BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0147.p (405 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1171 [E] COG0527 Aspartokinases Rso Ralstonia solanacearum 649 0.0 NMA1701 [E] COG0527 Aspartokinases NmA Neisseria meningitidis Z2491 544 e-154 NMB1498 [E] COG0527 Aspartokinases Nme Neisseria meningitidis MC58 543 e-154 PA0904 [E] COG0527 Aspartokinases Pae Pseudomonas aeruginosa 515 e-146 mll3437 [E] COG0527 Aspartokinases Mlo Mesorhizobium loti 399 e-111 SMc02438 [E] COG0527 Aspartokinases Sme Sinorhizobium meliloti 394 e-109 AGl1357 [E] COG0527 Aspartokinases Atu Agrobacterium tumefaciens... 394 e-109 Cj0582 [E] COG0527 Aspartokinases Cje Campylobacter jejuni 392 e-109 BMEI0189 [E] COG0527 Aspartokinases Bme Brucella melitensis 390 e-108 CC0843 [E] COG0527 Aspartokinases Ccr Caulobacter vibrioides 389 e-108 >RSc1171 [E] COG0527 Aspartokinases Rso Ralstonia solanacearum Length = 416 Score = 649 bits (1675), Expect = 0.0, Method: Compositional matrix adjust. Identities = 333/404 (82%), Positives = 371/404 (91%) Query: 1 MGSIERIQNVAKRVAKWHDAGHQIVVVPSAMSGETNRLLGMAKEIMAQPDGRELDMLAST 60 MGS+ERI+NVAKRVAKWH AGHQIVVVPSAMSGETNRLLGMAKEI AQPD RELDM+AST Sbjct: 13 MGSVERIKNVAKRVAKWHRAGHQIVVVPSAMSGETNRLLGMAKEISAQPDPRELDMIAST 72 Query: 61 GEQVSVALLAIALQALGKQAVSYAGWQVPIKTDSAFTKARIRSIDDAKVRKDLNAGKIVI 120 GEQVSV LLAIAL A G A+SY GWQVP++TDSA+TKARI+SIDD +VR DL AG++V+ Sbjct: 73 GEQVSVGLLAIALHAEGIDAISYTGWQVPVQTDSAYTKARIQSIDDERVRADLEAGRVVV 132 Query: 121 ITGFQGVDADGNITTLGRGGSDTSAVAVAAAIKAAECLIYTDVDGVYTTDPRVVSEARRL 180 ITGFQG+D +G+ITTLGRGGSDTSAVAVAAA++A ECLIYTDVDGVYTTDPRVV +ARRL Sbjct: 133 ITGFQGIDGEGHITTLGRGGSDTSAVAVAAALEAEECLIYTDVDGVYTTDPRVVDDARRL 192 Query: 181 KTVTFEEMLEMASLGSKVLQIRSVEFAGNYKMPTRVLSSLTDPLTPLAEEAASGTLISFE 240 +TFEEMLEMASLGSKVLQIRSVEFAG Y++ TRVLSSLTDPL PL E SGTLI+FE Sbjct: 193 DKITFEEMLEMASLGSKVLQIRSVEFAGKYRVKTRVLSSLTDPLMPLEVEMHSGTLITFE 252 Query: 241 EDKNMEQATITGIAFSRDEAKITVLGVPDRPGIAYQILGPVADANIEVDMIIQNQSVEGK 300 ED NME A I+GIAF+RDEAKITV+GVPD+PGIAYQILGPVADANI+VDMIIQNQSV+GK Sbjct: 253 EDSNMEAAAISGIAFARDEAKITVIGVPDKPGIAYQILGPVADANIDVDMIIQNQSVDGK 312 Query: 301 TDFTFTVPRGEYAKAVEVLNNSVKAHIGAAAINGDTKVSKVSVVGVGMRSHVGIASQMFR 360 TDFTFTVPRG+Y +A+ +LN+SVK HIGAA ++GD KVSKVSVVGVGMRSHVGIAS+MFR Sbjct: 313 TDFTFTVPRGDYQRALGILNDSVKGHIGAANVSGDPKVSKVSVVGVGMRSHVGIASKMFR 372 Query: 361 TLSEEGVNIQMISTSEIKISVLIDEKYMELAVRALHKAFDLDSA 404 TLSEEG+NIQMISTSEIKISVLIDEKYMELAVRALHKAF+LD A Sbjct: 373 TLSEEGINIQMISTSEIKISVLIDEKYMELAVRALHKAFELDQA 416 >NMA1701 [E] COG0527 Aspartokinases NmA Neisseria meningitidis Z2491 Length = 405 Score = 544 bits (1402), Expect = e-154, Method: Compositional matrix adjust. Identities = 276/401 (68%), Positives = 332/401 (82%), Gaps = 9/401 (2%) Query: 1 MGSIERIQNVAKRVAKWHDAGHQIVVVPSAMSGETNRLLGMAKEIMAQPDGRELDMLAST 60 +GS ERI+NVAKRVAK GH IVVV SAMSGETNRL+ +A E+ PD RELD++ ST Sbjct: 13 VGSPERIKNVAKRVAKARAEGHDIVVVVSAMSGETNRLVALAHEMQEHPDPRELDVVLST 72 Query: 61 GEQVSVALLAIALQALGKQAVSYAGWQVPIKTDSAFTKARIRSIDDAKVRKDLNAGKIVI 120 GEQV++ LLA+AL+ +G A SY GWQV +KTD+A TKARI SIDD K+R DL AGK+VI Sbjct: 73 GEQVTIGLLAMALKDIGVDAKSYTGWQVALKTDTAHTKARIESIDDEKMRADLTAGKVVI 132 Query: 121 ITGFQGVDADGNITTLGRGGSDTSAVAVAAAIKAAECLIYTDVDGVYTTDPRVVSEARRL 180 + GFQG+ ++G+I+TLGRGGSDTSAVA+AAA+KA EC IYTDVDGVYTTDPRVV EARR+ Sbjct: 133 VAGFQGISSEGDISTLGRGGSDTSAVALAAALKADECQIYTDVDGVYTTDPRVVPEARRM 192 Query: 181 KTVTFEEMLEMASLGSKVLQIRSVEFAGNYKMPTRVLSSLTDPLTPLAEEAASGTLISFE 240 TVTFEEM+E+ASLGSKVLQIRSVEFAG YK+ RVLSSL D +GTLI+FE Sbjct: 193 DTVTFEEMIELASLGSKVLQIRSVEFAGKYKVRLRVLSSLQD--------GGNGTLITFE 244 Query: 241 EDKNMEQATITGIAFSRDEAKITVLGVPDRPGIAYQILGPVADANIEVDMIIQNQSVEGK 300 ED NME+A +TGIAF +++A+I V GVPD+PG+AYQILG VADANIEVDMIIQN EG Sbjct: 245 EDDNMERAAVTGIAFDKNQARINVRGVPDKPGVAYQILGAVADANIEVDMIIQNVGSEGT 304 Query: 301 TDFTFTVPRGEYAKAVEVLNNSVKAHIGAAAINGDTKVSKVSVVGVGMRSHVGIASQMFR 360 TDF+FTVPRG+Y + +E+L+ + IGAA+I+GD V KVS VG+GMRSHVG+A+++FR Sbjct: 305 TDFSFTVPRGDYKQTLEILSER-QDSIGAASIDGDDTVCKVSAVGLGMRSHVGVAAKIFR 363 Query: 361 TLSEEGVNIQMISTSEIKISVLIDEKYMELAVRALHKAFDL 401 TL+EEG+NIQMISTSEIK+SVLIDEKYMELA R LHKAF+L Sbjct: 364 TLAEEGINIQMISTSEIKVSVLIDEKYMELATRVLHKAFNL 404 >NMB1498 [E] COG0527 Aspartokinases Nme Neisseria meningitidis MC58 Length = 405 Score = 543 bits (1399), Expect = e-154, Method: Compositional matrix adjust. Identities = 275/401 (68%), Positives = 332/401 (82%), Gaps = 9/401 (2%) Query: 1 MGSIERIQNVAKRVAKWHDAGHQIVVVPSAMSGETNRLLGMAKEIMAQPDGRELDMLAST 60 +GS ERI+NVAKRVAK GH IVVV SAMSGETNRL+ +A E+ PD RELD++ +T Sbjct: 13 VGSPERIKNVAKRVAKARAEGHDIVVVVSAMSGETNRLVALAHEMQEHPDPRELDVVLAT 72 Query: 61 GEQVSVALLAIALQALGKQAVSYAGWQVPIKTDSAFTKARIRSIDDAKVRKDLNAGKIVI 120 GEQV++ LLA+AL+ +G A SY GWQV +KTD+A TKARI SIDD K+R DL AGK+VI Sbjct: 73 GEQVTIGLLAMALKDIGVDAKSYTGWQVALKTDTAHTKARIESIDDEKMRADLTAGKVVI 132 Query: 121 ITGFQGVDADGNITTLGRGGSDTSAVAVAAAIKAAECLIYTDVDGVYTTDPRVVSEARRL 180 + GFQG+ ++G+I+TLGRGGSDTSAVA+AAA+KA EC IYTDVDGVYTTDPRVV EARR+ Sbjct: 133 VAGFQGISSEGDISTLGRGGSDTSAVALAAALKADECQIYTDVDGVYTTDPRVVPEARRM 192 Query: 181 KTVTFEEMLEMASLGSKVLQIRSVEFAGNYKMPTRVLSSLTDPLTPLAEEAASGTLISFE 240 TVTFEEM+E+ASLGSKVLQIRSVEFAG YK+ RVLSSL D +GTLI+FE Sbjct: 193 DTVTFEEMIELASLGSKVLQIRSVEFAGKYKVRLRVLSSLQD--------GGNGTLITFE 244 Query: 241 EDKNMEQATITGIAFSRDEAKITVLGVPDRPGIAYQILGPVADANIEVDMIIQNQSVEGK 300 ED NME+A +TGIAF +++A+I V GVPD+PG+AYQILG VADANIEVDMIIQN EG Sbjct: 245 EDDNMERAAVTGIAFDKNQARINVRGVPDKPGVAYQILGAVADANIEVDMIIQNVGSEGT 304 Query: 301 TDFTFTVPRGEYAKAVEVLNNSVKAHIGAAAINGDTKVSKVSVVGVGMRSHVGIASQMFR 360 TDF+FTVPRG+Y + +E+L+ + IGAA+I+GD V KVS VG+GMRSHVG+A+++FR Sbjct: 305 TDFSFTVPRGDYKQTLEILSER-QDSIGAASIDGDDTVCKVSAVGLGMRSHVGVAAKIFR 363 Query: 361 TLSEEGVNIQMISTSEIKISVLIDEKYMELAVRALHKAFDL 401 TL+EEG+NIQMISTSEIK+SVLIDEKYMELA R LHKAF+L Sbjct: 364 TLAEEGINIQMISTSEIKVSVLIDEKYMELATRVLHKAFNL 404 >PA0904 [E] COG0527 Aspartokinases Pae Pseudomonas aeruginosa Length = 412 Score = 515 bits (1327), Expect = e-146, Method: Compositional matrix adjust. Identities = 254/404 (62%), Positives = 323/404 (79%), Gaps = 11/404 (2%) Query: 1 MGSIERIQNVAKRVAKWHDAGHQIVVVPSAMSGETNRLLGMAKEIMAQPDGRELDMLAST 60 +G++ERI+ VA++V K+ +AG +VVV SAMSGETNRL+G+A +IM QP RELD++ ST Sbjct: 13 VGTVERIEQVAEKVKKFREAGDDVVVVVSAMSGETNRLIGLANQIMEQPVPRELDVMVST 72 Query: 61 GEQVSVALLAIALQALGKQAVSYAGWQVPIKTDSAFTKARIRSIDDAKVRKDLNAGKIVI 120 GEQV++ALL++AL G AVSY G QV I TDSA TKARI IDD +R DL AG++V+ Sbjct: 73 GEQVTIALLSMALIKRGVPAVSYTGNQVRILTDSAHTKARILHIDDTHIRADLKAGRVVV 132 Query: 121 ITGFQGVDADGNITTLGRGGSDTSAVAVAAAIKAAECLIYTDVDGVYTTDPRVVSEARRL 180 + GFQGVD +GNITTLGRGGSDT+ VA+AAA+KA EC IYTDVDGVYTTDPRVV +ARRL Sbjct: 133 VAGFQGVDGNGNITTLGRGGSDTTGVALAAALKADECQIYTDVDGVYTTDPRVVPQARRL 192 Query: 181 KTVTFEEMLEMASLGSKVLQIRSVEFAGNYKMPTRVLSSLTDPLTPLAEEAASGTLISF- 239 +TFEEMLEMASLGSKVLQIR+VEFAG Y +P RVL S + GTLI+ Sbjct: 193 DKITFEEMLEMASLGSKVLQIRAVEFAGKYNVPLRVLHSF---------QEGPGTLITID 243 Query: 240 EEDKNMEQATITGIAFSRDEAKITVLGVPDRPGIAYQILGPVADANIEVDMIIQNQSVEG 299 +E+++MEQ I+GIAF+RDEAK+T+ GVPD PG+A++ILGP++ AN+EVDMI+QN + + Sbjct: 244 DEEESMEQPIISGIAFNRDEAKLTIRGVPDTPGVAFKILGPISAANVEVDMIVQNVAHDN 303 Query: 300 KTDFTFTVPRGEYAKAVEVLNNSVKAHIGAAAINGDTKVSKVSVVGVGMRSHVGIASQMF 359 TDFTFTV R +Y A+E+L + A+IGA GDT ++KVS+VGVGMRSH G+AS+MF Sbjct: 304 TTDFTFTVHRNDYLNALEILKQTA-ANIGAREAIGDTNIAKVSIVGVGMRSHAGVASRMF 362 Query: 360 RTLSEEGVNIQMISTSEIKISVLIDEKYMELAVRALHKAFDLDS 403 L++E +NIQMISTSEIK+SV+I+EKY+ELAVRALH AF+LD+ Sbjct: 363 EALAKESINIQMISTSEIKVSVVIEEKYLELAVRALHTAFELDA 406 >mll3437 [E] COG0527 Aspartokinases Mlo Mesorhizobium loti Length = 417 Score = 399 bits (1026), Expect = e-111, Method: Compositional matrix adjust. Identities = 217/402 (53%), Positives = 289/402 (71%), Gaps = 5/402 (1%) Query: 4 IERIQNVAKRVAKWHDAGHQIVVVPSAMSGETNRLLGMAKEIMAQPDGRELDMLASTGEQ 63 I RI+NVA+ V + DAGH++ VV SAM+G+TN L+G +E D RE D + ++GEQ Sbjct: 16 IARIRNVARHVKREVDAGHEVAVVVSAMAGKTNELVGWTREASPMHDAREYDAVVASGEQ 75 Query: 64 VSVALLAIALQALGKQAVSYAGWQVPIKTDSAFTKARIRSIDDAKVRKDLNAGKIVIITG 123 V+ LLAI LQ +G A S+ GWQ+PIKTD+A ARI ID A + K G++ +I G Sbjct: 76 VTAGLLAITLQNMGVHARSWQGWQIPIKTDNAHGAARILDIDGAFLIKRFGEGQVAVIAG 135 Query: 124 FQGVDADGNITTLGRGGSDTSAVAVAAAIKAAECLIYTDVDGVYTTDPRVVSEARRLKTV 183 FQG+ D I TLGRGGSDTSAVA+AAA+KA C IYTDVDGVYTTDPR+ +ARRL + Sbjct: 136 FQGIGPDNRIATLGRGGSDTSAVAIAAAVKADRCDIYTDVDGVYTTDPRIEPKARRLAKI 195 Query: 184 TFEEMLEMASLGSKVLQIRSVEFAGNYKMPTRVLSSLTDPLTPLAEEAAS--GTLISFEE 241 +FEEMLEMASLG+KVLQ+RSVE A +++ T V SS DP P + + GTLI +E Sbjct: 196 SFEEMLEMASLGAKVLQVRSVELAMVHRVRTFVRSSFDDPDAPGMGDLLNPPGTLIC-DE 254 Query: 242 DKNMEQATITGIAFSRDEAKITVLGVPDRPGIAYQILGPVADANIEVDMIIQNQSVEGK- 300 ++ +EQ +TGIA+++DEA+I++ V DRPG+A I GP+A+ANI VDMI+QN S +GK Sbjct: 255 EEIVEQQVVTGIAYAKDEAQISLRRVGDRPGVAAGIFGPLAEANINVDMIVQNISEDGKF 314 Query: 301 TDFTFTVPRGEYAKAVEVLNNSVKAHIGAAAINGDTKVSKVSVVGVGMRSHVGIASQMFR 360 TD TFTVP G+ KA+ VL+ +KA +G + + +SKVSV+G+GMRSH G+A+ F+ Sbjct: 315 TDMTFTVPSGDVDKALAVLDR-LKAEVGYDVVQSEAGMSKVSVIGIGMRSHAGVAATAFK 373 Query: 361 TLSEEGVNIQMISTSEIKISVLIDEKYMELAVRALHKAFDLD 402 L+++ +NI+ I+TSEIKIS+LID Y ELAVR LH + LD Sbjct: 374 ALADKAINIRAITTSEIKISILIDGPYTELAVRTLHSVYGLD 415 >SMc02438 [E] COG0527 Aspartokinases Sme Sinorhizobium meliloti Length = 424 Score = 394 bits (1013), Expect = e-109, Method: Compositional matrix adjust. Identities = 218/411 (53%), Positives = 293/411 (71%), Gaps = 12/411 (2%) Query: 4 IERIQNVAKRVAKWHDAGHQIVVVPSAMSGETNRLLGMAKEIMA-----QP--DGRELDM 56 + RI NVA+ V + DAGH++ VV SAMSG+TN L+G + + P D RE D Sbjct: 16 LNRIHNVARHVKREVDAGHEVAVVVSAMSGKTNELVGWVENMPKVAGSNAPFYDAREYDA 75 Query: 57 LASTGEQVSVALLAIALQALGKQAVSYAGWQVPIKTDSAFTKARIRSIDDAKVRKDLNAG 116 + ++GEQV+ LLAIALQ++G A S+ GWQ+PIKTD+A ARI ID A V + + G Sbjct: 76 VVASGEQVTSGLLAIALQSMGINARSWQGWQLPIKTDNAHGAARILEIDGADVIRRMGEG 135 Query: 117 KIVIITGFQGVDADGNITTLGRGGSDTSAVAVAAAIKAAECLIYTDVDGVYTTDPRVVSE 176 ++ ++ GFQG+ D + TLGRGGSDTSAVA+AAA+KA C IYTDVDGVYTTDPR+ + Sbjct: 136 QVAVVAGFQGLGPDNRLATLGRGGSDTSAVAIAAAVKADRCDIYTDVDGVYTTDPRIEPK 195 Query: 177 ARRLKTVTFEEMLEMASLGSKVLQIRSVEFAGNYKMPTRVLSSLTDPLTPLAEEAAS--G 234 ARRLK + FEEMLEMASLG+KVLQ+RSVE A +K+ T V SS DP P + + G Sbjct: 196 ARRLKKIAFEEMLEMASLGAKVLQVRSVELAMVHKVRTFVRSSFEDPDAPGMGDLMNPPG 255 Query: 235 TLISFEEDKNMEQATITGIAFSRDEAKITVLGVPDRPGIAYQILGPVADANIEVDMIIQN 294 TLI +ED+ +EQ +TGIA+++DEA+I++ + DRPG++ I GP+A+A+I VDMI+QN Sbjct: 256 TLIC-DEDEIVEQEVVTGIAYAKDEAQISLRRLADRPGVSAAIFGPLAEAHINVDMIVQN 314 Query: 295 QSVEG-KTDFTFTVPRGEYAKAVEVLNNSVKAHIGAAAINGDTKVSKVSVVGVGMRSHVG 353 S +G KTD TFTVP G+ KA+ VL ++ K IG I ++ + KVSV+G+GMRSH G Sbjct: 315 ISEDGSKTDMTFTVPSGDVDKALRVLGDN-KEKIGYDVIQSESGLVKVSVIGIGMRSHAG 373 Query: 354 IASQMFRTLSEEGVNIQMISTSEIKISVLIDEKYMELAVRALHKAFDLDSA 404 +A+ FR L+++G+NI+ I+TSEIKIS+LID Y ELAVR LH + LD + Sbjct: 374 VAASAFRALADKGINIKAITTSEIKISILIDGPYAELAVRTLHSVYGLDKS 424 >AGl1357 [E] COG0527 Aspartokinases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 431 Score = 394 bits (1012), Expect = e-109, Method: Compositional matrix adjust. Identities = 215/413 (52%), Positives = 292/413 (70%), Gaps = 13/413 (3%) Query: 3 SIERIQNVAKRVAKWHDAGHQIVVVPSAMSGETNRLLGMAKEIM--------AQPDGREL 54 ++ERI NVA+ V + DAGH++ VV SAMSG+TN L+ + + D RE Sbjct: 21 NLERIHNVARHVKREVDAGHEVAVVVSAMSGKTNELVDWVQNAAKVAGTNAASFYDAREY 80 Query: 55 DMLASTGEQVSVALLAIALQALGKQAVSYAGWQVPIKTDSAFTKARIRSIDDAKVRKDLN 114 D + ++GEQV+ LLAI LQ++G A S+ GWQ+PI+TD+A ARI ID + + + Sbjct: 81 DAVVASGEQVTSGLLAITLQSMGINARSWQGWQIPIRTDNAHGAARILEIDGSDIVHRMG 140 Query: 115 AGKIVIITGFQGVDADGNITTLGRGGSDTSAVAVAAAIKAAECLIYTDVDGVYTTDPRVV 174 G++ ++ GFQG+ D I TLGRGGSDTSAVA+AAA+KA C IYTDVDGVYTTDPR+ Sbjct: 141 EGQVAVVAGFQGIGPDNRIATLGRGGSDTSAVAIAAAVKADRCDIYTDVDGVYTTDPRIE 200 Query: 175 SEARRLKTVTFEEMLEMASLGSKVLQIRSVEFAGNYKMPTRVLSSLTDPLTPLAEEAAS- 233 +ARR+K + FEEMLEMASLG+KVLQ+RSVE A +K+ T V SS DP P + + Sbjct: 201 PKARRMKKIAFEEMLEMASLGAKVLQVRSVELAMVHKVRTFVRSSFEDPDAPGMGDLINP 260 Query: 234 -GTLISFEEDKNMEQATITGIAFSRDEAKITVLGVPDRPGIAYQILGPVADANIEVDMII 292 GTLI +ED+ +EQ +TGIA+++DEA+I++ V DRPG++ I GP+A+A+I VDMI+ Sbjct: 261 PGTLIC-DEDEIVEQEVVTGIAYAKDEAQISLRRVADRPGVSAAIFGPLAEAHINVDMIV 319 Query: 293 QNQSVEG-KTDFTFTVPRGEYAKAVEVLNNSVKAHIGAAAINGDTKVSKVSVVGVGMRSH 351 QN S +G +TD TFTVP G+ AKA+ VL+ + K IG +T ++KVSV+G+GMRSH Sbjct: 320 QNISEDGSRTDMTFTVPSGDVAKALRVLDEN-KGQIGFDVAQNETGLAKVSVIGIGMRSH 378 Query: 352 VGIASQMFRTLSEEGVNIQMISTSEIKISVLIDEKYMELAVRALHKAFDLDSA 404 G+A+ F+ L+E+ +NI+ I+TSEIKIS+LID Y ELAVR LH A+ LD A Sbjct: 379 AGVAASAFKALAEKNINIKAITTSEIKISILIDGAYAELAVRTLHSAYGLDKA 431 >Cj0582 [E] COG0527 Aspartokinases Cje Campylobacter jejuni Length = 400 Score = 392 bits (1007), Expect = e-109, Method: Compositional matrix adjust. Identities = 205/403 (50%), Positives = 284/403 (70%), Gaps = 16/403 (3%) Query: 1 MGSIERIQNVAKRVAKWHDAGHQIVVVPSAMSGETNRLLGMAKEIMAQPDGRELDMLAST 60 +G++ERI+ VA RV + G+Q+VVV SAMSG TN L+ A+ P+G+++DML S+ Sbjct: 12 VGTLERIEAVANRVIQSAQQGNQLVVVVSAMSGVTNTLIEQAEYFSKTPNGKDMDMLLSS 71 Query: 61 GEQVSVALLAIALQALGKQAVSYAGWQVPIKTDSAFTKARIRSIDDAKVRKDLNAGKIVI 120 GE+V+ ALL+IAL G A+S++G + I TDS FTKARI ID ++ +L GKIV+ Sbjct: 72 GERVTSALLSIALNEKGCPAISFSGRKAGIITDSVFTKARIHHIDTKAIKSELQNGKIVV 131 Query: 121 ITGFQGVDADGNITTLGRGGSDTSAVAVAAAIKAAECLIYTDVDGVYTTDPRVVSEARRL 180 I GFQGVD +GN+TTLGRGGSD SAVAVA A+ A C IYTDVDGVYTTDPR+ +A++L Sbjct: 132 IAGFQGVDEEGNVTTLGRGGSDLSAVAVAGALNADLCEIYTDVDGVYTTDPRIEPKAKKL 191 Query: 181 KTVTFEEMLEMASLGSKVLQIRSVEFAGNYKMPTRVLSSLTDPLTPLAEEAASGTLISFE 240 +++EEMLE+ASLG+KVLQ RSVE A + SS + GT+I+ E Sbjct: 192 DKISYEEMLELASLGAKVLQNRSVELAKKLNVNLVTRSSFNNN---------EGTMITKE 242 Query: 241 EDKNMEQATITGIAFSRDEAKITVLGVPDRPGIAYQILGPVADANIEVDMIIQNQSVEGK 300 + MEQA ++GIA +++A++T+ + D+PGIA +I +A+ NI VDMIIQN V+G Sbjct: 243 D--GMEQALVSGIALDKNQARVTLRNIEDKPGIAAEIFSVLANENINVDMIIQNVGVDGA 300 Query: 301 TDFTFTVPRGEYAKAVEVLNNSVKAHIGA-AAINGDTKVSKVSVVGVGMRSHVGIASQMF 359 T+ FTVP+ E +E+ N+++ + + I D+ V KVS+VGVGM+SH G+AS+ F Sbjct: 301 TNLGFTVPQNE----LELAKNAMQKILSSKTTIESDSAVLKVSIVGVGMKSHSGVASKAF 356 Query: 360 RTLSEEGVNIQMISTSEIKISVLIDEKYMELAVRALHKAFDLD 402 + L++EG+NI MISTSEIKIS+++ EKY ELAVRALH+ + LD Sbjct: 357 KALADEGINIGMISTSEIKISMIVHEKYGELAVRALHECYGLD 399 >BMEI0189 [E] COG0527 Aspartokinases Bme Brucella melitensis Length = 423 Score = 390 bits (1003), Expect = e-108, Method: Compositional matrix adjust. Identities = 213/409 (52%), Positives = 297/409 (72%), Gaps = 12/409 (2%) Query: 4 IERIQNVAKRVAKWHDAGHQIVVVPSAMSGETNRLLGMAKEI-----MAQP--DGRELDM 56 +ERI NVA+ V + +AG+Q+ VV SAMSG+TN L+ + + + P D RE D Sbjct: 16 LERIYNVARHVKREVEAGNQVAVVVSAMSGKTNELVDWVQNMPKVCGASSPFYDAREYDT 75 Query: 57 LASTGEQVSVALLAIALQALGKQAVSYAGWQVPIKTDSAFTKARIRSIDDAKVRKDLNAG 116 + ++GEQV+ LLAIALQ++G A S+ GWQ+PI+TD+A ARI+ ID +++ + + G Sbjct: 76 IVASGEQVTSGLLAIALQSIGVDARSWQGWQIPIQTDNAHGAARIQEIDGSQIIRRMEMG 135 Query: 117 KIVIITGFQGVDADGNITTLGRGGSDTSAVAVAAAIKAAECLIYTDVDGVYTTDPRVVSE 176 ++ ++ GFQG+ D + TLGRGGSDTSAVAVAAA+KA C IYTDVDGVYTTDPR+ + Sbjct: 136 QVAVVAGFQGIGPDNRVATLGRGGSDTSAVAVAAAVKADRCDIYTDVDGVYTTDPRIEPK 195 Query: 177 ARRLKTVTFEEMLEMASLGSKVLQIRSVEFAGNYKMPTRVLSSLTDPLTPLAEEAAS--G 234 ARRL ++FEEMLEMASLG+KVLQ+RSVE A +K+ T V SS TDP P + + G Sbjct: 196 ARRLPKISFEEMLEMASLGAKVLQVRSVELAMVHKVRTFVRSSFTDPDAPGMGDPINPPG 255 Query: 235 TLISFEEDKNMEQATITGIAFSRDEAKITVLGVPDRPGIAYQILGPVADANIEVDMIIQN 294 TLI +E++ +EQ +TGIAF++DEA+I++ V DRPG++ I GP+A+ +I VDMI+QN Sbjct: 256 TLIC-DEEEIVEQQVVTGIAFAKDEAQISLRRVADRPGVSAAIFGPLAEEHINVDMIVQN 314 Query: 295 QSVEG-KTDFTFTVPRGEYAKAVEVLNNSVKAHIGAAAINGDTKVSKVSVVGVGMRSHVG 353 S +G KTD TFT+P G+ KA++VL+ + K+ I I +T ++K+SV+G+GMRSH G Sbjct: 315 VSEDGSKTDMTFTIPTGDIDKALKVLDKA-KSEISFDNIQSETGLAKISVIGIGMRSHAG 373 Query: 354 IASQMFRTLSEEGVNIQMISTSEIKISVLIDEKYMELAVRALHKAFDLD 402 +A+ F+ L+E+G+NI+ I+TSEIKIS+LID Y ELAVR LH + LD Sbjct: 374 VAATAFKALAEKGINIRAITTSEIKISILIDGPYAELAVRTLHAVYGLD 422 >CC0843 [E] COG0527 Aspartokinases Ccr Caulobacter vibrioides Length = 415 Score = 389 bits (1000), Expect = e-108, Method: Compositional matrix adjust. Identities = 210/405 (51%), Positives = 283/405 (69%), Gaps = 13/405 (3%) Query: 4 IERIQNVAKRVAKWHDAGHQIVVVPSAMSGETNRLL----GMAKEIMAQPDGR-ELDMLA 58 +ERI+ VA+ VA G Q+ VV SAMSG+TN L+ G + P+ E D + Sbjct: 16 LERIRRVARLVAAEVATGKQVAVVVSAMSGKTNELVAWTDGAGRAAAGLPESDDEYDAVV 75 Query: 59 STGEQVSVALLAIALQALGKQAVSYAGWQVPIKTDSAFTKARIRSIDDAKVRKDLNAGKI 118 ++GEQV+ LLA+ L+ +G +A S+ GWQVPI TD A +ARI I + + G+I Sbjct: 76 ASGEQVTAGLLAMTLRNMGHKARSFLGWQVPILTDEAHGRARIEEIPPENLEECFANGEI 135 Query: 119 VIITGFQGVDADGNITTLGRGGSDTSAVAVAAAIKAAECLIYTDVDGVYTTDPRVVSEAR 178 +I GFQGV + ITTLGRGGSDTSAVA+AAA+K +C IYTDVDGVYTTDPR+ S+AR Sbjct: 136 AVIAGFQGVTPNRRITTLGRGGSDTSAVAIAAAVK-GDCDIYTDVDGVYTTDPRIESKAR 194 Query: 179 RLKTVTFEEMLEMASLGSKVLQIRSVEFAGNYKMPTRVLSSLTDPLTPLAEEAASGTLIS 238 RL +++EEMLEMASLG+KVLQ RSVE A +++P RVLSS +P E GT++ Sbjct: 195 RLAKISYEEMLEMASLGAKVLQTRSVEMAMAHRVPVRVLSSFVEP----GEAPGQGTIVC 250 Query: 239 FEEDKNMEQATITGIAFSRDEAKITVLGVPDRPGIAYQILGPVADANIEVDMIIQNQSVE 298 EE+ ME+ ++G+A+SRDEAKIT+LG+PD PG++ QI G +A+AN+ VDMI+Q+++ Sbjct: 251 DEEEI-MEKRIVSGVAYSRDEAKITLLGLPDHPGVSSQIFGRLAEANVNVDMIVQSRARS 309 Query: 299 GKT-DFTFTVPRGEYAKAVEVLNNSVKAHIGAAAINGDTKVSKVSVVGVGMRSHVGIASQ 357 T + FTV + + +AVE++ + K IG A+ + V+KVSV+GVGMRSH G+A Sbjct: 310 ADTANMEFTVGKRDATRAVEIVQAAQK-EIGFEAVAVNEDVAKVSVIGVGMRSHAGVAQS 368 Query: 358 MFRTLSEEGVNIQMISTSEIKISVLIDEKYMELAVRALHKAFDLD 402 MF+ L+E+ +NIQ+ISTSEIKISVLID Y ELAVRALH + LD Sbjct: 369 MFQALAEKNINIQVISTSEIKISVLIDAAYTELAVRALHAVYGLD 413