BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0029.0231.p (834 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value VC1397 [NT] COG0643 Chemotaxis protein histidine kinase and rela... 389 e-107 HP0392_1 [NT] COG0643 Chemotaxis protein histidine kinase and re... 319 1e-86 jhp0989_1 [NT] COG0643 Chemotaxis protein histidine kinase and r... 310 8e-84 TM0702 [NT] COG0643 Chemotaxis protein histidine kinase and rela... 305 4e-82 PH0484 [NT] COG0643 Chemotaxis protein histidine kinase and rela... 298 4e-80 PAB1332 [NT] COG0643 Chemotaxis protein histidine kinase and rel... 294 5e-79 Cj0284c_1 [NT] COG0643 Chemotaxis protein histidine kinase and r... 294 5e-79 PA1458 [NT] COG0643 Chemotaxis protein histidine kinase and rela... 290 1e-77 CC0594 [NT] COG0643 Chemotaxis protein histidine kinase and rela... 283 2e-75 VC2063 [NT] COG0643 Chemotaxis protein histidine kinase and rela... 280 8e-75 >VC1397 [NT] COG0643 Chemotaxis protein histidine kinase and related kinases Vch Vibrio cholerae Length = 761 Score = 389 bits (998), Expect = e-107, Method: Compositional matrix adjust. Identities = 190/389 (48%), Positives = 286/389 (73%), Gaps = 3/389 (0%) Query: 446 KSVKVEQVKIDRLMNLIGEMVVSKNALPYLAQRAEDQFGVRELAREIKAQYAVINRIAEE 505 K++KV+Q K+D LM+L+GE++V+KN++ YLA RAE++FGVR+LA++IKA+ +VI+R+AE+ Sbjct: 370 KTLKVDQEKVDLLMDLVGELIVAKNSMQYLAYRAENEFGVRKLAQDIKAEQSVISRLAED 429 Query: 506 MQDAIMQVRMMPVSVVFQRFPRLVRDISRKLGKEVQLVLVGEETEADKNIIEALADPLIH 565 +Q +MQVRM+P++ VFQR+PRL+RDISRKLGK+V L++ GE+TEADK+I+E L++PL+H Sbjct: 430 LQSVVMQVRMVPLATVFQRYPRLIRDISRKLGKQVDLIIEGEDTEADKSIVEDLSEPLVH 489 Query: 566 IVRNSLDHGLEGPEQRRASGKPALGSLTISAAHEGDQVVIVIEDDGKGIDPALIKRKAYE 625 ++RN+LDHG+E P+ RR GK G +T+SA D V+I + DDGKG+D +K KA E Sbjct: 490 LIRNALDHGIESPDIRREQGKNPTGKITLSAFTLDDSVIIKMSDDGKGVDVERVKTKALE 549 Query: 626 KGLIDEAQLERISDQDAVNLVFSSGFSTAEVVSDLSGRGVGMDVVRNAVEKVNGSLALHS 685 +GL++ ++LER+S Q+ ++L+F GFST E VSDLSGRGVGMD VR A+E+ G+L L S Sbjct: 550 RGLVEASKLERMSQQEIIHLIFEPGFSTVEQVSDLSGRGVGMDAVRTAIERNGGTLTLSS 609 Query: 686 VSGKGTRLQISLPLSMAVTKVMIIESDGQLFGVPMEHVMETVRVPR-SSLHFANSSAKMV 744 GKG+ + + LPLSM +++VM+ E + Q F +P+E V++T+++ R + + + Sbjct: 610 EPGKGSEITMILPLSMTISRVMMFELEQQSFAIPIESVIQTLKISRHKDIRRVKNLDTFI 669 Query: 745 LRGHILGLKGINQILGIAAEQKTNADGEVAVLVVRVGGQSVGLVIDDFRETVDVIQKPLL 804 LRG + + + + + + Q D + +LVVRVG +GL +D +E DVI KPL Sbjct: 670 LRGETVPILYLKRAFEMNSAQ-IYPDIQ-PILVVRVGDDVLGLAVDRLQEGQDVIIKPLE 727 Query: 805 GILGGLSLYSGSALMGDGSVLMVLNTREM 833 G L S+Y G+A+MGDG VL+VL+T E+ Sbjct: 728 GALATFSIYRGAAIMGDGRVLLVLDTEEV 756 Score = 100 bits (249), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 75/280 (26%), Positives = 124/280 (44%), Gaps = 24/280 (8%) Query: 1 MTLLRDQFIIETRDLLQGISEKLMQLEDAPEHVELLESLFRMVHTLKGNSGLFD-VPEMT 59 M + FIIE+RDL++ + L+ LE P+ ++ LFR +HT+KG SG+ D + T Sbjct: 1 MNPIMQNFIIESRDLIESAARGLLALEANPDDKAIINELFREIHTVKGASGILDNIAPFT 60 Query: 60 RVLHACEDLMDAVRRRQVAYSEVLADRLLDAMDFVAMLCDGLEMEAEQADPHAQEAVQIA 119 ++ H EDLM VR VA + + D +L CD + E+ + H + + + Sbjct: 61 QLAHRMEDLMQKVRDGHVALNGTMLDLMLGC-------CDQFLLWIEELEQHQELSAEAV 113 Query: 120 SSLRQLIGEHAGVESAVGDLARIGDAQDRGAAIVAAPAAGQALPLRAIPEPLRRQAFAQA 179 S +Q+I + A + A VAA L + + E L R F Sbjct: 114 SISKQMIAQLAPLTQAA--------PTHTPTPAVAAQEETATLSISELTELLGRDCFNDV 165 Query: 180 QAGGELH----WIAYRPSRECFFQGDDPFHRAREVPGFIWGRIDAPAGWPPLAELNAYDC 235 +A E H + Y P ++CFF GDDP R V W ++ P + Y Sbjct: 166 EALLE-HPDALLLIYTPDKQCFFSGDDPLAWMRSVEKVSWRKV---VLIPDSEPFDTYQA 221 Query: 236 VLHFQIVAAASQAELMEYFRYVPDQVELTQLAAQWLAPAP 275 + F ++ +++ +L + + Q L ++ + L AP Sbjct: 222 QMQFLLLTQSAKKDLEQQLAPIEGQYRLYRIQSDNLPTAP 261 >HP0392_1 [NT] COG0643 Chemotaxis protein histidine kinase and related kinases Hpy Helicobacter pylori 26695 Length = 651 Score = 319 bits (818), Expect = 1e-86, Method: Compositional matrix adjust. Identities = 171/472 (36%), Positives = 290/472 (61%), Gaps = 10/472 (2%) Query: 371 PLQRGPAVPAASVESAQAEAVA---VEMRQESLPQPEALSRQES-PQVQLQPPAPPLRES 426 PL P + A++ + + EA + RQE+ + A +QE+ P+ ++ P + Sbjct: 179 PLADEPDLDYANMSAEEVEAEIERLLNKRQEADKERRAQKKQEAKPKQEVTPTKETPKAP 238 Query: 427 LPEESGRAGRRAEE----SLSGNKSVKVEQVKIDRLMNLIGEMVVSKNALPYLAQRAEDQ 482 E +A EE S+ ++V+V+ ++D LMNLIGE+V+ KN L + E++ Sbjct: 239 KTETKAKAKADTEENKAPSIGVEQTVRVDVRRLDHLMNLIGELVLGKNRLIRIYSDVEER 298 Query: 483 FGVRELAREIKAQYAVINRIAEEMQDAIMQVRMMPVSVVFQRFPRLVRDISRKLGKEVQL 542 + + E+ + I+ + ++Q A+M+ RM PV VF +FPR+VRD+SR+LGK ++L Sbjct: 299 YDGEKFLEELNQVVSSISAVTTDLQLAVMKTRMQPVGKVFNKFPRMVRDLSRELGKSIEL 358 Query: 543 VLVGEETEADKNIIEALADPLIHIVRNSLDHGLEGPEQRRASGKPALGSLTISAAHEGDQ 602 ++ GEETE DK+I+E + DPLIHI+RNS DHG+E E+RR KP G + +SA +EG+ Sbjct: 359 IIEGEETELDKSIVEEIGDPLIHIIRNSCDHGIEPLEERRKLNKPETGKVQLSAYNEGNH 418 Query: 603 VVIVIEDDGKGIDPALIKRKAYEKGLIDEAQLERISDQDAVNLVFSSGFSTAEVVSDLSG 662 +VI I DDGKG+DP ++K KA EKG+I E E +SD++A NL+F GFSTA+VVS++SG Sbjct: 419 IVIKISDDGKGLDPVMLKEKAIEKGVISERDAEGMSDREAFNLIFKPGFSTAKVVSNVSG 478 Query: 663 RGVGMDVVRNAVEKVNGSLALHSVSGKGTRLQISLPLSMAVTKVMIIESDGQLFGVPMEH 722 RGVGMDVV+ +EK+NG + + S G GT ++ +PL++A+ + +++ + + +P+ Sbjct: 479 RGVGMDVVKTNIEKLNGIIEIDSEVGVGTTQKLKIPLTLAIIQALLVGVQEEYYAIPLSS 538 Query: 723 VMETVRVPRSSLHFANSSAKMVLRGHILGLKGINQILGIAAEQKTNADGEVAVLVVRVGG 782 V+ETVR+ + ++ + + + LR +L L ++ I + A ++N+D V V+++ + Sbjct: 539 VLETVRISQDEIYTVDGKSVLRLRDEVLSLVRLSDIFKVDAILESNSD--VYVVIIGLAD 596 Query: 783 QSVGLVIDDFRETVDVIQKPLLGILGGLSLYSGSALMGDGSVLMVLNTREMF 834 Q +G+++D +V+ K L L +G+ + GDG + ++++ M Sbjct: 597 QKIGVIVDYLIGQEEVVIKSLGYYLKNTRGIAGATVRGDGKITLIVDVGAMM 648 >jhp0989_1 [NT] COG0643 Chemotaxis protein histidine kinase and related kinases jHp Helicobacter pylori J99 Length = 663 Score = 310 bits (795), Expect = 8e-84, Method: Compositional matrix adjust. Identities = 171/485 (35%), Positives = 290/485 (59%), Gaps = 24/485 (4%) Query: 371 PLQRGPAVPAASVESAQAEAVA---VEMRQESLPQPEALSRQESPQVQLQPPAPPLRESL 427 PL P + A++ + + EA + RQE+ + A +QE Q + + P +E+ Sbjct: 179 PLADEPDLDYANMSAEEVEAEIERLLNKRQEADKERRAQKKQED-QAKPKQEVAPAKETP 237 Query: 428 PEESGRAGRR--------------AEE----SLSGNKSVKVEQVKIDRLMNLIGEMVVSK 469 E+ + R EE S+ ++V+V+ ++D LMNLIGE+V+ K Sbjct: 238 KTETPKTETRKVPKAETKAKAKADTEENKAPSIGVEQTVRVDVRRLDHLMNLIGELVLGK 297 Query: 470 NALPYLAQRAEDQFGVRELAREIKAQYAVINRIAEEMQDAIMQVRMMPVSVVFQRFPRLV 529 N L + E+++ + E+ + I+ + ++Q A+M+ RM PV VF +FPR+V Sbjct: 298 NRLIRIYSDVEERYDGEKFLEELNQVVSSISAVTTDLQLAVMKTRMQPVGKVFNKFPRMV 357 Query: 530 RDISRKLGKEVQLVLVGEETEADKNIIEALADPLIHIVRNSLDHGLEGPEQRRASGKPAL 589 RD+SR+LGK ++L++ GEETE DK+I+E + DPLIHI+RNS DHG+E E+RR KP Sbjct: 358 RDLSRELGKSIELIIEGEETELDKSIVEEIGDPLIHIIRNSCDHGIEPLEERRRLNKPET 417 Query: 590 GSLTISAAHEGDQVVIVIEDDGKGIDPALIKRKAYEKGLIDEAQLERISDQDAVNLVFSS 649 G + +SA +EG+ +VI I DDGKG+DP ++K KA EKG+I E E +SD++A NL+F Sbjct: 418 GKVQLSAYNEGNHIVIKISDDGKGLDPVMLKEKAIEKGVISERDAESMSDREAFNLIFKP 477 Query: 650 GFSTAEVVSDLSGRGVGMDVVRNAVEKVNGSLALHSVSGKGTRLQISLPLSMAVTKVMII 709 GFST +VVS++SGRGVGMDVV+ +EK+NG + + S G GT ++ +PL++A+ + +++ Sbjct: 478 GFSTRKVVSNVSGRGVGMDVVKTNIEKLNGIIEIDSEVGVGTTQKLKIPLTLAIIQALLV 537 Query: 710 ESDGQLFGVPMEHVMETVRVPRSSLHFANSSAKMVLRGHILGLKGINQILGIAAEQKTNA 769 + + +P+ V+ETVR+ + ++ + + + LR +L L ++ I + A ++N+ Sbjct: 538 GVQEEYYAIPLSSVLETVRISQDEIYTVDGKSVLRLRDEVLSLVRLSDIFKVDAILESNS 597 Query: 770 DGEVAVLVVRVGGQSVGLVIDDFRETVDVIQKPLLGILGGLSLYSGSALMGDGSVLMVLN 829 D V V+++ + Q +G+++D +V+ K L L +G+ + GDG + ++++ Sbjct: 598 D--VYVVIIGLADQKIGVIVDYLIGQEEVVIKSLGYYLKNTRGIAGATVRGDGKITLIVD 655 Query: 830 TREMF 834 M Sbjct: 656 VGAMM 660 >TM0702 [NT] COG0643 Chemotaxis protein histidine kinase and related kinases Tma Thermotoga maritima Length = 671 Score = 305 bits (780), Expect = 4e-82, Method: Compositional matrix adjust. Identities = 145/385 (37%), Positives = 261/385 (67%), Gaps = 11/385 (2%) Query: 445 NKSVKVEQVKIDRLMNLIGEMVVSKNALPYLAQRAEDQFGVRELAREIKAQYAVINRIAE 504 +++V+V+ K+D LM+L+GE+V++++ + ++ + ++EL + ++RI Sbjct: 293 SQTVRVDIEKLDNLMDLMGELVIARSRILETLKK----YNIKELDESLSH----LSRITL 344 Query: 505 EMQDAIMQVRMMPVSVVFQRFPRLVRDISRKLGKEVQLVLVGEETEADKNIIEALADPLI 564 ++Q+ +M++RM+P+S VF RFPR+VRD+++K+ KEV ++ GE+TE D+ +E + +PL+ Sbjct: 345 DLQNVVMKIRMVPISFVFNRFPRMVRDLAKKMNKEVNFIMRGEDTELDRTFVEEIGEPLL 404 Query: 565 HIVRNSLDHGLEGPEQRRASGKPALGSLTISAAHEGDQVVIVIEDDGKGIDPALIKRKAY 624 H++RN++DHG+E E+R A GKP +G+L +SA HEG+ VVI +EDDG+GID I RKA Sbjct: 405 HLLRNAIDHGIEPKEERIAKGKPPIGTLILSARHEGNNVVIEVEDDGRGIDKEKIIRKAI 464 Query: 625 EKGLIDEAQLERISDQDAVNLVFSSGFSTAEVVSDLSGRGVGMDVVRNAVEKVNGSLALH 684 EKGLIDE++ +SDQ+ +N +F GFST E VS++SGRGVGMDVV+N VE +NGS+++ Sbjct: 465 EKGLIDESKAATLSDQEILNFLFVPGFSTKEKVSEVSGRGVGMDVVKNVVESLNGSISIE 524 Query: 685 SVSGKGTRLQISLPLSMAVTKVMIIESDGQLFGVPMEHVMETVRVPRSSLHFANSSAKMV 744 S KGT++ I LPL++A+ + ++++ + ++ +P+ ++ + + + + +V Sbjct: 525 SEKDKGTKVTIRLPLTLAIIQALLVKVNNLVYAIPIANIDTILSISKEDIQRVQDRDVIV 584 Query: 745 LRGHILGLKGINQILGIAAEQKTNADGEVAVLVVRVGGQSVGLVIDDFRETVDVIQKPLL 804 +RG ++ + + ++L I +++ V +VRVG + G+V+DD D++ K L Sbjct: 585 IRGEVIPVYRLWEVLQIEHKEELEEMEAV---IVRVGNRKYGIVVDDLLGQDDIVIKSLG 641 Query: 805 GILGGLSLYSGSALMGDGSVLMVLN 829 + + +SG+A++GDGS+ +++N Sbjct: 642 KVFSEVKEFSGAAILGDGSIALIIN 666 Score = 70.9 bits (172), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 35/119 (29%), Positives = 62/119 (52%), Gaps = 5/119 (4%) Query: 8 FIIETRDLLQGISEKLMQLEDAPEHVELLESLFRMVHTLKGNSGLFDVPEMTRVLHACED 67 F+ ET++ LQ +++ L++LE PE +EL+ FR +HTLKG +G M ++ H E+ Sbjct: 9 FVDETKEYLQNLNDTLLELEKNPEDMELINEAFRALHTLKGMAGTMGFSSMAKLCHTLEN 68 Query: 68 LMDAVRRRQVAYSEVLADRLLDAMDFVAMLCDGLEME-----AEQADPHAQEAVQIASS 121 ++D R ++ + L D++ +D + + D + E E D + ASS Sbjct: 69 ILDKARNSEIKITSDLLDKIFAGVDMITRMVDKIVSEGSDDIGENIDVFSDTIKSFASS 127 >PH0484 [NT] COG0643 Chemotaxis protein histidine kinase and related kinases Pho Pyrococcus horikoshii Length = 766 Score = 298 bits (763), Expect = 4e-80, Method: Compositional matrix adjust. Identities = 146/381 (38%), Positives = 248/381 (65%), Gaps = 12/381 (3%) Query: 445 NKSVKVEQVKIDRLMNLIGEMVVSKNALPYLAQRAEDQFGVRELAREIKAQYAVINRIAE 504 ++ +K++ +D+LMNL+GE+V++K L + +R D RE+ + ++R+ Sbjct: 383 SRVIKIDVGHLDKLMNLVGELVITKGRLEQIGERLGD--------RELFEALSTLSRLLT 434 Query: 505 EMQDAIMQVRMMPVSVVFQRFPRLVRDISRKLGKEVQLVLVGEETEADKNIIEALADPLI 564 E+QD IM++R+ P++ VF +FPR+VRD++RK+GKEV+ V+ G + E D+ I+E L D L+ Sbjct: 435 ELQDEIMEMRLTPIAEVFNKFPRMVRDLARKMGKEVEFVMEGADIEVDRTILEKLGDALV 494 Query: 565 HIVRNSLDHGLEGPEQRRASGKPALGSLTISAAHEGDQVVIVIEDDGKGIDPALIKRKAY 624 H++RN++DHG+E PE+R GKP G + + A E + VVI++ DDG+GIDP +KRKA Sbjct: 495 HLLRNAVDHGIEPPEERVKLGKPRAGRVELIAKREKNHVVIIVRDDGRGIDPEKVKRKAV 554 Query: 625 EKGLIDEAQLERISDQDAVNLVFSSGFSTAEVVSDLSGRGVGMDVVRNAVEKVNGSLALH 684 E+GLI + +SD++A+NL+F GFSTA+ V+D+SGRGVGMDVV+ V+ +NGS+++ Sbjct: 555 ERGLITPEEAANLSDEEAINLIFLPGFSTADKVTDVSGRGVGMDVVKEVVKSMNGSISVQ 614 Query: 685 SVSGKGTRLQISLPLSMAVTKVMIIESDGQLFGVPMEHVMETVRVPRSSLHFANSSAKMV 744 + GKGT + LP+SMA+ + ++I + + + +P+ +++ET+ V S L +V Sbjct: 615 TEVGKGTTFILKLPISMAIIQALLIRVEDETYAIPINNILETIEVDPSILKTVGGKPVIV 674 Query: 745 LRGHILGLKGINQILGIAAEQKTNADGEVAVLVVRVGGQSVGLVIDDFRETVDVIQKPLL 804 LRG I+ + ++++ G+ A Q ++V G Q V + +D+ D++ K L Sbjct: 675 LRGEIIPVIMLHELFGLPAPQVDR----FPAIIVDHGAQKVAIGVDELLHKRDIVIKSLG 730 Query: 805 GILGGLSLYSGSALMGDGSVL 825 L + ++G+ ++GDGSV+ Sbjct: 731 KFLSNVRGFAGATILGDGSVV 751 >PAB1332 [NT] COG0643 Chemotaxis protein histidine kinase and related kinases Pab Pyrococcus abyssi Length = 772 Score = 294 bits (753), Expect = 5e-79, Method: Compositional matrix adjust. Identities = 145/381 (38%), Positives = 247/381 (64%), Gaps = 12/381 (3%) Query: 445 NKSVKVEQVKIDRLMNLIGEMVVSKNALPYLAQRAEDQFGVRELAREIKAQYAVINRIAE 504 ++ +K++ +D+LMNL+GE+V++K L + +R D RE+ + ++R+ Sbjct: 389 SRIIKIDVGHLDKLMNLVGELVITKGRLEQIGERLGD--------RELFEALSTLSRLLT 440 Query: 505 EMQDAIMQVRMMPVSVVFQRFPRLVRDISRKLGKEVQLVLVGEETEADKNIIEALADPLI 564 E+QD IM++R+ P++ VF +FPR+VRD++RK+GKEV+ V+ G + E D+ I+E L D L+ Sbjct: 441 ELQDEIMEMRLTPIAEVFNKFPRMVRDLARKMGKEVEFVMEGADIEVDRTILEKLGDALV 500 Query: 565 HIVRNSLDHGLEGPEQRRASGKPALGSLTISAAHEGDQVVIVIEDDGKGIDPALIKRKAY 624 H++RN++DHG+E PE+R GKP +G + + A E + VVI++ DDG+GIDP +K+KA Sbjct: 501 HLLRNAVDHGIEPPEERVKLGKPRVGRVELIAKREKNHVVIIVRDDGRGIDPEKVKKKAI 560 Query: 625 EKGLIDEAQLERISDQDAVNLVFSSGFSTAEVVSDLSGRGVGMDVVRNAVEKVNGSLALH 684 E+GLI + +SD++A+NL+F GFSTAE V+D+SGRGVGMDVV+ V+ +NGS+++ Sbjct: 561 ERGLITPEEAASLSDEEAINLIFLPGFSTAEKVTDVSGRGVGMDVVKEVVKSMNGSISVQ 620 Query: 685 SVSGKGTRLQISLPLSMAVTKVMIIESDGQLFGVPMEHVMETVRVPRSSLHFANSSAKMV 744 + GKGT + LP+SMA+ + ++I + + +P+ +++ET+ V S L +V Sbjct: 621 TEVGKGTTFILKLPISMAIIQALLIRVMDETYAIPINNILETIEVDPSILKTIGGKPVIV 680 Query: 745 LRGHILGLKGINQILGIAAEQKTNADGEVAVLVVRVGGQSVGLVIDDFRETVDVIQKPLL 804 LRG I+ + ++++ G+ Q ++V G Q V + +D+ D++ K L Sbjct: 681 LRGEIIPVVMLHELFGLPTPQVER----FPAIIVDHGAQKVAIGVDELLHKRDIVIKSLG 736 Query: 805 GILGGLSLYSGSALMGDGSVL 825 L + ++G+ ++GDGSV+ Sbjct: 737 KFLSNVRGFAGATILGDGSVV 757 >Cj0284c_1 [NT] COG0643 Chemotaxis protein histidine kinase and related kinases Cje Campylobacter jejuni Length = 622 Score = 294 bits (753), Expect = 5e-79, Method: Compositional matrix adjust. Identities = 176/537 (32%), Positives = 298/537 (55%), Gaps = 46/537 (8%) Query: 328 TLMNCCRSIGNLELIGELEIARQQSLQLRSCDPLLAWLNANPLPLQRGPAVPAASVESAQ 387 TL+N R GN IG +P+ A L A + P V S E + Sbjct: 99 TLLNSIRDNGNDTAIG------------MDIEPICARLTA--ISEGESPVVATDSNEKSI 144 Query: 388 AEAVAVEMRQE-SLPQPEA----LS----------------------RQESPQVQLQPPA 420 +A +QE + P+PE LS R + Q P Sbjct: 145 PQAELEAPKQEIATPEPEVDVNQLSDSEVEAEIERLLKVRKAEDQARRAQKKQTTNAAPK 204 Query: 421 PPLRE-SLPEESGRAGRRAEES--LSGNKSVKVEQVKIDRLMNLIGEMVVSKNALPYLAQ 477 P + P ESG A S S +++++VE ++D LMNLIGE+V+ KN L + Sbjct: 205 PTNNTANKPTESGEKKVPASGSNASSMDQTIRVEVKRLDHLMNLIGELVLGKNRLLKIYD 264 Query: 478 RAEDQFGVRELAREIKAQYAVINRIAEEMQDAIMQVRMMPVSVVFQRFPRLVRDISRKLG 537 E+++ + E+ + ++ I ++Q A+M+ RM P++ VF +FPR+VRD+SR+LG Sbjct: 265 DVEERYEGEKFLEELNQVVSQLSIIITDVQLAVMKTRMQPIAKVFNKFPRVVRDLSRELG 324 Query: 538 KEVQLVLVGEETEADKNIIEALADPLIHIVRNSLDHGLEGPEQRRASGKPALGSLTISAA 597 K+++L + GEETE DK+I+E + DP++H++RNS DHG+E P R A+GKP G + + A Sbjct: 325 KQIELEITGEETELDKSIVEEIGDPIMHMIRNSCDHGVEDPATRAANGKPEKGIVQLKAY 384 Query: 598 HEGDQVVIVIEDDGKGIDPALIKRKAYEKGLIDEAQLERISDQDAVNLVFSSGFSTAEVV 657 +EG+ +V+ I DDGKG+DP +K KA EK LI E + ++++D++A L+F GFSTA V Sbjct: 385 NEGNHIVVEITDDGKGLDPNGLKAKAIEKNLITEREADQMTDKEAFALIFKPGFSTAAKV 444 Query: 658 SDLSGRGVGMDVVRNAVEKVNGSLALHSVSGKGTRLQISLPLSMAVTKVMIIESDGQLFG 717 +++SGRGVGMDVV+ +EK+NG + + S GKG+ ++ +PL++A+ + +++ + + + Sbjct: 445 TNVSGRGVGMDVVKTNIEKLNGVIEIDSELGKGSSFKLKIPLTLAIIQSLLVGTQEEFYA 504 Query: 718 VPMEHVMETVRVPRSSLHFANSSAKMVLRGHILGLKGINQILGIAAEQKTNADGEVAVLV 777 +P+ V+ETVRVP ++ + LR +L L ++ + G+ +Q + + V+V Sbjct: 505 IPLASVLETVRVPIDDIYTIEGKNVLRLRDEVLSLVRLSDVFGV--KQVLESGDQTYVVV 562 Query: 778 VRVGGQSVGLVIDDFRETVDVIQKPLLGILGGLSLYSGSALMGDGSVLMVLNTREMF 834 + V +G+++D +++ K + L + +G+ + GDG V ++++ M Sbjct: 563 IGVAESKLGIIVDTLVGQEEIVIKSMGDYLQNIQGIAGATIRGDGRVTLIIDVGAMM 619 Score = 64.3 bits (155), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 29/101 (28%), Positives = 61/101 (60%) Query: 1 MTLLRDQFIIETRDLLQGISEKLMQLEDAPEHVELLESLFRMVHTLKGNSGLFDVPEMTR 60 M + + F++E +L++ I L++LE PE +ELL +FR+ HT+KG+S + +T+ Sbjct: 4 MQEILEDFLVEAFELVEQIDHDLVELESNPEDLELLNRIFRVAHTVKGSSSFLNFDVLTK 63 Query: 61 VLHACEDLMDAVRRRQVAYSEVLADRLLDAMDFVAMLCDGL 101 + H ED+++ R ++ + + D +L+++D + L + + Sbjct: 64 LTHHMEDVLNKARHGELKITPDIMDVVLESIDRMKTLLNSI 104 >PA1458 [NT] COG0643 Chemotaxis protein histidine kinase and related kinases Pae Pseudomonas aeruginosa Length = 753 Score = 290 bits (741), Expect = 1e-77, Method: Compositional matrix adjust. Identities = 144/388 (37%), Positives = 246/388 (63%), Gaps = 10/388 (2%) Query: 447 SVKVEQVKIDRLMNLIGEMVVSKNALPYLAQRAEDQFGVRELAREIKAQYAVINRIAEEM 506 +V+V+ ++D +MN++GE+V+ +N L L + D+ + +A ++ + ++ Sbjct: 369 TVRVDTARLDEIMNMVGELVLVRNRLVRLGLNSGDEAMAKAVAN--------LDVVTGDL 420 Query: 507 QDAIMQVRMMPVSVVFQRFPRLVRDISRKLGKEVQLVLVGEETEADKNIIEALADPLIHI 566 Q ++M+ RM P+ VF RFPRLVRD++R + KE+ L LVGEET+ DKN++EALADPL+H+ Sbjct: 421 QMSVMKTRMQPIKKVFGRFPRLVRDLARNMKKEINLELVGEETDLDKNLVEALADPLVHL 480 Query: 567 VRNSLDHGLEGPEQRRASGKPALGSLTISAAHEGDQVVIVIEDDGKGIDPALIKRKAYEK 626 VRN++DHG+E PE+R A+GKP +G + +SA EGD ++++I DDGKG+D +++ KA EK Sbjct: 481 VRNAVDHGIESPEEREAAGKPRVGQVVLSAEQEGDHILLMITDDGKGMDAEVLRNKAVEK 540 Query: 627 GLIDEAQLERISDQDAVNLVFSSGFSTAEVVSDLSGRGVGMDVVRNAVEKVNGSLALHSV 686 GL++ +R++D + NL+F+ GFST +SD+SGRGVGMDVV+ + ++NG++ + S Sbjct: 541 GLLERDAADRLTDLECYNLIFAPGFSTKTEISDVSGRGVGMDVVKTKISQLNGTVNVFSQ 600 Query: 687 SGKGTRLQISLPLSMAVTKVMIIESDGQLFGVPMEHVMETVRVPRSSLHFANSSAKMVLR 746 G G+++ I +PL++A+ +++ Q F P+ +V E + S + + +++R Sbjct: 601 KGSGSKIVIKVPLTLAIMPTLMVMLGSQAFAFPLVNVNEIFHLDLSRTNVVDGQEVVIVR 660 Query: 747 GHILGLKGINQILGIAAEQKTNADGEVAVLVVRVGGQSVGLVIDDFRETVDVIQKPLLGI 806 L L + + L +A + +G V +L VG Q +G V+D +V+ KPL + Sbjct: 661 DKALPLFYLKRWLVPSAAHEEQGEGHVVIL--SVGTQRIGFVVDQLVGQEEVVIKPLGKM 718 Query: 807 LGGLSLYSGSALMGDGSVLMVLNTREMF 834 L G +G+ + GDG + ++L+ M Sbjct: 719 LQGTPGMAGATITGDGRIALILDVPSML 746 Score = 65.5 bits (158), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 35/108 (32%), Positives = 66/108 (61%), Gaps = 4/108 (3%) Query: 3 LLRDQFIIETRDLLQGISEKLMQLEDAPEHVELLESLFRMVHTLKGNSGLFDVPEMTRVL 62 +L+D F++E ++L+ +SE+L++LE P+ ++LL ++FR HT+KG +G + + Sbjct: 9 ILQD-FLVEAGEILEQLSEQLVELESRPDDMDLLNAIFRGFHTVKGGAGFLQLNALVECC 67 Query: 63 HACEDLMDAVRRRQVAYSEVLADRLLDAMDFVAMLCDGLEMEAEQADP 110 H E++ D +R+ + S L D +L A+D V + D + EQ++P Sbjct: 68 HIAENVFDILRKGERRVSSELMDVVLQALDTVNAMFDQVR---EQSEP 112 >CC0594 [NT] COG0643 Chemotaxis protein histidine kinase and related kinases Ccr Caulobacter vibrioides Length = 764 Score = 283 bits (723), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 156/422 (36%), Positives = 261/422 (61%), Gaps = 16/422 (3%) Query: 411 SPQVQLQPPAPPLRESLPEESGRAGRRAEESLSGNKSVKVEQVKIDRLMNLIGEMVVSKN 470 +P V+ A P P+++ A G ++++V ++ +M L+ E+V+++N Sbjct: 178 APPVETPSAASPAATFEPDQTDSAPEALVSESLGPQTIRVGVDVLEDMMTLVSELVLTRN 237 Query: 471 ALPYLAQRAEDQFGVRELAREIKAQYAVINRIAEEMQDAIMQVRMMPVSVVFQRFPRLVR 530 L L + D+ L R ++ I E+QD++M+ RM P+ +++ PRLVR Sbjct: 238 QLLQLNRGRGDETFTPPLQR--------LSSITGELQDSVMKTRMQPIGQAWKKLPRLVR 289 Query: 531 DISRKLGKEVQLVLVGEETEADKNIIEALADPLIHIVRNSLDHGLEGPEQRRASGKPALG 590 D+S +LGK ++LV+ GE TE D+ ++E + DPL H+VRNS DHGLEGPE RRA+GKP G Sbjct: 290 DLSGELGKPIELVMEGEATELDRQVLEQIRDPLTHMVRNSADHGLEGPEARRAAGKPEAG 349 Query: 591 SLTISAAHEGDQVVIVIEDDGKGIDPALIKRKAYEKGLIDEAQLERISDQDAVNLVFSSG 650 + +SA HEG +VI + DDG+G+D A I+ KA EKG++ A+ E +++ L+F+ G Sbjct: 350 LIHLSAYHEGGAIVIRLRDDGRGLDTARIREKAIEKGIVGRAEAETMTEAQVHRLIFAPG 409 Query: 651 FSTAEVVSDLSGRGVGMDVVRNAVEKVNGSLALHSVSGKGTRLQISLPLSMAVTKVMIIE 710 FSTA VV+++SGRGVGMDVVR+ +E++ G + L S G+G + + +PL++A+ +II Sbjct: 410 FSTAAVVTNVSGRGVGMDVVRSNIEQIGGQIELQSTLGQGCVVTVKIPLTLAIVSALIIR 469 Query: 711 SDGQLFGVPMEHVMETVRVPRSSLHFAN--SSAKMV-LRGHILGLKGINQILGIAAEQKT 767 + G+ F VP V E V+V S H +M+ LR ++ L +++ LG E++ Sbjct: 470 AAGERFAVPQASVQELVKVSADSDHRFEEIEHVRMLRLREQLIPLIDLSEELG--RERRH 527 Query: 768 NADGEVAVLVVRVGGQSVGLVIDDFRETVDVIQKPLLGILGGLSLYSGSALMGDGSVLMV 827 A VL++RVG G+++++ +T +++ KPL +L + ++SG+ L+GDGSV+++ Sbjct: 528 EAK---FVLIMRVGAHRFGVLVEEVIDTEEIVVKPLASVLRTIPVFSGATLLGDGSVVLI 584 Query: 828 LN 829 ++ Sbjct: 585 ID 586 >VC2063 [NT] COG0643 Chemotaxis protein histidine kinase and related kinases Vch Vibrio cholerae Length = 785 Score = 280 bits (717), Expect = 8e-75, Method: Compositional matrix adjust. Identities = 141/388 (36%), Positives = 238/388 (61%), Gaps = 8/388 (2%) Query: 447 SVKVEQVKIDRLMNLIGEMVVSKNALPYLAQRAEDQFGVRELAREIKAQYAVINRIAEEM 506 +V+V+ +D +MN++GE+V+ +N L L + D+ E+ A ++ + ++ Sbjct: 397 TVRVDTSTLDTIMNMVGELVLVRNRLLSLGLNSNDE--------EMSKAVANLDVVTADL 448 Query: 507 QDAIMQVRMMPVSVVFQRFPRLVRDISRKLGKEVQLVLVGEETEADKNIIEALADPLIHI 566 Q A+M+ RM P+ VF RFPR+VRD++R L KE+ L L GEET+ DKN++EALADPLIH+ Sbjct: 449 QGAVMKTRMQPIKKVFGRFPRVVRDLARSLNKEIDLELRGEETDLDKNLVEALADPLIHL 508 Query: 567 VRNSLDHGLEGPEQRRASGKPALGSLTISAAHEGDQVVIVIEDDGKGIDPALIKRKAYEK 626 VRNS+DHG+E P++R +GK G + +SA+ EGD + + I DDG G+DP ++ A ++ Sbjct: 509 VRNSVDHGIEMPDERAKNGKSRTGKVILSASQEGDHIQLAIVDDGAGMDPDKLRGIAVKR 568 Query: 627 GLIDEAQLERISDQDAVNLVFSSGFSTAEVVSDLSGRGVGMDVVRNAVEKVNGSLALHSV 686 G++DE R+++++ NL+F GFS+ E ++D+SGRGVGMDVV+ A+ +NGS+ + S Sbjct: 569 GIMDEDAANRLTNKECFNLIFMPGFSSKEKITDISGRGVGMDVVKTAINTLNGSIDIDST 628 Query: 687 SGKGTRLQISLPLSMAVTKVMIIESDGQLFGVPMEHVMETVRVPRSSLHFANSSAKMVLR 746 GKGT++ I +PL++A+ +++ G F +P+ V E + + + +++R Sbjct: 629 MGKGTKITIKVPLTLAILPTLMVGVAGHPFALPLASVNEIFHLDLRRTNVVDGQLTIIVR 688 Query: 747 GHILGLKGINQILGIAAEQKTNADGEVAVLVVRVGGQSVGLVIDDFRETVDVIQKPLLGI 806 + L + L + G V++V++G Q VGLV+D +V+ KPL + Sbjct: 689 EKSIPLFYLQNWLAPKKGKVQLRQGHGHVVIVQIGSQRVGLVVDTLIGQEEVVIKPLDKL 748 Query: 807 LGGLSLYSGSALMGDGSVLMVLNTREMF 834 L G SG+ + DG + ++L+ ++ Sbjct: 749 LQGTPGMSGATITSDGHIALILDVPDLL 776 Score = 68.2 bits (165), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 34/92 (36%), Positives = 58/92 (63%), Gaps = 1/92 (1%) Query: 3 LLRDQFIIETRDLLQGISEKLMQLEDAPEHVELLESLFRMVHTLKGNSGLFDVPEMTRVL 62 +L+D F++E ++L+ +SE+L++LE+ PE +LL ++FR HT+KG +G + E+ Sbjct: 9 ILQD-FLVEAGEILELLSEQLVELENNPEDRDLLNAIFRGFHTVKGGAGFLALSELVETC 67 Query: 63 HACEDLMDAVRRRQVAYSEVLADRLLDAMDFV 94 H E++ D +R Q S L D +L A+D V Sbjct: 68 HGAENVFDILRNGQRHVSPSLMDTMLKALDTV 99