BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0029.0229.p (280 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value VC1399 [NT] COG1352 Methylase of chemotaxis methyl-accepting pro... 311 1e-84 TP0630 [NT] COG1352 Methylase of chemotaxis methyl-accepting pro... 149 6e-36 RSp1405 [NT] COG1352 Methylase of chemotaxis methyl-accepting pr... 149 8e-36 PA0175 [NT] COG1352 Methylase of chemotaxis methyl-accepting pro... 141 1e-33 CAC0121 [NT] COG1352 Methylase of chemotaxis methyl-accepting pr... 140 4e-33 BB0040 Non COG 138 1e-32 VCA1091 [NT] COG1352 Methylase of chemotaxis methyl-accepting pr... 138 1e-32 ZcheR [NT] COG1352 Methylase of chemotaxis methyl-accepting prot... 137 3e-32 ECs2594 [NT] COG1352 Methylase of chemotaxis methyl-accepting pr... 137 3e-32 cheR [NT] COG1352 Methylase of chemotaxis methyl-accepting prote... 137 3e-32 >VC1399 [NT] COG1352 Methylase of chemotaxis methyl-accepting proteins Vch Vibrio cholerae Length = 288 Score = 311 bits (797), Expect = 1e-84, Method: Compositional matrix adjust. Identities = 151/281 (53%), Positives = 204/281 (72%), Gaps = 2/281 (0%) Query: 1 MNETVISEADFLKFREYFYRKTGISFEATKRYFVDKRLIERIEATGSGSFRHYFSLLRFE 60 MNE VI++ DF +FR+YFY+KTGI FE +KRYFVDKRL++RIE T SFR YF+ LRF+ Sbjct: 1 MNEIVITDTDFCRFRDYFYQKTGIFFENSKRYFVDKRLLQRIELTEHQSFRGYFTYLRFQ 60 Query: 61 ADGKELQLLTNLMTVNETYFLREEYQFQCLVNSMLPEITGNRRSTAPIRIWCIPCSSGEE 120 A G+ELQ + N +TVNETYF RE Q + LV +L +I +R IRIW +PCSSGEE Sbjct: 61 ASGEELQAVINALTVNETYFFREISQLESLVEEVLDDIVRHRPGEL-IRIWSMPCSSGEE 119 Query: 121 AYTLAMYLMERWPGIDQWDVEIISSDIDTGVLRKAQLGRYSARSVQHVPADWMSKYF-LR 179 Y++ ++L+E WP ++Q D+EII+SDIDTG+L+KA G +SARSV+++P ++KYF LR Sbjct: 120 PYSIVLFLLEHWPKLEQVDIEIIASDIDTGILQKAAQGIFSARSVKNLPNSSLNKYFSLR 179 Query: 180 QGDEYQICDALRGAVEFTRVNLAKSEDTKAYRNFDVIFCRNLLIYFDDVSRKEAAETFYE 239 YQ+ D +R +V FT+ NL + + DVIFCRNLLIYFDD+SR+ A E+FYE Sbjct: 180 ADGSYQLIDDIRQSVRFTQTNLNNRAEVQKLGAMDVIFCRNLLIYFDDISRRNAVESFYE 239 Query: 240 ALNLNGFICLGHSESMSRISSLYRVRKFPEAIVYQKTAEAQ 280 LN G + LGHSESMSRISS++ V++F ++ Y K + + Sbjct: 240 QLNPGGVLFLGHSESMSRISSIFHVKRFRKSTGYYKPHKGK 280 >TP0630 [NT] COG1352 Methylase of chemotaxis methyl-accepting proteins Tpa Treponema pallidum Length = 303 Score = 149 bits (377), Expect = 6e-36, Method: Compositional matrix adjust. Identities = 89/278 (32%), Positives = 144/278 (51%), Gaps = 9/278 (3%) Query: 4 TVISEADFLKFREYFYRKTGISFEATKRYFVDKRLIERIEATGSGSFRHYFSLLRFEADG 63 + +S+A+F F+ Y +GI+F A R ++ R+ R+ S Y+ + A Sbjct: 25 STLSDAEFAAFKTLIYEHSGITFSALNRSVLESRIRSRLRELALPSACAYYQ--QVLASS 82 Query: 64 KELQLLTNLMTVNETYFLREEYQFQCLVNSMLPEITGNRRSTA--PIRIWCIPCSSGEEA 121 EL L + +T N T F R + F + ++PE+ +RS I +W CS+GEE Sbjct: 83 AELSALLDSVTTNLTRFFRNKAHFDSFSHYVIPELVKAKRSVGEHSITVWSAGCSTGEEP 142 Query: 122 YTLAMYLMERWPGIDQWDVEIISSDIDTGVLRKAQLGRYSARSVQHVPADWMSKYFLRQG 181 YT+AM L P + ++I+SD+ L A+ G Y V VP +++ YF Sbjct: 143 YTIAMLLKRYAPA--AFSCQVIASDLSLKSLLVARQGYYPRARVSGVPDEYLRAYFRETQ 200 Query: 182 DEYQICDALRGAVEFTRVNLAKSEDTKAYRNFDVIFCRNLLIYFDDVSRKEAAETFYEAL 241 + YQI +R V F NL + +RN DV+FCRN+LIYFD+ ++K E F++A+ Sbjct: 201 EGYQINADIRKMVRFDYHNL---KHRSMHRNVDVLFCRNVLIYFDETAQKAVIERFWDAM 257 Query: 242 NLNGFICLGHSESMSRISSLYRVRKFPEAIVYQKTAEA 279 + + F+ +GHSES+ +++ + K P + QK E Sbjct: 258 SAHSFLFIGHSESLFGMNTKFSFLKTPWGCLCQKNDEG 295 >RSp1405 [NT] COG1352 Methylase of chemotaxis methyl-accepting proteins Rso Ralstonia solanacearum Length = 292 Score = 149 bits (375), Expect = 8e-36, Method: Compositional matrix adjust. Identities = 86/260 (33%), Positives = 133/260 (51%), Gaps = 12/260 (4%) Query: 10 DFLKFREYFYRKTGISFEATKRYFVDKRLIERIEATGSGSFRHYFSLLRFEADGKELQLL 69 DF + R YR+ GIS K V RL R+ SFR Y L E + Sbjct: 23 DFARIRSLIYRRVGISLSDRKSEMVYSRLARRLRIVNIASFRDYLDALENGHLPDEWEAF 82 Query: 70 TNLMTVNETYFLREEYQFQCLVNSMLPEITGNRRSTAPIRIWCIPCSSGEEAYTLAMYLM 129 TN +T N T F RE++ F +L E +R+ P +WC S+GEE Y++A+ L Sbjct: 83 TNALTTNLTAFFREQHHF-----PILAEHAKAKRT--PFSVWCSASSTGEEPYSIAITLA 135 Query: 130 ERWPGIDQWDVEIISSDIDTGVLRKAQLGRYSARSVQHVPADWMSKYFLR----QGDEYQ 185 E + + V +++SD+DT L +A+ G Y V + AD + KYFLR Q + Sbjct: 136 ETFGSMSPGQVSVVASDVDTNALARARAGIYPMERVSALSADRLKKYFLRGTGKQEGYAR 195 Query: 186 ICDALRGAVEFTRVNLAKSEDTKAYRNFDVIFCRNLLIYFDDVSRKEAAETFYEALNLNG 245 + L+ ++F ++NL D + FDVIFCRN++IYFD ++ + E F + + +G Sbjct: 196 VRPELQAMIDFRQINLL-DRDWPLTQKFDVIFCRNVMIYFDKPTQAKILEHFVDVMKPDG 254 Query: 246 FICLGHSESMSRISSLYRVR 265 + GHSES +++ + +R Sbjct: 255 LLFAGHSESFLQVTKAWSLR 274 >PA0175 [NT] COG1352 Methylase of chemotaxis methyl-accepting proteins Pae Pseudomonas aeruginosa Length = 280 Score = 141 bits (356), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 93/258 (36%), Positives = 133/258 (51%), Gaps = 12/258 (4%) Query: 10 DFLKFREYFYRKTGISFEATKRYFVDKRLIERIEATGSGSFRHYFSLLRFEADGKELQLL 69 DF + RE YR TGIS +K V RL R+ GSF YF+ L + + E QL Sbjct: 21 DFQQVRERLYRLTGISLAESKAQLVYSRLSRRLRLLRLGSFAEYFTHL--DREPGEQQLF 78 Query: 70 TNLMTVNETYFLREEYQFQCLVNSMLPEITGNRRSTAPIRIWCIPCSSGEEAYTLAMYLM 129 N +T N T F RE + F L + ++ +R P+RIW S+GEE Y++A+ L+ Sbjct: 79 VNALTTNLTAFFRERHHFPLLADLARRQLQRHR----PLRIWSAAASTGEEPYSIAITLV 134 Query: 130 ERWPGIDQWDVEIISSDIDTGVLRKAQLGRYSARSVQHVPADWMSKYFLR----QGDEYQ 185 E D V+I++SDIDTGVL A+ G Y ++ +PA ++FLR + + Sbjct: 135 EALGSFDP-PVKIVASDIDTGVLDCARQGVYPLERLEQMPAPLKKRFFLRGTGPNAGKAR 193 Query: 186 ICDALRGAVEFTRVNLAKSEDTKAYRNFDVIFCRNLLIYFDDVSRKEAAETFYEALNLNG 245 + + LR VEF ++NL ++ D D IFCRN++IYFD ++ E L G Sbjct: 194 VVEELRQLVEFRQINLLEA-DWSIAGELDAIFCRNVMIYFDKPTQTRLLERMVALLRPEG 252 Query: 246 FICLGHSESMSRISSLYR 263 GHSE+ S L R Sbjct: 253 LFFAGHSENFVHASHLVR 270 >CAC0121 [NT] COG1352 Methylase of chemotaxis methyl-accepting proteins Cac Clostridium acetobutylicum Length = 270 Score = 140 bits (352), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 75/254 (29%), Positives = 140/254 (55%), Gaps = 4/254 (1%) Query: 5 VISEADFLKFREYFYRKTGISFEATKRYFVDKRLIERIEATGSGSFRHYFSLLRFEADGK 64 +++E F + +Y R GI+ +++ R+ + + + + SF + + + G+ Sbjct: 3 ILNETQFKEISDYIRRNFGINLKSSDRHIFANKFDKFLNIIKANSFEEGYHRILNDRTGE 62 Query: 65 ELQLLTNLMTVNETYFLREEYQFQCLVNSMLPEITGNRRSTAPIRIWCIPCSSGEEAYTL 124 +++ +++T+N T+F+RE F + +LP + + +RIWC CSSGEEAYT+ Sbjct: 63 CVRIFLDIITINHTFFMREPEHFYYFRDEVLPYLKSTIKDN-DLRIWCAACSSGEEAYTI 121 Query: 125 AMYLMERWPGIDQ-WDVEIISSDIDTGVLRKAQLGRYSARSVQHVPADWMSKYFLR-QGD 182 AM L E + D W+ +++++DI VL KA G YSA+ +Q V +W YF + + Sbjct: 122 AMILDEFFMRDDSLWERQVLATDISCKVLNKAVRGVYSAKEIQDVMINWKINYFKKIDSN 181 Query: 183 EYQICDALRGAVEFTRVNLAKSEDTKAYRNFDVIFCRNLLIYFDDVSRKEAAETFYEALN 242 +++ ++ + + R NL + E + F VIFCRN+++YFD ++K + FY+ Sbjct: 182 NFEVRKEIKDNIIYRRFNLME-EVFPFKKKFHVIFCRNVMMYFDKYTKKRLIKKFYDNTE 240 Query: 243 LNGFICLGHSESMS 256 G++ +GHSE + Sbjct: 241 KGGYLFIGHSEGID 254 >BB0040 Non COG Length = 283 Score = 138 bits (347), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 80/241 (33%), Positives = 127/241 (52%), Gaps = 5/241 (2%) Query: 19 YRKTGISFEATKRYFVDKRLIERIEATGSGSFRHYFSLLRFEADGKELQLLTNLMTVNET 78 Y GI+ K+ ++ RL ++ G +F Y + L +L L + ++ N T Sbjct: 27 YNNFGINLSEKKKLLIESRLSSLLKVKGFKNFTEYINFLEKSTGNIQLIELIDKISTNHT 86 Query: 79 YFLREEYQFQCLVNSMLPEITGN--RRSTAPIRIWCIPCSSGEEAYTLAMYLMERWP-GI 135 YF RE F L N +LP++T + IRIW CSSGEE YT+AM L E Sbjct: 87 YFFRESKHFDFLNNKILPKLTEKILNSENSEIRIWSAGCSSGEEPYTIAMMLKEYMEHNR 146 Query: 136 DQWDVEIISSDIDTGVLRKAQLGRYSARSVQHVPADWMSKYFLR-QGDEYQICDALRGAV 194 + V+I+++DI VL +A+ G Y + ++P KY + Q D++Q+ + L+ V Sbjct: 147 VNFKVKILATDISISVLNEAREGIYPEDRIINLPKYLKIKYLNQLQDDKFQVKEILKKMV 206 Query: 195 EFTRVNLAKSEDTKAYRNFDVIFCRNLLIYFDDVSRKEAAETFYEALNLNGFICLGHSES 254 F ++NL E + FD+IFCRN++IYFD+ +R A F L + ++ +GHSE+ Sbjct: 207 YFKKLNLM-DEKFPFSKKFDLIFCRNVMIYFDEKTRNNLANKFNSYLKKDSYLLIGHSET 265 Query: 255 M 255 + Sbjct: 266 I 266 >VCA1091 [NT] COG1352 Methylase of chemotaxis methyl-accepting proteins Vch Vibrio cholerae Length = 276 Score = 138 bits (347), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 89/264 (33%), Positives = 144/264 (54%), Gaps = 16/264 (6%) Query: 6 ISEADFLKFREYFYRKT-GISFEATKRYFVDKRLIERIEATGSGSFRHYFSLLRFEADGK 64 +++ DF KF ++F KT GI +KR V RL ++ G F + L+ E+D + Sbjct: 11 LTDKDF-KFIQWFMHKTVGIYLPDSKRTMVYGRLSRQMRRKGLRRFTQFRELI--ESDEQ 67 Query: 65 ELQLLTNLMTVNETYFLREEYQFQCLVNSMLPEITGNRRSTAPIRIWCIPCSSGEEAYTL 124 E N +T N+T F RE + F+ + ++PE + R +R W CS+GEE YTL Sbjct: 68 ERIHFINTLTTNKTEFFRESHHFEFIEKVLVPEWSKER--VGQLRFWSAGCSTGEEPYTL 125 Query: 125 AMYLMERWPGIDQW--DVEIISSDIDTGVLRKAQLGRYSARSVQHVPADWMSKYFLR--- 179 L G+ + D++I ++D+DT VL KA LG Y S +P ++ + F+R Sbjct: 126 VSVLDH--AGVMNFCPDIKIWATDLDTAVLEKASLGIYPIESQSSIPERYLRRCFVRGVK 183 Query: 180 -QGDEYQICDALRGAVEFTRVNLAKSEDTKAYRNFDVIFCRNLLIYFDDVSRKEAAETFY 238 Q +I +L+ ++F ++NL + K + D+I CRN++IYFD ++++ E F+ Sbjct: 184 DQQGNMKIKQSLQRYIDFHQLNLIQEWPFK--QKLDLILCRNVMIYFDRPTQEQLIERFH 241 Query: 239 EALNLNGFICLGHSESMSRISSLY 262 + L G + LGHSES+ R SSL+ Sbjct: 242 QQLKPGGVLMLGHSESVGRCSSLF 265 >ZcheR [NT] COG1352 Methylase of chemotaxis methyl-accepting proteins EcZ Escherichia coli O157:H7 EDL933 Length = 286 Score = 137 bits (345), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 85/268 (31%), Positives = 133/268 (49%), Gaps = 19/268 (7%) Query: 5 VISEADFLKFREYFYRKTGISFEATKRYFVDKRLIERIEATGSGSFRHYFSLLRFEADGK 64 +S+A F + + Y++ GI KR V RL+ R+ + G F HY +LL Sbjct: 21 ALSDAHFRRISQLIYQRAGIVLADHKRDMVYNRLVRRLRSLGLTDFGHYLNLLESNQHSG 80 Query: 65 ELQLLTNLMTVNETYFLREEYQFQCLVNSMLPEITGNRRSTAPIRIWCIPCSSGEEAYTL 124 E Q N +T N T F RE + F L + RR + R+W S+GEE Y++ Sbjct: 81 EWQAFINSLTTNLTAFFREAHHFPLLADHA-------RRRSGEYRVWSAAASTGEEPYSI 133 Query: 125 AMYLMERW---PGIDQWDVEIISSDIDTGVLRKAQLGRYSARSVQHVPADWMSKYFLRQG 181 AM L + PG +W ++ +SDIDT VL KA+ G Y ++++ + +YF+R Sbjct: 134 AMTLADTLGTAPG--RW--KVFASDIDTEVLEKARSGIYRHEELKNLTPQQLQRYFMRGT 189 Query: 182 DEYQ----ICDALRGAVEFTRVNLAKSEDTKAYRNFDVIFCRNLLIYFDDVSRKEAAETF 237 ++ + L V+F +NL + T FD IFCRN++IYFD +++E F Sbjct: 190 GPHEGLVRVRQELANYVDFASLNLLAKQYTVP-GPFDAIFCRNVMIYFDQTTQQEILRRF 248 Query: 238 YEALNLNGFICLGHSESMSRISSLYRVR 265 L +G + GHSE+ S + + +R Sbjct: 249 VPLLKPDGLLFAGHSENFSHLERRFTLR 276 >ECs2594 [NT] COG1352 Methylase of chemotaxis methyl-accepting proteins Ecs Escherichia coli O157:H7 Length = 286 Score = 137 bits (345), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 85/268 (31%), Positives = 133/268 (49%), Gaps = 19/268 (7%) Query: 5 VISEADFLKFREYFYRKTGISFEATKRYFVDKRLIERIEATGSGSFRHYFSLLRFEADGK 64 +S+A F + + Y++ GI KR V RL+ R+ + G F HY +LL Sbjct: 21 ALSDAHFRRISQLIYQRAGIVLADHKRDMVYNRLVRRLRSLGLTDFGHYLNLLESNQHSG 80 Query: 65 ELQLLTNLMTVNETYFLREEYQFQCLVNSMLPEITGNRRSTAPIRIWCIPCSSGEEAYTL 124 E Q N +T N T F RE + F L + RR + R+W S+GEE Y++ Sbjct: 81 EWQAFINSLTTNLTAFFREAHHFPLLADHA-------RRRSGEYRVWSAAASTGEEPYSI 133 Query: 125 AMYLMERW---PGIDQWDVEIISSDIDTGVLRKAQLGRYSARSVQHVPADWMSKYFLRQG 181 AM L + PG +W ++ +SDIDT VL KA+ G Y ++++ + +YF+R Sbjct: 134 AMTLADTLGTAPG--RW--KVFASDIDTEVLEKARSGIYRHEELKNLTPQQLQRYFMRGT 189 Query: 182 DEYQ----ICDALRGAVEFTRVNLAKSEDTKAYRNFDVIFCRNLLIYFDDVSRKEAAETF 237 ++ + L V+F +NL + T FD IFCRN++IYFD +++E F Sbjct: 190 GPHEGLVRVRQELANYVDFASLNLLAKQYTVP-GPFDAIFCRNVMIYFDQTTQQEILRRF 248 Query: 238 YEALNLNGFICLGHSESMSRISSLYRVR 265 L +G + GHSE+ S + + +R Sbjct: 249 VPLLKPDGLLFAGHSENFSHLERRFTLR 276 >cheR [NT] COG1352 Methylase of chemotaxis methyl-accepting proteins Eco Escherichia coli K12 Length = 286 Score = 137 bits (345), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 85/268 (31%), Positives = 133/268 (49%), Gaps = 19/268 (7%) Query: 5 VISEADFLKFREYFYRKTGISFEATKRYFVDKRLIERIEATGSGSFRHYFSLLRFEADGK 64 +S+A F + + Y++ GI KR V RL+ R+ + G F HY +LL Sbjct: 21 ALSDAHFRRISQLIYQRAGIVLADHKRDMVYNRLVRRLRSLGLTDFGHYLNLLESNQHSG 80 Query: 65 ELQLLTNLMTVNETYFLREEYQFQCLVNSMLPEITGNRRSTAPIRIWCIPCSSGEEAYTL 124 E Q N +T N T F RE + F L + RR + R+W S+GEE Y++ Sbjct: 81 EWQAFINSLTTNLTAFFREAHHFPLLADHA-------RRRSGEYRVWSAAASTGEEPYSI 133 Query: 125 AMYLMERW---PGIDQWDVEIISSDIDTGVLRKAQLGRYSARSVQHVPADWMSKYFLRQG 181 AM L + PG +W ++ +SDIDT VL KA+ G Y ++++ + +YF+R Sbjct: 134 AMTLADTLGTAPG--RW--KVFASDIDTEVLEKARSGIYRHEELKNLTPQQLQRYFMRGT 189 Query: 182 DEYQ----ICDALRGAVEFTRVNLAKSEDTKAYRNFDVIFCRNLLIYFDDVSRKEAAETF 237 ++ + L V+F +NL + T FD IFCRN++IYFD +++E F Sbjct: 190 GPHEGLVRVRQELANYVDFAPLNLLAKQYTVP-GPFDAIFCRNVMIYFDQTTQQEILRRF 248 Query: 238 YEALNLNGFICLGHSESMSRISSLYRVR 265 L +G + GHSE+ S + + +R Sbjct: 249 VPLLKPDGLLFAGHSENFSHLERRFTLR 276