BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0167.p (578 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0020 [P] COG0038 Chloride channel protein EriC Rso Ralstonia ... 437 e-122 YPO2270 [P] COG0038 Chloride channel protein EriC Ype Yersinia p... 249 1e-65 ynfJ [P] COG0038 Chloride channel protein EriC Eco Escherichia c... 202 2e-51 Z2583 [P] COG0038 Chloride channel protein EriC EcZ Escherichia ... 202 3e-51 ECs2298 [P] COG0038 Chloride channel protein EriC Ecs Escherichi... 202 3e-51 STM1490 [P] COG0038 Chloride channel protein EriC Sty Salmonella... 200 7e-51 MA3609_1 [P] COG0038 Chloride channel protein EriC Mac Methanosa... 166 1e-40 AF1415_1 [P] COG0038 Chloride channel protein EriC Afu Archaeogl... 145 3e-34 sll0855 [P] COG0038 Chloride channel protein EriC Syn Synechocystis 143 1e-33 alr4891_1 [P] COG0038 Chloride channel protein EriC Nos Nostoc s... 140 6e-33 >RSp0020 [P] COG0038 Chloride channel protein EriC Rso Ralstonia solanacearum Length = 461 Score = 437 bits (1123), Expect = e-122, Method: Compositional matrix adjust. Identities = 237/443 (53%), Positives = 309/443 (69%), Gaps = 9/443 (2%) Query: 4 FWIKYRLRLLNACRVSESHSMLLWGALAGFVGALATIAFRECIALLQIWMTGHDGSFVDI 63 +W++ RL H +L L G GALATIAFREC+ LQ W+ G D V Sbjct: 17 WWVRAAARL----PFRREHLVLAIAGLIGCAGALATIAFRECLRQLQWWLAGADQGLVAT 72 Query: 64 AKGLPWYTRVLLPTCGGVVAGLFLVWA-KRTPAGNGGDYMEAVAIGDGAIPVRNTLLRSI 122 A+ LPW+ R+L+PT GG++AGL L + K P DYMEA+A+GDG + R +L+RS Sbjct: 73 ARALPWWARLLVPTAGGLLAGLTLQYGLKWIPRKGAEDYMEAIAVGDGVLSARQSLVRSA 132 Query: 123 SSLASIASGGSIGREGPMVQLSALCASLVGK-FSH-FPSS--RLRLLVACGAAAGITSAY 178 SSL S+ASG SIGREGPMVQL+A+C SL+G+ H P S +RLLVACGAAAGITSAY Sbjct: 133 SSLCSVASGASIGREGPMVQLAAMCGSLLGRVLRHAMPVSVEHMRLLVACGAAAGITSAY 192 Query: 179 NAPIAGAFFITEIVLGSLVMESFGPVVVASVVANITMRELPGYRAAYEMPYFPEIGGWEV 238 NAPIAGA F+ EIV G++ + GP++V++V A+I +R+ GY A Y MP+F + GWEV Sbjct: 193 NAPIAGAVFVCEIVFGAITTATLGPLLVSAVTADIIVRQFFGYGAVYAMPHFDFVSGWEV 252 Query: 239 MLFLVLGVLAGVLAPQFLRVLELGKHGFGKLRLPLPVRLGVGGLLVGLISVQVPEVWGNG 298 + +L LG+ AG+ P L +++ + F + RLP +RL +GGL+VG +S++VPEVWGNG Sbjct: 253 LTYLGLGLAAGMAGPLLLGLIDRARGAFARTRLPQALRLALGGLIVGALSIRVPEVWGNG 312 Query: 299 YSLVNSLLHTSWVWQAVLMVLVVKVLATSITVGSGAVGGIFTPTLFVGAAVGYLFGDAAQ 358 YS+VN LH W+WQ V +VLV KV AT+ + GSGAVGG+FTPTLF GAA+G L+G Sbjct: 313 YSVVNGFLHAPWLWQTVALVLVCKVGATAASAGSGAVGGVFTPTLFCGAALGLLYGTGMH 372 Query: 359 AVLPVHISQPFAYAMVGMGAFLAAASYAPLMAILMIFEMTLSYQVVLPLMLSCVVAYVVA 418 A+LP P +YA+VGMGA LAA ++APLM+ILMIFEMTLSYQVVLPLML+C+ YV A Sbjct: 373 ALLPGAAPVPVSYAVVGMGALLAATTHAPLMSILMIFEMTLSYQVVLPLMLACITGYVTA 432 Query: 419 RSVDGRSMYEITLKRHRDNEERL 441 + S+Y L R+RD+ RL Sbjct: 433 HATGAPSVYARALARNRDDTLRL 455 >YPO2270 [P] COG0038 Chloride channel protein EriC Ype Yersinia pestis Length = 431 Score = 249 bits (636), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 178/412 (43%), Positives = 250/412 (60%), Gaps = 26/412 (6%) Query: 32 GFVGALATIAFRECIALLQIWM--TGHDGSFVDIAKGLPWYTRVLLPTCGGVVAGLFLVW 89 G V AL F + + L+ W+ + DGS V A + + R L P GG+ A L+W Sbjct: 29 GMVSALIVWLFHQAMLGLE-WLLFSRTDGSLVAAAASITGWRRALTPALGGLAA-GLLLW 86 Query: 90 A-----KRTPAGNGGDYMEAVAIGDGAIPVRNTLLRSISSLASIASGGSIGREGPMVQLS 144 A R P+ DYMEA+ IGDG + V +L++S++SL ++SG +IGREG MV L+ Sbjct: 87 AYQRYQHRKPSAPT-DYMEAIEIGDGRLDVSASLVKSLASLLVVSSGSAIGREGAMVLLA 145 Query: 145 ALCASLVGKFSHFPSSRLRLLVACGAAAGITSAYNAPIAGAFFITEIVLGSLVMESFGPV 204 AL AS+ + P +L VACGAAAG+ SAY+AP+AG+ FI EI+ G+L++ S GPV Sbjct: 146 ALFASVFAQRYAKPK-EWKLWVACGAAAGMASAYHAPLAGSLFIAEILFGTLMLASLGPV 204 Query: 205 VVASVVANITMRELPG-YRAAYEMPYFPEIGGWEVMLFL--VLGVLAGVLAPQFLRVLEL 261 V+A+V A +T+ L G Y++ P W V FL +LG++AG P FL+ + Sbjct: 205 VIAAVSALLTINLLQGGQETLYQVQTLPS--PWPVQYFLMALLGLMAGFSGPLFLKAMAA 262 Query: 262 GKHGFGKLRLPLPVRLGVGGLLVGLISVQVPEVWGNGYSLVNSLLHTSWVWQAVLM---V 318 H F L L P++L +GG++VGL+S+ PEVWGNGYS+V SLL T VL+ + Sbjct: 263 SSHAFRSLNLLPPLQLALGGIIVGLLSLIFPEVWGNGYSVVQSLLTTP---PGVLLIGGI 319 Query: 319 LVVKVLATSITVGSGAVGGIFTPTLFVGAAVGYLFGD--AAQAVLPVHISQPFAYAMVGM 376 L+ K+LA + GSGA GG+FTPTLFVGAA+G L G + VL +I A+ GM Sbjct: 320 LICKLLAVLASSGSGAPGGVFTPTLFVGAALGMLCGQIFSLWPVLGDNIG--LLMALTGM 377 Query: 377 GAFLAAASYAPLMAILMIFEMTLSYQVVLPLMLSCVVAYVVARSVDGRSMYE 428 LAA ++AP+MA LM+ EMT Y ++ L+LSCV+A +AR + S+Y Sbjct: 378 ATLLAATTHAPIMAALMVCEMTGEYTLLPGLLLSCVIATTIARWLRPISVYR 429 >ynfJ [P] COG0038 Chloride channel protein EriC Eco Escherichia coli K12 Length = 438 Score = 202 bits (513), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 157/417 (37%), Positives = 241/417 (57%), Gaps = 11/417 (2%) Query: 25 LLWGALAGFVGALATIAFRECIALLQ-IWMTGHDGSFVDIAKGLPWYTRVLLPTCGGVVA 83 LL + G + A A FR + LL+ +++ GS V+ A L + R+L P GG+ A Sbjct: 25 LLIATVVGILAAFAVAGFRHAMLLLEWLFLNNDSGSLVNAATNLSPWRRLLTPALGGLAA 84 Query: 84 GLFLV-WAKRTPAGNGG--DYMEAVAIGDGAIPVRNTLLRSISSLASIASGGSIGREGPM 140 GL L+ W K T DYMEA+ DG +L++S++SL + SG +IGREG M Sbjct: 85 GLLLMGWQKFTQQRPHAPTDYMEALQT-DGQFDYAASLVKSLASLLVVTSGSAIGREGAM 143 Query: 141 VQLSALCASLVG-KFSHFPSSRLRLLVACGAAAGITSAYNAPIAGAFFITEIVLGSLVME 199 + L+AL AS +F+ P +L +ACGAAAG+ +AY AP+AG+ FI E++ G++++ Sbjct: 144 ILLAALAASCFAQRFT--PRQEWKLWIACGAAAGMAAAYRAPLAGSLFIAEVLFGTMMLA 201 Query: 200 SFGPVVVASVVANITMRELPGYRAA--YEMPYFPEIGGWEVMLFLVLGVLAGVLAPQFLR 257 S GPV++++VVA + + L + A Y + + + L + GVLAG+ P L Sbjct: 202 SLGPVIISAVVA-LLVSNLINHSDALLYNVQLSVTVQARDYALIISTGVLAGLCGPLLLT 260 Query: 258 VLELGKHGFGKLRLPLPVRLGVGGLLVGLISVQVPEVWGNGYSLVNSLLHTSWVWQAVLM 317 ++ GF L+L P +L +GGL+VGL+S+ P VWGNGYS V S L + + Sbjct: 261 LMNACHRGFVSLKLAPPWQLALGGLIVGLLSLFTPAVWGNGYSTVQSFLTAPPLLMIIAG 320 Query: 318 VLVVKVLATSITVGSGAVGGIFTPTLFVGAAVGYLFGDAAQAVLPVHISQPFAYAMVGMG 377 + + K+ A + GSGA GG+FTPTLF+G A+G L+G + P + GM Sbjct: 321 IFLCKLCAVLASSGSGAPGGVFTPTLFIGLAIGMLYGRSLGLWFPDGEEITLLLGLTGMA 380 Query: 378 AFLAAASYAPLMAILMIFEMTLSYQVVLPLMLSCVVAYVVARSVDGRSMYEITLKRH 434 LAA ++AP+M+ LMI EMT YQ++ L+++CV+A V++R++ S+Y +H Sbjct: 381 TLLAATTHAPIMSTLMICEMTGEYQLLPGLLIACVIASVISRTLHRDSIYRQHTAQH 437 >Z2583 [P] COG0038 Chloride channel protein EriC EcZ Escherichia coli O157:H7 EDL933 Length = 438 Score = 202 bits (513), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 156/416 (37%), Positives = 239/416 (57%), Gaps = 9/416 (2%) Query: 25 LLWGALAGFVGALATIAFRECIALLQ-IWMTGHDGSFVDIAKGLPWYTRVLLPTCGGVVA 83 LL + G + A A FR + LL+ +++ GS V+ A L + R+L P GG+ A Sbjct: 25 LLIATVVGILAAFAVAGFRHAMLLLEWLFLNNDSGSLVNAATNLSPWRRLLTPALGGLAA 84 Query: 84 GLFLV-WAKRTPAGNGG--DYMEAVAIGDGAIPVRNTLLRSISSLASIASGGSIGREGPM 140 GL L+ W K T DYMEA+ DG +L++S++SL + SG +IGREG M Sbjct: 85 GLLLMGWQKFTQQRPHAPTDYMEALQT-DGQFDYAASLVKSLASLLVVTSGSAIGREGAM 143 Query: 141 VQLSALCASLVGKFSHFPSSRLRLLVACGAAAGITSAYNAPIAGAFFITEIVLGSLVMES 200 + L+AL AS + P +L +ACGAAAG+ +AY AP+AG+ FI E++ G++++ S Sbjct: 144 ILLAALAASCFAQ-RFTPRQEWKLWIACGAAAGMAAAYRAPLAGSLFIAEVLFGTMMLAS 202 Query: 201 FGPVVVASVVANITMRELPGYRAA--YEMPYFPEIGGWEVMLFLVLGVLAGVLAPQFLRV 258 GPV++++VVA + + L + A Y + + + L + GVLAG+ P L + Sbjct: 203 LGPVIISAVVA-LLVSNLINHSDALLYSVQLSVTVQARDYALIISTGVLAGLCGPLLLTL 261 Query: 259 LELGKHGFGKLRLPLPVRLGVGGLLVGLISVQVPEVWGNGYSLVNSLLHTSWVWQAVLMV 318 + GF L+L P +L +GGL+VGL+S+ P VWGNGYS V S L + + + Sbjct: 262 MNACHRGFVSLKLAPPWQLALGGLIVGLLSLFTPAVWGNGYSTVQSFLTAPPLLMIIAGI 321 Query: 319 LVVKVLATSITVGSGAVGGIFTPTLFVGAAVGYLFGDAAQAVLPVHISQPFAYAMVGMGA 378 + K+ A + GSGA GG+FTPTLF+G A+G L+G + P + GM Sbjct: 322 FLCKLCAVLASSGSGAPGGVFTPTLFIGLAIGMLYGRSLGLWFPDGEEITLLLGLTGMAT 381 Query: 379 FLAAASYAPLMAILMIFEMTLSYQVVLPLMLSCVVAYVVARSVDGRSMYEITLKRH 434 LAA ++AP+M+ LMI EMT YQ++ L+++CV+A V++R++ S+Y +H Sbjct: 382 LLAATTHAPIMSTLMICEMTGEYQLLPGLLIACVIASVISRTLHRDSIYRQHTAQH 437 >ECs2298 [P] COG0038 Chloride channel protein EriC Ecs Escherichia coli O157:H7 Length = 438 Score = 202 bits (513), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 156/416 (37%), Positives = 239/416 (57%), Gaps = 9/416 (2%) Query: 25 LLWGALAGFVGALATIAFRECIALLQ-IWMTGHDGSFVDIAKGLPWYTRVLLPTCGGVVA 83 LL + G + A A FR + LL+ +++ GS V+ A L + R+L P GG+ A Sbjct: 25 LLIATVVGILAAFAVAGFRHAMLLLEWLFLNNDSGSLVNAATNLSPWRRLLTPALGGLAA 84 Query: 84 GLFLV-WAKRTPAGNGG--DYMEAVAIGDGAIPVRNTLLRSISSLASIASGGSIGREGPM 140 GL L+ W K T DYMEA+ DG +L++S++SL + SG +IGREG M Sbjct: 85 GLLLMGWQKFTQQRPHAPTDYMEALQT-DGQFDYAASLVKSLASLLVVTSGSAIGREGAM 143 Query: 141 VQLSALCASLVGKFSHFPSSRLRLLVACGAAAGITSAYNAPIAGAFFITEIVLGSLVMES 200 + L+AL AS + P +L +ACGAAAG+ +AY AP+AG+ FI E++ G++++ S Sbjct: 144 ILLAALAASCFAQ-RFTPRQEWKLWIACGAAAGMAAAYRAPLAGSLFIAEVLFGTMMLAS 202 Query: 201 FGPVVVASVVANITMRELPGYRAA--YEMPYFPEIGGWEVMLFLVLGVLAGVLAPQFLRV 258 GPV++++VVA + + L + A Y + + + L + GVLAG+ P L + Sbjct: 203 LGPVIISAVVA-LLVSNLINHSDALLYSVQLSVTVQARDYALIISTGVLAGLCGPLLLTL 261 Query: 259 LELGKHGFGKLRLPLPVRLGVGGLLVGLISVQVPEVWGNGYSLVNSLLHTSWVWQAVLMV 318 + GF L+L P +L +GGL+VGL+S+ P VWGNGYS V S L + + + Sbjct: 262 MNACHRGFVSLKLAPPWQLALGGLIVGLLSLFTPAVWGNGYSTVQSFLTAPPLLMIIAGI 321 Query: 319 LVVKVLATSITVGSGAVGGIFTPTLFVGAAVGYLFGDAAQAVLPVHISQPFAYAMVGMGA 378 + K+ A + GSGA GG+FTPTLF+G A+G L+G + P + GM Sbjct: 322 FLCKLCAVLASSGSGAPGGVFTPTLFIGLAIGMLYGRSLGLWFPDGEEITLLLGLTGMAT 381 Query: 379 FLAAASYAPLMAILMIFEMTLSYQVVLPLMLSCVVAYVVARSVDGRSMYEITLKRH 434 LAA ++AP+M+ LMI EMT YQ++ L+++CV+A V++R++ S+Y +H Sbjct: 382 LLAATTHAPIMSTLMICEMTGEYQLLPGLLIACVIASVISRTLHRDSIYRQHTAQH 437 >STM1490 [P] COG0038 Chloride channel protein EriC Sty Salmonella typhimurium LT2 Length = 429 Score = 200 bits (509), Expect = 7e-51, Method: Compositional matrix adjust. Identities = 163/416 (39%), Positives = 248/416 (59%), Gaps = 9/416 (2%) Query: 25 LLWGALAGFVGALATIAFRECIALLQ-IWMTGHDGSFVDIAKGLPWYTRVLLPTCGGVVA 83 LL L G + ALA AFR + LL+ I+++ GS V+ A+GL + R++ P GG+ A Sbjct: 17 LLIATLIGILAALAVAAFRHAMQLLEWIFLSNDTGSLVNAAEGLSPWRRLITPALGGLAA 76 Query: 84 GLFLV-WAKRTPAGNGG--DYMEAVAIGDGAIPVRNTLLRSISSLASIASGGSIGREGPM 140 GL L W K DYMEA+ DG V +L++S++SL + SG +IGREG M Sbjct: 77 GLLLWGWQKMNQQRPHAPTDYMEALQT-DGQFDVGASLVKSLASLLVVVSGSAIGREGAM 135 Query: 141 VQLSALC-ASLVGKFSHFPSSRLRLLVACGAAAGITSAYNAPIAGAFFITEIVLGSLVME 199 + L+AL +S +F+ P +L +A GAAAG+ AY+AP+AG+ FI EI+ G+L++ Sbjct: 136 ILLAALAASSFARRFT--PREEWKLWIASGAAAGMAGAYHAPLAGSLFIAEILFGTLMLA 193 Query: 200 SFGPVVVASVVANITMRELPGYRAA-YEMPYFPEIGGWEVMLFLVLGVLAGVLAPQFLRV 258 S GPVVV++VVA +T L G + Y + ++ E ++ + G++AG+ P + + Sbjct: 194 SLGPVVVSAVVALLTTHVLNGSDSLLYTVHLTVDLHAREYVMIVSTGLVAGLCGPLLMWL 253 Query: 259 LELGKHGFGKLRLPLPVRLGVGGLLVGLISVQVPEVWGNGYSLVNSLLHTSWVWQAVLMV 318 + + F +L+L P +L +GGL+VGL+S+ P VWGNGYS+V S L + ++ + + Sbjct: 254 MTASHNSFLRLKLSPPWQLALGGLIVGLLSLLTPTVWGNGYSVVQSFLLSPPLFSLIGGI 313 Query: 319 LVVKVLATSITVGSGAVGGIFTPTLFVGAAVGYLFGDAAQAVLPVHISQPFAYAMVGMGA 378 V K+LA + GSGA GG+FTPTLFVG ++G G LP + GM Sbjct: 314 FVCKILAVLASSGSGAPGGVFTPTLFVGLSIGMFLGRIWGFWLPGSDEIAILLGLAGMAT 373 Query: 379 FLAAASYAPLMAILMIFEMTLSYQVVLPLMLSCVVAYVVARSVDGRSMYEITLKRH 434 LAA ++AP+M+ LMI EMT YQ++ L+++CVVA V++R++ S+Y H Sbjct: 374 LLAATTHAPIMSTLMICEMTGEYQLLPGLLIACVVASVLSRTLRHDSIYRQHAAEH 429 >MA3609_1 [P] COG0038 Chloride channel protein EriC Mac Methanosarcina acetivorans str.C2A Length = 467 Score = 166 bits (421), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 136/368 (36%), Positives = 221/368 (60%), Gaps = 1/368 (0%) Query: 67 LPWYTRVLLPTCGGVVAGLFLVWAKRTPAGNGGDYMEAVAIGDGAIPVRNTLLRSISSLA 126 P Y +L+P GG++ GL + + G G +E V + I +R++ L +S+ Sbjct: 92 FPHYYVILMPALGGLLVGLISHFLIKKRYGVEG-LIETVTLRGARIKLRDSFLEVFASII 150 Query: 127 SIASGGSIGREGPMVQLSALCASLVGKFSHFPSSRLRLLVACGAAAGITSAYNAPIAGAF 186 +I+SGG++G+E P V A +LVG+ P +L+ L+ CGAA GI +A+NAP+AG Sbjct: 151 TISSGGALGKEAPGVLAGAGTGALVGRILKSPERQLQTLLGCGAAGGIAAAFNAPLAGVV 210 Query: 187 FITEIVLGSLVMESFGPVVVASVVANITMRELPGYRAAYEMPYFPEIGGWEVMLFLVLGV 246 F+ E++ G L ++F P+V++SV A + L G + PY E+ L+L+LG+ Sbjct: 211 FVVEVIYGELETKTFIPIVISSVFATLVSSTLFGIKPIQISPYQLISPYKELGLYLILGL 270 Query: 247 LAGVLAPQFLRVLELGKHGFGKLRLPLPVRLGVGGLLVGLISVQVPEVWGNGYSLVNSLL 306 LAG+++ +R L K F ++ L + +GGL VG+I + P V G GY+++ L Sbjct: 271 LAGLVSIMLIRTLYYTKDIFSEIPLHPVFKPALGGLAVGVIGLFYPRVLGMGYNVIMDAL 330 Query: 307 HTSWVWQAVLMVLVVKVLATSITVGSGAVGGIFTPTLFVGAAVGYLFGDAAQAVLPVHIS 366 + + +Q +L++L +K+LA S+++GSG GG P+LF GA +G FG AA + P I+ Sbjct: 331 NNEFTFQLLLILLFLKILAFSLSLGSGGSGGTIVPSLFAGAMLGGAFGTAANVLFPGTIA 390 Query: 367 QPFAYAMVGMGAFLAAASYAPLMAILMIFEMTLSYQVVLPLMLSCVVAYVVARSVDGRSM 426 + AYAMVGMGA A + APL AIL++FE+T Y ++LPLM +CV++ V++ ++ S+ Sbjct: 391 ESGAYAMVGMGAVFAGTARAPLTAILILFEITRDYSLILPLMFACVLSNVMSNAIYSESI 450 Query: 427 YEITLKRH 434 + L+R Sbjct: 451 FTEGLRRR 458 >AF1415_1 [P] COG0038 Chloride channel protein EriC Afu Archaeoglobus fulgidus Length = 450 Score = 145 bits (365), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 123/420 (29%), Positives = 208/420 (49%), Gaps = 21/420 (5%) Query: 20 ESHSMLLWGALAGFVGALATIAFRECIALL-QIWMTGHDGSFVDIAKGLPWYTRV----- 73 S ++L A+ G + L F + L +I+++G D +A G ++ Sbjct: 8 SSKYLILLAAIVGVISGLGAFIFYFLLDLFTKIFLSGLDSFNPPLAGGEAEVVKIELHLG 67 Query: 74 LLP-----TCGGVVAGLFLVWAKRTPAGNGGD-YMEAVAIGDGAIPVRNTLLRSISSLAS 127 +LP GG+++GL + G+G D + A G I R ++++I+S + Sbjct: 68 ILPLPVVVALGGLLSGLIVYKFAPEAEGHGTDAVIRAFHRARGEIRARVPIVKTIASAIT 127 Query: 128 IASGGSIGREGPMVQLSALCASLVGKFSHFPSSRLRLLVACGAAAGITSAYNAPIAGAFF 187 I SGGS GREGP+ Q+ A S VG+ R+LV CG A GI S + +P GA F Sbjct: 128 IGSGGSAGREGPIAQIGAGFGSFVGELLRLSDKDRRILVICGVAGGIGSIFRSPFGGAMF 187 Query: 188 ITEIVLG-SLVMESFGPVVVASVVANITMRELPGYRAA--------YEMPYFPEIGGWEV 238 E++ +E+ P V+S+VA I + Y A +++P E Sbjct: 188 GIEVLYKRDNEVEAIVPAFVSSIVAFIVFDVIMSYFANTPFGVLPIFKIPQVTIHSPLEF 247 Query: 239 MLFLVLGVLAGVLAPQFLRVLELGKHGFGKLRLPLPVRLGVGGLLVGLISVQVPEVWGNG 298 ++ ++ VLA +++V + ++ +P + +GG G+I + +P V G G Sbjct: 248 PIYAIVSVLAAFFGIIYVKVFYTVHNYSKRVSIPPYFKPAIGGFFTGVIGLFLPGVLGMG 307 Query: 299 YSLVNSLLHTSWVWQAVLMVLVVKVLATSITVGSGAVGGIFTPTLFVGAAVGYLFGDAAQ 358 Y V + +L+++ K++ATS+TVG+G GG+F P++ +G+ VG G + Sbjct: 308 YGYVQMAIDGKLAVTVMLLLIFGKIVATSLTVGTGGSGGVFAPSIVIGSMVGGFVGYSFH 367 Query: 359 AVLPVHISQPFAYAMVGMGAFLAAASYAPLMAILMIFEMTLSYQVVLPLMLSCVVAYVVA 418 + P I QP A+ ++GM AF+AA + P+ AILM+ EM Y ++ LM + +AY +A Sbjct: 368 YLFPNVIVQPEAFVLIGMSAFVAAVAKTPIAAILMVLEMCGGYSLLPALMTAATLAYYLA 427 >sll0855 [P] COG0038 Chloride channel protein EriC Syn Synechocystis Length = 451 Score = 143 bits (360), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 111/381 (29%), Positives = 190/381 (49%), Gaps = 10/381 (2%) Query: 67 LPWYTRVLLPTCGGVVAGLFLVWAKRTPAGNGGDYMEAVAIGDGAIPV---RNTLLRSIS 123 L W L+ GG+VA F + + P +G + +G +P+ R ++ + Sbjct: 73 LAWLVTALI--SGGMVALSFWLMKRFAPDTSGSGIPQIEGHLEGKLPLVWQRVLPIKLVG 130 Query: 124 SLASIASGGSIGREGPMVQLSALCASLVGKFSHFPSSRLRLLVACGAAAGITSAYNAPIA 183 S+ +G G EGP +Q+ + G + R+L+A GA AG+ +A+NAP+A Sbjct: 131 GFLSLGAGMLAGFEGPTIQMGGSIGQMTGGWFKATQENQRILIAVGAGAGLATAFNAPLA 190 Query: 184 GAFFITEIVLGSLVMES--FGPVVVASVVANITMRELPGYRAAYEMPYFPEIGGWEVMLF 241 G I E + ++ + ++ V+A I +R + G A + F + + +F Sbjct: 191 GVALIGEEMHPRFRSQTLAYHSLLFGCVMATIILRMIRGQSAIISLTEFKRVPLDSLWMF 250 Query: 242 LVLGVLAGVLAPQFLRVLELGKHGFGKLRLPLPVRLG--VGGLLVGLISVQVPEVWGNGY 299 ++LG+L GV+ F R L F +L PL + + G ++G++S+ + G Sbjct: 251 IILGILFGVMGYTFNRGLFKVLDWFDRLP-PLATKWKGFLLGSIIGILSLFPLPLTDGGD 309 Query: 300 SLVNSLLHTSWVWQAVLMVLVVKVLATSITVGSGAVGGIFTPTLFVGAAVGYLFGDAAQA 359 + V ++ + +++V + L T I GSGA+GGIF P L + + V Sbjct: 310 NAVLWAFNSQSHFSTLILVFCGRFLLTLICYGSGAIGGIFAPMLGIASIVSVAMARHFHL 369 Query: 360 VLPVHISQPFAYAMVGMGAFLAAASYAPLMAILMIFEMTLSYQVVLPLMLSCVVAYVVAR 419 + P I +P A+ GMGA +AA APL AIL+ EMT +Y V+LPL+++C+VA VVA Sbjct: 370 LFPSQIPEPAVMAIAGMGALVAATVRAPLTAILLTIEMTDNYFVILPLLVTCLVASVVAE 429 Query: 420 SVDGRSMYEITLKRHRDNEER 440 ++ G+ +Y + L+R + R Sbjct: 430 ALGGKPIYTVLLERTLAKQNR 450 >alr4891_1 [P] COG0038 Chloride channel protein EriC Nos Nostoc sp. PCC 7120 Length = 444 Score = 140 bits (354), Expect = 6e-33, Method: Compositional matrix adjust. Identities = 136/427 (31%), Positives = 217/427 (50%), Gaps = 37/427 (8%) Query: 32 GFVGALATIAFRECIALLQIWMTGHDGSFVDIAKGLPWYTRVLLPTCG---GVVAGLFLV 88 G + AL+ + + C LL W V + LP + V+LP G G +AGL + Sbjct: 22 GVLAALSAVFLKVCSGLLGAWR-------VHSSHILPAW--VVLPIIGLSFGYLAGLMVQ 72 Query: 89 WAKRTPAGNGGDYMEAVAIGDGAIPV----RNTLLRSISSLASIASGGSIGREGPMVQLS 144 AG+G ++A IP+ R +++ +S++ ++ SG ++GR+GP VQ+ Sbjct: 73 RLAPEAAGSGIPQVKATL---ANIPMKLSWRVAIVKLLSAILALGSGLTLGRQGPTVQVG 129 Query: 145 ALCASLVGKFSHFPSSRLRLLVACGAAAGITSAYNAPIAGAFFITEIVLGSLVMESFGPV 204 A A+ + + R ++A GA AG+ +A+NAPIAG FI E +L L + G Sbjct: 130 AGLAAGMSRLVPTSPDHRRQMIAAGAGAGLAAAFNAPIAGVLFIIEELLQDLSGLTLGTA 189 Query: 205 VVASVVANITMRELPGYRAAYEMPYFPEIGGW---EVMLFLVLGVLAGVLAPQFLRVLEL 261 ++AS + + R L G + G+ E+ FL+LGVLAG+L F R L Sbjct: 190 IIASFIGGVVSRLLGGRSLNLNIELLSYSSGFSFPEIPFFLLLGVLAGLLGALFNRGLIF 249 Query: 262 GKHGFGKLRLPLPVRLGVGGLLVGLISVQVPEVWGNGYSLVNSLLHTSWVWQAVLMVLVV 321 + L + LP+R+ + GL+ G++ +PE + + L ++ + + Sbjct: 250 SLQFYRNLHISLPLRVALAGLVSGIVVSLLPESFRDNAGLREYVITGDLNPSFAAIAFIA 309 Query: 322 KVLATSITVGSGAVGGIFTPTLFVGAAVGYLFGDAAQAVLPVHIS---QPFAYAMVGMGA 378 + + T + GSGA GG+F P+L +G+A+G+L G VL I+ P YA+ GMG Sbjct: 310 QFILTLVAFGSGAPGGLFAPSLILGSALGHLVG-----VLEYQITGDGSPVTYALAGMGG 364 Query: 379 FLAAASYAPLMAILMIFEMTLSYQVVLPLMLSCVVAYVVARSVDGRSMYE-------ITL 431 F +A S P+ AI+++FEMT + +VLPLM+ V AY+VA V S+YE ITL Sbjct: 365 FFSAVSKVPITAIVIVFEMTTDFNLVLPLMIVSVTAYLVADKVVPGSLYEKLLLLNGITL 424 Query: 432 KRHRDNE 438 + E Sbjct: 425 TKQMSVE 431