BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0173.p (1049 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0818 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia s... 1766 0.0 STM0475 [V] COG0841 Cation/multidrug efflux pump Sty Salmonella ... 1372 0.0 YPO3133 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pe... 1362 0.0 CC0807 [V] COG0841 Cation/multidrug efflux pump Ccr Caulobacter ... 1361 0.0 ZacrB [V] COG0841 Cation/multidrug efflux pump EcZ Escherichia c... 1355 0.0 ECs0515 [V] COG0841 Cation/multidrug efflux pump Ecs Escherichia... 1355 0.0 acrB [V] COG0841 Cation/multidrug efflux pump Eco Escherichia co... 1355 0.0 PA0426 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas ... 1352 0.0 STM3391 [V] COG0841 Cation/multidrug efflux pump Sty Salmonella ... 1344 0.0 acrF [V] COG0841 Cation/multidrug efflux pump Eco Escherichia co... 1332 0.0 >RSp0818 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia solanacearum Length = 1053 Score = 1766 bits (4574), Expect = 0.0, Method: Compositional matrix adjust. Identities = 871/1031 (84%), Positives = 948/1031 (91%) Query: 1 MARFFIDRPIFAWVLAIIVMLAGIVSVLTLPIAQYPAIAPPAIAITANYPGASAKTLEDT 60 MAR+FIDRPIFAWVLAIIVMLAG +S+ TLPIAQYP+IAPPA+AITA YPGASAKTLEDT Sbjct: 1 MARYFIDRPIFAWVLAIIVMLAGALSIATLPIAQYPSIAPPAVAITATYPGASAKTLEDT 60 Query: 61 VTQIIEQKMKGLDRLSYMASTSESSGSVTITLTFENGTNPDTAQVQVQNKLSLATPLLPS 120 VTQIIEQKMKGLD LSYMASTSESSG+VTITLTF+NGT+PDTAQVQVQNKL+LATPLLP Sbjct: 61 VTQIIEQKMKGLDHLSYMASTSESSGTVTITLTFDNGTDPDTAQVQVQNKLALATPLLPQ 120 Query: 121 EVQQQGITVTKSATNFLNVLAFTSEDGSMSGSDLSDYVAANVQDAISRVEGVGDTTLFGS 180 EVQQQG+ VTKSATNFLNVLAFTSEDGSM+GSDLSDYVAANVQDA+SRVEGVGDTTLFGS Sbjct: 121 EVQQQGVQVTKSATNFLNVLAFTSEDGSMNGSDLSDYVAANVQDALSRVEGVGDTTLFGS 180 Query: 181 QYAMRIWLDPNKLNSYGLTPLDVKNAIQAQNAQVSSGQLGGLPAAENQQINATITAQTRL 240 QYAMRIWLDP+KL+++ LTPLDVK AIQAQNAQVS+GQLGG+PAA+NQQINATIT+QTRL Sbjct: 181 QYAMRIWLDPHKLSNFSLTPLDVKTAIQAQNAQVSAGQLGGMPAADNQQINATITSQTRL 240 Query: 241 RTADQFQNIVLRTLTGGAQVKLRDVARIELGSESYTSVGRYNGKPAAGLAIKLATGANAL 300 +TA+ F NI+LRT GAQV+LRDVARIELGSESY++VGRYNGKPAAGLAIKLATGANAL Sbjct: 241 KTAEAFGNILLRTQADGAQVRLRDVARIELGSESYSTVGRYNGKPAAGLAIKLATGANAL 300 Query: 301 DTVKAIDKRVAELEKFFPTGMKVQKPYDTTPFVRISIEEVVRTLIEAVVLVFLVMYLFLQ 360 DTVKAID RVAELE FFP GMKVQKPYDTTPFVRISIEEVVRTL+EA+ LVFLVMYLFLQ Sbjct: 301 DTVKAIDARVAELEPFFPPGMKVQKPYDTTPFVRISIEEVVRTLVEAIALVFLVMYLFLQ 360 Query: 361 NFRATLIPTIAVPVVLLGTFGVLAVFGFTINTLTMFAMVLAIGLLVDDAIVVVENVERVM 420 NFRATLIPTIAVPVVLLGTFGVLA GFTINTLTMFAMVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NFRATLIPTIAVPVVLLGTFGVLAACGFTINTLTMFAMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 SEEGLPPKQATRKSMGQISGALVGVALVLAAVFVPMAFFSGSTGVIYRQFSITIVSAMTL 480 SEEGLPP++ATRKSMGQI+GAL+GVALVLAAVFVPMAFF GSTGVIYRQFSITIVSAMTL Sbjct: 421 SEEGLPPREATRKSMGQITGALIGVALVLAAVFVPMAFFKGSTGVIYRQFSITIVSAMTL 480 Query: 481 SVLVALVLTPALCATLLKPAAKGHALATTGFFGWFNRQFDRSNIRYQGIVRHMLGRGWRY 540 SVLVA+VLTPALCATLLKP KGHA ATTGFFGWFNR FDR N RYQGIVRHMLG+ RY Sbjct: 481 SVLVAMVLTPALCATLLKPVRKGHAQATTGFFGWFNRTFDRGNHRYQGIVRHMLGKQRRY 540 Query: 541 MAAYAVLLALVVAGFMKLPVGFLPDEDQGTLFAIMQLPSGATKARTDEVIRQVEQHFLVD 600 MA Y VL A+VV GFMKLPVGFLPDEDQGTLF + QLP GAT ART++V+RQVE HFLVD Sbjct: 541 MAMYGVLFAMVVVGFMKLPVGFLPDEDQGTLFVLAQLPPGATNARTEDVLRQVEHHFLVD 600 Query: 601 QKEAVSGVFAVSGFSFAGSGQNMGFAFIKLKPWDERKGPGLSVTDVAAKAGAAFANIRDA 660 QKEAVSGVF+V+GFSFAGSGQNMGFAF+KL+PW+ERKG LSV+ V A+A FA IRDA Sbjct: 601 QKEAVSGVFSVAGFSFAGSGQNMGFAFVKLRPWNERKGEALSVSGVVARAFGFFATIRDA 660 Query: 661 RVFAFAPPAVSELGNATGFDLMLKDEANLGHAALMQARNQLLGELMQDKRLVAVRPNGLE 720 RVFAFAPPAV+ELGNATGFDLML+D ANLGHAALMQARNQLLG L QD RLVAVRPNG E Sbjct: 661 RVFAFAPPAVAELGNATGFDLMLQDRANLGHAALMQARNQLLGTLSQDPRLVAVRPNGQE 720 Query: 721 DTPEFRLSVDTDKAGALGVAMSDINDTIATAWGSSYVNDFIDKGRVKKVMLQGDAQYRML 780 DTPEF+L +D KA LG+++SDIN T+ATAWGSSYVNDFID+GRVKKVMLQ DA +RM Sbjct: 721 DTPEFQLQIDAHKAETLGLSISDINSTLATAWGSSYVNDFIDRGRVKKVMLQADAPFRMN 780 Query: 781 PSDVDRWYVRNSAGTMVPFSAFSTASWTSGSPRLERYNGVPSMEILGMALPGAASSGEAM 840 P D+D+WYVRNSAGTMVPF+AF+ W+SGSPRLERYNGVPSMEILGMA PG+ASSGEA+ Sbjct: 781 PEDIDKWYVRNSAGTMVPFTAFARVDWSSGSPRLERYNGVPSMEILGMAKPGSASSGEAL 840 Query: 841 AIVEAALAKMPPGIGYEWTGLSLQEKASSGKTGILYGVSILIVFLALAALYESWAVPFSV 900 AIVEAA+ K+P GIGY WTGLSLQEKASSG+T +LY +SILIVFL LAALYESWA+PFSV Sbjct: 841 AIVEAAVTKLPAGIGYAWTGLSLQEKASSGQTTLLYTLSILIVFLCLAALYESWAIPFSV 900 Query: 901 ILVVPLGVFGALLGAMLTWKMNDVYFQVGLLTTIGLACKNAILIVEFAKDLYEHGKSLVE 960 I+VVPLGV GALLGA+LTWKMNDVYFQVGLLTTIGLA KNAILIVEFAK+L G +VE Sbjct: 901 IMVVPLGVLGALLGAILTWKMNDVYFQVGLLTTIGLASKNAILIVEFAKELNAQGMRVVE 960 Query: 961 ATMEAVRMRLRPILMTSLAFILGVLPMVLGSGAGAGAQHALGTAVIGGMLSGTVLAVFFV 1020 A M A RMRLRPILMTSLAFILGV+PMV GSGAGAGAQHALGTAVIGGMLSGTVLA+FFV Sbjct: 961 AAMTAARMRLRPILMTSLAFILGVVPMVTGSGAGAGAQHALGTAVIGGMLSGTVLAIFFV 1020 Query: 1021 PLFFVIIMTLF 1031 PLFFV++ LF Sbjct: 1021 PLFFVLVRGLF 1031 >STM0475 [V] COG0841 Cation/multidrug efflux pump Sty Salmonella typhimurium LT2 Length = 1049 Score = 1372 bits (3551), Expect = 0.0, Method: Compositional matrix adjust. Identities = 680/1052 (64%), Positives = 832/1052 (79%), Gaps = 7/1052 (0%) Query: 1 MARFFIDRPIFAWVLAIIVMLAGIVSVLTLPIAQYPAIAPPAIAITANYPGASAKTLEDT 60 M FFIDRPIFAWV+AII+MLAG +++L LP+AQYP IAPPA+ I+A YPGA AKT++DT Sbjct: 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISATYPGADAKTVQDT 60 Query: 61 VTQIIEQKMKGLDRLSYMASTSESSGSVTITLTFENGTNPDTAQVQVQNKLSLATPLLPS 120 VTQ+IEQ M G+D L YM+S S+S+G+V ITLTFE+GT+ D AQVQVQNKL LA PLLP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQ 120 Query: 121 EVQQQGITVTKSATNFLNVLAFTSEDGSMSGSDLSDYVAANVQDAISRVEGVGDTTLFGS 180 EVQQQG++V KS+++FL V+ + DG+M+ D+SDYVAAN++D ISR GVGD LFGS Sbjct: 121 EVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDPISRTSGVGDVQLFGS 180 Query: 181 QYAMRIWLDPNKLNSYGLTPLDVKNAIQAQNAQVSSGQLGGLPAAENQQINATITAQTRL 240 QYAMRIW++P +L Y LTP+DV NAI+AQNAQV++GQLGG P + QQ+NA+I AQTRL Sbjct: 181 QYAMRIWMNPTELTKYQLTPVDVINAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240 Query: 241 RTADQFQNIVLRTLTGGAQVKLRDVARIELGSESYTSVGRYNGKPAAGLAIKLATGANAL 300 + D+F I+L+ G+QV+LRDVA+IELG E+Y + ++NG+PA+GL IKLATGANAL Sbjct: 241 TSTDEFGKILLKVNQDGSQVRLRDVAKIELGGENYDVIAKFNGQPASGLGIKLATGANAL 300 Query: 301 DTVKAIDKRVAELEKFFPTGMKVQKPYDTTPFVRISIEEVVRTLIEAVVLVFLVMYLFLQ 360 DT AI + ++E FFP GMK+ PYDTTPFV+ISI EVV+TL+EA++LVFLVMYLFLQ Sbjct: 301 DTATAIRAELKKMEPFFPPGMKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQ 360 Query: 361 NFRATLIPTIAVPVVLLGTFGVLAVFGFTINTLTMFAMVLAIGLLVDDAIVVVENVERVM 420 NFRATLIPTIAVPVVLLGTF VLA FGF+INTLTMF MVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 SEEGLPPKQATRKSMGQISGALVGVALVLAAVFVPMAFFSGSTGVIYRQFSITIVSAMTL 480 +EEGLPPK+ATRKSMGQI GALVG+A+VL+AVF+PMAFF GSTG IYRQFSITIVSAM L Sbjct: 421 TEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALVLTPALCATLLKPAAKG-HALATTGFFGWFNRQFDRSNIRYQGIVRHMLGRGWR 539 SVLVAL+LTPALCAT+LKP AKG H GFFGWFNR FD+S Y V ++L R Sbjct: 481 SVLVALILTPALCATMLKPVAKGDHGEGKKGFFGWFNRLFDKSTHHYTDSVGNILRSTGR 540 Query: 540 YMAAYAVLLALVVAGFMKLPVGFLPDEDQGTLFAIMQLPSGATKARTDEVIRQVEQHFLV 599 Y+ Y +++ + F++LP FLPDEDQG ++QLP+GAT+ RT +V+ +V ++L Sbjct: 541 YLLLYLIIVVGMAYLFVRLPSSFLPDEDQGVFLTMVQLPAGATQERTQKVLDEVTDYYLN 600 Query: 600 DQKEAVSGVFAVSGFSFAGSGQNMGFAFIKLKPWDERKGPGLSVTDVAAKAGAAFANIRD 659 +K V VFAV+GF FAG GQN G AF+ LK W +R G V + +A AAF+ I+D Sbjct: 601 KEKANVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEKNKVEAITQRATAAFSQIKD 660 Query: 660 ARVFAFAPPAVSELGNATGFDLMLKDEANLGHAALMQARNQLLGELMQ-DKRLVAVRPNG 718 A VFAF PA+ ELG ATGFD L D+A LGH L QARNQL GE+ + LV VRPNG Sbjct: 661 AMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLFGEVAKYPDLLVGVRPNG 720 Query: 719 LEDTPEFRLSVDTDKAGALGVAMSDINDTIATAWGSSYVNDFIDKGRVKKVMLQGDAQYR 778 LEDTP+F++ +D +KA ALGV++SDIN T+ AWG SYVNDFID+GRVKKV + +A+YR Sbjct: 721 LEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYR 780 Query: 779 MLPSDVDRWYVRNSAGTMVPFSAFSTASWTSGSPRLERYNGVPSMEILGMALPGAASSGE 838 MLP D++ WYVR S G MVPFSAFS++ W GSPRLERYNG+PSMEILG A PG S+GE Sbjct: 781 MLPDDINDWYVRGSDGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPG-KSTGE 839 Query: 839 AMAIVEAALAKMPPGIGYEWTGLSLQEKASSGKTGILYGVSILIVFLALAALYESWAVPF 898 AMA++E +K+P GIGY+WTG+S QE+ S + LY +S+++VFL LAALYESW++PF Sbjct: 840 AMAMMEELASKLPSGIGYDWTGMSYQERLSGNQAPALYAISLIVVFLCLAALYESWSIPF 899 Query: 899 SVILVVPLGVFGALLGAMLTWKMNDVYFQVGLLTTIGLACKNAILIVEFAKDLYE-HGKS 957 SV+LVVPLGV GALL A NDVYFQVGLLTTIGL+ KNAILIVEFAKDL + GK Sbjct: 900 SVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKG 959 Query: 958 LVEATMEAVRMRLRPILMTSLAFILGVLPMVLGSGAGAGAQHALGTAVIGGMLSGTVLAV 1017 LVEAT+EAVRMRLRPILMTSLAF+LGV+P+V+ SGAG+GAQ+A+GT V+GGM++ TVLA+ Sbjct: 960 LVEATLEAVRMRLRPILMTSLAFMLGVMPLVISSGAGSGAQNAVGTGVLGGMVTATVLAI 1019 Query: 1018 FFVPLFFVIIMTLFGRKPADAPQGQPAISPEH 1049 FFVP+FFV++ F RK D S EH Sbjct: 1020 FFVPVFFVVVRRRFSRKSEDIEHSH---STEH 1048 >YPO3133 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pestis Length = 1050 Score = 1362 bits (3525), Expect = 0.0, Method: Compositional matrix adjust. Identities = 673/1049 (64%), Positives = 829/1049 (79%), Gaps = 3/1049 (0%) Query: 1 MARFFIDRPIFAWVLAIIVMLAGIVSVLTLPIAQYPAIAPPAIAITANYPGASAKTLEDT 60 MA+FFIDRPIFAWV+AII+MLAG ++++ LP+AQYP IAPPAI I ANYPGA A T+++T Sbjct: 1 MAKFFIDRPIFAWVIAIIIMLAGALAIMKLPVAQYPTIAPPAITIAANYPGADATTVQNT 60 Query: 61 VTQIIEQKMKGLDRLSYMASTSESSGSVTITLTFENGTNPDTAQVQVQNKLSLATPLLPS 120 VTQ+IEQ M G+D L YM+S+S+SSG+V +TLTF +GT+PD AQVQVQNKL LA PLLP Sbjct: 61 VTQVIEQNMNGIDNLLYMSSSSDSSGNVQLTLTFNSGTDPDIAQVQVQNKLQLAMPLLPQ 120 Query: 121 EVQQQGITVTKSATNFLNVLAFTSEDGSMSGSDLSDYVAANVQDAISRVEGVGDTTLFGS 180 EVQQQG++V KS+++FL V F SEDG+M D++DYV +N++D ISR GVGD LFGS Sbjct: 121 EVQQQGVSVEKSSSSFLMVAGFISEDGTMQQEDIADYVGSNIKDPISRTPGVGDVQLFGS 180 Query: 181 QYAMRIWLDPNKLNSYGLTPLDVKNAIQAQNAQVSSGQLGGLPAAENQQINATITAQTRL 240 QYAMRIW+DP+KLN+Y LTP+DV NAI+ QN QV++GQLGG P Q++N++I AQTRL Sbjct: 181 QYAMRIWMDPHKLNNYKLTPVDVINAIKIQNNQVAAGQLGGTPPVPGQELNSSIIAQTRL 240 Query: 241 RTADQFQNIVLRTLTGGAQVKLRDVARIELGSESYTSVGRYNGKPAAGLAIKLATGANAL 300 A++F I+L+ T G+QV+L+DVA ++LG+ESY + RYNGKPAAG+ IKLATGANAL Sbjct: 241 TNAEEFSQILLKVNTDGSQVRLKDVAIVKLGAESYNIIARYNGKPAAGIGIKLATGANAL 300 Query: 301 DTVKAIDKRVAELEKFFPTGMKVQKPYDTTPFVRISIEEVVRTLIEAVVLVFLVMYLFLQ 360 +T A+ +A+L+ FFP+G+ V PYDTTPFV+ISI EVV+TLIEA++LVFLVMYLFLQ Sbjct: 301 NTSAAVKAELAKLQPFFPSGLTVVYPYDTTPFVKISINEVVKTLIEAIILVFLVMYLFLQ 360 Query: 361 NFRATLIPTIAVPVVLLGTFGVLAVFGFTINTLTMFAMVLAIGLLVDDAIVVVENVERVM 420 NFRATLIPTIAVPVVLLGTF +L+ FG++INTLTMF MVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NFRATLIPTIAVPVVLLGTFAILSAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 SEEGLPPKQATRKSMGQISGALVGVALVLAAVFVPMAFFSGSTGVIYRQFSITIVSAMTL 480 EEGLPPK+AT+KSM QI GALVG+ALVL+AVFVPMAFF G+TG IYRQFSITIVSAM L Sbjct: 421 QEEGLPPKEATKKSMEQIQGALVGIALVLSAVFVPMAFFGGATGAIYRQFSITIVSAMVL 480 Query: 481 SVLVALVLTPALCATLLKPAAKGHALATTGFFGWFNRQFDRSNIRYQGIVRHMLGRGWRY 540 SVLVAL+LTPALCAT+LKP KG TGFFGWFN F++S Y V ++L RY Sbjct: 481 SVLVALILTPALCATMLKPIKKGDHGPKTGFFGWFNNMFEKSTHHYTDSVANILRSTGRY 540 Query: 541 MAAYAVLLALVVAGFMKLPVGFLPDEDQGTLFAIMQLPSGATKARTDEVIRQVEQHFLVD 600 + Y ++ + FM+LP FLP+EDQG ++QLP+GAT+ RT +V+ V ++L Sbjct: 541 LVIYLAIVIGMAVLFMRLPSSFLPEEDQGVFLTMVQLPAGATQERTQKVLNHVTDYYLDK 600 Query: 601 QKEAVSGVFAVSGFSFAGSGQNMGFAFIKLKPWDERKGPGLSVTDVAAKAGAAFANIRDA 660 +K V+ VF V+GF F+G GQN G AF+ LK WDERKG V + ++A AAF+ I+D Sbjct: 601 EKNVVNSVFTVNGFGFSGQGQNTGLAFVSLKNWDERKGEQNKVPAIVSRASAAFSKIKDG 660 Query: 661 RVFAFAPPAVSELGNATGFDLMLKDEANLGHAALMQARNQLLGELMQD-KRLVAVRPNGL 719 VFAF PA+ ELG ATGFD L D+ NLGH L ARNQLLG Q LV VRPNGL Sbjct: 661 MVFAFNLPAIVELGTATGFDFQLIDQGNLGHQQLTDARNQLLGMAAQHPDMLVGVRPNGL 720 Query: 720 EDTPEFRLSVDTDKAGALGVAMSDINDTIATAWGSSYVNDFIDKGRVKKVMLQGDAQYRM 779 EDTP+F++ VD +KA ALGVA+SDIN T+ +A G SYVNDFID+GRVKKV +Q DA +RM Sbjct: 721 EDTPQFKVEVDQEKAQALGVAISDINTTLGSAMGGSYVNDFIDRGRVKKVYVQADAPFRM 780 Query: 780 LPSDVDRWYVRNSAGTMVPFSAFSTASWTSGSPRLERYNGVPSMEILGMALPGAASSGEA 839 LP D+D+WYVRN+ G MV F+ FSTA W GSPRLERYNG+PSMEILG A PG S+GEA Sbjct: 781 LPDDIDKWYVRNNMGQMVSFATFSTAKWEYGSPRLERYNGLPSMEILGQAAPG-KSTGEA 839 Query: 840 MAIVEAALAKMPPGIGYEWTGLSLQEKASSGKTGILYGVSILIVFLALAALYESWAVPFS 899 M +++ AK+P G+GY+WTG+S QE+ S + LY +S+++VFL LAALYESW++PFS Sbjct: 840 MDLMQELAAKLPSGVGYDWTGMSYQERLSGNQAPALYAISLIVVFLCLAALYESWSIPFS 899 Query: 900 VILVVPLGVFGALLGAMLTWKMNDVYFQVGLLTTIGLACKNAILIVEFAKDLYE-HGKSL 958 V+LVVPLGV GALL A L NDVYFQVGLLTTIGL+ KNAILIVEFAKDL + GK L Sbjct: 900 VMLVVPLGVVGALLAATLRGLENDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL 959 Query: 959 VEATMEAVRMRLRPILMTSLAFILGVLPMVLGSGAGAGAQHALGTAVIGGMLSGTVLAVF 1018 VE+T+E+VRMRLRPILMTSLAFILGV+P+V+ SGAG+GAQ+A+GT V+GGM++ TVLA+F Sbjct: 960 VESTLESVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMITATVLAIF 1019 Query: 1019 FVPLFFVIIMTLFGRKPADAPQGQPAISP 1047 FVPLFFV++ F RK D P +P Sbjct: 1020 FVPLFFVVVRRRFSRKTDDIEHSHPVNTP 1048 >CC0807 [V] COG0841 Cation/multidrug efflux pump Ccr Caulobacter vibrioides Length = 1051 Score = 1361 bits (3523), Expect = 0.0, Method: Compositional matrix adjust. Identities = 681/1051 (64%), Positives = 837/1051 (79%), Gaps = 3/1051 (0%) Query: 1 MARFFIDRPIFAWVLAIIVMLAGIVSVLTLPIAQYPAIAPPAIAITANYPGASAKTLEDT 60 ++RFFIDRPIFAWV+AI++MLAG +++ TLPIAQYP IA P ++I+ANYPGASAKT+ED+ Sbjct: 2 LSRFFIDRPIFAWVIAIVIMLAGALAIRTLPIAQYPEIALPQVSISANYPGASAKTVEDS 61 Query: 61 VTQIIEQKMKGLDRLSYMASTSESSGSVTITLTFENGTNPDTAQVQVQNKLSLATPLLPS 120 VTQ+IEQKMKGLD L YM+STS+ SGS T+TLTF+ GT+ D AQVQVQNKL AT LLP Sbjct: 62 VTQVIEQKMKGLDGLDYMSSTSDGSGSATVTLTFKAGTDIDIAQVQVQNKLQTATALLPQ 121 Query: 121 EVQQQGITVTKSATNFLNVLAFTSEDGSMSGSDLSDYVAANVQDAISRVEGVGDTTLFGS 180 EVQQQG+TV KSA NF+ V+ SED +G+DL+DY+A+N+QD +SRV+GVGD LFGS Sbjct: 122 EVQQQGLTVAKSARNFMMVIGLYSEDPKTTGADLADYMASNLQDPLSRVDGVGDIQLFGS 181 Query: 181 QYAMRIWLDPNKLNSYGLTPLDVKNAIQAQNAQVSSGQLGGLPAAENQQINATITAQTRL 240 QYAMRIWLDP KL S+ LTP DV AI+AQNAQVS+GQ+GG P +NATITAQ+RL Sbjct: 182 QYAMRIWLDPQKLASFSLTPADVAAAIRAQNAQVSAGQIGGTPNLPGTGLNATITAQSRL 241 Query: 241 RTADQFQNIVLRTLTGGAQVKLRDVARIELGSESYTSVGRYNGKPAAGLAIKLATGANAL 300 +T +QF+ I+++ +GGA V+L DVAR+ELG+ESY S+ ++NG AAG+AIKLA GANAL Sbjct: 242 QTPEQFRQIIVKNTSGGATVRLSDVARVELGAESYASIAKFNGYQAAGMAIKLAPGANAL 301 Query: 301 DTVKAIDKRVAELEKFFPTGMKVQKPYDTTPFVRISIEEVVRTLIEAVVLVFLVMYLFLQ 360 DT A++ R+A+LEK FP K PYD+TPFV++SIEEVV+TL+EA++LVF+VM+LFLQ Sbjct: 302 DTAAAVNARMAQLEKNFPANYKYVIPYDSTPFVKLSIEEVVKTLVEAIILVFIVMFLFLQ 361 Query: 361 NFRATLIPTIAVPVVLLGTFGVLAVFGFTINTLTMFAMVLAIGLLVDDAIVVVENVERVM 420 N+RATLIPTIAVPVVLLGTFGVLA FG++INTLTMF +VLAIGLLVDDAIVVVENVERVM Sbjct: 362 NWRATLIPTIAVPVVLLGTFGVLAAFGYSINTLTMFGLVLAIGLLVDDAIVVVENVERVM 421 Query: 421 SEEGLPPKQATRKSMGQISGALVGVALVLAAVFVPMAFFSGSTGVIYRQFSITIVSAMTL 480 SEEGL PK+ATRKSM +I+GAL+G+ALVLAAVFVPMAFF GS GVIYRQFSITIVSAM L Sbjct: 422 SEEGLSPKEATRKSMNEITGALIGIALVLAAVFVPMAFFGGSQGVIYRQFSITIVSAMAL 481 Query: 481 SVLVALVLTPALCATLLKPAAKGHALATTGFFGWFNRQFDRSNIRYQGIVRHMLGRGWRY 540 SV+VALVLTPAL AT+LKP GH TGFFGWFNR F+ + RYQG VR +LG+ R+ Sbjct: 482 SVVVALVLTPALTATMLKPVKAGHHEEKTGFFGWFNRSFNDMSSRYQGSVRKILGKRGRW 541 Query: 541 MAAYAVLLALVVAGFMKLPVGFLPDEDQGTLFAIMQLPSGATKARTDEVIRQVEQHFLVD 600 MA YA ++ + F++LP FLP+EDQGT+F ++QLP+GAT+ +T V+ QV HFLV Sbjct: 542 MAIYAAIIVAMGLLFVRLPSAFLPEEDQGTMFTLVQLPAGATEEKTLAVLDQVRDHFLVG 601 Query: 601 QKEAVSGVFAVSGFSFAGSGQNMGFAFIKLKPWDERKGPGLSVTDVAAKAGAAFANIRDA 660 +KEAV VF VSGFSFAG+GQN G AF++LK ++ RK L VA +A AF+ RDA Sbjct: 602 EKEAVQSVFTVSGFSFAGAGQNAGLAFVRLKDFEHRKSANLKAQAVAGRAMGAFSQFRDA 661 Query: 661 RVFAFAPPAVSELGNATGFDLMLKDEANLGHAALMQARNQLLGELMQDKRLVAVRPNGLE 720 VFA PPAV ELGN++GFD L+D +GH ALM ARN +LG QD LV VRPNG + Sbjct: 662 MVFAIVPPAVQELGNSSGFDFQLQDVGGVGHEALMNARNMMLGMASQDPSLVGVRPNGQD 721 Query: 721 DTPEFRLSVDTDKAGALGVAMSDINDTIATAWGSSYVNDFIDKGRVKKVMLQGDAQYRML 780 DTP+ ++ VD KAGALG+ +DIN ++ AWG SYVNDFID+GRVKKV +Q DA +RM Sbjct: 722 DTPQLKIEVDQAKAGALGLTTADINSALSAAWGGSYVNDFIDRGRVKKVYMQADAPFRMT 781 Query: 781 PSDVDRWYVRNSAGTMVPFSAFSTASWTSGSPRLERYNGVPSMEILGMALPGAASSGEAM 840 P D++RWYVRN+ G MV F AF+TASWT GSPRLERYNG+ S+ I G PG SSG+A+ Sbjct: 782 PEDLNRWYVRNNQGQMVAFPAFATASWTYGSPRLERYNGLSSVNIQGAPAPG-KSSGDAI 840 Query: 841 AIVEAALAKMPPGIGYEWTGLSLQEKASSGKTGILYGVSILIVFLALAALYESWAVPFSV 900 A +E AK+PPG+GYEWTGLS QE + + LY +SIL+VFL LAALYESW++P +V Sbjct: 841 AAMEKIAAKLPPGVGYEWTGLSAQELEAGNQAPALYAISILVVFLLLAALYESWSIPLAV 900 Query: 901 ILVVPLGVFGALLGAMLTWKMNDVYFQVGLLTTIGLACKNAILIVEFAKDLYEHGKSLVE 960 I+V+PLGV GALL ND+YFQVGLLTT+GLA KNAILIVEFAKDLYE G L+E Sbjct: 901 IMVIPLGVIGALLATFARGLSNDIYFQVGLLTTMGLAAKNAILIVEFAKDLYEKGMGLIE 960 Query: 961 ATMEAVRMRLRPILMTSLAFILGVLPMVLGSGAGAGAQHALGTAVIGGMLSGTVLAVFFV 1020 AT+EAVR+RLRPI+MTSLAF+ GVLP+ + +GAG+GAQHA+GT VIGGM+S T+LA+FFV Sbjct: 961 ATLEAVRLRLRPIIMTSLAFVFGVLPLAISNGAGSGAQHAIGTGVIGGMISATLLAIFFV 1020 Query: 1021 PLFFVIIMTLFGRKP--ADAPQGQPAISPEH 1049 PLFFV++ +F K DA QGQ + + H Sbjct: 1021 PLFFVVVEKIFKPKHNGHDAAQGQVSSTEAH 1051 >ZacrB [V] COG0841 Cation/multidrug efflux pump EcZ Escherichia coli O157:H7 EDL933 Length = 1049 Score = 1355 bits (3508), Expect = 0.0, Method: Compositional matrix adjust. Identities = 656/1020 (64%), Positives = 813/1020 (79%), Gaps = 4/1020 (0%) Query: 1 MARFFIDRPIFAWVLAIIVMLAGIVSVLTLPIAQYPAIAPPAIAITANYPGASAKTLEDT 60 M FFIDRPIFAWV+AII+MLAG +++L LP+AQYP IAPPA+ I+A+YPGA AKT++DT Sbjct: 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDT 60 Query: 61 VTQIIEQKMKGLDRLSYMASTSESSGSVTITLTFENGTNPDTAQVQVQNKLSLATPLLPS 120 VTQ+IEQ M G+D L YM+S S+S+G+V ITLTFE+GT+ D AQVQVQNKL LA PLLP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQ 120 Query: 121 EVQQQGITVTKSATNFLNVLAFTSEDGSMSGSDLSDYVAANVQDAISRVEGVGDTTLFGS 180 EVQQQG+++ KS+++FL V+ + DG+M+ D+SDYVAAN++DAISR GVGD LFGS Sbjct: 121 EVQQQGVSIEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGS 180 Query: 181 QYAMRIWLDPNKLNSYGLTPLDVKNAIQAQNAQVSSGQLGGLPAAENQQINATITAQTRL 240 QYAMRIW++PN+LN + LTP+DV AI+AQNAQV++GQLGG P + QQ+NA+I AQTRL Sbjct: 181 QYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240 Query: 241 RTADQFQNIVLRTLTGGAQVKLRDVARIELGSESYTSVGRYNGKPAAGLAIKLATGANAL 300 + ++F I+L+ G++V LRDVA+IELG E+Y + +NG+PA+GL IKLATGANAL Sbjct: 241 TSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANAL 300 Query: 301 DTVKAIDKRVAELEKFFPTGMKVQKPYDTTPFVRISIEEVVRTLIEAVVLVFLVMYLFLQ 360 DT AI +A++E FFP+G+K+ PYDTTPFV+ISI EVV+TL+EA++LVFLVMYLFLQ Sbjct: 301 DTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQ 360 Query: 361 NFRATLIPTIAVPVVLLGTFGVLAVFGFTINTLTMFAMVLAIGLLVDDAIVVVENVERVM 420 NFRATLIPTIAVPVVLLGTF VLA FGF+INTLTMF MVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 SEEGLPPKQATRKSMGQISGALVGVALVLAAVFVPMAFFSGSTGVIYRQFSITIVSAMTL 480 +EEGLPPK+ATRKSMGQI GALVG+A+VL+AVFVPMAFF GSTG IYRQFSITIVSAM L Sbjct: 421 AEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALVLTPALCATLLKPAAKG-HALATTGFFGWFNRQFDRSNIRYQGIVRHMLGRGWR 539 SVLVAL+LTPALCAT+LKP AKG H GFFGWFNR F++S Y V +L R Sbjct: 481 SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGR 540 Query: 540 YMAAYAVLLALVVAGFMKLPVGFLPDEDQGTLFAIMQLPSGATKARTDEVIRQVEQHFLV 599 Y+ Y +++ + F++LP FLPDEDQG ++QLP+GAT+ RT +V+ +V ++L Sbjct: 541 YLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLT 600 Query: 600 DQKEAVSGVFAVSGFSFAGSGQNMGFAFIKLKPWDERKGPGLSVTDVAAKAGAAFANIRD 659 +K V VFAV+GF FAG GQN G AF+ LK W +R G V + +A AF+ I+D Sbjct: 601 KEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKD 660 Query: 660 ARVFAFAPPAVSELGNATGFDLMLKDEANLGHAALMQARNQLLGELMQD-KRLVAVRPNG 718 A VFAF PA+ ELG ATGFD L D+A LGH L QARNQLL E + L +VRPNG Sbjct: 661 AMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNG 720 Query: 719 LEDTPEFRLSVDTDKAGALGVAMSDINDTIATAWGSSYVNDFIDKGRVKKVMLQGDAQYR 778 LEDTP+F++ +D +KA ALGV+++DIN T+ AWG SYVNDFID+GRVKKV + +A+YR Sbjct: 721 LEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYR 780 Query: 779 MLPSDVDRWYVRNSAGTMVPFSAFSTASWTSGSPRLERYNGVPSMEILGMALPGAASSGE 838 MLP D+ WYVR + G MVPFSAFS++ W GSPRLERYNG+PSMEILG A PG S+GE Sbjct: 781 MLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPG-KSTGE 839 Query: 839 AMAIVEAALAKMPPGIGYEWTGLSLQEKASSGKTGILYGVSILIVFLALAALYESWAVPF 898 AM ++E +K+P G+GY+WTG+S QE+ S + LY +S+++VFL LAALYESW++PF Sbjct: 840 AMELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPF 899 Query: 899 SVILVVPLGVFGALLGAMLTWKMNDVYFQVGLLTTIGLACKNAILIVEFAKDLYE-HGKS 957 SV+LVVPLGV GALL A NDVYFQVGLLTTIGL+ KNAILIVEFAKDL + GK Sbjct: 900 SVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKG 959 Query: 958 LVEATMEAVRMRLRPILMTSLAFILGVLPMVLGSGAGAGAQHALGTAVIGGMLSGTVLAV 1017 L+EAT++AVRMRLRPILMTSLAFILGV+P+V+ +GAG+GAQ+A+GT V+GGM++ TVLA+ Sbjct: 960 LIEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAI 1019 >ECs0515 [V] COG0841 Cation/multidrug efflux pump Ecs Escherichia coli O157:H7 Length = 1049 Score = 1355 bits (3508), Expect = 0.0, Method: Compositional matrix adjust. Identities = 656/1020 (64%), Positives = 813/1020 (79%), Gaps = 4/1020 (0%) Query: 1 MARFFIDRPIFAWVLAIIVMLAGIVSVLTLPIAQYPAIAPPAIAITANYPGASAKTLEDT 60 M FFIDRPIFAWV+AII+MLAG +++L LP+AQYP IAPPA+ I+A+YPGA AKT++DT Sbjct: 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDT 60 Query: 61 VTQIIEQKMKGLDRLSYMASTSESSGSVTITLTFENGTNPDTAQVQVQNKLSLATPLLPS 120 VTQ+IEQ M G+D L YM+S S+S+G+V ITLTFE+GT+ D AQVQVQNKL LA PLLP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQ 120 Query: 121 EVQQQGITVTKSATNFLNVLAFTSEDGSMSGSDLSDYVAANVQDAISRVEGVGDTTLFGS 180 EVQQQG+++ KS+++FL V+ + DG+M+ D+SDYVAAN++DAISR GVGD LFGS Sbjct: 121 EVQQQGVSIEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGS 180 Query: 181 QYAMRIWLDPNKLNSYGLTPLDVKNAIQAQNAQVSSGQLGGLPAAENQQINATITAQTRL 240 QYAMRIW++PN+LN + LTP+DV AI+AQNAQV++GQLGG P + QQ+NA+I AQTRL Sbjct: 181 QYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240 Query: 241 RTADQFQNIVLRTLTGGAQVKLRDVARIELGSESYTSVGRYNGKPAAGLAIKLATGANAL 300 + ++F I+L+ G++V LRDVA+IELG E+Y + +NG+PA+GL IKLATGANAL Sbjct: 241 TSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANAL 300 Query: 301 DTVKAIDKRVAELEKFFPTGMKVQKPYDTTPFVRISIEEVVRTLIEAVVLVFLVMYLFLQ 360 DT AI +A++E FFP+G+K+ PYDTTPFV+ISI EVV+TL+EA++LVFLVMYLFLQ Sbjct: 301 DTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQ 360 Query: 361 NFRATLIPTIAVPVVLLGTFGVLAVFGFTINTLTMFAMVLAIGLLVDDAIVVVENVERVM 420 NFRATLIPTIAVPVVLLGTF VLA FGF+INTLTMF MVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 SEEGLPPKQATRKSMGQISGALVGVALVLAAVFVPMAFFSGSTGVIYRQFSITIVSAMTL 480 +EEGLPPK+ATRKSMGQI GALVG+A+VL+AVFVPMAFF GSTG IYRQFSITIVSAM L Sbjct: 421 AEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALVLTPALCATLLKPAAKG-HALATTGFFGWFNRQFDRSNIRYQGIVRHMLGRGWR 539 SVLVAL+LTPALCAT+LKP AKG H GFFGWFNR F++S Y V +L R Sbjct: 481 SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGR 540 Query: 540 YMAAYAVLLALVVAGFMKLPVGFLPDEDQGTLFAIMQLPSGATKARTDEVIRQVEQHFLV 599 Y+ Y +++ + F++LP FLPDEDQG ++QLP+GAT+ RT +V+ +V ++L Sbjct: 541 YLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLT 600 Query: 600 DQKEAVSGVFAVSGFSFAGSGQNMGFAFIKLKPWDERKGPGLSVTDVAAKAGAAFANIRD 659 +K V VFAV+GF FAG GQN G AF+ LK W +R G V + +A AF+ I+D Sbjct: 601 KEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKD 660 Query: 660 ARVFAFAPPAVSELGNATGFDLMLKDEANLGHAALMQARNQLLGELMQD-KRLVAVRPNG 718 A VFAF PA+ ELG ATGFD L D+A LGH L QARNQLL E + L +VRPNG Sbjct: 661 AMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNG 720 Query: 719 LEDTPEFRLSVDTDKAGALGVAMSDINDTIATAWGSSYVNDFIDKGRVKKVMLQGDAQYR 778 LEDTP+F++ +D +KA ALGV+++DIN T+ AWG SYVNDFID+GRVKKV + +A+YR Sbjct: 721 LEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYR 780 Query: 779 MLPSDVDRWYVRNSAGTMVPFSAFSTASWTSGSPRLERYNGVPSMEILGMALPGAASSGE 838 MLP D+ WYVR + G MVPFSAFS++ W GSPRLERYNG+PSMEILG A PG S+GE Sbjct: 781 MLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPG-KSTGE 839 Query: 839 AMAIVEAALAKMPPGIGYEWTGLSLQEKASSGKTGILYGVSILIVFLALAALYESWAVPF 898 AM ++E +K+P G+GY+WTG+S QE+ S + LY +S+++VFL LAALYESW++PF Sbjct: 840 AMELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPF 899 Query: 899 SVILVVPLGVFGALLGAMLTWKMNDVYFQVGLLTTIGLACKNAILIVEFAKDLYE-HGKS 957 SV+LVVPLGV GALL A NDVYFQVGLLTTIGL+ KNAILIVEFAKDL + GK Sbjct: 900 SVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKG 959 Query: 958 LVEATMEAVRMRLRPILMTSLAFILGVLPMVLGSGAGAGAQHALGTAVIGGMLSGTVLAV 1017 L+EAT++AVRMRLRPILMTSLAFILGV+P+V+ +GAG+GAQ+A+GT V+GGM++ TVLA+ Sbjct: 960 LIEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAI 1019 >acrB [V] COG0841 Cation/multidrug efflux pump Eco Escherichia coli K12 Length = 1049 Score = 1355 bits (3507), Expect = 0.0, Method: Compositional matrix adjust. Identities = 657/1020 (64%), Positives = 813/1020 (79%), Gaps = 4/1020 (0%) Query: 1 MARFFIDRPIFAWVLAIIVMLAGIVSVLTLPIAQYPAIAPPAIAITANYPGASAKTLEDT 60 M FFIDRPIFAWV+AII+MLAG +++L LP+AQYP IAPPA+ I+A+YPGA AKT++DT Sbjct: 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDT 60 Query: 61 VTQIIEQKMKGLDRLSYMASTSESSGSVTITLTFENGTNPDTAQVQVQNKLSLATPLLPS 120 VTQ+IEQ M G+D L YM+S S+S+G+V ITLTFE+GT+ D AQVQVQNKL LA PLLP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQ 120 Query: 121 EVQQQGITVTKSATNFLNVLAFTSEDGSMSGSDLSDYVAANVQDAISRVEGVGDTTLFGS 180 EVQQQG++V KS+++FL V+ + DG+M+ D+SDYVAAN++DAISR GVGD LFGS Sbjct: 121 EVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGS 180 Query: 181 QYAMRIWLDPNKLNSYGLTPLDVKNAIQAQNAQVSSGQLGGLPAAENQQINATITAQTRL 240 QYAMRIW++PN+LN + LTP+DV AI+AQNAQV++GQLGG P + QQ+NA+I AQTRL Sbjct: 181 QYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240 Query: 241 RTADQFQNIVLRTLTGGAQVKLRDVARIELGSESYTSVGRYNGKPAAGLAIKLATGANAL 300 + ++F I+L+ G++V LRDVA+IELG E+Y + +NG+PA+GL IKLATGANAL Sbjct: 241 TSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANAL 300 Query: 301 DTVKAIDKRVAELEKFFPTGMKVQKPYDTTPFVRISIEEVVRTLIEAVVLVFLVMYLFLQ 360 DT AI +A++E FFP+G+K+ PYDTTPFV+ISI EVV+TL+EA++LVFLVMYLFLQ Sbjct: 301 DTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQ 360 Query: 361 NFRATLIPTIAVPVVLLGTFGVLAVFGFTINTLTMFAMVLAIGLLVDDAIVVVENVERVM 420 NFRATLIPTIAVPVVLLGTF VLA FGF+INTLTMF MVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 SEEGLPPKQATRKSMGQISGALVGVALVLAAVFVPMAFFSGSTGVIYRQFSITIVSAMTL 480 +EEGLPPK+ATRKSMGQI GALVG+A+VL+AVFVPMAFF GSTG IYRQFSITIVSAM L Sbjct: 421 AEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALVLTPALCATLLKPAAKG-HALATTGFFGWFNRQFDRSNIRYQGIVRHMLGRGWR 539 SVLVAL+LTPALCAT+LKP AKG H GFFGWFNR F++S Y V +L R Sbjct: 481 SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGR 540 Query: 540 YMAAYAVLLALVVAGFMKLPVGFLPDEDQGTLFAIMQLPSGATKARTDEVIRQVEQHFLV 599 Y+ Y +++ + F++LP FLPDEDQG ++QLP+GAT+ RT +V+ +V ++L Sbjct: 541 YLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLT 600 Query: 600 DQKEAVSGVFAVSGFSFAGSGQNMGFAFIKLKPWDERKGPGLSVTDVAAKAGAAFANIRD 659 +K V VFAV+GF FAG GQN G AF+ LK W +R G V + +A AF+ I+D Sbjct: 601 KEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKD 660 Query: 660 ARVFAFAPPAVSELGNATGFDLMLKDEANLGHAALMQARNQLLGELMQD-KRLVAVRPNG 718 A VFAF PA+ ELG ATGFD L D+A LGH L QARNQLL E + L +VRPNG Sbjct: 661 AMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNG 720 Query: 719 LEDTPEFRLSVDTDKAGALGVAMSDINDTIATAWGSSYVNDFIDKGRVKKVMLQGDAQYR 778 LEDTP+F++ +D +KA ALGV+++DIN T+ AWG SYVNDFID+GRVKKV + +A+YR Sbjct: 721 LEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYR 780 Query: 779 MLPSDVDRWYVRNSAGTMVPFSAFSTASWTSGSPRLERYNGVPSMEILGMALPGAASSGE 838 MLP D+ WYVR + G MVPFSAFS++ W GSPRLERYNG+PSMEILG A PG S+GE Sbjct: 781 MLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPG-KSTGE 839 Query: 839 AMAIVEAALAKMPPGIGYEWTGLSLQEKASSGKTGILYGVSILIVFLALAALYESWAVPF 898 AM ++E +K+P G+GY+WTG+S QE+ S + LY +S+++VFL LAALYESW++PF Sbjct: 840 AMELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPF 899 Query: 899 SVILVVPLGVFGALLGAMLTWKMNDVYFQVGLLTTIGLACKNAILIVEFAKDLYE-HGKS 957 SV+LVVPLGV GALL A NDVYFQVGLLTTIGL+ KNAILIVEFAKDL + GK Sbjct: 900 SVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKG 959 Query: 958 LVEATMEAVRMRLRPILMTSLAFILGVLPMVLGSGAGAGAQHALGTAVIGGMLSGTVLAV 1017 L+EAT++AVRMRLRPILMTSLAFILGV+P+V+ +GAG+GAQ+A+GT V+GGM++ TVLA+ Sbjct: 960 LIEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAI 1019 >PA0426 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas aeruginosa Length = 1046 Score = 1352 bits (3498), Expect = 0.0, Method: Compositional matrix adjust. Identities = 662/1047 (63%), Positives = 825/1047 (78%), Gaps = 6/1047 (0%) Query: 1 MARFFIDRPIFAWVLAIIVMLAGIVSVLTLPIAQYPAIAPPAIAITANYPGASAKTLEDT 60 M++FFIDRPIFAWV+A+++MLAG +S+L+LP+ QYPAIAPPAIA+ +YPGASA+T++DT Sbjct: 1 MSKFFIDRPIFAWVIALVIMLAGGLSILSLPVNQYPAIAPPAIAVQVSYPGASAETVQDT 60 Query: 61 VTQIIEQKMKGLDRLSYMASTSESSGSVTITLTFENGTNPDTAQVQVQNKLSLATPLLPS 120 V Q+IEQ+M G+D L Y++S S S GS+TIT+TFE GT+PD AQVQVQNKL LATPLLP Sbjct: 61 VVQVIEQQMNGIDNLRYISSESNSDGSMTITVTFEQGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQQQGITVTKSATNFLNVLAFTSEDGSMSGSDLSDYVAANVQDAISRVEGVGDTTLFGS 180 EVQ+QGI VTK+ NFL V+ S DGSM+ DLS+Y+ +N+QD +SR +GVGD +FGS Sbjct: 121 EVQRQGIRVTKAVKNFLMVVGVVSTDGSMTKEDLSNYIVSNIQDPLSRTKGVGDFQVFGS 180 Query: 181 QYAMRIWLDPNKLNSYGLTPLDVKNAIQAQNAQVSSGQLGGLPAAENQQINATITAQTRL 240 QY+MRIWLDP KLNSY LTP DV +AIQAQN Q+SSGQLGGLPA + QQ+NATI +TRL Sbjct: 181 QYSMRIWLDPAKLNSYQLTPGDVSSAIQAQNVQISSGQLGGLPAVKGQQLNATIIGKTRL 240 Query: 241 RTADQFQNIVLRTLTGGAQVKLRDVARIELGSESYTSVGRYNGKPAAGLAIKLATGANAL 300 +TA+QF+NI+L+ G+QV+L+DVA + LG + Y+ ++NG PA+G+AIKLATGANAL Sbjct: 241 QTAEQFENILLKVNPDGSQVRLKDVADVGLGGQDYSINAQFNGSPASGIAIKLATGANAL 300 Query: 301 DTVKAIDKRVAELEKFFPTGMKVQKPYDTTPFVRISIEEVVRTLIEAVVLVFLVMYLFLQ 360 DT KAI + +A LE F P GMKV PYDTTP V SI EVV+TL EA++LVFLVMYLFLQ Sbjct: 301 DTAKAIRQTIANLEPFMPQGMKVVYPYDTTPVVSASIHEVVKTLGEAILLVFLVMYLFLQ 360 Query: 361 NFRATLIPTIAVPVVLLGTFGVLAVFGFTINTLTMFAMVLAIGLLVDDAIVVVENVERVM 420 NFRATLIPTIAVPVVLLGTFGVLA FGF+INTLTMF MVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NFRATLIPTIAVPVVLLGTFGVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 SEEGLPPKQATRKSMGQISGALVGVALVLAAVFVPMAFFSGSTGVIYRQFSITIVSAMTL 480 +EEGL P++A RKSMGQI GALVG+A+VL+AVF+PMAFF GSTGVIYRQFSITIVSAM L Sbjct: 421 AEEGLSPREAARKSMGQIQGALVGIAMVLSAVFLPMAFFGGSTGVIYRQFSITIVSAMAL 480 Query: 481 SVLVALVLTPALCATLLKPAAKG-HALATTGFFGWFNRQFDRSNIRYQGIVRHMLGRGWR 539 SV+VAL+LTPALCAT+LKP KG H GFFGWFNR F + Y+ V +L Sbjct: 481 SVIVALILTPALCATMLKPIEKGDHGEHKGGFFGWFNRMFLSTTHGYERGVASILKHRAP 540 Query: 540 YMAAYAVLLALVVAGFMKLPVGFLPDEDQGTLFAIMQLPSGATKARTDEVIRQVEQHFLV 599 Y+ Y V++A ++ F ++P FLPDEDQG LFA +Q P G++ RT V+ + ++ L Sbjct: 541 YLLIYVVIVAGMIWMFTRIPTAFLPDEDQGVLFAQVQTPPGSSAERTQVVVDSMREYLLE 600 Query: 600 DQKEAVSGVFAVSGFSFAGSGQNMGFAFIKLKPWDERKGPGLSVTDVAAKAGAAFANIRD 659 + +VS VF V+GF+FAG GQ+ G AFI LKPW+ER G SV ++A +A F + +D Sbjct: 601 KESSSVSSVFTVTGFNFAGRGQSSGMAFIMLKPWEERPGGENSVFELAKRAQMHFFSFKD 660 Query: 660 ARVFAFAPPAVSELGNATGFDLMLKDEANLGHAALMQARNQLLGELMQDKRLVAVRPNGL 719 A VFAFAPP+V ELGNATGFDL L+D+A +GH L+QARN+ L Q+ L VRPNG+ Sbjct: 661 AMVFAFAPPSVLELGNATGFDLFLQDQAGVGHEVLLQARNKFLMLAAQNPALQRVRPNGM 720 Query: 720 EDTPEFRLSVDTDKAGALGVAMSDINDTIATAWGSSYVNDFIDKGRVKKVMLQGDAQYRM 779 D P+++L +D +KA ALGV+++DIN T++ AWGSSYVNDFID+GRVK+V LQG RM Sbjct: 721 SDEPQYKLEIDDEKASALGVSLADINSTVSIAWGSSYVNDFIDRGRVKRVYLQGRPDARM 780 Query: 780 LPSDVDRWYVRNSAGTMVPFSAFSTASWTSGSPRLERYNGVPSMEILGMALPGAASSGEA 839 P D+ +WYVRN G MVPF+AF+T W GSP+LERYNGVP+MEILG PG SSG+A Sbjct: 781 NPDDLSKWYVRNDKGEMVPFNAFATGKWEYGSPKLERYNGVPAMEILGEPAPG-LSSGDA 839 Query: 840 MAIVEAALAKMPPGIGYEWTGLSLQEKASSGKTGILYGVSILIVFLALAALYESWAVPFS 899 MA VE + ++P G+GY WTGLS +E+ S + LY +S+L+VFL LAALYESW++PFS Sbjct: 840 MAAVEEIVKQLPKGVGYSWTGLSYEERLSGSQAPALYALSLLVVFLCLAALYESWSIPFS 899 Query: 900 VILVVPLGVFGALLGAMLTWKMNDVYFQVGLLTTIGLACKNAILIVEFAKDLYEHGKSLV 959 V+LVVPLGV GALL + NDV+FQVGLLTTIGL+ KNAILIVEFAK+L+E GK +V Sbjct: 900 VMLVVPLGVIGALLATSMRGLSNDVFFQVGLLTTIGLSAKNAILIVEFAKELHEQGKGIV 959 Query: 960 EATMEAVRMRLRPILMTSLAFILGVLPMVLGSGAGAGAQHALGTAVIGGMLSGTVLAVFF 1019 EA +EA RMRLRPI+MTSLAFILGV+P+ + +GAG+G+QHA+GT VIGGM++ TVLA+F+ Sbjct: 960 EAAIEACRMRLRPIVMTSLAFILGVVPLAISTGAGSGSQHAIGTGVIGGMVTATVLAIFW 1019 Query: 1020 VPLFFVIIMTLF----GRKPADAPQGQ 1042 VPLF+V + TLF ++ A +GQ Sbjct: 1020 VPLFYVAVSTLFKDEASKQQASVEKGQ 1046 >STM3391 [V] COG0841 Cation/multidrug efflux pump Sty Salmonella typhimurium LT2 Length = 1037 Score = 1344 bits (3479), Expect = 0.0, Method: Compositional matrix adjust. Identities = 657/1019 (64%), Positives = 808/1019 (79%), Gaps = 3/1019 (0%) Query: 1 MARFFIDRPIFAWVLAIIVMLAGIVSVLTLPIAQYPAIAPPAIAITANYPGASAKTLEDT 60 MA FFI RPIFAWVLAII+M+AG ++++ LP+AQYP IAPPA++I+A YPGA A+T++DT Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAIMQLPVAQYPTIAPPAVSISATYPGADAQTVQDT 60 Query: 61 VTQIIEQKMKGLDRLSYMASTSESSGSVTITLTFENGTNPDTAQVQVQNKLSLATPLLPS 120 VTQ+IEQ M G+D L YM+STS+S+GSVTITLTF++GT+PD AQVQVQNKL LATPLLP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQQQGITVTKSATNFLNVLAFTSEDGSMSGSDLSDYVAANVQDAISRVEGVGDTTLFGS 180 EVQQQGI+V KS+++FL V F S++ + + D+SDYVA+N++D+ISR+ GVGD LFG+ Sbjct: 121 EVQQQGISVEKSSSSFLMVAGFVSDNPNTTQDDISDYVASNIKDSISRLNGVGDVQLFGA 180 Query: 181 QYAMRIWLDPNKLNSYGLTPLDVKNAIQAQNAQVSSGQLGGLPAAENQQINATITAQTRL 240 QYAMRIWLD N LN Y LTP+DV N ++ QN Q+++GQLGG PA QQ+NA+I AQTRL Sbjct: 181 QYAMRIWLDANLLNKYQLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRL 240 Query: 241 RTADQFQNIVLRTLTGGAQVKLRDVARIELGSESYTSVGRYNGKPAAGLAIKLATGANAL 300 + ++F + LR T G+ V L+DVARIELG E+Y V R NGKPA+GL IKLATGANAL Sbjct: 241 KDPEEFGKVTLRVNTDGSVVHLKDVARIELGGENYNVVARINGKPASGLGIKLATGANAL 300 Query: 301 DTVKAIDKRVAELEKFFPTGMKVQKPYDTTPFVRISIEEVVRTLIEAVVLVFLVMYLFLQ 360 DT AI ++AEL+ FFP GMKV PYDTTPFV+ISI EVV+TL EA++LVFLVMYLFLQ Sbjct: 301 DTATAIKVKLAELQPFFPQGMKVVYPYDTTPFVKISIHEVVKTLFEAIILVFLVMYLFLQ 360 Query: 361 NFRATLIPTIAVPVVLLGTFGVLAVFGFTINTLTMFAMVLAIGLLVDDAIVVVENVERVM 420 N RATLIPTIAVPVVLLGTF VLA FG++INTLTMF MVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NIRATLIPTIAVPVVLLGTFAVLAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 SEEGLPPKQATRKSMGQISGALVGVALVLAAVFVPMAFFSGSTGVIYRQFSITIVSAMTL 480 E+ L P++AT KSM QI GALVG+A+VL+AVF+PMAFF GSTG IYRQFSITIVSAM L Sbjct: 421 MEDNLSPREATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALVLTPALCATLLKPAAKGHALATTGFFGWFNRQFDRSNIRYQGIVRHMLGRGWRY 540 SVLVAL+LTPALCATLLKP + H +GFFGWFN +FD S Y V ++ RY Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHEKKSGFFGWFNTRFDHSVNHYTNSVSGIVRNTGRY 540 Query: 541 MAAYAVLLALVVAGFMKLPVGFLPDEDQGTLFAIMQLPSGATKARTDEVIRQVEQHFLVD 600 + Y +++ + F++LP FLP+EDQG ++QLPSGAT+ RT +V+ QV ++L + Sbjct: 541 LIIYLLIVVGMAVLFLRLPTSFLPEEDQGVFLTMIQLPSGATQERTQKVLDQVTHYYLNN 600 Query: 601 QKEAVSGVFAVSGFSFAGSGQNMGFAFIKLKPWDERKGPGLSVTDVAAKAGAAFANIRDA 660 +K V VF V+GFSF+G GQN G AF+ LKPW+ER G SV V A+A AF+ IRD Sbjct: 601 EKANVESVFTVNGFSFSGQGQNSGMAFVSLKPWEERNGEENSVEAVIARATRAFSQIRDG 660 Query: 661 RVFAFAPPAVSELGNATGFDLMLKDEANLGHAALMQARNQLLGELMQDKR-LVAVRPNGL 719 VF F PA+ ELG ATGFD L D+ LGH AL +ARNQLLG + + LV VRPNGL Sbjct: 661 LVFPFNMPAIVELGTATGFDFELIDQGGLGHDALTKARNQLLGMVAKHPDLLVRVRPNGL 720 Query: 720 EDTPEFRLSVDTDKAGALGVAMSDINDTIATAWGSSYVNDFIDKGRVKKVMLQGDAQYRM 779 EDTP+F+L VD +KA ALGV++SDIN+TI+ A G YVNDFID+GRVKKV +Q DAQ+RM Sbjct: 721 EDTPQFKLDVDQEKAQALGVSLSDINETISAALGGYYVNDFIDRGRVKKVYVQADAQFRM 780 Query: 780 LPSDVDRWYVRNSAGTMVPFSAFSTASWTSGSPRLERYNGVPSMEILGMALPGAASSGEA 839 LP D++ YVR++ G MVPFS FS+A W GSPRLERYNG+PSME+LG A PG S+GEA Sbjct: 781 LPGDINNLYVRSANGEMVPFSTFSSARWIYGSPRLERYNGMPSMELLGEAAPG-RSTGEA 839 Query: 840 MAIVEAALAKMPPGIGYEWTGLSLQEKASSGKTGILYGVSILIVFLALAALYESWAVPFS 899 M+++E +++P GIGY+WTG+S QE+ S + LY +S+++VFL LAALYESW++PFS Sbjct: 840 MSLMENLASQLPNGIGYDWTGMSYQERLSGNQAPALYAISLIVVFLCLAALYESWSIPFS 899 Query: 900 VILVVPLGVFGALLGAMLTWKMNDVYFQVGLLTTIGLACKNAILIVEFAKDLYE-HGKSL 958 V+LVVPLGV GALL A L NDVYFQVGLLTTIGL+ KNAILIVEFAKDL E G+ L Sbjct: 900 VMLVVPLGVVGALLAASLRGLNNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMEKEGRGL 959 Query: 959 VEATMEAVRMRLRPILMTSLAFILGVLPMVLGSGAGAGAQHALGTAVIGGMLSGTVLAV 1017 +EAT+EA RMRLRPILMTSLAFILGV+P+V+ GAG+GAQ+A+GT V+GGML+ T+LA+ Sbjct: 960 IEATLEASRMRLRPILMTSLAFILGVMPLVISRGAGSGAQNAVGTGVMGGMLTATLLAI 1018 >acrF [V] COG0841 Cation/multidrug efflux pump Eco Escherichia coli K12 Length = 1034 Score = 1332 bits (3446), Expect = 0.0, Method: Compositional matrix adjust. Identities = 652/1019 (63%), Positives = 801/1019 (78%), Gaps = 3/1019 (0%) Query: 1 MARFFIDRPIFAWVLAIIVMLAGIVSVLTLPIAQYPAIAPPAIAITANYPGASAKTLEDT 60 MA FFI RPIFAWVLAII+M+AG +++L LP+AQYP IAPPA++++ANYPGA A+T++DT Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQIIEQKMKGLDRLSYMASTSESSGSVTITLTFENGTNPDTAQVQVQNKLSLATPLLPS 120 VTQ+IEQ M G+D L YM+STS+S+GSVTITLTF++GT+PD AQVQVQNKL LATPLLP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQQQGITVTKSATNFLNVLAFTSEDGSMSGSDLSDYVAANVQDAISRVEGVGDTTLFGS 180 EVQQQGI+V KS++++L V F S++ + D+SDYVA+NV+D +SR+ GVGD LFG+ Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYAMRIWLDPNKLNSYGLTPLDVKNAIQAQNAQVSSGQLGGLPAAENQQINATITAQTRL 240 QYAMRIWLD + LN Y LTP+DV N ++ QN Q+++GQLGG PA QQ+NA+I AQTR Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 RTADQFQNIVLRTLTGGAQVKLRDVARIELGSESYTSVGRYNGKPAAGLAIKLATGANAL 300 + ++F + LR + G+ V+L+DVAR+ELG E+Y + R NGKPAAGL IKLATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTVKAIDKRVAELEKFFPTGMKVQKPYDTTPFVRISIEEVVRTLIEAVVLVFLVMYLFLQ 360 DT KAI ++AEL+ FFP GMKV PYDTTPFV++SI EVV+TL EA++LVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NFRATLIPTIAVPVVLLGTFGVLAVFGFTINTLTMFAMVLAIGLLVDDAIVVVENVERVM 420 N RATLIPTIAVPVVLLGTF +LA FG++INTLTMF MVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 SEEGLPPKQATRKSMGQISGALVGVALVLAAVFVPMAFFSGSTGVIYRQFSITIVSAMTL 480 E+ LPPK+AT KSM QI GALVG+A+VL+AVF+PMAFF GSTG IYRQFSITIVSAM L Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALVLTPALCATLLKPAAKGHALATTGFFGWFNRQFDRSNIRYQGIVRHMLGRGWRY 540 SVLVAL+LTPALCATLLKP + H GFFGWFN FD S Y V +LG RY Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 541 MAAYAVLLALVVAGFMKLPVGFLPDEDQGTLFAIMQLPSGATKARTDEVIRQVEQHFLVD 600 + YA+++A +V F++LP FLP+EDQG ++QLP+GAT+ RT +V+ QV ++L + Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 601 QKEAVSGVFAVSGFSFAGSGQNMGFAFIKLKPWDERKGPGLSVTDVAAKAGAAFANIRDA 660 +K V VF V+GFSF+G QN G AF+ LKPW+ER G S V +A IRD Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 661 RVFAFAPPAVSELGNATGFDLMLKDEANLGHAALMQARNQLLGELMQD-KRLVAVRPNGL 719 V F PA+ ELG ATGFD L D+A LGH AL QARNQLLG Q LV+VRPNGL Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 720 EDTPEFRLSVDTDKAGALGVAMSDINDTIATAWGSSYVNDFIDKGRVKKVMLQGDAQYRM 779 EDT +F+L VD +KA ALGV++SDIN TI+TA G +YVNDFID+GRVKK+ +Q DA++RM Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 780 LPSDVDRWYVRNSAGTMVPFSAFSTASWTSGSPRLERYNGVPSMEILGMALPGAASSGEA 839 LP DVD+ YVR++ G MVPFSAF+T+ W GSPRLERYNG+PSMEI G A PG SSG+A Sbjct: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPG-TSSGDA 839 Query: 840 MAIVEAALAKMPPGIGYEWTGLSLQEKASSGKTGILYGVSILIVFLALAALYESWAVPFS 899 MA++E +K+P GIGY+WTG+S QE+ S + L +S ++VFL LAALYESW++P S Sbjct: 840 MALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVS 899 Query: 900 VILVVPLGVFGALLGAMLTWKMNDVYFQVGLLTTIGLACKNAILIVEFAKDLYE-HGKSL 958 V+LVVPLG+ G LL A L + NDVYF VGLLTTIGL+ KNAILIVEFAKDL E GK + Sbjct: 900 VMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGV 959 Query: 959 VEATMEAVRMRLRPILMTSLAFILGVLPMVLGSGAGAGAQHALGTAVIGGMLSGTVLAV 1017 VEAT+ AVRMRLRPILMTSLAFILGVLP+ + +GAG+GAQ+A+G V+GGM+S T+LA+ Sbjct: 960 VEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAI 1018