BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0116.p (857 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value all3879_1 [M] COG1181 D-alanine-D-alanine ligase and related ATP... 318 3e-86 slr2002_1 [M] COG1181 D-alanine-D-alanine ligase and related ATP... 304 5e-82 slr2002_2 [M] COG0769 UDP-N-acetylmuramyl tripeptide synthase Sy... 242 2e-63 all3879_2 [M] COG0769 UDP-N-acetylmuramyl tripeptide synthase No... 220 1e-56 alr0573 [M] COG1181 D-alanine-D-alanine ligase and related ATP-g... 209 2e-53 CAC1540 [M] COG1181 D-alanine-D-alanine ligase and related ATP-g... 187 8e-47 lin2913_2 [M] COG1181 D-alanine-D-alanine ligase and related ATP... 177 9e-44 BH3654_1 [M] COG1181 D-alanine-D-alanine ligase and related ATP-... 169 4e-41 PM1048_2 [M] COG1181 D-alanine-D-alanine ligase and related ATP-... 152 4e-36 BH3653_1 [M] COG1181 D-alanine-D-alanine ligase and related ATP-... 150 1e-35 >all3879_1 [M] COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes Nos Nostoc sp. PCC 7120 Length = 479 Score = 318 bits (816), Expect = 3e-86, Method: Compositional matrix adjust. Identities = 193/483 (39%), Positives = 273/483 (56%), Gaps = 26/483 (5%) Query: 1 MDVSRIRALRGPNLWS--RHTAI------EAIVSCPEDERVIDNMPGFELRLRARFPQI- 51 M + +I+ LRGPN WS RH I E + P +E +PGF L P + Sbjct: 1 MRILKIQTLRGPNYWSIRRHKLIVMRLDLETLAETPSNE-----IPGFYEGLVEALPSLE 55 Query: 52 -GFLEP--DGG-----KQVVSLAHALAAAALGLQSQAGCPVTFSRTVSTVETGIYQVVVE 103 + P GG ++ + H + AL LQ AG V F RT T GIYQVV+E Sbjct: 56 GHYCSPGCHGGFLMRVREGTMMGHIVEHVALELQELAGMHVGFGRTRETATPGIYQVVIE 115 Query: 104 YSEEEVGRLAFDLALELVRAAQADAPF---DLTAALTRIRELDEDVRLGPSTGSIVNAAI 160 Y EE GR A A+ L ++ + +L + +++L D LGPST +IV A Sbjct: 116 YLNEEAGRYAGRAAVRLCQSIVDRGRYPKAELEQDIQDLKDLWRDASLGPSTEAIVKEAE 175 Query: 161 KRGIPFRRLTQGSMVQFGWGSRQKRIQAAETSNTSAIAESIAQDKDLTKMLLHAAGVPVP 220 KRGIP+ +L+ ++Q G+G KR+QA T T + +A DK+ TK +L A+GVPVP Sbjct: 176 KRGIPWMQLSARFLIQLGYGVNHKRMQATMTDKTGILGVELACDKEATKRILAASGVPVP 235 Query: 221 NGRVVETVEDALKAAEEIGS-AVVIKPLDGNQGKGVAVNISTPEQITRAFNNAALISDEV 279 G V+ ++D +A E +G +VIKPLDGN G+G+ ++I + E+ A+ A +S + Sbjct: 236 RGTVINFLDDLEEAIEYVGGYPIVIKPLDGNHGRGITIDIRSWEEAEAAYEAARQVSRSI 295 Query: 280 IVERYLPGHDFRLLVIGKTLVAAARRDPPQVIGDGVHTIRQLIDQVNADPLRGDGHATSL 339 IVERY G D R+LV+ +VA A R P VIG+G T+ +LI+++N DP RGDGH L Sbjct: 296 IVERYYVGRDHRVLVVDGKVVAVAERVPAHVIGNGRSTVAELIEEINQDPNRGDGHDKVL 355 Query: 340 TKIRLDDIALSVLSGQNLDPEAIPAQGVRVVLRNNANLSTGGTATDVTDDVHPDVAARAI 399 TKI LD + +L ++P +G LR ANLSTGGTA D TD++HP+ A Sbjct: 356 TKIELDRTSYQLLERAGYTLNSVPPKGTICYLRATANLSTGGTAVDRTDEIHPENVWLAQ 415 Query: 400 AAAQMVGLDICGVDVVCNSVHMSLEEQGGGIVEVNAAPGLRMHLSPSYGKARDVGEAIVS 459 +++GLDI G+D+V + L E G IVEVNAAPG RMH++PS G R+V A++ Sbjct: 416 RVVKIIGLDIAGLDIVTTDISRPLRELDGVIVEVNAAPGFRMHVAPSQGIPRNVAGAVMD 475 Query: 460 TMY 462 ++ Sbjct: 476 MLF 478 >slr2002_1 [M] COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes Syn Synechocystis Length = 463 Score = 304 bits (779), Expect = 5e-82, Method: Compositional matrix adjust. Identities = 189/463 (40%), Positives = 260/463 (56%), Gaps = 18/463 (3%) Query: 1 MDVSRIRALRGPNLWS-RHTAIEAIVSCPED--ERVIDNMPGFELRLRARFPQI--GFLE 55 M + + LRGPN WS R + + ED ER +++PGF L P + F Sbjct: 1 MKILKTLTLRGPNYWSIRRKKLIVMRLDLEDLAERPSNSIPGFYEGLIRVLPSLVEHFCS 60 Query: 56 PD--GG-----KQVVSLAHALAAAALGLQSQAGCPVTFSRTVSTVETGIYQVVVEYSEEE 108 P GG ++ + H + AL LQ G F RT T GIY VV EY +E+ Sbjct: 61 PGHRGGFLARVREGTYMGHIVEHVALELQELVGMTAGFGRTRETSTPGIYNVVYEYVDEQ 120 Query: 109 VGRLAFDLALELVRAAQADAPFDLTAA---LTRIRELDEDVRLGPSTGSIVNAAIKRGIP 165 GR A A+ L R+ + LT L +R+L + LGPST +IV A R IP Sbjct: 121 AGRYAGRAAVRLCRSLVDTGDYSLTELEKDLEDLRDLGANSALGPSTETIVTEADARKIP 180 Query: 166 FRRLTQGSMVQFGWGSRQKRIQAAETSNTSAIAESIAQDKDLTKMLLHAAGVPVPNGRVV 225 + L+ +MVQ G+G Q+RIQA +S++ + +A DK+ TK +L AG+PVP G + Sbjct: 181 WMLLSARAMVQLGYGVHQQRIQATLSSHSGILGVELACDKEGTKTILQDAGIPVPRGTTI 240 Query: 226 ETVEDALKAAEEIGSA-VVIKPLDGNQGKGVAVNISTPEQITRAFNNAALISDE--VIVE 282 + +D +A ++G VVIKPLDGN G+G+ +N+ E+ A++ AA S +IVE Sbjct: 241 QYFDDLEEAINDVGGYPVVIKPLDGNHGRGITINVRHWEEAIAAYDLAAEESKSRSIIVE 300 Query: 283 RYLPGHDFRLLVIGKTLVAAARRDPPQVIGDGVHTIRQLIDQVNADPLRGDGHATSLTKI 342 RY G D R+LV+ LVA A R P V GDG TI +LID+ N DP RGDGHA LTKI Sbjct: 301 RYYEGSDHRVLVVNGKLVAVAERIPAHVTGDGTSTITELIDKTNQDPNRGDGHANILTKI 360 Query: 343 RLDDIALSVLSGQNLDPEAIPAQGVRVVLRNNANLSTGGTATDVTDDVHPDVAARAIAAA 402 ++ A+ V+ Q + +++ + V LR ANLSTGG A D TDD+HP+ A Sbjct: 361 VVNKTAIDVMERQGYNLDSVLPKDEVVYLRATANLSTGGIAIDRTDDIHPENIWLMERVA 420 Query: 403 QMVGLDICGVDVVCNSVHMSLEEQGGGIVEVNAAPGLRMHLSP 445 +++GLDI G+DVV + + L E G IVEVNAAPG RMH++P Sbjct: 421 KVIGLDIAGIDVVTSDISKPLRETNGVIVEVNAAPGFRMHVAP 463 >slr2002_2 [M] COG0769 UDP-N-acetylmuramyl tripeptide synthase Syn Synechocystis Length = 410 Score = 242 bits (618), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 157/409 (38%), Positives = 234/409 (57%), Gaps = 5/409 (1%) Query: 446 SYGKARDVGEAIVSTMYEDGDDGRIPVVAVAGTNGKTTTVRLITHLLAKTGLRVGMTNTD 505 S G R+V ++ ++ G RIP++AV GTNGKTTT RL+ H+ +TG VG T+TD Sbjct: 1 SQGLPRNVAAPVLDMLFPSGTPSRIPILAVTGTNGKTTTTRLLAHIYRQTGKTVGYTSTD 60 Query: 506 GVYIDGQRTDTGDCSGPRSARNVLFHPDVDAAVLETARGGVLREGLGFDRCAVAVVTNIG 565 +YI+ + GD +GP+SA +L P V+ AVLETARGG+LR GL FD C V VV N+ Sbjct: 61 AIYINEYCVEKGDNTGPQSAAVILRDPTVEVAVLETARGGILRAGLAFDTCDVGVVLNVA 120 Query: 566 MGDHLGLSYISTVEDLAVVKRVIVENVAPTGTAVLNAADPMVAKMAASCPGAVTFFALDP 625 DHLGL I T+E +A VK VI E V P+G AVLNA DP+VA MA V +F+++P Sbjct: 121 -ADHLGLGDIDTIEQMAKVKSVIAEVVDPSGYAVLNADDPLVAAMADKVKAKVAYFSMNP 179 Query: 626 THPIMATH-RAQGHRIVYRDGDAIVAAQGSFEKRLKLSG-IPLTRAGAIGFQVENVMASV 683 +P++ H R G VY G + +GS+ R++ + IP+T G F + N +A+ Sbjct: 180 DNPVIQNHIRRNGIAAVYESG-YVSILEGSWTLRVEEATLIPMTMGGMAPFMIANALAAC 238 Query: 684 GAAWALNLDWEQITGALASFISDSGTAPGRFNLFDYKGATLIADYGHNPDAIQALIKAVD 743 AA+ LD E I + +F + + PGR NLF+ + DY HNP +A+ V Sbjct: 239 LAAFVNGLDVEVIRQGVRTFTTSAEQTPGRMNLFNLGRYHALVDYAHNPAGYRAVGDFVK 298 Query: 744 SMPAKRRSVVISGAGDRRDVDITRQTELLGDAFDEVVLYQDQCQRGREDGEVIALLRQGL 803 + +R VV G GDRRD D+ ++ FD +++ +D +RGR GE L+ +G+ Sbjct: 299 NWHGQRFGVV-GGPGDRRDSDLIELGQIAAQVFDRIIVKEDDDKRGRSGGETADLIVKGI 357 Query: 804 SKASRTSDVKEINGEFLAIDTALGSLQPGDLCLILIDQVEEALAHIDTR 852 + + + + I E +A++ AL ++ L ++ + V +A+ I R Sbjct: 358 LQENPGAAYEVILDETVALNKALDQVEEKGLVVVFPESVSKAIELIKAR 406 >all3879_2 [M] COG0769 UDP-N-acetylmuramyl tripeptide synthase Nos Nostoc sp. PCC 7120 Length = 422 Score = 220 bits (560), Expect = 1e-56, Method: Compositional matrix adjust. Identities = 146/391 (37%), Positives = 213/391 (54%), Gaps = 4/391 (1%) Query: 468 GRIPVVAVAGTNGKTTTVRLITHLLAKTGLRVGMTNTDGVYIDGQRTDTGDCSGPRSARN 527 GRIP+++V GTNGKTTT RL+ H+ +TG VG T TDG YI ++GD +GP+SA Sbjct: 5 GRIPILSVTGTNGKTTTTRLLAHIYKQTGKVVGYTTTDGTYIGDYLVESGDNTGPQSAHV 64 Query: 528 VLFHPDVDAAVLETARGGVLREGLGFDRCAVAVVTNIGMGDHLGLSYISTVEDLAVVKRV 587 +L P V+ AVLETARGG+LR GLGF+ V VV N+ DHLG+ I T++ LA +K V Sbjct: 65 ILQDPTVEVAVLETARGGILRSGLGFESANVGVVLNVA-ADHLGIGDIDTIDQLANLKSV 123 Query: 588 IVENVAPTGTAVLNAADPMVAKMAASCPGAVTFFALDPTHPIMATHRAQGHRIVYRDGDA 647 + E+V P G AVLNA D VA MA + +F ++ ++ H +G + Sbjct: 124 VAESVYPDGYAVLNADDRRVAAMAEKTKANIAYFTMNSESELVRKHIQKGGVAAVYENGY 183 Query: 648 IVAAQGSFEKRL-KLSGIPLTRAGAIGFQVENVMASVGAAWALNLDWEQITGALASFISD 706 + +G + R+ + IPLT G F + N +A+ AA+ N+ EQI L +F + Sbjct: 184 LSIVKGDWTHRIERAEQIPLTMGGRAPFMIANALAASLAAFVQNVSIEQIRAGLRTFRAS 243 Query: 707 SGTAPGRFNLFDYKGATLIADYGHNPDAIQALIKAVDSMPAKRRSVVISGAGDRRDVDIT 766 PGR NLF+ + DY HNP + +A+ V + + +R V+ G GDRRD D Sbjct: 244 VSQTPGRMNLFNLGNYHALVDYAHNPASYEAVGAFVRNWTSGQRIGVVGGPGDRRDEDFV 303 Query: 767 RQTELLGDAFDEVVLYQDQCQRGREDGEVIALLRQGLSKASRTSDVKEINGEFLAIDTAL 826 +L + FD +++ +D RGR G L+ +G+++ + + I E AI+ L Sbjct: 304 TLGKLAAEIFDYIIVKEDDDTRGRPRGSASELITKGITQVKPDARYESILDETQAINKGL 363 Query: 827 GSLQPGDLCLILIDQVEEALAHIDTR--VKE 855 L +IL + V A+ I R VKE Sbjct: 364 DMAPANGLVVILPESVSRAIKLIKLRGLVKE 394 >alr0573 [M] COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes Nos Nostoc sp. PCC 7120 Length = 636 Score = 209 bits (532), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 130/421 (30%), Positives = 216/421 (51%), Gaps = 8/421 (1%) Query: 149 GPSTGSIVNAAIKRGIPFRRLTQGSMVQFGWGSRQKRIQAAETSNTSAIAESIAQDKDLT 208 GP+ +++ A ++GIP L ++Q+GWG + R A + S I KD Sbjct: 161 GPTVYALLRTAYEKGIPTFYLWDEGLMQYGWGKKHIRGVATTFNCDSHIDSDFTTRKDDC 220 Query: 209 KMLLHAAGVPVPNGRVVETVEDALKAAEEIGSAVVIKPLDGNQGKGVAVNISTPEQITRA 268 K LH G PVP G +V + ++A + A++IG V +KP+ G++G GV ++ +++ A Sbjct: 221 KAFLHTLGFPVPQGEIVYSPKEARQVAKDIGYPVAVKPVVGHKGIGVTADVKDVDELEVA 280 Query: 269 FNNA--ALISDE---VIVERYLPGHDFRLLVIGKTLVAAARRDPPQVIGDGVHTIRQLID 323 ++ A A+ +E +IVE+ + G DFRLL + VAA R P V+GDG TI +LI Sbjct: 281 YDRALEAIPENEPARIIVEKSIKGKDFRLLCVNGRFVAATERHPASVVGDGDSTIWELIQ 340 Query: 324 QVNADPLRGDGHATSLTKIRLDDIALSVLSGQNLDPEAIPAQGVRVVLRNNANLSTGGTA 383 + N +R D + ++KI +DD L Q L + + +G V LR ANLS GG + Sbjct: 341 KENRKAVRLDTPTSPMSKIIVDDAMEHYLEEQRLSLKTVLDKGETVHLRKVANLSAGGMS 400 Query: 384 TDVTDDVHPDVAARAIAAAQMVGLDICGVDVVCNSVHMSLEEQGGGIVEVNAAPGLRMHL 443 + T +H D A AQ L G+DV+ + S + I+E+NAAPG+ MHL Sbjct: 401 INATHAIHDDNIILAQDIAQYFRLTCLGIDVIAEDLSESWKVGNFAIIEINAAPGVMMHL 460 Query: 444 SPSYGKARDVGEAIVSTMYEDGDDGRIPVVAVAGTNGKTTTVRLITHLLAKTGLRVGMTN 503 +P+ G++ DV I+ T +E G D RIP++ + + + LL +G Sbjct: 461 NPAVGESVDVPSHILETFFESGLDARIPIMTFNKISVEELQTTIDHILLQHPEWTIGAVC 520 Query: 504 TDGVYID-GQRTDTGDCSGPRSARNVLFHPDVDAAVLETARGGVLREGLGFDRCAVAVVT 562 D V+++ Q+ D + + +++L +P +D + E + +G+ + + V+ Sbjct: 521 RDAVFVNRSQKVLRDDYNS--NIQSLLRNPKLDLLIAEYPEDTLEEDGMFYQGSNLVVLD 578 Query: 563 N 563 N Sbjct: 579 N 579 >CAC1540 [M] COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes Cac Clostridium acetobutylicum Length = 328 Score = 187 bits (476), Expect = 8e-47, Method: Compositional matrix adjust. Identities = 117/336 (34%), Positives = 177/336 (52%), Gaps = 26/336 (7%) Query: 142 LDED-VRLGPSTGSIVNAAIKRGIP---------FRRLTQGSMVQFGWGSRQKRIQAAET 191 ++ED +L ST ++N A+ R I F RL +G V++ QA +T Sbjct: 1 MNEDYTKLELSTQILINEALDRKIQVDILDMEDNFIRLKKGDKVEYVK-------QATKT 53 Query: 192 SNTSAIAESIAQDKDLTKMLLHAAGVPVPNGRVVETVEDALKAAEEI----GSAVVIKPL 247 S + IA I ++K++TK++L G+ VP G T+++A +A E+ G V+KP Sbjct: 54 SLDNYIAPLIMENKEVTKIVLKENGINVPEGV---TLKEASEAKEKFSLFYGKDTVVKPK 110 Query: 248 DGNQGKGVAV--NISTPEQITRAFNNAALISDEVIVERYLPGHDFRLLVIGKTLVAAARR 305 N GKGV + + + E A N A + V+VE ++ G ++R LVIG +A R Sbjct: 111 STNFGKGVIILKQLRSIEDFENAVNQAFEYDNSVMVEEFIAGKEYRFLVIGDETIAVLHR 170 Query: 306 DPPQVIGDGVHTIRQLIDQVNADPLRGDGHATSLTKIRLDDIALSVLSGQNLDPEAIPAQ 365 P VIGDGVH+I++L+D+ N DP RG G+ L KI L I LS N D + +P + Sbjct: 171 VPANVIGDGVHSIKELVDEKNKDPRRGQGYVKPLEKIVLGTIEKEYLSFSNRDFDYVPDK 230 Query: 366 GVRVVLRNNANLSTGGTATDVTDDVHPDVAARAIAAAQMVGLDICGVDVVCNSVHMSLEE 425 V LR N+N+STGG + D TD++ A+ AA VG ICG D++ N ++ Sbjct: 231 NEIVYLRENSNVSTGGDSIDFTDEILEGYKKIAVRAANAVGAKICGADIIINDINEEPNA 290 Query: 426 QGGGIVEVNAAPGLRMHLSPSYGKARDVGEAIVSTM 461 + I+E+N P + MH P G+ R V I+ + Sbjct: 291 KNHSIIELNFNPAIHMHDFPYRGENRHVERKILDLL 326 >lin2913_2 [M] COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes Lin Listeria innocua Length = 318 Score = 177 bits (449), Expect = 9e-44, Method: Compositional matrix adjust. Identities = 108/318 (33%), Positives = 170/318 (53%), Gaps = 7/318 (2%) Query: 151 STGSIVNAAIKRGIPFRRLTQG-SMVQFGWGSRQKRI-QAAETSNTSAIAESIAQDKDLT 208 ST I AI RGI L + + ++F G + + QA++TS + ++ + ++K +T Sbjct: 3 STQIIWKDAIARGIKVDVLDRAENFLRFQKGDHVEYVKQASKTSKDNYVSVLMMENKVVT 62 Query: 209 KMLLHAAGVPVPNGRVVETVEDALKAAEEI-GSAVVIKPLDGNQGKGVAV--NISTPEQI 265 K++L G+ VP G AL+A +V+KP N G G+++ N T E Sbjct: 63 KLVLAEHGIRVPFGDSFSDQALALEAFSLFEDKQIVVKPKSTNYGWGISIFKNKFTLEDY 122 Query: 266 TRAFNNAALISDEVIVERYLPGHDFRLLVIGKTLVAAARRDPPQVIGDGVHTIRQLIDQV 325 A N A VI+E ++PG +FR LVI + A +R P V GDG+HT+RQL+++ Sbjct: 123 QEALNIAFSYDSSVIIEEFIPGDEFRFLVINDKVEAVLKRVPANVTGDGIHTVRQLVEEK 182 Query: 326 NADPLRGDGHATSLTKIRLDDIALSVLSGQNLDPEAIPAQGVRVVLRNNANLSTGGTATD 385 N DPLRG H L KIR +LS QNL ++IP + LR N+N+STGG + D Sbjct: 183 NTDPLRGTDHLKPLEKIRTGPEETLMLSMQNLSWDSIPKAEEIIYLRENSNVSTGGDSID 242 Query: 386 VTDDVHPDVAARAIAAAQMVGLDICGVDVVCNSVHMSLEEQGGGIVEVNAAPGLRMHLSP 445 T+++ AI A Q++ ICGVD++ +++ I+E+N P + MH P Sbjct: 243 YTEEMDDYFKEIAIRATQVLDAKICGVDIIVP--RETIDRDKHAIIELNFNPAMHMHCFP 300 Query: 446 SYGKARDVGEAIVSTMYE 463 G+ + +G+ I+ ++E Sbjct: 301 YQGEKKKIGDKILDFLFE 318 >BH3654_1 [M] COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes Bha Bacillus halodurans Length = 380 Score = 169 bits (427), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 107/305 (35%), Positives = 158/305 (51%), Gaps = 15/305 (4%) Query: 175 VQFGWGSRQKRIQAAETSNTSAIAE--SIAQDKDLTKMLLHAAGVPVPNGRVVETVE--- 229 V + + +K Q A + E SI +KD+TK L A VPVP G+ + Sbjct: 53 VVYSLANEEKEHQFAVSRGDKVTKEAISICINKDITKEYLEKANVPVPEGKGFNEAQADS 112 Query: 230 DALKAAEEIGSAVVIKPLDGNQGKGVAVNISTPEQITRA--FNNAALISDEVIVERYLPG 287 D ++ A+E+G VVIKP DG GKGV VNI E + A + L V+VERY G Sbjct: 113 DIIQYAKELGFPVVIKPTDGLSGKGVVVNIQNEEMLREAISYVREQLAYSNVVVERYFEG 172 Query: 288 HDFRLLVIGKTLVAAARRDPPQVIGDGVHTIRQLIDQVNADPLRGDGHATSLTKIRLDDI 347 DFR+ ++G ++ A R P V+GDG TI+QLI N R I+LD Sbjct: 173 EDFRIYIMGDQVIGAVTRVPANVVGDGKRTIKQLIKLKNK--ARNKNPNLQRRPIKLDHE 230 Query: 348 ALSVLSGQNLDPEAIPAQGVRVVLRNNANLSTGGTATDVTDDVHPDVAARAIAAAQMV-G 406 L+ N ++IP++G RV+L +N+STGG DVTD + P++ A+ AA+ + G Sbjct: 231 LEKTLNLINYTIDSIPSKGERVILNTKSNISTGGEPVDVTDQLTPEIKKIAVQAAKAIPG 290 Query: 407 LDICGVDVVCNSVHMSLEEQGGGIVEVNAAPGLRMHLSPSYGKARDVGEAIVSTMYEDGD 466 L C VD++ + E G ++E+N+ P + HL P GKA ++ AI+ + + Sbjct: 291 LIHCAVDMLVDK-----ENNNGVVLEINSKPQIGAHLFPMEGKAVNIPRAIIDYYFPETK 345 Query: 467 DGRIP 471 + IP Sbjct: 346 EDPIP 350 >PM1048_2 [M] COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes Pmu Pasteurella multocida Length = 276 Score = 152 bits (384), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 91/274 (33%), Positives = 143/274 (52%), Gaps = 6/274 (2%) Query: 197 IAESIAQDKDLTKMLLHAAGVPVPNGRVVETVEDALKAAEEI-GSAVVIKPLDGNQGKGV 255 I+ I ++K +TK +L AG VP ++E A+ + AVVIKP N G G+ Sbjct: 1 ISPLIMENKVVTKKVLQKAGFNVPQSVEFTSLEKAVASYALFENRAVVIKPKSTNYGLGI 60 Query: 256 AV---NISTPEQITRAFNNAALISDEVIVERYLPGHDFRLLVIGKTLVAAARRDPPQVIG 312 + + E +A A EV+VE YL G ++R V+G +A R P V+G Sbjct: 61 TIFQQGVQNREDFAKALEIAFREDKEVMVEDYLVGTEYRFFVLGDETLAVLLRVPANVVG 120 Query: 313 DGVHTIRQLIDQVNADPLRGDGHATSLTKIRLDDIALSVLSGQNLDPEAIPAQGVRVVLR 372 D VH++ +L+ N PLRGDG T L KI L +I L Q L ++IPA+ V LR Sbjct: 121 DSVHSVAELVAMKNDHPLRGDGSRTPLKKIALGEIEQLQLKEQGLTIDSIPAKDQLVQLR 180 Query: 373 NNANLSTGGTATDVTDDVHPDVAARAIAAAQMVGLDICGVDVVCNSVHMSLEEQ--GGGI 430 N+N+STGG + D+TD++H A+ + +G +CGVD++ + G+ Sbjct: 181 ANSNISTGGDSIDMTDEMHESYKQLAVGITKAMGAAVCGVDLIIPDLKQPATPNLTSWGV 240 Query: 431 VEVNAAPGLRMHLSPSYGKARDVGEAIVSTMYED 464 +E N P + MH+ P GK+R + + ++ ++ + Sbjct: 241 IEANFNPMMMMHIFPYAGKSRRLTQNVIKMLFPE 274 >BH3653_1 [M] COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes Bha Bacillus halodurans Length = 386 Score = 150 bits (380), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 99/271 (36%), Positives = 146/271 (53%), Gaps = 10/271 (3%) Query: 198 AESIAQDKDLTKMLLHAAGVPVPNGRVVE---TVEDALKAAEEIGSAVVIKPLDGNQGKG 254 A I DKD TK+ L AGVPVP GR T ++ ++ A + +VIKP++G+ G G Sbjct: 89 AVEIGSDKDETKIWLSKAGVPVPEGRKFSEEATDDEIIQYASTLEYPLVIKPVNGSLGNG 148 Query: 255 VAVNISTPEQITRAFN--NAALISDEVIVERYLPGHDFRLLVIGKTLVAAARRDPPQVIG 312 V NI + + +A N + L EVIVERY+PG ++RL VI ++ A R P +IG Sbjct: 149 VITNIKNEQVLRKALNYVRSDLEYLEVIVERYVPGEEYRLYVIEDKVIGAYNRLPANIIG 208 Query: 313 DGVHTIRQLIDQVNADPLRGDGHATSLTKIRLDDIALSVLSGQNLDPEAIPAQGVRVVLR 372 DG HTI +LI N + + L +I L+ + +G NL +IP G R++L+ Sbjct: 209 DGQHTIEELIHLKNLQRRKNARLFSCLIEIDLETLDFIEDAGYNLS--SIPKDGERILLK 266 Query: 373 NNANLSTGGTATDVTDDVHPDVAARAIAAAQMV-GLDICGVDVVCNSVHMSLEEQGGGIV 431 N+S GG DVTDD+ ++ AI A + V GL GVD++ + E+G ++ Sbjct: 267 EKTNVSAGGDPIDVTDDLSEEIKQIAINAVKAVPGLYHGGVDIIVDPSKPP--EKGAVVI 324 Query: 432 EVNAAPGLRMHLSPSYGKARDVGEAIVSTMY 462 E+N + L P GKARD+ AI+ + Sbjct: 325 ELNPTAQIGGILFPMKGKARDIPAAIIDYYF 355