BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0109.p (274 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1403 [J] COG0024 Methionine aminopeptidase Rso Ralstonia sola... 427 e-120 PA3657 [J] COG0024 Methionine aminopeptidase Pae Pseudomonas aer... 357 1e-98 XF0111 [J] COG0024 Methionine aminopeptidase Xfa Xylella fastidi... 354 1e-97 NMA0337 [J] COG0024 Methionine aminopeptidase NmA Neisseria meni... 344 1e-94 NMB2093 [J] COG0024 Methionine aminopeptidase Nme Neisseria meni... 343 2e-94 map [J] COG0024 Methionine aminopeptidase Eco Escherichia coli K12 327 1e-89 Zmap [J] COG0024 Methionine aminopeptidase EcZ Escherichia coli ... 327 1e-89 ECs0170 [J] COG0024 Methionine aminopeptidase Ecs Escherichia co... 327 1e-89 STM0215 [J] COG0024 Methionine aminopeptidase Sty Salmonella typ... 322 4e-88 YPO1043 [J] COG0024 Methionine aminopeptidase Ype Yersinia pestis 318 6e-87 >RSc1403 [J] COG0024 Methionine aminopeptidase Rso Ralstonia solanacearum Length = 275 Score = 427 bits (1099), Expect = e-120, Method: Compositional matrix adjust. Identities = 197/273 (72%), Positives = 238/273 (87%), Gaps = 2/273 (0%) Query: 4 ITIKTAEDIEGMRVAGRLAAEVLDYITPFVKPGVTTGEIDRLCHEYMTNVQGSIPAPLNY 63 +T+KTAEDI MRVA RLA+EVLDYITPFVK GV+TGE+DRLCH YM +VQG++PAPLNY Sbjct: 3 VTLKTAEDIAHMRVACRLASEVLDYITPFVKAGVSTGELDRLCHAYMRDVQGTVPAPLNY 62 Query: 64 CPPGYTPYPKAICTSLNDVICHGIPGDK-VMKNGDVLNIDVTIIK-DGYHGDTSRMFFLG 121 PPGY P+P AICTS+NDVICHGIP DK ++KNGD +N+D+T+I +GY+GDTSRMF +G Sbjct: 63 APPGYPPFPGAICTSVNDVICHGIPDDKKILKNGDAINLDITVITPEGYYGDTSRMFIVG 122 Query: 122 EPSILARRLTEITYECMWLGISKIKPGAHLGDIGHVIQQHAEKAGYSVVREFCGHGIGKV 181 E SILA+RL ++TYECMW GI+ ++PGA LGDIGHVIQQHAE AGYSVVRE+CGHGIG+V Sbjct: 123 EGSILAKRLAQVTYECMWKGIAVVRPGARLGDIGHVIQQHAEAAGYSVVREYCGHGIGQV 182 Query: 182 FHEEPQVLHYGRPGTLEKLEAGMIFTVEPMINAGRREIREMGDGWTIKTKDRSLSAQWEH 241 FHE+PQ+LHYGRPGT +L+AGMIFT+EPMINAG+R+IR M D WT+KT+DRSLSAQWEH Sbjct: 183 FHEDPQILHYGRPGTGLELKAGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQWEH 242 Query: 242 TVLVTETGFEVLTVSPGMPAPPAFIQNQATAAA 274 T+LVTE G++VLTVS PAPPAF+ + A A Sbjct: 243 TILVTEAGYDVLTVSAHTPAPPAFVSDGTPATA 275 >PA3657 [J] COG0024 Methionine aminopeptidase Pae Pseudomonas aeruginosa Length = 261 Score = 357 bits (917), Expect = 1e-98, Method: Compositional matrix adjust. Identities = 168/252 (66%), Positives = 206/252 (81%), Gaps = 5/252 (1%) Query: 4 ITIKTAEDIEGMRVAGRLAAEVLDYITPFVKPGVTTGEIDRLCHEYMTNVQGSIPAPLNY 63 +TIKT +DIE MR+AGRLAAEVL+ I +KPGVTT E+DR+CH+Y+ N Q +IPAPLNY Sbjct: 3 VTIKTPDDIEKMRIAGRLAAEVLEMIGEHIKPGVTTEELDRICHDYIVNEQKAIPAPLNY 62 Query: 64 CPPGYTPYPKAICTSLNDVICHGIPGDKVMKNGDVLNIDVTIIKDGYHGDTSRMFFLGEP 123 +PK+ICTS+N V+CHGIP +K +K GD+LN+D+T+IKDGYHGDTS+MF +G+ Sbjct: 63 -----KGFPKSICTSINHVVCHGIPNEKPLKEGDILNVDITVIKDGYHGDTSKMFLVGKT 117 Query: 124 SILARRLTEITYECMWLGISKIKPGAHLGDIGHVIQQHAEKAGYSVVREFCGHGIGKVFH 183 A RL +IT ECM+ GIS ++PGAHLGDIG +IQ+HAEK G+SVVRE+CGHGIGKVFH Sbjct: 118 PEWADRLCQITQECMYKGISVVRPGAHLGDIGEIIQKHAEKNGFSVVREYCGHGIGKVFH 177 Query: 184 EEPQVLHYGRPGTLEKLEAGMIFTVEPMINAGRREIREMGDGWTIKTKDRSLSAQWEHTV 243 EEPQVLHYGR GT +L+ GMIFT+EPMIN GR E R +GDGWT TKDR LSAQWEHTV Sbjct: 178 EEPQVLHYGRAGTGIELKEGMIFTIEPMINQGRPETRLLGDGWTAITKDRKLSAQWEHTV 237 Query: 244 LVTETGFEVLTV 255 LVT G+E+LT+ Sbjct: 238 LVTADGYEILTL 249 >XF0111 [J] COG0024 Methionine aminopeptidase Xfa Xylella fastidiosa 9a5c Length = 259 Score = 354 bits (908), Expect = 1e-97, Method: Compositional matrix adjust. Identities = 165/258 (63%), Positives = 205/258 (79%), Gaps = 6/258 (2%) Query: 1 MGNITIKTAEDIEGMRVAGRLAAEVLDYITPFVKPGVTTGEIDRLCHEYMTNVQGSIPAP 60 M + +KT E+IE MR+AGRLAA VLD + P+VKPGVTT E+D++CH+Y+ VQG+IPA Sbjct: 1 MVAVNLKTKEEIEQMRIAGRLAATVLDVVAPYVKPGVTTAELDQICHDYIVTVQGAIPAN 60 Query: 61 LNYCPPGYTPYPKAICTSLNDVICHGIPGD-KVMKNGDVLNIDVTIIKDGYHGDTSRMFF 119 L GY +PK ICTS+N+VICHGIP D KV+K+GD++NIDVT+IKDG+HGDTSRM++ Sbjct: 61 L-----GYRGFPKTICTSVNNVICHGIPSDAKVLKDGDIINIDVTVIKDGWHGDTSRMYY 115 Query: 120 LGEPSILARRLTEITYECMWLGISKIKPGAHLGDIGHVIQQHAEKAGYSVVREFCGHGIG 179 +G PS++ARRL E TYE MW GI +KPGA LGDIGH IQ +AE +SVVRE+CGHGIG Sbjct: 116 VGNPSVMARRLVETTYEAMWRGIRAVKPGATLGDIGHAIQIYAENERFSVVREYCGHGIG 175 Query: 180 KVFHEEPQVLHYGRPGTLEKLEAGMIFTVEPMINAGRREIREMGDGWTIKTKDRSLSAQW 239 KV+H+ PQVLHYGRPG LE+GM FT+EPMIN G R + + DGWT+ TKDR LSAQW Sbjct: 176 KVYHDNPQVLHYGRPGEGLVLESGMTFTIEPMINEGTRHHKVLPDGWTVVTKDRKLSAQW 235 Query: 240 EHTVLVTETGFEVLTVSP 257 EH + VTE G +VLT+SP Sbjct: 236 EHMIAVTEDGVDVLTLSP 253 >NMA0337 [J] COG0024 Methionine aminopeptidase NmA Neisseria meningitidis Z2491 Length = 259 Score = 344 bits (883), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 167/262 (63%), Positives = 201/262 (76%), Gaps = 3/262 (1%) Query: 1 MGNITIKTAEDIEGMRVAGRLAAEVLDYITPFVKPGVTTGEIDRLCHEYMTNVQGSIPAP 60 M I IKT E+IE MR G+L AE LDYI FVKPGVTT EID+L ++Y NVQG PAP Sbjct: 1 MNGIIIKTPEEIEKMRELGKLVAEALDYIGQFVKPGVTTDEIDKLVYDYHVNVQGGYPAP 60 Query: 61 LNYCPPGYTPYPKAICTSLNDVICHGIPGDKVMKNGDVLNIDVTIIKDGYHGDTSRMFFL 120 L+Y P PYPK+ CTS+N VICHGIP DK +K GD++NID+TI KDG+HGD+SRMF + Sbjct: 61 LHYGNP---PYPKSCCTSVNHVICHGIPDDKPLKEGDIINIDLTIKKDGFHGDSSRMFTV 117 Query: 121 GEPSILARRLTEITYECMWLGISKIKPGAHLGDIGHVIQQHAEKAGYSVVREFCGHGIGK 180 G+ S +A+RL ++T+ M GI +KPGA LGD+G+ QQ AE AGYSVV+EFCGHGIG+ Sbjct: 118 GKVSPIAQRLIDVTHASMMAGIEAVKPGATLGDVGYACQQVAENAGYSVVQEFCGHGIGR 177 Query: 181 VFHEEPQVLHYGRPGTLEKLEAGMIFTVEPMINAGRREIREMGDGWTIKTKDRSLSAQWE 240 FHE PQVLHYG+ G L+ GMIFTVEPMIN G+R +R + DGWT+ TKDRSLSAQWE Sbjct: 178 GFHEAPQVLHYGKKGQGSVLKPGMIFTVEPMINQGKRHLRILNDGWTVVTKDRSLSAQWE 237 Query: 241 HTVLVTETGFEVLTVSPGMPAP 262 H VLVTETG+E+LTVSP P Sbjct: 238 HEVLVTETGYEILTVSPASGKP 259 >NMB2093 [J] COG0024 Methionine aminopeptidase Nme Neisseria meningitidis MC58 Length = 259 Score = 343 bits (880), Expect = 2e-94, Method: Compositional matrix adjust. Identities = 167/262 (63%), Positives = 201/262 (76%), Gaps = 3/262 (1%) Query: 1 MGNITIKTAEDIEGMRVAGRLAAEVLDYITPFVKPGVTTGEIDRLCHEYMTNVQGSIPAP 60 M I IKT E+IE MR G+L AE LDYI FVKPGVTT EID+L ++Y NVQG PAP Sbjct: 1 MNGIIIKTPEEIEKMRELGKLVAEALDYIGQFVKPGVTTDEIDKLVYDYHVNVQGGYPAP 60 Query: 61 LNYCPPGYTPYPKAICTSLNDVICHGIPGDKVMKNGDVLNIDVTIIKDGYHGDTSRMFFL 120 L+Y P PYPK+ CTS+N VICHGIP DK +K GD++NID+TI KDG+HGD+SRMF + Sbjct: 61 LHYGNP---PYPKSCCTSVNHVICHGIPDDKPLKEGDIINIDLTIKKDGFHGDSSRMFTV 117 Query: 121 GEPSILARRLTEITYECMWLGISKIKPGAHLGDIGHVIQQHAEKAGYSVVREFCGHGIGK 180 G+ S +A+RL ++T+ M GI +KPGA LGD+G+ QQ AE AGYSVV+EFCGHGIG+ Sbjct: 118 GKVSPIAQRLIDVTHASMMAGIEAVKPGATLGDVGYACQQVAENAGYSVVQEFCGHGIGR 177 Query: 181 VFHEEPQVLHYGRPGTLEKLEAGMIFTVEPMINAGRREIREMGDGWTIKTKDRSLSAQWE 240 FHE PQVLHYG+ G L+ GMIFTVEPMIN G+R +R + DGWT+ TKDRSLSAQWE Sbjct: 178 GFHEAPQVLHYGKKGQGPVLKPGMIFTVEPMINQGKRHLRILNDGWTVVTKDRSLSAQWE 237 Query: 241 HTVLVTETGFEVLTVSPGMPAP 262 H VLVTETG+E+LTVSP P Sbjct: 238 HEVLVTETGYEILTVSPASGKP 259 >map [J] COG0024 Methionine aminopeptidase Eco Escherichia coli K12 Length = 264 Score = 327 bits (839), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 153/267 (57%), Positives = 205/267 (76%), Gaps = 6/267 (2%) Query: 4 ITIKTAEDIEGMRVAGRLAAEVLDYITPFVKPGVTTGEIDRLCHEYMTNVQGSIPAPLNY 63 I+IKT EDIE MRVAGRLAAEVL+ I P+VKPGV+TGE+DR+C++Y+ N Q ++ A L Sbjct: 3 ISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACL-- 60 Query: 64 CPPGYTPYPKAICTSLNDVICHGIPGD-KVMKNGDVLNIDVTIIKDGYHGDTSRMFFLGE 122 GY YPK++C S+N+V+CHGIP D K++K+GD++NIDVT+IKDG+HGDTS+MF +G+ Sbjct: 61 ---GYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGK 117 Query: 123 PSILARRLTEITYECMWLGISKIKPGAHLGDIGHVIQQHAEKAGYSVVREFCGHGIGKVF 182 P+I+ RL IT E ++L + +KPG +L +IG IQ+ E G+SVVRE+CGHGIG+ F Sbjct: 118 PTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGF 177 Query: 183 HEEPQVLHYGRPGTLEKLEAGMIFTVEPMINAGRREIREMGDGWTIKTKDRSLSAQWEHT 242 HEEPQVLHY T L+ GM FT+EPM+NAG++EIR M DGWT+KTKDRSLSAQ+EHT Sbjct: 178 HEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHT 237 Query: 243 VLVTETGFEVLTVSPGMPAPPAFIQNQ 269 ++VT+ G E+LT+ P ++ Sbjct: 238 IVVTDNGCEILTLRKDDTIPAIISHDE 264 >Zmap [J] COG0024 Methionine aminopeptidase EcZ Escherichia coli O157:H7 EDL933 Length = 264 Score = 327 bits (839), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 153/267 (57%), Positives = 205/267 (76%), Gaps = 6/267 (2%) Query: 4 ITIKTAEDIEGMRVAGRLAAEVLDYITPFVKPGVTTGEIDRLCHEYMTNVQGSIPAPLNY 63 I+IKT EDIE MRVAGRLAAEVL+ I P+VKPGV+TGE+DR+C++Y+ N Q ++ A L Sbjct: 3 ISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACL-- 60 Query: 64 CPPGYTPYPKAICTSLNDVICHGIPGD-KVMKNGDVLNIDVTIIKDGYHGDTSRMFFLGE 122 GY YPK++C S+N+V+CHGIP D K++K+GD++NIDVT+IKDG+HGDTS+MF +G+ Sbjct: 61 ---GYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGK 117 Query: 123 PSILARRLTEITYECMWLGISKIKPGAHLGDIGHVIQQHAEKAGYSVVREFCGHGIGKVF 182 P+I+ RL IT E ++L + +KPG +L +IG IQ+ E G+SVVRE+CGHGIG+ F Sbjct: 118 PTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGF 177 Query: 183 HEEPQVLHYGRPGTLEKLEAGMIFTVEPMINAGRREIREMGDGWTIKTKDRSLSAQWEHT 242 HEEPQVLHY T L+ GM FT+EPM+NAG++EIR M DGWT+KTKDRSLSAQ+EHT Sbjct: 178 HEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHT 237 Query: 243 VLVTETGFEVLTVSPGMPAPPAFIQNQ 269 ++VT+ G E+LT+ P ++ Sbjct: 238 IVVTDNGCEILTLRKDDTIPAIISHDE 264 >ECs0170 [J] COG0024 Methionine aminopeptidase Ecs Escherichia coli O157:H7 Length = 264 Score = 327 bits (839), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 153/267 (57%), Positives = 205/267 (76%), Gaps = 6/267 (2%) Query: 4 ITIKTAEDIEGMRVAGRLAAEVLDYITPFVKPGVTTGEIDRLCHEYMTNVQGSIPAPLNY 63 I+IKT EDIE MRVAGRLAAEVL+ I P+VKPGV+TGE+DR+C++Y+ N Q ++ A L Sbjct: 3 ISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACL-- 60 Query: 64 CPPGYTPYPKAICTSLNDVICHGIPGD-KVMKNGDVLNIDVTIIKDGYHGDTSRMFFLGE 122 GY YPK++C S+N+V+CHGIP D K++K+GD++NIDVT+IKDG+HGDTS+MF +G+ Sbjct: 61 ---GYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGK 117 Query: 123 PSILARRLTEITYECMWLGISKIKPGAHLGDIGHVIQQHAEKAGYSVVREFCGHGIGKVF 182 P+I+ RL IT E ++L + +KPG +L +IG IQ+ E G+SVVRE+CGHGIG+ F Sbjct: 118 PTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGF 177 Query: 183 HEEPQVLHYGRPGTLEKLEAGMIFTVEPMINAGRREIREMGDGWTIKTKDRSLSAQWEHT 242 HEEPQVLHY T L+ GM FT+EPM+NAG++EIR M DGWT+KTKDRSLSAQ+EHT Sbjct: 178 HEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHT 237 Query: 243 VLVTETGFEVLTVSPGMPAPPAFIQNQ 269 ++VT+ G E+LT+ P ++ Sbjct: 238 IVVTDNGCEILTLRKDDTIPAIISHDE 264 >STM0215 [J] COG0024 Methionine aminopeptidase Sty Salmonella typhimurium LT2 Length = 264 Score = 322 bits (826), Expect = 4e-88, Method: Compositional matrix adjust. Identities = 155/267 (58%), Positives = 201/267 (75%), Gaps = 6/267 (2%) Query: 4 ITIKTAEDIEGMRVAGRLAAEVLDYITPFVKPGVTTGEIDRLCHEYMTNVQGSIPAPLNY 63 I+IKT+EDIE MRVAGRLAAEVL+ I P++KPGVTTGE+DR+C++Y+ N Q +I A L Sbjct: 3 ISIKTSEDIEKMRVAGRLAAEVLEMIEPYIKPGVTTGELDRICNDYIVNEQHAISACL-- 60 Query: 64 CPPGYTPYPKAICTSLNDVICHGIPGD-KVMKNGDVLNIDVTIIKDGYHGDTSRMFFLGE 122 GY YPK++C S+N+V+CHGIP D K +K+GD++NIDVT+IKD +HGDTS+MF +G+ Sbjct: 61 ---GYHGYPKSVCISINEVVCHGIPDDAKHLKDGDIVNIDVTVIKDEFHGDTSKMFIVGK 117 Query: 123 PSILARRLTEITYECMWLGISKIKPGAHLGDIGHVIQQHAEKAGYSVVREFCGHGIGKVF 182 P+IL RL +T E ++LGI +KPG L IG IQ++AE G+SVVRE+CGHGIG+ F Sbjct: 118 PTILGERLCRVTQESLYLGIKMVKPGIRLRTIGAAIQKYAEGEGFSVVREYCGHGIGRGF 177 Query: 183 HEEPQVLHYGRPGTLEKLEAGMIFTVEPMINAGRREIREMGDGWTIKTKDRSLSAQWEHT 242 HEEPQVLHY L+ GM FT+EPM+NAG IR M DGWT+KTKDRSLSAQ+EHT Sbjct: 178 HEEPQVLHYDADDGGVVLQPGMTFTIEPMLNAGDYRIRTMKDGWTVKTKDRSLSAQYEHT 237 Query: 243 VLVTETGFEVLTVSPGMPAPPAFIQNQ 269 ++VTE G E+LT+ P ++ Sbjct: 238 IVVTENGCEILTLRKDDTIPAIITHDE 264 >YPO1043 [J] COG0024 Methionine aminopeptidase Ype Yersinia pestis Length = 263 Score = 318 bits (816), Expect = 6e-87, Method: Compositional matrix adjust. Identities = 152/260 (58%), Positives = 197/260 (75%), Gaps = 6/260 (2%) Query: 4 ITIKTAEDIEGMRVAGRLAAEVLDYITPFVKPGVTTGEIDRLCHEYMTNVQGSIPAPLNY 63 I+IKT EDI+ MRVAGRLAAEVL+ I P+VKPGVTTGE+DR+CH+++TN Q +I A L Sbjct: 3 ISIKTPEDIQKMRVAGRLAAEVLEIIEPYVKPGVTTGELDRICHDHITNHQQAISACL-- 60 Query: 64 CPPGYTPYPKAICTSLNDVICHGIPGD-KVMKNGDVLNIDVTIIKDGYHGDTSRMFFLGE 122 GY +PK++C S+N+VICHGIP D KV+K GD++NIDVT+IKDG+HGDTS+MF +G+ Sbjct: 61 ---GYHGFPKSVCISVNEVICHGIPSDEKVLKEGDIVNIDVTVIKDGFHGDTSKMFIVGK 117 Query: 123 PSILARRLTEITYECMWLGISKIKPGAHLGDIGHVIQQHAEKAGYSVVREFCGHGIGKVF 182 P+IL RL +T E ++L I +KPG L +G IQ+ E +SVVRE+CGHGIG+ F Sbjct: 118 PTILGERLCRVTQESLYLAIKMVKPGIRLRTLGKAIQKFVEAENFSVVREYCGHGIGEGF 177 Query: 183 HEEPQVLHYGRPGTLEKLEAGMIFTVEPMINAGRREIREMGDGWTIKTKDRSLSAQWEHT 242 HEEPQVLHY L+AGM FT+EPM+NAG IR M DGWT+KTKDR+LSAQ+EHT Sbjct: 178 HEEPQVLHYDADDGGVVLQAGMAFTIEPMVNAGDYRIRTMKDGWTVKTKDRNLSAQYEHT 237 Query: 243 VLVTETGFEVLTVSPGMPAP 262 ++VT+ G E++T+ P Sbjct: 238 IVVTDNGCEIMTLRKDDTIP 257