BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0202.p (204 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA1644 [R] COG1853 Conserved protein/domain typically associated... 208 7e-54 aq_928 [R] COG1853 Conserved protein/domain typically associated... 130 1e-30 SA2452 [R] COG1853 Conserved protein/domain typically associated... 130 3e-30 SMa1653 [R] COG1853 Conserved protein/domain typically associate... 126 4e-29 RSc1820 [R] COG1853 Conserved protein/domain typically associate... 116 3e-26 AGl355 [R] COG1853 Conserved protein/domain typically associated... 115 5e-26 AGpA605 [R] COG1853 Conserved protein/domain typically associate... 115 6e-26 SMc02426 [R] COG1853 Conserved protein/domain typically associat... 112 7e-25 BH2278 [R] COG1853 Conserved protein/domain typically associated... 105 5e-23 DR2585 [R] COG1853 Conserved protein/domain typically associated... 105 7e-23 >PA1644 [R] COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family Pae Pseudomonas aeruginosa Length = 202 Score = 208 bits (529), Expect = 7e-54, Method: Compositional matrix adjust. Identities = 97/204 (47%), Positives = 138/204 (67%), Gaps = 2/204 (0%) Query: 1 MLIDFAELKPVEAYEWMSSLIVPRPIAWVSTLDAQGRANLAPFSFFQMVTGKPPTLLICP 60 M +DF + P EAY W++S + PRPIAWVSTL A+G +NLAPFSFFQ+++ +PPTL++ Sbjct: 1 MQLDFTTIAPAEAYRWLASTVTPRPIAWVSTLSAEGASNLAPFSFFQVISDEPPTLMVNV 60 Query: 61 LLQRGGKLKDTVLNIDERGEFVVNLATPAQAAQLNETSFPFEAGVSEFEACGVTAAPSQR 120 L+ G LKDT+ N+ G+ V++L AQA +N TS GVSE E G+ S R Sbjct: 61 SLRDDGSLKDTLRNVQATGQLVIHLVGAAQAETMNATSAWLPHGVSEIETVGIPTVSSVR 120 Query: 121 VAPPRVAAAAASFECKLAMLEPYPRHAPSCHLVFGEVLVAHVQDDLLDADGKLDPGKVDL 180 VAPPR+AAAA +FEC++A ++PYP P+CHL+F VL+AHV D +L + +D ++DL Sbjct: 121 VAPPRIAAAAVAFECEVAEIKPYPAENPNCHLIFARVLLAHVDDAVLADERHVDSARLDL 180 Query: 181 LFRMGGEWYGRSVNAANFTLPRPR 204 + R+GG Y + + F++ RPR Sbjct: 181 VGRLGGSHYSHTRD--TFSMIRPR 202 >aq_928 [R] COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family Aae Aquifex aeolicus Length = 196 Score = 130 bits (328), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 69/179 (38%), Positives = 102/179 (56%), Gaps = 4/179 (2%) Query: 14 YEWMSSLIVPRPIAWVSTLDAQGRANLAPFSFFQMVTGKPPTLLICPLLQRGGKLKDTVL 73 Y+ + L+VPRPI WVST+ G N+APFSFF +V +PP L+I + LKDTV Sbjct: 14 YKLVLGLVVPRPIGWVSTISKDGILNIAPFSFFNVVNDEPPVLMISVSNRDDNTLKDTVK 73 Query: 74 NIDERGEFVVNLATPAQAAQLNETSFPFEAGVSEFEACGVTAAPSQRVAPPRVAAAAASF 133 N+ + EFVVN+ + ++ T F V+EFE G+T S+ V PR+ A SF Sbjct: 74 NVLDTKEFVVNMVSEEVFEKMLITGEEFPPEVNEFEKAGLTPETSKFVKAPRIKEAKVSF 133 Query: 134 ECKLAMLEPYPRHAPSCHLVFGEVLVAHVQDDLLDADGKLDPGKVDLLFRMGGEWYGRS 192 ECKL P H++FGE L+ V+D +LD + ++ K + R+GG++Y ++ Sbjct: 134 ECKLYKYVP----VYDMHVIFGEALLIKVEDTILDENLNVNYEKYRPIGRLGGKYYVKA 188 >SA2452 [R] COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family Sau Staphylococcus aureus N315 Length = 203 Score = 130 bits (326), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 70/201 (34%), Positives = 104/201 (51%), Gaps = 5/201 (2%) Query: 4 DFAELKPVEAYEWMSSLIVPRPIAWVSTLDAQGRANLAPFSFFQMVTGKPPTLLICPLLQ 63 D L E Y+ + I+PRPIA+V+TL+ N APFSFF +V PP + I +Q Sbjct: 5 DAQSLTARENYKLLIGSIIPRPIAFVTTLNQDASVNAAPFSFFNIVNNHPPMVAIA--VQ 62 Query: 64 R-GGKLKDTVLNIDERGEFVVNLATPAQAAQLNETSFPFEAGVSEFEACGVTAAPSQRVA 122 R GGK KDT LNI+ G+FVV++ +NET+ P G SE G++ S + Sbjct: 63 RAGGKRKDTALNIERTGDFVVHITDEDNVQDINETAAPLAYGDSELSRTGLSLLTSTTIK 122 Query: 123 PPRVAAAAASFECKLAMLEPYPRHAPSCHLVFGEVLVAHVQDDLLDADGKLDPGKVDLLF 182 P + A FECKL+ + L+ GE++ H+ D + + D K++P + + Sbjct: 123 TPGIKDAKMRFECKLSQMILLGDVLDGADLIIGEIVTYHIDDSIYEGDFKINPHALQAVS 182 Query: 183 RMGGEWYGRSVNAANFTLPRP 203 R+ G Y + FT+ RP Sbjct: 183 RLAGNDYAKL--GGIFTIKRP 201 >SMa1653 [R] COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family Sme Sinorhizobium meliloti Length = 241 Score = 126 bits (316), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 67/172 (38%), Positives = 100/172 (58%), Gaps = 4/172 (2%) Query: 1 MLIDFAELKPVEAYEWMSSLIVPRPIAWVSTLDAQGRANLAPFSFFQMVTGKPPTLLICP 60 M DFAEL + Y + + + PRPIA V+T+D QG N AP SFF + + PP L++ Sbjct: 1 MEFDFAELPEKDRYRLLCAFVGPRPIALVTTIDEQGCKNAAPMSFFNVFSHDPPLLILGM 60 Query: 61 LLQRGGKLKDTVLNIDERGEFVVNLATPAQAAQLNETSFPFEAGVSEFEACGVTAAPSQR 120 + G KDTV NI GEFVV++ A A ++ T F + V E + G+T+ S + Sbjct: 61 QTRPDGNSKDTVANIRRSGEFVVHMVDMAIAKEMIITGINFPSDVDEIQVSGLTSVSSVK 120 Query: 121 VAPPRVAAAAASFECKLAMLEPYPRHAPSCHLVFGEVLVAHVQDDLLDADGK 172 VAPPR+ + + EC+++ + Y R + +V GEVL +V+D+ LDA G+ Sbjct: 121 VAPPRIQESPCAMECRVSQILNYGRRS----IVIGEVLQMYVRDECLDASGR 168 >RSc1820 [R] COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family Rso Ralstonia solanacearum Length = 207 Score = 116 bits (291), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 76/195 (38%), Positives = 105/195 (53%), Gaps = 10/195 (5%) Query: 14 YEWMSSLIVPRPIAWVSTLDAQGRANLAPFSFFQMVTGKPPTLLICPLLQRGGKLKDTVL 73 ++ + +++ PRPI W+ST DA+GR NLAP+SFF + KPP + + GK KD+V Sbjct: 19 HDPIPAILGPRPIGWISTRDAEGRLNLAPYSFFNIFNYKPPLVAFSSV----GK-KDSVR 73 Query: 74 NIDERGEFVVNLATPAQAAQLNETSFPFEAGVSEFEACGVTAAPSQRVAPPRVAAAAASF 133 N + GEFV NLAT A Q+N+TS G+ EF G+T A VA PRVA + S Sbjct: 74 NAEATGEFVYNLATRPLAEQVNQTSIDAPPGIDEFALAGLTPARCIEVAAPRVAQSPVSL 133 Query: 134 ECKLAMLEPYPRH---APSCHLVFGEVLVAHVQDDLLDADGKLDPGKVDLLFRMGGEW-Y 189 ECK+ ++ A + +VFGEV+ H+ LL DG D + R GG Y Sbjct: 134 ECKVTQVQQLAGIDGVALNTWMVFGEVVAVHIDRALLR-DGIYDTAAAQPILRAGGPADY 192 Query: 190 GRSVNAANFTLPRPR 204 + F + RPR Sbjct: 193 FEVLPQGRFRMYRPR 207 >AGl355 [R] COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 212 Score = 115 bits (289), Expect = 5e-26, Method: Compositional matrix adjust. Identities = 64/190 (33%), Positives = 101/190 (53%), Gaps = 5/190 (2%) Query: 1 MLIDFAELKPVEAYEWMSSLIVPRPIAWVSTLDAQGRANLAPFSFFQMVTGKPPTLLICP 60 M DF+ L+P Y +++ I PRPIA V+T G N AP SFF + + PP +++ Sbjct: 4 MEFDFSALEPQSRYRLLTNFIGPRPIALVTTRSEAGHNNAAPMSFFNVFSHDPPIVVLGI 63 Query: 61 LLQRGGKLKDTVLNIDERGEFVVNLATPAQAAQLNETSFPFEAGVSEFEACGVTAAPSQR 120 + G+ KDT++NI GEFV+N+ A + Q+ F+ V E +TA P + Sbjct: 64 QPKLSGEEKDTMVNIRRTGEFVINMVDMALSDQMLICGLGFDNEVDEMSMAQLTAKPCSK 123 Query: 121 VAPPRVAAAAASFECKLAMLEPYPRHAPSCHLVFGEVLVAHVQDDLLDADGK-LDPGKVD 179 + A + +FEC++ L YPR LV GEV+ HV ++ LD +G+ +DP + Sbjct: 124 IDASYAAQSPCAFECRVERLIGYPRRT----LVLGEVVHMHVHNECLDEEGRYVDPDRYQ 179 Query: 180 LLFRMGGEWY 189 + R+ + Y Sbjct: 180 PIARLHADNY 189 >AGpA605 [R] COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 235 Score = 115 bits (288), Expect = 6e-26, Method: Compositional matrix adjust. Identities = 67/195 (34%), Positives = 99/195 (50%), Gaps = 14/195 (7%) Query: 4 DFAELKPVEAYEWMSSLIVPRPIAWVSTLDAQGRANLAPFSFFQMVTGKPPTLLICPLLQ 63 DFA+L E Y+ + ++PRPIA V+T+D GR N PFSFF ++T P + I Sbjct: 23 DFAKLTERERYKILIGTVIPRPIALVTTVDRDGRPNAGPFSFFNVLTHDPAIVAIGVENY 82 Query: 64 RGGKLKDTVLNIDERGEFVVNLATPAQAAQLNETSFPFEAGVSEFEACGVTAAPSQRVAP 123 + KDT NI E GEF V++ A Q+ + F G++E E G+ + V Sbjct: 83 ADMRFKDTARNIRETGEFTVHICDNALVDQMEICAIKFGPGINEMEEAGLETVKGEMVCS 142 Query: 124 PRVAAAAASFECKLAMLEPYPRH-----APSCHLVFGEVLVAHVQDDLLDADG-KLDPGK 177 PRV AA A+ EC+ RH P+ ++ GEV+ ++ D + A +D Sbjct: 143 PRVLAAPAALECR--------RHTTLQVGPAREIILGEVVGVFIRSDAVSASNLHIDQQM 194 Query: 178 VDLLFRMGGEWYGRS 192 +D + RMGG Y R+ Sbjct: 195 MDAVGRMGGHTYART 209 >SMc02426 [R] COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family Sme Sinorhizobium meliloti Length = 208 Score = 112 bits (279), Expect = 7e-25, Method: Compositional matrix adjust. Identities = 64/190 (33%), Positives = 101/190 (53%), Gaps = 5/190 (2%) Query: 1 MLIDFAELKPVEAYEWMSSLIVPRPIAWVSTLDAQGRANLAPFSFFQMVTGKPPTLLICP 60 M DF E++P Y +++ I PRPIA V+T G +N AP SFF + + P +++ Sbjct: 1 MEFDFEEIEPQSRYRLLTNFIGPRPIALVTTRSESGHSNAAPMSFFNVFSHDPAIVVLGI 60 Query: 61 LLQRGGKLKDTVLNIDERGEFVVNLATPAQAAQLNETSFPFEAGVSEFEACGVTAAPSQR 120 + G+ KDT++NI GEF +++ A + Q+ F++ V E E G+ AA ++ Sbjct: 61 QPRLTGEPKDTMVNIRRSGEFAISMVDMALSQQMLICGLGFDSEVDELEMAGLKAARCRK 120 Query: 121 VAPPRVAAAAASFECKLAMLEPYPRHAPSCHLVFGEVLVAHVQDDLLDADGK-LDPGKVD 179 + A FEC++ L YPR LV GEV+ HV+ D LDA+G +DP + Sbjct: 121 IDVAYAEEAPCIFECRVERLIDYPRRT----LVLGEVVHMHVRRDCLDAEGHYVDPERYQ 176 Query: 180 LLFRMGGEWY 189 + R+ + Y Sbjct: 177 PIARLHADNY 186 >BH2278 [R] COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family Bha Bacillus halodurans Length = 209 Score = 105 bits (263), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 66/194 (34%), Positives = 97/194 (50%), Gaps = 5/194 (2%) Query: 12 EAYEWMSSLIVPRPIAWVSTLDAQGRANLAPFSFFQMVTGKPPTLLICPLLQRGGKLKDT 71 E Y + ++PRPIA+V+T G N APFSF+ ++T +PP + I + G KDT Sbjct: 12 ENYRLLIGAVLPRPIAFVTTKSKAGVVNAAPFSFYNVLTAEPPLIGISVGRKPDGTPKDT 71 Query: 72 VLNIDERGEFVVNLATPAQAAQLNETSFPFEAGVSEFEACGVTAAPSQRVAPPRVAAAAA 131 N E GEFVV++ +N +S P SE E G+T PS+ V+ P +A + Sbjct: 72 ARNGQEIGEFVVHVVDEQNVEAVNVSSIPLPPEESEVEYAGLTEVPSEVVSVPSLAESRI 131 Query: 132 SFECKLAMLEPYPRHA--PSCHLVFGEVLVAHVQDDLLDADGKLDPGKVDLLFRMGGEWY 189 ECK+ + P P+ + G V+ V DDL DG +D + + R+ G Y Sbjct: 132 RLECKVENVIPIGGKGGEPAADFLIGRVVHYEVADDLFQ-DGGIDTEALRPVSRLAGNEY 190 Query: 190 GRSVNAANFTLPRP 203 G+ F+L RP Sbjct: 191 GKY--GETFSLDRP 202 >DR2585 [R] COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family Dra Deinococcus radiodurans Length = 234 Score = 105 bits (262), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 70/189 (37%), Positives = 104/189 (55%), Gaps = 10/189 (5%) Query: 4 DFAELKPVEAYEWMSSLIVPRPIAWVSTLDAQGRA----NLAPFSFFQMVTGKPPTLLIC 59 D L Y+ +++ +VPRPIAWV T + NLAP+SFF ++ +PP + Sbjct: 14 DLTALPQSARYKLLTATVVPRPIAWVGTRGSGETGKLGFNLAPYSFFGLMGSEPPVVAFA 73 Query: 60 PLLQRGGKLKDTVLNIDERGEFVVNLATPAQAAQLNETSFPFEAGVSEFEACGVTAAPSQ 119 P + G KD+ LNI GEF V+L + A AA +N ++ F G+ E +A G+ AP + Sbjct: 74 PGDRADGTPKDSALNIGSGGEFTVSLVSAALAAVMNLSATDFPRGMDEAQALGIQLAPGR 133 Query: 120 RVAPPRVAAAAASFECKLAMLEPYPRHAPSCHLVFGEVLVAHVQDD-LLDADG-KLDPGK 177 RV P VAAA A+ EC+ R ++ GEVL +++D +LDA+ +D Sbjct: 134 RVQVPHVAAAPAALECREVQTVSIGR----TRIILGEVLGLWLREDAVLDAEKHHVDTAA 189 Query: 178 VDLLFRMGG 186 +DL+ RMGG Sbjct: 190 LDLVGRMGG 198