BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0238.p (301 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA0123 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 201 2e-51 VC1955 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae 142 1e-33 RSp0910 [K] COG0583 Transcriptional regulator Rso Ralstonia sola... 136 7e-32 SMa1602 [K] COG0583 Transcriptional regulator Sme Sinorhizobium ... 135 1e-31 YPO3683 [K] COG0583 Transcriptional regulator Ype Yersinia pestis 135 1e-31 AGl567 [K] COG0583 Transcriptional regulator Atu Agrobacterium t... 135 2e-31 VCA0635 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae 134 2e-31 STM3367 [K] COG0583 Transcriptional regulator Sty Salmonella typ... 134 2e-31 yhcS [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 134 3e-31 ECs4116 [K] COG0583 Transcriptional regulator Ecs Escherichia co... 134 3e-31 >PA0123 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 302 Score = 201 bits (511), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 108/287 (37%), Positives = 166/287 (57%), Gaps = 2/287 (0%) Query: 1 MATFARVVELGAFSRAAKALGLTTSSVSQHVRALELSLQATLLNRSTRKLSLTEAGTLFY 60 MA FA VV+ G+ + AA++LG+T S+VSQ +R LE Q TLL+R+TR+L+LTEAG FY Sbjct: 7 MAIFATVVDKGSMAAAAQSLGMTPSAVSQQIRKLESRAQVTLLHRTTRRLTLTEAGEAFY 66 Query: 61 KHCAHIVTAASEAEQSIAVLNNEMVGEVRIAVSSFMSTKYLIPALHDFIRHNPKVRLRLE 120 + CA ++ A EAE+ + + VGE+R+A S + AL + ++ ++RL+L Sbjct: 67 RSCAQMLAIAEEAERRLGEWRDAPVGELRLAAPVGFSGTLITQALKPLLENHRQLRLQLF 126 Query: 121 VADNNVDLIEQRIDLALRAGRNRQPGDI--FLGRFSDVLCASPSYLAVRPPIHSPVDLLH 178 D +DL+ +RIDLA+R G + LG +S VLCA+P+YL R PI+ P L Sbjct: 127 FQDERIDLVAERIDLAIRVGNLADSSLVARHLGDWSSVLCAAPAYLRQRAPINRPEQLTE 186 Query: 179 HDFLLFNPHGEPCFLEFSNAASGTVRVRLQPRISANHARSLRYLALDGHGITRLLECKIE 238 D++ N L S ++RL+PR++AN ++R LDG G++ ++ Sbjct: 187 VDWISLNTSNHLNHLTLSGPGGEVCKLRLEPRVAANGMLAVRQFTLDGLGVSYQPLPEVR 246 Query: 239 DDLRTGRLVQVLPDWTLGGFDVYVTVRHRDNMPLKVRQCLEHIQHYF 285 D L GRL Q+LP+W + G +Y R+ P KV+ +E ++ F Sbjct: 247 DALNDGRLQQLLPEWRIPGLGIYAVTPRREAQPAKVKVAIEALRRAF 293 >VC1955 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae Length = 315 Score = 142 bits (358), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 89/289 (30%), Positives = 156/289 (53%), Gaps = 9/289 (3%) Query: 1 MATFARVVELGAFSRAAKALGLTTSSVSQHVRALELSLQATLLNRSTRKLSLTEAGTLFY 60 MA FA +++ +F+ AA ALG++ S VS+ + ALE SL L+ R+TR +LT+AG LFY Sbjct: 9 MALFAVLIQHQSFTAAAHALGVSVSHVSKQLAALEASLGVKLVQRTTRSFTLTDAGNLFY 68 Query: 61 KHCAHIVTAASEAEQSIAVLNNEMVGEVRIAVSSFMSTKYLIPALHDFIRHNPKVRLRLE 120 C ++T + A+ + +E+VG +R+ +S T +++PAL + P++ + + Sbjct: 69 AQCRELLTIVTNAQSEMEDQRDEVVGLIRLGLSQSFGTLHVLPALEQLRQQYPELNVEVH 128 Query: 121 VADNNVDLIEQRIDLALRAGRNRQ-PGDIFLGRFSD---VLCASPSYLAVRPPIHSPVDL 176 + D+ VD++++ +DL + + N Q P R +D V+ ASP YL P+ L Sbjct: 129 LFDHKVDMLKEGLDLWITS--NEQLPEGYVAQRIADCRFVVAASPDYLLRYGSPTEPMAL 186 Query: 177 LHHDFLLFNPHGEPCFLEFSNAASG-TVRVRLQPRISANHARSLRYLALDGHGITRLLEC 235 + H+ L++ E + +S + G +++ S + A ++R A+ G GI L Sbjct: 187 MEHNCLIYRS-WERDYTRWSFSRDGHNQTIKVAGNYSVDLAEAVRDAAVAGWGIAYLATY 245 Query: 236 KIEDDLRTGRLVQVLPDWTLG-GFDVYVTVRHRDNMPLKVRQCLEHIQH 283 + D+ RTG+L+Q+LP+W+ Y R +MP K +E I+ Sbjct: 246 LLRDEFRTGQLIQLLPEWSANQQMPFYAVYPSRQHMPKKTSAVIEFIKQ 294 >RSp0910 [K] COG0583 Transcriptional regulator Rso Ralstonia solanacearum Length = 309 Score = 136 bits (342), Expect = 7e-32, Method: Compositional matrix adjust. Identities = 89/257 (34%), Positives = 135/257 (52%), Gaps = 5/257 (1%) Query: 1 MATFARVVELGAFSRAAKALGLTTSSVSQHVRALELSLQATLLNRSTRKLSLTEAGTLFY 60 ++ F VVE G F+ AA+ LGL SS+++ + ALE SL L+NRSTR ++LTEAG +Y Sbjct: 7 LSAFVAVVEHGGFAPAARRLGLAPSSLTRQLNALEASLGTRLMNRSTRSVTLTEAGAQYY 66 Query: 61 KHCAHIVTAASEAEQSIAVLNNEMVGEVRIAVSSFMSTKYLIPALHDFIRHNPKVRLRLE 120 I+ A+++++ L G +R+ + ++ PA+ F+R P +RL + Sbjct: 67 DDARRILEELDSADRTVSELAGPPSGLLRVTMPVAFGRLHVAPAIPAFLRRFPGMRLDIR 126 Query: 121 VADNNVDLIEQRIDLALRAGRNRQPGDIF--LGRFSDVLCASPSYLAVRPPIHSPVDLLH 178 + D V+L+E RID+A+R G P + L V+CASP YL P DL H Sbjct: 127 LTDAMVNLVEDRIDVAIRLGALTAPNLVARKLAPHRRVICASPDYLGEHGTPAQPRDLAH 186 Query: 179 HDFLLFNP-HGEPCFLEFSNAASGTVRVRLQPRISANHARSLRYLALDGHGITRLLECKI 237 H+ LLF+ G+ + + V V + AN + LR A+ G G+ + + Sbjct: 187 HNCLLFDYLTGDSTWTLTRDGKREKVPV--SGNLRANGSELLREAAMGGAGMLLMPTWLV 244 Query: 238 EDDLRTGRLVQVLPDWT 254 DD+ GRLV VL WT Sbjct: 245 GDDIAAGRLVPVLEPWT 261 >SMa1602 [K] COG0583 Transcriptional regulator Sme Sinorhizobium meliloti Length = 302 Score = 135 bits (340), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 87/285 (30%), Positives = 149/285 (52%), Gaps = 11/285 (3%) Query: 1 MATFARVVELGAFSRAAKALGLTTSSVSQHVRALELSLQATLLNRSTRKLSLTEAGTLFY 60 MA F V +F +AA+ALG+ S++S+ V LE ++ LL+R+TRK+ LTEAG L+Y Sbjct: 18 MALFVEVARARSFRKAAEALGMPNSTLSRRVSELEKAIGLRLLHRTTRKIELTEAGQLYY 77 Query: 61 KHCAHIVTAASEAEQSIAVLNNEMVGEVRIAVSSFMSTKYLIPALHDFIRHNPKVRLRLE 120 + IV A A + + + N+ G +R+++ ++T YL P + +F RH P + + Sbjct: 78 ERSKRIVDEARLAHEQLGAMLNQPSGVLRVSLPVNLATFYLTPIIGEFARHYPGITFEFD 137 Query: 121 VADNNVDLIEQRIDLALRAGRNRQPGDI--FLGRFSDVLCASPSYLAVRPPIHSPVDLLH 178 + VDL+ + D+A+R G+ G I +GR S L ASP Y+ +P +L Sbjct: 138 LTPRRVDLVAEPFDVAIRIGKLEDSGLITRLIGRHSRHLYASPGYIEASGEPATPAELAE 197 Query: 179 HDF--LLFNPHGEPCFLEFSNAASGTVRVRLQPRISANHARSLRYLALDGHGITRLLECK 236 H+ +L +P + + V V ++ R + N +R LA++ GI L E Sbjct: 198 HECIGMLRSP------IWSLHQGINKVDVAVRGRFTLNSVGMIRALAVNHQGIALLPEKI 251 Query: 237 IEDDLRTGRLVQVLPDWTLGGFDVYVTVRHRDNMPLKVRQCLEHI 281 + +D+ GRL ++LP+W ++ R +P K ++ +E + Sbjct: 252 VAEDVAFGRLRRILPEWQGSAVSIFAVTETR-LIPAKTQRFIEFL 295 >YPO3683 [K] COG0583 Transcriptional regulator Ype Yersinia pestis Length = 303 Score = 135 bits (339), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 87/291 (29%), Positives = 144/291 (49%), Gaps = 5/291 (1%) Query: 1 MATFARVVELGAFSRAAKALGLTTSSVSQHVRALELSLQATLLNRSTRKLSLTEAGTLFY 60 M+ FA+VVE G+F+ AA+ L + SS+SQ V LE L LLNRSTR++ LTEAG ++Y Sbjct: 7 MSVFAKVVECGSFTAAARRLENSVSSISQTVSKLENELNVKLLNRSTRRIGLTEAGRIYY 66 Query: 61 KHCAHIVTAASEAEQSIAVLNNEMVGEVRIAVSSFMSTKYLIPALHDFIRHNPKVRLRLE 120 + C ++ + + + NN G +RI SS M+ L D ++ P + + L Sbjct: 67 QGCRRMLQEVQQVHEQLYAFNNTPTGTLRIGCSSTMAQNVLATMTADMLKAYPGLSVNLV 126 Query: 121 VADNNVDLIEQRIDLALRAGRNRQPGDIF---LGRFSDVLCASPSYLAVRPPIHSPVDLL 177 DLI +D+ +R G + G +F LG V+CA+ SYL+ P D+ Sbjct: 127 AGIPAPDLIADGLDVVIRVGALQNSG-LFSRRLGAMPMVVCAAKSYLSQYGTPAKPSDMA 185 Query: 178 HHDFLLFNPHGEPCFLEFSNAASGTVRVRLQPRISANHARSLRYLALDGHGITRLLECKI 237 + +L +N + F E T ++ Q R N ++++ G GI + Sbjct: 186 NFSWLEYNVRPDSNF-ELIAPEGITTQISPQGRFVTNDSQTMIRWLKAGAGIAYTPLMWV 244 Query: 238 EDDLRTGRLVQVLPDWTLGGFDVYVTVRHRDNMPLKVRQCLEHIQHYFEVV 288 ++++ G + + + VY +D MPLKV+ C++++ YF+ V Sbjct: 245 IEEIKRGEVEILFKHYHSDPRPVYALYTEKDKMPLKVQVCIDYLTEYFKRV 295 >AGl567 [K] COG0583 Transcriptional regulator Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 301 Score = 135 bits (339), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 103/295 (34%), Positives = 146/295 (49%), Gaps = 14/295 (4%) Query: 1 MATFARVVELGAFSRAAKALGLTTSSVSQHVRALELSLQATLLNRSTRKLSLTEAGTLFY 60 M F RVVELG FSRAA A +T S+VS+ + LE L A LLNRSTR+L +T G FY Sbjct: 12 MEIFVRVVELGGFSRAAAAANMTPSAVSKLIARLESRLGARLLNRSTRQLQITPEGCAFY 71 Query: 61 KHCAHIVTAASEAEQSIAVLNNEMVGEVRIAVSSFMSTKYLIPALHDFIRHNPKVRLRLE 120 + I+ EAE++ A +G VRI S+ +T L P L F+ +P++ L + Sbjct: 72 ERATRILADLEEAERA-AGERERPIGRVRINTSASYATHILAPILPRFLALHPEITLDIV 130 Query: 121 VADNNVDLIEQRIDLALRAGRNRQPGDIF--LGRFSDVLCASPSYLAVRPPIHSPVDLLH 178 D VDL+ +R+D+A+RAG + + LG V+ A+P YL + DL Sbjct: 131 QTDLVVDLLAERMDVAVRAGPLKSSSLVARKLGETRMVIAAAPDYLKRCGVPQTISDLEG 190 Query: 179 HDFLLF----NPHGEPCFLEFSNAASGTVRVRLQPRISANHARSLRYLALDGHGITRLLE 234 H+ L + G P TV + R+ + LR LAL G G+ RL Sbjct: 191 HNCLALGYARSIDGWPL-----QDGGKTVVIPATGRVQVSDGEGLRRLALAGVGLVRLAA 245 Query: 235 CKIEDDLRTGRLVQVLPDWTLGGFDVY--VTVRHRDNMPLKVRQCLEHIQHYFEV 287 I +D+ GRLV VL G + + V V R +P ++R L+ + Y V Sbjct: 246 FTIREDIAAGRLVSVLDHLDTGETETFHAVYVGQRGPLPSRIRALLDFLGEYGRV 300 >VCA0635 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae Length = 313 Score = 134 bits (338), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 91/289 (31%), Positives = 140/289 (48%), Gaps = 17/289 (5%) Query: 4 FARVVELGAFSRAAKALGLTTSSVSQHVRALELSLQATLLNRSTRKLSLTEAGTLFYKHC 63 F G+FS+AA +L LTT++VS +R LE +Q L RSTR + LT G +F Sbjct: 10 FVETARQGSFSKAANSLSLTTAAVSAAIRRLEEQVQFPLFVRSTRHIRLTHEGEIFLAKT 69 Query: 64 AHIVTAASEAEQSIAVLNNEMVGEVRIAVSSFMSTKYLIPALHDFIRHNPKVRLRLEVAD 123 + E IA ++ G++ I+ S + L+ + +FI +P V ++L+++D Sbjct: 70 QTALATLQEGLDQIACARGQLAGQLHISAPSDLGRNLLLDWIDEFIALHPNVTVKLDLSD 129 Query: 124 NNVDLIEQRIDLALRAGRNRQPGD------IFLGRFSDVLCASPSYLAVRPPIHSPVDLL 177 D+ +D+A+R G QP D + VLCASP YLA PPI P DL Sbjct: 130 RLTDMYANPVDIAIRYG---QPADSNLVAMLLCDSNERVLCASPEYLAAHPPILHPDDLQ 186 Query: 178 HHDFLLF----NPHGEPCFLEFSNAASGTVRVRLQPRISANHARSLRYLALDGHGITRLL 233 HH+ L F H + ++ N + +V V+ P + N + LA+ G GI Sbjct: 187 HHNCLCFMLADTLHNK--WILSRNGETHSVVVQGNP--ACNDGEVVHRLAVKGKGIANKS 242 Query: 234 ECKIEDDLRTGRLVQVLPDWTLGGFDVYVTVRHRDNMPLKVRQCLEHIQ 282 I D+ GRLV++LP+W G +Y+ R + +R E I+ Sbjct: 243 LMDISQDIIDGRLVRILPEWESGPVPIYMVCADRRLITPTIRAFQEFIR 291 >STM3367 [K] COG0583 Transcriptional regulator Sty Salmonella typhimurium LT2 Length = 309 Score = 134 bits (338), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 92/290 (31%), Positives = 139/290 (47%), Gaps = 9/290 (3%) Query: 1 MATFARVVELGAFSRAAKALGLTTSSVSQHVRALELSLQATLLNRSTRKLSLTEAGTLFY 60 M+ FA+VVE G+F+ AA+ L ++ SS+SQ V LE LQ LLNRSTR + LTEAG ++Y Sbjct: 7 MSVFAKVVEFGSFTAAARQLQMSVSSISQTVAKLEDELQVKLLNRSTRSIGLTEAGKIYY 66 Query: 61 KHCAHIVTAASEAEQSIAVLNNEMVGEVRIAVSSFMSTKYLIPALHDFIRHNPKVRLRLE 120 + C ++ + + + NN +G +RI SS M+ L ++ P + + L Sbjct: 67 QGCRRMLHEVQDVHEQLYAFNNTPIGTLRIGCSSTMAQNVLAGLTAKLLKEYPGLAVNLV 126 Query: 121 VADNNVDLIEQRIDLALRAGRNRQPGDIF---LGRFSDVLCASPSYLAVRPPIHSPVDLL 177 DLI +D+ +R G Q +F LG V+CA+ YLA P DL Sbjct: 127 TGIPAPDLIADGLDVVIRVG-ALQDSSLFSRRLGAMPMVVCAAKPYLAQYGVPEKPADLS 185 Query: 178 HHDFLLFNPHGEPCFLEFSNAASGTVRVRLQP--RISANHARSLRYLALDGHGITRLLEC 235 H +L ++ + EF A + RL P R N +L G GI + Sbjct: 186 SHSWLEYSVRPDN---EFELIAPEGISTRLIPQGRFVTNDPMTLVRWLTAGTGIAYVPLM 242 Query: 236 KIEDDLRTGRLVQVLPDWTLGGFDVYVTVRHRDNMPLKVRQCLEHIQHYF 285 + D++ G L +LP + VY +D +PLKV+ + + YF Sbjct: 243 WVIDEINRGDLEILLPRYQSDPRPVYALYTEKDKLPLKVQVVINALTDYF 292 >yhcS [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 Length = 309 Score = 134 bits (336), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 91/290 (31%), Positives = 139/290 (47%), Gaps = 9/290 (3%) Query: 1 MATFARVVELGAFSRAAKALGLTTSSVSQHVRALELSLQATLLNRSTRKLSLTEAGTLFY 60 M+ FA+VVE G+F+ AA+ L ++ SS+SQ V LE LQ LLNRSTR + LTEAG ++Y Sbjct: 7 MSVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDELQVKLLNRSTRSIGLTEAGRIYY 66 Query: 61 KHCAHIVTAASEAEQSIAVLNNEMVGEVRIAVSSFMSTKYLIPALHDFIRHNPKVRLRLE 120 + C ++ + + + NN +G +RI SS M+ L ++ P + + L Sbjct: 67 QGCRRMLHEVQDVHEQLYAFNNTPIGTLRIGCSSTMAQNVLAGLTAKMLKEYPGLSVNLV 126 Query: 121 VADNNVDLIEQRIDLALRAGRNRQPGDIF---LGRFSDVLCASPSYLAVRPPIHSPVDLL 177 DLI +D+ +R G Q +F LG V+CA+ SYL P DL Sbjct: 127 TGIPAPDLIADGLDVVIRVG-ALQDSSLFSRRLGAMPMVVCAAKSYLTQYGIPEKPADLS 185 Query: 178 HHDFLLFNPHGEPCFLEFSNAASGTVRVRLQP--RISANHARSLRYLALDGHGITRLLEC 235 H +L ++ + EF A + RL P R N +L G GI + Sbjct: 186 SHSWLEYSVRPDN---EFELIAPEGISTRLIPQGRFVTNDPMTLVRWLTAGAGIAYVPLM 242 Query: 236 KIEDDLRTGRLVQVLPDWTLGGFDVYVTVRHRDNMPLKVRQCLEHIQHYF 285 + +++ G L +LP + VY +D +PLKV+ + + YF Sbjct: 243 WVINEINRGELEILLPRYQSDPRPVYALYTEKDKLPLKVQVVINSLTDYF 292 >ECs4116 [K] COG0583 Transcriptional regulator Ecs Escherichia coli O157:H7 Length = 309 Score = 134 bits (336), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 91/290 (31%), Positives = 139/290 (47%), Gaps = 9/290 (3%) Query: 1 MATFARVVELGAFSRAAKALGLTTSSVSQHVRALELSLQATLLNRSTRKLSLTEAGTLFY 60 M+ FA+VVE G+F+ AA+ L ++ SS+SQ V LE LQ LLNRSTR + LTEAG ++Y Sbjct: 7 MSVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDELQVKLLNRSTRSIGLTEAGRIYY 66 Query: 61 KHCAHIVTAASEAEQSIAVLNNEMVGEVRIAVSSFMSTKYLIPALHDFIRHNPKVRLRLE 120 + C ++ + + + NN +G +RI SS M+ L ++ P + + L Sbjct: 67 QGCRRMLHEVQDVHEQLYAFNNTPIGTLRIGCSSTMAQNVLAGLTAKMLKEYPGLSVNLV 126 Query: 121 VADNNVDLIEQRIDLALRAGRNRQPGDIF---LGRFSDVLCASPSYLAVRPPIHSPVDLL 177 DLI +D+ +R G Q +F LG V+CA+ SYL P DL Sbjct: 127 TGIPAPDLIADGLDVVIRVG-ALQDSSLFSRRLGAMPMVVCAAKSYLTQYGIPEKPADLS 185 Query: 178 HHDFLLFNPHGEPCFLEFSNAASGTVRVRLQP--RISANHARSLRYLALDGHGITRLLEC 235 H +L ++ + EF A + RL P R N +L G GI + Sbjct: 186 SHSWLEYSVRPDN---EFELIAPEGISTRLIPQGRFVTNDPMTLVRWLTAGAGIAYVPLM 242 Query: 236 KIEDDLRTGRLVQVLPDWTLGGFDVYVTVRHRDNMPLKVRQCLEHIQHYF 285 + +++ G L +LP + VY +D +PLKV+ + + YF Sbjct: 243 WVINEINRGELEILLPRYQSDPRPVYALYTEKDKLPLKVQVVINSLTDYF 292