BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0029.0305.p (500 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1187 [Q] COG3653 N-acyl-D-aspartate/D-glutamate deacylase Rso... 235 2e-61 PAB0090 [Q] COG3653 N-acyl-D-aspartate/D-glutamate deacylase Pab... 107 5e-23 CC3460 Non COG 97 9e-20 Rv2913c [Q] COG3653 N-acyl-D-aspartate/D-glutamate deacylase Mtu... 96 1e-19 MT2981 [Q] COG3653 N-acyl-D-aspartate/D-glutamate deacylase MtC ... 96 1e-19 lin1853 [F] COG1001 Adenine deaminase Lin Listeria innocua 65 4e-10 >RSp1187 [Q] COG3653 N-acyl-D-aspartate/D-glutamate deacylase Rso Ralstonia solanacearum Length = 494 Score = 235 bits (600), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 118/182 (64%), Positives = 141/182 (77%), Gaps = 8/182 (4%) Query: 12 RRCDILIRHALVIDGSGAEPVAA--DVAVHKGRVAAIGKLDD--WQAAQEIDASGRVLSP 67 ++ D +IR ++DGSG EP + DVA+ GR+AAI D W +E+D +GRVL+P Sbjct: 2 QQYDSVIRRVRIVDGSGHEPESTLFDVAIADGRIAAIATSDSTAWLGDEEVDGAGRVLAP 61 Query: 68 GFIDVHTHDDTNVIRTPEMFPKLSQGVTTVVVGNCGISAAPVTLKGEPPDPMNLLGKREA 127 GFIDVHTHDDTNVIRTP+M PK+SQG+TTV+VGNCGISA+P TL+GEPPDPMNLLG A Sbjct: 62 GFIDVHTHDDTNVIRTPDMLPKVSQGITTVIVGNCGISASPATLRGEPPDPMNLLGPAGA 121 Query: 128 FHYPSFASYVEAVNAARPAINVAALVGHTALRNNHMDRLDRAATESEIAGIYIYMRARAR 187 F YP+FASYVEAV ARPA+NVAALVGHTALRNNH+DRLDR AT E+ MRA+ R Sbjct: 122 FRYPTFASYVEAVEQARPAVNVAALVGHTALRNNHLDRLDRPATAPEVEA----MRAQLR 177 Query: 188 GA 189 A Sbjct: 178 EA 179 >PAB0090 [Q] COG3653 N-acyl-D-aspartate/D-glutamate deacylase Pab Pyrococcus abyssi Length = 526 Score = 107 bits (268), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 69/198 (34%), Positives = 104/198 (52%), Gaps = 11/198 (5%) Query: 13 RCDILIRHALVIDGSGAEPVAADVAVHKGRVAAIGKL-DDWQAAQEIDASGRVLSPGFID 71 DI+I++ ++DG+G D+ + G++ IGK+ +D Q IDAS +++PGFID Sbjct: 3 EYDIVIKNGKIVDGTGNPWFRTDIGIKDGKIVKIGKIKEDGQVT--IDASNLIVAPGFID 60 Query: 72 VHTHDDTNVIRTPEMFPKLSQGVTTVVVGNCGISAAPVTLKGEPPDPMN----LLGKREA 127 +H HDD + KL QGVTTVV GNCGIS APV E D + +LGK Sbjct: 61 MHAHDDLIFFKDRFNRAKLLQGVTTVVSGNCGISVAPVN--EEMLDVLKSYVGILGKEVE 118 Query: 128 FHYPSFASYVEAVNAARP-AINVAALVGHTALRNNHMDRLDRAATESEIAGI-YIYMRAR 185 F + S+ +++A+ P N LVGH LR M R TE E+ + + ++ Sbjct: 119 FKWRSYGEFLDALEEVGPLGTNFVGLVGHGTLRIAVMGMEARDPTEEELGRMKELLAKSM 178 Query: 186 ARGARAWRAGPVHRAGLW 203 GA +G ++ G++ Sbjct: 179 EEGAFGMSSGLIYPPGVY 196 >CC3460 Non COG Length = 581 Score = 97.1 bits (240), Expect = 9e-20, Method: Compositional matrix adjust. Identities = 57/164 (34%), Positives = 88/164 (53%), Gaps = 11/164 (6%) Query: 10 GERRCDILIRHALVIDGSGAEPVAADVAVHKGRVAAIGKLDDWQAAQEIDASGRVLSPGF 69 G+R D+++R +V DG+G ADV V G + A+GK A+EIDA GR+++PGF Sbjct: 2 GDRAYDLVLRSGVVFDGAGGPGFQADVGVRDGVIVAVGK-GLAAGAEEIDARGRIVTPGF 60 Query: 70 IDVHTHDDTNVIRTPEMFPKLSQGVTTVVVGNCGISAAPV----------TLKGEPPDPM 119 +D+HTH D + ++ P GVTTVV+GNCG+ AP ++G P Sbjct: 61 VDIHTHYDGQATWSGQLGPSSGHGVTTVVMGNCGVGFAPCRPDDHDRLIRLMEGVEDIPF 120 Query: 120 NLLGKREAFHYPSFASYVEAVNAARPAINVAALVGHTALRNNHM 163 +L + + + SF Y++ + ++V A + H ALR M Sbjct: 121 PVLTEGLPWAWESFPDYLDFLAGRAFDVDVGAQLPHAALRVYVM 164 >Rv2913c [Q] COG3653 N-acyl-D-aspartate/D-glutamate deacylase Mtu Mycobacterium tuberculosis H37Rv Length = 611 Score = 96.3 bits (238), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 67/201 (33%), Positives = 103/201 (51%), Gaps = 28/201 (13%) Query: 1 MLSTTHAADGERRC--DILIRHALVIDGSGAEPVAADVAVHKGRVAAI--GKLDDWQAAQ 56 ML+ D E D++IR L DG+G P+ + + G VA + G LD+ + Sbjct: 1 MLAWRQLNDLEETVTYDVIIRDGLWFDGTGNAPLTRTLGIRDGVVATVAAGALDETGCPE 60 Query: 57 EIDASGRVLSPGFIDVHTHDDTNVIRTPEMFPKLSQGVTTVVVGNCGISAAPVTLKGEPP 116 +DA+G+ + PGFIDVHTH D V+ P + + GVTTV++GNC +S T+ Sbjct: 61 VVDAAGKWVVPGFIDVHTHYDAEVLLDPGLRESVRHGVTTVLLGNCSLS----TVYANSE 116 Query: 117 DPMNLLGKREAF-------------HYPSFASYVEAVNAARPAINVAALVGHTALRNNHM 163 D +L + EA + + A Y+EA++A NV++L+GH+ LR + Sbjct: 117 DAADLFSRVEAVPREFVLGALRDNQTWSTPAEYIEAIDALPLGPNVSSLLGHSDLRTAVL 176 Query: 164 DRLDRAA------TESEIAGI 178 LDRA TE+E+A + Sbjct: 177 G-LDRATDDTVRPTEAELAKM 196 >MT2981 [Q] COG3653 N-acyl-D-aspartate/D-glutamate deacylase MtC Mycobacterium tuberculosis CDC1551 Length = 611 Score = 96.3 bits (238), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 67/201 (33%), Positives = 103/201 (51%), Gaps = 28/201 (13%) Query: 1 MLSTTHAADGERRC--DILIRHALVIDGSGAEPVAADVAVHKGRVAAI--GKLDDWQAAQ 56 ML+ D E D++IR L DG+G P+ + + G VA + G LD+ + Sbjct: 1 MLAWRQLNDLEETVTYDVIIRDGLWFDGTGNAPLTRTLGIRDGVVATVAAGALDETGCPE 60 Query: 57 EIDASGRVLSPGFIDVHTHDDTNVIRTPEMFPKLSQGVTTVVVGNCGISAAPVTLKGEPP 116 +DA+G+ + PGFIDVHTH D V+ P + + GVTTV++GNC +S T+ Sbjct: 61 VVDAAGKWVVPGFIDVHTHYDAEVLLDPGLRESVRHGVTTVLLGNCSLS----TVYANSE 116 Query: 117 DPMNLLGKREAF-------------HYPSFASYVEAVNAARPAINVAALVGHTALRNNHM 163 D +L + EA + + A Y+EA++A NV++L+GH+ LR + Sbjct: 117 DAADLFSRVEAVPREFVLGALRDNQTWSTPAEYIEAIDALPLGPNVSSLLGHSDLRTAVL 176 Query: 164 DRLDRAA------TESEIAGI 178 LDRA TE+E+A + Sbjct: 177 G-LDRATDDTVRPTEAELAKM 196 >lin1853 [F] COG1001 Adenine deaminase Lin Listeria innocua Length = 579 Score = 64.7 bits (156), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 42/127 (33%), Positives = 65/127 (51%), Gaps = 14/127 (11%) Query: 7 AADGERRCDILIRHALVIDGSGAEPVAADVAVHKGRVAAIGKLDDWQAAQEIDASGRVLS 66 +DG + D++I++ +++ E + D+A+ G +A IG D A Q IDA+G +S Sbjct: 13 VSDGRAKADLVIKNGRIVNVFSGEIMEGDIAIKNGYIAGIGHFPD--ADQIIDAAGEFIS 70 Query: 67 PGFIDVHTHDDTNVIRTPEMFPK--LSQGVTTVVV---------GNCGISAAPVTLKGEP 115 PGFID H H ++ ++ TP F + L GVTT++ G GI KG P Sbjct: 71 PGFIDAHVHVESAMV-TPSEFARVLLPNGVTTIITDPHEIANVAGEKGIEFMLEDAKGAP 129 Query: 116 PDPMNLL 122 D +L Sbjct: 130 LDMFVML 136