BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0143.p (239 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value HI0388 [O] COG1214 Inactive homolog of metal-dependent proteases... 157 2e-38 PA3685 [O] COG1214 Inactive homolog of metal-dependent proteases... 150 3e-36 RSc1367 [O] COG1214 Inactive homolog of metal-dependent protease... 150 3e-36 VC1989 [O] COG1214 Inactive homolog of metal-dependent proteases... 144 2e-34 YPO2072 [O] COG1214 Inactive homolog of metal-dependent protease... 141 2e-33 STM1820 [O] COG1214 Inactive homolog of metal-dependent protease... 139 8e-33 PM0709 [O] COG1214 Inactive homolog of metal-dependent proteases... 134 2e-31 ZyeaZ [O] COG1214 Inactive homolog of metal-dependent proteases,... 132 5e-31 ECs2516 [O] COG1214 Inactive homolog of metal-dependent protease... 132 5e-31 yeaZ [O] COG1214 Inactive homolog of metal-dependent proteases, ... 132 6e-31 >HI0388 [O] COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone Hin Haemophilus influenzae Length = 236 Score = 157 bits (396), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 94/231 (40%), Positives = 132/231 (57%), Gaps = 19/231 (8%) Query: 3 TILAIETSTELASAALLHQGKLLSRQSAGAQTHSDAILPMIQQLLAEAGLALAQCDALAF 62 T+LA++TSTE S ALL++G+ +TH+ ILPMI ++LA +GL L Q DALAF Sbjct: 5 TLLALDTSTEACSVALLYRGEKTHINELAQRTHTKRILPMIDEILANSGLGLNQVDALAF 64 Query: 63 GVGPGSFTGVRTACGVVQGLAFGVDRPVVPVVTLEAAAQAC-RVHDVQAAEVLAILDARM 121 G GPGSFTGVR G+ QGLAFG D PV+P+ L A AQA +H QA V+A +DARM Sbjct: 65 GRGPGSFTGVRVGAGIAQGLAFGADLPVIPISNLTAMAQAAFELH--QAENVVAAIDARM 122 Query: 122 GEVYWA---RYRPRGGGG----W-DVLAEPALSAAADVN--TQGRPYACGNGLSAYAEHF 171 EVY++ R + R G W ++++E S +N + G G +AY++ Sbjct: 123 NEVYFSQVVREKVRSDFGEFFQWREIISEQVCSPEQAINQLQNDNAFRVGTGWAAYSQFT 182 Query: 172 SPDFCGRQFAAAYASCMPHAQHVATLGQHHFDQGRGVPAQEAQPFYLRNKV 222 + G A +P+A ++ L Q + Q + A E +P YLRN+V Sbjct: 183 EKNLTGSDIA------LPNALYMLELAQVEYLQKHTISALEIEPIYLRNEV 227 >PA3685 [O] COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone Pae Pseudomonas aeruginosa Length = 226 Score = 150 bits (378), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 104/234 (44%), Positives = 137/234 (58%), Gaps = 25/234 (10%) Query: 1 MSTILAIETSTELASAALLHQGKLLSRQSAGAQTHSDAILPMIQQLLAEAGLALAQCDAL 60 MST+LA++TSTE S ALLH+G+ LS + H+ +LPM++ LL EAG+AL+ DA+ Sbjct: 1 MSTLLALDTSTEACSVALLHEGRALSHYEVIPRLHAQRLLPMVRDLLDEAGVALSAVDAI 60 Query: 61 AFGVGPGSFTGVRTACGVVQGLAFGVDRPVVPVVTLEAAAQACRVHDVQAAE-VLAILDA 119 AFG GPG+FTGVR A GVVQGLAF + RPV+ V L AQ R + Q AE V A +DA Sbjct: 61 AFGRGPGAFTGVRIAIGVVQGLAFALQRPVLAVSDLAILAQ--RAYREQGAERVAAAIDA 118 Query: 120 RMGEVYWARYRPRGG-----GGWDVL-----AEPALSAAADVNTQGRPYACGNGLSAYAE 169 RM EVYW Y+ + G G VL A P +AAAD + G G Y E Sbjct: 119 RMDEVYWGCYQLQQGEMRLAGSEAVLPPERVAVPWDAAAADW------FGAGTGWG-YVE 171 Query: 170 HFSPDFCGRQFAAAYASCMPHAQHVATLGQHHFDQGRGVPAQEAQPFYLRNKVA 223 ++ A AS +PHA+ + +L + +G GV A++A P YLR+ VA Sbjct: 172 RMP-----QRPVALDASLLPHAEDLLSLAGFAWARGEGVEAEQALPVYLRDNVA 220 >RSc1367 [O] COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone Rso Ralstonia solanacearum Length = 243 Score = 150 bits (378), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 98/232 (42%), Positives = 121/232 (52%), Gaps = 6/232 (2%) Query: 1 MSTILAIETSTELASAALLHQGKLLSRQSAGAQTHSDAILPMIQQLLAEAGLALAQCDAL 60 M ILA +TSTE S AL + L R S +LP +LLAEAG+AL C A+ Sbjct: 1 MPWILAFDTSTEFCSVALGDGTRTLFRHEHTGARSSSRVLPAAGELLAEAGIALGDCAAI 60 Query: 61 AFGVGPGSFTGVRTACGVVQGLAFGVDRPVVPVVTLEAAAQACRVHDVQAAEVLAILDAR 120 AFG GPGSFTG+RTACGV QGLAFG PVV V +L A A+ R V LDAR Sbjct: 61 AFGAGPGSFTGLRTACGVAQGLAFGAGLPVVQVNSLMACAEQTRAALPAGTAVTVALDAR 120 Query: 121 MGEVYWARYRP--RGGGGWDVLAEPALSAAADVNTQGRPY-ACGNGLSAYAEHFSPDFCG 177 M E YWA + P GW L+ +SA V +PY GN + + + + Sbjct: 121 MDECYWASFVPVAEDASGWHALSAVQVSAPQAVAPPQQPYWLAGNAAAVFGDRLA---AA 177 Query: 178 RQFAAAYASCMPHAQHVATLGQHHFDQGRGVPAQEAQPFYLRNKVALTTAER 229 AA PHA+ + TLG G V ++A P Y+R+KVALT ER Sbjct: 178 TGAAAVLPDVAPHAREIVTLGLRLLAAGHTVRPEDAAPLYVRDKVALTIEER 229 >VC1989 [O] COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone Vch Vibrio cholerae Length = 237 Score = 144 bits (363), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 93/232 (40%), Positives = 124/232 (53%), Gaps = 19/232 (8%) Query: 4 ILAIETSTELASAALLHQGKLLSRQSAGAQTHSDAILPMIQQLLAEAGLALAQCDALAFG 63 ILA++T+TE S ALL + SR + H+ +LPM+ ++L EAG+ L + DALAFG Sbjct: 5 ILALDTATERCSVALLVGNTVYSRSEIAPRDHTKKVLPMVDEVLKEAGVTLQELDALAFG 64 Query: 64 VGPGSFTGVRTACGVVQGLAFGVDRPVVPVVTLEAAAQAC-RVHDVQAAEVLAILDARMG 122 GPGSFTGVR G+ QGLAFG D P++ + TL A AQA R+ + V + +DARM Sbjct: 65 RGPGSFTGVRIGIGIAQGLAFGADLPMIGISTLAAMAQAAYRLQGL--THVASAIDARME 122 Query: 123 EVYWARYRPRGGGGWDV-----LAEPALSAAA----DVNTQGRPYAC-GNGLSAYAEHFS 172 EVYW RY + G W V + PAL A D+ + +A G G AY Sbjct: 123 EVYWGRYVRQEDGSWQVAEAECVIAPALLAQTLTQDDLTQDEQIWATAGTGWDAY----- 177 Query: 173 PDFCGRQFAAAYASCM-PHAQHVATLGQHHFDQGRGVPAQEAQPFYLRNKVA 223 P + + P AQ +A L Q QG V ++A P YLR+ VA Sbjct: 178 PALADLPLQLQTSEVLYPDAQDMAYLAQFELAQGNKVSVEQASPVYLRDTVA 229 >YPO2072 [O] COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone Ype Yersinia pestis Length = 232 Score = 141 bits (355), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 93/231 (40%), Positives = 125/231 (54%), Gaps = 16/231 (6%) Query: 1 MST-ILAIETSTELASAALLHQGKLLSRQSAGAQTHSDAILPMIQQLLAEAGLALAQCDA 59 MST ILAI+T+TE S AL + G++ + + H+ ILPM+QQ+LA +GL+L Q DA Sbjct: 1 MSTRILAIDTATEACSVALWNNGEVQALFELCPREHTQRILPMVQQILASSGLSLQQLDA 60 Query: 60 LAFGVGPGSFTGVRTACGVVQGLAFGVDRPVVPVVTLEAAAQ-ACRVHDVQAAEVLAILD 118 LAFG GPGSFTGVR G+ QGLA G + P++ V TL+ AQ A R+ A VLA +D Sbjct: 61 LAFGRGPGSFTGVRIGIGIGQGLALGANLPMIGVSTLQTMAQGAFRL--TGATRVLAAID 118 Query: 119 ARMGEVYWARYRPRGGGGW-----DVLAEPALSAAADVNTQGRPYACGNGLSAYAEHFSP 173 ARMGEVYW + G W + + PA + G G G Y P Sbjct: 119 ARMGEVYWGEFERNAEGHWLGEHTEAVMTPAQTLVRAEALSGHWATVGTGWQTY-----P 173 Query: 174 DFC-GRQFAAAYAS-CMPHAQHVATLGQHHFDQGRGVPAQEAQPFYLRNKV 222 D G A +P A+ + L + +G V ++A+P YLRN+V Sbjct: 174 DLVSGSDIALVDGQMSLPQAEDMLPLALSSWARGDAVKVEQAEPVYLRNEV 224 >STM1820 [O] COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone Sty Salmonella typhimurium LT2 Length = 231 Score = 139 bits (349), Expect = 8e-33, Method: Compositional matrix adjust. Identities = 88/228 (38%), Positives = 118/228 (51%), Gaps = 15/228 (6%) Query: 4 ILAIETSTELASAALLHQGKLLSRQSAGAQTHSDAILPMIQQLLAEAGLALAQCDALAFG 63 ILAI+T+TE S AL + G + + + H+ ILPM+Q++LA +G +L + DALAFG Sbjct: 3 ILAIDTATEACSVALWNNGTINAHFELCPREHTQRILPMVQEILAASGASLNEIDALAFG 62 Query: 64 VGPGSFTGVRTACGVVQGLAFGVDRPVVPVVTLEAAAQACRVHDVQAAEVLAILDARMGE 123 GPGSFTGVR G+ QGLA G + P++ V TL AQ A VLA +DARMGE Sbjct: 63 RGPGSFTGVRIGIGIAQGLALGANLPMIGVSTLATMAQGAW-RKTGATRVLAAIDARMGE 121 Query: 124 VYWARYRPRGGGGW-----DVLAEPALSAAADVNTQGRPYACGNGLSAYAEHFSPDF--- 175 VYWA Y+ G W + + +P G G G SA+ PD Sbjct: 122 VYWAEYQRDAQGVWQGEETEAVLKPERVGERLKQLSGEWATVGTGWSAW-----PDLAKE 176 Query: 176 CGRQFAAAYASCMPHAQHVATLGQHHFDQGRGVPAQEAQPFYLRNKVA 223 CG S +P A+ + + G V + A+P YLRN+VA Sbjct: 177 CGLTLHDGEVS-LPAAEDMLPIASQKLAAGETVAVEHAEPVYLRNEVA 223 >PM0709 [O] COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone Pmu Pasteurella multocida Length = 239 Score = 134 bits (337), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 87/232 (37%), Positives = 121/232 (52%), Gaps = 18/232 (7%) Query: 3 TILAIETSTELASAALLHQGKLLSRQSAGAQTHSDAILPMIQQLLAEAGLALAQCDALAF 62 T+LA++TSTE S ALL++G+ +TH+ ILPMI ++L ++GL+L Q DALAF Sbjct: 5 TLLALDTSTEACSVALLYKGEKTYLDELAQRTHTQRILPMIDEILCQSGLSLKQVDALAF 64 Query: 63 GVGPGSFTGVRTACGVVQGLAFGVDRPVVPVVTLEAAAQACRVHDVQAAEVLAILDARMG 122 G GPGSFTGVR G+ QGLA G D PV+P+ L AQA A VLA +DARM Sbjct: 65 GRGPGSFTGVRVGAGIAQGLALGADLPVIPISNLTMMAQAAY-EQFGAEHVLAAIDARMN 123 Query: 123 EVYWARYRPRGGG-------GWDVLAE-----PALSAAADVNTQGRPYACGNGLSAYAEH 170 EVY+++ + W V+ + P A G G G SAY + Sbjct: 124 EVYFSQLIAQAKQVGTDTLIDWQVIGQEKVVNPECLIAELAGLTGNWTTVGTGWSAYPQ- 182 Query: 171 FSPDFCGRQFAAAYASCMPHAQHVATLGQHHFDQGRGVPAQEAQPFYLRNKV 222 + F G+ +P AQ++ + Q + + A +P YLRN+V Sbjct: 183 LATLFAGQ----TTDILLPSAQYMLAPALLKWQQQQTINALAIEPVYLRNEV 230 >ZyeaZ [O] COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone EcZ Escherichia coli O157:H7 EDL933 Length = 231 Score = 132 bits (333), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 83/228 (36%), Positives = 118/228 (51%), Gaps = 15/228 (6%) Query: 4 ILAIETSTELASAALLHQGKLLSRQSAGAQTHSDAILPMIQQLLAEAGLALAQCDALAFG 63 ILAI+T+TE S AL + G + + + H+ ILPM+Q +L +G +L +ALA+G Sbjct: 3 ILAIDTATEACSVALWNDGTVNAHFELCPREHTQRILPMVQDILTTSGTSLTDINALAYG 62 Query: 64 VGPGSFTGVRTACGVVQGLAFGVDRPVVPVVTLEAAAQACRVHDVQAAEVLAILDARMGE 123 GPGSFTGVR G+ QGLA G + P++ V TL AQ + A VL+ +DARMGE Sbjct: 63 RGPGSFTGVRIGIGIAQGLALGAELPMIGVSTLMTMAQGAWRKN-GATRVLSAIDARMGE 121 Query: 124 VYWARYRPRGGGGW-----DVLAEPALSAAADVNTQGRPYACGNGLSAYAEHFSPDFCGR 178 VYWA Y+ G W + + +P L G G G A+ PD G+ Sbjct: 122 VYWAEYQRDENGIWHGEETEAVLKPELVHERMQQLSGEWVTVGTGWQAW-----PDL-GK 175 Query: 179 QFAAAYAS---CMPHAQHVATLGQHHFDQGRGVPAQEAQPFYLRNKVA 223 + +P A+ + + F +G+ V + A+P YLRN VA Sbjct: 176 ESGLVLRDGEVLLPAAEDMLPIACQMFAEGKTVAVEHAEPVYLRNNVA 223 >ECs2516 [O] COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone Ecs Escherichia coli O157:H7 Length = 231 Score = 132 bits (333), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 83/228 (36%), Positives = 118/228 (51%), Gaps = 15/228 (6%) Query: 4 ILAIETSTELASAALLHQGKLLSRQSAGAQTHSDAILPMIQQLLAEAGLALAQCDALAFG 63 ILAI+T+TE S AL + G + + + H+ ILPM+Q +L +G +L +ALA+G Sbjct: 3 ILAIDTATEACSVALWNDGTVNAHFELCPREHTQRILPMVQDILTTSGTSLTDINALAYG 62 Query: 64 VGPGSFTGVRTACGVVQGLAFGVDRPVVPVVTLEAAAQACRVHDVQAAEVLAILDARMGE 123 GPGSFTGVR G+ QGLA G + P++ V TL AQ + A VL+ +DARMGE Sbjct: 63 RGPGSFTGVRIGIGIAQGLALGAELPMIGVSTLMTMAQGAWRKN-GATRVLSAIDARMGE 121 Query: 124 VYWARYRPRGGGGW-----DVLAEPALSAAADVNTQGRPYACGNGLSAYAEHFSPDFCGR 178 VYWA Y+ G W + + +P L G G G A+ PD G+ Sbjct: 122 VYWAEYQRDENGIWHGEETEAVLKPELVHERMQQLSGEWVTVGTGWQAW-----PDL-GK 175 Query: 179 QFAAAYAS---CMPHAQHVATLGQHHFDQGRGVPAQEAQPFYLRNKVA 223 + +P A+ + + F +G+ V + A+P YLRN VA Sbjct: 176 ESGLVLRDGEVLLPAAEDMLPIACQMFAEGKTVAVEHAEPVYLRNNVA 223 >yeaZ [O] COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone Eco Escherichia coli K12 Length = 231 Score = 132 bits (333), Expect = 6e-31, Method: Compositional matrix adjust. Identities = 83/228 (36%), Positives = 118/228 (51%), Gaps = 15/228 (6%) Query: 4 ILAIETSTELASAALLHQGKLLSRQSAGAQTHSDAILPMIQQLLAEAGLALAQCDALAFG 63 ILAI+T+TE S AL + G + + + H+ ILPM+Q +L +G +L +ALA+G Sbjct: 3 ILAIDTATEACSVALWNDGTVNAHFELCPREHTQRILPMVQDILTTSGTSLTDINALAYG 62 Query: 64 VGPGSFTGVRTACGVVQGLAFGVDRPVVPVVTLEAAAQACRVHDVQAAEVLAILDARMGE 123 GPGSFTGVR G+ QGLA G + P++ V TL AQ + A VLA +DARMGE Sbjct: 63 RGPGSFTGVRIGIGIAQGLALGAELPMIGVSTLMTMAQGAWRKN-GATRVLAAIDARMGE 121 Query: 124 VYWARYRPRGGGGW-----DVLAEPALSAAADVNTQGRPYACGNGLSAYAEHFSPDFCGR 178 VYWA Y+ G W + + +P + G G G A+ PD G+ Sbjct: 122 VYWAEYQRDENGIWHGEETEAVLKPEIVHERMQQLSGEWVTVGTGWQAW-----PDL-GK 175 Query: 179 QFAAAYAS---CMPHAQHVATLGQHHFDQGRGVPAQEAQPFYLRNKVA 223 + +P A+ + + F +G+ V + A+P YLRN VA Sbjct: 176 ESGLVLRDGEVLLPAAEDMLPIACQMFAEGKTVAVEHAEPVYLRNNVA 223