BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0119.p (684 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ECs3283 [L] COG0272 NAD-dependent DNA ligase (contains BRCT doma... 756 0.0 lig [L] COG0272 NAD-dependent DNA ligase (contains BRCT domain t... 753 0.0 Zlig [L] COG0272 NAD-dependent DNA ligase (contains BRCT domain ... 752 0.0 YPO2989 [L] COG0272 NAD-dependent DNA ligase (contains BRCT doma... 749 0.0 VC0971 [L] COG0272 NAD-dependent DNA ligase (contains BRCT domai... 748 0.0 HI1100 [L] COG0272 NAD-dependent DNA ligase (contains BRCT domai... 743 0.0 STM2427 [L] COG0272 NAD-dependent DNA ligase (contains BRCT doma... 742 0.0 PM1716 [L] COG0272 NAD-dependent DNA ligase (contains BRCT domai... 738 0.0 RSc1398 [L] COG0272 NAD-dependent DNA ligase (contains BRCT doma... 661 0.0 NMA0865 [L] COG0272 NAD-dependent DNA ligase (contains BRCT doma... 639 0.0 >ECs3283 [L] COG0272 NAD-dependent DNA ligase (contains BRCT domain type II) Ecs Escherichia coli O157:H7 Length = 671 Score = 756 bits (1951), Expect = 0.0, Method: Compositional matrix adjust. Identities = 375/653 (57%), Positives = 482/653 (73%), Gaps = 3/653 (0%) Query: 21 LRADLNRHNYSYYVLDQPSIPDAEYDRLFQELQALETAHPELLTPDSPTQRVGAGPLPQF 80 LR L H Y Y+V+D P IPDAEYDRL +EL+ LET HPEL+TPDSPTQRVGA PL F Sbjct: 11 LRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRELETKHPELITPDSPTQRVGAAPLAAF 70 Query: 81 EPVRHDIPMLSLGNGFSDDDIEAFDKRVRDGLETLQEVRYATELKFDGLAISLRYENGVL 140 +RH++PMLSL N F ++ AF+KRV+D L++ ++V + ELK DGLA+S+ YENGVL Sbjct: 71 SQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKSNEKVTWCCELKLDGLAVSILYENGVL 130 Query: 141 VQAATRGDGTTGENVTANIRTVRAIPLRLHGEAIPQLLDVRGEVLMYKDDFARLNQRQRD 200 V AATRGDGTTGE++T+N+RT+RAIPL+LHGE IP L+VRGEV + + F ++N+ R Sbjct: 131 VSAATRGDGTTGEDITSNVRTIRAIPLKLHGENIPARLEVRGEVFLPQAGFEKINEDARR 190 Query: 201 AGQKEFANPRNAAAGSLRQLDSRITAQRTLRFFAYGIGVLEGADMPSSHSALLDWYQQLG 260 G K FANPRNAAAGSLRQLD RITA+R L FF YG+GVLEG ++P +H L +++ G Sbjct: 191 TGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGVLEGGELPDTHLGRLLQFKKWG 250 Query: 261 LPVCKERAVVTGATGLLEFFRGIGAKRESLPYEIDGVVYKVDRLDQQKQLGFVSRAPRFA 320 LPV + A +L F+ + R +L ++IDGVV KV+ L+QQ+QLGFV+RAPR+A Sbjct: 251 LPVSDRVTLCESAEEVLAFYHKVEEDRPTLGFDIDGVVIKVNSLEQQEQLGFVARAPRWA 310 Query: 321 LAHKFPAQEALTVVQDIEVQVGRTGAITPVARLNPVFVGGVTVTNATLHNEDEVRRKDIQ 380 +A KFPAQE +T V+D+E QVGRTGAITPVARL PV V GV V+NATLHN DE+ R ++ Sbjct: 311 VAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVHVAGVLVSNATLHNADEIERLGLR 370 Query: 381 IGDTVIVRRAGDVIPEVVAYVPEKRPADARAFVMPAACPVCGSPIVRAEDEAVARCSGGW 440 IGD V++RRAGDVIP+VV V +RP D R V P CPVCGS + R E EAVARC+GG Sbjct: 371 IGDKVVIRRAGDVIPQVVNVVLSERPEDTREVVFPTYCPVCGSDVERVEGEAVARCTGG- 429 Query: 441 LKCSAQRKGGLQHFASRRAMDIEGLGEQLVEQLVDRKVVNTPADLYRLGLSALAELDRMA 500 L C AQRK L+HF SRRAMD++G+G+++++QLV+++ V+TPADL++L L L+RM Sbjct: 430 LICGAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEKEYVHTPADLFKLTAGKLTGLERMG 489 Query: 501 EKSAQNVLDALQKSKSTTLARFIYALGIRHVGEATAKELARHFGGLDKILAASEAQLLEV 560 KSAQNV++AL+K+K TT ARF+YALGIR VGEATA LA +FG L+ + AAS +L +V Sbjct: 490 PKSAQNVVNALEKAKETTFARFLYALGIREVGEATAAGLAAYFGTLEALEAASIEELQKV 549 Query: 561 ADVGPVVATSIRSFFDDALNVELVEQLRAVGVHWPESAGVEAAA--KHLAGKTFVLTGTL 618 DVG VVA+ + +FF + N ++ +L A GVHWP + A AGKT VLTG+L Sbjct: 550 PDVGIVVASHVHNFFAEESNRNVISELLAEGVHWPAPIVINAEEIDSPFAGKTVVLTGSL 609 Query: 619 PNLSRDEASQLIEAAGGKVTGSVSKKTTYVVAGAEAGSKLAKAEELGIAILDE 671 +SRD+A + G KV GSVSKKT V+AG AGSKLAKA+ELGI ++DE Sbjct: 610 SQMSRDDAKARLVELGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIEVIDE 662 >lig [L] COG0272 NAD-dependent DNA ligase (contains BRCT domain type II) Eco Escherichia coli K12 Length = 671 Score = 753 bits (1944), Expect = 0.0, Method: Compositional matrix adjust. Identities = 375/653 (57%), Positives = 480/653 (73%), Gaps = 3/653 (0%) Query: 21 LRADLNRHNYSYYVLDQPSIPDAEYDRLFQELQALETAHPELLTPDSPTQRVGAGPLPQF 80 LR L H Y Y+V+D P IPDAEYDRL +EL+ LET HPEL+TPDSPTQRVGA PL F Sbjct: 11 LRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRELETKHPELITPDSPTQRVGAAPLAAF 70 Query: 81 EPVRHDIPMLSLGNGFSDDDIEAFDKRVRDGLETLQEVRYATELKFDGLAISLRYENGVL 140 +RH++PMLSL N F ++ AF+KRV+D L+ ++V + ELK DGLA+S+ YENGVL Sbjct: 71 SQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKNNEKVTWCCELKLDGLAVSILYENGVL 130 Query: 141 VQAATRGDGTTGENVTANIRTVRAIPLRLHGEAIPQLLDVRGEVLMYKDDFARLNQRQRD 200 V AATRGDGTTGE++T+N+RT+RAIPL+LHGE IP L+VRGEV + + F ++N+ R Sbjct: 131 VSAATRGDGTTGEDITSNVRTIRAIPLKLHGENIPARLEVRGEVFLPQAGFEKINEDARR 190 Query: 201 AGQKEFANPRNAAAGSLRQLDSRITAQRTLRFFAYGIGVLEGADMPSSHSALLDWYQQLG 260 G K FANPRNAAAGSLRQLD RITA+R L FF YG+GVLEG ++P +H L +++ G Sbjct: 191 TGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGVLEGGELPDTHLGRLLQFKKWG 250 Query: 261 LPVCKERAVVTGATGLLEFFRGIGAKRESLPYEIDGVVYKVDRLDQQKQLGFVSRAPRFA 320 LPV + A +L F+ + R +L ++IDGVV KV+ L QQ+QLGFV+RAPR+A Sbjct: 251 LPVSDRVTLCESAEEVLAFYHKVEEDRPTLGFDIDGVVIKVNSLAQQEQLGFVARAPRWA 310 Query: 321 LAHKFPAQEALTVVQDIEVQVGRTGAITPVARLNPVFVGGVTVTNATLHNEDEVRRKDIQ 380 +A KFPAQE +T V+D+E QVGRTGAITPVARL PV V GV V+NATLHN DE+ R ++ Sbjct: 311 VAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVHVAGVLVSNATLHNADEIERLGLR 370 Query: 381 IGDTVIVRRAGDVIPEVVAYVPEKRPADARAFVMPAACPVCGSPIVRAEDEAVARCSGGW 440 IGD V++RRAGDVIP+VV V +RP D R V P CPVCGS + R E EAVARC+GG Sbjct: 371 IGDKVVIRRAGDVIPQVVNVVLSERPEDTREVVFPTHCPVCGSDVERVEGEAVARCTGG- 429 Query: 441 LKCSAQRKGGLQHFASRRAMDIEGLGEQLVEQLVDRKVVNTPADLYRLGLSALAELDRMA 500 L C AQRK L+HF SRRAMD++G+G+++++QLV+++ V+TPADL++L L L+RM Sbjct: 430 LICGAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEKEYVHTPADLFKLTAGKLTGLERMG 489 Query: 501 EKSAQNVLDALQKSKSTTLARFIYALGIRHVGEATAKELARHFGGLDKILAASEAQLLEV 560 KSAQNV++AL+K+K TT ARF+YALGIR VGEATA LA +FG L+ + AAS +L +V Sbjct: 490 PKSAQNVVNALEKAKETTFARFLYALGIREVGEATAAGLAAYFGTLEALEAASIEELQKV 549 Query: 561 ADVGPVVATSIRSFFDDALNVELVEQLRAVGVHWPESAGVEAAA--KHLAGKTFVLTGTL 618 DVG VVA+ + +FF + N ++ +L A GVHWP + A AGKT VLTG+L Sbjct: 550 PDVGIVVASHVHNFFAEESNRNVISELLAEGVHWPAPIVINAEEIDSPFAGKTVVLTGSL 609 Query: 619 PNLSRDEASQLIEAAGGKVTGSVSKKTTYVVAGAEAGSKLAKAEELGIAILDE 671 +SRD+A + G KV GSVSKKT V+AG AGSKLAKA+ELGI ++DE Sbjct: 610 SQMSRDDAKARLVELGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIEVIDE 662 >Zlig [L] COG0272 NAD-dependent DNA ligase (contains BRCT domain type II) EcZ Escherichia coli O157:H7 EDL933 Length = 671 Score = 752 bits (1941), Expect = 0.0, Method: Compositional matrix adjust. Identities = 375/653 (57%), Positives = 480/653 (73%), Gaps = 3/653 (0%) Query: 21 LRADLNRHNYSYYVLDQPSIPDAEYDRLFQELQALETAHPELLTPDSPTQRVGAGPLPQF 80 LR L H Y Y+V+D P IPDAEYDRL +EL+ LET HPEL+TPDSPTQRVGA PL F Sbjct: 11 LRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRELETKHPELITPDSPTQRVGAAPLAAF 70 Query: 81 EPVRHDIPMLSLGNGFSDDDIEAFDKRVRDGLETLQEVRYATELKFDGLAISLRYENGVL 140 +RH++PMLSL N F ++ AF+KRV+D L++ ++V + ELK DGLA+S+ YENGVL Sbjct: 71 SQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKSNEKVTWCCELKLDGLAVSILYENGVL 130 Query: 141 VQAATRGDGTTGENVTANIRTVRAIPLRLHGEAIPQLLDVRGEVLMYKDDFARLNQRQRD 200 V AATRGDGTTGE++T+N+RT+RAIPL+LHGE IP L+VRGEV + + F ++N+ R Sbjct: 131 VSAATRGDGTTGEDITSNVRTIRAIPLKLHGENIPARLEVRGEVFLPQAGFEKINEDARR 190 Query: 201 AGQKEFANPRNAAAGSLRQLDSRITAQRTLRFFAYGIGVLEGADMPSSHSALLDWYQQLG 260 G K FANPRNAAAGSLRQLD RITA+R L FF YG+GVLEG ++P +H L +++ G Sbjct: 191 TGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGVLEGGELPDTHLGRLLQFKKWG 250 Query: 261 LPVCKERAVVTGATGLLEFFRGIGAKRESLPYEIDGVVYKVDRLDQQKQLGFVSRAPRFA 320 LPV + A +L F+ R +L ++IDGVV KV+ L+QQ+QLGFV+RAPR+A Sbjct: 251 LPVSDRVTLCESAEEVLAFYXXXEEDRPTLGFDIDGVVIKVNSLEQQEQLGFVARAPRWA 310 Query: 321 LAHKFPAQEALTVVQDIEVQVGRTGAITPVARLNPVFVGGVTVTNATLHNEDEVRRKDIQ 380 +A KFPAQE +T V+D+E QVGRTGAITPVARL PV V GV V+NATLHN DE+ R ++ Sbjct: 311 VAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVHVAGVLVSNATLHNADEIERLGLR 370 Query: 381 IGDTVIVRRAGDVIPEVVAYVPEKRPADARAFVMPAACPVCGSPIVRAEDEAVARCSGGW 440 IGD V++RRAGDVIP+VV V +RP D R V P CPVCGS + R E EAVARC+GG Sbjct: 371 IGDKVVIRRAGDVIPQVVNVVLSERPEDTREVVFPTYCPVCGSDVERVEGEAVARCTGG- 429 Query: 441 LKCSAQRKGGLQHFASRRAMDIEGLGEQLVEQLVDRKVVNTPADLYRLGLSALAELDRMA 500 L C AQRK L+HF SRRAMD++G+G+++++QLV+++ V+TPADL++L L L+RM Sbjct: 430 LICGAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEKEYVHTPADLFKLTAGKLTGLERMG 489 Query: 501 EKSAQNVLDALQKSKSTTLARFIYALGIRHVGEATAKELARHFGGLDKILAASEAQLLEV 560 KSAQNV++AL+K+K TT ARF+YALGIR VGEATA LA +FG L+ + AAS +L +V Sbjct: 490 PKSAQNVVNALEKAKETTFARFLYALGIREVGEATAAGLAAYFGTLEALEAASIEELQKV 549 Query: 561 ADVGPVVATSIRSFFDDALNVELVEQLRAVGVHW--PESAGVEAAAKHLAGKTFVLTGTL 618 DVG VVA+ + +FF + N ++ +L A GVHW P E AGKT VLTG+L Sbjct: 550 PDVGIVVASHVHNFFAEESNRNVISELLAEGVHWXAPIVINAEEIDSPFAGKTVVLTGSL 609 Query: 619 PNLSRDEASQLIEAAGGKVTGSVSKKTTYVVAGAEAGSKLAKAEELGIAILDE 671 +SRD+A + G KV GSVSKKT V+AG AGSKLAKA+ELGI ++DE Sbjct: 610 SQMSRDDAKARLVELGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIEVIDE 662 >YPO2989 [L] COG0272 NAD-dependent DNA ligase (contains BRCT domain type II) Ype Yersinia pestis Length = 670 Score = 749 bits (1934), Expect = 0.0, Method: Compositional matrix adjust. Identities = 383/662 (57%), Positives = 480/662 (72%), Gaps = 4/662 (0%) Query: 21 LRADLNRHNYSYYVLDQPSIPDAEYDRLFQELQALETAHPELLTPDSPTQRVGAGPLPQF 80 LR L H + Y+VLD P IPDAEYDR+ Q+L+ LE HPEL+T DSPTQRVGA PL F Sbjct: 11 LRTSLRHHEHQYHVLDAPEIPDAEYDRMMQQLRDLEAQHPELVTNDSPTQRVGAAPLDAF 70 Query: 81 EPVRHDIPMLSLGNGFSDDDIEAFDKRVRDGLETLQEVRYATELKFDGLAISLRYENGVL 140 E V+H++PMLSL N F ++ AFDKRV D L+T + + + ELK DGLA+SL YENG L Sbjct: 71 EQVKHEVPMLSLDNVFDEESYLAFDKRVHDRLKTAEPLTFCCELKLDGLAVSLLYENGEL 130 Query: 141 VQAATRGDGTTGENVTANIRTVRAIPLRLHGEAIPQLLDVRGEVLMYKDDFARLNQRQRD 200 V+AATRGDGTTGEN+TAN+RT+RAIPLRLHG+ +P+ ++VRGEV M + F +LN+ R Sbjct: 131 VRAATRGDGTTGENITANVRTIRAIPLRLHGDNVPRRVEVRGEVFMPQAGFEQLNEEARR 190 Query: 201 AGQKEFANPRNAAAGSLRQLDSRITAQRTLRFFAYGIGVLEGADMPSSHSALLDWYQQLG 260 G K FANPRNAAAGSLRQLD RITA+R L FF YG+G+L+G ++P SH L ++ G Sbjct: 191 KGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGLLDGGELPRSHIQCLMQFKAWG 250 Query: 261 LPVCKERAVVTGATGLLEFFRGIGAKRESLPYEIDGVVYKVDRLDQQKQLGFVSRAPRFA 320 LPV + + TG+ ++ F+R I R L ++IDGVV KVD L Q+QLGFV+RAPR+A Sbjct: 251 LPVSERVKLCTGSDQVIAFYRQIEQDRAGLGFDIDGVVIKVDDLALQEQLGFVARAPRWA 310 Query: 321 LAHKFPAQEALTVVQDIEVQVGRTGAITPVARLNPVFVGGVTVTNATLHNEDEVRRKDIQ 380 A KFPAQE +T V+++E QVGRTGAITPVARL PV V GV V+NATLHN DE+ R ++ Sbjct: 311 TAFKFPAQEQITQVREVEFQVGRTGAITPVARLEPVQVAGVIVSNATLHNADEIERLGLR 370 Query: 381 IGDTVIVRRAGDVIPEVVAYVPEKRPADARAFVMPAACPVCGSPIVRAEDEAVARCSGGW 440 IGDTVIVRRAGDVIP+VV V E+RP D + P+ CPVCGS I R E EAVARC+GG Sbjct: 371 IGDTVIVRRAGDVIPQVVGVVMEQRPDDTKEITFPSQCPVCGSDIERVEGEAVARCTGG- 429 Query: 441 LKCSAQRKGGLQHFASRRAMDIEGLGEQLVEQLVDRKVVNTPADLYRLGLSALAELDRMA 500 L C+AQRK L+HF SRRA+D++G+G++++EQLV+++ V PADL++L L LDRM Sbjct: 430 LFCAAQRKEALKHFVSRRALDVDGMGDKIIEQLVEKQYVENPADLFQLTAGKLTGLDRMG 489 Query: 501 EKSAQNVLDALQKSKSTTLARFIYALGIRHVGEATAKELARHFGGLDKILAASEAQLLEV 560 KSAQN++ AL+K+K TT ARF+YALGIR VGEATA LA HF LD + AA L V Sbjct: 490 PKSAQNLIAALEKAKQTTFARFLYALGIREVGEATAANLAAHFRTLDNLRAADIETLKSV 549 Query: 561 ADVGPVVATSIRSFFDDALNVELVEQLRAVGVHWPESAG--VEAAAKHLAGKTFVLTGTL 618 DVG VVA + +F + N +++E+L V V WPE VE + AGKT VLTG+L Sbjct: 550 PDVGEVVAKHVMNFLSEEHNQKVIEELEKV-VSWPEPQQIVVEESDSPFAGKTVVLTGSL 608 Query: 619 PNLSRDEASQLIEAAGGKVTGSVSKKTTYVVAGAEAGSKLAKAEELGIAILDEDGLKALC 678 LSRDEA + A G KV+GSVSKKT V+AG AGSKLAKA+ELGI ++DE + L Sbjct: 609 TILSRDEAKDRLTALGAKVSGSVSKKTHLVIAGEAAGSKLAKAQELGIKVIDEAEMIRLL 668 Query: 679 AE 680 E Sbjct: 669 GE 670 >VC0971 [L] COG0272 NAD-dependent DNA ligase (contains BRCT domain type II) Vch Vibrio cholerae Length = 669 Score = 748 bits (1932), Expect = 0.0, Method: Compositional matrix adjust. Identities = 377/659 (57%), Positives = 476/659 (72%), Gaps = 2/659 (0%) Query: 17 RAFALRADLNRHNYSYYVLDQPSIPDAEYDRLFQELQALETAHPELLTPDSPTQRVGAGP 76 R LR L+ H YYV D PSIPDAEYDRL +EL LE AHPEL++ DSP+ RVG P Sbjct: 7 RLTELRKTLHEHGVRYYVEDAPSIPDAEYDRLMRELLELEAAHPELMSSDSPSLRVGGRP 66 Query: 77 LPQFEPVRHDIPMLSLGNGFSDDDIEAFDKRVRDGLETLQEVRYATELKFDGLAISLRYE 136 L FE V H+IPMLSL N F D ++E+F +R+ D + +Q + E K DGLA+SL YE Sbjct: 67 LDAFESVVHEIPMLSLDNAFDDGELESFYRRMTDRIPAVQHSAFCCEPKLDGLAVSLLYE 126 Query: 137 NGVLVQAATRGDGTTGENVTANIRTVRAIPLRLHGEAIPQLLDVRGEVLMYKDDFARLNQ 196 NGVL +AATRGDGTTGEN+T N+RT+++IPLRL G P L+VRGEV M K F LN Sbjct: 127 NGVLTRAATRGDGTTGENITENVRTIKSIPLRLQGADFPTRLEVRGEVFMPKAGFEALNA 186 Query: 197 RQRDAGQKEFANPRNAAAGSLRQLDSRITAQRTLRFFAYGIGVLEGADMPSSHSALLDWY 256 R G+K+F NPRNAAAGSLRQLDS+ITAQR L F+AY +GV+EG ++ +SH Sbjct: 187 RALKKGEKQFVNPRNAAAGSLRQLDSKITAQRPLAFYAYSVGVIEGGELATSHYQRFLQL 246 Query: 257 QQLGLPVCKERAVVTGATGLLEFFRGIGAKRESLPYEIDGVVYKVDRLDQQKQLGFVSRA 316 + GLP+C E +VT + F++ I +R+SL YEIDGVV KVD + Q++LGFV+RA Sbjct: 247 KGWGLPICPETKLVTSLAEVKAFYQDILQRRQSLAYEIDGVVIKVDDIQLQERLGFVARA 306 Query: 317 PRFALAHKFPAQEALTVVQDIEVQVGRTGAITPVARLNPVFVGGVTVTNATLHNEDEVRR 376 PR+A+A+KFPAQE LT++ D+E QVGRTGAITPVA+L PVFVGGVTV+NATLHN DE+ R Sbjct: 307 PRWAIAYKFPAQEELTLLNDVEFQVGRTGAITPVAKLEPVFVGGVTVSNATLHNADEIER 366 Query: 377 KDIQIGDTVIVRRAGDVIPEVVAYVPEKRPADARAFVMPAACPVCGSPIVRAEDEAVARC 436 + +GDTV++RRAGDVIP++V+ V E+RP +A++ V P CPVC S + R E EAVARC Sbjct: 367 LGVMVGDTVVIRRAGDVIPQIVSVVLERRPENAKSIVFPTRCPVCQSDVERVEGEAVARC 426 Query: 437 SGGWLKCSAQRKGGLQHFASRRAMDIEGLGEQLVEQLVDRKVVNTPADLYRLGLSALAEL 496 SGG L C AQRK L+HF SR+AMD+EGLG++++EQLVDR++V+TPADL+RL L L Sbjct: 427 SGG-LICQAQRKEALKHFVSRKAMDVEGLGDKVIEQLVDREMVSTPADLFRLRAGELTIL 485 Query: 497 DRMAEKSAQNVLDALQKSKSTTLARFIYALGIRHVGEATAKELARHFGGLDKILAASEAQ 556 +RM KSAQNV+DAL K+K TTL +F+YALGIR VGEATA LA+HF L+ I AS Q Sbjct: 486 ERMGPKSAQNVIDALNKAKQTTLPKFLYALGIREVGEATALNLAQHFLSLEAIQQASLEQ 545 Query: 557 LLEVADVGPVVATSIRSFFDDALNVELVEQLRAVGVHWPE-SAGVEAAAKHLAGKTFVLT 615 +EV DVG VVA+ +++FF N +++ +L G+ WP +A A LAGK VLT Sbjct: 546 FIEVPDVGVVVASHLQAFFAQDRNQQVINELLEQGITWPALTAAPVAVDSALAGKIVVLT 605 Query: 616 GTLPNLSRDEASQLIEAAGGKVTGSVSKKTTYVVAGAEAGSKLAKAEELGIAILDEDGL 674 G+ LSR++A ++A G KVTGSVSK T V AG AGSKLAKA ELGI + DE L Sbjct: 606 GSFTQLSRNDAKAALQALGAKVTGSVSKNTDMVFAGEAAGSKLAKATELGIQVFDEQAL 664 >HI1100 [L] COG0272 NAD-dependent DNA ligase (contains BRCT domain type II) Hin Haemophilus influenzae Length = 679 Score = 743 bits (1918), Expect = 0.0, Method: Compositional matrix adjust. Identities = 370/653 (56%), Positives = 476/653 (72%), Gaps = 2/653 (0%) Query: 21 LRADLNRHNYSYYVLDQPSIPDAEYDRLFQELQALETAHPELLTPDSPTQRVGAGPLPQF 80 LR L ++ Y Y+VLD PS+PD+EYDRLF +L+ALE HPE LT DSPTQRVGA PL F Sbjct: 20 LRKTLRQYEYEYHVLDNPSVPDSEYDRLFHQLKALELEHPEFLTSDSPTQRVGAKPLSGF 79 Query: 81 EPVRHDIPMLSLGNGFSDDDIEAFDKRVRDGLETL-QEVRYATELKFDGLAISLRYENGV 139 +RH+IPMLSL N FSD + AF KR+ D L L + + + E K DGLA+S+ Y NG Sbjct: 80 SQIRHEIPMLSLDNAFSDAEFNAFVKRIEDRLILLPKPLTFCCEPKLDGLAVSILYVNGE 139 Query: 140 LVQAATRGDGTTGENVTANIRTVRAIPLRLHGEAIPQLLDVRGEVLMYKDDFARLNQRQR 199 L QAATRGDGTTGE++TANIRT+R +PL+L + P L+VRGEV M F RLN+ Sbjct: 140 LTQAATRGDGTTGEDITANIRTIRNVPLQLLTDNPPARLEVRGEVFMPHAGFERLNKYAL 199 Query: 200 DAGQKEFANPRNAAAGSLRQLDSRITAQRTLRFFAYGIGVLEGADMPSSHSALLDWYQQL 259 + +K FANPRNAAAGSLRQLD IT++R L AYGIG+ EG D+P++H A L W + + Sbjct: 200 EHNEKTFANPRNAAAGSLRQLDPNITSKRPLVLNAYGIGIAEGVDLPTTHYARLQWLKSI 259 Query: 260 GLPVCKERAVVTGATGLLEFFRGIGAKRESLPYEIDGVVYKVDRLDQQKQLGFVSRAPRF 319 G+PV E + GA +L F+R I KR SL Y+IDG V K++ + Q +LGF+S+APR+ Sbjct: 260 GIPVNPEIRLCNGADEVLGFYRDIQNKRSSLGYDIDGTVLKINDIALQNELGFISKAPRW 319 Query: 320 ALAHKFPAQEALTVVQDIEVQVGRTGAITPVARLNPVFVGGVTVTNATLHNEDEVRRKDI 379 A+A+KFPAQE LT++ D+E QVGRTGAITPVA+L PVFV GVTV+NATLHN DE+ R +I Sbjct: 320 AIAYKFPAQEELTLLNDVEFQVGRTGAITPVAKLEPVFVAGVTVSNATLHNGDEIERLNI 379 Query: 380 QIGDTVIVRRAGDVIPEVVAYVPEKRPADARAFVMPAACPVCGSPIVRAEDEAVARCSGG 439 IGDTV++RRAGDVIP+++ + E+RP +A+ + P CPVC S I+R E EAVARC+GG Sbjct: 380 AIGDTVVIRRAGDVIPQIIGVLHERRPDNAKPIIFPTNCPVCDSQIIRIEGEAVARCTGG 439 Query: 440 WLKCSAQRKGGLQHFASRRAMDIEGLGEQLVEQLVDRKVVNTPADLYRLGLSALAELDRM 499 L C+AQRK L+HF SR+AMDI+G+G +L+EQLVDR++++TPADL++L L+ L L+RM Sbjct: 440 -LFCAAQRKEALKHFVSRKAMDIDGVGGKLIEQLVDRELIHTPADLFKLDLTTLTRLERM 498 Query: 500 AEKSAQNVLDALQKSKSTTLARFIYALGIRHVGEATAKELARHFGGLDKILAASEAQLLE 559 KSA+N L++L+ +KSTTLARFI+ALGIR VGEATA LA HF LD + A+ +L + Sbjct: 499 GAKSAENALNSLENAKSTTLARFIFALGIREVGEATALNLANHFKTLDALKDANLEELQQ 558 Query: 560 VADVGPVVATSIRSFFDDALNVELVEQLRAVGVHWPESAGVEAAAKHLAGKTFVLTGTLP 619 V DVG VVA I F+ +A NV +VE L A GVHW EA+ KT VLTGTL Sbjct: 559 VPDVGEVVANRIFIFWREAHNVAVVEDLIAQGVHWETVEVKEASENLFKDKTVVLTGTLT 618 Query: 620 NLSRDEASQLIEAAGGKVTGSVSKKTTYVVAGAEAGSKLAKAEELGIAILDED 672 + R+EA L++ G KV+GSVS KT +V+AG AGSKLAKA+EL I +L E+ Sbjct: 619 QMGRNEAKALLQQLGAKVSGSVSSKTDFVIAGDAAGSKLAKAQELNITVLTEE 671 >STM2427 [L] COG0272 NAD-dependent DNA ligase (contains BRCT domain type II) Sty Salmonella typhimurium LT2 Length = 671 Score = 742 bits (1915), Expect = 0.0, Method: Compositional matrix adjust. Identities = 371/653 (56%), Positives = 477/653 (73%), Gaps = 3/653 (0%) Query: 21 LRADLNRHNYSYYVLDQPSIPDAEYDRLFQELQALETAHPELLTPDSPTQRVGAGPLPQF 80 LR L H Y Y+V+D P IPDAEYDRL +EL+ LE P+L+TPDSPTQRVGA PL F Sbjct: 11 LRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRELEAQRPDLITPDSPTQRVGAAPLTAF 70 Query: 81 EPVRHDIPMLSLGNGFSDDDIEAFDKRVRDGLETLQEVRYATELKFDGLAISLRYENGVL 140 +RH++PMLSL N F ++ AF+KRV+D L++ + V + ELK DGLA+S+ YENGVL Sbjct: 71 NQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKSTENVIWCCELKLDGLAVSILYENGVL 130 Query: 141 VQAATRGDGTTGENVTANIRTVRAIPLRLHGEAIPQLLDVRGEVLMYKDDFARLNQRQRD 200 V AATRGDGTTGE++T+N+RT+RAIPL+LHG+ IP L+VRGEV + + F ++N+ R Sbjct: 131 VSAATRGDGTTGEDITSNVRTIRAIPLKLHGDNIPARLEVRGEVFLPQAGFEKINEDARR 190 Query: 201 AGQKEFANPRNAAAGSLRQLDSRITAQRTLRFFAYGIGVLEGADMPSSHSALLDWYQQLG 260 G K FANPRNAAAGSLRQLD RITA+R L FF YG+G+LEG ++P +H L ++ G Sbjct: 191 TGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGILEGGELPDTHLGRLLQFKAWG 250 Query: 261 LPVCKERAVVTGATGLLEFFRGIGAKRESLPYEIDGVVYKVDRLDQQKQLGFVSRAPRFA 320 LPV + +L+F+ + R +L ++IDGVV KV+ L Q+ LGFV+RAPR+A Sbjct: 251 LPVSDRVTLCDSPQAVLDFYHNVEKDRPTLGFDIDGVVIKVNSLALQELLGFVARAPRWA 310 Query: 321 LAHKFPAQEALTVVQDIEVQVGRTGAITPVARLNPVFVGGVTVTNATLHNEDEVRRKDIQ 380 +A KFPAQE +T V+D+E QVGRTGAITPVARL PV V GV V+NATLHN DE+ R ++ Sbjct: 311 VAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVQVAGVLVSNATLHNADEIERLGLR 370 Query: 381 IGDTVIVRRAGDVIPEVVAYVPEKRPADARAFVMPAACPVCGSPIVRAEDEAVARCSGGW 440 IGD V++RRAGDVIP+VV V +RP + R V P CPVCGS + R E EAV RC+GG Sbjct: 371 IGDKVVIRRAGDVIPQVVNVVLSERPEETRPIVFPTHCPVCGSDVERVEGEAVTRCTGG- 429 Query: 441 LKCSAQRKGGLQHFASRRAMDIEGLGEQLVEQLVDRKVVNTPADLYRLGLSALAELDRMA 500 L C AQRK L+HF SRRAMD++G+G+++++QLV+R+ V+TPADL+RL L LDRM Sbjct: 430 LICGAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEREYVHTPADLFRLTAGKLTGLDRMG 489 Query: 501 EKSAQNVLDALQKSKSTTLARFIYALGIRHVGEATAKELARHFGGLDKILAASEAQLLEV 560 KSAQNV++AL+KSK+TT ARF+YALGIR VGEATA LA +FG L+ + AA+ +L +V Sbjct: 490 PKSAQNVVNALEKSKTTTFARFLYALGIREVGEATAAGLAAYFGTLEALQAATIDELQKV 549 Query: 561 ADVGPVVATSIRSFFDDALNVELVEQLRAVGVHWPESA--GVEAAAKHLAGKTFVLTGTL 618 DVG VVAT + +FF + N +++ QL A GVHWP V+ AGKT VLTG+L Sbjct: 550 PDVGIVVATHVFNFFAEESNRDVIGQLLAEGVHWPAPVVINVQEIDSPFAGKTVVLTGSL 609 Query: 619 PNLSRDEASQLIEAAGGKVTGSVSKKTTYVVAGAEAGSKLAKAEELGIAILDE 671 +SRD+A + A G KV GSVSKKT V+AG AGSKLAKA+ELGI ++DE Sbjct: 610 SQMSRDDAKARLVALGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGITVIDE 662 >PM1716 [L] COG0272 NAD-dependent DNA ligase (contains BRCT domain type II) Pmu Pasteurella multocida Length = 673 Score = 738 bits (1905), Expect = 0.0, Method: Compositional matrix adjust. Identities = 374/657 (56%), Positives = 469/657 (71%), Gaps = 2/657 (0%) Query: 21 LRADLNRHNYSYYVLDQPSIPDAEYDRLFQELQALETAHPELLTPDSPTQRVGAGPLPQF 80 LR L H Y Y+VLD P IPDAEYDRLF L+ LE +P+ +PDSPTQRVGA PL F Sbjct: 12 LRQTLRYHEYQYHVLDNPQIPDAEYDRLFHRLKTLEQQYPQWFSPDSPTQRVGAKPLSAF 71 Query: 81 EPVRHDIPMLSLGNGFSDDDIEAFDKRVRDGLE-TLQEVRYATELKFDGLAISLRYENGV 139 V+H++PMLSL N FSD+++ AF KR++D L + + + + E K DGLA+S+ Y +G Sbjct: 72 AQVQHEMPMLSLDNAFSDEELHAFVKRIQDRLVFSPKLLEFCCEPKLDGLAVSILYVDGK 131 Query: 140 LVQAATRGDGTTGENVTANIRTVRAIPLRLHGEAIPQLLDVRGEVLMYKDDFARLNQRQR 199 L QAATRGDG+TGE++T NIRTVR IPL+L E P L+VRGEV M + F LN++ Sbjct: 132 LTQAATRGDGSTGEDITLNIRTVRNIPLQLLMENPPTRLEVRGEVFMSQAGFEVLNEKAL 191 Query: 200 DAGQKEFANPRNAAAGSLRQLDSRITAQRTLRFFAYGIGVLEGADMPSSHSALLDWYQQL 259 G+K FANPRNAAAGSLRQLD RIT+QR L AY IGV EG D+P +H L W + + Sbjct: 192 ARGEKTFANPRNAAAGSLRQLDPRITSQRPLLLNAYSIGVAEGIDLPDTHFERLQWLKSI 251 Query: 260 GLPVCKERAVVTGATGLLEFFRGIGAKRESLPYEIDGVVYKVDRLDQQKQLGFVSRAPRF 319 G+PV E + G +L F+R I KR +L Y+IDG V KV+ + Q++LGF+S+APR+ Sbjct: 252 GIPVNNEIQLCEGTENVLNFYRAIMQKRSTLGYDIDGTVIKVNDIALQEELGFISKAPRW 311 Query: 320 ALAHKFPAQEALTVVQDIEVQVGRTGAITPVARLNPVFVGGVTVTNATLHNEDEVRRKDI 379 A+A+KFPAQE LTV+ +E QVGRTGAITPVA+L PVFV GVTV+NATLHN DE+ R D+ Sbjct: 312 AIAYKFPAQEELTVLNAVEFQVGRTGAITPVAKLQPVFVAGVTVSNATLHNGDEIARLDV 371 Query: 380 QIGDTVIVRRAGDVIPEVVAYVPEKRPADARAFVMPAACPVCGSPIVRAEDEAVARCSGG 439 IGDTVI+RRAGDVIP+++ + EKRPA+A V P CPVCGS IVR E EAVARC+GG Sbjct: 372 AIGDTVIIRRAGDVIPQIIGVLHEKRPANAEKIVFPTECPVCGSVIVRIEGEAVARCTGG 431 Query: 440 WLKCSAQRKGGLQHFASRRAMDIEGLGEQLVEQLVDRKVVNTPADLYRLGLSALAELDRM 499 L C+AQRK L+HF SR+AMDI+G+G +L+EQLVDR+ ++TPADL++L L+ LA L+RM Sbjct: 432 -LFCAAQRKEALKHFVSRKAMDIDGVGAKLIEQLVDREQIHTPADLFKLDLNTLARLERM 490 Query: 500 AEKSAQNVLDALQKSKSTTLARFIYALGIRHVGEATAKELARHFGGLDKILAASEAQLLE 559 KSAQN LD+LQK+K TTLARFI+ALGIR VGEATA LA HF L+ + A+ QL E Sbjct: 491 GLKSAQNALDSLQKAKKTTLARFIFALGIREVGEATALNLANHFKTLEALKEATLEQLQE 550 Query: 560 VADVGPVVATSIRSFFDDALNVELVEQLRAVGVHWPESAGVEAAAKHLAGKTFVLTGTLP 619 V DVG VVA I F+ + NV +VE L A G+HW + KT VLTGTL Sbjct: 551 VQDVGEVVANRIFVFWREPHNVAVVEDLIAQGIHWETVEVKDVGDNPFKEKTVVLTGTLT 610 Query: 620 NLSRDEASQLIEAAGGKVTGSVSKKTTYVVAGAEAGSKLAKAEELGIAILDEDGLKA 676 + R EA L++ G KV+GSVS KT VVAG AGSKL KA ELG+ ++DE+ A Sbjct: 611 QMGRTEAKALLQQLGAKVSGSVSAKTDLVVAGDSAGSKLTKANELGVKVIDENTFLA 667 >RSc1398 [L] COG0272 NAD-dependent DNA ligase (contains BRCT domain type II) Rso Ralstonia solanacearum Length = 813 Score = 661 bits (1705), Expect = 0.0, Method: Compositional matrix adjust. Identities = 356/620 (57%), Positives = 432/620 (69%), Gaps = 47/620 (7%) Query: 16 VRAFALRADLNRHNYSYYVLDQPSIPDAEYDRLFQELQALETAHPELLTPDSPTQRVGAG 75 RA ALRA LNR+ + YYVLDQPS+PDAEYDRL++EL+ALE HPEL TPDSPT RVG Sbjct: 15 TRAAALRATLNRYAHEYYVLDQPSVPDAEYDRLYRELEALEAEHPELRTPDSPTLRVGGA 74 Query: 76 PLPQFEPVRHDIPMLSLGNGFSDDDIEA-----FDKRVRDGL---ETLQEVRYATELKFD 127 LP+F PVRH +PMLS+ ++ D A FD VR L E+ V YA ELKFD Sbjct: 75 VLPEFAPVRHVVPMLSI---RTETDTTAGGALDFDASVRRELGLAESDPPVEYAAELKFD 131 Query: 128 GLAISLRYENGVLVQAATRGDGTTGENVTANIRTVRAIPLRLH--GEAIPQLLDVRGEVL 185 GLAI+LRYE G LVQAATRGDG TGE+VT NIRT+R IPL L G A+P +L+VRGEV Sbjct: 132 GLAINLRYEKGFLVQAATRGDGATGEDVTQNIRTIRQIPLGLRPVGGAVPDVLEVRGEVY 191 Query: 186 MYKDDFARLNQRQRDAGQKEFANPRNAAAGSLRQLDSRITAQRTLRFFAYGIGVLEG-AD 244 M +DDF RLN RQR+ G K F NPRN AAG++RQLD ++ A+R L FFAYG+G G + Sbjct: 192 MRRDDFERLNARQRERGDKTFVNPRNTAAGAVRQLDPKMAAERPLSFFAYGLGEAAGWSG 251 Query: 245 MPSSHSALLDWYQQLGLPVCKERAVVTGATGLLEFFRGIGAKRESLPYEIDGVVYKVDRL 304 MP +HS +LD G PV KERA V G GL++F IGAKR+SLP++IDGVVYKV+ L Sbjct: 252 MPDTHSGMLDALVAYGFPVSKERAAVKGGEGLVQFHAAIGAKRDSLPFDIDGVVYKVNSL 311 Query: 305 DQQKQLGFVSRAPRFALAHKFPAQEALTVVQDIEVQVGRTGAITPVARLNPVFVGGVTVT 364 Q++LGF +R PR+A+AHK+PAQEALT V+ I VQVGRTGAITPVARL PVFVGGVTVT Sbjct: 312 ALQRELGFRTREPRWAVAHKYPAQEALTTVESIGVQVGRTGAITPVARLVPVFVGGVTVT 371 Query: 365 NATLHNEDEVRRKDIQIGDTVIVRRAGDVIPEVVAYVPEKRPAD---------------A 409 NATLHNEDEVRRKD+++GDTVIVRRAGDVIPEVVA V E+RP + Sbjct: 372 NATLHNEDEVRRKDVRVGDTVIVRRAGDVIPEVVAVVLERRPMEDVPGSDLFNPTQQPKH 431 Query: 410 RAFVMPAACPVCGSPIVRAEDEAVARCSGGWLKCSAQRKGGLQHFASRRAMDIEGLGEQL 469 F +P +CPVCGS +VR E EAVARCSGG L CSAQRK ++HFA RR MDIEGLGE+ Sbjct: 432 PPFELPRSCPVCGSHVVREEGEAVARCSGG-LFCSAQRKEAIRHFAGRRMMDIEGLGERY 490 Query: 470 VEQLVDRKVVNTPADLYRLGLSALAELDR-----------------MAEKSAQNVLDALQ 512 ++ LV+ + V+ ADLYRL L E+ R +A K A+N+LD ++ Sbjct: 491 IDNLVELEYVHGIADLYRLTLDDFLEMKRRADERDGVTPETVAAGKIATKWAENLLDGIR 550 Query: 513 KSKSTTLARFIYALGIRHVGEATAKELARHFGGLDKILAASEAQLLEVADVGPVVATSIR 572 SK+ LARF++A+GIRHVGE+TAK LA G L + A LL + DVG VA +I Sbjct: 551 ASKTPPLARFLFAMGIRHVGESTAKTLADWLGSLAIVRRAPAPLLLTLPDVGATVAEAIA 610 Query: 573 SFFDDALNVELVEQLRAVGV 592 FF + N + ++ L GV Sbjct: 611 DFFAEPKNQQALDALLTAGV 630 Score = 113 bits (282), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 90/215 (41%), Positives = 112/215 (52%), Gaps = 41/215 (19%) Query: 497 DRMAEKSAQNVLDAL---------QKSKSTTL------ARFIYALGIRHVGEATAKELAR 541 D AE Q LDAL + S L A ALG+ + +K+LA Sbjct: 611 DFFAEPKNQQALDALLTAGVAPQGEHPPSAKLRDQLEPAELYAALGVPKLTAIRSKQLAT 670 Query: 542 HFGGLDKILAASEAQLLEV-ADVGPVVATSIRSFFD-----------DALNVELVEQLRA 589 L ++ AQL + ADV A S+ ++ D DAL EL+ + Sbjct: 671 LVPSLAQLANVDTAQLEGLPADV----AASLLAWLDADDHRTRLGTLDALRAELLAAM-- 724 Query: 590 VGVHWPESAGVEAAAKHLAGKTFVLTGTLPNLSRDEASQLIEAAGGKVTGSVSKKTTYVV 649 P A E A L+GKT VLTGTLP LSRDEA ++EAAG KV+GSVSKKT YVV Sbjct: 725 -----PAGAAEEGA---LSGKTVVLTGTLPTLSRDEAKAMLEAAGAKVSGSVSKKTDYVV 776 Query: 650 AGAEAGSKLAKAEELGIAILDEDGLKALCAEPVAD 684 AG EAGSKLA+A+ELG+ +LDE G+ AL P D Sbjct: 777 AGVEAGSKLARAQELGVRVLDEAGMLALLQNPPGD 811 >NMA0865 [L] COG0272 NAD-dependent DNA ligase (contains BRCT domain type II) NmA Neisseria meningitidis Z2491 Length = 841 Score = 639 bits (1647), Expect = 0.0, Method: Compositional matrix adjust. Identities = 353/691 (51%), Positives = 443/691 (64%), Gaps = 75/691 (10%) Query: 25 LNRHNYSYYVLDQPSIPDAEYDRLFQELQALETAHPELLTPDSPTQRVGAGPLPQFEPVR 84 LNR+ Y YY LD PS+PDAEYD+LF+EL+ALE HPEL PDSPTQRVG PL F VR Sbjct: 37 LNRYAYEYYTLDAPSVPDAEYDKLFRELEALERNHPELKLPDSPTQRVGGEPLAGFAEVR 96 Query: 85 HDIPMLSLGNGFSDDD---------IEAFDKRVRDGLETLQEVRYATELKFDGLAISLRY 135 H++PMLSL N FS D + AFD+RVRDGL+ + Y E KFDGLAISL Y Sbjct: 97 HEVPMLSLTNAFSPQDENGVFDHAEMYAFDQRVRDGLDG-GKPEYVIEPKFDGLAISLLY 155 Query: 136 ENGVLVQAATRGDGTTGENVTANIRTVRAIPLRLHGEAIPQLLDVRGEVLMYKDDFARLN 195 +GVLVQAATRGDGTTGE+VT N++TV IPLRLHGE P+L++VRGEVLM K DFA LN Sbjct: 156 RDGVLVQAATRGDGTTGEDVTQNVKTVANIPLRLHGENTPELIEVRGEVLMLKADFAALN 215 Query: 196 QRQRDAGQKEFANPRNAAAGSLRQLDSRITAQRTLRFFAYGIGVLEGADMPSSHSALLDW 255 +RQ + GQK FANPRNAAAGSLRQLDSRITAQR L FF Y + +G + H L + Sbjct: 216 KRQAENGQKPFANPRNAAAGSLRQLDSRITAQRKLHFFPYSVARQQGGFVAEEHIQELAY 275 Query: 256 YQQLGLPVCKER-AVVTGATGLLEFFRGIGAKRESLPYEIDGVVYKVDRLDQQKQLGFVS 314 +Q LG + +L F+ + KR LPYEIDG+V KV+ L QQ++LGF+S Sbjct: 276 FQALGFSLPNGNFGCFKNIDEVLTFYEQMQQKRPELPYEIDGMVVKVNSLAQQRELGFIS 335 Query: 315 RAPRFALAHKFPAQEALTVVQDIEVQVGRTGAITPVARLNPVFVGGVTVTNATLHNEDEV 374 RAPR+A+AHKFPA+EALT+V+ I+VQ+GRTGA+TPVARL PVFVGGVTVTNATLHN+DEV Sbjct: 336 RAPRWAVAHKFPAEEALTIVEAIDVQIGRTGAVTPVARLQPVFVGGVTVTNATLHNQDEV 395 Query: 375 RRKDIQIGDTVIVRRAGDVIPEVVAYVPEKRPADARA----------------------- 411 RKD+++GDTV+VRRAGDVIPEVV + E+RP A Sbjct: 396 SRKDVRVGDTVVVRRAGDVIPEVVRVIFERRPMRETAVAVSDGIGHRQDDLFAETPSANQ 455 Query: 412 ---------FVMPAACPVCGSPIVRAEDEAVARCSGGWLKCSAQRKGGLQHFASRRAMDI 462 + +P CP+C S I R E EAVARCSGG L C AQR GL HFASR+AMDI Sbjct: 456 TQSVPLHKPYRLPTHCPICRSEIEREEGEAVARCSGGML-CQAQRAQGLIHFASRKAMDI 514 Query: 463 EGLGEQLVEQLVDRKVVNTPADLYRLGLSALAELDRMAEKS------------------- 503 +GLGE+ +EQLV + +V ADLYRL + L ++ A+K+ Sbjct: 515 DGLGEKQIEQLVAQDLVLHFADLYRLDIPTLQKMKETADKTVAESDQMPSEGSSVGASGK 574 Query: 504 --------AQNVLDALQKSKSTTLARFIYALGIRHVGEATAKELARHFGGLDKILAASEA 555 A+N+L ++ K+ LARF++ALGIRHVGE TAK LA+ FG L+++ A E Sbjct: 575 HKKQPVKWAENILAGIESGKTPELARFLFALGIRHVGERTAKTLAQAFGTLERVRRAPEP 634 Query: 556 QLLEVADVGPVVATSIRSFFDDALNVELVEQLRAVGVHWPESAGVEAAAKHLAGKTFVLT 615 L + D+G VVA SI FF A ++++L A GV A A+H + ++ Sbjct: 635 VLACLPDIGTVVARSIAHFFAQAEQQAMIDELLAAGVAPQTQAVTIPPARHAEPQRWI-- 692 Query: 616 GTLPN--LSRDEASQLIEAAGGKVTGSVSKK 644 LP+ +S ++A L E AG + G + K Sbjct: 693 ARLPDFKISENKAQALWELAGKNIEGLQNDK 723 Score = 102 bits (253), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 58/102 (56%), Positives = 67/102 (65%), Gaps = 4/102 (3%) Query: 580 NVELVEQLRAVGVHWPE----SAGVEAAAKHLAGKTFVLTGTLPNLSRDEASQLIEAAGG 635 N L+E L+ P + G + K +AGKTFVLTGTLP L RD+A LIEAAGG Sbjct: 738 NAALLENLKTFFAQMPSEDEAAQGSDGINKAVAGKTFVLTGTLPTLKRDQAQSLIEAAGG 797 Query: 636 KVTGSVSKKTTYVVAGAEAGSKLAKAEELGIAILDEDGLKAL 677 KV+GSVSKKT YVVAG AGSKL KA LG++IL E L L Sbjct: 798 KVSGSVSKKTDYVVAGEAAGSKLEKANALGVSILSEAELLTL 839