BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0029.0203.p (302 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CC2298 [I] COG0657 Esterase/lipase Ccr Caulobacter vibrioides 212 7e-55 DR0821_2 [I] COG0657 Esterase/lipase Dra Deinococcus radiodurans 164 2e-40 mll5717 [I] COG0657 Esterase/lipase Mlo Mesorhizobium loti 89 1e-17 Rv1426c [I] COG0657 Esterase/lipase Mtu Mycobacterium tuberculos... 80 6e-15 Rv2284 [I] COG0657 Esterase/lipase Mtu Mycobacterium tuberculosi... 80 8e-15 MT2342 [I] COG0657 Esterase/lipase MtC Mycobacterium tuberculosi... 80 8e-15 Rv0220 [I] COG0657 Esterase/lipase Mtu Mycobacterium tuberculosi... 77 3e-14 MT0230 [I] COG0657 Esterase/lipase MtC Mycobacterium tuberculosi... 77 3e-14 Rv1399c [I] COG0657 Esterase/lipase Mtu Mycobacterium tuberculos... 66 8e-11 MT1443 [I] COG0657 Esterase/lipase MtC Mycobacterium tuberculosi... 66 8e-11 >CC2298 [I] COG0657 Esterase/lipase Ccr Caulobacter vibrioides Length = 289 Score = 212 bits (540), Expect = 7e-55, Method: Compositional matrix adjust. Identities = 120/269 (44%), Positives = 158/269 (58%), Gaps = 8/269 (2%) Query: 24 CSPLTAINAVTPA-STYLKTDGVAYAGSDNARQQLDIYRPADTASAPPQGRPVVVFFYGG 82 CSPL+ VTP + + G Y +D R +DIY P A P PV VFFYGG Sbjct: 23 CSPLSIFATVTPKDAARREAKGARY--TDGPRGGVDIYAPP-IAHGPA---PVAVFFYGG 76 Query: 83 SWNQGSRKDYAFVGEALASRGVIAVLPDYRLYPEVSYPDFLQDSAQAVAWTLRSLQALGG 142 SW+ G R DY + A+A++G + + PDYRLYPEV YPDFL D A+AV W + + ALGG Sbjct: 77 SWDSGRRGDYGWAARAIAAQGFLTLAPDYRLYPEVRYPDFLDDCAKAVRWAVDNAAALGG 136 Query: 143 DPQRVFVMGHSAGAYNAAMMALDARWLDAAGATPAQLRGWIGLAGPYDFLPIENPDVKPV 202 DP+R+ ++GHSAGAYNAAM+ALD R+L G P +R + GL+GPYDFLP++ + Sbjct: 137 DPERIVLIGHSAGAYNAAMLALDPRYLRGVGVDPGAVRAFAGLSGPYDFLPLKGAITERT 196 Query: 203 FHFPDSPPDSQPVRHVQASAPPALLIASHQDKLVSATRNTGGLAALLRQHGVPVVETYFD 262 F +QPV +A AP A L +D V RNT LAA LR G V E ++ Sbjct: 197 FGGAADLAATQPVSFARADAPAAFLATGDKDTTVY-PRNTRKLAAALRDKGARVEERHYP 255 Query: 263 NTSHASLVGSLARPLRFIAPTLDEVSRFI 291 HA V +L+RP R A L +++ F+ Sbjct: 256 GVDHAGAVLALSRPFRRKATLLTDMTAFL 284 >DR0821_2 [I] COG0657 Esterase/lipase Dra Deinococcus radiodurans Length = 242 Score = 164 bits (416), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 88/242 (36%), Positives = 135/242 (55%), Gaps = 7/242 (2%) Query: 52 NARQQLDIYRPADTASAPPQGRPVVVFFYGGSWNQGSRKDYAFVGEALASRGVIAVLPDY 111 + R +LD+Y P + QG P ++F +GGSW G + +AFVGE+LA G + + +Y Sbjct: 4 DTRNKLDVYAPQNA-----QGAPTILFIHGGSWQGGDKSGHAFVGESLARAGYVVGVMNY 58 Query: 112 RLYPEVSYPDFLQDSAQAVAWTLRSLQALGGDPQRVFVMGHSAGAYNAAMMALDARWLDA 171 RL P+ YP ++QD A A+ W GG+P +FV GHSAG +NA + +ARWL Sbjct: 59 RLAPQNRYPSYVQDGAAALKWLRDHAGQFGGNPNNLFVSGHSAGGFNAVELVDNARWLAE 118 Query: 172 AGATPAQLRGWIGLAGPYDFLPIENPDVKPVFHFPDSPPDSQPVRHVQASAPPALLIASH 231 + +RG IG+AGPY + + F +P D P RHV+ APP LL+ + Sbjct: 119 VNVPVSSIRGVIGIAGPYSY-DFRAYQTRVAFPENGNPDDIMPDRHVRPDAPPHLLLVAA 177 Query: 232 QDKLVSATRNTGGLAALLRQHGVPVVETYFDNTSHASLVGSLARPLRFIAPTLDEVSRFI 291 D +V A +N + A L++ +PV +H +++G++AR L ++ T E+ RF+ Sbjct: 178 NDSVV-APQNALNMEAALQKARIPVQRVVLPRLNHVTIIGAVARNLTWLGGTRAEIIRFV 236 Query: 292 DA 293 DA Sbjct: 237 DA 238 >mll5717 [I] COG0657 Esterase/lipase Mlo Mesorhizobium loti Length = 309 Score = 89.0 bits (219), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 57/168 (33%), Positives = 84/168 (50%), Gaps = 19/168 (11%) Query: 44 GVAYAGSDNARQQLDIYRPADTASAPPQGR---PVVVFFYGGSWNQGSRKDYAFVGEALA 100 VAY + A ++LD++ PP GR PV VF +GG W SR DY++V + Sbjct: 73 NVAYG--NGAAERLDLF-------FPPGGRKNIPVHVFIHGGYWRMFSRGDYSYVANTVT 123 Query: 101 SRGVIAVLPDYRLYPEVSYPDFLQDSAQAVAWTLRSLQALGGDPQRVFVMGHSAGAYNAA 160 G IAV+ DY L PE ++ +A W L ++ GGDP R+ V GHSAGA+ A Sbjct: 124 RAGAIAVIVDYALMPEFRMAAIVEQVRRAKQWVLDNIVDHGGDPGRMSVSGHSAGAHLAT 183 Query: 161 MMALDARWLDAAGATPAQLRGWIGLAGPYDFLPIENPDVKPVFHFPDS 208 +L P+++R + L G YD P++ ++P+ D Sbjct: 184 -------FLFEKTPVPSRIRAALLLGGLYDLKPLQKSFLEPLIGITDE 224 >Rv1426c [I] COG0657 Esterase/lipase Mtu Mycobacterium tuberculosis H37Rv Length = 420 Score = 80.1 bits (196), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 65/216 (30%), Positives = 100/216 (46%), Gaps = 21/216 (9%) Query: 39 YLKTDGVAYAGSDNARQQLDIYRPADTASAPPQGR-PVVVFFYGGSWNQGSRKDYAF-VG 96 Y++T V G DI+R D P + PV+V GG+W G R+ A+ + Sbjct: 146 YVETTNVVCYGPYGRANLADIWRRRDL---PRDAKAPVLVQVPGGAWVLGWRRPQAYPLM 202 Query: 97 EALASRGVIAVLPDYRLYPEVSYPDFLQDSAQAVAWTLRSLQALGGDPQRVFVMGHSAGA 156 LA+RG + V +YR+ P ++PD + D +A+AW ++ A GGDP V + G SAG Sbjct: 203 SHLAARGWVCVSLNYRVSPRHTWPDHIVDVKRALAWVKENIAAYGGDPNFVAISGGSAGG 262 Query: 157 YNAAMMAL---DARWLDAAGATPAQLRGWIGLAGPYDFLPIENPD------------VKP 201 + A+ AL D R+ + + + G YD+ + P VK Sbjct: 263 HLCALAALTPNDPRFQPGFEQVDTSVAAAVPVYGRYDWFTTDAPGRREFVGLLETFVVKR 322 Query: 202 VFH-FPDSPPDSQPVRHVQASAPPALLIASHQDKLV 236 F D D+ P+ HV+A APP ++ D L+ Sbjct: 323 KFSTHRDIFVDASPIHHVRADAPPFFVLHGRHDSLI 358 >Rv2284 [I] COG0657 Esterase/lipase Mtu Mycobacterium tuberculosis H37Rv Length = 431 Score = 79.7 bits (195), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 72/251 (28%), Positives = 111/251 (44%), Gaps = 26/251 (10%) Query: 43 DGVAYAGSDNARQQLDIYRPAD---TASAPPQGRPVVVFFYGGSWNQGSRKDYAF-VGEA 98 DG G LDI+R D T +AP V+ GG+W G+++ A + Sbjct: 152 DGDISYGEYGRANHLDIWRRPDLDLTGTAP-----VLFQIPGGAWTTGNKRGQAHPLMSH 206 Query: 99 LASRGVIAVLPDYRLYPEVSYPDFLQDSAQAVAWTLRSLQALGGDPQRVFVMGHSAGAYN 158 LA G I V +YR P ++PD + D +A+AW + GGDP + + G SAG + Sbjct: 207 LAELGWICVAINYRHSPRNTWPDHIIDVKRALAWVKAHISEYGGDPDFIAITGGSAGGHL 266 Query: 159 AAMMAL---DARWLDAAGATPAQLRGWIGLAGPYDFLPIEN---PDVKPVFHF------- 205 +++ AL D R+ +++ + G YDF +++ P + P+ Sbjct: 267 SSLAALTPNDPRFQPGFEEADTRVQAAVPFYGVYDFTRLQDAMHPMMLPLLERMVVKQPR 326 Query: 206 ---PDSPPDSQPVRHVQASAPPALLIASHQDKLVSATRNTGGLAALLRQHGVPVVETYFD 262 S D+ PV H+ A APP ++ D LV + G + L + PVV Sbjct: 327 TANMQSYLDASPVTHISADAPPFFVLHGRNDSLVPVQQARGFVDQLRQVSKQPVVYAELP 386 Query: 263 NTSHA-SLVGS 272 T HA L+GS Sbjct: 387 FTQHAFDLLGS 397 >MT2342 [I] COG0657 Esterase/lipase MtC Mycobacterium tuberculosis CDC1551 Length = 431 Score = 79.7 bits (195), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 72/251 (28%), Positives = 111/251 (44%), Gaps = 26/251 (10%) Query: 43 DGVAYAGSDNARQQLDIYRPAD---TASAPPQGRPVVVFFYGGSWNQGSRKDYAF-VGEA 98 DG G LDI+R D T +AP V+ GG+W G+++ A + Sbjct: 152 DGDISYGEYGRANHLDIWRRPDLDLTGTAP-----VLFQIPGGAWTTGNKRGQAHPLMSH 206 Query: 99 LASRGVIAVLPDYRLYPEVSYPDFLQDSAQAVAWTLRSLQALGGDPQRVFVMGHSAGAYN 158 LA G I V +YR P ++PD + D +A+AW + GGDP + + G SAG + Sbjct: 207 LAELGWICVAINYRHSPRNTWPDHIIDVKRALAWVKAHISEYGGDPDFIAITGGSAGGHL 266 Query: 159 AAMMAL---DARWLDAAGATPAQLRGWIGLAGPYDFLPIEN---PDVKPVFHF------- 205 +++ AL D R+ +++ + G YDF +++ P + P+ Sbjct: 267 SSLAALTPNDPRFQPGFEEADTRVQAAVPFYGVYDFTRLQDAMHPMMLPLLERMVVKQPR 326 Query: 206 ---PDSPPDSQPVRHVQASAPPALLIASHQDKLVSATRNTGGLAALLRQHGVPVVETYFD 262 S D+ PV H+ A APP ++ D LV + G + L + PVV Sbjct: 327 TANMQSYLDASPVTHISADAPPFFVLHGRNDSLVPVQQARGFVDQLRQVSKQPVVYAELP 386 Query: 263 NTSHA-SLVGS 272 T HA L+GS Sbjct: 387 FTQHAFDLLGS 397 >Rv0220 [I] COG0657 Esterase/lipase Mtu Mycobacterium tuberculosis H37Rv Length = 403 Score = 77.4 bits (189), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 58/205 (28%), Positives = 95/205 (46%), Gaps = 23/205 (11%) Query: 51 DNARQQLDIYRPADTASAPPQGRPVVVFFYGGSWNQGSR--KDYAFVGEALASRGVIAVL 108 D+ Q LD++R D + P PV++F GG+W GSR + YA + LA++G + + Sbjct: 137 DDPAQLLDVWRRKDMPTKPA---PVLIFVPGGAWVHGSRAIQGYAVLSR-LAAQGWVCLS 192 Query: 109 PDYRLYPEVSYPDFLQDSAQAVAWTLRSLQALGGDPQRVFVMGHSAGAYNAAMMALDARW 168 DYR+ P +P + D A+AW ++ GGD + V G SAG + +A+ L A Sbjct: 193 IDYRVAPHHRWPRHILDVKTAIAWARANVDKFGGDRNFIAVAGCSAGGHLSALAGLTAND 252 Query: 169 LDAAGATP----AQLRGWIGLAGPYDFLPIENPDVKPVFHF-------------PDSPPD 211 P + +G+ G YD+ P+ F P+ D Sbjct: 253 PQYQAELPEGSDTSVDAVVGIYGRYDWEDRSTPERARFVDFLERVVVQRTIDRHPEVFRD 312 Query: 212 SQPVRHVQASAPPALLIASHQDKLV 236 + P++ V +APP L+I +D ++ Sbjct: 313 ASPIQRVTRNAPPFLVIHGSRDCVI 337 >MT0230 [I] COG0657 Esterase/lipase MtC Mycobacterium tuberculosis CDC1551 Length = 403 Score = 77.4 bits (189), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 58/205 (28%), Positives = 95/205 (46%), Gaps = 23/205 (11%) Query: 51 DNARQQLDIYRPADTASAPPQGRPVVVFFYGGSWNQGSR--KDYAFVGEALASRGVIAVL 108 D+ Q LD++R D + P PV++F GG+W GSR + YA + LA++G + + Sbjct: 137 DDPAQLLDVWRRKDMPTKPA---PVLIFVPGGAWVHGSRAIQGYAVLSR-LAAQGWVCLS 192 Query: 109 PDYRLYPEVSYPDFLQDSAQAVAWTLRSLQALGGDPQRVFVMGHSAGAYNAAMMALDARW 168 DYR+ P +P + D A+AW ++ GGD + V G SAG + +A+ L A Sbjct: 193 IDYRVAPHHRWPRHILDVKTAIAWARANVDKFGGDRNFIAVAGCSAGGHLSALAGLTAND 252 Query: 169 LDAAGATP----AQLRGWIGLAGPYDFLPIENPDVKPVFHF-------------PDSPPD 211 P + +G+ G YD+ P+ F P+ D Sbjct: 253 PQYQAELPEGSDTSVDAVVGIYGRYDWEDRSTPERARFVDFLERVVVQRTIDRHPEVFRD 312 Query: 212 SQPVRHVQASAPPALLIASHQDKLV 236 + P++ V +APP L+I +D ++ Sbjct: 313 ASPIQRVTRNAPPFLVIHGSRDCVI 337 >Rv1399c [I] COG0657 Esterase/lipase Mtu Mycobacterium tuberculosis H37Rv Length = 319 Score = 66.2 bits (160), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 41/95 (43%), Positives = 52/95 (54%), Gaps = 1/95 (1%) Query: 74 PVVVFFYGGSWNQGSRKDYAFVGEALA-SRGVIAVLPDYRLYPEVSYPDFLQDSAQAVAW 132 PVVV+++GG W+ G + V A A I V DYRL PE YP + DS A+ W Sbjct: 82 PVVVYYHGGGWSLGGLDTHDPVARAHAVGAQAIVVSVDYRLAPEHPYPAGIDDSWAALRW 141 Query: 133 TLRSLQALGGDPQRVFVMGHSAGAYNAAMMALDAR 167 + LGGDP R+ V G SAG +A+MA AR Sbjct: 142 VGENAAELGGDPSRIAVAGDSAGGNISAVMAQLAR 176 >MT1443 [I] COG0657 Esterase/lipase MtC Mycobacterium tuberculosis CDC1551 Length = 319 Score = 66.2 bits (160), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 41/95 (43%), Positives = 52/95 (54%), Gaps = 1/95 (1%) Query: 74 PVVVFFYGGSWNQGSRKDYAFVGEALA-SRGVIAVLPDYRLYPEVSYPDFLQDSAQAVAW 132 PVVV+++GG W+ G + V A A I V DYRL PE YP + DS A+ W Sbjct: 82 PVVVYYHGGGWSLGGLDTHDPVARAHAVGAQAIVVSVDYRLAPEHPYPAGIDDSWAALRW 141 Query: 133 TLRSLQALGGDPQRVFVMGHSAGAYNAAMMALDAR 167 + LGGDP R+ V G SAG +A+MA AR Sbjct: 142 VGENAAELGGDPSRIAVAGDSAGGNISAVMAQLAR 176