BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0029.0247.p (297 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA1145 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 219 8e-57 PA0289 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 187 2e-47 PA1422 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 182 1e-45 PA0133 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 151 2e-36 mlr6990 [K] COG0583 Transcriptional regulator Mlo Mesorhizobium ... 138 1e-32 RSp1574 [K] COG0583 Transcriptional regulator Rso Ralstonia sola... 108 1e-23 SMb21434 [K] COG0583 Transcriptional regulator Sme Sinorhizobium... 77 5e-14 Z2299 [K] COG0583 Transcriptional regulator EcZ Escherichia coli... 74 3e-13 ECs2027 [K] COG0583 Transcriptional regulator Ecs Escherichia co... 74 3e-13 ydcI [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 74 5e-13 >PA1145 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 300 Score = 219 bits (557), Expect = 8e-57, Method: Compositional matrix adjust. Identities = 127/295 (43%), Positives = 171/295 (57%), Gaps = 5/295 (1%) Query: 1 MLTNIFDLDLRLIRVFLAVVDSHGVSAAQARLNVGQSTISTQLNSLETRLGYRLCERGRA 60 ML N+ DLDLRL+R+F VV G +AAQA LN+ QS IS + SLE RLGYRLCERG+ Sbjct: 1 MLRNVTDLDLRLLRIFACVVKCGGFTAAQAELNMSQSNISMHIASLEKRLGYRLCERGKG 60 Query: 61 GFRLTAKGEKFADAARRMMDALDEFGMQARNLDKRLVGTLAIGLMGHTPAQHNHRLAEVI 120 GFRLTAKG + +A+R M DA+ F QA+ L RLVG L +GL + R + + Sbjct: 61 GFRLTAKGRRVLEASRTMFDAIGLFRDQAQALSGRLVGELYLGLADNLATLPQARFGDAL 120 Query: 121 RRFRQRDEAVRLELLVRTPGELEEMLLNGAIQVAIGYFWRRVTALHYTPLMLERQLAYCA 180 RF++RD+ V+L L V +P ELE ++ G + +AI YF R +L Y PL E +C Sbjct: 121 ARFQRRDQDVQLNLFVNSPTELELAVIEGELDLAISYFSRSRPSLEYRPLYREEIGVFCG 180 Query: 181 PPHPLFDQPGEIEPEQAAGYAWAWRDYPVPPEH--LPLQQRNIMAATGNMEAMSILILSG 238 HPLF E +P A W + PE+ LPL+ A +MEA++ +L+G Sbjct: 181 DRHPLF---AEAQPTLERIAACDWVMHGFLPENLVLPLRPSRSRATAYHMEAVAHAVLAG 237 Query: 239 QHLGYLPEEMGRQYEARGQMRALNRAKLAYDVGISVVTHRSRAREPIVAAFLDDL 293 HLGYLP + RG+MRAL +L+Y V S++ + R AF+DDL Sbjct: 238 THLGYLPTHYAEAWIERGRMRALLPERLSYPVEHSMIVYAGRPLSEAARAFIDDL 292 >PA0289 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 320 Score = 187 bits (476), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 117/304 (38%), Positives = 157/304 (51%), Gaps = 13/304 (4%) Query: 1 MLTNIFDLDLRLIRVFLAVVDSHGVSAAQARLNVGQSTISTQLNSLETRLGYRLCERGRA 60 ML NI D+DLR++R F A+V++ G +AAQARLN S +S + LE RLGY LC RG Sbjct: 5 MLGNINDIDLRMLRTFCAIVEAGGFTAAQARLNTSLSRLSVLVRDLEVRLGYSLCRRGNG 64 Query: 61 GFRLTAKGEKFADAARRMMDALDEFGMQARNLDKRLVGTLAIGLMGHTPAQHNHRLAEVI 120 GF+LT +G++ DAA + + F Q R L R L +G + QH L I Sbjct: 65 GFQLTEEGQELYDAALGLFSDIARFREQVRGLGGRDREALHLGCVDGVIGQHCLPLPLAI 124 Query: 121 RRFRQRDEAVRLELLVRTPGELEEMLLNGAIQVAIGYFWRRVTALHYTPLMLERQLAYCA 180 R FRQR V L+L R P ELE +L +Q+A+G F R++ L+Y PL E Q YC Sbjct: 125 RLFRQRAPEVLLKLHTRRPDELEHAVLEERLQLAVGAFHHRLSGLYYQPLFREEQNLYCG 184 Query: 181 PPHPLF----DQP--GEIEPEQAAGYAWAWRDYPVPPEHLPLQQR-NIMAATGNMEAMSI 233 HP F D+P GEI G + + H P R N MEA++ Sbjct: 185 SAHPFFARADDEPTLGEICAADYVGRGY------MAENHRPHDLRFNQGTDAYTMEAIAT 238 Query: 234 LILSGQHLGYLPEEMGRQYEARGQMRALNRAKLAYDVGISVVTHRSRAREPIVAAFLDDL 293 L+ SG ++GYLP + A G+MRA+ +LAYD +T + P + FL L Sbjct: 239 LVFSGTYIGYLPTHYAATWVAEGRMRAIRPRQLAYDSEFHCITRQGHEERPTLTLFLRSL 298 Query: 294 KHAQ 297 AQ Sbjct: 299 FEAQ 302 >PA1422 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 297 Score = 182 bits (461), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 115/289 (39%), Positives = 157/289 (54%), Gaps = 7/289 (2%) Query: 9 DLRLIRVFLAVVDSHGVSAAQARLNVGQSTISTQLNSLETRLGYRLCERGRAGFRLTAKG 68 DLRL+R+F AVV G +AAQ LN+ S IST ++ LE +LG LC RGR GF LT+KG Sbjct: 7 DLRLLRIFAAVVRHQGFAAAQQELNLSTSAISTYMSQLENQLGIVLCHRGRGGFSLTSKG 66 Query: 69 EKFADAARRMMDALDEFGMQARNLDKRLVGTLAIGLMGHTPAQHNHRLAEVIRRFRQRDE 128 E F R++ L+ F A L L GTL +G++ T + LAEVI F + Sbjct: 67 ELFHQETLRILGELEGFERYALALKGELRGTLNLGVLDSTVSDPALPLAEVIGAFSREHP 126 Query: 129 AVRLELLVRTPGELEEMLLNGAIQVAIGYFWRRVTALHYTPLMLERQLAYCAPPHPLFDQ 188 AV L LLV++P EL+ +L +AIG F R+ L Y PL E+ YC+ HPLFD Sbjct: 127 AVHLHLLVQSPYELQLSVLENRQDLAIGAFSSRMNGLVYQPLYREQHWLYCSDRHPLFDG 186 Query: 189 ---PGEIEPEQAAGYAWAWRDYPVPPEHLPLQQRNIMAATGNMEAMSILILSGQHLGYLP 245 P ++ +Q R Y E ++ +MEA ILILSG ++GYLP Sbjct: 187 RRIPADLITQQRM----VGRGYWSQAELARHGFKHSAGTVESMEAQLILILSGGYIGYLP 242 Query: 246 EEMGRQYEARGQMRALNRAKLAYDVGISVVTHRSRAREPIVAAFLDDLK 294 E + +G++RAL A Y S++ R R+REP++ AF D L+ Sbjct: 243 EHYAHPWVEQGRLRALLPATFGYQAPFSLILRRGRSREPLIQAFRDQLR 291 >PA0133 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 305 Score = 151 bits (382), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 90/292 (30%), Positives = 152/292 (52%), Gaps = 2/292 (0%) Query: 2 LTNIFDLDLRLIRVFLAVVDSHGVSAAQARLNVGQSTISTQLNSLETRLGYRLCERGRAG 61 L + D D+RL+R+F +V+ SAA++ L + +S IS + LE RLG RLC+RGRAG Sbjct: 9 LGQVSDFDIRLLRIFKTIVECGSFSAAESTLGLSRSAISLHMGDLEKRLGMRLCQRGRAG 68 Query: 62 FRLTAKGEKFADAARRMMDALDEFGMQARNLDKRLVGTLAIGLMGHTPAQHNHRLAEVIR 121 F LT +G + A + ++ AL+ F + +L + L G L IG++ + R+ + Sbjct: 69 FALTDEGREVYRATQTLLAALEGFRAEVNDLHQHLRGELNIGIINNLVTLPQMRITHALS 128 Query: 122 RFRQRDEAVRLELLVRTPGELEEMLLNGAIQVAIGYFWRRVTALHYTPLMLERQLAYCAP 181 + + VR+ + + TP E+E +L+G + V + ++ L Y PL E YC+ Sbjct: 129 ALKGQGPQVRINIGMTTPNEIELGVLDGHLHVGVVPLISPLSGLEYLPLYDEHAQLYCSR 188 Query: 182 PHPLFDQP-GEIEPEQAAGYAWAWRDYPVPPE-HLPLQQRNIMAATGNMEAMSILILSGQ 239 H LF++ G+I ++ Y +P E Q+ N A+ + E M+ LIL+G Sbjct: 189 GHALFERADGDIAVDEVLAADAVAPSYRLPAEAQARHQELNNSASASDREGMAFLILTGN 248 Query: 240 HLGYLPEEMGRQYEARGQMRALNRAKLAYDVGISVVTHRSRAREPIVAAFLD 291 +GYLP + A G +R L + Y + +++VT + R ++ FL+ Sbjct: 249 FIGYLPSHYAADWVAAGMLRPLLPERFHYAIALTIVTRKGRRPNLVLERFLE 300 >mlr6990 [K] COG0583 Transcriptional regulator Mlo Mesorhizobium loti Length = 299 Score = 138 bits (348), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 84/269 (31%), Positives = 132/269 (49%), Gaps = 1/269 (0%) Query: 9 DLRLIRVFLAVVDSHGVSAAQARLNVGQSTISTQLNSLETRLGYRLCERGRAGFRLTAKG 68 DL L RVF +VV + G++AAQ L++ Q T+S L +LE RLG +LCERGR GF LT +G Sbjct: 7 DLHLFRVFESVVRNGGMTAAQMELSLSQPTVSNHLTALEQRLGVKLCERGRRGFSLTEEG 66 Query: 69 EKFADAARRMMDALDEFGMQARNLDKRLVGTLAIGLMGHTPAQHNHRLAEVIRRFRQRDE 128 + + + + LD + + L G + +G++ + RLA+ I + Sbjct: 67 RRVYEISMEITGMLDAGSARLSRVRSALAGKVGVGIVDCLATDPSFRLADAIAELSKAAP 126 Query: 129 AVRLELLVRTPGELEEMLLNGAIQVAIGYFWRRVTALHYTPLMLERQLAYCAPPHPLFDQ 188 + L+L + P ++ + + I + IG +V ++ Y L E +C HPLF + Sbjct: 127 EIELDLKIMRPNDITKAVAENEIDIGIGGSDIKVASVQYQILYHEEHAVFCGSSHPLFRR 186 Query: 189 PGE-IEPEQAAGYAWAWRDYPVPPEHLPLQQRNIMAATGNMEAMSILILSGQHLGYLPEE 247 E I + G+ W R Y T ++EA +++LSG +LG LP Sbjct: 187 NDETITSAECYGHPWVERGYWYGIRRHRFDTAASNRVTFDIEAQLLMVLSGAYLGVLPIH 246 Query: 248 MGRQYEARGQMRALNRAKLAYDVGISVVT 276 R +E +G++R L A AY I V T Sbjct: 247 FARVFEQQGRLRRLPLADEAYSADIDVAT 275 >RSp1574 [K] COG0583 Transcriptional regulator Rso Ralstonia solanacearum Length = 302 Score = 108 bits (271), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 76/271 (28%), Positives = 130/271 (47%), Gaps = 11/271 (4%) Query: 10 LRLIRVFLAVVDSHGVSAAQARLNVGQSTISTQLNSLETRLGYRLCERGRAGFRLTAKGE 69 LR +R+F AV ++G +AA+ +LN+ +++IS + +E LG RLCERG +GF LTA G Sbjct: 13 LRSLRIFCAVAQANGFAAAEKQLNMSKASISRHIREVEDHLGVRLCERGPSGFELTAAGR 72 Query: 70 KFADAARRMMDALDEFGMQARNLDKRLVGTLAIGLMGHTPAQHNHRLAEVIRRFRQRDEA 129 D AR + +L+ G + + L GTL IG+ + R++E + R+ Sbjct: 73 VALDLARDALKSLERIGPEIDAVRGVLSGTLTIGMSEQIMQHEDFRMSEALAALREEAPG 132 Query: 130 VRLELLVRTPGELEEMLLNGAIQVAIGYFWRRVTALHYTPLMLERQLAYCAPPHPLFDQP 189 VR+EL V EL L +Q+A+ ++ + +Y L ERQ Y A + ++P Sbjct: 133 VRVELAVMAFAELTLALRERRVQIAVRGMYKHDSGFNYLCLFNERQRVYTARHN--INRP 190 Query: 190 GEIEPEQAAGYAWAWRDYPVPPEHLPLQQRNIMAATGNMEAMSILILSGQHLGYLPEEMG 249 + +R P + L + + +EA+++ + +G ++G LPE Sbjct: 191 RRL--------PLVYRQQPFVHDALSVHGFSRGPEATGLEAVAMFVATGHYVGLLPEHYA 242 Query: 250 RQYEARGQMRALNRAKLAYDVGISVVTHRSR 280 R + L + YD + +T +R Sbjct: 243 DTVSHRYALVPLPDGPV-YDNKMCAITETAR 272 >SMb21434 [K] COG0583 Transcriptional regulator Sme Sinorhizobium meliloti Length = 306 Score = 77.0 bits (188), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 68/280 (24%), Positives = 120/280 (42%), Gaps = 13/280 (4%) Query: 7 DLDLRLIRVFLAVVDSHGVSAAQARLNVGQSTISTQLNSLETRLGYRLCERGRAGFRLTA 66 DL+L L+R F + + ++ A ARLN+ Q ++S L LE +L +L RG F LTA Sbjct: 4 DLNLNLLRSFFMIAEERSLTRAAARLNMSQPSVSQALQRLEEQLACQLVLRGSRKFELTA 63 Query: 67 KGEKFADAARRMMDALDEFGMQARNLDKRLVGTLAIGLMGHTPAQHNHRLAEVIRRFRQR 126 +G+K + + A++ G + G + I ++ + + + E +R + QR Sbjct: 64 RGQKIYEECGEIFRAVERIGQLTQERTAEEFGEVRIQIISNL---ESPLINEALRLYHQR 120 Query: 127 DEAVRLELLVRTPGELEEMLLNGAIQVAIGYFWRRVTALHYTPLMLERQLAYCAPPHPLF 186 +V + V+ + + + + + R V +L+ L E YC HPLF Sbjct: 121 FPSVTWVMEVQNSQDTVKRIQTEKCGIGLCLLSRPVFSLNCQLLFREEFSVYCGAEHPLF 180 Query: 187 D----QPGEIEPEQAAGYAWAWRDYPVPP-----EHLPLQQRNIMAATGNMEAMSILILS 237 + E+ E + A + P + L L +R I + N+E + +I++ Sbjct: 181 GRKEVEKRELRQESFVSFTCATEGMGLEPMAVLSQSLGLGER-ISGQSPNLEEVRRMIVA 239 Query: 238 GQHLGYLPEEMGRQYEARGQMRALNRAKLAYDVGISVVTH 277 G +G LP A G + L + +VTH Sbjct: 240 GLGIGILPLTAVHDEVASGLLWPLEIKGYPLGADVFLVTH 279 >Z2299 [K] COG0583 Transcriptional regulator EcZ Escherichia coli O157:H7 EDL933 Length = 354 Score = 74.3 bits (181), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 59/186 (31%), Positives = 84/186 (45%), Gaps = 15/186 (8%) Query: 10 LRLIRVFLAVVDSHGVSAAQARLNVGQSTISTQLNSLETRLGYRLCERGRAGFRLTAKGE 69 LR + F+AV + A LN+ Q +S LN LE G RL ERGR G +LT GE Sbjct: 60 LRHLHTFVAVAQQGTLGRAAETLNLSQPALSKTLNELEQLTGARLFERGRQGAQLTLPGE 119 Query: 70 KFADAARRMMDALDEFGM-----QARNLDKRLVGTLAIGLMGHTPAQHNHRLAEVIRRFR 124 +F A R++DA++ G + N D VG L +G P+ VI +F Sbjct: 120 QFLTHAVRVLDAINTAGQSLHRKEGPNNDVVRVGALPTAALGILPS--------VIGQFH 171 Query: 125 QRDEAVRLELLVRTPGELEEMLLNGAIQVAIGYFW--RRVTALHYTPLMLERQLAYCAPP 182 Q+ + L++ + + L G I + IG +T L+Y L LE P Sbjct: 172 QQQKETTLQVATMSNPMILAGLKTGEIDIGIGRMSDPELMTGLNYELLFLESLKLVVRPN 231 Query: 183 HPLFDQ 188 HPL + Sbjct: 232 HPLLQE 237 >ECs2027 [K] COG0583 Transcriptional regulator Ecs Escherichia coli O157:H7 Length = 354 Score = 74.3 bits (181), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 59/186 (31%), Positives = 84/186 (45%), Gaps = 15/186 (8%) Query: 10 LRLIRVFLAVVDSHGVSAAQARLNVGQSTISTQLNSLETRLGYRLCERGRAGFRLTAKGE 69 LR + F+AV + A LN+ Q +S LN LE G RL ERGR G +LT GE Sbjct: 60 LRHLHTFVAVAQQGTLGRAAETLNLSQPALSKTLNELEQLTGARLFERGRQGAQLTLPGE 119 Query: 70 KFADAARRMMDALDEFGM-----QARNLDKRLVGTLAIGLMGHTPAQHNHRLAEVIRRFR 124 +F A R++DA++ G + N D VG L +G P+ VI +F Sbjct: 120 QFLTHAVRVLDAINTAGQSLHRKEGPNNDVVRVGALPTAALGILPS--------VIGQFH 171 Query: 125 QRDEAVRLELLVRTPGELEEMLLNGAIQVAIGYFW--RRVTALHYTPLMLERQLAYCAPP 182 Q+ + L++ + + L G I + IG +T L+Y L LE P Sbjct: 172 QQQKETTLQVATMSNPMILAGLKTGEIDIGIGRMSDPELMTGLNYELLFLESLKLVVRPN 231 Query: 183 HPLFDQ 188 HPL + Sbjct: 232 HPLLQE 237 >ydcI [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 Length = 354 Score = 73.6 bits (179), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 59/186 (31%), Positives = 84/186 (45%), Gaps = 15/186 (8%) Query: 10 LRLIRVFLAVVDSHGVSAAQARLNVGQSTISTQLNSLETRLGYRLCERGRAGFRLTAKGE 69 LR + F+AV + A LN+ Q +S LN LE G RL ERGR G +LT GE Sbjct: 60 LRHLHTFVAVAQQGTLGRAAETLNLSQPALSKTLNELEQLTGARLFERGRQGAQLTLPGE 119 Query: 70 KFADAARRMMDALDEFG-----MQARNLDKRLVGTLAIGLMGHTPAQHNHRLAEVIRRFR 124 +F A R++DA++ G + N D VG L +G P+ VI +F Sbjct: 120 QFLTHAVRVLDAINTAGRSLHRKEGLNNDVVRVGALPTAALGILPS--------VIGQFH 171 Query: 125 QRDEAVRLELLVRTPGELEEMLLNGAIQVAIGYFW--RRVTALHYTPLMLERQLAYCAPP 182 Q+ + L++ + + L G I + IG +T L+Y L LE P Sbjct: 172 QQQKETTLQVATMSNPMILAGLKTGEIDIGIGRMSDPELMTGLNYELLFLESLKLVVRPN 231 Query: 183 HPLFDQ 188 HPL + Sbjct: 232 HPLLQE 237