BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0030.0171.p (216 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc3404 [TK] COG0745 Response regulators consisting of a CheY-li... 243 2e-64 RSp1554 [TK] COG0745 Response regulators consisting of a CheY-li... 206 3e-53 PA4776 [TK] COG0745 Response regulators consisting of a CheY-lik... 191 1e-48 ygiX [TK] COG0745 Response regulators consisting of a CheY-like ... 183 3e-46 ZygiX [TK] COG0745 Response regulators consisting of a CheY-like... 183 3e-46 ECs3907 [TK] COG0745 Response regulators consisting of a CheY-li... 182 4e-46 YPO3507 [TK] COG0745 Response regulators consisting of a CheY-li... 182 5e-46 BMEII1014 [TK] COG0745 Response regulators consisting of a CheY-... 180 2e-45 VCA1105 [TK] COG0745 Response regulators consisting of a CheY-li... 180 3e-45 STM3177 [TK] COG0745 Response regulators consisting of a CheY-li... 179 3e-45 >RSc3404 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Rso Ralstonia solanacearum Length = 221 Score = 243 bits (621), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 137/215 (63%), Positives = 161/215 (74%), Gaps = 1/215 (0%) Query: 1 LVEDDAMIGEEVRCALKDNGYAADWVRAGDAALLALAQQQYDALLLDLGLPGADGLAVLR 60 L+EDD MIG V AL+D YA DWVR G A+ A Q YD LLLDLGLPG DG AVLR Sbjct: 5 LIEDDPMIGAVVEAALRDAAYAVDWVRDGRTAVDVSAHQHYDLLLLDLGLPGQDGHAVLR 64 Query: 61 QLRTH-SLLPVLVITARDGIQDRIGGLDAGADDYLLKPFAIGELLARLRAVLRRRSGAAS 119 LR + +PVL++TARD + +R+ GLD GADDY+LKPF + ELLAR+RAVLRRR GAAS Sbjct: 65 TLRARDNPVPVLILTARDAVDERVRGLDGGADDYVLKPFEMVELLARMRAVLRRRGGAAS 124 Query: 120 DQLSNGQITLDLAAKTACWREGPAVLLSAREFALLCALMGRPGAILSRAELEEKLYGWGE 179 LSNG ++LD A +G V LS REFALL ALM RPGAILSR ELEE++YGWG Sbjct: 125 PVLSNGVLSLDPATHEVRAGDGEPVRLSGREFALLQALMLRPGAILSRGELEERIYGWGH 184 Query: 180 EVESNAVEFLIHSLRRKLDKEAIKNVRGMGWLVQR 214 EV SNAVEFLIH+LR+KL E+IKNVRG+GW+V + Sbjct: 185 EVASNAVEFLIHALRKKLGAESIKNVRGVGWMVSK 219 >RSp1554 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Rso Ralstonia solanacearum Length = 246 Score = 206 bits (524), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 108/224 (48%), Positives = 152/224 (67%), Gaps = 11/224 (4%) Query: 1 LVEDDAMIGEEVRCALKDNGYAADWVRAGDAALLALAQ---------QQYDALLLDLGLP 51 LVEDD MIGE VR L+ +G+A DWVR G+AA+ A+ +D +LLDLGLP Sbjct: 8 LVEDDDMIGEAVRKGLRQDGFAIDWVRDGEAAVQAIGAPGAASEAGGSMFDLMLLDLGLP 67 Query: 52 GADGLAVLRQLRTHSL-LPVLVITARDGIQDRIGGLDAGADDYLLKPFAIGELLARLRAV 110 DGL V+ ++R + LP+L++TARD + DR+ GL+AGADDYL+KPF + EL AR+ A+ Sbjct: 68 KRDGLDVVHEVRRRGITLPILILTARDAVADRVAGLNAGADDYLVKPFDLQELAARMHAL 127 Query: 111 LRRRSGAASDQLSNGQITLDLAAKTACWREGPAVLLSAREFALLCALMGRPGAILSRAEL 170 LRR+ G A + +G++ L+ + R G + LS REFA+L AL+ RPG + S A+L Sbjct: 128 LRRQGGRADPLMRHGEVLLNPVTREVL-RAGMPIKLSGREFAVLHALLSRPGKVWSIAQL 186 Query: 171 EEKLYGWGEEVESNAVEFLIHSLRRKLDKEAIKNVRGMGWLVQR 214 ++ LYGW EEV SN VE IH+LR+KL I+N+RG+G+++ R Sbjct: 187 QDNLYGWDEEVGSNTVEVYIHALRKKLGSHFIQNIRGVGYVIPR 230 >PA4776 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Pae Pseudomonas aeruginosa Length = 221 Score = 191 bits (485), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 104/211 (49%), Positives = 140/211 (66%), Gaps = 2/211 (0%) Query: 1 LVEDDAMIGEEVRCALKDNGYAADWVRAGDAALLALAQQQYDALLLDLGLPGADGLAVLR 60 L EDD ++G+ +R L+ G +WV G AA AL ++D L+LD+GLP GL +LR Sbjct: 5 LAEDDLLLGDGIRAGLRLEGDTVEWVTDGVAAENALVTDEFDLLVLDIGLPRRSGLDILR 64 Query: 61 QLRTHSLL-PVLVITARDGIQDRIGGLDAGADDYLLKPFAIGELLARLRAVLRRRSGAAS 119 LR LL PVL++TARD + DR+ GLD+GADDYL KPF + EL AR+RA+ RR +G A Sbjct: 65 NLRHQGLLTPVLLLTARDKVADRVAGLDSGADDYLTKPFDLDELQARVRALTRRTTGRAL 124 Query: 120 DQLSNGQITLDLAAKTACWREGPAVLLSAREFALLCALMGRPGAILSRAELEEKLYGWGE 179 QL +G++ LD A G AV L+ RE+ALL L+ G +LSR +LE+ LYGW Sbjct: 125 PQLVHGELRLDPATHQVTL-SGQAVELAPREYALLRLLLENSGKVLSRNQLEQSLYGWSG 183 Query: 180 EVESNAVEFLIHSLRRKLDKEAIKNVRGMGW 210 +VESNA+E +H LRRKL + I+ VRG+G+ Sbjct: 184 DVESNAIEVHVHHLRRKLGNQLIRTVRGIGY 214 >ygiX [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Eco Escherichia coli K12 Length = 219 Score = 183 bits (464), Expect = 3e-46, Method: Compositional matrix adjust. Identities = 99/211 (46%), Positives = 134/211 (63%), Gaps = 2/211 (0%) Query: 1 LVEDDAMIGEEVRCALKDNGYAADWVRAGDAALLALAQQQYDALLLDLGLPGADGLAVLR 60 L+EDD +IG+ ++ L G++ DW G AL YDA++LDL LPG DG +LR Sbjct: 5 LIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILR 64 Query: 61 QLRTHSLL-PVLVITARDGIQDRIGGLDAGADDYLLKPFAIGELLARLRAVLRRRSGAAS 119 + R PVL++TARD + +R+ GL GADDYL KPFA+ E+ ARL A++RR +G AS Sbjct: 65 EWREKGQREPVLILTARDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQAS 124 Query: 120 DQLSNGQITLDLAAKTACWREGPAVLLSAREFALLCALMGRPGAILSRAELEEKLYGWGE 179 ++L +G + LD + A G + L +EFALL LM G +LSR +EEKLY W E Sbjct: 125 NELRHGNVMLDPGKRIATL-AGEPLTLKPKEFALLELLMRNAGRVLSRKLIEEKLYTWDE 183 Query: 180 EVESNAVEFLIHSLRRKLDKEAIKNVRGMGW 210 EV SNAVE +H LRRKL + I+ V G+G+ Sbjct: 184 EVTSNAVEVHVHHLRRKLGSDFIRTVHGIGY 214 >ZygiX [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain EcZ Escherichia coli O157:H7 EDL933 Length = 219 Score = 183 bits (464), Expect = 3e-46, Method: Compositional matrix adjust. Identities = 98/211 (46%), Positives = 134/211 (63%), Gaps = 2/211 (0%) Query: 1 LVEDDAMIGEEVRCALKDNGYAADWVRAGDAALLALAQQQYDALLLDLGLPGADGLAVLR 60 L+EDD +IG+ ++ L G++ DW G AL YDA++LDL LPG DG +LR Sbjct: 5 LIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILR 64 Query: 61 QLRTHSLL-PVLVITARDGIQDRIGGLDAGADDYLLKPFAIGELLARLRAVLRRRSGAAS 119 + R PVL++TARD +++R+ GL GADDYL KPFA+ E+ ARL A++RR +G AS Sbjct: 65 EWREKGQREPVLILTARDALEERVXGLRLGADDYLCKPFALIEVAARLEALMRRTNGQAS 124 Query: 120 DQLSNGQITLDLAAKTACWREGPAVLLSAREFALLCALMGRPGAILSRAELEEKLYGWGE 179 ++L +G + LD + A G + L +EFALL LM G +L R +EEKLY W E Sbjct: 125 NELRHGNVMLDPGKRIATL-AGEPLTLKPKEFALLELLMRNAGRVLPRKLIEEKLYTWDE 183 Query: 180 EVESNAVEFLIHSLRRKLDKEAIKNVRGMGW 210 EV SNAVE +H LRRKL + I+ V G+G+ Sbjct: 184 EVTSNAVEVHVHHLRRKLGSDFIRTVHGIGY 214 >ECs3907 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Ecs Escherichia coli O157:H7 Length = 219 Score = 182 bits (463), Expect = 4e-46, Method: Compositional matrix adjust. Identities = 98/211 (46%), Positives = 134/211 (63%), Gaps = 2/211 (0%) Query: 1 LVEDDAMIGEEVRCALKDNGYAADWVRAGDAALLALAQQQYDALLLDLGLPGADGLAVLR 60 L+EDD +IG+ ++ L G++ DW G AL YDA++LDL LPG DG +LR Sbjct: 5 LIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILR 64 Query: 61 QLRTHSLL-PVLVITARDGIQDRIGGLDAGADDYLLKPFAIGELLARLRAVLRRRSGAAS 119 + R PVL++TARD +++R+ GL GADDYL KPFA+ E+ ARL A++RR +G AS Sbjct: 65 EWREKGQREPVLILTARDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQAS 124 Query: 120 DQLSNGQITLDLAAKTACWREGPAVLLSAREFALLCALMGRPGAILSRAELEEKLYGWGE 179 ++L +G + LD + A G + L +EFALL LM G +L R +EEKLY W E Sbjct: 125 NELRHGNVMLDPGKRIATL-AGEPLTLKPKEFALLELLMRNAGRVLPRKLIEEKLYTWDE 183 Query: 180 EVESNAVEFLIHSLRRKLDKEAIKNVRGMGW 210 EV SNAVE +H LRRKL + I+ V G+G+ Sbjct: 184 EVTSNAVEVHVHHLRRKLGSDFIRTVHGIGY 214 >YPO3507 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Ype Yersinia pestis Length = 220 Score = 182 bits (462), Expect = 5e-46, Method: Compositional matrix adjust. Identities = 92/211 (43%), Positives = 137/211 (64%), Gaps = 2/211 (0%) Query: 1 LVEDDAMIGEEVRCALKDNGYAADWVRAGDAALLALAQQQYDALLLDLGLPGADGLAVLR 60 +VEDD ++ + AL GY D A L QY ++LDLGLP DG +LR Sbjct: 5 IVEDDELLQRGIAMALTSEGYVCDCAATAAEAHSLLQTSQYSMIILDLGLPDQDGTLLLR 64 Query: 61 Q-LRTHSLLPVLVITARDGIQDRIGGLDAGADDYLLKPFAIGELLARLRAVLRRRSGAAS 119 Q R H LPVL++TARD ++DR+ GLDAGADDYL+KPFA+ ELLAR+RA++RR G + Sbjct: 65 QWRRQHVTLPVLILTARDALEDRVDGLDAGADDYLVKPFALAELLARVRALIRRYQGQSD 124 Query: 120 DQLSNGQITLDLAAKTACWREGPAVLLSAREFALLCALMGRPGAILSRAELEEKLYGWGE 179 + + ++L+L+ + C +G + ++ +EFA+L L+ R G ++R L++ LY W + Sbjct: 125 NLVQQDDLSLNLSTQQVCL-QGQPLEITPKEFAILSRLIMRAGQTVNRELLQQDLYTWND 183 Query: 180 EVESNAVEFLIHSLRRKLDKEAIKNVRGMGW 210 ++ SN +E IH+LRRKL K+ I+ VRG+G+ Sbjct: 184 DLSSNTLEVHIHNLRRKLGKDRIRTVRGIGY 214 >BMEII1014 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Bme Brucella melitensis Length = 225 Score = 180 bits (457), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 102/211 (48%), Positives = 135/211 (63%), Gaps = 2/211 (0%) Query: 1 LVEDDAMIGEEVRCALKDNGYAADWVRAGDAALLALAQQQYDALLLDLGLPGADGLAVLR 60 L+EDD ++G VR + G+ DWV D A + +YD +LLDL LP GL+ LR Sbjct: 5 LIEDDPILGAAVRDHIAAEGHCVDWVSRLDTAHDYMESARYDLVLLDLMLPDGQGLSFLR 64 Query: 61 QLRTHSL-LPVLVITARDGIQDRIGGLDAGADDYLLKPFAIGELLARLRAVLRRRSGAAS 119 LRT PV+++TA D I DRI GL+AGADDYL KPF + EL ARL AV RR SG + Sbjct: 65 DLRTKGCSTPVIILTALDQISDRIQGLNAGADDYLTKPFDLSELSARLNAVARRYSGNPN 124 Query: 120 DQLSNGQITLDLAAKTACWREGPAVLLSAREFALLCALMGRPGAILSRAELEEKLYGWGE 179 + G + +DLAAK+ R+G A+ L+ARE+ALL A + PG LS+A+LEE LY + Sbjct: 125 PLIEIGGLQIDLAAKSV-MRDGRALCLTAREWALLEAFLQHPGQTLSKAQLEEHLYSFDT 183 Query: 180 EVESNAVEFLIHSLRRKLDKEAIKNVRGMGW 210 EVESN +E + LR+KL I+ VRG+G+ Sbjct: 184 EVESNTMEVHVSRLRKKLGHAIIETVRGIGY 214 >VCA1105 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Vch Vibrio cholerae Length = 218 Score = 180 bits (456), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 98/215 (45%), Positives = 146/215 (67%), Gaps = 2/215 (0%) Query: 1 LVEDDAMIGEEVRCALKDNGYAADWVRAGDAALLALAQQQYDALLLDLGLPGADGLAVLR 60 LVEDD ++GE ++ AL GY DW+ G + AL +Q+ AL+LDL LP DGL VLR Sbjct: 5 LVEDDTLLGESMQVALSRQGYTVDWLERGGGVVTALKTEQFTALILDLTLPDMDGLEVLR 64 Query: 61 QLRTHSL-LPVLVITARDGIQDRIGGLDAGADDYLLKPFAIGELLARLRAVLRRRSGAAS 119 Q+R LPV+++TARD I DR+ GLD GAD+Y+ KPFA+ ELLARLR ++RR SG+A Sbjct: 65 QIRRAGYTLPVMILTARDDISDRVKGLDGGADEYIGKPFALEELLARLRLIIRRSSGSAE 124 Query: 120 DQLSNGQITLDLAAKTACWREGPAVLLSAREFALLCALMGRPGAILSRAELEEKLYGWGE 179 + +S G++ L L +K + A+ L+ E+ +L +LM + G ++S+ L++ L+GW E Sbjct: 125 ELISVGELDLSL-SKQEIYYAQQALKLTRNEYKILASLMTQAGRVMSKELLQQALHGWDE 183 Query: 180 EVESNAVEFLIHSLRRKLDKEAIKNVRGMGWLVQR 214 NA+E IH+LR+KL +KNVRG+G+++++ Sbjct: 184 GSSDNAIEVHIHNLRKKLPDNLVKNVRGVGYMIEK 218 >STM3177 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Sty Salmonella typhimurium LT2 Length = 219 Score = 179 bits (455), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 99/211 (46%), Positives = 133/211 (63%), Gaps = 2/211 (0%) Query: 1 LVEDDAMIGEEVRCALKDNGYAADWVRAGDAALLALAQQQYDALLLDLGLPGADGLAVLR 60 LVEDD +IG+ ++ L G++ DW G AL YDA++LDL LPG DG +LR Sbjct: 5 LVEDDTLIGDGIKAGLSKMGFSVDWFTEGRPGKEALYSAPYDAVILDLTLPGMDGRDILR 64 Query: 61 QLRTHSLL-PVLVITARDGIQDRIGGLDAGADDYLLKPFAIGELLARLRAVLRRRSGAAS 119 + R PVL++TARD + +R+ GL GADDYL KPFA+ E+ ARL A++RR SG AS Sbjct: 65 EWREKGKQEPVLILTARDALAERVEGLRLGADDYLCKPFALIEVAARLEALVRRASGQAS 124 Query: 120 DQLSNGQITLDLAAKTACWREGPAVLLSAREFALLCALMGRPGAILSRAELEEKLYGWGE 179 +L +GQ+TL+ A G + L +EFALL L+ G +L R +EEKLY W + Sbjct: 125 SELRHGQVTLNPGNLVATL-AGEPLALKPKEFALLELLLRNKGRVLPRKLIEEKLYNWDD 183 Query: 180 EVESNAVEFLIHSLRRKLDKEAIKNVRGMGW 210 +V SNAVE +H LRRKL E I+ V G+G+ Sbjct: 184 DVSSNAVEVHVHHLRRKLGSEFIRTVHGIGY 214