BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0029.0116.p (300 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gcvA [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 195 9e-50 ZgcvA [K] COG0583 Transcriptional regulator EcZ Escherichia coli... 195 9e-50 ECs3668 [K] COG0583 Transcriptional regulator Ecs Escherichia co... 195 9e-50 STM2982 [K] COG0583 Transcriptional regulator Sty Salmonella typ... 194 1e-49 VC0896 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae 180 4e-45 YPO1029 [K] COG0583 Transcriptional regulator Ype Yersinia pestis 180 4e-45 PM0567 [K] COG0583 Transcriptional regulator Pmu Pasteurella mul... 169 6e-42 mlr1832 [K] COG0583 Transcriptional regulator Mlo Mesorhizobium ... 153 4e-37 CC1117 Non COG 153 4e-37 mlr1973 [K] COG0583 Transcriptional regulator Mlo Mesorhizobium ... 151 2e-36 >gcvA [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 Length = 305 Score = 195 bits (496), Expect = 9e-50, Method: Compositional matrix adjust. Identities = 114/287 (39%), Positives = 163/287 (56%), Gaps = 11/287 (3%) Query: 7 PLNAIRAFLAAARHQSFTLAAHELNVTHGAISRQIKNLEGYLGMPLFERRTRQVLLTERG 66 PLNA+R F AAARH SFT AA EL VT A+S QIK+LE +LG+ LF RR R +LLTE G Sbjct: 7 PLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSLEDFLGLKLFRRRNRSLLLTEEG 66 Query: 67 RQFFEEASPALEILANAARRVMRDAPTRTVVINVRPSFAVRWLIPHLSDFVERYPGIAPQ 126 + +F + L A R++ + + +++ PSFA+ WL+P LS F YPGI + Sbjct: 67 QSYFLDIKEIFSQLTEATRKLQARSAKGALTVSLLPSFAIHWLVPRLSSFNSAYPGIDVR 126 Query: 127 VVTSTATVGKAGSSFDIAVRRGETNWPETLKVQRFMEDELVLVASPALLQA-MPLEDVSG 185 + K D+A+ G NWP L+V++ + L+ V SP LL PL+ Sbjct: 127 IQAVDRQEDKLADDVDVAIFYGRGNWP-GLRVEKLYAEYLLPVCSPLLLTGEKPLKTPED 185 Query: 186 LARHTVLLSRSRRNDWEDWRKLAGLKRSRSQAMLHFDHVHFVLQAVVDGLGVALSPVSLA 245 LA+HT+L SRR DW+ + + GL Q F H VLQA + G GVAL+ +A Sbjct: 186 LAKHTLLHDASRR-DWQTYTRQLGLNHINVQQGPIFSHSAMVLQAAIHGQGVALANNVMA 244 Query: 246 DNDLRSGRLVCPFPDLRLTLAPYYLGINAQAGSEAQL-----FARWL 287 +++ +GRLVCPF D+ ++ +YL + S+A+L F +W+ Sbjct: 245 QSEIEAGRLVCPFNDVLVSKNAFYLVCH---DSQAELGKIAAFRQWI 288 >ZgcvA [K] COG0583 Transcriptional regulator EcZ Escherichia coli O157:H7 EDL933 Length = 305 Score = 195 bits (496), Expect = 9e-50, Method: Compositional matrix adjust. Identities = 114/287 (39%), Positives = 163/287 (56%), Gaps = 11/287 (3%) Query: 7 PLNAIRAFLAAARHQSFTLAAHELNVTHGAISRQIKNLEGYLGMPLFERRTRQVLLTERG 66 PLNA+R F AAARH SFT AA EL VT A+S QIK+LE +LG+ LF RR R +LLTE G Sbjct: 7 PLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSLEDFLGLKLFRRRNRSLLLTEEG 66 Query: 67 RQFFEEASPALEILANAARRVMRDAPTRTVVINVRPSFAVRWLIPHLSDFVERYPGIAPQ 126 + +F + L A R++ + + +++ PSFA+ WL+P LS F YPGI + Sbjct: 67 QSYFLDIKEIFSQLTEATRKLQARSAKGALTVSLLPSFAIHWLVPRLSSFNSAYPGIDVR 126 Query: 127 VVTSTATVGKAGSSFDIAVRRGETNWPETLKVQRFMEDELVLVASPALLQA-MPLEDVSG 185 + K D+A+ G NWP L+V++ + L+ V SP LL PL+ Sbjct: 127 IQAVDRQEDKLADDVDVAIFYGRGNWP-GLRVEKLYAEYLLPVCSPLLLTGEKPLKTPED 185 Query: 186 LARHTVLLSRSRRNDWEDWRKLAGLKRSRSQAMLHFDHVHFVLQAVVDGLGVALSPVSLA 245 LA+HT+L SRR DW+ + + GL Q F H VLQA + G GVAL+ +A Sbjct: 186 LAKHTLLHDASRR-DWQTYTRQLGLNHINVQQGPIFSHSAMVLQAAIHGQGVALANNVMA 244 Query: 246 DNDLRSGRLVCPFPDLRLTLAPYYLGINAQAGSEAQL-----FARWL 287 +++ +GRLVCPF D+ ++ +YL + S+A+L F +W+ Sbjct: 245 QSEIEAGRLVCPFNDVLVSKNAFYLVCH---DSQAELGKIAAFRQWI 288 >ECs3668 [K] COG0583 Transcriptional regulator Ecs Escherichia coli O157:H7 Length = 305 Score = 195 bits (496), Expect = 9e-50, Method: Compositional matrix adjust. Identities = 114/287 (39%), Positives = 163/287 (56%), Gaps = 11/287 (3%) Query: 7 PLNAIRAFLAAARHQSFTLAAHELNVTHGAISRQIKNLEGYLGMPLFERRTRQVLLTERG 66 PLNA+R F AAARH SFT AA EL VT A+S QIK+LE +LG+ LF RR R +LLTE G Sbjct: 7 PLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSLEDFLGLKLFRRRNRSLLLTEEG 66 Query: 67 RQFFEEASPALEILANAARRVMRDAPTRTVVINVRPSFAVRWLIPHLSDFVERYPGIAPQ 126 + +F + L A R++ + + +++ PSFA+ WL+P LS F YPGI + Sbjct: 67 QSYFLDIKEIFSQLTEATRKLQARSAKGALTVSLLPSFAIHWLVPRLSSFNSAYPGIDVR 126 Query: 127 VVTSTATVGKAGSSFDIAVRRGETNWPETLKVQRFMEDELVLVASPALLQA-MPLEDVSG 185 + K D+A+ G NWP L+V++ + L+ V SP LL PL+ Sbjct: 127 IQAVDRQEDKLADDVDVAIFYGRGNWP-GLRVEKLYAEYLLPVCSPLLLTGEKPLKTPED 185 Query: 186 LARHTVLLSRSRRNDWEDWRKLAGLKRSRSQAMLHFDHVHFVLQAVVDGLGVALSPVSLA 245 LA+HT+L SRR DW+ + + GL Q F H VLQA + G GVAL+ +A Sbjct: 186 LAKHTLLHDASRR-DWQTYTRQLGLNHINVQQGPIFSHSAMVLQAAIHGQGVALANNVMA 244 Query: 246 DNDLRSGRLVCPFPDLRLTLAPYYLGINAQAGSEAQL-----FARWL 287 +++ +GRLVCPF D+ ++ +YL + S+A+L F +W+ Sbjct: 245 QSEIEAGRLVCPFNDVLVSKNAFYLVCH---DSQAELGKIAAFRQWI 288 >STM2982 [K] COG0583 Transcriptional regulator Sty Salmonella typhimurium LT2 Length = 305 Score = 194 bits (494), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 113/287 (39%), Positives = 164/287 (57%), Gaps = 11/287 (3%) Query: 7 PLNAIRAFLAAARHQSFTLAAHELNVTHGAISRQIKNLEGYLGMPLFERRTRQVLLTERG 66 PLNA+R F AAARH SFT AA EL VT A+S QIK+LE +LG+ LF RR R +LLTE G Sbjct: 7 PLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSLEDFLGLKLFRRRNRSLLLTEEG 66 Query: 67 RQFFEEASPALEILANAARRVMRDAPTRTVVINVRPSFAVRWLIPHLSDFVERYPGIAPQ 126 + +F + L A R++ + + +++ PSFA++WL+P LS F YPGI + Sbjct: 67 QSYFLDIKEIFSQLTEATRKLQARSAKGALTVSLPPSFAIQWLVPRLSSFNSAYPGIDVR 126 Query: 127 VVTSTATVGKAGSSFDIAVRRGETNWPETLKVQRFMEDELVLVASPALLQA-MPLEDVSG 185 + K D+A+ G NWP L+V++ + L+ V SP LL PL+ Sbjct: 127 IQAVDRQEDKLADDVDVAIFYGRGNWP-GLRVEKLYAEYLLPVCSPLLLTGEKPLKTPED 185 Query: 186 LARHTVLLSRSRRNDWEDWRKLAGLKRSRSQAMLHFDHVHFVLQAVVDGLGVALSPVSLA 245 LA+HT+L SRR DW+ + + GL Q F H VLQA + G G+AL+ +A Sbjct: 186 LAKHTLLHDASRR-DWQAYTRQLGLNHINVQQGPIFSHSAMVLQAAIHGQGIALANNVMA 244 Query: 246 DNDLRSGRLVCPFPDLRLTLAPYYLGINAQAGSEAQL-----FARWL 287 +++ +GRLVCPF D+ ++ +YL + S+A+L F +W+ Sbjct: 245 QSEIEAGRLVCPFNDVLVSKNAFYLVCH---DSQAELGKIAAFRQWI 288 >VC0896 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae Length = 306 Score = 180 bits (456), Expect = 4e-45, Method: Compositional matrix adjust. Identities = 104/284 (36%), Positives = 158/284 (55%), Gaps = 5/284 (1%) Query: 7 PLNAIRAFLAAARHQSFTLAAHELNVTHGAISRQIKNLEGYLGMPLFERRTRQVLLTERG 66 PLN+++ F AAARH SFT AA EL VT A+S QIK LE +LG+ LF RR R +LLTE G Sbjct: 7 PLNSLKVFEAAARHLSFTRAAEELFVTQAAVSHQIKALEEFLGLKLFRRRNRSLLLTEEG 66 Query: 67 RQFFEEASPALEILANAARRVMRDAPTRTVVINVRPSFAVRWLIPHLSDFVERYPGIAPQ 126 + +F + LA A +++ + + I++ PSFA++WL+P L+DF ++ P I + Sbjct: 67 QSYFLDIKDIFSSLAEATDKLLERSEKGALTISLPPSFAIQWLVPRLADFNQQEPDIDVR 126 Query: 127 VVTSTATVGKAGSSFDIAVRRGETNWPETLKVQRFMEDELVLVASPALLQA-MPLEDVSG 185 + G D+A+ G +WP L+ + ++ L+ + SPALL P+E +S Sbjct: 127 IKAVDMDEGSLTDDVDVAIYYGRGSWP-GLRADKLYQEFLIPLCSPALLLGNKPMEKLSD 185 Query: 186 LARHTVLLSRSRRNDWEDWRKLAGLKRSRSQAMLHFDHVHFVLQAVVDGLGVALSPVSLA 245 LA HT+L SR+ DW+ + K GL F H VLQA G GVAL LA Sbjct: 186 LAYHTLLHDTSRK-DWKQFAKENGLDNVNVNHGPIFSHSTMVLQAAAHGQGVALGNNVLA 244 Query: 246 DNDLRSGRLVCPFPDLRLTLAPYYLGINAQAGSEAQL--FARWL 287 ++ +GRL+ PF ++ +T +Y+ + + ++ F W+ Sbjct: 245 QPEIDAGRLIAPFDEVLMTNNAFYVVCHEKQADMGRIATFRDWM 288 >YPO1029 [K] COG0583 Transcriptional regulator Ype Yersinia pestis Length = 305 Score = 180 bits (456), Expect = 4e-45, Method: Compositional matrix adjust. Identities = 109/287 (37%), Positives = 162/287 (56%), Gaps = 11/287 (3%) Query: 7 PLNAIRAFLAAARHQSFTLAAHELNVTHGAISRQIKNLEGYLGMPLFERRTRQVLLTERG 66 PLNA+RAF AAARH SFT AA EL VT A+S QIK+LE +LG+ LF RR R +LLTE G Sbjct: 7 PLNALRAFDAAARHLSFTKAAEELFVTQAAVSHQIKSLEDFLGLKLFRRRNRSLLLTEEG 66 Query: 67 RQFFEEASPALEILANAARRVMRDAPTRTVVINVRPSFAVRWLIPHLSDFVERYPGIAPQ 126 + ++ + + A R++ + + +++ PSFA++WL+P LS F YPGI + Sbjct: 67 QSYYLDIKEIFTSINEATRKLQARSAKGALTVSLPPSFAIQWLVPRLSGFNAAYPGIDVR 126 Query: 127 VVTSTATVGKAGSSFDIAVRRGETNWPETLKVQRFMEDELVLVASPALLQAMP-LEDVSG 185 + K D+A+ G NW L+ +R + L+ V +P+LL L+ S Sbjct: 127 IQAVDREEDKLADDVDVAIFYGRGNW-SGLRTERLYAEFLLPVCAPSLLTGENGLKVPSD 185 Query: 186 LARHTVLLSRSRRNDWEDWRKLAGLKRSRSQAMLHFDHVHFVLQAVVDGLGVALSPVSLA 245 LA HT+L SRR DW + + G+ + Q F H V+QA V G G+AL +A Sbjct: 186 LANHTLLHDTSRR-DWLAYTRQLGVPQINVQQGPIFSHSAMVVQAAVHGQGIALVNNVMA 244 Query: 246 DNDLRSGRLVCPFPDLRLTLAPYYLGINAQAGSEAQL-----FARWL 287 +++ +GRLVCPF D+ ++ +YL + S+A+L F +W+ Sbjct: 245 QSEIEAGRLVCPFNDVLVSKNAFYLVCH---DSQAELGKIAAFRQWI 288 >PM0567 [K] COG0583 Transcriptional regulator Pmu Pasteurella multocida Length = 293 Score = 169 bits (429), Expect = 6e-42, Method: Compositional matrix adjust. Identities = 98/284 (34%), Positives = 152/284 (53%), Gaps = 3/284 (1%) Query: 7 PLNAIRAFLAAARHQSFTLAAHELNVTHGAISRQIKNLEGYLGMPLFERRTRQVLLTERG 66 PLN+++AF +AARH SFT AA EL VT AIS QIK LE +LG+ LF+R+ R + LTE G Sbjct: 7 PLNSLKAFESAARHLSFTKAAEELFVTQAAISHQIKLLEDFLGITLFKRKNRSLELTELG 66 Query: 67 RQFFEEASPALEILANAARRVMRDAPTRTVVINVRPSFAVRWLIPHLSDFVERYPGIAPQ 126 + +F + + L L A +++ + + I+V +F ++WL+PHLS+F +RYP I + Sbjct: 67 KAYFTDVNKILRRLVEATEKLLAQKNDKHLTISVPQTFGMQWLVPHLSEFNQRYPEIEVR 126 Query: 127 VVTSTATVGKAGSSFDIAVRRGETNWPETLKVQRFMEDELVLVASPALLQAMPLEDVSGL 186 + G DIA+ G+ NW + L+V++ +E+ L+++ASP LL P+ L Sbjct: 127 LKGVDQDEGVLNKDIDIAIYYGQGNW-DNLQVEKLVEENLLILASPKLLAHNPIHSKEDL 185 Query: 187 ARHTVLLSRSRRNDWEDWRKLAGLKRSRSQAMLHFDHVHFVLQAVVDGLGVALSPVSLAD 246 HT++ +R N W++ L+ Q F H LQA + G G+ L+ LA Sbjct: 186 KHHTLIHIHTRDN-WQNMANFLQLEDLNIQQGPLFSHTFMALQAAIHGQGLVLANRLLAQ 244 Query: 247 NDLRSGRLVCPFPDLRLTLAPYYLGINAQAGSE-AQLFARWLAE 289 ++ G L P +Y+ + E Q F W+ E Sbjct: 245 QEIDHGHLQIVLPTNLHDPKSFYVVNHFDVNDERIQAFRAWIIE 288 >mlr1832 [K] COG0583 Transcriptional regulator Mlo Mesorhizobium loti Length = 299 Score = 153 bits (387), Expect = 4e-37, Method: Compositional matrix adjust. Identities = 95/252 (37%), Positives = 142/252 (56%), Gaps = 4/252 (1%) Query: 7 PLNAIRAFLAAARHQSFTLAAHELNVTHGAISRQIKNLEGYLGMPLFERRTRQVLLTERG 66 PLNA+RAF A+ARH +F +AA ELNVT GA+++ I+ LE +LG LFER R + LT++G Sbjct: 10 PLNALRAFEASARHLNFRIAAEELNVTQGAVAQHIRGLETHLGTKLFERLPRGLALTDQG 69 Query: 67 RQFFEEASPALEILANAARRVMRDAPTRTVVINVRPSFAVRWLIPHLSDFVERYPGIAPQ 126 R + A ++++ A ++R P R + I+V PSFA +WLIP L DF+ P + + Sbjct: 70 RAYVPNIRRAFDLISEATL-LLRPEPAR-LTISVTPSFATKWLIPRLQDFMADNPLVDLR 127 Query: 127 VVTSTATVGKAGSSFDIAVRRGETNWPETLKVQRFMEDELVLVASPALLQAMPLEDVSGL 186 V+ S + DIAVR+G + L V +++ + SPALL A E + Sbjct: 128 VLASESLSSFQADGVDIAVRQGRPPFGAGLVVDLLFPQQIIAICSPALLPAGATEIPAAE 187 Query: 187 ARHTVLLSRSRRNDWEDW-RKLAGLKRSRSQAMLHFDHVHFVLQAVVDGLGVALSPVSLA 245 +H VLL + N W ++ K+ GLK + + F+ + A + G G+AL+ L Sbjct: 188 IQHHVLLHDA-HNLWPEFMEKVVGLKMTAELKRMRFNQTSLAIDAAIAGQGIALASRFLV 246 Query: 246 DNDLRSGRLVCP 257 DL +GRLV P Sbjct: 247 AADLAAGRLVQP 258 >CC1117 Non COG Length = 340 Score = 153 bits (387), Expect = 4e-37, Method: Compositional matrix adjust. Identities = 103/288 (35%), Positives = 146/288 (50%), Gaps = 8/288 (2%) Query: 7 PLNAIRAFLAAARHQSFTLAAHELNVTHGAISRQIKNLEGYLGMPLFERRTRQVLLTERG 66 PLNA+RAF AAARH +F+ AA EL+VT GA+S+QI+NLE Y+G LF+R + +LLT+ Sbjct: 34 PLNALRAFEAAARHLNFSRAADELSVTPGAVSQQIQNLEDYVGAALFKRTPKGLLLTDAA 93 Query: 67 RQFFEEASPALEILANAARRVMRDAPTRTVVINVRPSFAVRWLIPHLSDFVERYPGIAPQ 126 + A + LA AA + R + + PSFA +WL+P L F + +P + Sbjct: 94 QTALPALREAFDRLAEAASLLTAAVDGRRLTLTAAPSFAAKWLVPRLGKFEQAHPQVDVW 153 Query: 127 VVTSTATVGKAGSSFDIAVRRGETNWPETLKVQRFMEDELVLVASPALLQAMPLEDVSGL 186 + V A D+A+R G +P L+V R + + +V VASP LL+ LE L Sbjct: 154 LSAGMEVVDFATGEVDMAIRYGSGRYP-GLEVIRLLHETVVPVASPELLEQNALERPEDL 212 Query: 187 ARHTVLLSRS-----RRNDWEDWRKLAGLKRSRSQAMLHFDHVHFVLQAVVDGLGVALSP 241 H +L S DW W G++ F+ V++A +G G+AL+ Sbjct: 213 QHHILLHDGSPDADDSCPDWAMWLAARGIRGVDGARGPRFNQSSLVIEAAANGRGIALAK 272 Query: 242 VSLADNDLRSGRLVCPFPDLRLTLAPYYLGINAQAGSEAQL--FARWL 287 +LA DL SGRLV PF YY+ G Q+ F WL Sbjct: 273 RTLAQADLDSGRLVIPFEASTAVDFAYYVVHPKAKGRLPQVKAFVNWL 320 >mlr1973 [K] COG0583 Transcriptional regulator Mlo Mesorhizobium loti Length = 303 Score = 151 bits (382), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 107/266 (40%), Positives = 140/266 (52%), Gaps = 5/266 (1%) Query: 7 PLNAIRAFLAAARHQSFTLAAHELNVTHGAISRQIKNLEGYLGMPLFERRTRQVLLTERG 66 PL A+ AF AAARH SF+ AA ELN+THGA+SR I+N+E LG+ LF+R TR V LT G Sbjct: 7 PLTALPAFDAAARHLSFSRAADELNLTHGAVSRAIRNIEDRLGIQLFDRGTRSVRLTAVG 66 Query: 67 RQFFEEASPALEILANAARRVMRDAPTRTVVINVRPSFAVRWLIPHLSDFVERYPGIAPQ 126 + E AL+ +A A D TR + ++ FA RWL+P L F I + Sbjct: 67 AAYAVEVGKALDQIAAATIAATPDRSTRILNVSTSDGFAGRWLVPRLHRFHRANADIDVR 126 Query: 127 VVTSTATVGKAGSSFDIAVRRGETNWPETLKVQRFMEDELVL-VASPALLQAMPLEDVSG 185 + TS DIA+R G+ + T F+ DE V V SP LLQ + G Sbjct: 127 LATSGVLADFVSDGIDIAIRYGKGGY--TGVTAEFLADEEVFPVCSPELLQGEHPLRLPG 184 Query: 186 LARHTVLLSRSRRNDWEDWRKLAGLKRSRSQAMLHFDHVHFVLQAVVDGLGVALSPVSLA 245 RH L+ + R DW W + AG+ + + FD F ++A V G GV L +L Sbjct: 185 DLRHHKLIHDAFRIDWATWLQQAGVDGIDPKRGVRFDSATFAVEAAVHGEGVLLGRSALV 244 Query: 246 DNDLRSGRLVCPFPDLRL-TLAPYYL 270 DL +GRLV PF DL L + A YYL Sbjct: 245 SADLAAGRLVRPF-DLALKSAASYYL 269