BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0176.p (258 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CC1201 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related ... 177 3e-44 PA3430 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related ... 175 7e-44 RSc0806 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related... 132 6e-31 SPBC1289.14 [G] COG0235 Ribulose-5-phosphate 4-epimerase and rel... 132 7e-31 RC0678 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related ... 123 4e-28 RP493 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related e... 120 2e-27 SMa1976 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related... 93 6e-19 RSc1767 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related... 89 9e-18 SPBC359.06 [G] COG0235 Ribulose-5-phosphate 4-epimerase and rela... 86 1e-16 all1723 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related... 83 7e-16 >CC1201 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Ccr Caulobacter vibrioides Length = 300 Score = 177 bits (448), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 86/213 (40%), Positives = 133/213 (62%), Gaps = 5/213 (2%) Query: 17 SDEEWALRIQLAHCYRLVDYLGWTEMIFNHISVRVPGPEHHYLVNPFALNYNEVTPANLL 76 S+ EW R+ LA YRLV GW +MIF HIS R+PGPEHH+L+NP+ + + E+T ++L+ Sbjct: 59 SEAEWQARVDLAALYRLVALHGWDDMIFTHISARIPGPEHHFLINPYGMFFGEITASSLV 118 Query: 77 KVGLDGQLAEPSDYQANPAGFALHSAIHGARDDLRCVIHTHTTPISAVTMKKSGFAHNDF 136 KV L+G + + + Y NPAGF +HSA+H AR+D V+H H+ AV+ K G Sbjct: 119 KVDLEGNVIDKTPYYINPAGFTIHSAVHAAREDAHYVMHLHSDQGVAVSAHKEGLLPLTQ 178 Query: 137 YGAQLFGRIGYHDFEGITLFAEEKERMLQSLGEKHILVLRNHGVAVCESDIERAFFLLWT 196 + + ++ YHD+EGI L EE+ER++ LG+K +L+LRNHG + + ++ Sbjct: 179 HSLIVLPQLAYHDYEGIALNLEERERIVADLGQKKLLMLRNHGTLSVGATAAECWLGMFF 238 Query: 197 VQRAAEIQVAGRSMGGEDQVL-----QDDVRQK 224 ++RA QV S+G ++ +L QD+VR++ Sbjct: 239 LERACAQQVMALSIGRDNVLLAPEAAQDEVRKQ 271 >PA3430 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Pae Pseudomonas aeruginosa Length = 259 Score = 175 bits (444), Expect = 7e-44, Method: Compositional matrix adjust. Identities = 85/200 (42%), Positives = 120/200 (60%), Gaps = 1/200 (0%) Query: 14 AHCSDEEWALRIQLAHCYRLVDYLGWTEMIFNHISVRVPGPEHHYLVNPFALNYNEVTPA 73 A S EW R+ LA CYRLV GW ++IF HIS +VPG E +L+NPF L ++E+T + Sbjct: 13 AQVSAAEWQTRVDLAACYRLVALHGWDDLIFTHISAKVPGTED-FLINPFGLMFHEITAS 71 Query: 74 NLLKVGLDGQLAEPSDYQANPAGFALHSAIHGARDDLRCVIHTHTTPISAVTMKKSGFAH 133 +L+KV G+ S Y+ NPAG+ +HSA+H R D+ CV+HTHT AV+ +K G Sbjct: 72 SLVKVDASGKKLMDSPYEINPAGYTIHSAVHEVRHDVECVLHTHTAAGIAVSCQKQGLLP 131 Query: 134 NDFYGAQLFGRIGYHDFEGITLFAEEKERMLQSLGEKHILVLRNHGVAVCESDIERAFFL 193 + + YH +EG+ L EEK R+ LG + L+L NHG+ C I F + Sbjct: 132 LSQQSLFVLSSLSYHAYEGVALNHEEKARLQADLGASNFLILPNHGLLTCGGSIADTFLM 191 Query: 194 LWTVQRAAEIQVAGRSMGGE 213 ++T+QRA E+QV +S G E Sbjct: 192 MFTLQRACEVQVMAQSGGAE 211 >RSc0806 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Rso Ralstonia solanacearum Length = 261 Score = 132 bits (333), Expect = 6e-31, Method: Compositional matrix adjust. Identities = 77/200 (38%), Positives = 113/200 (56%), Gaps = 5/200 (2%) Query: 17 SDEEWALRIQLAHCYRLVDYLGWTEMIFNHISVRVPGPEHHYLVNPFALNYNEVTPANLL 76 S+ E A+RI LA YRL GW ++I+ H+S VPG H+L+N F L ++E+T ++L+ Sbjct: 17 SEAERAVRIDLAAAYRLAALNGWDDLIYTHLSATVPGEPEHFLINAFGLAFDEITASSLV 76 Query: 77 KVGLDGQL-AEPSDYQANPA----GFALHSAIHGARDDLRCVIHTHTTPISAVTMKKSGF 131 K+ GQL + D A P+ GFALH+A+H AR D CVIH H T AV+ ++ G Sbjct: 77 KINRAGQLVGDWPDPAACPSVNVTGFALHAAVHAARPDAHCVIHLHNTAGIAVSAQQHGL 136 Query: 132 AHNDFYGAQLFGRIGYHDFEGITLFAEEKERMLQSLGEKHILVLRNHGVAVCESDIERAF 191 + + R+ YHD+EG+ EE R+ SLG ++LRNHG + A Sbjct: 137 LPLSQHALRFHRRLAYHDYEGLAFTQEEGARLTASLGGHRAMLLRNHGTLTVGRTVAEAH 196 Query: 192 FLLWTVQRAAEIQVAGRSMG 211 L+ T+ +A EIQ+ + G Sbjct: 197 VLMATLIKACEIQIQALTAG 216 >SPBC1289.14 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Spo Schizosaccharomyces pombe Length = 324 Score = 132 bits (332), Expect = 7e-31, Method: Compositional matrix adjust. Identities = 74/225 (32%), Positives = 123/225 (54%), Gaps = 11/225 (4%) Query: 17 SDEEWALRIQLAHCYRLVDYLGWTEMIFNHISVRVPGPE--HHYLVNPFALNYNEVTPAN 74 +DEE A RI+LA YRL W E I NH++ +V P+ +L+NP+ L Y E+T ++ Sbjct: 72 TDEEVATRIELAAAYRLFGLEHWNENILNHLTAKVEEPDGTASFLINPYGLRYGEITASS 131 Query: 75 LLKVGLDGQLAEPSD----YQANPAGFALHSAIHGARDDLRCVIHTHTTPISAVTMKKSG 130 L+KV DG + P + N AG+ +HSAIH AR D++ ++H H + V+ K G Sbjct: 132 LIKVDEDGNIKHPGVTGDVFGINRAGYVIHSAIHRARPDVKSIMHNHYPYAAGVSCVKHG 191 Query: 131 FAHNDFYGAQLFGRIGYHDFEGITLFAEEKERMLQSLGEKHILVLRNHGVAVCESDIERA 190 F Q G + YHD+ GI + E++ + + + K IL+LRNHG+ + A Sbjct: 192 FLELAQTSHQ-SGPVTYHDYHGIVVDKGEQKSLAEDIANKDILILRNHGIITAAESVGAA 250 Query: 191 FFLLWTVQRAAEIQV--AGRSMGGEDQVL--QDDVRQKCADLTQQ 231 ++L++ A EIQ + ++G + + + + +K D+T++ Sbjct: 251 YYLMYQFLAATEIQTHASANALGDMNNLFIPNNKLVEKTFDVTRE 295 >RC0678 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Rco Rickettsia conorii Length = 231 Score = 123 bits (309), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 65/209 (31%), Positives = 109/209 (52%), Gaps = 4/209 (1%) Query: 23 LRIQLAHCYRLVDYLGWTEMIFNHISVRVPGPEHHYLVNPFALNYNEVTPANLLKVGLDG 82 ++ LA YR++ YL + + H+S R P Y + PF L + EVT NLLKV LDG Sbjct: 3 IKYNLAAAYRIMAYLSLDDHTYTHLSAR-PKNAVFYYIYPFGLRFEEVTTENLLKVSLDG 61 Query: 83 QLAEPSDYQANPAGFALHSAIHGARDDLRCVIHTHTTPISAVTMKKSGFAHNDFYGAQLF 142 Q+ E +YQ N G+ +H +I+ R D+ + H HT AV+ K G + + Sbjct: 62 QILEGEEYQYNKTGYFIHGSIYKTRPDISAIFHYHTPAAIAVSALKCGLLPISQWALHFY 121 Query: 143 GRIGYHDFEGITLFAEEK-ERMLQSLGEKHILVLRNHGVAVCESDIERAFFLLWTVQRAA 201 RI YH++ + L A+++ R++ L + ++++LRNHG C I A F + +++A Sbjct: 122 DRISYHNYNSLVLDADKQSSRLVTDLKQNYVMLLRNHGAITCGKTIHEAMFYTYHLEQAC 181 Query: 202 EIQVAGRSMGGEDQVLQ--DDVRQKCADL 228 + Q S ++ ++ + +Q DL Sbjct: 182 KTQCLLNSTKEQELIIPSVEICKQTVKDL 210 >RP493 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Rpr Rickettsia prowazekii Length = 231 Score = 120 bits (302), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 60/196 (30%), Positives = 105/196 (53%), Gaps = 2/196 (1%) Query: 23 LRIQLAHCYRLVDYLGWTEMIFNHISVRVPGPEHHYLVNPFALNYNEVTPANLLKVGLDG 82 ++ LA Y+++ YL + + H+S R + +Y + PF L + EVT NLLKV LDG Sbjct: 3 IKYNLAAAYKIMAYLSLDDHTYTHLSARSKNADFYY-IYPFGLRFEEVTTENLLKVSLDG 61 Query: 83 QLAEPSDYQANPAGFALHSAIHGARDDLRCVIHTHTTPISAVTMKKSGFAHNDFYGAQLF 142 ++ E +YQ N G+ +H I+ AR D+ + H HT +AV+ K G + + Sbjct: 62 KILEGEEYQYNKTGYFIHGNIYKARPDVLAIFHYHTPASTAVSALKCGLLPISQWALHFY 121 Query: 143 GRIGYHDFEGITLFAEEKE-RMLQSLGEKHILVLRNHGVAVCESDIERAFFLLWTVQRAA 201 RI YHD+ + L A+++ + + L + ++++LRNHG C I A F + +++A Sbjct: 122 DRISYHDYNSLVLDADKQSTKFVNDLKQNYVMLLRNHGAITCGKTIHEAMFYTYHLEQAC 181 Query: 202 EIQVAGRSMGGEDQVL 217 + Q S ++ ++ Sbjct: 182 KTQCLLNSTIQQELII 197 >SMa1976 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Sme Sinorhizobium meliloti Length = 249 Score = 92.8 bits (229), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 65/200 (32%), Positives = 97/200 (48%), Gaps = 11/200 (5%) Query: 18 DEEWALRIQLAHCYRLVDYLGWTEMIFNHISVRVPGPEHHYLVNPFALNYNEVTPANLLK 77 +E W R+ LA C R G E I NH S VPG +LVN + E T ++LL Sbjct: 9 EEIWQARVDLAACLRAAARYGLEEGICNHFSALVPGHADVFLVNRLGWAFEEATASSLLI 68 Query: 78 VGLDGQLAEPSDYQANPAGFALHSAIHGARDDLRCVIHTHTTPISAVTMKK------SGF 131 DG + D + F +H+ +H A + HTH +A++M + +G Sbjct: 69 CDFDGNVLS-GDGEPEATAFFIHARLHKAAPRIGAAFHTHMPNATALSMIEGEPLEWAGQ 127 Query: 132 AHNDFYGAQLFGRIGYHDFEGITLFAEEKERMLQSLGEKHILVLRNHGVAVCESDIERAF 191 FYG + D+ G+ L E +R+ LG+K IL ++NHGV VC +I A+ Sbjct: 128 TALKFYGRTVVD----EDYNGLALDDREGDRLASVLGDKDILFMKNHGVMVCAPNIAEAW 183 Query: 192 FLLWTVQRAAEIQVAGRSMG 211 L+ ++RAAE+Q+ S G Sbjct: 184 DDLYYLERAAEVQLKAMSTG 203 >RSc1767 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Rso Ralstonia solanacearum Length = 268 Score = 89.0 bits (219), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 54/185 (29%), Positives = 93/185 (50%), Gaps = 10/185 (5%) Query: 26 QLAHCYRLVDYLGWTEMIFNHISVRVPGPEHHYLVNPFALNYNEVTPANLLKVGLDGQLA 85 +LA +RL G+ E + HI+ R P + VNPF +++++V +NL++ G + Sbjct: 35 RLAAAFRLFSKFGFDEGVAGHITARDPEVLDSFWVNPFGVHFSQVKVSNLIRCDHHGNVV 94 Query: 86 EPSDYQANPAGFALHSAIHGARDDLRCVIHTHTT---PISAVTMKKSGFAHN--DFYGAQ 140 E DY N A FA+HS +H AR D H+H+ S + K + FY Sbjct: 95 E-GDYPVNAAAFAIHSRVHQARPDAVAAAHSHSIYGRAWSTLGRKLDPLTQDVCAFYEDH 153 Query: 141 LFGRIGYHDFEGITLFAEEKERMLQSLGEKHILVLRNHGVAVCESDIERAFFLLWTVQRA 200 Y DF G+ + +E +R+ Q+LG +L+NHG+ ++ A + T++R+ Sbjct: 154 AL----YDDFGGVVVELDEGQRIAQALGGNKAAILQNHGLLTVGKTVDEAAWWFITMERS 209 Query: 201 AEIQV 205 ++Q+ Sbjct: 210 CQVQL 214 >SPBC359.06 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Spo Schizosaccharomyces pombe Length = 257 Score = 85.5 bits (210), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 46/190 (24%), Positives = 95/190 (50%), Gaps = 2/190 (1%) Query: 17 SDEEWALRIQLAHCYRLVDYLGWTEMIFNHISVRVPGPEHHYLVNPFALNYNEVTPANLL 76 + +W L +A +R+ G+ E H++VR P E+ + +NP + ++ + P++L+ Sbjct: 15 TKRKWMLN-HMAAAFRMFGRNGYNEGTAGHVTVRDPIDENTFWINPLEVPFSLMKPSDLV 73 Query: 77 KVGLDGQLAEPSDYQANPAGFALHSAIHGARDDLRCVIHTHTTPISAVTMKKSGFAHNDF 136 + DG++ S + N +GFA+H +H R ++ CV H H+ A + + Sbjct: 74 HINSDGEIIGGSKMKYNTSGFAIHYEMHKVRPEVICVCHVHSIYGKAFSALGKPLDMLNT 133 Query: 137 YGAQLFGRIG-YHDFEGITLFAEEKERMLQSLGEKHILVLRNHGVAVCESDIERAFFLLW 195 + G Y D + + EE R + L + ++++NHG+ + ++ A +LL Sbjct: 134 DCCVFYNNHGIYFDMDDVISMPEEGRRTAKGLADYKAVLVQNHGIMTVGTTVDEAAYLLS 193 Query: 196 TVQRAAEIQV 205 ++R+ +IQ+ Sbjct: 194 LMERSCQIQL 203 >all1723 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Nos Nostoc sp. PCC 7120 Length = 253 Score = 82.8 bits (203), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 60/211 (28%), Positives = 98/211 (46%), Gaps = 18/211 (8%) Query: 11 VQPAHCSDEEWAL--RIQLAHCYRLVDYLGWTEMIFNHISVRVPGPEHHYLVNPFALNYN 68 + P S EE L + +LA +RL G++E I HI+ R P H+ VNP + Sbjct: 8 LPPVFNSIEEERLHRKQRLAAAFRLFGKFGFSEGIAGHITARDPEFTDHFWVNPLGKYFG 67 Query: 69 EVTPANLLKVGLDGQLAEPSDYQANPAGFALHSAIHGARDDLRCVIHTHTTPISAVT--- 125 + ++L+ V DG + + D N A FA+HS IH AR D+ H H+ A + Sbjct: 68 HIRVSDLVLVNRDGDVVK-GDALINQAAFAIHSQIHEARPDVVAAAHAHSIYGKAWSSLG 126 Query: 126 -----MKKSGFAHNDFYGAQLFGRIGYHDFEGITLFAEEKERMLQSLGEKHILVLRNHGV 180 + + A FY D+ G+ L E +R+ ++LG L+LRNHG+ Sbjct: 127 RLLDPLTQDACA---FYEDHAL----LDDYTGVVLETSEGKRLAETLGNNKALILRNHGI 179 Query: 181 AVCESDIERAFFLLWTVQRAAEIQVAGRSMG 211 ++ A F +++R+ + Q+ + G Sbjct: 180 LTVGHTVDEAAFWYISLERSCQAQLLAEAAG 210