RL+ S+GE+AS VLD ++V +A S +++S Sbjct: 65 LLPRILRLGHAYLSGTPLPTIIQPHLDRLSQSVGESASASVLDGAEIVYIARASQMRVIS 124 Query: 141 TTLQPGTRVPAYCTANGRILLANLPPAQLEAILARAQPEAITAHTITDVERLGLEIARAR 200 L G+R+PAYC + GR+LLA L ++ IL + + A T T D E+L E+ R R Sbjct: 125 INLMAGSRLPAYCASMGRVLLAWLDESEARTILEQTELRARTPFTQKDPEKLMEELRRIR 184 Query: 201 VRGYALVDQELELGLRTMAVPVRNFRGEVVAAMNISVHAGRMKLEDMVERCLPAMLKIQV 260 +G+A+ DQELELGLR++AVPV N RG VVAA+NI +++ D+V R LP MLKIQ Sbjct: 185 AQGFAVNDQELELGLRSIAVPVFNHRGAVVAALNIGAPVAHVEVSDLVGRILPEMLKIQS 244 Query: 261 ELGALL 266 EL ++L Sbjct: 245 ELRSML 250 >AGl644 [K] COG1414 Transcriptional regulator Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 269 Score = 228 bits (581), Expect = 1e-59, Method: Compositional matrix adjust. Identities = 119/248 (47%), Positives = 172/248 (69%) Query: 19 KRDLVAGLEKGLQVIEAFDQERSRLTIAEVAQLTGLTRAAARRYLITLTHLGYMRHDNKT 78 +RD++ GL KGL+VIEAF ER RL+I++ A++ GL RA RR L+TL+ LGY +D K Sbjct: 21 ERDMMGGLAKGLRVIEAFSAERPRLSISDAAEIAGLDRATTRRCLLTLSELGYAAYDGKF 80 Query: 79 FSLTPMVLRLGQSYLHSARLPRIVQPLLYRLAYSLGEAASCGVLDHDQLVCVAAVSAGQL 138 F++TP VLRLG L + LP+IVQPLL RL+ +G++ S +LD ++V VA + ++ Sbjct: 81 FTVTPKVLRLGTGCLATMPLPKIVQPLLDRLSEEIGQSTSVSILDEAEIVYVARAAQQRV 140 Query: 139 VSTTLQPGTRVPAYCTANGRILLANLPPAQLEAILARAQPEAITAHTITDVERLGLEIAR 198 +S L PG+R+PAYCT+ GR+LLA P + IL ++ A T TITD++ L EI Sbjct: 141 MSIALMPGSRLPAYCTSMGRVLLAAQPAERRRDILEASRLVARTEKTITDMDALLAEIEV 200 Query: 199 ARVRGYALVDQELELGLRTMAVPVRNFRGEVVAAMNISVHAGRMKLEDMVERCLPAMLKI 258 RGYAL+DQE+E+GLR++AVP++ RG+ VAA+N+ + A +E++VER LPA+L + Sbjct: 201 TGHRGYALIDQEVEIGLRSIAVPLKTVRGQTVAALNVGLAASVASMEELVERYLPALLAV 260 Query: 259 QVELGALL 266 Q EL +L Sbjct: 261 QRELARML 268 >SMb20586 [K] COG1414 Transcriptional regulator Sme Sinorhizobium meliloti Length = 251 Score = 225 bits (574), Expect = 7e-59, Method: Compositional matrix adjust. Identities = 120/242 (49%), Positives = 163/242 (67%) Query: 21 DLVAGLEKGLQVIEAFDQERSRLTIAEVAQLTGLTRAAARRYLITLTHLGYMRHDNKTFS 80 D V+G +GL+VIEAF + + RL+IA+ A++TGL RA RR L+TL+ LGY +D K F+ Sbjct: 5 DFVSGFARGLKVIEAFGEAQPRLSIADAAKITGLDRATVRRSLLTLSQLGYADYDGKFFT 64 Query: 81 LTPMVLRLGQSYLHSARLPRIVQPLLYRLAYSLGEAASCGVLDHDQLVCVAAVSAGQLVS 140 LTP LRLG +YL + LP IVQP L +LA G++AS VLD ++V VA S +++S Sbjct: 65 LTPKTLRLGHAYLSATPLPTIVQPYLDQLAEKAGQSASASVLDGTEIVYVARASQRRVMS 124 Query: 141 TTLQPGTRVPAYCTANGRILLANLPPAQLEAILARAQPEAITAHTITDVERLGLEIARAR 200 L PG+R+PAYC + GR+LLA LP A+ IL R++ +A T T TD E L E+ R R Sbjct: 125 INLTPGSRLPAYCASMGRVLLAALPEAEAREILGRSELKANTPLTRTDPEELLTELRRVR 184 Query: 201 VRGYALVDQELELGLRTMAVPVRNFRGEVVAAMNISVHAGRMKLEDMVERCLPAMLKIQV 260 GYA++DQELELGL ++AVPV N RG+V+AA+NI A + +M ER LP + + Q Sbjct: 185 DEGYAIIDQELELGLCSIAVPVANDRGQVLAALNIGASAAHVPAREMAERFLPLLRETQA 244 Query: 261 EL 262 L Sbjct: 245 AL 246 >Cgl2340 [K] COG1414 Transcriptional regulator Cgl Corynebacterium glutamicum Length = 255 Score = 204 bits (520), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 109/249 (43%), Positives = 157/249 (63%), Gaps = 4/249 (1%) Query: 21 DLVAGLEKGLQVIEAFDQERSRLTIAEVAQLTGLTRAAARRYLITLTHLGYMRHDNKTFS 80 D V +GL VI +F + T++EVA TGL+RA ARR+L TLT LGY +++ F Sbjct: 7 DFVQSFARGLSVIRSFSADNPSQTLSEVASQTGLSRATARRFLHTLTDLGYAVNNDSRFQ 66 Query: 81 LTPMVLRLGQSYLHSARLPRIVQPLLYRLAYSLGEAASCGVLDHDQLVCVAAVSAGQLVS 140 LTP VL LG SYL + LP I QP L L+ +GE++S VLD ++ V V ++++ Sbjct: 67 LTPRVLELGASYLSALSLPAIAQPRLEVLSRQVGESSSMSVLDGTDIIYVCRVPVRRIMT 126 Query: 141 TTLQPGTRVPAYCTANGRILLANLPPAQLEAILARAQPEAITAHTITDVERLGLEIARAR 200 + GTR PAY T+ GRI+LANLP +L+ +LA A PE +T ++T + + EI R Sbjct: 127 VNITIGTRFPAYATSMGRIMLANLPEEELDEMLAAAPPEQLTTRSLTSIASIREEIIATR 186 Query: 201 VRGYALVDQELELGLRTMAVPVRNFRGEVVAAMNISVHAGRMKLEDMVERCLPAMLK--- 257 RG++LVDQELE GLR++A P+ N +GEVVA++N+S + +ED+ + LP +L+ Sbjct: 187 ERGWSLVDQELEPGLRSLAAPITNAQGEVVASINVSTQSASHSVEDIRKLVLPQLLETAQ 246 Query: 258 -IQVELGAL 265 I +L AL Sbjct: 247 AISTDLSAL 255 >mlr4184 [K] COG1414 Transcriptional regulator Mlo Mesorhizobium loti Length = 256 Score = 192 bits (487), Expect = 9e-49, Method: Compositional matrix adjust. Identities = 101/239 (42%), Positives = 149/239 (62%) Query: 19 KRDLVAGLEKGLQVIEAFDQERSRLTIAEVAQLTGLTRAAARRYLITLTHLGYMRHDNKT 78 RD V LE+GL V+E + S +T+ E+A+ GLTRA ARR+L+TL GY D + Sbjct: 7 SRDHVGSLERGLAVMEILARHPSGMTLTEMAEQAGLTRAGARRFLLTLVATGYATQDGRM 66 Query: 79 FSLTPMVLRLGQSYLHSARLPRIVQPLLYRLAYSLGEAASCGVLDHDQLVCVAAVSAGQL 138 FSL+P +L + +++L L P++ +A L EA S +L +V VA + ++ Sbjct: 67 FSLSPRLLAVARTWLGGGSLWSFAAPIMRTVAAQLNEACSAAILSGQDVVYVARIPGRRI 126 Query: 139 VSTTLQPGTRVPAYCTANGRILLANLPPAQLEAILARAQPEAITAHTITDVERLGLEIAR 198 +S +L GTR+PAYCT+ GR+LLA L P +L+ L +A E T TITD+ L I + Sbjct: 127 LSVSLDVGTRLPAYCTSMGRMLLAGLAPEELDEFLHQATIERRTPKTITDIGLLAEAIGK 186 Query: 199 ARVRGYALVDQELELGLRTMAVPVRNFRGEVVAAMNISVHAGRMKLEDMVERCLPAMLK 257 AR G+A+VD+ELELGLR++AVP+R+ G VAA+N+S + R + +M LPA+L+ Sbjct: 187 ARADGFAIVDEELELGLRSIAVPIRDRAGNTVAAINVSTQSARFSVAEMEREILPALLE 245 >RSc2255 [K] COG1414 Transcriptional regulator Rso Ralstonia solanacearum Length = 275 Score = 181 bits (459), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 100/245 (40%), Positives = 148/245 (60%), Gaps = 8/245 (3%) Query: 8 EEPGDADEGPLKRDLVAGLEKGLQVIEAFDQERSRLTIAEVAQLTGLTRAAARRYLITLT 67 E+P D+ V +GL VI AF+ ER T++EVA+ TGLTRA ARR L+TL Sbjct: 21 EKPSDS--------YVQSFARGLSVIRAFNAERPAQTLSEVAEATGLTRAGARRILLTLV 72 Query: 68 HLGYMRHDNKTFSLTPMVLRLGQSYLHSARLPRIVQPLLYRLAYSLGEAASCGVLDHDQL 127 LGY+ + + F LTP +L LG +YL S + +P++ L ++ E+ S VLD ++ Sbjct: 73 SLGYVSFEGRLFRLTPRILDLGFAYLTSMPFWNLAEPVMEELVQTVHESCSASVLDGTEI 132 Query: 128 VCVAAVSAGQLVSTTLQPGTRVPAYCTANGRILLANLPPAQLEAILARAQPEAITAHTIT 187 V V V ++++ L G+R+PA+CT+ GR+LL+ LP +L+ +L + T TIT Sbjct: 133 VYVLRVPTQKIIALNLSVGSRLPAFCTSMGRVLLSGLPEDRLDIVLRESDRRPRTQRTIT 192 Query: 188 DVERLGLEIARARVRGYALVDQELELGLRTMAVPVRNFRGEVVAAMNISVHAGRMKLEDM 247 +V+ L IA R +G+ALVDQELE GL +++ P+RN G+++AAMNIS A R M Sbjct: 193 EVDALKDVIAGVRAQGWALVDQELEEGLISLSTPIRNRAGDIIAAMNISGQANRTSARQM 252 Query: 248 VERCL 252 + L Sbjct: 253 TRQFL 257 >PA0155 [K] COG1414 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 279 Score = 172 bits (436), Expect = 7e-43, Method: Compositional matrix adjust. Identities = 110/264 (41%), Positives = 155/264 (58%), Gaps = 8/264 (3%) Query: 4 ERIDEEPGDADEGPLKRDLVAGLEKGLQVIEAFDQERSRLTIAEVAQLTGLTRAAARRYL 63 +RI+ GD + + L +GL VI AF + + LTIA+++ T + RAA RR L Sbjct: 21 KRIEAFTGDPN-------FMTSLARGLAVIHAFQERKRHLTIAQISHRTEIPRAAVRRCL 73 Query: 64 ITLTHLGYMRHDNKTFSLTPMVLRLGQSYLHSARLPRIVQPLLYRLAYSLGEAASCGVLD 123 TL LGY D +T+SL P VL LG +YL S L QP+L RL+ L EA S L+ Sbjct: 74 HTLMQLGYATTDGRTYSLLPKVLTLGHAYLSSTPLAITAQPILDRLSEQLHEACSMATLE 133 Query: 124 HDQLVCVAAVSAGQ-LVSTTLQPGTRVPAYCTANGRILLANLPPAQLEAILARAQPEAIT 182 D ++ +A + Q L+S L G+R+PAYCT+ GRILLA L L A + +A T Sbjct: 134 GDDVLYIARSATPQRLISVDLNVGSRLPAYCTSMGRILLAALDDDALHAYFGGVEMQAKT 193 Query: 183 AHTITDVERLGLEIARARVRGYALVDQELELGLRTMAVPVRNFRGEVVAAMNISVHAGRM 242 + T+ E L + R +G+ +VDQELE+GLR++AVPVR+ G V+AA+N+ HAGR+ Sbjct: 194 SRTLYTPETLLPCLVEIRRQGWCIVDQELEVGLRSLAVPVRDSAGHVLAALNVGTHAGRV 253 Query: 243 KLEDMVERCLPAMLKIQVELGALL 266 ++ R LP +L+ EL A L Sbjct: 254 SRAELESRFLPLLLEASRELSARL 277 >RSc3411 [K] COG1414 Transcriptional regulator Rso Ralstonia solanacearum Length = 262 Score = 145 bits (366), Expect = 9e-35, Method: Compositional matrix adjust. Identities = 86/235 (36%), Positives = 132/235 (56%), Gaps = 2/235 (0%) Query: 25 GLEKGLQVIEAFDQERSRLTIAEVAQLTGLTRAAARRYLITLTHLGYMRHDNKT--FSLT 82 LEKGL V+ AF+ +R +TIAEVA + G+ +++A+R + TL HLGY+R KT + LT Sbjct: 15 SLEKGLAVLGAFNAQRRTMTIAEVAAVAGINKSSAQRMVYTLEHLGYLRKHPKTRRYQLT 74 Query: 83 PMVLRLGQSYLHSARLPRIVQPLLYRLAYSLGEAASCGVLDHDQLVCVAAVSAGQLVSTT 142 P +++G +YL + L + P L L E + D ++V VA + Q V Sbjct: 75 PAAMKIGFNYLAADTLIDVANPFLAELTKVTTETSCLTEPDQREMVYVARFVSAQFVPVH 134 Query: 143 LQPGTRVPAYCTANGRILLANLPPAQLEAILARAQPEAITAHTITDVERLGLEIARARVR 202 + G+R+P YCTA+GR L+ LP + AI+ ++ A T HT T+V + + AR R Sbjct: 135 MPIGSRIPMYCTASGRAYLSALPEPEARAIVETSERVAHTMHTRTEVADILATLREARQR 194 Query: 203 GYALVDQELELGLRTMAVPVRNFRGEVVAAMNISVHAGRMKLEDMVERCLPAMLK 257 GYA+ +EL LG T+A P+ G + A+++ GR EDM + P +L+ Sbjct: 195 GYAINREELFLGDMTVAAPIVGGNGRPLGAIHLVAPTGRWTAEDMEAKLGPPLLQ 249 >PA3508 [K] COG1414 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 277 Score = 114 bits (284), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 80/242 (33%), Positives = 124/242 (51%), Gaps = 3/242 (1%) Query: 12 DADEGPLKRDLVAGLEKGLQVIEAFDQERSRLTIAEVAQLTGLTRAAARRYLITLTHLGY 71 D + + +V GLE+GL ++ F ++ LT E+A+ L R+ R L TL +G+ Sbjct: 2 DKSDDSQDKYIVPGLERGLLLLCEFSRKDRTLTAPELARRLKLPRSTIFRLLTTLEAMGF 61 Query: 72 MRHDNKTFSLTPMVLRLGQSYLHSARLPRIVQPLLYRLAYSLGEAASCGVLDHDQLVCVA 131 + + + L VLRLG YL S L + QPLL RL + + V D +V VA Sbjct: 62 VTRNGNEYRLGMAVLRLGFEYLASLELTELGQPLLNRLCDEIRYPCNLVVRDGRSIVYVA 121 Query: 132 AVSAGQLVSTTLQPGTRVPAYCTANGRILLANLPPAQLEAILARAQPEAITAHTITDVER 191 VS +S+++ GTR+PA+ T GRILL +L +L + Q E + +T V Sbjct: 122 KVSPSTPLSSSVNVGTRLPAHATVLGRILLQDLSLGELRELYPEEQLEQFSPNTPRSVLE 181 Query: 192 LGLEIARARVRGYALVDQELELGLRTMAVPVRNFRGEVVAAMNISVHAGRM---KLEDMV 248 L + R RG+ + E + T+A PVR+ G V+AAM ++ AG + ++E +V Sbjct: 182 LFDMVQGDRQRGFVQGEGFFEASISTVAAPVRDHSGRVIAAMGATIAAGHIDPERIEGLV 241 Query: 249 ER 250 R Sbjct: 242 SR 243 >DR1156 [K] COG1414 Transcriptional regulator Dra Deinococcus radiodurans Length = 267 Score = 108 bits (271), Expect = 9e-24, Method: Compositional matrix adjust. Identities = 78/243 (32%), Positives = 123/243 (50%), Gaps = 6/243 (2%) Query: 26 LEKGLQVIEAFDQERSRLTIAEVAQLTGLTRAAARRYLITLTHLGYMRHDNKT--FSLTP 83 LE+GL V+ A + R T+ +VA+ GL+ + R L TL GY+ + ++ FS+ Sbjct: 23 LERGLSVLSALAELR-EATLTQVAKKAGLSASTTYRLLETLRQQGYVEWEERSGLFSVGL 81 Query: 84 MVLRLGQSYLHSARLPRIVQPLLYRLAYSLGEAASCGVLDHDQLVCVAAVSAGQLVSTTL 143 ++G ++ L ++ L + E A+ VL ++ V V V A QL+ Sbjct: 82 RAYQVGAAFSERNSLLSAAGAVMQALVEEVNETANLAVLRGNEAVYVHQVEASQLMRMFT 141 Query: 144 QPGTRVPAYCTANGRILLANLPPAQLEAILARAQPEAITAHTITDVERLGLEIARARVRG 203 G P +C+ G++L A LPPA++ + A T H+IT + L E+ R + Sbjct: 142 HIGAAAPLHCSGVGKVLTAWLPPAEVRRKVGDGPFPAYTPHSITTLAALTRELNTVRGQD 201 Query: 204 YALVDQELELGLRTMAVPVRNFRGEVVAAMNISVHAGRM---KLEDMVERCLPAMLKIQV 260 YAL D+E ELG+R +A PVR GEVVA++++S R + DM+ R A +I Sbjct: 202 YALDDEERELGVRCLATPVRAASGEVVASLSVSAPTSRFPKKNIPDMLGRVQAASEQISA 261 Query: 261 ELG 263 LG Sbjct: 262 RLG 264