BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0104.p (262 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1408 [I] COG0020 Undecaprenyl pyrophosphate synthase Rso Rals... 353 3e-97 NMA0081 [I] COG0020 Undecaprenyl pyrophosphate synthase NmA Neis... 319 5e-87 NMB0186 [I] COG0020 Undecaprenyl pyrophosphate synthase Nme Neis... 317 1e-86 PA3652 [I] COG0020 Undecaprenyl pyrophosphate synthase Pae Pseud... 296 2e-80 HI0920 [I] COG0020 Undecaprenyl pyrophosphate synthase Hin Haemo... 262 7e-70 VC2256 [I] COG0020 Undecaprenyl pyrophosphate synthase Vch Vibri... 257 2e-68 FN1326 [I] COG0020 Undecaprenyl pyrophosphate synthase Fnu Fusob... 248 7e-66 YPO1049 [I] COG0020 Undecaprenyl pyrophosphate synthase Ype Yers... 245 7e-65 yaeS [I] COG0020 Undecaprenyl pyrophosphate synthase Eco Escheri... 244 1e-64 ZyaeS [I] COG0020 Undecaprenyl pyrophosphate synthase EcZ Escher... 244 1e-64 >RSc1408 [I] COG0020 Undecaprenyl pyrophosphate synthase Rso Ralstonia solanacearum Length = 258 Score = 353 bits (905), Expect = 3e-97, Method: Compositional matrix adjust. Identities = 163/245 (66%), Positives = 202/245 (82%), Gaps = 2/245 (0%) Query: 3 HQSSTLAVPETSAVPRHVAIIMDGNGRWATKRFLPRVAGHAKGVDAVRSIVEACAERGIE 62 H SSTLAVP+T+ P HVAIIMDGNGRWAT+R LPR+AGH++G+DAVR+ V+A RG+ Sbjct: 2 HISSTLAVPDTADTPHHVAIIMDGNGRWATERHLPRMAGHSRGLDAVRAAVQAADHRGVR 61 Query: 63 FLTLFAFSSENWRRPADEVSVLMRLFMTVLEREVGKMAANGIRLKIVGDMSRFDPKLQEM 122 +LTLFAFSSENWRRPA+E+S LM+LFMT L REV K+ +GIRL++VGD+S F P++Q M Sbjct: 62 YLTLFAFSSENWRRPAEEISFLMKLFMTALRREVSKLNDSGIRLRVVGDLSAFSPRIQLM 121 Query: 123 AAKAEAQTAANSRLTLTVCANYGGRWDVMQAVSKMIKDKPGHAD--FTEEELAPYLAMAY 180 +AEA+TA N LT+T+ ANYGGRWD++QA+ ++ D+P A TEE L+PY+A+AY Sbjct: 122 IREAEAKTATNPGLTVTIAANYGGRWDILQAMRALVADQPDIAPEAITEEALSPYMALAY 181 Query: 181 APEPDLFIRTGGEQRISNFLLWQLAYSELYFTETFWPDFDAKALDLAIASYQQRERRFGR 240 A EPDLFIRTGGEQRISNF+LWQLAYSELYFTE +WPDFDA +D A A Y+ RERRFGR Sbjct: 182 ASEPDLFIRTGGEQRISNFMLWQLAYSELYFTERYWPDFDAAEMDRAFAWYRNRERRFGR 241 Query: 241 TSAQV 245 TSAQ+ Sbjct: 242 TSAQL 246 >NMA0081 [I] COG0020 Undecaprenyl pyrophosphate synthase NmA Neisseria meningitidis Z2491 Length = 248 Score = 319 bits (817), Expect = 5e-87, Method: Compositional matrix adjust. Identities = 143/242 (59%), Positives = 195/242 (80%), Gaps = 2/242 (0%) Query: 4 QSSTLAVPETSAVPRHVAIIMDGNGRWATKRFLPRVAGHAKGVDAVRSIVEACAERGIEF 63 +SST AV E +A+P+H+A+IMDGNGRWA KRFLPR+ GH +G+DA+ ++V+ CA+ G+++ Sbjct: 2 KSSTQAVLEHTAIPKHIAVIMDGNGRWAKKRFLPRIMGHKRGLDALENMVKHCAKLGVQY 61 Query: 64 LTLFAFSSENWRRPADEVSVLMRLFMTVLEREVGKMAANGIRLKIVGDMSRFDPKLQEMA 123 LT+FAFS+ENWRRP DEVS LM LF+ L+++V ++ N +RLKI+G RF+ ++ + Sbjct: 62 LTVFAFSTENWRRPEDEVSFLMGLFLQALQKQVRRLHENNMRLKILGSRERFNRQILKGI 121 Query: 124 AKAEAQTAANSRLTLTVCANYGGRWDVMQAVSKMIKDKPGHADFTEEELAPYLAMAYAPE 183 +AEA TA N+ LTL++ A+YGGRWD++QA +K+I + G ++ TE+ LA YL + APE Sbjct: 122 EEAEALTANNTGLTLSIAADYGGRWDILQAANKLIAE--GVSEITEDTLAKYLMLGDAPE 179 Query: 184 PDLFIRTGGEQRISNFLLWQLAYSELYFTETFWPDFDAKALDLAIASYQQRERRFGRTSA 243 PDLFIRTGGE RISNFLLWQ+AY+ELYFT+ WPDFD KALD A+AS+Q+RERRFGRTS Sbjct: 180 PDLFIRTGGETRISNFLLWQMAYAELYFTDILWPDFDGKALDDAVASFQKRERRFGRTSE 239 Query: 244 QV 245 Q+ Sbjct: 240 QL 241 >NMB0186 [I] COG0020 Undecaprenyl pyrophosphate synthase Nme Neisseria meningitidis MC58 Length = 248 Score = 317 bits (813), Expect = 1e-86, Method: Compositional matrix adjust. Identities = 142/242 (58%), Positives = 195/242 (80%), Gaps = 2/242 (0%) Query: 4 QSSTLAVPETSAVPRHVAIIMDGNGRWATKRFLPRVAGHAKGVDAVRSIVEACAERGIEF 63 +SST AV E +A+P+H+A+IMDGNGRWA KRFLPR+ GH +G+DA+ ++V+ CA+ G+++ Sbjct: 2 KSSTQAVLEHTAIPKHIAVIMDGNGRWAKKRFLPRIMGHKRGLDALENMVKHCAKLGVQY 61 Query: 64 LTLFAFSSENWRRPADEVSVLMRLFMTVLEREVGKMAANGIRLKIVGDMSRFDPKLQEMA 123 LT+FAFS+ENWRRP DEVS LM LF+ L+++V ++ N +RLKI+G RF+ ++ + Sbjct: 62 LTVFAFSTENWRRPEDEVSFLMGLFLQALQKQVRRLHENNMRLKILGSRERFNRQILQGI 121 Query: 124 AKAEAQTAANSRLTLTVCANYGGRWDVMQAVSKMIKDKPGHADFTEEELAPYLAMAYAPE 183 +AEA TA N+ LTL++ A+YGGRWD++QA +K+I + G ++ TE+ LA +L + APE Sbjct: 122 EEAEALTANNTGLTLSIAADYGGRWDILQAANKLIAE--GVSEITEDTLAKHLMLGDAPE 179 Query: 184 PDLFIRTGGEQRISNFLLWQLAYSELYFTETFWPDFDAKALDLAIASYQQRERRFGRTSA 243 PDLFIRTGGE RISNFLLWQ+AY+ELYFT+ WPDFD KALD A+AS+Q+RERRFGRTS Sbjct: 180 PDLFIRTGGETRISNFLLWQMAYAELYFTDILWPDFDGKALDDAVASFQKRERRFGRTSE 239 Query: 244 QV 245 Q+ Sbjct: 240 QL 241 >PA3652 [I] COG0020 Undecaprenyl pyrophosphate synthase Pae Pseudomonas aeruginosa Length = 251 Score = 296 bits (759), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 142/235 (60%), Positives = 173/235 (73%), Gaps = 4/235 (1%) Query: 15 AVPRHVAIIMDGNGRWATKRFLPRVAGHAKGVDAVRSIVEACAERGIEFLTLFAFSSENW 74 VPRHVAIIMDGN RWA KR LP VAGH GVDAVR+++E CAE G+E LTLFAFSSENW Sbjct: 9 CVPRHVAIIMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAGVEVLTLFAFSSENW 68 Query: 75 RRPADEVSVLMRLFMTVLEREVGKMAANGIRLKIVGDMSRFDPKLQEMAAKAEAQTAANS 134 +RPADEVS LM LF+ L REV K+ NGIRL+I+GD +RF P+LQ +AEA TA N+ Sbjct: 69 QRPADEVSALMELFLVALRREVRKLDENGIRLRIIGDRTRFHPELQAAMREAEAATAGNT 128 Query: 135 RLTLTVCANYGGRWDVMQAVSKMIKD-KPGHA---DFTEEELAPYLAMAYAPEPDLFIRT 190 R L V ANYGG+WD++QA ++ ++ + GH D + E L L P PDL IRT Sbjct: 129 RFLLQVAANYGGQWDIVQAAQRLAREVQGGHLAADDISAELLQGCLVTGDQPLPDLCIRT 188 Query: 191 GGEQRISNFLLWQLAYSELYFTETFWPDFDAKALDLAIASYQQRERRFGRTSAQV 245 GGE RISNFLLWQLAY+ELYF++ FWPDF A+ A+A + +R+RRFG+TS QV Sbjct: 189 GGEHRISNFLLWQLAYAELYFSDLFWPDFKHAAMRAALADFSKRQRRFGKTSEQV 243 >HI0920 [I] COG0020 Undecaprenyl pyrophosphate synthase Hin Haemophilus influenzae Length = 239 Score = 262 bits (669), Expect = 7e-70, Method: Compositional matrix adjust. Identities = 126/234 (53%), Positives = 156/234 (66%), Gaps = 4/234 (1%) Query: 12 ETSAVPRHVAIIMDGNGRWATKRFLPRVAGHAKGVDAVRSIVEACAERGIEFLTLFAFSS 71 + + +P+HVAIIMDGNGRWA ++ R+ GH GV AVR V + G+E LTL+AFSS Sbjct: 5 DQTNIPKHVAIIMDGNGRWAKQKNKMRIFGHTNGVTAVRKAVAYARQIGVEVLTLYAFSS 64 Query: 72 ENWRRPADEVSVLMRLFMTVLEREVGKMAANGIRLKIVGDMSRFDPKLQEMAAKAEAQTA 131 ENW RP E+S LM LFM L+REV K+ N I LKI+GD+SRF LQE KAE T Sbjct: 65 ENWSRPEQEISALMSLFMQALDREVKKLHKNNICLKIIGDVSRFSETLQEKIKKAENLTE 124 Query: 132 ANSRLTLTVCANYGGRWDVMQAVS----KMIKDKPGHADFTEEELAPYLAMAYAPEPDLF 187 N+ LTL + ANYGG WD++QA K+ K++ +D +LA AP DL Sbjct: 125 KNTALTLNIAANYGGCWDIIQAAKQIAEKVKKEEMSVSDINNSTFQHHLATQNAPPVDLL 184 Query: 188 IRTGGEQRISNFLLWQLAYSELYFTETFWPDFDAKALDLAIASYQQRERRFGRT 241 IRT GEQRISNFLLWQ+AY+ELYF++ WPDF+ + AIASYQQR RRFG T Sbjct: 185 IRTSGEQRISNFLLWQIAYAELYFSDVLWPDFNQLEFNRAIASYQQRHRRFGGT 238 >VC2256 [I] COG0020 Undecaprenyl pyrophosphate synthase Vch Vibrio cholerae Length = 256 Score = 257 bits (656), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 121/235 (51%), Positives = 159/235 (67%), Gaps = 4/235 (1%) Query: 15 AVPRHVAIIMDGNGRWATKRFLPRVAGHAKGVDAVRSIVEACAERGIEFLTLFAFSSENW 74 +P+H+A+IMDGNGRWA + PRV GH GV AVR + A GI+ +TLFAFSSENW Sbjct: 16 VLPKHIAVIMDGNGRWAKAQGKPRVFGHKNGVAAVRKTISTSARLGIKAVTLFAFSSENW 75 Query: 75 RRPADEVSVLMRLFMTVLEREVGKMAANGIRLKIVGDMSRFDPKLQEMAAKAEAQTAANS 134 RRP +EV VLM LFMTVL E+ K+ N +RL+++GD SRF +LQ A+AE TA+N+ Sbjct: 76 RRPEEEVGVLMELFMTVLSTEIKKLHKNNLRLRVIGDKSRFSERLQTKIAQAEQLTASNT 135 Query: 135 RLTLTVCANYGGRWDVMQAVS----KMIKDKPGHADFTEEELAPYLAMAYAPEPDLFIRT 190 + + + ANYGG+WD++QA K+ + + +D E+ +L MA P+ DL IRT Sbjct: 136 GMVVNIAANYGGQWDILQATQALAEKVTQGELQPSDIDEDVFKQHLTMADLPDVDLLIRT 195 Query: 191 GGEQRISNFLLWQLAYSELYFTETFWPDFDAKALDLAIASYQQRERRFGRTSAQV 245 GE RISNF+LWQLAY+E+YFT FWP+FD L A+ + RERRFG T QV Sbjct: 196 SGECRISNFMLWQLAYAEMYFTPVFWPEFDENCLIEAVTWFVNRERRFGCTGEQV 250 >FN1326 [I] COG0020 Undecaprenyl pyrophosphate synthase Fnu Fusobacterium nucleatum Length = 230 Score = 248 bits (634), Expect = 7e-66, Method: Compositional matrix adjust. Identities = 115/224 (51%), Positives = 152/224 (67%), Gaps = 3/224 (1%) Query: 16 VPRHVAIIMDGNGRWATKRFLPRVAGHAKGVDAVRSIVEACAERGIEFLTLFAFSSENWR 75 +P+H+AIIMDGNGRWA KR L R GH +G +R +E E G+++LT++AFS+ENW Sbjct: 5 IPKHIAIIMDGNGRWAKKRGLARSFGHMEGAKTLRKALEYLTEIGVKYLTVYAFSTENWN 64 Query: 76 RPADEVSVLMRLFMTVLEREVGKMAANGIRLKIVGDMSRFDPKLQEMAAKAEAQTAANSR 135 RP DEVS LM+LF+ ++ E M N IR + G + KLQ+ K E +T N + Sbjct: 65 RPQDEVSTLMKLFLKYIKNERKNMMKNKIRFFVSGRKNNVPEKLQKEIEKLEEETKNNDK 124 Query: 136 LTLTVCANYGGRWDVMQAVSKMIKDKPGHADFTEEELAPYLAMAYAPEPDLFIRTGGEQR 195 +TL + NYG R +++ AV+++IKD G + TEE+ + YL + P+PDL IRT GE R Sbjct: 125 ITLNIAFNYGSRAEIVDAVNRIIKD--GKENITEEDFSKYLYNDF-PDPDLVIRTSGEMR 181 Query: 196 ISNFLLWQLAYSELYFTETFWPDFDAKALDLAIASYQQRERRFG 239 ISNFLLWQ+AYSELY T+ WPDFD K +D AI SY QRERRFG Sbjct: 182 ISNFLLWQIAYSELYITDVLWPDFDEKEIDKAIESYNQRERRFG 225 >YPO1049 [I] COG0020 Undecaprenyl pyrophosphate synthase Ype Yersinia pestis Length = 252 Score = 245 bits (626), Expect = 7e-65, Method: Compositional matrix adjust. Identities = 117/230 (50%), Positives = 151/230 (65%), Gaps = 4/230 (1%) Query: 17 PRHVAIIMDGNGRWATKRFLPRVAGHAKGVDAVRSIVEACAERGIEFLTLFAFSSENWRR 76 PRHVAIIMDGNGRWA + RV GH GV +VR V A+ ++ LTL+AFSSENW R Sbjct: 16 PRHVAIIMDGNGRWAKNKGKLRVFGHKAGVKSVRRAVSFAAKHNLDALTLYAFSSENWNR 75 Query: 77 PADEVSVLMRLFMTVLEREVGKMAANGIRLKIVGDMSRFDPKLQEMAAKAEAQTAANSRL 136 P EV+ LM LF+ L+ EV + + +RL I+GD+SRF +LQE ++E TA N L Sbjct: 76 PDQEVTALMELFVRALDSEVKSLHKHNVRLSIIGDISRFSGRLQERIRRSEKLTANNDGL 135 Query: 137 TLTVCANYGGRWDVMQAVSKMI----KDKPGHADFTEEELAPYLAMAYAPEPDLFIRTGG 192 L + ANYGGRWD++Q V + K + D +EE L Y+ + + DL IRTGG Sbjct: 136 KLNIAANYGGRWDIIQGVRHLAEQVQKGELQPTDISEESLNSYICLHEQSQVDLVIRTGG 195 Query: 193 EQRISNFLLWQLAYSELYFTETFWPDFDAKALDLAIASYQQRERRFGRTS 242 E RISNFLLWQ+AY+ELYFT+ WPDFD + A+ ++ QRERRFG T+ Sbjct: 196 EHRISNFLLWQIAYAELYFTDVLWPDFDENVFEGALNAFAQRERRFGGTT 245 >yaeS [I] COG0020 Undecaprenyl pyrophosphate synthase Eco Escherichia coli K12 Length = 253 Score = 244 bits (623), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 122/230 (53%), Positives = 153/230 (66%), Gaps = 8/230 (3%) Query: 18 RHVAIIMDGNGRWATKRFLPRVAGHAKGVDAVRSIVEACAERGIEFLTLFAFSSENWRRP 77 RHVAIIMDGNGRWA K+ R GH G +VR V A GIE LTL+AFSSENW RP Sbjct: 19 RHVAIIMDGNGRWAKKQGKIRAFGHKAGAKSVRRAVSFAANNGIEALTLYAFSSENWNRP 78 Query: 78 ADEVSVLMRLFMTVLEREVGKMAANGIRLKIVGDMSRFDPKLQEMAAKAEAQTAANSRLT 137 A EVS LM LF+ L+ EV + + +RL+I+GD SRF+ +LQE K+EA TA N+ LT Sbjct: 79 AQEVSALMELFVWALDSEVKSLHRHNVRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLT 138 Query: 138 LTVCANYGGRWDVMQAVSKMIKD------KPGHADFTEEELAPYLAMAYAPEPDLFIRTG 191 L + ANYGGRWD++Q V ++ + +P D EE L ++ M DL IRTG Sbjct: 139 LNIAANYGGRWDIVQGVRQLAEKVQQGNLQPDQID--EEMLNQHVCMHELAPVDLVIRTG 196 Query: 192 GEQRISNFLLWQLAYSELYFTETFWPDFDAKALDLAIASYQQRERRFGRT 241 GE RISNFLLWQ+AY+ELYFT+ WPDFD + + A+ ++ RERRFG T Sbjct: 197 GEHRISNFLLWQIAYAELYFTDVLWPDFDEQDFEGALNAFANRERRFGGT 246 >ZyaeS [I] COG0020 Undecaprenyl pyrophosphate synthase EcZ Escherichia coli O157:H7 EDL933 Length = 253 Score = 244 bits (623), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 122/230 (53%), Positives = 153/230 (66%), Gaps = 8/230 (3%) Query: 18 RHVAIIMDGNGRWATKRFLPRVAGHAKGVDAVRSIVEACAERGIEFLTLFAFSSENWRRP 77 RHVAIIMDGNGRWA K+ R GH G +VR V A GIE LTL+AFSSENW RP Sbjct: 19 RHVAIIMDGNGRWAKKQGKIRAFGHKAGAKSVRRAVSFAANNGIEALTLYAFSSENWNRP 78 Query: 78 ADEVSVLMRLFMTVLEREVGKMAANGIRLKIVGDMSRFDPKLQEMAAKAEAQTAANSRLT 137 A EVS LM LF+ L+ EV + + +RL+I+GD SRF+ +LQE K+EA TA N+ LT Sbjct: 79 AQEVSALMELFVWALDSEVKSLHRHNVRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLT 138 Query: 138 LTVCANYGGRWDVMQAVSKMIKD------KPGHADFTEEELAPYLAMAYAPEPDLFIRTG 191 L + ANYGGRWD++Q V ++ + +P D EE L ++ M DL IRTG Sbjct: 139 LNIAANYGGRWDIVQGVRQLAEKVQQGNLQPDQID--EEMLNQHVCMHELAPVDLVIRTG 196 Query: 192 GEQRISNFLLWQLAYSELYFTETFWPDFDAKALDLAIASYQQRERRFGRT 241 GE RISNFLLWQ+AY+ELYFT+ WPDFD + + A+ ++ RERRFG T Sbjct: 197 GEHRISNFLLWQIAYAELYFTDVLWPDFDEQDFEGALNAFANRERRFGGT 246