BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0030.0157.p (135 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGl595 [IQR] COG1028 Dehydrogenases with different specificities... 122 3e-28 L77482 [IQR] COG1028 Dehydrogenases with different specificities... 93 2e-19 PA1379 [IQR] COG1028 Dehydrogenases with different specificities... 89 3e-18 SMa0326 [IQR] COG1028 Dehydrogenases with different specificitie... 84 7e-17 CAC3335 [IQR] COG1028 Dehydrogenases with different specificitie... 83 1e-16 BS_yusZ [IQR] COG1028 Dehydrogenases with different specificitie... 81 5e-16 L172964 [IQR] COG1028 Dehydrogenases with different specificitie... 80 1e-15 mlr1899 [IQR] COG1028 Dehydrogenases with different specificitie... 77 8e-15 SMc00733 [IQR] COG1028 Dehydrogenases with different specificiti... 77 8e-15 mlr2473 [IQR] COG1028 Dehydrogenases with different specificitie... 76 2e-14 >AGl595 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 249 Score = 122 bits (305), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 70/120 (58%), Positives = 83/120 (69%), Gaps = 1/120 (0%) Query: 2 KTIFITGCSSGFGLEIARYFLQRDWKVIATMRTPRHDLLPA-SPHLRILPLDVADAHSIQ 60 TI ITG SSG+G IA FL R W VIATMR P + LR+LPLDV + SI Sbjct: 3 NTILITGTSSGYGKAIAELFLARGWNVIATMRRPSAARFAGDNGRLRVLPLDVTEEASIA 62 Query: 61 AAVEAAGPVDVLVNNAGIGNLGALEAQPMAQVRELFETNTLGSIAMTQAFIPQMRGNGRG 120 AA+EAAGP+DVLVNNAGIG +GA EA PM+ +R +F+TN+ G +AMTQA IPQMR G Sbjct: 63 AAIEAAGPIDVLVNNAGIGMVGAFEATPMSAIRTIFDTNSFGVMAMTQAVIPQMRKRQSG 122 >L77482 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Lla Lactococcus lactis Length = 277 Score = 92.8 bits (229), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 52/124 (41%), Positives = 70/124 (56%), Gaps = 7/124 (5%) Query: 2 KTIFITGCSSGFGLEIARYFLQRDWKVIATMRTPRHDLLPA-SPHLRILPLDVADAHSIQ 60 K + ITG S+G G E A F +R WKV A R R + +P +++ L LDV + S Q Sbjct: 4 KIVAITGASNGMGFEAAELFAKRGWKVYAGAR--RVEKIPQYENNIKALKLDVTSSESNQ 61 Query: 61 AAV----EAAGPVDVLVNNAGIGNLGALEAQPMAQVRELFETNTLGSIAMTQAFIPQMRG 116 A V + AG +DVL+NNAG G G E PM ++R FETN G++ +TQ +P MR Sbjct: 62 AFVKKILDEAGHIDVLINNAGYGEYGPAEEIPMDKIRNQFETNFFGAVELTQLVLPTMRA 121 Query: 117 NGRG 120 G Sbjct: 122 QNYG 125 >PA1379 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Pae Pseudomonas aeruginosa Length = 277 Score = 88.6 bits (218), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 54/128 (42%), Positives = 73/128 (57%), Gaps = 11/128 (8%) Query: 2 KTIFITGCSSGFGLEIARYFLQRDWKVIATMRTPR-----HDLLPASPHLRILPLDVADA 56 KT+ ITG SSGFG +AR L +V+ T+R+ + P R+L DV D Sbjct: 5 KTLLITGASSGFGQALAREALDAGHRVVGTVRSEEARSALEAVAPGQAFGRLL--DVTDL 62 Query: 57 HSIQAAVEAA----GPVDVLVNNAGIGNLGALEAQPMAQVRELFETNTLGSIAMTQAFIP 112 +I+ V A GP+DVLVN+AG G+ G LE P+A++R FE N G++AM QA +P Sbjct: 63 AAIEPTVAAIERDIGPLDVLVNSAGYGHEGILEESPLAEMRRQFEVNLFGAVAMIQAVLP 122 Query: 113 QMRGNGRG 120 MR RG Sbjct: 123 YMRRRRRG 130 >SMa0326 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Sme Sinorhizobium meliloti Length = 279 Score = 84.0 bits (206), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 51/125 (40%), Positives = 65/125 (52%), Gaps = 7/125 (5%) Query: 2 KTIFITGCSSGFGLEIARYFLQRDWKVIATMRTPRH--DLLPASPHLRILPLDVADAHSI 59 K +TGCS+GFG IA + L+ KV+ T R DL L ILPLDV D Sbjct: 7 KVWLVTGCSTGFGRYIAEHLLEVGEKVVVTARKADKIADLEQKGDAL-ILPLDVIDRDQC 65 Query: 60 QAAVEAA----GPVDVLVNNAGIGNLGALEAQPMAQVRELFETNTLGSIAMTQAFIPQMR 115 Q V+AA G +DVL+NNAGIG GA+E + R LF+ N G+ + +P MR Sbjct: 66 QKVVDAAEAHFGRIDVLINNAGIGFFGAIEETDESNARRLFDVNFFGTANTIHSVLPHMR 125 Query: 116 GNGRG 120 G Sbjct: 126 ARRSG 130 >CAC3335 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Cac Clostridium acetobutylicum Length = 266 Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 48/123 (39%), Positives = 66/123 (53%), Gaps = 10/123 (8%) Query: 4 IFITGCSSGFGLEIARYFLQRDWKVIATMRTPRHDL--LPASPHLRILPLDVADAHSIQA 61 + ITGCS+G G E+ + + + V+AT R DL LPA+ L PLDV S+ Sbjct: 7 VLITGCSTGIGRELCKILYNKGYTVVATARKV-EDLKDLPAALKL---PLDVTKEESVHK 62 Query: 62 AVEAA----GPVDVLVNNAGIGNLGALEAQPMAQVRELFETNTLGSIAMTQAFIPQMRGN 117 A++ +D+LVNNAG GALE ++ V+ +F N G I M QA IP+MR Sbjct: 63 AIKEVMLNFHKIDILVNNAGYSVRGALEEVNVSDVKSMFNVNVFGIINMLQAVIPEMRKR 122 Query: 118 GRG 120 G Sbjct: 123 KTG 125 >BS_yusZ [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Bsu Bacillus subtilis Length = 280 Score = 81.3 bits (199), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 54/128 (42%), Positives = 69/128 (53%), Gaps = 12/128 (9%) Query: 2 KTIFITGCSSGFGLEIARYFLQRDWKVIATMRTPRH-----DLLPA---SPHLRILPLDV 53 K +TG SSGFGL +A L R + VIAT R P +L A S + I LDV Sbjct: 4 KIAIVTGASSGFGL-LAAVKLARSFFVIATSRQPEKAEQLRELAAAHNVSDSIHITALDV 62 Query: 54 ADAHSIQA---AVEAAGPVDVLVNNAGIGNLGALEAQPMAQVRELFETNTLGSIAMTQAF 110 D SI + AV A P+D+LVNNAG G +E PM R+ FETN G I +T+ Sbjct: 63 TDEQSIVSFGKAVSAYAPIDLLVNNAGTAYGGFIEDVPMEHFRQQFETNVFGVIHVTKTV 122 Query: 111 IPQMRGNG 118 +P +R +G Sbjct: 123 LPYIRKHG 130 >L172964 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Lla Lactococcus lactis Length = 281 Score = 80.1 bits (196), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 46/120 (38%), Positives = 64/120 (53%), Gaps = 5/120 (4%) Query: 6 ITGCSSGFGLEIARYFLQRDWKVIATMRT-PRHDLLPASPHLRILPLDVADAHSIQAAVE 64 +TG S+GFG + + +D+KV+AT R LP ++ + LDV SIQ AV Sbjct: 9 VTGSSTGFGRALVEELIAQDYKVVATARQLSTLSELPDKENILKISLDVTKGDSIQKAVA 68 Query: 65 AA----GPVDVLVNNAGIGNLGALEAQPMAQVRELFETNTLGSIAMTQAFIPQMRGNGRG 120 G +DVLVNNAG G G +E + VR++ +TN G+ MT A +P MR G Sbjct: 69 ETIAKFGRIDVLVNNAGFGYFGVMEESDQSAVRKIMDTNFWGANDMTLAVLPYMRKQKSG 128 >mlr1899 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 278 Score = 77.4 bits (189), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 50/126 (39%), Positives = 70/126 (55%), Gaps = 7/126 (5%) Query: 2 KTIFITGCSSGFGLEIARYFLQRDWKVIATMRTPR--HDLLPA-SPHLRILPLDVADAHS 58 KT FITG SSGFG ++ L+R +V AT+R P HDL L + LDV D+ + Sbjct: 3 KTWFITGASSGFGRQLTELLLERGDRVAATVRKPDALHDLATKYGERLWVGILDVTDSSA 62 Query: 59 IQAAVEAA----GPVDVLVNNAGIGNLGALEAQPMAQVRELFETNTLGSIAMTQAFIPQM 114 ++ V A +DV+V+NAG GA E AQ+ +TN +GSI++ +A IP + Sbjct: 63 VRDIVGKAFAELKRIDVVVSNAGYALFGAAEEVADAQIERQIDTNLVGSISVARAVIPDL 122 Query: 115 RGNGRG 120 R G G Sbjct: 123 RQQGGG 128 >SMc00733 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Sme Sinorhizobium meliloti Length = 277 Score = 77.4 bits (189), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 49/124 (39%), Positives = 62/124 (50%), Gaps = 7/124 (5%) Query: 3 TIFITGCSSGFGLEIARYFLQRD-WKVIATMRTPRHDLLPASPHLRILPLDVADAHSIQA 61 TI +TGCSSG G AR LQRD W+V AT+R P + + +D +I A Sbjct: 6 TIIVTGCSSGIGAYCAR-ALQRDGWRVFATVRRPEDQAPLEAEGIETFIMDYTRPETIAA 64 Query: 62 AVEA-----AGPVDVLVNNAGIGNLGALEAQPMAQVRELFETNTLGSIAMTQAFIPQMRG 116 VEA G +D L NN G GA+E P +R ETN +G +T+ IP MR Sbjct: 65 LVEAVMALSGGRIDALFNNGAYGQAGAVEDLPTEALRLQLETNVIGWHDLTRRVIPAMRA 124 Query: 117 NGRG 120 G G Sbjct: 125 RGHG 128 >mlr2473 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 276 Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 48/121 (39%), Positives = 71/121 (58%), Gaps = 7/121 (5%) Query: 2 KTIFITGCSSGFGLEIARYFLQRDWKVIATMRTPRH--DLLP-ASPHLRILPLDVADAHS 58 +T FITG SSGFG + L R +V AT+R P+ DL L I L++ D+ + Sbjct: 3 RTWFITGTSSGFGRLLTDRLLARGDRVAATVRRPQALADLKALHGDRLWIASLEMTDSDA 62 Query: 59 IQAAVEAA----GPVDVLVNNAGIGNLGALEAQPMAQVRELFETNTLGSIAMTQAFIPQM 114 I+A V+ A G +DV+V+NAG G GA E +Q+R+L +TN +GSI + + +P + Sbjct: 63 IRATVDKAFGELGRIDVIVSNAGYGLFGAAEELEDSQIRDLIDTNLIGSIQLIRVALPHL 122 Query: 115 R 115 R Sbjct: 123 R 123