BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0030.0084.p (330 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value alr0058 [CHR] COG1052 Lactate dehydrogenase and related dehydrog... 376 e-104 AGl1952 [CHR] COG1052 Lactate dehydrogenase and related dehydrog... 364 e-100 PA0927 [CHR] COG1052 Lactate dehydrogenase and related dehydroge... 357 2e-98 RSc3131 [CHR] COG1052 Lactate dehydrogenase and related dehydrog... 338 9e-93 slr1556 [CHR] COG1052 Lactate dehydrogenase and related dehydrog... 336 5e-92 NMA1944 [CHR] COG1052 Lactate dehydrogenase and related dehydrog... 325 8e-89 NMB1685 [CHR] COG1052 Lactate dehydrogenase and related dehydrog... 323 2e-88 HI0085 [CHR] COG1052 Lactate dehydrogenase and related dehydroge... 322 7e-88 VCA0192 [CHR] COG1052 Lactate dehydrogenase and related dehydrog... 315 1e-85 ldhA [CHR] COG1052 Lactate dehydrogenase and related dehydrogena... 314 1e-85 >alr0058 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases Nos Nostoc sp. PCC 7120 Length = 341 Score = 376 bits (966), Expect = e-104, Method: Compositional matrix adjust. Identities = 177/321 (55%), Positives = 231/321 (71%) Query: 1 MKTAVFSARRYDQTLLARANAAHGHELVFLQDRLEAGTAQLAAGCQAVAAFVNDDLGGVV 60 MK AVFS + YD+ L ANA HEL F + RL TA LAAG AV FV+D + Sbjct: 1 MKVAVFSTKAYDRQFLEAANAPKHHELAFFEPRLNQDTAILAAGFPAVCVFVHDQVDAAT 60 Query: 61 LEKLAELGVRFVTTRSTGFNHIDVAAARALGLTVARVADYSPYSVAEFAVGLLQAVNRKI 120 LE LA G R + R GFN++D+ AA LG+TV RV YSPY VAE AVGL+ ++NRKI Sbjct: 61 LEILASRGTRLIVLRCAGFNNVDLKAANKLGVTVVRVPAYSPYGVAEHAVGLILSLNRKI 120 Query: 121 ARASMRTREGNFELDGLMGVDLHGKTVGVIGTGKIGVLFARIMAGFGCQILGSDVHRNPD 180 RA R REGNF LDGL+G +++G+TVG+IGTGKIG++ +IM GFGC++L DV+RNP+ Sbjct: 121 HRAYNRVREGNFALDGLLGFNINGRTVGIIGTGKIGLILGQIMKGFGCRLLAYDVYRNPE 180 Query: 181 FDALGGRYVERTELFAASDVISLHCPLTEATRYLVNAQSLALAKPGCILVNTSRGGLVDT 240 ++LGG YVE ELFA SD+ISLHCPL T +L+NA+++ KPG +L+NTSRG L+ T Sbjct: 181 MESLGGEYVELPELFANSDIISLHCPLMPQTHHLINAEAIEQVKPGVMLINTSRGALIHT 240 Query: 241 EAAIAALKSGRLRGLAIDVYEQEASLFFQDLSSTIITDDVIQRLVSFPNVIVTGHQAFFT 300 +A I LK+G++ L +DVYEQE+ LFF+DLS II DD+ QRL +FPNV++TGHQAFFT Sbjct: 241 QAVIEGLKTGKIGSLGVDVYEQESELFFEDLSGEIIQDDIFQRLTTFPNVLITGHQAFFT 300 Query: 301 EEAIGQIMQTTIENLSAFAAG 321 E+A+ I +TT+ N++ G Sbjct: 301 EDALRNIAETTLNNIADIEQG 321 >AGl1952 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 337 Score = 364 bits (935), Expect = e-100, Method: Compositional matrix adjust. Identities = 178/318 (55%), Positives = 229/318 (72%), Gaps = 1/318 (0%) Query: 1 MKTAVFSARRYDQTLLARANAAHGHELVFLQDRLEAGTAQLAAGCQAVAAFVNDDLGGVV 60 M+ V+SA+ YD+ L A A G +L + + RL T LA G A+ AFVNDDL V Sbjct: 1 MRIVVYSAKPYDRQFLDEA-ARPGTDLQYCEARLSPETVALADGAVAICAFVNDDLSRPV 59 Query: 61 LEKLAELGVRFVTTRSTGFNHIDVAAARALGLTVARVADYSPYSVAEFAVGLLQAVNRKI 120 LEKLA +GVR V R GFN +D+AAA LGLT+ARV YSPY+VAE + L+ ++NRKI Sbjct: 60 LEKLAGMGVRLVALRCAGFNQVDLAAAEKLGLTIARVPAYSPYAVAEHTMALILSLNRKI 119 Query: 121 ARASMRTREGNFELDGLMGVDLHGKTVGVIGTGKIGVLFARIMAGFGCQILGSDVHRNPD 180 RA R REGNF LDGL+G DLHGKT+G++GTGKIG +FARI AGFGC+++G D+H NPD Sbjct: 120 HRAYNRVREGNFALDGLLGFDLHGKTMGIVGTGKIGAIFARIAAGFGCRLIGHDLHPNPD 179 Query: 181 FDALGGRYVERTELFAASDVISLHCPLTEATRYLVNAQSLALAKPGCILVNTSRGGLVDT 240 +ALG Y R ELF SD+++L CPLT TR+L+ ++L L K G +L+NTSRG ++DT Sbjct: 180 CEALGMTYGTREELFRTSDIVALMCPLTRETRHLIRRETLPLLKKGVMLINTSRGAIIDT 239 Query: 241 EAAIAALKSGRLRGLAIDVYEQEASLFFQDLSSTIITDDVIQRLVSFPNVIVTGHQAFFT 300 AAI LK G + L IDVYE+EA LFF+DLS+ ++ DDV RL++FPNV+VTGHQ FFT Sbjct: 240 PAAITGLKDGTIGSLGIDVYEEEADLFFEDLSNDVLRDDVFARLLTFPNVLVTGHQGFFT 299 Query: 301 EEAIGQIMQTTIENLSAF 318 +EA+ I TTI N+ +F Sbjct: 300 QEALKNIADTTIGNIESF 317 >PA0927 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases Pae Pseudomonas aeruginosa Length = 329 Score = 357 bits (917), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 180/321 (56%), Positives = 225/321 (70%) Query: 1 MKTAVFSARRYDQTLLARANAAHGHELVFLQDRLEAGTAQLAAGCQAVAAFVNDDLGGVV 60 M+ FS++ YD +N HG EL F Q L+A TA LA G + V AFVNDDL V Sbjct: 1 MRILFFSSQAYDSESFQASNHRHGFELHFQQAHLQADTAVLAQGFEVVCAFVNDDLSRPV 60 Query: 61 LEKLAELGVRFVTTRSTGFNHIDVAAARALGLTVARVADYSPYSVAEFAVGLLQAVNRKI 120 LE+LA G R V RS G+NH+D+AAA ALGL V V YSP++VAE AVGL+ +NR++ Sbjct: 61 LERLAAGGTRLVALRSAGYNHVDLAAAEALGLPVVHVPAYSPHAVAEHAVGLILTLNRRL 120 Query: 121 ARASMRTREGNFELDGLMGVDLHGKTVGVIGTGKIGVLFARIMAGFGCQILGSDVHRNPD 180 RA RTREG+F L GL G DLHGK VGVIGTG+IG FARIMAGFGC++L D + NP Sbjct: 121 HRAYNRTREGDFSLHGLTGFDLHGKRVGVIGTGQIGETFARIMAGFGCELLAYDPYPNPR 180 Query: 181 FDALGGRYVERTELFAASDVISLHCPLTEATRYLVNAQSLALAKPGCILVNTSRGGLVDT 240 ALGGRY+ L A SD++SLHCPLT TR+L++AQ LA KPG +L+NT RG LV+ Sbjct: 181 IQALGGRYLALDALLAESDIVSLHCPLTADTRHLIDAQRLATMKPGAMLINTGRGALVNA 240 Query: 241 EAAIAALKSGRLRGLAIDVYEQEASLFFQDLSSTIITDDVIQRLVSFPNVIVTGHQAFFT 300 A I ALKSG+L L +DVYE+EA +FF+D S + DDV+ RL+SFPNV+VT HQAF T Sbjct: 241 AALIEALKSGQLGYLGLDVYEEEADIFFEDRSDQPLQDDVLARLLSFPNVVVTAHQAFLT 300 Query: 301 EEAIGQIMQTTIENLSAFAAG 321 EA+ I TT++N++A+ G Sbjct: 301 REALAAIADTTLDNIAAWQDG 321 >RSc3131 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases Rso Ralstonia solanacearum Length = 342 Score = 338 bits (867), Expect = 9e-93, Method: Compositional matrix adjust. Identities = 175/314 (55%), Positives = 221/314 (70%), Gaps = 2/314 (0%) Query: 1 MKTAVFSARRYDQTLL--ARANAAHGHELVFLQDRLEAGTAQLAAGCQAVAAFVNDDLGG 58 M+ FS+ RYD+ A+A HG ELVF + L+ TA LAAG + V FVND L Sbjct: 12 MRILFFSSHRYDEDAFRAAQARGGHGFELVFQRAHLDVHTAPLAAGFEVVCPFVNDCLDA 71 Query: 59 VVLEKLAELGVRFVTTRSTGFNHIDVAAARALGLTVARVADYSPYSVAEFAVGLLQAVNR 118 VL LA G R + RS GFNH+D+AAA+ LGLTV RV YSP++VAE AVG++ +NR Sbjct: 72 GVLAVLAAGGARLIALRSAGFNHVDLAAAQRLGLTVVRVPAYSPHAVAEHAVGMILTLNR 131 Query: 119 KIARASMRTREGNFELDGLMGVDLHGKTVGVIGTGKIGVLFARIMAGFGCQILGSDVHRN 178 ++ RA RTREG+F LDGL+G DL GKTVGV+GTG+IG +FARIMAGFGC++L D Sbjct: 132 RLHRACNRTREGDFSLDGLLGFDLAGKTVGVVGTGQIGQVFARIMAGFGCRLLAFDPFPQ 191 Query: 179 PDFDALGGRYVERTELFAASDVISLHCPLTEATRYLVNAQSLALAKPGCILVNTSRGGLV 238 P ALG YV L A SD++SLHCPL T +L++A +LA K G +L+NTSRGGLV Sbjct: 192 PALAALGVTYVPLPALLAQSDIVSLHCPLNADTHHLIDAGALASMKTGAMLINTSRGGLV 251 Query: 239 DTEAAIAALKSGRLRGLAIDVYEQEASLFFQDLSSTIITDDVIQRLVSFPNVIVTGHQAF 298 D+ A I ALKSG+L L +DVYE+EA LFF+D S+ ++ DDV+ RL++FPNVIVT HQAF Sbjct: 252 DSPALIDALKSGQLGHLGLDVYEEEADLFFEDRSADVLQDDVLARLLTFPNVIVTAHQAF 311 Query: 299 FTEEAIGQIMQTTI 312 FT EA+ I TT+ Sbjct: 312 FTREALAGIADTTL 325 >slr1556 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases Syn Synechocystis Length = 333 Score = 336 bits (861), Expect = 5e-92, Method: Compositional matrix adjust. Identities = 166/331 (50%), Positives = 212/331 (64%), Gaps = 1/331 (0%) Query: 1 MKTAVFSARRYDQTLLARANAAHGHELVFLQDRLEAGTAQLAAGCQAVAAFVNDDLGGVV 60 MK A FS++ YD+ +AN H E+VF +L TA LA C + FVND V Sbjct: 1 MKIAFFSSKAYDRQFFQQANHPHQREMVFFDAQLNLDTAILAEDCPVICLFVNDQAPAPV 60 Query: 61 LEKLAELGVRFVTTRSTGFNHIDVAAARALGLTVARVADYSPYSVAEFAVGLLQAVNRKI 120 LEKLA G + + RS G+N++D+ A LGL V V YSP++VAE VGL+ A+NRK+ Sbjct: 61 LEKLAAQGTKLIALRSAGYNNVDLKTAADLGLKVVHVPSYSPHAVAEHTVGLILALNRKL 120 Query: 121 ARASMRTREGNFELDGLMGVDLHGKTVGVIGTGKIGVLFARIMAGFGCQILGSDVHRNPD 180 RA R R+ NF L+GL+G DLHG TVGVIGTGKIG+ FA+IM GFGC +LG D N Sbjct: 121 YRAYNRVRDDNFSLEGLLGFDLHGTTVGVIGTGKIGLAFAQIMNGFGCHLLGYDAFPNDK 180 Query: 181 FDALG-GRYVERTELFAASDVISLHCPLTEATRYLVNAQSLALAKPGCILVNTSRGGLVD 239 F A+G YV EL A SD+ISLHCPL T YL+N ++A KPG +L+NTSRG L+D Sbjct: 181 FTAIGQALYVSLNELLAHSDIISLHCPLLPETHYLINTNTIAQMKPGVMLINTSRGHLID 240 Query: 240 TEAAIAALKSGRLRGLAIDVYEQEASLFFQDLSSTIITDDVIQRLVSFPNVIVTGHQAFF 299 T+A I +KS ++ L IDVYE+E LFF D S TII DD Q L SFPNV++T HQ FF Sbjct: 241 TQAVIQGIKSHKIGFLGIDVYEEEEELFFTDHSDTIIQDDTFQLLQSFPNVMITAHQGFF 300 Query: 300 TEEAIGQIMQTTIENLSAFAAGDNLGERLVA 330 T A+ I TT+ N++ F L +++ Sbjct: 301 THNALQTIAATTLANIAEFEQNKPLTYQVIC 331 >NMA1944 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases NmA Neisseria meningitidis Z2491 Length = 332 Score = 325 bits (833), Expect = 8e-89, Method: Compositional matrix adjust. Identities = 160/315 (50%), Positives = 213/315 (67%) Query: 1 MKTAVFSARRYDQTLLARANAAHGHELVFLQDRLEAGTAQLAAGCQAVAAFVNDDLGGVV 60 MK A++ + YD+ RAN G EL F L+A TA++A G +AV FVNDD V Sbjct: 1 MKIAIYGTKSYDREHFTRANRHFGFELEFFDFMLDAKTAKMAEGAEAVCIFVNDDGSRPV 60 Query: 61 LEKLAELGVRFVTTRSTGFNHIDVAAARALGLTVARVADYSPYSVAEFAVGLLQAVNRKI 120 LEKLA++GV+ V R GFN++D+ AA LGL V RV YSP SVAE VGL+ +NR+I Sbjct: 61 LEKLAQIGVKTVALRCAGFNNVDLKAAEELGLKVVRVPAYSPESVAEHTVGLMLTLNRRI 120 Query: 121 ARASMRTREGNFELDGLMGVDLHGKTVGVIGTGKIGVLFARIMAGFGCQILGSDVHRNPD 180 +A RTR+ NF L+GL G +++GKT GVIGTGKIG+ RI+ GFG +L D NP+ Sbjct: 121 HKAYQRTRDANFSLEGLTGFNMYGKTAGVIGTGKIGIATMRILKGFGMNLLAHDPFCNPE 180 Query: 181 FDALGGRYVERTELFAASDVISLHCPLTEATRYLVNAQSLALAKPGCILVNTSRGGLVDT 240 + +GGRYV+ EL+A SD+I+LHCP T Y++N + K G +++NTSRGGL+D+ Sbjct: 181 AEKIGGRYVDLDELYAQSDIITLHCPSTPENHYMLNEAAFDKMKDGVMIINTSRGGLIDS 240 Query: 241 EAAIAALKSGRLRGLAIDVYEQEASLFFQDLSSTIITDDVIQRLVSFPNVIVTGHQAFFT 300 AAI ALK ++ L +DVYE E LFF+D S+ +ITDDV +RL S NV+ TGHQAF T Sbjct: 241 AAAIEALKRRKIGALGMDVYENERELFFEDKSNDVITDDVFRRLSSCHNVLFTGHQAFLT 300 Query: 301 EEAIGQIMQTTIENL 315 EEA+G I + T+ N+ Sbjct: 301 EEALGNISEVTLSNI 315 >NMB1685 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases Nme Neisseria meningitidis MC58 Length = 332 Score = 323 bits (829), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 159/315 (50%), Positives = 213/315 (67%) Query: 1 MKTAVFSARRYDQTLLARANAAHGHELVFLQDRLEAGTAQLAAGCQAVAAFVNDDLGGVV 60 MK A++ + YD+ RAN G EL F L+A TA++A G +AV FVNDD V Sbjct: 1 MKIAIYGTKSYDREHFTRANRHFGFELEFFDFMLDAKTAKMAEGAEAVCIFVNDDGSRPV 60 Query: 61 LEKLAELGVRFVTTRSTGFNHIDVAAARALGLTVARVADYSPYSVAEFAVGLLQAVNRKI 120 LEKLA++GV+ V R GFN++D+ AA LGL V RV YSP SVAE VGL+ +NR+I Sbjct: 61 LEKLAQIGVKTVALRCAGFNNVDLKAAEELGLKVVRVPAYSPESVAEHTVGLMLTLNRRI 120 Query: 121 ARASMRTREGNFELDGLMGVDLHGKTVGVIGTGKIGVLFARIMAGFGCQILGSDVHRNPD 180 +A RTR+ NF L+GL G +++GKT GVIGTGKIG+ RI+ GFG +L D NP+ Sbjct: 121 HKAYQRTRDANFSLEGLTGFNMYGKTAGVIGTGKIGIATMRILKGFGMNLLAYDPFCNPE 180 Query: 181 FDALGGRYVERTELFAASDVISLHCPLTEATRYLVNAQSLALAKPGCILVNTSRGGLVDT 240 + +GG+YV+ EL+A SD+I+LHCP T Y++N + K G +++NTSRGGL+D+ Sbjct: 181 AEKIGGKYVDLDELYARSDIITLHCPATPENHYMLNEAAFDKMKDGVMIINTSRGGLIDS 240 Query: 241 EAAIAALKSGRLRGLAIDVYEQEASLFFQDLSSTIITDDVIQRLVSFPNVIVTGHQAFFT 300 AAI ALK ++ L +DVYE E LFF+D S+ +ITDDV +RL S NV+ TGHQAF T Sbjct: 241 AAAIEALKRRKIGALGMDVYENERELFFEDKSNDVITDDVFRRLSSCHNVLFTGHQAFLT 300 Query: 301 EEAIGQIMQTTIENL 315 EEA+G I + T+ N+ Sbjct: 301 EEALGNISEVTLSNI 315 >HI0085 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases Hin Haemophilus influenzae Length = 331 Score = 322 bits (825), Expect = 7e-88, Method: Compositional matrix adjust. Identities = 157/321 (48%), Positives = 213/321 (66%) Query: 1 MKTAVFSARRYDQTLLARANAAHGHELVFLQDRLEAGTAQLAAGCQAVAAFVNDDLGGVV 60 MK A++S + YD+ + NA + +L F L T +LA C+ V FVND+ V Sbjct: 1 MKIAIYSTKSYDRKYIELINAKYNFDLEFFDFMLNESTVRLAEHCEVVCIFVNDNGSRKV 60 Query: 61 LEKLAELGVRFVTTRSTGFNHIDVAAARALGLTVARVADYSPYSVAEFAVGLLQAVNRKI 120 LEKLA LGV+ V R GFN++D+ AA+ LG+ V RV YSP +VAE +GL+ +NR+I Sbjct: 61 LEKLAALGVKIVALRCAGFNNVDLKAAQELGIQVVRVPAYSPEAVAEHTIGLMMTLNRRI 120 Query: 121 ARASMRTREGNFELDGLMGVDLHGKTVGVIGTGKIGVLFARIMAGFGCQILGSDVHRNPD 180 RA RTRE NF L+GL+G +++G+TVGVIGTGKIG+ RI+ GFG IL D +NP Sbjct: 121 HRAYQRTREANFSLEGLIGFNMYGRTVGVIGTGKIGIAVMRILKGFGMNILAYDPFKNPV 180 Query: 181 FDALGGRYVERTELFAASDVISLHCPLTEATRYLVNAQSLALAKPGCILVNTSRGGLVDT 240 + LGG+YVE EL+A S VI+LHCP T +L+N ++ A K G ++VNTSRG L+DT Sbjct: 181 VEELGGQYVELDELYAKSHVITLHCPATPENYHLLNCEAFAKMKDGVMIVNTSRGSLIDT 240 Query: 241 EAAIAALKSGRLRGLAIDVYEQEASLFFQDLSSTIITDDVIQRLVSFPNVIVTGHQAFFT 300 +AAI ALK ++ L +DVYE E LFF+D S+ +I DD+ +RL S NV++TGHQAF T Sbjct: 241 QAAIDALKQRKIGALGMDVYENERDLFFEDKSNEVIQDDIFRRLSSCHNVLLTGHQAFLT 300 Query: 301 EEAIGQIMQTTIENLSAFAAG 321 EEA+ I T+ N+ +G Sbjct: 301 EEALTNIADVTLSNIYKLKSG 321 >VCA0192 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases Vch Vibrio cholerae Length = 331 Score = 315 bits (806), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 159/324 (49%), Positives = 211/324 (65%) Query: 6 FSARRYDQTLLARANAAHGHELVFLQDRLEAGTAQLAAGCQAVAAFVNDDLGGVVLEKLA 65 FSA+ YD ++ L F RL TAQ+A GC+ V AFVND+L VLE+L Sbjct: 7 FSAKHYDIASFSKLVDPTQLSLHFHDFRLTDKTAQMAKGCEVVCAFVNDELHASVLEQLY 66 Query: 66 ELGVRFVTTRSTGFNHIDVAAARALGLTVARVADYSPYSVAEFAVGLLQAVNRKIARASM 125 + G R + R GF+ +D+ AA+ LG+ V RV YSP +VAE VG++ +NR+ +A Sbjct: 67 QGGTRLIAMRCAGFDKVDLEAAKRLGMQVVRVPAYSPEAVAEHTVGMMLCLNRRFHKAYQ 126 Query: 126 RTREGNFELDGLMGVDLHGKTVGVIGTGKIGVLFARIMAGFGCQILGSDVHRNPDFDALG 185 RTR+ NF LDGL+G + HGKTVGVIG+GKIGV RI+ G G QIL D + NPD ALG Sbjct: 127 RTRDANFSLDGLVGFNFHGKTVGVIGSGKIGVATMRILQGLGMQILCFDPYPNPDAIALG 186 Query: 186 GRYVERTELFAASDVISLHCPLTEATRYLVNAQSLALAKPGCILVNTSRGGLVDTEAAIA 245 RYVE +ELFA SDVI+LHCP+++ +L+N + K G +++NTSRG L+D+ AAI Sbjct: 187 ARYVELSELFAQSDVITLHCPMSKENYHLLNESAFDQMKDGVMIINTSRGELLDSVAAIE 246 Query: 246 ALKSGRLRGLAIDVYEQEASLFFQDLSSTIITDDVIQRLVSFPNVIVTGHQAFFTEEAIG 305 ALK GR+ L +DVY+ E LFFQD S+ +I DDV +RL + NV+ TGHQAF TE+A+ Sbjct: 247 ALKRGRIGALGLDVYDNEKDLFFQDKSNDVIVDDVFRRLSACHNVLFTGHQAFLTEDALN 306 Query: 306 QIMQTTIENLSAFAAGDNLGERLV 329 I QTT+ N+ F G L+ Sbjct: 307 NIAQTTLNNIQLFFDNQASGNELI 330 >ldhA [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases Eco Escherichia coli K12 Length = 329 Score = 314 bits (805), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 159/329 (48%), Positives = 215/329 (65%) Query: 1 MKTAVFSARRYDQTLLARANAAHGHELVFLQDRLEAGTAQLAAGCQAVAAFVNDDLGGVV 60 MK AV+S ++YD+ L + N + G EL F L TA+ A GC+AV FVNDD V Sbjct: 1 MKLAVYSTKQYDKKYLQQVNESFGFELEFFDFLLTEKTAKTANGCEAVCIFVNDDGSRPV 60 Query: 61 LEKLAELGVRFVTTRSTGFNHIDVAAARALGLTVARVADYSPYSVAEFAVGLLQAVNRKI 120 LE+L + GV+++ R GFN++D+ AA+ LGL V RV Y P +VAE A+G++ +NR+I Sbjct: 61 LEELKKHGVKYIALRCAGFNNVDLDAAKELGLKVVRVPAYDPEAVAEHAIGMMMTLNRRI 120 Query: 121 ARASMRTREGNFELDGLMGVDLHGKTVGVIGTGKIGVLFARIMAGFGCQILGSDVHRNPD 180 RA RTR+ NF L+GL G ++GKT GVIGTGKIGV RI+ GFG ++L D + + Sbjct: 121 HRAYQRTRDANFSLEGLTGFTMYGKTAGVIGTGKIGVAMLRILKGFGMRLLAFDPYPSAA 180 Query: 181 FDALGGRYVERTELFAASDVISLHCPLTEATRYLVNAQSLALAKPGCILVNTSRGGLVDT 240 LG YV+ LF+ SDVISLHCPLT +L+N + K G ++VNTSRG L+D+ Sbjct: 181 ALELGVEYVDLPTLFSESDVISLHCPLTPENYHLLNEAAFEQMKNGVMIVNTSRGALIDS 240 Query: 241 EAAIAALKSGRLRGLAIDVYEQEASLFFQDLSSTIITDDVIQRLVSFPNVIVTGHQAFFT 300 +AAI ALK+ ++ L +DVYE E LFF+D S+ +I DDV +RL + NV+ TGHQAF T Sbjct: 241 QAAIEALKNQKIGSLGMDVYENERDLFFEDKSNDVIQDDVFRRLSACHNVLFTGHQAFLT 300 Query: 301 EEAIGQIMQTTIENLSAFAAGDNLGERLV 329 EA+ I QTT++NLS G+ LV Sbjct: 301 AEALTSISQTTLQNLSNLEKGETCPNELV 329