BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0029.0062.p (1048 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1198 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia s... 1610 0.0 PA2527 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas ... 1449 0.0 YPO2848 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pe... 1444 0.0 yegN [V] COG0841 Cation/multidrug efflux pump Eco Escherichia co... 1386 0.0 ZyegN [V] COG0841 Cation/multidrug efflux pump EcZ Escherichia c... 1385 0.0 ECs2883 [V] COG0841 Cation/multidrug efflux pump Ecs Escherichia... 1385 0.0 STM2127 [V] COG0841 Cation/multidrug efflux pump Sty Salmonella ... 1372 0.0 RSp1199 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia s... 1095 0.0 XF2385 [V] COG0841 Cation/multidrug efflux pump Xfa Xylella fast... 1045 0.0 YPO2849 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pe... 1016 0.0 >RSp1198 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia solanacearum Length = 1041 Score = 1610 bits (4169), Expect = 0.0, Method: Compositional matrix adjust. Identities = 806/1040 (77%), Positives = 923/1040 (88%), Gaps = 1/1040 (0%) Query: 1 MNPSRQFILRPVATSLLMLAILLVGIVAYRLLPLSALPEVDYPTIQVVTLYPGASPDVMT 60 MNPSR FILRPVAT+LLM+AILL G+VAYR+LPLSALPEVDYPTIQV TLYPGASPDVMT Sbjct: 1 MNPSRIFILRPVATTLLMVAILLSGLVAYRMLPLSALPEVDYPTIQVTTLYPGASPDVMT 60 Query: 61 SSVTAPLERQFGQMPGLKQMSSTSSGGASVITLQFNLDLSLDIAEQEVQAAINAGSNLLP 120 SS+TAPLERQFGQMPGLKQM+S SSGGASVITLQF+L LSLDIAEQEVQAAINA NLLP Sbjct: 61 SSITAPLERQFGQMPGLKQMTSASSGGASVITLQFDLSLSLDIAEQEVQAAINAAGNLLP 120 Query: 121 SDLPMPPVYSKVNPADTPIITLAVTSSTMPLPKVQDLIDTRIAQKISQLSGVGLVSLSGG 180 +DLPMPP+YSKVNPAD PI+TLA+TS T+PLPK++D++DTR+AQK+SQL G+GLVS+SGG Sbjct: 121 TDLPMPPIYSKVNPADAPILTLAITSRTLPLPKLEDIVDTRVAQKLSQLPGIGLVSISGG 180 Query: 181 QRPAVRMQLNPRAVAALGLNLDDVRTAIGNANVNQAKGSFDGPTRASTIDANDQLRSADE 240 QRPAVR+Q N +A+AALGL++DD+RTAIGNANVN AKGSFDGP RASTIDANDQLRSA E Sbjct: 181 QRPAVRIQANTQALAALGLSIDDIRTAIGNANVNGAKGSFDGPMRASTIDANDQLRSAAE 240 Query: 241 YRNLIIAYKNGAPIRVSDVADVVDGAENVRLGAWANTQPAVIVNIQRQPGANVIAVVDSI 300 Y +I+AYKNGAPIR++DVA ++DGAEN +L AWANT PA+I+N+QRQPGANVI VV+ Sbjct: 241 YGTMIVAYKNGAPIRLTDVAQIIDGAENSKLAAWANTTPAIILNVQRQPGANVIDVVNRA 300 Query: 301 KKILPQLQASLPGAIDVHILTDRTTTIRASVDDVKFELLLSVALVVMVIFVFLRNVPATI 360 K +LPQL+ +LP IDV +LTDRTTTIRASV DV+FELLL+VALVVMVIF+FLRN+PATI Sbjct: 301 KALLPQLKDTLPANIDVAVLTDRTTTIRASVADVQFELLLAVALVVMVIFLFLRNIPATI 360 Query: 361 IPSVAVPLSLVGTFAIMYLAGFSINNLTLMALTIATGFVVDDAIVMIENISRYIEEGMKP 420 IP+VAVPLSLVGTF +MYLAGFS+NNLTLMALTIATGFVVDDAIVMIENI+RYIE+G P Sbjct: 361 IPAVAVPLSLVGTFGVMYLAGFSVNNLTLMALTIATGFVVDDAIVMIENIARYIEDGDPP 420 Query: 421 MQAALKGAEQIGFTIISLTFSLIAVLIPLLFMGDVVGRLFHEFAVTLAVSILISAVVSLT 480 M+AALKGA QIGFTIISLTFSLIAVLIPLLFM DVVGRLF EFA+TLAVSILISAVVSLT Sbjct: 421 MEAALKGARQIGFTIISLTFSLIAVLIPLLFMSDVVGRLFREFAITLAVSILISAVVSLT 480 Query: 481 LTPMMCARLLRHQPEEQQGWFYHKSQQFFDRIIARYGVMLQWVLARQKLTLLVAAATLGL 540 LTPMMCARLLRH PE +Q FYH + QFFD +IA+YG MLQWVL RQ+ TLLVA TL L Sbjct: 481 LTPMMCARLLRHIPEPEQTRFYHAAGQFFDNVIAQYGRMLQWVLDRQRTTLLVAIGTLAL 540 Query: 541 TVLLYVFVPKGFFPLQDTGVIQGISEATQSISFSAMGEKQQQLAKVVLQDPAVESLTSFI 600 T LLYV+VPKGFFP+QDTGVIQGIS+ATQSISF AM E+QQ+LA+V+L+DPAVESL+SFI Sbjct: 541 TGLLYVYVPKGFFPVQDTGVIQGISDATQSISFPAMAERQQKLAEVILKDPAVESLSSFI 600 Query: 601 GVDGTNATLNSGRMLINLKPHEVREVSATDVIRRLQGKLAAEVPGITLYMQPVQDLTIED 660 GVDGTN TLNSGRMLINLKP + R+ AT++I+RLQ +L A+V GI+L+MQPVQDLTIED Sbjct: 601 GVDGTNTTLNSGRMLINLKPKDARDADATEIIQRLQPEL-AKVGGISLFMQPVQDLTIED 659 Query: 661 SVSRTQYQFTLEDADPAVLSTWVPKLIARLQQQSELADVATNLQDQGLQAYIEIDRNAAS 720 VSRTQYQFT+ED DP LS WVP+L+ RLQQ EL DVA++LQD GL+AY++IDR+ A+ Sbjct: 660 RVSRTQYQFTVEDPDPNNLSKWVPRLVERLQQTGELRDVASDLQDNGLRAYVQIDRDKAA 719 Query: 721 RLGITTAAIDNALYNAFGQRLISTIYTQSNQYRVVMEVKPEFQHGPAALDSIYLVTSGGG 780 G+TTAA+D+ALY+A+GQRLISTI+TQSNQYRVV+E P+ Q GP +L + + ++GG Sbjct: 720 VYGVTTAAVDSALYSAYGQRLISTIFTQSNQYRVVLEAAPQLQKGPQSLYDLRVASTGGQ 779 Query: 781 KVPLSSIATVTERTAPLVVNHIGQFPAATVSFNLAKGASLGEAVKAIKAAEEEIGMPAST 840 +VPL + ATV E+ LVVNH GQFP+AT+SFNLA+GASLG AV AI AAE+ IG+PAS Sbjct: 780 QVPLGAFATVVEQPGSLVVNHQGQFPSATISFNLARGASLGAAVDAINAAEQAIGLPASM 839 Query: 841 VTNFQGAALAFQASLSNTLWLILAAIVTMYIVLGVLYESYIHPITILSTLPSAGVGALLS 900 T+FQGAALAFQ+SLSN LWLILAAI+TMYIVLGVLYES IHP+TILSTLPSAGVGALLS Sbjct: 840 QTSFQGAALAFQSSLSNELWLILAAIITMYIVLGVLYESTIHPVTILSTLPSAGVGALLS 899 Query: 901 LMISGTDLGIIGIIGIILLIGIVKKNAIMMIDFALEAERHEGKSPREAIYQACLLRFRPI 960 L++SG D+GII IIGIILLIGIVKKNAIMMIDFALEAER +G +PR+AIYQACLLRFRPI Sbjct: 900 LLVSGKDMGIIAIIGIILLIGIVKKNAIMMIDFALEAEREQGMAPRDAIYQACLLRFRPI 959 Query: 961 LMTTMAALLGALPLMLGTGVGSELRQPLGITMVGGLLVSQVLTLFTTPVIYLGFDSLGRR 1020 LMTTMAALLGALPLMLGTGVGSELRQPLGITMVGGLLVSQVLTLFTTPVIYL FDSLG R Sbjct: 960 LMTTMAALLGALPLMLGTGVGSELRQPLGITMVGGLLVSQVLTLFTTPVIYLAFDSLGHR 1019 Query: 1021 LRARFGQREPGPGGDDDEGK 1040 LR +R G D G Sbjct: 1020 LRDWRERRAARRTGADQSGS 1039 >PA2527 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas aeruginosa Length = 1043 Score = 1449 bits (3750), Expect = 0.0, Method: Compositional matrix adjust. Identities = 753/1044 (72%), Positives = 895/1044 (85%), Gaps = 5/1044 (0%) Query: 1 MNPSRQFILRPVATSLLMLAILLVGIVAYRLLPLSALPEVDYPTIQVVTLYPGASPDVMT 60 MNPSR FILRPVAT+LLM+AILL G++AYR LP+SALPEVDYPTIQVVTLYPGASP++MT Sbjct: 1 MNPSRPFILRPVATTLLMVAILLSGLIAYRFLPISALPEVDYPTIQVVTLYPGASPEIMT 60 Query: 61 SSVTAPLERQFGQMPGLKQMSSTSSGGASVITLQFNLDLSLDIAEQEVQAAINAGSNLLP 120 SS+TAPLE Q GQ+PGL +MSS+SSGGASVITLQF+L +LD+AEQEVQAAINA +LLP Sbjct: 61 SSITAPLENQLGQIPGLNEMSSSSSGGASVITLQFSLQSNLDVAEQEVQAAINAAQSLLP 120 Query: 121 SDLPMPPVYSKVNPADTPIITLAVTSSTMPLPKVQDLIDTRIAQKISQLSGVGLVSLSGG 180 +DLP PV+SKVNPAD PI+TLAV S MPLP++QDL+DTR+AQKISQ+SGVGLVS+SGG Sbjct: 121 NDLPNQPVFSKVNPADAPILTLAVMSDGMPLPQIQDLVDTRLAQKISQISGVGLVSISGG 180 Query: 181 QRPAVRMQLNPRAVAALGLNLDDVRTAIGNANVNQAKGSFDGPTRASTIDANDQLRSADE 240 QRPAVR++ NP A+AA GL+L+D+R+ + + N+N KGSFDGPTRAST+DANDQLRSAD Sbjct: 181 QRPAVRVRANPTALAAAGLSLEDLRSTVTSNNLNGPKGSFDGPTRASTLDANDQLRSADA 240 Query: 241 YRNLIIAYKNGAPIRVSDVADVVDGAENVRLGAWANTQPAVIVNIQRQPGANVIAVVDSI 300 YR+LIIAYKNG+P+R+ DVA V D AENVRL AWAN PAV++NIQRQPGANVI VVD I Sbjct: 241 YRDLIIAYKNGSPLRIRDVASVEDDAENVRLAAWANNLPAVVLNIQRQPGANVIEVVDRI 300 Query: 301 KKILPQLQASLPGAIDVHILTDRTTTIRASVDDVKFELLLSVALVVMVIFVFLRNVPATI 360 K +LPQLQ++LPG +DV +LTDRTTTIRASV DV+FEL L+VALVVMV F+FLRNV AT+ Sbjct: 301 KALLPQLQSTLPGNLDVQVLTDRTTTIRASVKDVQFELALAVALVVMVTFLFLRNVYATL 360 Query: 361 IPSVAVPLSLVGTFAIMYLAGFSINNLTLMALTIATGFVVDDAIVMIENISRYIEEGMKP 420 IPS AVPLSL+GTF +MYL+GFSINNLTLMALTIATGFVVDDAIVM+ENI+RY+E+G P Sbjct: 361 IPSFAVPLSLIGTFGVMYLSGFSINNLTLMALTIATGFVVDDAIVMVENIARYLEQGDSP 420 Query: 421 MQAALKGAEQIGFTIISLTFSLIAVLIPLLFMGDVVGRLFHEFAVTLAVSILISAVVSLT 480 ++AALKG++QIGFTIISLTFSLIAVLIPLLFMGDV GRLF EFA+TLAV+ILIS VSLT Sbjct: 421 LEAALKGSKQIGFTIISLTFSLIAVLIPLLFMGDVAGRLFREFAITLAVAILISGFVSLT 480 Query: 481 LTPMMCARLLRHQPEEQQGWFYHKSQQFFDRIIARYGVMLQWVLARQKLTLLVAAATLGL 540 LTPM+ A+LLRH E+QQG F + + D +IA+Y L+ VL Q LTLLVA ATL L Sbjct: 481 LTPMLSAKLLRHIDEDQQGRFARAAGRVIDGLIAQYAKALRVVLRHQPLTLLVAIATLAL 540 Query: 541 TVLLYVFVPKGFFPLQDTGVIQGISEATQSISFSAMGEKQQQLAKVVLQDPAVESLTSFI 600 T LLY+ +PKGFFP+QDTGVIQG++EA QSISF AM E+Q+ LA+VVL+DPAV SL+S+I Sbjct: 541 TALLYLAMPKGFFPVQDTGVIQGVAEAPQSISFQAMSERQRALAEVVLKDPAVASLSSYI 600 Query: 601 GVDGTNATLNSGRMLINLKPHEVREVSATDVIRRLQGKLAAEVPGITLYMQPVQDLTIED 660 GVDG+N TLN+GR+LINLKPH R+V+A++VI+RLQ +L +PGI LYMQPVQDLTIED Sbjct: 601 GVDGSNPTLNTGRLLINLKPHSERDVTASEVIQRLQPEL-DHLPGIKLYMQPVQDLTIED 659 Query: 661 SVSRTQYQFTLEDADPAVLSTWVPKLIARLQQQSELADVATNLQDQGLQAYIEIDRNAAS 720 V+RTQYQFTL+DADP VL+ WVPKL+ARLQ+ +LADVA++ QD+GLQAY+ IDR+ AS Sbjct: 660 RVARTQYQFTLQDADPDVLAEWVPKLVARLQELPQLADVASDWQDKGLQAYLNIDRDTAS 719 Query: 721 RLGITTAAIDNALYNAFGQRLISTIYTQSNQYRVVMEVKPEFQHGPAALDSIYLVTSGGG 780 RLG+ + ID+ LYNAFGQRLISTI+TQ+ QYRVV+EV P+FQ GP AL+ +Y+ +S G Sbjct: 720 RLGVKLSDIDSVLYNAFGQRLISTIFTQATQYRVVLEVAPQFQLGPQALEQLYVPSSDGT 779 Query: 781 KVPLSSIATVTERTAPLVVNHIGQFPAATVSFNLAKGASLGEAVKAIKAAEEEIGMPAST 840 +V LSS+A V ER L +NHI QFP+AT+SFNLAKG SLGEAV+AI+ E + +P S Sbjct: 780 QVRLSSLAKVEERHTLLAINHIAQFPSATLSFNLAKGYSLGEAVEAIRGVEASLELPLSM 839 Query: 841 VTNFQGAALAFQASLSNTLWLILAAIVTMYIVLGVLYESYIHPITILSTLPSAGVGALLS 900 +F+GAALAF+ASLSNTL LILA++VTMYIVLG+LYES+IHP+TILSTLPSAGVGALL+ Sbjct: 840 QGSFRGAALAFEASLSNTLLLILASVVTMYIVLGILYESFIHPVTILSTLPSAGVGALLA 899 Query: 901 LMISGTDLGIIGIIGIILLIGIVKKNAIMMIDFALEAERHEGKSPREAIYQACLLRFRPI 960 LM++G ++GI+ IIGIILLIGIVKKNAIMMIDFAL+AER+EGK P EAIYQACLLRFRPI Sbjct: 900 LMLAGQEIGIVAIIGIILLIGIVKKNAIMMIDFALDAERNEGKPPHEAIYQACLLRFRPI 959 Query: 961 LMTTMAALLGALPLMLGTGVGSELRQPLGITMVGGLLVSQVLTLFTTPVIYLGFDSLGRR 1020 LMTTMAALLGALPLML G G+ELRQPLGITMVGGLL+SQVLTLFTTPVIYL FD L RR Sbjct: 960 LMTTMAALLGALPLMLAGGAGAELRQPLGITMVGGLLLSQVLTLFTTPVIYLYFDRLARR 1019 Query: 1021 LRARFGQR----EPGPGGDDDEGK 1040 A QR G D D G+ Sbjct: 1020 WAAWRKQRGLDLNTEAGFDGDAGR 1043 >YPO2848 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pestis Length = 1052 Score = 1444 bits (3738), Expect = 0.0, Method: Compositional matrix adjust. Identities = 730/1027 (71%), Positives = 864/1027 (84%), Gaps = 1/1027 (0%) Query: 3 PSRQFILRPVATSLLMLAILLVGIVAYRLLPLSALPEVDYPTIQVVTLYPGASPDVMTSS 62 PSR FILRPVAT+L M+AILL GI+ YR LP+SALPEVDYPTIQVVTLYPGASPDV+TSS Sbjct: 12 PSRLFILRPVATTLFMIAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVVTSS 71 Query: 63 VTAPLERQFGQMPGLKQMSSTSSGGASVITLQFNLDLSLDIAEQEVQAAINAGSNLLPSD 122 +TAPLERQFGQM GLKQM+S SSGGASVITLQF L L LD+AEQEVQAAINA +NLLPSD Sbjct: 72 ITAPLERQFGQMSGLKQMASQSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSD 131 Query: 123 LPMPPVYSKVNPADTPIITLAVTSSTMPLPKVQDLIDTRIAQKISQLSGVGLVSLSGGQR 182 LP PP+Y+KVNPAD PI+TLAVT++ +P+ +V+D+++TRIAQKISQ++GVGLV+LSGGQR Sbjct: 132 LPYPPIYNKVNPADPPILTLAVTATAIPMTQVEDMVETRIAQKISQVTGVGLVTLSGGQR 191 Query: 183 PAVRMQLNPRAVAALGLNLDDVRTAIGNANVNQAKGSFDGPTRASTIDANDQLRSADEYR 242 PAVR++LN AVAALGL+ + +RTAI NANVN AKGS DGPTR+ T+ ANDQ++SA+EYR Sbjct: 192 PAVRVKLNAPAVAALGLDSETIRTAISNANVNSAKGSLDGPTRSVTLSANDQMKSAEEYR 251 Query: 243 NLIIAYKNGAPIRVSDVADVVDGAENVRLGAWANTQPAVIVNIQRQPGANVIAVVDSIKK 302 +LIIAY+NGAPIR+ DVA + GAEN +L AWANTQ A+++NIQRQPG NVIA DSI++ Sbjct: 252 DLIIAYQNGAPIRLQDVATIEQGAENNKLAAWANTQSAIVLNIQRQPGVNVIATADSIRE 311 Query: 303 ILPQLQASLPGAIDVHILTDRTTTIRASVDDVKFELLLSVALVVMVIFVFLRNVPATIIP 362 +LP+L SLP ++DV +LTDRT+TIRASV+DV+FELLL++ALVVMVI++FLRN ATIIP Sbjct: 312 MLPELIKSLPKSVDVKVLTDRTSTIRASVNDVQFELLLAIALVVMVIYLFLRNAAATIIP 371 Query: 363 SVAVPLSLVGTFAIMYLAGFSINNLTLMALTIATGFVVDDAIVMIENISRYIEEGMKPMQ 422 S+AVPLSLVGTFA MY GFSINNLTLMALTIATGFVVDDAIV+IENISRYIE+G KP+ Sbjct: 372 SIAVPLSLVGTFAAMYFLGFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLD 431 Query: 423 AALKGAEQIGFTIISLTFSLIAVLIPLLFMGDVVGRLFHEFAVTLAVSILISAVVSLTLT 482 AALKGA +IGFTIISLTFSLIAVLIPLLFM D+VGRLF EFAVTLAV+ILISAVVSLTLT Sbjct: 432 AALKGAGEIGFTIISLTFSLIAVLIPLLFMEDIVGRLFREFAVTLAVAILISAVVSLTLT 491 Query: 483 PMMCARLLRHQPEEQQGWFYHKSQQFFDRIIARYGVMLQWVLARQKLTLLVAAATLGLTV 542 PMMCAR+L ++ +Q S++FFD +IA Y V L+ VL LTL VA +TL LTV Sbjct: 492 PMMCARMLSYESLRKQNRLSRASEKFFDWVIAHYAVALKKVLNHPWLTLSVAFSTLVLTV 551 Query: 543 LLYVFVPKGFFPLQDTGVIQGISEATQSISFSAMGEKQQQLAKVVLQDPAVESLTSFIGV 602 +LY+ +PKGFFPLQD G+IQG EA QS+SFS M E+QQQ+A ++L+DPAVESLTSF+GV Sbjct: 552 ILYLLIPKGFFPLQDNGLIQGTLEAPQSVSFSNMAERQQQVAAIILKDPAVESLTSFVGV 611 Query: 603 DGTNATLNSGRMLINLKPHEVREVSATDVIRRLQGKLAAEVPGITLYMQPVQDLTIEDSV 662 DGTNATLN+GR+ INLKP R+ +I RLQ ++ VPGI LY+QPVQDLTI+ + Sbjct: 612 DGTNATLNNGRLQINLKPLSERDDRIPQIITRLQESVSG-VPGIKLYLQPVQDLTIDTQL 670 Query: 663 SRTQYQFTLEDADPAVLSTWVPKLIARLQQQSELADVATNLQDQGLQAYIEIDRNAASRL 722 SRTQYQFTL+ LSTWVPKL+ LQQ++ DV ++ QDQGL A++ +DR++ASRL Sbjct: 671 SRTQYQFTLQATSLEELSTWVPKLVNELQQKAPFQDVTSDWQDQGLVAFVNVDRDSASRL 730 Query: 723 GITTAAIDNALYNAFGQRLISTIYTQSNQYRVVMEVKPEFQHGPAALDSIYLVTSGGGKV 782 GIT AAIDNALYNAFGQRLISTIYTQSNQYRVV+E + G AA + I L G V Sbjct: 731 GITMAAIDNALYNAFGQRLISTIYTQSNQYRVVLEHDVQATPGLAAFNDIRLTGIDGKGV 790 Query: 783 PLSSIATVTERTAPLVVNHIGQFPAATVSFNLAKGASLGEAVKAIKAAEEEIGMPASTVT 842 PLSSIAT+ ER PL +NH+ QFP+ATVSFNLA+G SLGEAV A+ AE+EI +PA T Sbjct: 791 PLSSIATIEERFGPLSINHLNQFPSATVSFNLAQGYSLGEAVAAVTLAEKEIQLPADITT 850 Query: 843 NFQGAALAFQASLSNTLWLILAAIVTMYIVLGVLYESYIHPITILSTLPSAGVGALLSLM 902 FQG+ LAFQA+L +TLWLI+AAIV MYIVLGVLYES+IHPITILSTLP+AGVGALL+LM Sbjct: 851 RFQGSTLAFQAALGSTLWLIIAAIVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALM 910 Query: 903 ISGTDLGIIGIIGIILLIGIVKKNAIMMIDFALEAERHEGKSPREAIYQACLLRFRPILM 962 ++G +L +I IIGIILLIGIVKKNAIMMIDFAL AER +G +P +AIYQACLLRFRPILM Sbjct: 911 LTGNELDVIAIIGIILLIGIVKKNAIMMIDFALAAERDQGMTPYDAIYQACLLRFRPILM 970 Query: 963 TTMAALLGALPLMLGTGVGSELRQPLGITMVGGLLVSQVLTLFTTPVIYLGFDSLGRRLR 1022 TT+AAL GALPLML TGVG+ELRQPLG+ MVGGL+VSQVLTLFTTPVIYL FD L R R Sbjct: 971 TTLAALFGALPLMLSTGVGAELRQPLGVCMVGGLIVSQVLTLFTTPVIYLLFDKLARNTR 1030 Query: 1023 ARFGQRE 1029 + R+ Sbjct: 1031 GKNRHRD 1037 >yegN [V] COG0841 Cation/multidrug efflux pump Eco Escherichia coli K12 Length = 1040 Score = 1386 bits (3588), Expect = 0.0, Method: Compositional matrix adjust. Identities = 714/1027 (69%), Positives = 862/1027 (83%), Gaps = 1/1027 (0%) Query: 3 PSRQFILRPVATSLLMLAILLVGIVAYRLLPLSALPEVDYPTIQVVTLYPGASPDVMTSS 62 PSR FI+RPVAT+LLM+AILL GI+ YR LP+SALPEVDYPTIQVVTLYPGASPDVMTS+ Sbjct: 12 PSRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSA 71 Query: 63 VTAPLERQFGQMPGLKQMSSTSSGGASVITLQFNLDLSLDIAEQEVQAAINAGSNLLPSD 122 VTAPLERQFGQM GLKQMSS SSGGASVITLQF L L LD+AEQEVQAAINA +NLLPSD Sbjct: 72 VTAPLERQFGQMSGLKQMSSQSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSD 131 Query: 123 LPMPPVYSKVNPADTPIITLAVTSSTMPLPKVQDLIDTRIAQKISQLSGVGLVSLSGGQR 182 LP PPVYSKVNPAD PI+TLAVTS+ MP+ +V+D+++TR+AQKISQ+SGVGLV+LSGGQR Sbjct: 132 LPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETRVAQKISQISGVGLVTLSGGQR 191 Query: 183 PAVRMQLNPRAVAALGLNLDDVRTAIGNANVNQAKGSFDGPTRASTIDANDQLRSADEYR 242 PAVR++LN +A+AALGL + VRTAI ANVN AKGS DGP+RA T+ ANDQ++SA+EYR Sbjct: 192 PAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEEYR 251 Query: 243 NLIIAYKNGAPIRVSDVADVVDGAENVRLGAWANTQPAVIVNIQRQPGANVIAVVDSIKK 302 LIIAY+NGAPIR+ DVA V GAEN LGAWAN + A+++N+QRQPGAN+I+ DSI++ Sbjct: 252 QLIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQ 311 Query: 303 ILPQLQASLPGAIDVHILTDRTTTIRASVDDVKFELLLSVALVVMVIFVFLRNVPATIIP 362 +LPQL SLP ++ V +L+DRTT IRASVDD +FEL++++ALVVM+I++FLRN+PATIIP Sbjct: 312 MLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIP 371 Query: 363 SVAVPLSLVGTFAIMYLAGFSINNLTLMALTIATGFVVDDAIVMIENISRYIEEGMKPMQ 422 VAVPLSL+GTFA+M FSINNLTLMALTIATGFVVDDAIV+IENISRYIE+G KP+ Sbjct: 372 GVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLA 431 Query: 423 AALKGAEQIGFTIISLTFSLIAVLIPLLFMGDVVGRLFHEFAVTLAVSILISAVVSLTLT 482 AALKGA +IGFTIISLTFSLIAVLIPLLFMGD+VGRLF EFA+TLAV+ILISAVVSLTLT Sbjct: 432 AALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLT 491 Query: 483 PMMCARLLRHQPEEQQGWFYHKSQQFFDRIIARYGVMLQWVLARQKLTLLVAAATLGLTV 542 PMMCAR+L + +Q F S++ FDRIIA YG L VL LTL VA +TL L+V Sbjct: 492 PMMCARMLSQESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSV 551 Query: 543 LLYVFVPKGFFPLQDTGVIQGISEATQSISFSAMGEKQQQLAKVVLQDPAVESLTSFIGV 602 LL+VF+PKGFFP+QD G+IQG +A QS SF+ M ++Q+Q+A V+LQDPAV+SLTSF+GV Sbjct: 552 LLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGV 611 Query: 603 DGTNATLNSGRMLINLKPHEVREVSATDVIRRLQGKLAAEVPGITLYMQPVQDLTIEDSV 662 DGTN +LNS R+ INLKP + R+ VI RLQ + +VPG+ L++QP QDLTI+ V Sbjct: 612 DGTNPSLNSARLQINLKPLDERDDRVQKVIARLQTAV-DKVPGVDLFLQPTQDLTIDTQV 670 Query: 663 SRTQYQFTLEDADPAVLSTWVPKLIARLQQQSELADVATNLQDQGLQAYIEIDRNAASRL 722 SRTQYQFTL+ LSTWVP+L+ +LQQ +L+DV+++ QD+GL AY+ +DR++ASRL Sbjct: 671 SRTQYQFTLQATSLDALSTWVPQLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRL 730 Query: 723 GITTAAIDNALYNAFGQRLISTIYTQSNQYRVVMEVKPEFQHGPAALDSIYLVTSGGGKV 782 GI+ A +DNALYNAFGQRLISTIYTQ+NQYRVV+E E G AALD+I L +S GG V Sbjct: 731 GISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVV 790 Query: 783 PLSSIATVTERTAPLVVNHIGQFPAATVSFNLAKGASLGEAVKAIKAAEEEIGMPASTVT 842 PLSSIA + +R APL +NH+ QFP T+SFN+ SLG+AV+AI E+ + +P T Sbjct: 791 PLSSIAKIEQRFAPLSINHLDQFPVTTISFNVPDNYSLGDAVQAIMDTEKTLNLPVDITT 850 Query: 843 NFQGAALAFQASLSNTLWLILAAIVTMYIVLGVLYESYIHPITILSTLPSAGVGALLSLM 902 FQG+ LAFQ++L +T+WLI+AA+V MYIVLG+LYES+IHPITILSTLP+AGVGALL+L+ Sbjct: 851 QFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALL 910 Query: 903 ISGTDLGIIGIIGIILLIGIVKKNAIMMIDFALEAERHEGKSPREAIYQACLLRFRPILM 962 I+G++L +I IIGIILLIGIVKKNAIMMIDFAL AER +G SPREAIYQACLLRFRPILM Sbjct: 911 IAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPREAIYQACLLRFRPILM 970 Query: 963 TTMAALLGALPLMLGTGVGSELRQPLGITMVGGLLVSQVLTLFTTPVIYLGFDSLGRRLR 1022 TT+AALLGALPLML TGVG+ELR+PLGI MVGGL+VSQVLTLFTTPVIYL FD L + Sbjct: 971 TTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRLALWTK 1030 Query: 1023 ARFGQRE 1029 +RF + E Sbjct: 1031 SRFARHE 1037 >ZyegN [V] COG0841 Cation/multidrug efflux pump EcZ Escherichia coli O157:H7 EDL933 Length = 1040 Score = 1385 bits (3584), Expect = 0.0, Method: Compositional matrix adjust. Identities = 713/1027 (69%), Positives = 862/1027 (83%), Gaps = 1/1027 (0%) Query: 3 PSRQFILRPVATSLLMLAILLVGIVAYRLLPLSALPEVDYPTIQVVTLYPGASPDVMTSS 62 PSR FI+RPVAT+LLM+AILL GI+ YR LP+SALPEVDYPTIQVVTLYPGASPDVMTS+ Sbjct: 12 PSRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSA 71 Query: 63 VTAPLERQFGQMPGLKQMSSTSSGGASVITLQFNLDLSLDIAEQEVQAAINAGSNLLPSD 122 VTAPLERQFGQM GLKQMSS SSGGASVITLQF L L LD+AEQEVQAAINA +NLLPSD Sbjct: 72 VTAPLERQFGQMSGLKQMSSQSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSD 131 Query: 123 LPMPPVYSKVNPADTPIITLAVTSSTMPLPKVQDLIDTRIAQKISQLSGVGLVSLSGGQR 182 LP PPVYSKVNPAD PI+TLAVTS+ MP+ +V+D+++TR+AQKISQ+SGVGLV+LSGGQR Sbjct: 132 LPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETRVAQKISQISGVGLVTLSGGQR 191 Query: 183 PAVRMQLNPRAVAALGLNLDDVRTAIGNANVNQAKGSFDGPTRASTIDANDQLRSADEYR 242 PAVR++LN +A+AALGL + VRTAI ANVN AKGS DGP+RA T+ ANDQ++SA+EYR Sbjct: 192 PAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEEYR 251 Query: 243 NLIIAYKNGAPIRVSDVADVVDGAENVRLGAWANTQPAVIVNIQRQPGANVIAVVDSIKK 302 LIIAY+NGAPIR+ DVA V GAEN LGAWAN + A+++N+QRQPGAN+I+ DSI++ Sbjct: 252 QLIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQ 311 Query: 303 ILPQLQASLPGAIDVHILTDRTTTIRASVDDVKFELLLSVALVVMVIFVFLRNVPATIIP 362 +LPQL SLP ++ V +L+DRTT IRASVDD +FEL++++ALVVM+I++FLRN+PATIIP Sbjct: 312 MLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIP 371 Query: 363 SVAVPLSLVGTFAIMYLAGFSINNLTLMALTIATGFVVDDAIVMIENISRYIEEGMKPMQ 422 VAVPLSL+GTFA+M FSINNLTLMALTIATGFVVDDAIV+IENISRYIE+G KP+ Sbjct: 372 GVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLA 431 Query: 423 AALKGAEQIGFTIISLTFSLIAVLIPLLFMGDVVGRLFHEFAVTLAVSILISAVVSLTLT 482 AALKGA +IGFTIISLTFSLIAVLIPLLFMGD+VGRLF EFA+TLAV+ILISAVVSLTLT Sbjct: 432 AALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLT 491 Query: 483 PMMCARLLRHQPEEQQGWFYHKSQQFFDRIIARYGVMLQWVLARQKLTLLVAAATLGLTV 542 PMMCAR+L + +Q F S++ FDRIIA YG L VL LTL VA +TL L+V Sbjct: 492 PMMCARMLSQESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSV 551 Query: 543 LLYVFVPKGFFPLQDTGVIQGISEATQSISFSAMGEKQQQLAKVVLQDPAVESLTSFIGV 602 LL+VF+PKGFFP+QD G+IQG +A QS SF+ M ++Q+Q+A V+LQDPAV+SLTSF+GV Sbjct: 552 LLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGV 611 Query: 603 DGTNATLNSGRMLINLKPHEVREVSATDVIRRLQGKLAAEVPGITLYMQPVQDLTIEDSV 662 DGTN +LNS R+ INLKP + R+ VI RLQ + +VPG+ L++QP QDLTI+ V Sbjct: 612 DGTNPSLNSARLQINLKPLDERDDRVQKVIARLQTAV-DKVPGVDLFLQPTQDLTIDTQV 670 Query: 663 SRTQYQFTLEDADPAVLSTWVPKLIARLQQQSELADVATNLQDQGLQAYIEIDRNAASRL 722 SRTQYQFTL+ LSTWVP+L+ +LQQ +++DV+++ QD+GL AY+ +DR++ASRL Sbjct: 671 SRTQYQFTLQATSLDALSTWVPQLMEKLQQLPQISDVSSDWQDKGLVAYVNVDRDSASRL 730 Query: 723 GITTAAIDNALYNAFGQRLISTIYTQSNQYRVVMEVKPEFQHGPAALDSIYLVTSGGGKV 782 GI+ A +DNALYNAFGQRLISTIYTQ+NQYRVV+E E G AALD+I L +S GG V Sbjct: 731 GISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVV 790 Query: 783 PLSSIATVTERTAPLVVNHIGQFPAATVSFNLAKGASLGEAVKAIKAAEEEIGMPASTVT 842 PLSSIA + +R APL +NH+ QFP T+SFN+ SLG+AV+AI E+ + +P T Sbjct: 791 PLSSIAKIEQRFAPLSINHLDQFPVTTISFNVPDNYSLGDAVQAIMDTEKTLNLPVDITT 850 Query: 843 NFQGAALAFQASLSNTLWLILAAIVTMYIVLGVLYESYIHPITILSTLPSAGVGALLSLM 902 FQG+ LAFQ++L +T+WLI+AA+V MYIVLG+LYES+IHPITILSTLP+AGVGALL+LM Sbjct: 851 QFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALM 910 Query: 903 ISGTDLGIIGIIGIILLIGIVKKNAIMMIDFALEAERHEGKSPREAIYQACLLRFRPILM 962 I+G++L +I IIGIILLIGIVKKNAIMMIDFAL AER +G SPR+AIYQACLLRFRPILM Sbjct: 911 IAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPRDAIYQACLLRFRPILM 970 Query: 963 TTMAALLGALPLMLGTGVGSELRQPLGITMVGGLLVSQVLTLFTTPVIYLGFDSLGRRLR 1022 TT+AALLGALPLML TGVG+ELR+PLGI MVGGL+VSQVLTLFTTPVIYL FD L + Sbjct: 971 TTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRLALWTK 1030 Query: 1023 ARFGQRE 1029 +RF + E Sbjct: 1031 SRFARHE 1037 >ECs2883 [V] COG0841 Cation/multidrug efflux pump Ecs Escherichia coli O157:H7 Length = 1040 Score = 1385 bits (3584), Expect = 0.0, Method: Compositional matrix adjust. Identities = 713/1027 (69%), Positives = 862/1027 (83%), Gaps = 1/1027 (0%) Query: 3 PSRQFILRPVATSLLMLAILLVGIVAYRLLPLSALPEVDYPTIQVVTLYPGASPDVMTSS 62 PSR FI+RPVAT+LLM+AILL GI+ YR LP+SALPEVDYPTIQVVTLYPGASPDVMTS+ Sbjct: 12 PSRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSA 71 Query: 63 VTAPLERQFGQMPGLKQMSSTSSGGASVITLQFNLDLSLDIAEQEVQAAINAGSNLLPSD 122 VTAPLERQFGQM GLKQMSS SSGGASVITLQF L L LD+AEQEVQAAINA +NLLPSD Sbjct: 72 VTAPLERQFGQMSGLKQMSSQSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSD 131 Query: 123 LPMPPVYSKVNPADTPIITLAVTSSTMPLPKVQDLIDTRIAQKISQLSGVGLVSLSGGQR 182 LP PPVYSKVNPAD PI+TLAVTS+ MP+ +V+D+++TR+AQKISQ+SGVGLV+LSGGQR Sbjct: 132 LPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETRVAQKISQISGVGLVTLSGGQR 191 Query: 183 PAVRMQLNPRAVAALGLNLDDVRTAIGNANVNQAKGSFDGPTRASTIDANDQLRSADEYR 242 PAVR++LN +A+AALGL + VRTAI ANVN AKGS DGP+RA T+ ANDQ++SA+EYR Sbjct: 192 PAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEEYR 251 Query: 243 NLIIAYKNGAPIRVSDVADVVDGAENVRLGAWANTQPAVIVNIQRQPGANVIAVVDSIKK 302 LIIAY+NGAPIR+ DVA V GAEN LGAWAN + A+++N+QRQPGAN+I+ DSI++ Sbjct: 252 QLIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQ 311 Query: 303 ILPQLQASLPGAIDVHILTDRTTTIRASVDDVKFELLLSVALVVMVIFVFLRNVPATIIP 362 +LPQL SLP ++ V +L+DRTT IRASVDD +FEL++++ALVVM+I++FLRN+PATIIP Sbjct: 312 MLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIP 371 Query: 363 SVAVPLSLVGTFAIMYLAGFSINNLTLMALTIATGFVVDDAIVMIENISRYIEEGMKPMQ 422 VAVPLSL+GTFA+M FSINNLTLMALTIATGFVVDDAIV+IENISRYIE+G KP+ Sbjct: 372 GVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLA 431 Query: 423 AALKGAEQIGFTIISLTFSLIAVLIPLLFMGDVVGRLFHEFAVTLAVSILISAVVSLTLT 482 AALKGA +IGFTIISLTFSLIAVLIPLLFMGD+VGRLF EFA+TLAV+ILISAVVSLTLT Sbjct: 432 AALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLT 491 Query: 483 PMMCARLLRHQPEEQQGWFYHKSQQFFDRIIARYGVMLQWVLARQKLTLLVAAATLGLTV 542 PMMCAR+L + +Q F S++ FDRIIA YG L VL LTL VA +TL L+V Sbjct: 492 PMMCARMLSQESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSV 551 Query: 543 LLYVFVPKGFFPLQDTGVIQGISEATQSISFSAMGEKQQQLAKVVLQDPAVESLTSFIGV 602 LL+VF+PKGFFP+QD G+IQG +A QS SF+ M ++Q+Q+A V+LQDPAV+SLTSF+GV Sbjct: 552 LLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGV 611 Query: 603 DGTNATLNSGRMLINLKPHEVREVSATDVIRRLQGKLAAEVPGITLYMQPVQDLTIEDSV 662 DGTN +LNS R+ INLKP + R+ VI RLQ + +VPG+ L++QP QDLTI+ V Sbjct: 612 DGTNPSLNSARLQINLKPLDERDDRVQKVIARLQTAV-DKVPGVDLFLQPTQDLTIDTQV 670 Query: 663 SRTQYQFTLEDADPAVLSTWVPKLIARLQQQSELADVATNLQDQGLQAYIEIDRNAASRL 722 SRTQYQFTL+ LSTWVP+L+ +LQQ +++DV+++ QD+GL AY+ +DR++ASRL Sbjct: 671 SRTQYQFTLQATSLDALSTWVPQLMEKLQQLPQISDVSSDWQDKGLVAYVNVDRDSASRL 730 Query: 723 GITTAAIDNALYNAFGQRLISTIYTQSNQYRVVMEVKPEFQHGPAALDSIYLVTSGGGKV 782 GI+ A +DNALYNAFGQRLISTIYTQ+NQYRVV+E E G AALD+I L +S GG V Sbjct: 731 GISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVV 790 Query: 783 PLSSIATVTERTAPLVVNHIGQFPAATVSFNLAKGASLGEAVKAIKAAEEEIGMPASTVT 842 PLSSIA + +R APL +NH+ QFP T+SFN+ SLG+AV+AI E+ + +P T Sbjct: 791 PLSSIAKIEQRFAPLSINHLDQFPVTTISFNVPDNYSLGDAVQAIMDTEKTLNLPVDITT 850 Query: 843 NFQGAALAFQASLSNTLWLILAAIVTMYIVLGVLYESYIHPITILSTLPSAGVGALLSLM 902 FQG+ LAFQ++L +T+WLI+AA+V MYIVLG+LYES+IHPITILSTLP+AGVGALL+LM Sbjct: 851 QFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALM 910 Query: 903 ISGTDLGIIGIIGIILLIGIVKKNAIMMIDFALEAERHEGKSPREAIYQACLLRFRPILM 962 I+G++L +I IIGIILLIGIVKKNAIMMIDFAL AER +G SPR+AIYQACLLRFRPILM Sbjct: 911 IAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPRDAIYQACLLRFRPILM 970 Query: 963 TTMAALLGALPLMLGTGVGSELRQPLGITMVGGLLVSQVLTLFTTPVIYLGFDSLGRRLR 1022 TT+AALLGALPLML TGVG+ELR+PLGI MVGGL+VSQVLTLFTTPVIYL FD L + Sbjct: 971 TTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRLALWTK 1030 Query: 1023 ARFGQRE 1029 +RF + E Sbjct: 1031 SRFARHE 1037 >STM2127 [V] COG0841 Cation/multidrug efflux pump Sty Salmonella typhimurium LT2 Length = 1040 Score = 1372 bits (3551), Expect = 0.0, Method: Compositional matrix adjust. Identities = 705/1027 (68%), Positives = 854/1027 (83%), Gaps = 1/1027 (0%) Query: 3 PSRQFILRPVATSLLMLAILLVGIVAYRLLPLSALPEVDYPTIQVVTLYPGASPDVMTSS 62 PSR FILRPVAT+LLM AILL GI+ YR LP++ALPEVDYPTIQVVTLYPGASPDVMTS+ Sbjct: 12 PSRLFILRPVATTLLMAAILLAGIIGYRFLPVAALPEVDYPTIQVVTLYPGASPDVMTSA 71 Query: 63 VTAPLERQFGQMPGLKQMSSTSSGGASVITLQFNLDLSLDIAEQEVQAAINAGSNLLPSD 122 VTAPLERQFGQM GLKQMSS SSGGASV+TLQF L L LD+AEQEVQAAINA +NLLPSD Sbjct: 72 VTAPLERQFGQMSGLKQMSSQSSGGASVVTLQFQLTLPLDVAEQEVQAAINAATNLLPSD 131 Query: 123 LPMPPVYSKVNPADTPIITLAVTSSTMPLPKVQDLIDTRIAQKISQLSGVGLVSLSGGQR 182 LP PP+YSKVNPAD PI+TLAVTS++MP+ +V+D+++TR+AQKISQ+SGVGLV+L+GGQR Sbjct: 132 LPNPPIYSKVNPADPPIMTLAVTSNSMPMTQVEDMVETRVAQKISQVSGVGLVTLAGGQR 191 Query: 183 PAVRMQLNPRAVAALGLNLDDVRTAIGNANVNQAKGSFDGPTRASTIDANDQLRSADEYR 242 PAVR++LN +AVAALGL + VRTAI ANVN AKGS DGP RA T+ ANDQ++SADEYR Sbjct: 192 PAVRVKLNAQAVAALGLTSETVRTAITGANVNSAKGSLDGPERAVTLSANDQMQSADEYR 251 Query: 243 NLIIAYKNGAPIRVSDVADVVDGAENVRLGAWANTQPAVIVNIQRQPGANVIAVVDSIKK 302 LIIAY+NGAP+R+ DVA V GAEN LGAWAN PA+++N+QRQPGAN+IA DSI++ Sbjct: 252 RLIIAYQNGAPVRLGDVATVEQGAENSWLGAWANQAPAIVMNVQRQPGANIIATADSIRQ 311 Query: 303 ILPQLQASLPGAIDVHILTDRTTTIRASVDDVKFELLLSVALVVMVIFVFLRNVPATIIP 362 +LPQL SLP ++ V +L+DRTT IRASV D +FEL+L++ALVVM+I++FLRN+PATIIP Sbjct: 312 MLPQLTESLPKSVKVTVLSDRTTNIRASVRDTQFELMLAIALVVMIIYLFLRNIPATIIP 371 Query: 363 SVAVPLSLVGTFAIMYLAGFSINNLTLMALTIATGFVVDDAIVMIENISRYIEEGMKPMQ 422 VAVPLSL+GTFA+M FSINNLTLMALTIATGFVVDDAIV+IENISRYIE+G KP+ Sbjct: 372 GVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLA 431 Query: 423 AALKGAEQIGFTIISLTFSLIAVLIPLLFMGDVVGRLFHEFAVTLAVSILISAVVSLTLT 482 AALKGA +IGFTIISLTFSLIAVLIPLLFMGD+VGRLF EFAVTLAV+ILISAVVSLTLT Sbjct: 432 AALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAILISAVVSLTLT 491 Query: 483 PMMCARLLRHQPEEQQGWFYHKSQQFFDRIIARYGVMLQWVLARQKLTLLVAAATLGLTV 542 PMMCAR+L Q +Q F ++ FDR+IA YG L VL LTL VA ATL L+V Sbjct: 492 PMMCARMLSQQSLRKQNRFSRACERMFDRVIASYGRGLAKVLNHPWLTLSVAFATLLLSV 551 Query: 543 LLYVFVPKGFFPLQDTGVIQGISEATQSISFSAMGEKQQQLAKVVLQDPAVESLTSFIGV 602 +L++ +PKGFFP+QD G+IQG +A QS S+++M ++Q+Q+A+ +LQDPAV+SLT+F+GV Sbjct: 552 MLWIVIPKGFFPVQDNGIIQGTLQAPQSSSYASMAQRQRQVAERILQDPAVQSLTTFVGV 611 Query: 603 DGTNATLNSGRMLINLKPHEVREVSATDVIRRLQGKLAAEVPGITLYMQPVQDLTIEDSV 662 DG N TLNS R+ INLKP + R+ VI RLQ +A +PG+ LY+QP QDLTI+ V Sbjct: 612 DGANPTLNSARLQINLKPLDARDDRVQQVISRLQTAVAT-IPGVELYLQPTQDLTIDTQV 670 Query: 663 SRTQYQFTLEDADPAVLSTWVPKLIARLQQQSELADVATNLQDQGLQAYIEIDRNAASRL 722 SRTQYQFTL+ LS WVPKL LQ +L++V+++ QD+GL A++ +DR++ASRL Sbjct: 671 SRTQYQFTLQATTLDALSHWVPKLQNALQSLPQLSEVSSDWQDRGLAAWVNVDRDSASRL 730 Query: 723 GITTAAIDNALYNAFGQRLISTIYTQSNQYRVVMEVKPEFQHGPAALDSIYLVTSGGGKV 782 GI+ A +DNALYNAFGQRLISTIYTQ+NQYRVV+E G AAL++I L + GG V Sbjct: 731 GISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTASMPGLAALETIRLTSRDGGTV 790 Query: 783 PLSSIATVTERTAPLVVNHIGQFPAATVSFNLAKGASLGEAVKAIKAAEEEIGMPASTVT 842 PLS+IA + +R APL +NH+ QFP T SFN+ + SLG+AV+AI E+ + +PA T Sbjct: 791 PLSAIARIEQRFAPLSINHLDQFPVTTFSFNVPESYSLGDAVQAILDTEKTLALPADITT 850 Query: 843 NFQGAALAFQASLSNTLWLILAAIVTMYIVLGVLYESYIHPITILSTLPSAGVGALLSLM 902 FQG+ LAFQA+L +T+WLI+AA+V MYIVLGVLYES+IHPITILSTLP+AGVGALL+L+ Sbjct: 851 QFQGSTLAFQAALGSTVWLIVAAVVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALI 910 Query: 903 ISGTDLGIIGIIGIILLIGIVKKNAIMMIDFALEAERHEGKSPREAIYQACLLRFRPILM 962 I+G++L II IIGIILLIGIVKKNAIMMIDFAL AER +G SPR+AI+QACLLRFRPILM Sbjct: 911 IAGSELDIIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPRDAIFQACLLRFRPILM 970 Query: 963 TTMAALLGALPLMLGTGVGSELRQPLGITMVGGLLVSQVLTLFTTPVIYLGFDSLGRRLR 1022 TT+AALLGALPLML TGVG+ELR+PLGI MVGGLLVSQVLTLFTTPVIYL FD L ++ Sbjct: 971 TTLAALLGALPLMLSTGVGTELRRPLGIAMVGGLLVSQVLTLFTTPVIYLLFDRLSLYVK 1030 Query: 1023 ARFGQRE 1029 +RF + + Sbjct: 1031 SRFPRHK 1037 >RSp1199 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia solanacearum Length = 1033 Score = 1095 bits (2833), Expect = 0.0, Method: Compositional matrix adjust. Identities = 569/1015 (56%), Positives = 737/1015 (72%), Gaps = 5/1015 (0%) Query: 1 MNPSRQFILRPVATSLLMLAILLVGIVAYRLLPLSALPEVDYPTIQVVTLYPGASPDVMT 60 MN S FI RPVAT+LL + + L GI A+ LLP+S LP+VD+PTI V PGASP+ M Sbjct: 1 MNLSATFIARPVATALLTIGVALAGIAAFNLLPVSPLPQVDFPTISVNASLPGASPETMA 60 Query: 61 SSVTAPLERQFGQMPGLKQMSSTSSGGASVITLQFNLDLSLDIAEQEVQAAINAGSNLLP 120 ++V PLER G++ G+ +M+S S+ G++ +TLQF+L +D A ++VQAAINA +LLP Sbjct: 61 ATVATPLERSLGRIAGITEMTSQSALGSTRVTLQFDLSRDIDGAARDVQAAINASRSLLP 120 Query: 121 SDLPMPPVYSKVNPADTPIITLAVTSSTMPLPKVQDLIDTRIAQKISQLSGVGLVSLSGG 180 S LP P Y KVNPAD PI+ L +TS T ++ D T +AQK+SQ++GVG V++ G Sbjct: 121 SGLPSNPTYRKVNPADAPIMILGLTSDTKSRGELYDAASTILAQKLSQITGVGQVNIGGA 180 Query: 181 QRPAVRMQLNPRAVAALGLNLDDVRTAIGNANVNQAKGSFDGPTRASTIDANDQLRSADE 240 PAVR++LNP A+ G++ + VRT I N N+ KG + R T+ ANDQ R A+E Sbjct: 181 SLPAVRVELNPTALNKYGISTETVRTVITATNANKPKGMLEAGNRVWTLYANDQARHAEE 240 Query: 241 YRNLIIAYKNGAPIRVSDVADVVDGAENVRLGAWANTQPAVIVNIQRQPGANVIAVVDSI 300 Y+ LIIAY+NGAP+R+SDVA+V D +++R AN +P+V++ I RQPGAN+I VD I Sbjct: 241 YKPLIIAYRNGAPVRLSDVAEVTDSVQDIRNYGSANGKPSVLLIINRQPGANIIDTVDRI 300 Query: 301 KKILPQLQASLPGAIDVHILTDRTTTIRASVDDVKFELLLSVALVVMVIFVFLRNVPATI 360 ILP L+ ++P I++ ++ DRT TIRAS+ DV+ L+LS+ LV+MV+++FLRN+ AT+ Sbjct: 301 NAILPYLRNTIPAQINLDVMMDRTPTIRASLRDVERTLMLSIGLVIMVVYLFLRNLRATL 360 Query: 361 IPSVAVPLSLVGTFAIMYLAGFSINNLTLMALTIATGFVVDDAIVMIENISRYIEEGMKP 420 IPSVAVP+SL+GTF +MYL G+S++NL+LMALT+ATGFVVDDAIV++EN+SR+IE GM+P Sbjct: 361 IPSVAVPVSLIGTFGVMYLCGYSLDNLSLMALTVATGFVVDDAIVVLENVSRHIENGMRP 420 Query: 421 MQAALKGAEQIGFTIISLTFSLIAVLIPLLFMGDVVGRLFHEFAVTLAVSILISAVVSLT 480 MQAALKGA ++GFT++S++FSLIAV IPLL MG +VGRLF EFAVTL+V+IL+S +SLT Sbjct: 421 MQAALKGAREVGFTVVSMSFSLIAVFIPLLMMGGIVGRLFREFAVTLSVAILVSLAISLT 480 Query: 481 LTPMMCARLLRHQPEEQQGWFYHKSQQFFDRIIARYGVMLQWVLARQKLTLLVAAATLGL 540 TPMMCARLL+ EE+ GWF+ K++ FF+ ++ Y L W L LTLL+ AT+ L Sbjct: 481 TTPMMCARLLKPASEEEPGWFHRKTEGFFNLLLDGYRHSLAWALRHSWLTLLILLATVCL 540 Query: 541 TVLLYVFVPKGFFPLQDTGVIQGISEATQSISFSAMGEKQQQLAKVVLQDPAVESLTSFI 600 LYV VPKGFFP QD G + G +A Q+ISF AM K +V QDPAVE++ F Sbjct: 541 NGYLYVVVPKGFFPQQDVGRLMGFIQADQAISFQAMRTKLVDFIHIVQQDPAVENVVGFT 600 Query: 601 GVDGTNATLNSGRMLINLKPHEVREVSATDVIRRLQGKLAAEVPGITLYMQPVQDLTIED 660 G + +NSG+M I LKP R++SA VI RL+GKLA E PG L++Q VQD+ I Sbjct: 601 G----GSQINSGQMFIQLKPLAERKLSADQVINRLRGKLARE-PGANLFLQAVQDIRIGG 655 Query: 661 SVSRTQYQFTLEDADPAVLSTWVPKLIARLQQQSELADVATNLQDQGLQAYIEIDRNAAS 720 S QYQ+TL+ + L W PK+ L Q L DV T+ QD+G Q + DR+ A Sbjct: 656 RPSNAQYQYTLQADNLEELRAWEPKIRQALTQIKSLVDVNTDAQDKGQQTALVFDRDKAM 715 Query: 721 RLGITTAAIDNALYNAFGQRLISTIYTQSNQYRVVMEVKPEFQHGPAALDSIYLVTSGGG 780 LGIT IDNAL NAFGQR +STIY NQYRVVME P++ P L IYL+T+ G Sbjct: 716 ALGITPKDIDNALNNAFGQRQVSTIYNPLNQYRVVMEAAPQYWQNPEGLRDIYLITASGA 775 Query: 781 KVPLSSIATVTERTAPLVVNHIGQFPAATVSFNLAKGASLGEAVKAIKAAEEEIGMPAST 840 +VPLS+ + PL VNH GQF A+T+SFNLA GASL A + I+ A IG+P + Sbjct: 776 QVPLSTFSHYGPTNTPLAVNHQGQFAASTLSFNLAPGASLSAATQQIQDAMNRIGVPTTV 835 Query: 841 VTNFQGAALAFQASLSNTLWLILAAIVTMYIVLGVLYESYIHPITILSTLPSAGVGALLS 900 +FQG A AFQ SLS+ LIL A++T+YIVLGVLYESY+HPITILSTLPSAGVGALL+ Sbjct: 836 HGSFQGTARAFQDSLSSQPVLILFALITIYIVLGVLYESYVHPITILSTLPSAGVGALLA 895 Query: 901 LMISGTDLGIIGIIGIILLIGIVKKNAIMMIDFALEAERHEGKSPREAIYQACLLRFRPI 960 L+++ TD +I +IG+ILLIGIVKKNAIMMIDFALEAER +G SP +AI+ AC+LRFRPI Sbjct: 896 LIVTDTDFSVIALIGVILLIGIVKKNAIMMIDFALEAERSQGMSPADAIFHACVLRFRPI 955 Query: 961 LMTTMAALLGALPLMLGTGVGSELRQPLGITMVGGLLVSQVLTLFTTPVIYLGFD 1015 LMTTMAALLGALPL LG G G+ELRQPLGI++VGGLLVSQ+LTL+TTPV+YL D Sbjct: 956 LMTTMAALLGALPLALGHGDGAELRQPLGISIVGGLLVSQILTLYTTPVVYLALD 1010 >XF2385 [V] COG0841 Cation/multidrug efflux pump Xfa Xylella fastidiosa 9a5c Length = 1077 Score = 1045 bits (2701), Expect = 0.0, Method: Compositional matrix adjust. Identities = 561/1062 (52%), Positives = 740/1062 (69%), Gaps = 47/1062 (4%) Query: 7 FILRPVATSLLMLAILLVGIVAYRLLPLSALPEVDYPTIQVVTLYPGASPDVMTSSVTAP 66 FI RP+ATSLLM +LL+GI+ Y+ LP+SALPEVD P++ V T YPGA+ M + VT P Sbjct: 13 FIRRPIATSLLMFGVLLLGILGYKKLPMSALPEVDAPSLVVTTQYPGANAKTMAALVTTP 72 Query: 67 LERQFGQMPGLKQMSSTSSGGASVITLQFNLDLSLDIAEQEVQAAINAGSNLLPSDLPMP 126 LE Q GQ+ GL MSS SS G S ITLQF+ +LDIA Q+VQAAI+ +LPS LP Sbjct: 73 LEHQLGQISGLDIMSSDSSAGLSTITLQFSTHKNLDIAAQDVQAAIHQA--ILPSALPHQ 130 Query: 127 PVYSKVNPADTPIITLAVTSSTMPLPKVQDLIDTRIAQKISQLSGVGLVSLSGGQRPAVR 186 P+Y++VNPAD IITL +TS T+PL ++ D +AQ++SQ+SGVGLVS++G RPAVR Sbjct: 131 PIYNRVNPADAAIITLKLTSDTLPLRELNTYADAILAQRLSQISGVGLVSIAGNVRPAVR 190 Query: 187 MQLNPRAVAALGLNLDDVRTAIGNANVNQAKGSFDGPTRASTIDANDQLRSADEYRNLII 246 +Q+NP ++ +GL ++ +R + ANVN KGS +G +++ +I NDQL+ A +YR+ II Sbjct: 191 IQVNPAQLSNMGLTMESLRNTLTQANVNAPKGSLNGKSQSYSIGTNDQLKDASQYRDTII 250 Query: 247 AYKNGAPIRVSDVADVVDGAENVRLGAWANTQPAVIVNIQRQPGANVIAVVDSIKKILPQ 306 Y+NG P+R+S+VADVVDG EN ++ AWAN +PAV++ I+RQPGAN+I V+ I+ ILPQ Sbjct: 251 HYQNGHPVRLSEVADVVDGVENDQISAWANAKPAVLLEIRRQPGANIIQTVEQIRAILPQ 310 Query: 307 LQASLPGAIDVHILTDRTTTIRASVDDVKFELLLSVALVVMVIFVFLRNVPATIIPSVAV 366 L+A LP + + + +DRT TIRASV +VKF LLL++ LVV VIFVFLR + AT+IPSVAV Sbjct: 311 LRAVLPTDVHLDVFSDRTETIRASVHEVKFTLLLTIGLVVAVIFVFLRRLWATLIPSVAV 370 Query: 367 PLSLVGTFAIMYLAGFSINNLTLMALTIATGFVVDDAIVMIENISRYIEEGMKPMQAALK 426 PLSL GTF++M G S++NL+LMAL +ATGFVVDDAIVMIENI RYIE+G +AA Sbjct: 371 PLSLAGTFSVMAFNGMSLDNLSLMALVVATGFVVDDAIVMIENIVRYIEQGKSGREAAEI 430 Query: 427 GAEQIGFTIISLTFSLIAVLIPLLFMGDVVGRLFHEFAVTLAVSILISAVVSLTLTPMMC 486 GA QIGFTI+SLT SL+AV +PLL M V GRLFHEFA L+ +++IS +VSLTLTPMMC Sbjct: 431 GARQIGFTILSLTISLVAVFLPLLLMPGVTGRLFHEFAWVLSTAVVISMLVSLTLTPMMC 490 Query: 487 ARLLRHQ--PEEQQGWFYHKSQQFFDRIIARYGVMLQWVLARQKLTLLVAAATLGLTVLL 544 A LL+ PE K + R +A Y L WVL Q+LTL+VA T+ LT++L Sbjct: 491 AYLLKPDTLPESDSPTPSTKI-TLWTRTVALYERTLDWVLMHQQLTLVVALVTVALTIVL 549 Query: 545 YVFVPKGFFPLQDTGVIQGISEATQSISFSAMGEKQQQLAKVVLQDPAVESLTSFIGVDG 604 YV +PKG P QDTG+I G+ +A Q I+FS M ++ + +A + +DPAV +++FIG Sbjct: 550 YVTIPKGLLPEQDTGLIIGVVQADQDIAFSQMEQRTRAVADALRKDPAVTGVSAFIGAGT 609 Query: 605 TNATLNSGRMLINLKPHEVREVSATDVIR-RLQGKLAAEVPGITLYMQPVQDLTIEDSVS 663 N TLN G++ I LKP RE + IR RLQ + AA +PGI LY++PVQD+T++ V+ Sbjct: 610 INPTLNHGQLSIVLKPRNQRE--GLNTIRPRLQ-RAAAGIPGIVLYLKPVQDVTLDTHVA 666 Query: 664 RTQYQFTLEDADPAVLSTWVPKLIARLQQQSELADVATNLQDQGLQAYIEIDRNAASRLG 723 T+YQ++L + D L+TW ++ ++Q L DV NL DQG I +DR+ AS LG Sbjct: 667 ATEYQYSLSNVDATELATWATRMTEAMRQIPALTDVDNNLADQGRALQITVDRDKASLLG 726 Query: 724 ITTAAIDNALYNAFGQRLISTIYTQSNQYRVVMEVKPEFQHGPAALDSIYLVTSGGGK-- 781 + I++ LY+AFGQR ISTI+T+ NQYRVV+EV P F+ A + + ++G G Sbjct: 727 VPMQTINDTLYDAFGQRQISTIFTELNQYRVVLEVAPHFRTSTALTQQLGVASNGSGALT 786 Query: 782 -----------------------------------VPLSSIATVTERTAPLVVNHIGQFP 806 +PLS++A AP V++H Q P Sbjct: 787 GSNATSFGQAVSSNSSTATGIGNRNTGMTVGTGRIIPLSALADAKVTNAPRVISHQQQLP 846 Query: 807 AATVSFNLAKGASLGEAVKAIKAAEEEIGMPASTVTNFQGAALAFQASLSNTLWLILAAI 866 A T+SFNLA+G SL AVKAI+ A ++ +P F G A+ F +S S+ +WL+LA+I Sbjct: 847 AVTISFNLAQGYSLSHAVKAIEQARTQLQIPPQVRVQFIGKAVEFTSSQSDIVWLLLASI 906 Query: 867 VTMYIVLGVLYESYIHPITILSTLPSAGVGALLSLMISGTDLGIIGIIGIILLIGIVKKN 926 V +YIVLGVLYESYIHP+TI+STLPSAGVGALL+LM+ G L + I+GI+LLIGIVKKN Sbjct: 907 VVIYIVLGVLYESYIHPLTIISTLPSAGVGALLALMLCGLSLSVDSIVGIVLLIGIVKKN 966 Query: 927 AIMMIDFALEAERHEGKSPREAIYQACLLRFRPILMTTMAALLGALPLMLGTGVGSELRQ 986 AIMMIDFA+EA R G S +AI +ACLLRFRPI+MTT AALLGALPL LG G+G+ELR+ Sbjct: 967 AIMMIDFAIEA-RSTGSSAHDAIRRACLLRFRPIIMTTAAALLGALPLALGDGIGAELRR 1025 Query: 987 PLGITMVGGLLVSQVLTLFTTPVIYLGFDSLGRRLRARFGQR 1028 PLGIT+VGGLL+SQ++TL+TTPVIYL F+ L RLR R Sbjct: 1026 PLGITIVGGLLLSQLITLYTTPVIYLFFERLSERLRLWRAHR 1067 >YPO2849 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pestis Length = 1024 Score = 1016 bits (2628), Expect = 0.0, Method: Compositional matrix adjust. Identities = 538/1025 (52%), Positives = 725/1025 (70%), Gaps = 16/1025 (1%) Query: 7 FILRPVATSLLMLAILLVGIVAYRLLPLSALPEVDYPTIQVVTLYPGASPDVMTSSVTAP 66 FI RPVAT+LL LAI L GI+ + LLP+S LP+VDYP I V PGA P+ M SSV P Sbjct: 7 FIQRPVATTLLTLAITLSGIIGFSLLPVSPLPQVDYPVIMVSASMPGADPETMASSVATP 66 Query: 67 LERQFGQMPGLKQMSSTSSGGASVITLQFNLDLSLDIAEQEVQAAINAGSNLLPSDLPMP 126 LER G++ G+ +M+STSS G++ I LQF+L+ ++ A ++VQAA+NA +LLPS +P Sbjct: 67 LERALGRIAGVNEMTSTSSLGSTRIILQFDLNRDINGAARDVQAALNAAQSLLPSGMPSR 126 Query: 127 PVYSKVNPADTPIITLAVTSSTMPLPKVQDLIDTRIAQKISQLSGVGLVSLSGGQRPAVR 186 P Y K+NP+D PI+ + +TS T ++ D T++AQKI+Q GV V++ G PAVR Sbjct: 127 PTYRKMNPSDAPIMIMTLTSDTFSQGQLYDYASTKLAQKIAQTEGVSDVTVGGSSLPAVR 186 Query: 187 MQLNPRAVAALGLNLDDVRTAIGNANVNQAKGSFDGPTRASTIDANDQLRSADEYRNLII 246 ++LNP A+ G++LD VR AI ANV + +GS D + AND++++A+ YR LI+ Sbjct: 187 VELNPSALFNQGVSLDAVRQAISAANVRRPQGSVDAAETHWQVQANDEIKTAEGYRPLIV 246 Query: 247 AYKNGAPIRVSDVADVVDGAENVRLGAWANTQPAVIVNIQRQPGANVIAVVDSIKKILPQ 306 Y NG+P+R+ DVA+V+D ++VR + QPAV++ I R+PGAN+IA VD I+ LP Sbjct: 247 HYNNGSPVRLQDVANVIDSVQDVRNAGMSAGQPAVLLVISREPGANIIATVDRIRAELPA 306 Query: 307 LQASLPGAIDVHILTDRTTTIRASVDDVKFELLLSVALVVMVIFVFLRNVPATIIPSVAV 366 L+AS+P +I ++I DR+ TIRAS+D+V+ L+++VALV++V+F+FLR+ AT+IP+VAV Sbjct: 307 LRASIPASIQLNIAQDRSPTIRASLDEVERSLVIAVALVILVVFIFLRSGRATLIPAVAV 366 Query: 367 PLSLVGTFAIMYLAGFSINNLTLMALTIATGFVVDDAIVMIENISRYIEEGMKPMQAALK 426 P+SL+GTFA MYL GFS+NNL+LMALTIATGFVVDDAIV++ENISR++E G+KP AAL+ Sbjct: 367 PVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENISRHLEAGVKPKVAALR 426 Query: 427 GAEQIGFTIISLTFSLIAVLIPLLFMGDVVGRLFHEFAVTLAVSILISAVVSLTLTPMMC 486 G ++GFT++S++ SL+AV IPLL M + GRLF EFAVTL+V+I IS V+SLTLTPMMC Sbjct: 427 GVREVGFTVLSMSISLVAVFIPLLLMAGLPGRLFREFAVTLSVAIGISLVISLTLTPMMC 486 Query: 487 ARLLRHQPEEQQGWFYHKSQQFFDRIIA---RYGVMLQWVLARQKLTLLVAAATLGLTVL 543 A LLR P+ QQ + + F ++A YG L W L+ + ++V +T+ L V Sbjct: 487 AWLLRSHPKGQQ----QRIRGFGKVLLAIQQGYGRSLNWALSHTRWVMVVLLSTIALNVW 542 Query: 544 LYVFVPKGFFPLQDTGVIQGISEATQSISFSAMGEKQQQLAKVVLQDPAVESLTSFIGVD 603 LY+ +PK FFP QDTG + G +A QSISF +M +K + ++V DPAV+S+T F G Sbjct: 543 LYISIPKTFFPEQDTGRMMGFIQADQSISFQSMQQKLKDFMQIVGADPAVDSVTGFTGGS 602 Query: 604 GTNATLNSGRMLINLKPHEVREVSATDVIRRLQGKLAAEVPGITLYMQPVQDLTIEDSVS 663 T NSG M I+LKP R+ +A VI RL+GKLA E PG L++ VQD+ + S Sbjct: 603 RT----NSGSMFISLKPLSERQETAQQVITRLRGKLAKE-PGANLFLSSVQDIRVGGRHS 657 Query: 664 RTQYQFTLEDADPAVLSTWVPKLIARLQQQSELADVATNLQDQGLQAYIEIDRNAASRLG 723 YQFTL D A L W PK+ A L + +LADV ++ QD+G + + DR +RLG Sbjct: 658 NAAYQFTLLADDLAALREWEPKVRAALAKLPQLADVNSDQQDKGAEMALTYDRETMARLG 717 Query: 724 ITTAAIDNALYNAFGQRLISTIYTQSNQYRVVMEVKPEFQHGPAALDSIYLVTSGGGKVP 783 I + + L NAFGQR ISTIY NQY+VVMEV PE+ ++LD ++++ S G +P Sbjct: 718 IDVSEANALLNNAFGQRQISTIYQPLNQYKVVMEVAPEYTQDVSSLDKMFVINSNGQSIP 777 Query: 784 LSSIATVTERTAPLVVNHIGQFPAATVSFNLAKGASLGEAVKAIKAAEEEIGMPASTVTN 843 LS A APL VNH G A+T+SFNL G SL EA A++ A E+G+P++ Sbjct: 778 LSYFAKWQPANAPLAVNHQGLSAASTISFNLPDGGSLSEATAAVERAMTELGVPSTVRGA 837 Query: 844 FQGAALAFQASLSNTLWLILAAIVTMYIVLGVLYESYIHPITILSTLPSAGVGALLSLMI 903 F G A FQ +L + LWLI+AAI T+YIVLG+LYESY+HP+TILSTLPSAGVGALL+L + Sbjct: 838 FAGTAQVFQETLKSQLWLIMAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALEL 897 Query: 904 SGTDLGIIGIIGIILLIGIVKKNAIMMIDFALEAERHEGKSPREAIYQACLLRFRPILMT 963 +I +IGI+LLIGIVKKNAIMM+DFAL+A+R+ S REAI+QA LLRFRPI+MT Sbjct: 898 FDAPFSLIALIGIMLLIGIVKKNAIMMVDFALDAQRNGNISAREAIFQASLLRFRPIIMT 957 Query: 964 TMAALLGALPLMLGTGVGSELRQPLGITMVGGLLVSQVLTLFTTPVIYLGFDSLGRRLRA 1023 T+AAL GALPL+L +G G+ELRQPLGIT+VGGL+VSQ+LTL+TTPVIYL FD RLR Sbjct: 958 TLAALFGALPLVLSSGDGAELRQPLGITIVGGLVVSQLLTLYTTPVIYLYFD----RLRN 1013 Query: 1024 RFGQR 1028 RF ++ Sbjct: 1014 RFSKQ 1018