BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0029.0339.p (208 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2047 [LR] COG0494 NTP pyrophosphohydrolases including oxidati... 238 5e-63 TM1181 [LR] COG0494 NTP pyrophosphohydrolases including oxidativ... 139 3e-33 lin2079 [LR] COG0494 NTP pyrophosphohydrolases including oxidati... 131 9e-31 BH1524 [LR] COG0494 NTP pyrophosphohydrolases including oxidativ... 131 1e-30 BS_yqkG [LR] COG0494 NTP pyrophosphohydrolases including oxidati... 130 2e-30 SA1330 [LR] COG0494 NTP pyrophosphohydrolases including oxidativ... 127 1e-29 NMB1064 [LR] COG0494 NTP pyrophosphohydrolases including oxidati... 121 1e-27 NMA1263 [LR] COG0494 NTP pyrophosphohydrolases including oxidati... 116 4e-26 SP0989 [LR] COG0494 NTP pyrophosphohydrolases including oxidativ... 109 4e-24 VCA0764 [LR] COG0494 NTP pyrophosphohydrolases including oxidati... 108 7e-24 >RSc2047 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes Rso Ralstonia solanacearum Length = 205 Score = 238 bits (608), Expect = 5e-63, Method: Compositional matrix adjust. Identities = 112/183 (61%), Positives = 140/183 (76%) Query: 19 DAHLKETQKDNRQVYTGHFLKVQQDTVILPDGKHAVREYIKHPGAVAVLPLFDDGSVLME 78 DA L+ETQ + V+ G FL ++QD V LPDG++A REY+ HPGAV ++PLFDDG+VLME Sbjct: 20 DAGLRETQLASALVHQGKFLTLKQDVVRLPDGRNASREYLIHPGAVMMIPLFDDGTVLME 79 Query: 79 RQFRYPLHRVFIEFPAGKIDPGEDTLDCAKRELQEETGYTAAQWQYVCTIHNAIAYSDEH 138 RQFRYP+ +V IEFPAGK+DP E L C KREL+EETGY A +W ++ IH I+YS E Sbjct: 80 RQFRYPVGKVMIEFPAGKLDPREGALACGKRELREETGYVAQRWDFLTRIHPVISYSTEF 139 Query: 139 LVLYVARGLTQGERKLDEGEFLDIYKAPLEELVEQVRNGEITDVKTVIGVFWLEKILSGA 198 + LY+AR L GE LDEGEFL+ + AP +L++ VR G I+DVKT+IGVFWLEKILSG Sbjct: 140 IDLYLARDLQPGESALDEGEFLETFIAPAGQLIDWVRTGRISDVKTIIGVFWLEKILSGT 199 Query: 199 WTP 201 WTP Sbjct: 200 WTP 202 >TM1181 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes Tma Thermotoga maritima Length = 179 Score = 139 bits (351), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 66/172 (38%), Positives = 107/172 (62%), Gaps = 3/172 (1%) Query: 24 ETQKDNRQVYTGHFLKVQQDTVILPDGKHAVREYIKHPGAVAVLPLFDDGSVLMERQFRY 83 E + D+++V+ G + V+ D V LPDG+ + RE + HPGAV ++P+ G +L Q+RY Sbjct: 5 EEKIDSKRVFEGKMISVRVDRVRLPDGRESTREVVDHPGAVVIVPVLG-GKILFVEQYRY 63 Query: 84 PLHRVFIEFPAGKIDPGEDTLDCAKRELQEETGYTAAQWQYVCTIHNAIAYSDEHLVLYV 143 P+ +V +E PAGK+DPGE +CAKREL+EETGY A + Y+ I ++ E + ++ Sbjct: 64 PIEQVLLELPAGKLDPGESPEECAKRELEEETGYRAKKLSYLGKIFTTPGFTTEVIHIFA 123 Query: 144 ARGLTQGERKLDEGEFLDIYKAPLEELVEQVRNGEITDVKTVIGV--FWLEK 193 A L + + D EF+++ + P+EE + ++N EI D KT+ + F+ K Sbjct: 124 AEDLEKTSQNTDPDEFIEVKEVPIEEALSLLKNAEIEDSKTICALTRFFFAK 175 >lin2079 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes Lin Listeria innocua Length = 185 Score = 131 bits (330), Expect = 9e-31, Method: Compositional matrix adjust. Identities = 70/181 (38%), Positives = 113/181 (62%), Gaps = 4/181 (2%) Query: 18 MDAHLKETQKDNRQVYTGHFLKVQQDTVILPDGKHAVREYIKHPGAVAVLPLFDDGSVLM 77 MD+ L+E ++++G+ +++Q D V LP+G+ + RE +KHPGAVA++P DG + + Sbjct: 1 MDS-LEEKTLHTEKIFSGNVIELQVDDVELPNGEKSKREIVKHPGAVAIIPFSADGRMYL 59 Query: 78 ERQFRYPLHRVFIEFPAGKIDPGEDTLDCAKRELQEETGYTAAQWQYVCTIHNAIAYSDE 137 QFR PL + IE PAGK++PGED L AKREL+EETG+ + Y+ + + + ++ E Sbjct: 60 VEQFRKPLEKNIIEIPAGKMEPGEDPLVTAKRELEEETGFQSDDLTYLTSFYTSPGFASE 119 Query: 138 HLVLYVARGLTQGERKL--DEGEFLDIYKAPLEELVEQVRNGEITDVKTVIGV-FWLEKI 194 L +YVAR L + E L D EF+++ K +EE + + I D KT+ + +W ++ Sbjct: 120 LLHIYVARDLRKMEHPLAQDADEFINLVKVTMEEAEQLIAQQFIHDAKTMYAIQYWKLQL 179 Query: 195 L 195 L Sbjct: 180 L 180 >BH1524 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes Bha Bacillus halodurans Length = 183 Score = 131 bits (329), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 70/175 (40%), Positives = 111/175 (63%) Query: 18 MDAHLKETQKDNRQVYTGHFLKVQQDTVILPDGKHAVREYIKHPGAVAVLPLFDDGSVLM 77 M +E +++G + +Q D V LP+GK + RE +KHPGAVAV+P+ +DG +++ Sbjct: 1 MSQSFEEKTIKTTPIFSGRIIDLQVDEVELPNGKTSTRELVKHPGAVAVIPVTEDGKLVL 60 Query: 78 ERQFRYPLHRVFIEFPAGKIDPGEDTLDCAKRELQEETGYTAAQWQYVCTIHNAIAYSDE 137 RQFR L + +E PAGK++ GED L CA+REL+EETGY A Q ++ + + + ++DE Sbjct: 61 VRQFRKALEKEILEIPAGKLEKGEDPLVCAERELEEETGYAAKQLTFLRSFYTSPGFADE 120 Query: 138 HLVLYVARGLTQGERKLDEGEFLDIYKAPLEELVEQVRNGEITDVKTVIGVFWLE 192 + LY+A L +G DE EF+++ + L+E ++ + N I D KTV V +L+ Sbjct: 121 IIYLYLAEQLIEGVAHTDEDEFVEVVEVTLDEALQYMENERIHDAKTVFAVQYLQ 175 >BS_yqkG [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes Bsu Bacillus subtilis Length = 185 Score = 130 bits (327), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 65/173 (37%), Positives = 111/173 (64%), Gaps = 2/173 (1%) Query: 22 LKETQKDNRQVYTGHFLKVQQDTVILPDGKHAVREYIKHPGAVAVLPLFDDGSVLMERQF 81 L+E Q+++G + + + V LP+GK + RE +KHPGAVAVL + D+G ++M +QF Sbjct: 4 LEEKTIAKEQIFSGKVIDLYVEDVELPNGKASKREIVKHPGAVAVLAVTDEGKIIMVKQF 63 Query: 82 RYPLHRVFIEFPAGKIDPGEDTLDCAKRELQEETGYTAAQWQYVCTIHNAIAYSDEHLVL 141 R PL R +E PAGK++ GE+ A REL+EETGYTA + + + + ++DE + + Sbjct: 64 RKPLERTIVEIPAGKLEKGEEPEYTALRELEEETGYTAKKLTKITAFYTSPGFADEIVHV 123 Query: 142 YVARGLT--QGERKLDEGEFLDIYKAPLEELVEQVRNGEITDVKTVIGVFWLE 192 ++A L+ + +R+LDE EF+++ + LE+ ++ V + E+ D KT + +L+ Sbjct: 124 FLAEELSVLEEKRELDEDEFVEVMEVTLEDALKLVESREVYDAKTAYAIQYLQ 176 >SA1330 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes Sau Staphylococcus aureus N315 Length = 180 Score = 127 bits (320), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 64/170 (37%), Positives = 100/170 (58%) Query: 22 LKETQKDNRQVYTGHFLKVQQDTVILPDGKHAVREYIKHPGAVAVLPLFDDGSVLMERQF 81 L E D +Y G + V+ TV LP+G+ + RE + H GAVAV L V++ +Q+ Sbjct: 3 LNEKTIDRTVIYNGKIVDVEIHTVTLPNGETSTRELVYHNGAVAVCALTPKKEVVLVKQY 62 Query: 82 RYPLHRVFIEFPAGKIDPGEDTLDCAKRELQEETGYTAAQWQYVCTIHNAIAYSDEHLVL 141 R P+ + +E PAGK++ E+ ++ AKREL+EETGY A + +V ++ + + DE L + Sbjct: 63 RKPVEKPLLEIPAGKLEDDENRVEAAKRELEEETGYIAKELTHVVDMYGSPGFCDEQLSI 122 Query: 142 YVARGLTQGERKLDEGEFLDIYKAPLEELVEQVRNGEITDVKTVIGVFWL 191 Y L +G LDE EF+++ K P+E + + N EI D KT+I + L Sbjct: 123 YFTDNLEEGTVHLDEDEFVEVIKVPIENVKSMLMNKEIEDAKTIIALQHL 172 >NMB1064 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes Nme Neisseria meningitidis MC58 Length = 178 Score = 121 bits (304), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 67/175 (38%), Positives = 101/175 (57%), Gaps = 3/175 (1%) Query: 22 LKETQKDNRQVYTGHFLKVQQDTVILPDGKHAVREYIKHPGAVAVLPLFDDGSVLMERQF 81 L+E + +Y G F+ + +D V LP+G R I+HPGA VL + D+G V++ RQ+ Sbjct: 3 LREVKLGGETIYEGGFVSISRDKVRLPNGNEGQRIVIRHPGAACVLAVTDEGKVVLVRQW 62 Query: 82 RYPLHRVFIEFPAGKID-PGEDTLDCAKRELQEETGYTAAQWQYVCTIHNAIAYSDEHLV 140 RY ++ +E PAGK+D GED CA REL EET YTA + + + + A+ + +E + Sbjct: 63 RYAANQATLELPAGKLDVAGEDMAACALRELAEETPYTADSVRLLYSFYTAVGFCNEKMY 122 Query: 141 LYVARGLTQGER-KLDEGEFLDIYKAPLEELVEQVRNGEITDVKTVIGV-FWLEK 193 L+ A G+ G DE E + EE+ + + N EI D KT+IG+ +WL K Sbjct: 123 LFEAEGVRLGSTLANDEDEITETVLMSKEEVRQALANDEIKDGKTLIGLQYWLMK 177 >NMA1263 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes NmA Neisseria meningitidis Z2491 Length = 178 Score = 116 bits (290), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 65/175 (37%), Positives = 99/175 (56%), Gaps = 3/175 (1%) Query: 22 LKETQKDNRQVYTGHFLKVQQDTVILPDGKHAVREYIKHPGAVAVLPLFDDGSVLMERQF 81 L+E + +Y G F+ + +D V LP+G R I+HPGA VL + D+ V++ RQ+ Sbjct: 3 LREVKLGGETIYEGGFVSISRDKVRLPNGNEGQRIVIRHPGAACVLAVTDEEKVVLVRQW 62 Query: 82 RYPLHRVFIEFPAGKID-PGEDTLDCAKRELQEETGYTAAQWQYVCTIHNAIAYSDEHLV 140 RY ++ +E PAGK+D GED CA REL EET YT + + + + A+ + +E + Sbjct: 63 RYAANQATLELPAGKLDVAGEDMAACALRELAEETPYTTDSVRLLYSFYTAVGFCNEKMY 122 Query: 141 LYVARGLTQGER-KLDEGEFLDIYKAPLEELVEQVRNGEITDVKTVIGV-FWLEK 193 L+ A G+ G DE E + EE+ + + N EI D KT+IG+ +WL K Sbjct: 123 LFEAEGVRLGSTLANDEDEITETVLMSKEEVRQALANDEIKDGKTLIGLQYWLMK 177 >SP0989 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes Spn Streptococcus pneumoniae TIGR4 Length = 181 Score = 109 bits (273), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 67/176 (38%), Positives = 105/176 (59%), Gaps = 7/176 (3%) Query: 21 HLKETQKDNRQVYTGHFLKVQQDTVILPDGK-HAVREYIKHPGAVAVLPLFDDGSVLMER 79 +E +++Y G K+ QD V LP+GK A R+ I H GAV VL + D+ +++ + Sbjct: 2 EFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNGAVCVLAVTDEQKLILVK 61 Query: 80 QFRYPLHRVFIEFPAGKIDPGEDT--LDCAKRELQEETGYTAAQWQYVCTIHNAIAYSDE 137 Q+R + V E PAGK++ GE+T + A REL+EET YT + + + ++AI + +E Sbjct: 62 QYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT-GKLELLYDFYSAIGFCNE 120 Query: 138 HLVLYVARGLTQGE--RKLDEGEFLDIYKAPLEELVEQVRNGEITDVKTVIGV-FW 190 L LY+A LT+ E R DE E L++ + LEE E +++G I D KT++ V +W Sbjct: 121 KLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQSGHICDAKTIMAVQYW 176 >VCA0764 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes Vch Vibrio cholerae Length = 185 Score = 108 bits (270), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 57/166 (34%), Positives = 96/166 (57%), Gaps = 1/166 (0%) Query: 21 HLKETQKDNRQVYTGHFLKVQQDTVILPDGKHAVREYIKHPGAVAVLPLFDDGSVLMERQ 80 + +T ++ ++ + + ++ V+LP+G I HPGA +LPL D G +++ RQ Sbjct: 8 YFDKTHSMSKIIHQWKSIALVEEDVLLPNGHSVTHTTISHPGAAVILPLTDQGEIVVIRQ 67 Query: 81 FRYPLHRVFIEFPAGKIDPGEDTLDCAKRELQEETGYTAAQWQYVCTIHNAIAYSDEHLV 140 FR L + +E PAG I+ GE L CA+REL+EETG++A Q+ + + + DE Sbjct: 68 FRPSLKKWLLELPAGTIEEGEPPLSCAQRELEEETGFSAQQFIELGQVTPLAGFCDEIQH 127 Query: 141 LYVARGLTQGER-KLDEGEFLDIYKAPLEELVEQVRNGEITDVKTV 185 L+VA+ L++ R DE E +++ +EL ++ G+ITD KT+ Sbjct: 128 LFVAKNLSKTARYSCDEDEVIEVLFLTPQELERKIVFGDITDSKTI 173