BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0030.0120.p (174 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_ydeS [K] COG1309 Transcriptional regulator Bsu Bacillus subtilis 122 3e-28 CAC3481 [K] COG1309 Transcriptional regulator Cac Clostridium ac... 121 9e-28 SMa2008 [K] COG1309 Transcriptional regulator Sme Sinorhizobium ... 88 1e-17 mlr3465 [K] COG1309 Transcriptional regulator Mlo Mesorhizobium ... 74 1e-13 Rv1556 [K] COG1309 Transcriptional regulator Mtu Mycobacterium t... 69 7e-12 MT1607 [K] COG1309 Transcriptional regulator MtC Mycobacterium t... 69 7e-12 Rv1167c [K] COG1309 Transcriptional regulator Mtu Mycobacterium ... 67 1e-11 MT1204 [K] COG1309 Transcriptional regulator MtC Mycobacterium t... 67 1e-11 >BS_ydeS [K] COG1309 Transcriptional regulator Bsu Bacillus subtilis Length = 198 Score = 122 bits (307), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 56/156 (35%), Positives = 93/156 (59%) Query: 1 MLEEIGFDKLSLEGVAARAGVGKATIYRWWPNKSALAMEALLRAVEPMPPIGDSGSSRTD 60 +L E GFD ++++ +A RA V KATIY+WW NK+A+ M++ L P+ D+GSS D Sbjct: 24 LLLEKGFDAVTVDKIAERAKVSKATIYKWWSNKAAVIMDSFLSTATDRLPVPDTGSSVQD 83 Query: 61 IELHMLQLSQLLRGKSGRVVREMIALAQFEPESKRIFNDNYLEPRRLALVSVLRRGAQRG 120 I H L++ L + G V++E+I Q + + + + +PRRL +L +G Q+G Sbjct: 84 IVTHATNLARFLTSREGTVIKELIGAGQLDEKLAEEYRTRFFQPRRLQAKGLLEKGIQKG 143 Query: 121 EFREDADLSLVFDLLYAPLLQRLLTGQGDIDERQVQ 156 E RE+ D+ + DL+Y P+ RLL ++++ V+ Sbjct: 144 ELRENLDIEVSIDLIYGPIFYRLLITGDEVNDSYVR 179 >CAC3481 [K] COG1309 Transcriptional regulator Cac Clostridium acetobutylicum Length = 192 Score = 121 bits (303), Expect = 9e-28, Method: Compositional matrix adjust. Identities = 55/151 (36%), Positives = 90/151 (59%) Query: 1 MLEEIGFDKLSLEGVAARAGVGKATIYRWWPNKSALAMEALLRAVEPMPPIGDSGSSRTD 60 +L E GF ++++E +A RA V KATIY+WWPNK+A+ ++ L PI D+GS+ D Sbjct: 24 LLIENGFAEITVEKIAERANVSKATIYKWWPNKAAVIIDGFLNTTNVELPIPDTGSTIQD 83 Query: 61 IELHMLQLSQLLRGKSGRVVREMIALAQFEPESKRIFNDNYLEPRRLALVSVLRRGAQRG 120 + + + ++ L + G V+ E+IA Q++P+ I+ Y PRR +L RG RG Sbjct: 84 MFIQVDNFTKFLTSRKGSVITEIIAEGQYDPKLADIYRKAYFTPRRSISKKILERGILRG 143 Query: 121 EFREDADLSLVFDLLYAPLLQRLLTGQGDID 151 E ++D ++ ++ DL++ P+ RLL ID Sbjct: 144 ELKKDLNIEVIIDLIWGPIFYRLLITGEKID 174 >SMa2008 [K] COG1309 Transcriptional regulator Sme Sinorhizobium meliloti Length = 201 Score = 87.8 bits (216), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 56/152 (36%), Positives = 80/152 (52%), Gaps = 3/152 (1%) Query: 1 MLEEIGFDKLSLEGVAARAGVGKATIYRWWPNKSALAMEALLRAVEPMPPIGDSGSS-RT 59 +L E GF +L++E VAAR+GVGK TIYR W N S LAM AL+ + + G+S R+ Sbjct: 31 ILTEDGFGRLTVEAVAARSGVGKPTIYRHWANASELAMAALMSGDPGI--FAEGGTSLRS 88 Query: 60 DIELHMLQLSQLLRGKSGRVVREMIALAQFEPESKRIFNDNYLEPRRLALVSVLRRGAQR 119 + M L Q GR + +A A E E + F + + R A ++L A R Sbjct: 89 ALAGQMRSLIQAFATTRGRQIAMTLAAADPESEFTKAFRNQVILSSREAGRAMLLEAAAR 148 Query: 120 GEFREDADLSLVFDLLYAPLLQRLLTGQGDID 151 GE DL ++ D++Y P+ RLL G +D Sbjct: 149 GEITLQQDLEVLLDMIYGPVFYRLLVGHRPLD 180 >mlr3465 [K] COG1309 Transcriptional regulator Mlo Mesorhizobium loti Length = 198 Score = 73.9 bits (180), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 56/167 (33%), Positives = 84/167 (50%), Gaps = 4/167 (2%) Query: 1 MLEEIGFDKLSLEGVAARAGVGKATIYRWWPNKSALAMEALLRAVEPMPPIGDSGSSRTD 60 +L E G+ S+E VA RA GK TIYRWWP+K+AL +E R + I D+GS D Sbjct: 31 VLIEAGYAGFSIEAVARRARAGKPTIYRWWPSKAALLLEVYQR--QKRVDIPDTGSLEED 88 Query: 61 IELHMLQLSQLLR-GKSGRVVREMIALAQFEPESKRIFNDNYLEPRRLALVSVLRRGAQR 119 + ++ L R SG V R +IA AQ + E+ Y RR ++ R R Sbjct: 89 LVGFLVNLFAHWRETSSGSVFRSLIAEAQSD-ETAAAALAGYAGARRTHTGQIIERAKAR 147 Query: 120 GEFREDADLSLVFDLLYAPLLQRLLTGQGDIDERQVQAQLKLVLGSI 166 GE D D +V D++ + + LLT + D + ++ ++ +L I Sbjct: 148 GEIAGDIDPGVVADIIASYAWRHLLTNRLDEPKATIRKMVRYLLQGI 194 >Rv1556 [K] COG1309 Transcriptional regulator Mtu Mycobacterium tuberculosis H37Rv Length = 202 Score = 68.6 bits (166), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 46/174 (26%), Positives = 88/174 (50%), Gaps = 11/174 (6%) Query: 1 MLEEIGFDKLSLEGVAARAGVGKATIYRWWPNKSALAMEALLRAVEPMPPIGDSGSSRTD 60 +L+E G+D+L+++ VAA A KAT+YR WP+K+ L + A + + + ++G+ R D Sbjct: 32 LLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVAVPPNTGNLRDD 91 Query: 61 IELHMLQLSQLLR---GKSGRVVREMIALAQFEPESKRIFNDNYLEPRRLALVSVLRRGA 117 +L+L +L+ G+ +R ++ P + +++ R+ + +L++ Sbjct: 92 ----LLRLGELICREVGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRKALIQYILQQAV 147 Query: 118 QRGEFREDADLSLVFDLLYAPLLQRLLTGQGDIDERQVQAQLKLVLGSITLPSL 171 RGE A ++DLL L+ R + + VQA ++ + LPSL Sbjct: 148 DRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQA----LVDDVILPSL 197 >MT1607 [K] COG1309 Transcriptional regulator MtC Mycobacterium tuberculosis CDC1551 Length = 202 Score = 68.6 bits (166), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 46/174 (26%), Positives = 88/174 (50%), Gaps = 11/174 (6%) Query: 1 MLEEIGFDKLSLEGVAARAGVGKATIYRWWPNKSALAMEALLRAVEPMPPIGDSGSSRTD 60 +L+E G+D+L+++ VAA A KAT+YR WP+K+ L + A + + + ++G+ R D Sbjct: 32 LLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVAVPPNTGNLRDD 91 Query: 61 IELHMLQLSQLLR---GKSGRVVREMIALAQFEPESKRIFNDNYLEPRRLALVSVLRRGA 117 +L+L +L+ G+ +R ++ P + +++ R+ + +L++ Sbjct: 92 ----LLRLGELICREVGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRKALIQYILQQAV 147 Query: 118 QRGEFREDADLSLVFDLLYAPLLQRLLTGQGDIDERQVQAQLKLVLGSITLPSL 171 RGE A ++DLL L+ R + + VQA ++ + LPSL Sbjct: 148 DRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQA----LVDDVILPSL 197 >Rv1167c [K] COG1309 Transcriptional regulator Mtu Mycobacterium tuberculosis H37Rv Length = 201 Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 40/121 (33%), Positives = 65/121 (53%) Query: 2 LEEIGFDKLSLEGVAARAGVGKATIYRWWPNKSALAMEALLRAVEPMPPIGDSGSSRTDI 61 LE G+ L++EG+AARA GKA +YR W K L + A+ A+ P+P S+R ++ Sbjct: 31 LESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQYALPPVPEPRADRSARENL 90 Query: 62 ELHMLQLSQLLRGKSGRVVREMIALAQFEPESKRIFNDNYLEPRRLALVSVLRRGAQRGE 121 ++L GK+ E+++ EPE + IF ++ PR + S+L+ G + GE Sbjct: 91 LAVFTANCEILAGKTALPSMEIVSQLLHEPELRAIFINSVWAPRLRIVESILQAGVRSGE 150 Query: 122 F 122 Sbjct: 151 I 151 >MT1204 [K] COG1309 Transcriptional regulator MtC Mycobacterium tuberculosis CDC1551 Length = 201 Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 40/121 (33%), Positives = 65/121 (53%) Query: 2 LEEIGFDKLSLEGVAARAGVGKATIYRWWPNKSALAMEALLRAVEPMPPIGDSGSSRTDI 61 LE G+ L++EG+AARA GKA +YR W K L + A+ A+ P+P S+R ++ Sbjct: 31 LESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQYALPPVPEPRADRSARENL 90 Query: 62 ELHMLQLSQLLRGKSGRVVREMIALAQFEPESKRIFNDNYLEPRRLALVSVLRRGAQRGE 121 ++L GK+ E+++ EPE + IF ++ PR + S+L+ G + GE Sbjct: 91 LAVFTANCEILAGKTALPSMEIVSQLLHEPELRAIFINSVWAPRLRIVESILQAGVRSGE 150 Query: 122 F 122 Sbjct: 151 I 151