BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0030.0053.p (255 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value NMB0380 [T] COG0664 cAMP-binding proteins - catabolite gene acti... 235 6e-62 NMA2107 [T] COG0664 cAMP-binding proteins - catabolite gene acti... 235 6e-62 RSc1283 [T] COG0664 cAMP-binding proteins - catabolite gene acti... 225 7e-59 RSc0190 [T] COG0664 cAMP-binding proteins - catabolite gene acti... 221 1e-57 STM1660 [T] COG0664 cAMP-binding proteins - catabolite gene acti... 211 1e-54 fnr [T] COG0664 cAMP-binding proteins - catabolite gene activato... 208 7e-54 Zfnr [T] COG0664 cAMP-binding proteins - catabolite gene activat... 208 7e-54 ECs1915 [T] COG0664 cAMP-binding proteins - catabolite gene acti... 208 7e-54 PA1544 [T] COG0664 cAMP-binding proteins - catabolite gene activ... 201 9e-52 HI1425 [T] COG0664 cAMP-binding proteins - catabolite gene activ... 200 3e-51 >NMB0380 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Nme Neisseria meningitidis MC58 Length = 244 Score = 235 bits (600), Expect = 6e-62, Method: Compositional matrix adjust. Identities = 113/232 (48%), Positives = 168/232 (72%) Query: 19 HALRASCSACSMHQLCLPMGLDQGDMQRLEQVINRRRKVKRDETLYRLNDKFDMLYAIRL 78 H ++ CS+CS+ +LCLP+GL ++ +L+ VI + R++K+ E L+ + + F L+AIR Sbjct: 8 HQMKTLCSSCSLRELCLPVGLLPNELSQLDAVIRQSRRLKKGEYLFCVGEAFTSLFAIRS 67 Query: 79 GHFKTFQHNPNGGQQITGFQMAGELLGMDAIGAGHHLCEAVALEDSEVCEIPFASLEDLF 138 G FKT + +G Q+TGF M+GEL+GMD I + H C+AVALEDSEVCE+PF +E+L Sbjct: 68 GFFKTTVASQDGRDQVTGFFMSGELIGMDGICSHVHSCDAVALEDSEVCELPFTHIEELG 127 Query: 139 RDMPTLLRQFHRMMSLEISREQRVMLTLGSMTAQQKMAAFLLNLSSRYMSRGYSSTRFQL 198 +++P+L F RMMS EI R+Q VML LG+M A++++AAFLLNLS R SRG+++ F L Sbjct: 128 QNIPSLRTHFFRMMSREIVRDQGVMLLLGNMRAEERIAAFLLNLSQRLYSRGFAANDFIL 187 Query: 199 RMTREEIGNYLGLAVESVSRLLTNFKKSGVIEVNHRDVELCDLPTLRAVALG 250 RM+REEIG+YLGL +E+VSR L+ F + G+I V H+ +++ +L L+ + G Sbjct: 188 RMSREEIGSYLGLKLETVSRTLSKFHQEGLISVEHKHIKILNLQVLKKMVSG 239 >NMA2107 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases NmA Neisseria meningitidis Z2491 Length = 244 Score = 235 bits (600), Expect = 6e-62, Method: Compositional matrix adjust. Identities = 113/232 (48%), Positives = 168/232 (72%) Query: 19 HALRASCSACSMHQLCLPMGLDQGDMQRLEQVINRRRKVKRDETLYRLNDKFDMLYAIRL 78 H ++ CS+CS+ +LCLP+GL ++ +L+ VI + R++K+ E L+ + + F L+AIR Sbjct: 8 HQMKTLCSSCSLRELCLPVGLLPNELSQLDAVIRQSRRLKKGEYLFCVGEAFTSLFAIRS 67 Query: 79 GHFKTFQHNPNGGQQITGFQMAGELLGMDAIGAGHHLCEAVALEDSEVCEIPFASLEDLF 138 G FKT + +G Q+TGF M+GEL+GMD I + H C+AVALEDSEVCE+PF +E+L Sbjct: 68 GFFKTTVASQDGRDQVTGFFMSGELIGMDGICSHVHSCDAVALEDSEVCELPFTHIEELG 127 Query: 139 RDMPTLLRQFHRMMSLEISREQRVMLTLGSMTAQQKMAAFLLNLSSRYMSRGYSSTRFQL 198 +++P+L F RMMS EI R+Q VML LG+M A++++AAFLLNLS R SRG+++ F L Sbjct: 128 QNIPSLRTHFFRMMSREIVRDQGVMLLLGNMRAEERIAAFLLNLSQRLYSRGFAANDFIL 187 Query: 199 RMTREEIGNYLGLAVESVSRLLTNFKKSGVIEVNHRDVELCDLPTLRAVALG 250 RM+REEIG+YLGL +E+VSR L+ F + G+I V H+ +++ +L L+ + G Sbjct: 188 RMSREEIGSYLGLKLETVSRTLSKFHQEGLISVEHKHIKILNLQVLKKMVSG 239 >RSc1283 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Rso Ralstonia solanacearum Length = 242 Score = 225 bits (574), Expect = 7e-59, Method: Compositional matrix adjust. Identities = 105/227 (46%), Positives = 160/227 (70%) Query: 25 CSACSMHQLCLPMGLDQGDMQRLEQVINRRRKVKRDETLYRLNDKFDMLYAIRLGHFKTF 84 CS C + Q+CLP+G++ D+++++ ++ R ++K+ + LY L + + +Y IR G KT Sbjct: 14 CSTCVLGQICLPVGMNADDVRKMDDLVTERIRIKKGQVLYALGEPLEAVYGIRFGTLKTH 73 Query: 85 QHNPNGGQQITGFQMAGELLGMDAIGAGHHLCEAVALEDSEVCEIPFASLEDLFRDMPTL 144 +G QITGF + GE++G+D IG H+ +A ALED+EVC + +A L+ L R +P+L Sbjct: 74 LTLEDGRHQITGFHLPGEIVGLDGIGEMRHVSDATALEDTEVCVVRYAELQQLSRRLPSL 133 Query: 145 LRQFHRMMSLEISREQRVMLTLGSMTAQQKMAAFLLNLSSRYMSRGYSSTRFQLRMTREE 204 QF R+MS EIS++ ++LTLGSM A++++AAFLLNLS R RGYSST F LRM+REE Sbjct: 134 QHQFLRIMSKEISQDHLMLLTLGSMRAEERLAAFLLNLSRRSAERGYSSTEFVLRMSREE 193 Query: 205 IGNYLGLAVESVSRLLTNFKKSGVIEVNHRDVELCDLPTLRAVALGN 251 +G+YLGL +E+VSRL + F ++G+I++ R V+L D+ LR V G+ Sbjct: 194 LGSYLGLKLETVSRLFSRFAEAGLIQIRQRHVKLIDMAGLRQVMTGH 240 >RSc0190 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Rso Ralstonia solanacearum Length = 266 Score = 221 bits (563), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 105/225 (46%), Positives = 150/225 (66%) Query: 20 ALRASCSACSMHQLCLPMGLDQGDMQRLEQVINRRRKVKRDETLYRLNDKFDMLYAIRLG 79 AL + C+ C MH +C+ + +R++++++ RKV + E L+R D F LYAIR G Sbjct: 39 ALSSQCANCMMHWVCIAGAVPSTQQERVDRMVHTWRKVGKGEALFRAGDTFHALYAIRSG 98 Query: 80 HFKTFQHNPNGGQQITGFQMAGELLGMDAIGAGHHLCEAVALEDSEVCEIPFASLEDLFR 139 FKT +PNG +TGFQ+AGE LG+D I A H C+A+ALEDS VC +PF +EDL + Sbjct: 99 SFKTVVSHPNGSSHVTGFQLAGETLGLDGIAADRHTCDAIALEDSTVCSMPFHCVEDLCQ 158 Query: 140 DMPTLLRQFHRMMSLEISREQRVMLTLGSMTAQQKMAAFLLNLSSRYMSRGYSSTRFQLR 199 + L + H++++ EI RE +ML L +TA+ ++A FLLNLSSR RGYS + F LR Sbjct: 159 AIRPLQHRLHQLLAEEIVRESGLMLLLARLTAEARVATFLLNLSSRMQDRGYSGSCFTLR 218 Query: 200 MTREEIGNYLGLAVESVSRLLTNFKKSGVIEVNHRDVELCDLPTL 244 MTREEIG+YLG+ +E+VSR L+ F++ G I VN + +EL + L Sbjct: 219 MTREEIGSYLGMQLETVSRALSRFQREGWISVNGKQIELANKAAL 263 >STM1660 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Sty Salmonella typhimurium LT2 Length = 264 Score = 211 bits (537), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 101/224 (45%), Positives = 152/224 (67%) Query: 25 CSACSMHQLCLPMGLDQGDMQRLEQVINRRRKVKRDETLYRLNDKFDMLYAIRLGHFKTF 84 C CS+ QLC+P L++ ++ +L+ +I R++ +++ +TL++ D+ LYAIR G K++ Sbjct: 34 CQDCSISQLCIPFTLNEHELDQLDNIIERKKPIQKGQTLFKAGDELKSLYAIRSGTIKSY 93 Query: 85 QHNPNGGQQITGFQMAGELLGMDAIGAGHHLCEAVALEDSEVCEIPFASLEDLFRDMPTL 144 G +QITGF +AG+L+G DAIG+GHH A ALE S VCEIPF +L+DL MP L Sbjct: 94 TITEQGDEQITGFHLAGDLVGFDAIGSGHHPSFAQALETSMVCEIPFETLDDLSGKMPNL 153 Query: 145 LRQFHRMMSLEISREQRVMLTLGSMTAQQKMAAFLLNLSSRYMSRGYSSTRFQLRMTREE 204 +Q R+MS EI +Q ++L L A++++AAF+ NLS R+ RG+S F+L MTR + Sbjct: 154 RQQMMRLMSGEIKGDQDMILLLSKKNAEERLAAFIYNLSRRFAQRGFSPREFRLTMTRGD 213 Query: 205 IGNYLGLAVESVSRLLTNFKKSGVIEVNHRDVELCDLPTLRAVA 248 IGNYLGL VE++SRLL F+KSG++ V + + + + L A+A Sbjct: 214 IGNYLGLTVETISRLLGRFQKSGMLAVKGKYITIENSDALAALA 257 >fnr [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Eco Escherichia coli K12 Length = 250 Score = 208 bits (530), Expect = 7e-54, Method: Compositional matrix adjust. Identities = 98/214 (45%), Positives = 147/214 (68%) Query: 25 CSACSMHQLCLPMGLDQGDMQRLEQVINRRRKVKRDETLYRLNDKFDMLYAIRLGHFKTF 84 C CS+ QLC+P L++ ++ +L+ +I R++ +++ +TL++ D+ LYAIR G K++ Sbjct: 20 CQDCSISQLCIPFTLNEHELDQLDNIIERKKPIQKGQTLFKAGDELKSLYAIRSGTIKSY 79 Query: 85 QHNPNGGQQITGFQMAGELLGMDAIGAGHHLCEAVALEDSEVCEIPFASLEDLFRDMPTL 144 G +QITGF +AG+L+G DAIG+GHH A ALE S VCEIPF +L+DL MP L Sbjct: 80 TITEQGDEQITGFHLAGDLVGFDAIGSGHHPSFAQALETSMVCEIPFETLDDLSGKMPNL 139 Query: 145 LRQFHRMMSLEISREQRVMLTLGSMTAQQKMAAFLLNLSSRYMSRGYSSTRFQLRMTREE 204 +Q R+MS EI +Q ++L L A++++AAF+ NLS R+ RG+S F+L MTR + Sbjct: 140 RQQMMRLMSGEIKGDQDMILLLSKKNAEERLAAFIYNLSRRFAQRGFSPREFRLTMTRGD 199 Query: 205 IGNYLGLAVESVSRLLTNFKKSGVIEVNHRDVEL 238 IGNYLGL VE++SRLL F+KSG++ V + + + Sbjct: 200 IGNYLGLTVETISRLLGRFQKSGMLAVKGKYITI 233 >Zfnr [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases EcZ Escherichia coli O157:H7 EDL933 Length = 250 Score = 208 bits (530), Expect = 7e-54, Method: Compositional matrix adjust. Identities = 98/214 (45%), Positives = 147/214 (68%) Query: 25 CSACSMHQLCLPMGLDQGDMQRLEQVINRRRKVKRDETLYRLNDKFDMLYAIRLGHFKTF 84 C CS+ QLC+P L++ ++ +L+ +I R++ +++ +TL++ D+ LYAIR G K++ Sbjct: 20 CQDCSISQLCIPFTLNEHELDQLDNIIERKKPIQKGQTLFKAGDELKSLYAIRSGTIKSY 79 Query: 85 QHNPNGGQQITGFQMAGELLGMDAIGAGHHLCEAVALEDSEVCEIPFASLEDLFRDMPTL 144 G +QITGF +AG+L+G DAIG+GHH A ALE S VCEIPF +L+DL MP L Sbjct: 80 TITEQGDEQITGFHLAGDLVGFDAIGSGHHPSFAQALETSMVCEIPFETLDDLSGKMPNL 139 Query: 145 LRQFHRMMSLEISREQRVMLTLGSMTAQQKMAAFLLNLSSRYMSRGYSSTRFQLRMTREE 204 +Q R+MS EI +Q ++L L A++++AAF+ NLS R+ RG+S F+L MTR + Sbjct: 140 RQQMMRLMSGEIKGDQDMILLLSKKNAEERLAAFIYNLSRRFAQRGFSPREFRLTMTRGD 199 Query: 205 IGNYLGLAVESVSRLLTNFKKSGVIEVNHRDVEL 238 IGNYLGL VE++SRLL F+KSG++ V + + + Sbjct: 200 IGNYLGLTVETISRLLGRFQKSGMLAVKGKYITI 233 >ECs1915 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Ecs Escherichia coli O157:H7 Length = 250 Score = 208 bits (530), Expect = 7e-54, Method: Compositional matrix adjust. Identities = 98/214 (45%), Positives = 147/214 (68%) Query: 25 CSACSMHQLCLPMGLDQGDMQRLEQVINRRRKVKRDETLYRLNDKFDMLYAIRLGHFKTF 84 C CS+ QLC+P L++ ++ +L+ +I R++ +++ +TL++ D+ LYAIR G K++ Sbjct: 20 CQDCSISQLCIPFTLNEHELDQLDNIIERKKPIQKGQTLFKAGDELKSLYAIRSGTIKSY 79 Query: 85 QHNPNGGQQITGFQMAGELLGMDAIGAGHHLCEAVALEDSEVCEIPFASLEDLFRDMPTL 144 G +QITGF +AG+L+G DAIG+GHH A ALE S VCEIPF +L+DL MP L Sbjct: 80 TITEQGDEQITGFHLAGDLVGFDAIGSGHHPSFAQALETSMVCEIPFETLDDLSGKMPNL 139 Query: 145 LRQFHRMMSLEISREQRVMLTLGSMTAQQKMAAFLLNLSSRYMSRGYSSTRFQLRMTREE 204 +Q R+MS EI +Q ++L L A++++AAF+ NLS R+ RG+S F+L MTR + Sbjct: 140 RQQMMRLMSGEIKGDQDMILLLSKKNAEERLAAFIYNLSRRFAQRGFSPREFRLTMTRGD 199 Query: 205 IGNYLGLAVESVSRLLTNFKKSGVIEVNHRDVEL 238 IGNYLGL VE++SRLL F+KSG++ V + + + Sbjct: 200 IGNYLGLTVETISRLLGRFQKSGMLAVKGKYITI 233 >PA1544 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Pae Pseudomonas aeruginosa Length = 244 Score = 201 bits (512), Expect = 9e-52, Method: Compositional matrix adjust. Identities = 102/237 (43%), Positives = 153/237 (64%), Gaps = 1/237 (0%) Query: 16 VNLHAL-RASCSACSMHQLCLPMGLDQGDMQRLEQVINRRRKVKRDETLYRLNDKFDMLY 74 + + AL +A C CS+ LCLP+ L DM L++++ R R +K+ E L+R D F ++ Sbjct: 5 IKVRALPQAHCKDCSLAPLCLPLSLTVEDMDSLDEIVKRGRPLKKGEFLFRQGDPFGSVF 64 Query: 75 AIRLGHFKTFQHNPNGGQQITGFQMAGELLGMDAIGAGHHLCEAVALEDSEVCEIPFASL 134 A+R G KTF G +QITGF + EL+G+ + + A ALE + VCEIPF L Sbjct: 65 AVRSGALKTFSITDAGEEQITGFHLPSELVGLSGMDTETYPVSAQALETTSVCEIPFERL 124 Query: 135 EDLFRDMPTLLRQFHRMMSLEISREQRVMLTLGSMTAQQKMAAFLLNLSSRYMSRGYSST 194 ++L +P L RQ R+MS EI +Q++ML L TA +++A FL+NLS+R+ +RG+S+ Sbjct: 125 DELSEQLPQLRRQLMRLMSREIRDDQQMMLLLSKKTADERIATFLVNLSARFRARGFSAQ 184 Query: 195 RFQLRMTREEIGNYLGLAVESVSRLLTNFKKSGVIEVNHRDVELCDLPTLRAVALGN 251 +F+L M+R EIGNYLGLAVE+VSR+ T F+++G+I ++V + D L A+A G Sbjct: 185 QFRLAMSRNEIGNYLGLAVETVSRVFTRFQQNGLISAEGKEVHILDSIELCALAGGQ 241 >HI1425 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Hin Haemophilus influenzae Length = 257 Score = 200 bits (508), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 96/220 (43%), Positives = 146/220 (66%) Query: 25 CSACSMHQLCLPMGLDQGDMQRLEQVINRRRKVKRDETLYRLNDKFDMLYAIRLGHFKTF 84 C CS+ QLC+P L++ ++ +L+ +I R++ +++ + L++ D + +YAIR G K++ Sbjct: 23 CQDCSISQLCIPFTLNEQELDQLDNIIERKKPIQKSQVLFKAGDSLNSIYAIRSGTIKSY 82 Query: 85 QHNPNGGQQITGFQMAGELLGMDAIGAGHHLCEAVALEDSEVCEIPFASLEDLFRDMPTL 144 + +G +QIT F + G+L+G DAI H A ALE + VCEIPF L+DL MP L Sbjct: 83 TISESGEEQITSFHLPGDLVGFDAITQMQHPSFAQALETAMVCEIPFDILDDLAGKMPKL 142 Query: 145 LRQFHRMMSLEISREQRVMLTLGSMTAQQKMAAFLLNLSSRYMSRGYSSTRFQLRMTREE 204 +Q R+MS EI +Q ++L L M A++++AAF+ NLS RY +RG+S+ F+L MTR + Sbjct: 143 RQQILRLMSSEIKSDQEMILLLSKMNAEERLAAFIHNLSKRYSARGFSAREFRLTMTRGD 202 Query: 205 IGNYLGLAVESVSRLLTNFKKSGVIEVNHRDVELCDLPTL 244 IGNYLGL VE++SRLL F+K GVI V + + + DL L Sbjct: 203 IGNYLGLTVETISRLLGRFQKLGVISVQGKYITINDLNGL 242