BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0028.0003.p (560 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ECs4620 [R] COG4146 Predicted symporter Ecs Escherichia coli O15... 433 e-121 ZyidK [R] COG4146 Predicted symporter EcZ Escherichia coli O157:... 432 e-121 yidK [R] COG4146 Predicted symporter Eco Escherichia coli K12 432 e-120 PM0597 Non COG 421 e-117 BH2222 [R] COG4146 Predicted symporter Bha Bacillus halodurans 413 e-115 VCA0667 [ER] COG0591 Na+/proline symporter Vch Vibrio cholerae 91 7e-18 SA0303 [ER] COG0591 Na+/proline symporter Sau Staphylococcus aur... 86 2e-16 SP1328 [ER] COG0591 Na+/proline symporter Spn Streptococcus pneu... 85 4e-16 sll1087 [ER] COG0591 Na+/proline symporter Syn Synechocystis 80 1e-14 BH2706 [ER] COG0591 Na+/proline symporter Bha Bacillus halodurans 76 2e-13 >ECs4620 [R] COG4146 Predicted symporter Ecs Escherichia coli O157:H7 Length = 571 Score = 433 bits (1114), Expect = e-121, Method: Compositional matrix adjust. Identities = 229/545 (42%), Positives = 344/545 (63%), Gaps = 13/545 (2%) Query: 8 RAKDVGAR-GYFMASGGLNGWFIAGSMMLTNLSVEQLVGLNGDAYAHNLSAMAWECTAAI 66 R D G++ GYF+A L IA S+MLTNLS EQLVGL+G AY +S M WE T+A+ Sbjct: 25 RKTDTGSQQGYFLAGRSLKAPVIAASLMLTNLSTEQLVGLSGQAYKSGMSVMGWEVTSAV 84 Query: 67 STVALAMFFLPRYLRGGFSTLPQFLEERFDATTRRVVSAFFVISYMLVVNPSGLYLGAIT 126 + + LA+ FLPRYL+ G +T+P FLEER+D TTR ++ F+I+ + P LY GA+ Sbjct: 85 TLIFLALIFLPRYLKRGIATIPDFLEERYDKTTRMIIDFCFLIATGVCFLPIVLYSGALA 144 Query: 127 FNQVFGVQQAFGASYPVTITGLVWISGFIGALYAVFGGLRAVAVSDTINGVGLLIAGLMV 186 N +F V ++ S+ I LV + G G LYAV GGLRA+AV+D+ING+GL+I GLMV Sbjct: 145 LNSLFHVGESLQISHGAAIWLLVILLGLAGILYAVIGGLRAMAVADSINGIGLVIGGLMV 204 Query: 187 PALGLLALGHGDFFAGVHVIATAAPEKLSAIGGPHDSVPFGTVFTGMIFANLFYWCTNQA 246 P GL+A+G G F G+ I T EKL+++GGP D +P G FTG+I N FYWCTNQ Sbjct: 205 PVFGLIAMGKGSFMQGIEQITTVHAEKLNSVGGPTDPLPIGAAFTGLILVNTFYWCTNQG 264 Query: 247 IIQRTFAAKNLAEGQKGVLLSGLLKLMVPIVMLMPGVIAYHLYAGNPLARPDLAYPQLVA 306 I+QRT A+K+LAEGQKG LL+ +LK++ P+V+++PG+IA+HLY P + D+AYP LV Sbjct: 265 IVQRTLASKSLAEGQKGALLTAVLKMLDPLVLVLPGLIAFHLYQDLP--KADMAYPTLVN 322 Query: 307 DLLPWWAKGFFVAVLFGTVMSHFNAVINSTATLIAFDFY-RVWKPEASDEKMIRVGKMAS 365 ++LP GFF AVLFG V+S FN +NS +TL + Y R+ A ++++ VG+ Sbjct: 323 NVLPVPLVGFFGAVLFGAVISTFNGFLNSASTLFSMGIYRRIINQNAEPQQLVTVGRKFG 382 Query: 366 IAVAVISLLIAPLLMFAPDGIYTVMRRFSGFFNIPIIAVVLMGFFNARIDALPAKIVLLL 425 +A++S+L+AP + AP G+Y+ M++ +G +N+P++ +++MGFF RI AL AK+ + + Sbjct: 383 FFIAIVSVLVAPWIANAPQGLYSWMKQLNGIYNVPLVTIIIMGFFFLRIPALAAKVAMGI 442 Query: 426 HVIAYTLLIFVFKVDSTYGIHFIHIMGMLFVTEVLLMLVLGQFFRRAQPYQAHIRQHGDL 485 +I+Y + ++ K D HF++++ F V++MLV+G RA P+ D+ Sbjct: 443 GIISYITINYLVKFD----FHFLYVLACTFCINVVVMLVIGFIKPRATPFTFKDAFAVDM 498 Query: 486 TPWRYASRMSVLLVALLVSVYLTFSPLGVARSGGVTQQYYLWMGLTWALAVLLLVVLRRR 545 PW+ S+ ++ ++ VY G+A GG ++ + A V++ ++ Sbjct: 499 KPWKNVKIASIGILFAMIGVY-----AGLAEFGGYGTRWLAMISYFIAAVVIVYLIFDSW 553 Query: 546 VHAAD 550 H D Sbjct: 554 RHRHD 558 >ZyidK [R] COG4146 Predicted symporter EcZ Escherichia coli O157:H7 EDL933 Length = 571 Score = 432 bits (1112), Expect = e-121, Method: Compositional matrix adjust. Identities = 229/545 (42%), Positives = 343/545 (62%), Gaps = 13/545 (2%) Query: 8 RAKDVGAR-GYFMASGGLNGWFIAGSMMLTNLSVEQLVGLNGDAYAHNLSAMAWECTAAI 66 R D G++ GYF+A L IA S+MLTNLS EQLVGL+G AY +S M WE T+A+ Sbjct: 25 RKTDTGSQQGYFLAGRSLKAPVIAASLMLTNLSTEQLVGLSGQAYKSGMSVMGWEVTSAV 84 Query: 67 STVALAMFFLPRYLRGGFSTLPQFLEERFDATTRRVVSAFFVISYMLVVNPSGLYLGAIT 126 + + LA+ FLPRYL+ G +T+P FLEER+D TTR ++ F+I+ + P LY GA+ Sbjct: 85 TLIFLALIFLPRYLKRGIATIPDFLEERYDKTTRMIIDFCFLIATGVCFLPIVLYSGALA 144 Query: 127 FNQVFGVQQAFGASYPVTITGLVWISGFIGALYAVFGGLRAVAVSDTINGVGLLIAGLMV 186 N +F V ++ S+ I LV + G G LYAV GGLRA+AV+D+ING+GL+I GLMV Sbjct: 145 LNSLFHVGESLQISHGAAIWLLVILLGLAGILYAVIGGLRAMAVADSINGIGLVIGGLMV 204 Query: 187 PALGLLALGHGDFFAGVHVIATAAPEKLSAIGGPHDSVPFGTVFTGMIFANLFYWCTNQA 246 P GL+A+G G F G+ I T EKL+++GGP D +P G FTG+I N FYWCTNQ Sbjct: 205 PVFGLIAMGKGSFMQGIEQITTVHAEKLNSVGGPTDPLPIGAAFTGLILVNTFYWCTNQG 264 Query: 247 IIQRTFAAKNLAEGQKGVLLSGLLKLMVPIVMLMPGVIAYHLYAGNPLARPDLAYPQLVA 306 I+QRT A+K+LAEGQKG LL+ +LK++ P+V+++PG+IA+HLY P + D+AYP LV Sbjct: 265 IVQRTLASKSLAEGQKGALLTAVLKMLDPLVLVLPGLIAFHLYQDLP--KADMAYPTLVN 322 Query: 307 DLLPWWAKGFFVAVLFGTVMSHFNAVINSTATLIAFDFY-RVWKPEASDEKMIRVGKMAS 365 ++LP GFF AVLFG V+S FN +NS +TL Y R+ A ++++ VG+ Sbjct: 323 NVLPVPLVGFFGAVLFGAVISTFNGFLNSASTLFXMGIYRRIINQNAEPQQLVTVGRKFG 382 Query: 366 IAVAVISLLIAPLLMFAPDGIYTVMRRFSGFFNIPIIAVVLMGFFNARIDALPAKIVLLL 425 +A++S+L+AP + AP G+Y+ M++ +G +N+P++ +++MGFF RI AL AK+ + + Sbjct: 383 FFIAIVSVLVAPWIANAPQGLYSWMKQLNGIYNVPLVTIIIMGFFFLRIPALAAKVAMGI 442 Query: 426 HVIAYTLLIFVFKVDSTYGIHFIHIMGMLFVTEVLLMLVLGQFFRRAQPYQAHIRQHGDL 485 +I+Y + ++ K D HF++++ F V++MLV+G RA P+ D+ Sbjct: 443 GIISYITINYLVKFD----FHFLYVLACTFCINVVVMLVIGFIKPRATPFTFKDAFAVDM 498 Query: 486 TPWRYASRMSVLLVALLVSVYLTFSPLGVARSGGVTQQYYLWMGLTWALAVLLLVVLRRR 545 PW+ S+ ++ ++ VY G+A GG ++ + A V++ ++ Sbjct: 499 KPWKNVKIASIGILFAMIGVY-----AGLAEFGGYGTRWLAMISYFIAAVVIVYLIFDSW 553 Query: 546 VHAAD 550 H D Sbjct: 554 RHRHD 558 >yidK [R] COG4146 Predicted symporter Eco Escherichia coli K12 Length = 571 Score = 432 bits (1111), Expect = e-120, Method: Compositional matrix adjust. Identities = 229/545 (42%), Positives = 344/545 (63%), Gaps = 13/545 (2%) Query: 8 RAKDVGAR-GYFMASGGLNGWFIAGSMMLTNLSVEQLVGLNGDAYAHNLSAMAWECTAAI 66 R D G++ GYF+A L IA S+MLTNLS EQLVGL+G AY +S M WE T+A+ Sbjct: 25 RKTDTGSQQGYFLAGRSLKAPVIAASLMLTNLSTEQLVGLSGQAYKSGMSVMGWEVTSAV 84 Query: 67 STVALAMFFLPRYLRGGFSTLPQFLEERFDATTRRVVSAFFVISYMLVVNPSGLYLGAIT 126 + + LA+ FLPRYL+ G +T+P FLEER+D TTR ++ F+I+ + P LY GA+ Sbjct: 85 TLIFLALIFLPRYLKRGIATIPDFLEERYDKTTRIIIDFCFLIATGVCFLPIVLYSGALA 144 Query: 127 FNQVFGVQQAFGASYPVTITGLVWISGFIGALYAVFGGLRAVAVSDTINGVGLLIAGLMV 186 N +F V ++ S+ I LV + G G LYAV GGLRA+AV+D+ING+GL+I GLMV Sbjct: 145 LNSLFHVGESLQISHGAAIWLLVILLGLAGILYAVIGGLRAMAVADSINGIGLVIGGLMV 204 Query: 187 PALGLLALGHGDFFAGVHVIATAAPEKLSAIGGPHDSVPFGTVFTGMIFANLFYWCTNQA 246 P GL+A+G G F G+ + T EKL++IGGP D +P G FTG+I N FYWCTNQ Sbjct: 205 PVFGLIAMGKGSFMQGIEQLTTVHAEKLNSIGGPTDPLPIGAAFTGLILVNTFYWCTNQG 264 Query: 247 IIQRTFAAKNLAEGQKGVLLSGLLKLMVPIVMLMPGVIAYHLYAGNPLARPDLAYPQLVA 306 I+QRT A+K+LAEGQKG LL+ +LK++ P+V+++PG+IA+HLY P + D+AYP LV Sbjct: 265 IVQRTLASKSLAEGQKGALLTAVLKMLDPLVLVLPGLIAFHLYQDLP--KADMAYPTLVN 322 Query: 307 DLLPWWAKGFFVAVLFGTVMSHFNAVINSTATLIAFDFY-RVWKPEASDEKMIRVGKMAS 365 ++LP GFF AVLFG V+S FN +NS +TL + Y R+ A ++++ VG+ Sbjct: 323 NVLPVPMVGFFGAVLFGAVISTFNGFLNSASTLFSMGIYRRIINQNAEPQQLVTVGRKFG 382 Query: 366 IAVAVISLLIAPLLMFAPDGIYTVMRRFSGFFNIPIIAVVLMGFFNARIDALPAKIVLLL 425 +A++S+L+AP + AP G+Y+ M++ +G +N+P++ +++MGFF RI AL AK+ + + Sbjct: 383 FFIAIVSVLVAPWIANAPQGLYSWMKQLNGIYNVPLVTIIIMGFFFPRIPALAAKVAMGI 442 Query: 426 HVIAYTLLIFVFKVDSTYGIHFIHIMGMLFVTEVLLMLVLGQFFRRAQPYQAHIRQHGDL 485 +I+Y + ++ K D HF++++ F V++MLV+G RA P+ D+ Sbjct: 443 GIISYITINYLVKFD----FHFLYVLACTFCINVVVMLVIGFIKPRATPFTFKDAFAVDM 498 Query: 486 TPWRYASRMSVLLVALLVSVYLTFSPLGVARSGGVTQQYYLWMGLTWALAVLLLVVLRRR 545 PW+ S+ ++ ++ VY G+A GG ++ + A V++ ++ Sbjct: 499 KPWKNVKIASIGILFAMIGVY-----AGLAEFGGYGTRWLAMISYFIAAVVIVYLIFDSW 553 Query: 546 VHAAD 550 H D Sbjct: 554 RHRHD 558 >PM0597 Non COG Length = 559 Score = 421 bits (1083), Expect = e-117, Method: Compositional matrix adjust. Identities = 232/548 (42%), Positives = 356/548 (64%), Gaps = 12/548 (2%) Query: 1 VSYLFTRRAKDVGARGYFMASGGLNGWFIAGSMMLTNLSVEQLVGLNGDAYAHNLSAMAW 60 +S+ T+ ++GYF+A GL+G I SM+LT+LS EQL+G+N +Y N S +AW Sbjct: 18 ISWKKTKNDDLSTSKGYFLAGRGLSGLVIGCSMVLTSLSTEQLIGVNAVSYKGNFSIIAW 77 Query: 61 ECTAAISTVALAMFFLPRYLRGGFSTLPQFLEERFDATTRRVVSAFFVISYMLVVNPSGL 120 + I LA++ LP+Y++ G++T+P+F E RFD TR ++SA F++ Y+ +V P+ L Sbjct: 78 TVQSVIPLCFLALYLLPKYIKNGYTTIPEFFENRFDRQTRLIMSALFLVFYLFIVIPTAL 137 Query: 121 YLGAITFNQVFGVQQAFGASYPVTITGLVWISGFIGALYAVFGGLRAVAVSDTINGVGLL 180 Y GAI FN++F ++ FG SY +I V G +GA+YA+FGGL+AVAVSDT+N V L+ Sbjct: 138 YTGAIAFNKIFNLETVFGISYGQSIVYTVMAIGVVGAIYAIFGGLKAVAVSDTVNAVLLV 197 Query: 181 IAGLMVPALGLLALGHGDFFAGVHVIATAAPEKLSAIGGPHDSVPFGTVFTGMIFANLFY 240 + L+VP L+ LG G AG I T EK +AIGG D+VP+ +FTG++ N FY Sbjct: 198 VGALLVPIFALIHLGDGSIAAGFKTITTTHVEKFNAIGGAEDAVPWPAIFTGILIVNFFY 257 Query: 241 WCTNQAIIQRTFAAKNLAEGQKGVLLSGLLKLMVPIVMLMPGVIAYHLYAGNPLARPDLA 300 W TNQAI+QR A++L GQKG+LL+ L L +P+++ +PG++++H+ G L D + Sbjct: 258 WTTNQAIVQRALGARDLKSGQKGILLAALFLLTLPLILNLPGLLSFHIL-GEGLNPIDTS 316 Query: 301 YPQLVADLLPWWAKGFFVAVLFGTVMSHFNAVINSTATLIAFDFY-RVWKPEASDEKMIR 359 YP LV +LP + +GFF+A LFG ++S FN+ +NS AT+ D + K + +++++I Sbjct: 317 YPALVNRVLPTFLQGFFIAALFGAILSTFNSFLNSAATIYCKDLLPSISKKQRTEKELIL 376 Query: 360 VGKMASIAVAVISLLIAPLLMFAPDGIYTVMRRFSGFFNIPIIAVVLMGFFNARIDALPA 419 K S +AV++++I PLLMF DGI+ + +RF+GF NIPI+A+ +G FN + L A Sbjct: 377 HAKKVSAIMAVLTMIIGPLLMFGTDGIFLLTKRFAGFVNIPIVALFAVGLFNKTVSGLAA 436 Query: 420 KIVLLLHVIAYTLLIFVFKVDSTYGIHFIHIMGMLFVTEVLLMLVLGQFFRRAQPYQA-- 477 +I LLLHVI Y +++VF+V ++F+++M LFV +V++MLVLGQF +R +PY+ Sbjct: 437 RIALLLHVILYFSIVWVFQVK----VNFVYVMAALFVFDVVVMLVLGQFLKR-EPYEESK 491 Query: 478 HIRQHGDLTPWRYASRMSVLLVALLVSVYLTFSPLGVARSGGVTQQYYLWMGLTWALAVL 537 ++ DLT W +A LV L+S+++ SPLG+A + G Q L +G+ L V+ Sbjct: 492 ENKEGVDLTNWEHARVTVASLVLGLISLHVLLSPLGLASTEG---QPLLILGIYAILQVI 548 Query: 538 LLVVLRRR 545 L V R + Sbjct: 549 FLFVFRSK 556 >BH2222 [R] COG4146 Predicted symporter Bha Bacillus halodurans Length = 580 Score = 413 bits (1061), Expect = e-115, Method: Compositional matrix adjust. Identities = 226/520 (43%), Positives = 337/520 (64%), Gaps = 9/520 (1%) Query: 2 SYLFTRRAKDVGARGYFMASGGLNGWFIAGSMMLTNLSVEQLVGLNGDAYAHNLSAMAWE 61 S+ TR + GYF+ L G IA S++LTNLS EQ+VGLNG A+ ++ MAWE Sbjct: 20 SWYKTRGTDLSSSDGYFLGGRSLTGIVIASSLILTNLSTEQVVGLNGQAFGESMVVMAWE 79 Query: 62 CTAAISTVALAMFFLPRYLRGGFSTLPQFLEERFDATTRRVVSAFFVISYMLVVNPSGLY 121 TA I+ + +A FLPRYL+ G +T+P FLE+RFD TR++VS F++ Y V P+ LY Sbjct: 80 VTAPIALILMAFVFLPRYLKLGITTIPDFLEQRFDLRTRQIVSVLFLLGYATVFLPTVLY 139 Query: 122 LGAITFNQVFGVQQAFGASYPVTITGLVWIS-GFIGALYAVFGGLRAVAVSDTINGVGLL 180 GA+ + +F + S P I + I+ G I Y + GGL+A A+SDTING+GL+ Sbjct: 140 SGALVIDSIFSLSSVMDIS-PFMIVLCISIAIGIISCGYVILGGLKACAMSDTINGIGLI 198 Query: 181 IAGLMVPALGLLALGHGDFFAGVHVIATAAPEKLSAIGGPHDSVPFGTVFTGMIFANLFY 240 I GL++P L L LG GDF +GV + +A P KL+AIG SVP+ + TG++F NLFY Sbjct: 199 IGGLLIPILALFVLGRGDFASGVGELVSANPTKLNAIGNDQASVPWAVLLTGLLFNNLFY 258 Query: 241 WCTNQAIIQRTFAAKNLAEGQKGVLLSGLLKLMVPIVMLMPGVIAYHLYAGNPLARPDLA 300 WCTNQ+IIQRT AAKNLAEGQKGVL +G+ K+ +++PG+IAY LY G+ LA D+A Sbjct: 259 WCTNQSIIQRTLAAKNLAEGQKGVLFAGMFKIFGAAFLVLPGIIAYLLY-GDVLANADMA 317 Query: 301 YPQLVADLLPWWAKGFFVAVLFGTVMSHFNAVINSTATLIAFDFYR-VWKPEASDEKMIR 359 YP LV D++P GF AVLFG ++S FN V+NS+ TL D Y+ ++KP A + ++++ Sbjct: 318 YPSLVIDVMPVALSGFLAAVLFGAILSSFNNVLNSSITLFTLDIYKPIFKPNAKEPELVK 377 Query: 360 VGKMASIAVAVISLLIAPLLMFAPDGIYTVMRRFSGFFNIPIIAVVLMGFFNARIDALPA 419 G++ + +A+ +++IAP +++AP G+Y ++ +GF+++PIIA+V++GFF+ + A Sbjct: 378 AGRIFAACLAITAVVIAPFILYAPQGLYYFLQEMNGFYSLPIIAMVIVGFFSKYVPASAP 437 Query: 420 KIVLLLHVIAYTLLIFVFKVDSTYGIHFIHIMGMLFVTEVLLMLVLGQFFRRAQPYQAHI 479 K+++ +HV+ Y V ++F++++ +LF VL+ML++G+ R + Sbjct: 438 KVLVAVHVVLYAGSKVVLG-----EVNFLYVLSVLFPINVLVMLIVGRLKPRETSFVLPT 492 Query: 480 RQHGDLTPWRYASRMSVLLVALLVSVYLTFSPLGVARSGG 519 DLTPW+YA S ++ ++ VY FSPLGVA S G Sbjct: 493 ANKVDLTPWKYAKPFSAFILLTMLGVYTFFSPLGVAESSG 532 >VCA0667 [ER] COG0591 Na+/proline symporter Vch Vibrio cholerae Length = 513 Score = 90.9 bits (224), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 102/371 (27%), Positives = 163/371 (43%), Gaps = 33/371 (8%) Query: 18 FMASGGLNGWFIAG-SMMLTNLSVEQLVGLNGDAYAHNLSAMAWECTAAISTVALAMFFL 76 F G GWF AG S++ T +S +G+ G Y + A+ I +FF+ Sbjct: 34 FSTGGRQFGWFTAGVSILATYISAMTFIGMPGWVYQSGMEALNIHLNYPIVIFFAVVFFI 93 Query: 77 PRYLRGGFSTLPQFLEERFDATTRRVVSAFFVISYMLVVNPSG--LYLGAITFNQVFGVQ 134 P + R GF+++ ++LE RF R + S F++ + SG LY A+ Q+ Sbjct: 94 PVFYRMGFTSIYEYLEHRFGVYARTINSVVFILVQCI---SSGVILYAIALILIQIL--- 147 Query: 135 QAFGASYPVTI-TGLVWISGFIGALYAVFGGLRAVAVSDTINGVGLLIAGLMVPALGLLA 193 P++I +V+I+ F A Y GG+ V +D + +LIAG + A+ +L Sbjct: 148 -------PISIVEAIVYITLF-TACYTYAGGISTVIWTDMLQS-AVLIAGSV--AIFVLL 196 Query: 194 LGHGDFFAGVHVIATAAPEKLSAIGGPHDSVPFGTVFTGMI---FANLFYWCTNQAIIQR 250 L D GVH + + E+L+ I D T++ G++ F ++ + TNQ IIQR Sbjct: 197 LLQVD---GVHGV---SREQLNIINLQFDLGVDTTLWAGVVAVSFLHMSVYGTNQLIIQR 250 Query: 251 TFAAKNLAEGQKGVLLSGLLKLMVPIVMLMPGVIAYHLYAGNPLARPDLAYPQLVADLLP 310 T A + QK +LL G + + GV+ Y + V Sbjct: 251 TLATRCEKTAQKSMLLCGYGAFFIYFFFALLGVLLSIFYQERHFTNSNEVILDFVFHHTN 310 Query: 311 WWAKGFFVAVLFGTVMSHFNAVINSTATLIAFDFY-RVWKPEASDEKMIRVGKMASIAVA 369 W G ++ L MS ++ NS AT+ FD Y R + A D V + S+ A Sbjct: 311 PWVIGLIISALAAAAMSTLDSTYNSMATVATFDLYQRFIRRNAPDHHYQAVARKMSLVAA 370 Query: 370 VISLLIAPLLM 380 L++ P L+ Sbjct: 371 --GLVVIPALL 379 >SA0303 [ER] COG0591 Na+/proline symporter Sau Staphylococcus aureus N315 Length = 510 Score = 86.3 bits (212), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 101/433 (23%), Positives = 182/433 (42%), Gaps = 25/433 (5%) Query: 5 FTRRAKDVGARGYFMASGGLNGWFIAGSMMLTNLSVEQLVGLNGDAYAHNLSAMAWECTA 64 FT+RA +F ASG L W + S+ T LS + A+ + S +A Sbjct: 28 FTKRASQ-STNSFFTASGRLPSWVVGFSIYATTLSAITFMSTPEKAFLTDWSYIAGNIAI 86 Query: 65 AISTVALAMFFLPRYLRGGFSTLPQFLEERFDATTRRVVSAFFVISYMLVVNPSGLYLGA 124 L F++P + + ++ ++LE RF + R + S FV+ Y L +YL Sbjct: 87 VAIIPLLIYFYVPFFKKLKVTSAYEYLEARFGPSIRVIGSLLFVV-YHLGRVAIVIYLPT 145 Query: 125 ITFNQVFGVQQAFGASYPVTITGLVWISGFIGALYAVFGGLRAVAVSDTINGVGLLIAGL 184 + V + P + LV G + LY GG V SD I GV LL L Sbjct: 146 LAITSVSDMN-------PYIVASLV---GLLCILYTFLGGFEGVVWSDFIQGVILLGGAL 195 Query: 185 MVPALGLLALGHGDFFAGVHVIATAAPEKLSA----IGGPHDSVPFGTVFTGMIFANLFY 240 ++ LG++ + G F V A + +SA + ++P +F G IF NL+ Sbjct: 196 VIIILGVMNIKGG--FGTVFADAIEHKKLISADNWKLNTAAAAIPI--IFLGNIFNNLYQ 251 Query: 241 WCTNQAIIQRTFAAKNLAEGQKGVLLSGLLKLMVPIVMLMPGVIAYHLYAGNPLA----R 296 + +Q ++QR A+ +L E K + +G+L L+ + G + Y Y + Sbjct: 252 YTASQDVVQRYQASDSLKETNKSLWTNGILALISAPLFYGMGTMLYSFYTHEAVLPKGFN 311 Query: 297 PDLAYPQLVADLLPWWAKGFFVAVLFGTVMSHFNAVINSTATLIAFDFYRVWKPEASDEK 356 P + +P + G +A +F S ++ +NS + I+ D + + + S+ Sbjct: 312 TSSVVPYFILTEMPPFVAGLLIAAIFAAAQSTISSSLNSISACISIDIKQRFFGKDSERH 371 Query: 357 MIRVGKMASIAVAVISLLIAPLLMFA-PDGIYTVMRRFSGFFNIPIIAVVLMGFFNARID 415 + + I + ++ L+ + + ++ + +G F +P+ V +G F R + Sbjct: 372 EVNFARFIIIIAGIFGFGMSLYLIASNSNDLWDLFLFVTGLFGVPLAGVFAVGIFTKRTN 431 Query: 416 ALPAKIVLLLHVI 428 L+L +I Sbjct: 432 TFGVICGLILGII 444 >SP1328 [ER] COG0591 Na+/proline symporter Spn Streptococcus pneumoniae TIGR4 Length = 513 Score = 85.1 bits (209), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 99/400 (24%), Positives = 175/400 (43%), Gaps = 31/400 (7%) Query: 10 KDVGARGYFMASGGLNGWFIAGSMMLTNLSVEQLVGLNGDAYAHNLSAMAWECTAAISTV 69 K++ + +F G + + + S+ T LS +GL G +YA S + W + V Sbjct: 31 KEMKGKEFFKGDGSVPWYVTSVSIFATMLSPISFLGLAGSSYAG--SWILWFAQLGM-VV 87 Query: 70 ALAM---FFLPRYLRGGFSTLPQFLEERFDATTRRVVSAFFVISYMLVVNPSGLYLGAIT 126 A+ + F LP + R T +L++RF++ R++SA I Y L +YL + Sbjct: 88 AIPLTIRFILPIFARIDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAG 147 Query: 127 FNQVFGVQQAFGASYPVTITGLVWISGFIGALYAVFGGLRAVAVSDTINGVGLLIAGLMV 186 + + G+ I L+ + G + +Y+ GGL++V +D I GV +LI+G+++ Sbjct: 148 LSVLTGID----------INILIILMGVVAIVYSYTGGLKSVLWTDFIQGV-ILISGVVL 196 Query: 187 PALGLLALGHGDFFAGVHVIAT----AAPEKLSAIGGPHDSVPFGTVFTGMIFANLFYWC 242 L+A G F A +A AA EKL +S+ + G F L + Sbjct: 197 ALFVLIANIKGGFGAVAETLANGKFLAANEKLFDPNLLSNSIFL--IVMGSGFTILSSYA 254 Query: 243 TNQAIIQRTFAAKNLAEGQKGVLLSGLLKLMVPIVMLMPGVIAYHLYAGNPLARPDLAYP 302 ++Q ++QR +N+ + K + +G+L L V + G Y Y P Sbjct: 255 SSQDLVQRFTTTQNIKKLNKMLFTNGVLSLATATVFYLIGTGLYVFYQVQNADSAASNIP 314 Query: 303 Q------LVADLLPWWAKGFFVAVLFGTVMSHFNAVINSTATLIAFDFYRVWKPEASDEK 356 Q +A LP G +A ++ S + +NS AT D V SD + Sbjct: 315 QDQIFMYFIAYQLPVGITGLILAAIYAASQSTISTGLNSVATSWTLDIQDVISKNMSDNR 374 Query: 357 MIRVGKMASIAVAVISLLIAPLLMFAPDGIYTVMRRFSGF 396 ++ + S+AV + S+ ++ ++ A I + F+ F Sbjct: 375 RTKIAQFVSLAVGLFSIGVS--IVMAHSDIKSAYEWFNSF 412 >sll1087 [ER] COG0591 Na+/proline symporter Syn Synechocystis Length = 512 Score = 80.5 bits (197), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 93/367 (25%), Positives = 161/367 (43%), Gaps = 50/367 (13%) Query: 75 FLPRYLRGGFSTLPQFLEERFDATTRRVVSAFFVISYMLVVNPSG-LYLGAITFNQVFGV 133 FLP ++R +T ++LE RFDA TR + S F++ ++ G LY A+ + + G+ Sbjct: 91 FLPFFVRLNLTTAYEYLERRFDAKTRSLGSLCFLL--FVIARLGGLLYAAALVLSVLTGI 148 Query: 134 QQAFGASYPVTITGLVWISGFIGALYAVFGGLRAVAVSDTINGVGLLIAGLMVPALGLLA 193 T T ++ + G + +Y V GG+ AV +D + G++ Sbjct: 149 S---------TNTAILMV-GVVSIIYTVAGGITAVVWTDVLQ-------------FGMIF 185 Query: 194 LGHGDFFAGVHVIATAAP---EKLSAIGGPH----------DSVPFGTVFTGMIFANLFY 240 +G G AG+ TA P +L I G + D ++ T +I + Sbjct: 186 VGLG---AGIWAAVTAVPGGFGELWRIAGENGKLVVFNFDWDPASIRSLPTALIAYGILA 242 Query: 241 WC---TNQAIIQRTFAAKNLAEGQKGVLLSGLLKLMVPIVMLMPGVIA---YHLYAGNP- 293 + TNQ +QR + + +K + L ++ L+ GV+ Y L G P Sbjct: 243 FAVAGTNQQSVQRYVSCADEQSARKAIFLGWFSGVLGVGATLLLGVLLFSFYQLQGGLPG 302 Query: 294 LARPDLAYPQLVADLLPWWAKGFFVAVLFGTVMSHFNAVINSTATLIAFDFY-RVWKPEA 352 +PD + + +P A GF VA +F MS ++ ++S AT + DFY R +A Sbjct: 303 NIKPDEILSYFIVNQVPPGASGFLVAAIFAAAMSSIDSALHSLATCMTVDFYDRYINIQA 362 Query: 353 SDEKMIRVGKMASIAVAVISLLIAPLLMFAPDGIYTVMRRFSGFFNIPIIAVVLMGFFNA 412 S+ + +RV + I V+++ A + + ++ F P++ + LMG Sbjct: 363 SEMRSVRVAQGLIIVWGVVAIFSAIYAASTGQDLLEFLVSYTTMFLGPLLGIFLMGVLFP 422 Query: 413 RIDALPA 419 RI+AL A Sbjct: 423 RINALGA 429 >BH2706 [ER] COG0591 Na+/proline symporter Bha Bacillus halodurans Length = 507 Score = 76.3 bits (186), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 89/386 (23%), Positives = 168/386 (43%), Gaps = 37/386 (9%) Query: 6 TRRAKDVGARGYFMASGGLNGWFIAGSMMLTNLSVEQLVGLNGDAYAHNLSAMAWECTAA 65 + + VG +F+A LN W +A S + + S ++G+ G AYA L A+ W Sbjct: 26 SSKKSSVGMTDFFIAGRNLNKWTVALSAVSSGRSAWLVLGVTGTAYATGLDAV-WAVAGY 84 Query: 66 ISTVALAMFFLPRYLRG-----GFSTLPQFLEERFDATTR--RVVSAFFVISYMLVVNPS 118 I+ F++ R R G T+P LE RF+ T R SAF ++ +M+ S Sbjct: 85 ITVEVFLFFYVARRFRAYSEQTGSITIPDILETRFNDKTHILRGGSAFIIMFFMIAYVAS 144 Query: 119 GLYLGAITFNQVFGVQQAFGASYPVTITGLVWISGFIGALYAVFGGLRAVAVSDTINGVG 178 L G F GV + G +W++ I Y + GG AV+ +D + Sbjct: 145 QLVAGGGAFATSMGVSSSTG----------MWVTAVILLAYTMLGGFHAVSKTDVVQAGF 194 Query: 179 LLIAGLMVPALGLLALGHGDFFAGVHVIATAAPEKLSAIGGPHDSVPFGTVFTGMI--FA 236 + ++ +++P + ++ LG D + V+ T GG S PF F +I Sbjct: 195 MFVSLVILPVVAIIGLGGFDPL--LQVMHTE--------GGGFTS-PFAFGFGAVIGLLG 243 Query: 237 NLFYWCTNQAIIQRTFAAKNLAEGQKGVLLSGLLKLMVPIVMLMPGVIAYHLYAGN---P 293 F N I+ R + KN+ E ++ L+S + +++ +M G+ + P Sbjct: 244 IGFGSPGNPHILVRYMSLKNVKEMRQAALISSVWNVLMGWGAVMIGLAGRAYFPDVSLLP 303 Query: 294 LARPDLAYPQLVADLLPWWAKGFFVAVLFGTVMSHFNAVINSTATLIAFDFYRVW---KP 350 + + L +++L GF + + +MS ++ + ++ D Y+ Sbjct: 304 NGDQEQVFLMLGSEILHPLFFGFLLVAVLAAIMSSADSQLLVGSSAFVRDIYQKMFRRNR 363 Query: 351 EASDEKMIRVGKMASIAVAVISLLIA 376 + S +K++R+ ++ ++ +SL++A Sbjct: 364 KLSQKKLVRLSRLTTVVFMGLSLILA 389