BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0030.0136.p (447 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMb21486 [GEPR] COG0477 Permeases of the major facilitator super... 513 e-145 CC1774 [GEPR] COG0477 Permeases of the major facilitator superfa... 479 e-135 AGc231 [GEPR] COG0477 Permeases of the major facilitator superfa... 440 e-123 mll6844 [GEPR] COG0477 Permeases of the major facilitator superf... 438 e-122 SMc01869 [GEPR] COG0477 Permeases of the major facilitator super... 269 1e-71 AGc3790 [GEPR] COG0477 Permeases of the major facilitator superf... 269 1e-71 BMEII0579 [GEPR] COG0477 Permeases of the major facilitator supe... 238 3e-62 PA3749 [GEPR] COG0477 Permeases of the major facilitator superfa... 205 2e-52 HI0418 [GEPR] COG0477 Permeases of the major facilitator superfa... 204 4e-52 STM3609 [GEPR] COG0477 Permeases of the major facilitator superf... 203 5e-52 >SMb21486 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 431 Score = 513 bits (1320), Expect = e-145, Method: Compositional matrix adjust. Identities = 253/423 (59%), Positives = 327/423 (77%), Gaps = 1/423 (0%) Query: 26 HDHGKIEPGEIAVGVVIGRASEYFDFFVYALASVLVFPAVFFPNEP-KLEGTLYAFVIFA 84 HD + G IA+GVVIGRA+E+FDFFVY +ASV+VFP +FFP P +L TLY+F IF+ Sbjct: 9 HDDTPVSAGNIAIGVVIGRAAEFFDFFVYGIASVVVFPQLFFPFAPDRLTATLYSFAIFS 68 Query: 85 FAFLARPIGTTIFMAIQKHYGREVKLTLALFMLGFSTAGIALLPTFEHIGVWAIILLSLL 144 AF+ARP+G+ +FMAI + YGR VKLT+ALF+LG STA IA LP + +G W+I+LL++ Sbjct: 69 LAFVARPVGSLVFMAIDRTYGRGVKLTIALFLLGGSTASIAFLPGYATLGAWSIVLLAVF 128 Query: 145 RVGQGLALGGAWDGLPSLLAMNAPQHKRGWYAALGQLGAPLGFVVAASLFAYMLSSLTTA 204 R+GQG ALGGAWDGL SLLA+NAPQH RGWYA + QLGAPLGF++A++LFAY L S++ A Sbjct: 129 RLGQGFALGGAWDGLASLLALNAPQHHRGWYAMIPQLGAPLGFMLASALFAYFLVSISKA 188 Query: 205 DFLEWGWRYPFYVAFAINVVALFSRLRLVSAPEYAKLLDERELEPAGVVELATTQGRNII 264 DFL WGWRYPF+VAFAINVVALF+RLRLV E+ LLD EL+ A V E+ G N++ Sbjct: 189 DFLAWGWRYPFFVAFAINVVALFTRLRLVMTKEFGTLLDLHELQAAPVTEVLRANGGNVL 248 Query: 265 IGALAALASYALFHLVTVFPLSWIKLYSLREATDFLVVQIWGGLIMAVGIVISGLIADRF 324 +GA LAS+ALFHLVTVFPLSW+++Y+ A+ FL+VQ G + + I+ SGLIADR Sbjct: 249 VGAFVPLASFALFHLVTVFPLSWVEIYTDHGASSFLMVQFLGAVCGILAIIASGLIADRI 308 Query: 325 GRRNTLGSMALLIAILSAFVPTLMNGGEAGQNTFILIGFALLGLSYGQAAGAVTANFKAR 384 GRRN LG A+LIAI S P L+ G G++ F+++GF +LGLS+GQAAGAV + F Sbjct: 309 GRRNHLGICAVLIAIFSFVAPMLLQAGATGRDVFVIVGFTILGLSFGQAAGAVASRFGKA 368 Query: 385 YRYTGAALTSDLAWLVGAGFAPLVALGLSAHFGMAYVSFYLLSGAVGSLAALSLNRALEA 444 YRYTGAALTSDL+WL+GAGFAPLVALGL++ FG+A+ +YLLSGA+ ++ AL ++ LE Sbjct: 369 YRYTGAALTSDLSWLIGAGFAPLVALGLTSRFGLAFAGYYLLSGALCTILALVFSKKLEI 428 Query: 445 RDD 447 ++ Sbjct: 429 DNE 431 >CC1774 [GEPR] COG0477 Permeases of the major facilitator superfamily Ccr Caulobacter vibrioides Length = 446 Score = 479 bits (1232), Expect = e-135, Method: Compositional matrix adjust. Identities = 241/421 (57%), Positives = 318/421 (75%), Gaps = 1/421 (0%) Query: 27 DHGKIEPGEIAVGVVIGRASEYFDFFVYALASVLVFPAVFFPNEPKLEGTLYAFVIFAFA 86 D + PGEIA+GVVIGR SE+FDFFVYA+ASVLVFP + FP +L G + AF +FA A Sbjct: 23 DDKGVRPGEIALGVVIGRTSEFFDFFVYAIASVLVFPQLVFPFVDRLTGVMLAFGLFALA 82 Query: 87 FLARPIGTTIFMAIQKHYGREVKLTLALFMLGFSTAGIALLPTFEHIGVWAIILLSLLRV 146 F+ARP G+ IF AI + YGR VKLT+ALF+LG STA I++LP+F +G AI L+ R+ Sbjct: 83 FIARPFGSVIFGAIDQRYGRGVKLTIALFLLGGSTAVISMLPSFAAVGPIAIWALAACRI 142 Query: 147 GQGLALGGAWDGLPSLLAMNAPQHKRGWYAALGQLGAPLGFVVAASLFAYMLSSLTTADF 206 GQGLAL GAWDG+ SLLA+NAP++KRGWYA + QLGAP GF++A+ LFAY +++L ADF Sbjct: 143 GQGLALAGAWDGMASLLALNAPENKRGWYAMIPQLGAPFGFMLASGLFAYFVATLAPADF 202 Query: 207 LEWGWRYPFYVAFAINVVALFSRLRLVSAPEYAKLLDERELEPAGVVELATTQGRNIIIG 266 L+WGWRYPF+ AFAINVVALF+RLR+V+ E+ L ++REL P V L +G N++IG Sbjct: 203 LDWGWRYPFFAAFAINVVALFARLRIVATEEFGALFEKRELRPTRVASLLRAEGGNVLIG 262 Query: 267 ALAALASYALFHLVTVFPLSWIKLY-SLREATDFLVVQIWGGLIMAVGIVISGLIADRFG 325 A A LA++A+FHLVTVFPLSW+ L+ ++A +FL ++++G L+ GI+ SG IADR Sbjct: 263 AFAPLATFAMFHLVTVFPLSWVVLHGDAQQALNFLRIELFGALVGVGGILASGWIADRIT 322 Query: 326 RRNTLGSMALLIAILSAFVPTLMNGGEAGQNTFILIGFALLGLSYGQAAGAVTANFKARY 385 R+N L ALLI S P L++GG GQ +++IGFA+LGLS+GQAAGAV++ F RY Sbjct: 323 RQNQLALSALLIGAFSLLAPRLLDGGATGQTAYVVIGFAILGLSFGQAAGAVSSGFSKRY 382 Query: 386 RYTGAALTSDLAWLVGAGFAPLVALGLSAHFGMAYVSFYLLSGAVGSLAALSLNRALEAR 445 RYTGAALTSDL+WL+GAGFAPL ALGL++ +G+ + YL SGA+ +L AL+++R R Sbjct: 383 RYTGAALTSDLSWLIGAGFAPLAALGLASLWGLPAIGLYLASGALATLLALTIDRTRRRR 442 Query: 446 D 446 Sbjct: 443 Q 443 >AGc231 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 440 Score = 440 bits (1132), Expect = e-123, Method: Compositional matrix adjust. Identities = 216/418 (51%), Positives = 296/418 (70%) Query: 30 KIEPGEIAVGVVIGRASEYFDFFVYALASVLVFPAVFFPNEPKLEGTLYAFVIFAFAFLA 89 ++P I + V++ R +E+FDFF+YA+AS LVFP VFF L TLY+F +F+ AF+A Sbjct: 23 SVDPDRITIAVILARMTEFFDFFIYAIASALVFPHVFFSFVDPLTATLYSFAVFSLAFIA 82 Query: 90 RPIGTTIFMAIQKHYGREVKLTLALFMLGFSTAGIALLPTFEHIGVWAIILLSLLRVGQG 149 RPIG+ IF+ I + +GR VKL ALF L ST I+ LP+++ G+ A LL+ R+GQG Sbjct: 83 RPIGSLIFLQIDRKFGRAVKLMAALFTLCGSTMAISFLPSYDEAGMLAPCLLAAFRIGQG 142 Query: 150 LALGGAWDGLPSLLAMNAPQHKRGWYAALGQLGAPLGFVVAASLFAYMLSSLTTADFLEW 209 L LGGAWDGL SLLAMNAPQ +RGWYA + Q+GA +GF +A++ F ++ L+ A+FL W Sbjct: 143 LGLGGAWDGLVSLLAMNAPQKQRGWYAMMPQIGAAMGFGLASAFFIVFVTQLSNAEFLAW 202 Query: 210 GWRYPFYVAFAINVVALFSRLRLVSAPEYAKLLDERELEPAGVVELATTQGRNIIIGALA 269 GWR+PF+VA A+NV+ALF+RLR++ PE+ +L++ ELEP + + +Q ++ GA Sbjct: 203 GWRFPFFVALALNVLALFARLRMIVTPEFQAMLEQHELEPRPMFRMLRSQFPVVLTGAFV 262 Query: 270 ALASYALFHLVTVFPLSWIKLYSLREATDFLVVQIWGGLIMAVGIVISGLIADRFGRRNT 329 LAS+ALFHLVTVFPLSW+ L + + +DFL VQ +I IV+SG++ADR GRR Sbjct: 263 PLASFALFHLVTVFPLSWVSLNTSQRVSDFLFVQFVSAIICGGMIVVSGILADRIGRRKL 322 Query: 330 LGSMALLIAILSAFVPTLMNGGEAGQNTFILIGFALLGLSYGQAAGAVTANFKARYRYTG 389 L A LI + S P L++ G+ G+ F+LIGF+LLGLS+GQA GA+ + F YRYTG Sbjct: 323 LAIAAALIGLFSLVAPVLLSSGDIGRYLFVLIGFSLLGLSFGQAGGALASRFSREYRYTG 382 Query: 390 AALTSDLAWLVGAGFAPLVALGLSAHFGMAYVSFYLLSGAVGSLAALSLNRALEARDD 447 A+LTSD++WL+GAGFAPLVALG S+ FG+ V YL+SGAV +L AL +R LE + Sbjct: 383 ASLTSDISWLIGAGFAPLVALGFSSKFGLFAVGIYLMSGAVCTLVALWFSRTLEMPSE 440 >mll6844 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 411 Score = 438 bits (1126), Expect = e-122, Method: Compositional matrix adjust. Identities = 225/407 (55%), Positives = 300/407 (73%) Query: 40 VVIGRASEYFDFFVYALASVLVFPAVFFPNEPKLEGTLYAFVIFAFAFLARPIGTTIFMA 99 +++GR SE+FDFFVYA+ASV+VFP + FP L GTLY+F IFA AF+ARP G+ +FMA Sbjct: 1 MIVGRTSEFFDFFVYAIASVIVFPKLVFPTHDPLVGTLYSFCIFALAFVARPFGSVLFMA 60 Query: 100 IQKHYGREVKLTLALFMLGFSTAGIALLPTFEHIGVWAIILLSLLRVGQGLALGGAWDGL 159 I + YGR KLT+ALF+LG ST IA LP + IG A+ LL+L R+GQGLALGG WDGL Sbjct: 61 IDRAYGRGAKLTIALFLLGTSTVAIAFLPAYGDIGAVAVWLLALARIGQGLALGGTWDGL 120 Query: 160 PSLLAMNAPQHKRGWYAALGQLGAPLGFVVAASLFAYMLSSLTTADFLEWGWRYPFYVAF 219 PSLLA+NAPQ++RG+YA + QLGAP+G +VA+SLFA+ +++L+ DF WGWRYPF+VAF Sbjct: 121 PSLLALNAPQNRRGFYAMIPQLGAPIGLIVASSLFAFFVANLSADDFFSWGWRYPFFVAF 180 Query: 220 AINVVALFSRLRLVSAPEYAKLLDERELEPAGVVELATTQGRNIIIGALAALASYALFHL 279 AINVVALF+RLR+V PE++KL + +L+P + + +G N++IGA A LAS+ALFH+ Sbjct: 181 AINVVALFARLRIVVTPEFSKLYESGDLQPTRIRDTIRAEGHNVVIGAFAPLASFALFHM 240 Query: 280 VTVFPLSWIKLYSLREATDFLVVQIWGGLIMAVGIVISGLIADRFGRRNTLGSMALLIAI 339 VTVFPLSW+ L++ FL+++ L IV SG +ADR GRR LG A+ IA Sbjct: 241 VTVFPLSWVFLFTNEGPARFLMIEAVSALFGIAAIVASGPLADRVGRRALLGGSAIAIAT 300 Query: 340 LSAFVPTLMNGGEAGQNTFILIGFALLGLSYGQAAGAVTANFKARYRYTGAALTSDLAWL 399 S F P L++GG G+ F+++GF LLGLS+GQ++G V ++F +YRYTG+A+TSDLAW+ Sbjct: 301 FSGFAPQLLDGGAVGEALFMVLGFILLGLSFGQSSGVVASSFSRQYRYTGSAITSDLAWM 360 Query: 400 VGAGFAPLVALGLSAHFGMAYVSFYLLSGAVGSLAALSLNRALEARD 446 GAGFAPL AL L+ +FG+ YLLSGA +L AL ++ A D Sbjct: 361 FGAGFAPLAALLLAGNFGLIAAGAYLLSGAACTLLALWIDGRRPAAD 407 >SMc01869 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 436 Score = 269 bits (687), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 164/420 (39%), Positives = 240/420 (57%), Gaps = 4/420 (0%) Query: 26 HDHGKIEPGEIAVGVVIGRASEYFDFFVYALASVLVFPAVFFPNEPKLEGTLYAFVIFAF 85 H P + ++G E+FDF+VYA A+V++FP +FFP L + F+ Sbjct: 16 HRQAVNSPARVLFASLVGTTIEFFDFYVYATAAVIIFPHLFFPAADPTSAMLQSLATFSI 75 Query: 86 AFLARPIGTTIFMAIQKHYGREVKLTLALFMLGFSTAGIALLPTFEHIGVWAIILLSLLR 145 AF ARP+G IF GR+ L AL +G ST I LLPT+ IGV A +LL+L R Sbjct: 76 AFFARPLGAVIFGHFGDRIGRKATLVAALMTMGISTVVIGLLPTYSTIGVVAPLLLALCR 135 Query: 146 VGQGLALGGAWDGLPSLLAMNAPQHKRGWYAALGQLGAPLGFVVAASLFAYMLSSLTTAD 205 GQGL LGG W G L NAP+ KR WYA QLGAP+GF+++A F + ++ Sbjct: 136 FGQGLGLGGEWGGAVLLATENAPEGKRSWYAMFPQLGAPIGFILSAGTFLILGEVMSEEA 195 Query: 206 FLEWGWRYPFYVAFAINVVALFSRLRLVSAPEYAKLLDERELEPAGVVELATTQGRNIII 265 FL WGWR PF + + +V L+ RL++ PE+ K +D+ E V + + R++++ Sbjct: 196 FLAWGWRVPFIASVLLVIVGLYVRLKITETPEFQKAIDKHERVEVPVAAIFRSHKRSLVL 255 Query: 266 GALAALASYALFHLVTVFPLSW--IKLYSLREATDFLVVQIWGGLIMAVGIVISGLIADR 323 G ALA++ LF+L+TVF LSW KL RE FL+VQ+ G + + I +SG+++DR Sbjct: 256 GTFVALATFVLFYLMTVFSLSWGTTKLGYSRE--QFLLVQMTGVVFFGLMIPVSGILSDR 313 Query: 324 FGRRNTLGSMALLIAILSAFVPTLMNGGEAGQNTFILIGFALLGLSYGQAAGAVTANFKA 383 FGRR L + I + F+ L++ G G F ++G L+GL+YG A+ A F Sbjct: 314 FGRRLVLVLTTIGIGVFGLFMAPLLSSGLGGAFVFSIVGLGLMGLTYGPIGAALAAPFPT 373 Query: 384 RYRYTGAALTSDLAWLVGAGFAPLVALGLSAHFGMAYVSFYLLSGAVGSLAALSLNRALE 443 RYTGA++T +LA + GA AP +A L+ ++ + +V +YLL+ A +L L L+ E Sbjct: 374 AVRYTGASMTFNLAGIFGASLAPYIATWLATNYSLGHVGYYLLAAASITLVCLLLSNEEE 433 >AGc3790 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 434 Score = 269 bits (687), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 159/426 (37%), Positives = 241/426 (56%), Gaps = 2/426 (0%) Query: 19 STHPSTSHDHGKIEPGEIAVGVVIGRASEYFDFFVYALASVLVFPAVFFPNEPKLEGTLY 78 S+ S+ P + ++G E+FDF+VYA A+VLVFPA+FFPN L Sbjct: 9 SSTAGNSNAVKTNSPARVLTASLVGTTIEFFDFYVYATAAVLVFPALFFPNSDPTTALLA 68 Query: 79 AFVIFAFAFLARPIGTTIFMAIQKHYGREVKLTLALFMLGFSTAGIALLPTFEHIGVWAI 138 +F F+ AF ARP+G +F GR+ L AL +G ST I LLPT+E GV A Sbjct: 69 SFATFSIAFFARPLGAVVFGHYGDRVGRKATLVAALLTMGVSTVVIGLLPTYETAGVLAP 128 Query: 139 ILLSLLRVGQGLALGGAWDGLPSLLAMNAPQHKRGWYAALGQLGAPLGFVVAASLFAYML 198 +LL+L R GQG LGG W G L NAP KR WY QLGAP+G +++ +F +L Sbjct: 129 LLLALCRFGQGFGLGGEWGGAVLLATENAPPGKRSWYGMFPQLGAPVGLFLSSGVFWILL 188 Query: 199 SSLTTADFLEWGWRYPFYVAFAINVVALFSRLRLVSAPEYAKLLDERELEPAGVVELATT 258 ++ L WGWR PF + + V ++ RL + P++ K +++ E + EL + Sbjct: 189 HFMSQEALLSWGWRIPFVASIILIAVGMWVRLSITETPDFQKAIEKEERVAVPIAELFRS 248 Query: 259 QGRNIIIGALAALASYALFHLVTVFPLSW-IKLYSLREATDFLVVQIWGGLIMAVGIVIS 317 R++++G ALA++ LF++ T + LS+ +K+ + D L VQI G ++ + I ++ Sbjct: 249 HKRSLVLGTFVALATFVLFYIGTAYLLSYNVKVLKI-PFLDALEVQILGSIVFGIFIPVA 307 Query: 318 GLIADRFGRRNTLGSMALLIAILSAFVPTLMNGGEAGQNTFILIGFALLGLSYGQAAGAV 377 G +A++FGRR L +LI + S +P+LM GGE F + L+G++YG A+ Sbjct: 308 GKLAEKFGRREVLIVTTILIGLFSFLLPSLMTGGEGSIFVFAALAMMLMGMTYGLIGTAL 367 Query: 378 TANFKARYRYTGAALTSDLAWLVGAGFAPLVALGLSAHFGMAYVSFYLLSGAVGSLAALS 437 A F R RYTG+++T ++A + GA AP +A L ++GM YV +YL A+ +LA + Sbjct: 368 AAPFPTRVRYTGSSITFNMAGIFGASLAPYIATWLQVNYGMGYVGYYLCISALITLACIF 427 Query: 438 LNRALE 443 L+R E Sbjct: 428 LSRKDE 433 >BMEII0579 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 426 Score = 238 bits (606), Expect = 3e-62, Method: Compositional matrix adjust. Identities = 153/393 (38%), Positives = 223/393 (56%) Query: 41 VIGRASEYFDFFVYALASVLVFPAVFFPNEPKLEGTLYAFVIFAFAFLARPIGTTIFMAI 100 +IG E+FDF++YA A+V+VFP +FFP L +F FA AF ARP+G IF Sbjct: 22 MIGTTIEFFDFYIYATAAVIVFPYLFFPASDGNSALLQSFATFAIAFFARPVGAAIFGHF 81 Query: 101 QKHYGREVKLTLALFMLGFSTAGIALLPTFEHIGVWAIILLSLLRVGQGLALGGAWDGLP 160 GR+ L AL +G ST I LPT+ IGV A +LL+L R+GQGL LGG W G Sbjct: 82 GDKIGRKATLVAALMTMGLSTVAIGFLPTYASIGVAAPLLLALCRLGQGLGLGGEWGGAV 141 Query: 161 SLLAMNAPQHKRGWYAALGQLGAPLGFVVAASLFAYMLSSLTTADFLEWGWRYPFYVAFA 220 L NAP+ KR WY QLGAP GF++A +F + ++T F +GWR PF + Sbjct: 142 LLATENAPEGKRTWYGMFPQLGAPAGFILATGIFLLLAETMTEEQFFAYGWRVPFIASAI 201 Query: 221 INVVALFSRLRLVSAPEYAKLLDERELEPAGVVELATTQGRNIIIGALAALASYALFHLV 280 + V LF RLR+ PE+ K +D+ E +L N+ +G + +A++ LF+L+ Sbjct: 202 LVAVGLFIRLRIAETPEFQKAIDKAERVAVPAAQLFRHHKMNLFLGTIGTMATFVLFYLM 261 Query: 281 TVFPLSWIKLYSLREATDFLVVQIWGGLIMAVGIVISGLIADRFGRRNTLGSMALLIAIL 340 TVF L W +FLV+Q+ G + + I +S L++DR+G R + + +LI + Sbjct: 262 TVFSLGWGTRALGYSREEFLVLQMIGVIFFGLTIPLSALLSDRYGMRTIMVIVTVLIGLY 321 Query: 341 SAFVPTLMNGGEAGQNTFILIGFALLGLSYGQAAGAVTANFKARYRYTGAALTSDLAWLV 400 + L G AG F++IGF L+G++YG + F RYTGA+L +LA ++ Sbjct: 322 GFIMAPLFAAGTAGVLGFLIIGFGLMGMTYGPIGAVLAEPFPTSVRYTGASLAFNLAGIL 381 Query: 401 GAGFAPLVALGLSAHFGMAYVSFYLLSGAVGSL 433 GA AP +A L+ +G AYV +Y+++ A+ SL Sbjct: 382 GASLAPYIATWLATDYGFAYVGYYMVAAAIISL 414 >PA3749 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 437 Score = 205 bits (522), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 150/384 (39%), Positives = 206/384 (53%), Gaps = 11/384 (2%) Query: 35 EIAVGVVIGRASEYFDFFVYALASVLVFPAVFFPNEPKLEGTLYAFVIFAFAFLARPIGT 94 +AV IG A E++DF+VYA A+ LV VFFP L AF+ F AFLARP+G+ Sbjct: 20 RVAVASFIGTAIEFYDFYVYATAAALVIGPVFFPQTSGTAQMLSAFLTFGIAFLARPLGS 79 Query: 95 TIFMAIQKHYGREVKLTLALFMLGFSTAGIALLPTFEHIGVWAIILLSLLRVGQGLALGG 154 +F GR+ L +L ++G ST I +LP ++ IG WA +LL +LR GQGL LGG Sbjct: 80 ALFGHFGDRIGRKSTLVASLLLMGVSTTLIGVLPGYDSIGYWAPLLLCVLRFGQGLGLGG 139 Query: 155 AWDGLPSLLAMNAPQHKRGWYAALGQLGAPLGFVVAASLFAYMLSSLTTADFLEWGWRYP 214 W G L NAP KR W+ QLG +GF+ A LF + L+ F EWGWR P Sbjct: 140 EWGGAALLATENAPAGKRAWFGMFPQLGPSIGFLAANGLFLALAMLLSEEQFREWGWRIP 199 Query: 215 FYVAFAINVVALFSRLRLVSAPEYAKLLDERELEPAGVVELATTQGRNIIIGALAALASY 274 F ++ A+ VV L+ RL+L P +AK + + E + EL R ++GALA + Y Sbjct: 200 FLLSAALVVVGLYVRLKLAETPVFAKAMAKHERVRLPIAELFAQHWRPTLLGALAMVVCY 259 Query: 275 ALFHLVTVFPLSW--IKLYSLREATDFLVVQIWGGLIMAVGIVISGLIADRFGRRNT--L 330 ALF++ TVF LS+ L RE +FL + L MA +S ++DRFGR+ L Sbjct: 260 ALFYISTVFSLSYGVASLGFSRE--EFLGLLCLAVLFMAAATPLSAWLSDRFGRKPVLLL 317 Query: 331 GSMALLIAILSAFV--PTLMNGGEAGQNTFILIGFALLGLSYGQAAGAVTANFKARYRYT 388 GS+A AI S F P L G F+ I L+G+++ + F RYT Sbjct: 318 GSLA---AIASGFAMEPLLSQGSTFSVALFLCIELFLMGVTFAPMGALLPEIFPTHVRYT 374 Query: 389 GAALTSDLAWLVGAGFAPLVALGL 412 GA+ +L ++GA AP +A L Sbjct: 375 GASAAYNLGGILGASVAPYIAQKL 398 >HI0418 [GEPR] COG0477 Permeases of the major facilitator superfamily Hin Haemophilus influenzae Length = 447 Score = 204 bits (518), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 150/432 (34%), Positives = 224/432 (51%), Gaps = 12/432 (2%) Query: 17 PHSTHPSTSHDHGKIEPGEIAVGVVIGRASEYFDFFVYALASVLVFPAVFFPNEPKLEGT 76 P H + + ++A ++G A EYFD ++YA+A+VLVF FF L G Sbjct: 4 PQQKHYGRQVMNTQNSLKQVATATMVGTAIEYFDNYIYAMAAVLVFNHQFFHAVDPLSGQ 63 Query: 77 LYAFVIFAFAFLARPIGTTIFMAIQKHYGREVKLTLALFMLGFSTAGIALLPTFEHIGVW 136 + A A F+ARP+G +F +GR+ ++L ++G ST I LLPT++ IG+W Sbjct: 64 IAALSTLALTFIARPLGAILFGHFGDRFGRKNTFVMSLLLMGISTVVIGLLPTYDSIGIW 123 Query: 137 AIILLSLLRVGQGLALGGAWDGLPSLLAMNAPQHKRGWYAALGQLGAPLGFVVAASLFAY 196 A ILL L R+GQG+ LGG W G + NAP+ KRGWY QLGAPLG ++A +F Sbjct: 124 ATILLCLCRIGQGIGLGGEWGGAALVAVENAPEGKRGWYGTFPQLGAPLGLLLANGVFLG 183 Query: 197 MLSSLTTADFLEWGWRYPFYVAFAINVVALFSRLRLVSAPEYAKLLDERELEPAGVVELA 256 + + EW WR PF + + + L+ RL+L AP + L++ + + ++E+ Sbjct: 184 ITAIFGQEAMTEWAWRIPFLSSVILVAIGLYVRLKLTEAPIFLAALNKPKPKRLPMLEVV 243 Query: 257 TTQGRNIIIGALAALASYALFHLVTVFPLSWIKLYSLREATDFLV-----VQIWGGLIM- 310 TT + +G L +A Y LF+++ F + K + + QI+ L+M Sbjct: 244 TTHFKPFFLGMLVCIAGYVLFYIMIAFSQIYAKSAPTVSEAGYAMGLGFSPQIFTALLMA 303 Query: 311 -----AVGIVISGLIADRFGRRNTLGSMALLIAILSAFVPT-LMNGGEAGQNTFILIGFA 364 A+ I SG D+ GRR L + +AI +P L NG F+ IG Sbjct: 304 SAVSLAITIAASGKYIDKIGRRTWLIWTTVGVAIFGLSLPLFLENGTTTSLFWFLFIGMG 363 Query: 365 LLGLSYGQAAGAVTANFKARYRYTGAALTSDLAWLVGAGFAPLVALGLSAHFGMAYVSFY 424 L+G+ YG A + F RY+GA+LT ++A L GA A ++AL L+AH+G+ V Y Sbjct: 364 LIGMGYGPLASFLPELFPTHARYSGASLTYNIAGLFGASVAAIIALPLNAHYGLKGVGIY 423 Query: 425 LLSGAVGSLAAL 436 L AV SL L Sbjct: 424 LTLNAVLSLVGL 435 >STM3609 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 440 Score = 203 bits (517), Expect = 5e-52, Method: Compositional matrix adjust. Identities = 155/423 (36%), Positives = 235/423 (55%), Gaps = 17/423 (4%) Query: 18 HSTHPSTSHDHGKI---EPGEIAVGVVIGRASEYFDFFVYALASVLVFPAVFFPNEPKLE 74 +T + H+ + ++ + +IG A E+FDF++YA A+V+VFP +FFP Sbjct: 2 QATATTLDHEQEHVPVNSRNKVVIASLIGTAIEFFDFYIYATAAVIVFPLIFFPQGDPTA 61 Query: 75 GTLYAFVIFAFAFLARPIGTTIFMAIQKHYGREVKLTLALFMLGFSTAGIALLPTFEHIG 134 TL + FA AF+ARPIG+ +F GR+V L +L +G ST I LLP + IG Sbjct: 62 ATLQSLATFAIAFVARPIGSALFGHFGDRVGRKVTLVASLLTMGISTVIIGLLPGYATIG 121 Query: 135 VWAIILLSLLRVGQGLALGGAWDGLPSLLAMNAPQHKRGWYAALGQLGAPLGFVVAASLF 194 ++A +LL+L R GQGL LGG W G L NAP KR Y + QLGAP+GF A F Sbjct: 122 IFAPLLLALARFGQGLGLGGEWGGAALLATENAPPRKRALYGSFPQLGAPIGFFFANGTF 181 Query: 195 AYMLSSLTTADFLEWGWRYPFYVAFAINVVALFSRLRLVSAPEYAKLLDERELEPAGVVE 254 + LT F+ WGWR PF + + ++ L+ R+ L P +AK+ ++ + Sbjct: 182 LLLSWLLTDEQFMSWGWRVPFIFSAVLVIIGLYVRVSLHETPVFAKVAAAKKQVKIPLGT 241 Query: 255 LATTQGRNIIIGALAALASYALFHLVTVFPLSWIKLYSLREATDFLVV---QIWGGLIMA 311 L T R ++G LA+Y LF+++TV+ ++ YS A L + +I L+MA Sbjct: 242 LLTKHVRVTVLGTFIMLATYTLFYIMTVYSMT----YSTAAAPVGLGLPRNEILWMLMMA 297 Query: 312 V---GIV--ISGLIADRFGRRNTLGSMALLIAI--LSAFVPTLMNGGEAGQNTFILIGFA 364 V G++ I+GL+AD FGRR ++ + LI + L AF P L +G A F+L+G + Sbjct: 298 VIGFGVMVPIAGLLADAFGRRKSMVIITTLIILFALFAFTPLLGSGNPALVFVFLLLGLS 357 Query: 365 LLGLSYGQAAGAVTANFKARYRYTGAALTSDLAWLVGAGFAPLVALGLSAHFGMAYVSFY 424 L+GL++G + F RYTGA+ + +++ ++GA AP +A L +H+G+A V Y Sbjct: 358 LMGLTFGPMGALLPELFPTEVRYTGASFSYNVSSILGASVAPYIAAWLQSHYGLAAVGVY 417 Query: 425 LLS 427 L S Sbjct: 418 LAS 420