BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0073.p (179 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1451 [FJ] COG0590 Cytosine/adenosine deaminases Rso Ralstonia... 207 1e-53 yfhC [FJ] COG0590 Cytosine/adenosine deaminases Eco Escherichia ... 183 2e-46 ZyfhC [FJ] COG0590 Cytosine/adenosine deaminases EcZ Escherichia... 182 3e-46 ECs3425 [FJ] COG0590 Cytosine/adenosine deaminases Ecs Escherich... 182 3e-46 STM2568 [FJ] COG0590 Cytosine/adenosine deaminases Sty Salmonell... 180 1e-45 HI0906 [FJ] COG0590 Cytosine/adenosine deaminases Hin Haemophilu... 169 4e-42 PA3767 [FJ] COG0590 Cytosine/adenosine deaminases Pae Pseudomona... 168 6e-42 BH0033 [FJ] COG0590 Cytosine/adenosine deaminases Bha Bacillus h... 166 2e-41 PM0078 [FJ] COG0590 Cytosine/adenosine deaminases Pmu Pasteurell... 158 5e-39 NMB0933_2 [FJ] COG0590 Cytosine/adenosine deaminases Nme Neisser... 158 6e-39 >RSc1451 [FJ] COG0590 Cytosine/adenosine deaminases Rso Ralstonia solanacearum Length = 183 Score = 207 bits (527), Expect = 1e-53, Method: Compositional matrix adjust. Identities = 98/165 (59%), Positives = 125/165 (75%) Query: 1 VPSASAAAGEADLLHMRAALEQARHAWALGEVPVGAVVVKDGVVIATGFNQPIGKHDPTA 60 P +A E D M+ AL QAR AW GEVPVGAVVV+ ++ G+N PIG HDP+A Sbjct: 8 TPPPGMSAHERDGYWMQQALVQARLAWGEGEVPVGAVVVRGNEIVGVGYNAPIGTHDPSA 67 Query: 61 HAEIMALRRAAEILGNYRLPGCELYVTLEPCVMCSGAMMHARLARVVFGAADPKTGACGS 120 HAE+ ALR+AA LGNYRLP CE++VTLEPCVMC+GAM+HAR+ARVV+GA DPKTGA GS Sbjct: 68 HAEMRALRQAAVRLGNYRLPECEVFVTLEPCVMCAGAMLHARVARVVYGAPDPKTGAAGS 127 Query: 121 VLNLFEQEQLNHHTALLGGVMAEECGQLLKDFFAMRREQLKQQRL 165 VL+LF + +LNH TA++G V+A++CG +L+ FFA RR + R+ Sbjct: 128 VLDLFAETRLNHQTAIIGSVLAQDCGDMLRAFFAERRASQRAARM 172 >yfhC [FJ] COG0590 Cytosine/adenosine deaminases Eco Escherichia coli K12 Length = 178 Score = 183 bits (465), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 84/149 (56%), Positives = 110/149 (73%) Query: 16 MRAALEQARHAWALGEVPVGAVVVKDGVVIATGFNQPIGKHDPTAHAEIMALRRAAEILG 75 MR AL A+ AW EVPVGAV+V + VI G+N+PIG+HDPTAHAEIMALR+ ++ Sbjct: 23 MRHALTLAKRAWDEREVPVGAVLVHNNRVIGEGWNRPIGRHDPTAHAEIMALRQGGLVMQ 82 Query: 76 NYRLPGCELYVTLEPCVMCSGAMMHARLARVVFGAADPKTGACGSVLNLFEQEQLNHHTA 135 NYRL LYVTLEPCVMC+GAM+H+R+ RVVFGA D KTGA GS++++ +NH Sbjct: 83 NYRLIDATLYVTLEPCVMCAGAMIHSRIGRVVFGARDAKTGAAGSLMDVLHHPGMNHRVE 142 Query: 136 LLGGVMAEECGQLLKDFFAMRREQLKQQR 164 + G++A+EC LL DFF MRR+++K Q+ Sbjct: 143 ITEGILADECAALLSDFFRMRRQEIKAQK 171 >ZyfhC [FJ] COG0590 Cytosine/adenosine deaminases EcZ Escherichia coli O157:H7 EDL933 Length = 178 Score = 182 bits (463), Expect = 3e-46, Method: Compositional matrix adjust. Identities = 83/149 (55%), Positives = 110/149 (73%) Query: 16 MRAALEQARHAWALGEVPVGAVVVKDGVVIATGFNQPIGKHDPTAHAEIMALRRAAEILG 75 MR A+ A+ AW EVPVGAV+V + VI G+N+PIG+HDPTAHAEIMALR+ ++ Sbjct: 23 MRHAMTLAKRAWDEREVPVGAVLVHNNRVIGEGWNRPIGRHDPTAHAEIMALRQGGLVMQ 82 Query: 76 NYRLPGCELYVTLEPCVMCSGAMMHARLARVVFGAADPKTGACGSVLNLFEQEQLNHHTA 135 NYRL LYVTLEPCVMC+GAM+H+R+ RVVFGA D KTGA GS++++ +NH Sbjct: 83 NYRLIDATLYVTLEPCVMCAGAMIHSRIGRVVFGARDAKTGAAGSLMDVLHHPGMNHRVE 142 Query: 136 LLGGVMAEECGQLLKDFFAMRREQLKQQR 164 + G++A+EC LL DFF MRR+++K Q+ Sbjct: 143 ITEGILADECAALLSDFFRMRRQEIKAQK 171 >ECs3425 [FJ] COG0590 Cytosine/adenosine deaminases Ecs Escherichia coli O157:H7 Length = 178 Score = 182 bits (463), Expect = 3e-46, Method: Compositional matrix adjust. Identities = 83/149 (55%), Positives = 110/149 (73%) Query: 16 MRAALEQARHAWALGEVPVGAVVVKDGVVIATGFNQPIGKHDPTAHAEIMALRRAAEILG 75 MR A+ A+ AW EVPVGAV+V + VI G+N+PIG+HDPTAHAEIMALR+ ++ Sbjct: 23 MRHAMTLAKRAWDEREVPVGAVLVHNNRVIGEGWNRPIGRHDPTAHAEIMALRQGGLVMQ 82 Query: 76 NYRLPGCELYVTLEPCVMCSGAMMHARLARVVFGAADPKTGACGSVLNLFEQEQLNHHTA 135 NYRL LYVTLEPCVMC+GAM+H+R+ RVVFGA D KTGA GS++++ +NH Sbjct: 83 NYRLIDATLYVTLEPCVMCAGAMIHSRIGRVVFGARDAKTGAAGSLMDVLHHPGMNHRVE 142 Query: 136 LLGGVMAEECGQLLKDFFAMRREQLKQQR 164 + G++A+EC LL DFF MRR+++K Q+ Sbjct: 143 ITEGILADECAALLSDFFRMRRQEIKAQK 171 >STM2568 [FJ] COG0590 Cytosine/adenosine deaminases Sty Salmonella typhimurium LT2 Length = 183 Score = 180 bits (457), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 84/146 (57%), Positives = 108/146 (73%) Query: 16 MRAALEQARHAWALGEVPVGAVVVKDGVVIATGFNQPIGKHDPTAHAEIMALRRAAEILG 75 MR AL A+ AW EVPVGAV+V + VI G+N+PIG+HDPTAHAEIMALR+ +L Sbjct: 23 MRHALTLAKRAWDEREVPVGAVLVHNHRVIGEGWNRPIGRHDPTAHAEIMALRQGGLVLQ 82 Query: 76 NYRLPGCELYVTLEPCVMCSGAMMHARLARVVFGAADPKTGACGSVLNLFEQEQLNHHTA 135 NYRL LYVTLEPCVMC+GAM+H+R+ RVVFGA D KTGA GS++++ +NH Sbjct: 83 NYRLLDTTLYVTLEPCVMCAGAMVHSRIGRVVFGARDAKTGAAGSLIDVLHHPGMNHRVE 142 Query: 136 LLGGVMAEECGQLLKDFFAMRREQLK 161 ++ GV+ +EC LL DFF MRR+++K Sbjct: 143 IIEGVLRDECATLLSDFFRMRRQEIK 168 >HI0906 [FJ] COG0590 Cytosine/adenosine deaminases Hin Haemophilus influenzae Length = 173 Score = 169 bits (427), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 84/163 (51%), Positives = 109/163 (66%), Gaps = 1/163 (0%) Query: 3 SASAAAGEADLLHMRAALEQARHAWALGEVPVGAVVVKDGV-VIATGFNQPIGKHDPTAH 61 A+ E D MR ALE A A ALGE+PVGAV+V D +I G+N I + DPTAH Sbjct: 2 DAAKVRSEFDEKMMRYALELADKAEALGEIPVGAVLVDDARNIIGEGWNLSIVQSDPTAH 61 Query: 62 AEIMALRRAAEILGNYRLPGCELYVTLEPCVMCSGAMMHARLARVVFGAADPKTGACGSV 121 AEI+ALR A+ + NYRL LYVTLEPC MC+GA++H+R+ R+VFGA+D KTGA GS Sbjct: 62 AEIIALRNGAKNIQNYRLLNSTLYVTLEPCTMCAGAILHSRIKRLVFGASDYKTGAIGSR 121 Query: 122 LNLFEQEQLNHHTALLGGVMAEECGQLLKDFFAMRREQLKQQR 164 + F+ ++NH + GV+AEEC Q L FF RRE+ K ++ Sbjct: 122 FHFFDDYKMNHTLEVTSGVLAEECSQKLSTFFQKRREEKKIEK 164 >PA3767 [FJ] COG0590 Cytosine/adenosine deaminases Pae Pseudomonas aeruginosa Length = 182 Score = 168 bits (425), Expect = 6e-42, Method: Compositional matrix adjust. Identities = 78/133 (58%), Positives = 97/133 (72%) Query: 32 VPVGAVVVKDGVVIATGFNQPIGKHDPTAHAEIMALRRAAEILGNYRLPGCELYVTLEPC 91 VPVGAV+V++G +I GFN+PI HDP+AHAE++A+R AA GNYRLPG LYVTLEPC Sbjct: 48 VPVGAVLVREGEIIGRGFNRPISSHDPSAHAEMLAIRMAAAEAGNYRLPGSTLYVTLEPC 107 Query: 92 VMCSGAMMHARLARVVFGAADPKTGACGSVLNLFEQEQLNHHTALLGGVMAEECGQLLKD 151 MCSG ++HAR+ R+V+G +PK+GA S FEQE LNH + GGV+AEEC Q L Sbjct: 108 SMCSGLLVHARIQRLVYGTVEPKSGAVESRGRFFEQEHLNHRVMVEGGVLAEECSQALSA 167 Query: 152 FFAMRREQLKQQR 164 FF RRE K+ R Sbjct: 168 FFRARREAAKKPR 180 >BH0033 [FJ] COG0590 Cytosine/adenosine deaminases Bha Bacillus halodurans Length = 159 Score = 166 bits (420), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 78/151 (51%), Positives = 104/151 (68%) Query: 12 DLLHMRAALEQARHAWALGEVPVGAVVVKDGVVIATGFNQPIGKHDPTAHAEIMALRRAA 71 DL +MR AL QA A LGEVP+GAV+VKDGVV+A +N AHAE++A+ +A Sbjct: 5 DLYYMREALVQADEAERLGEVPIGAVIVKDGVVVAKAYNLREINQQAIAHAELLAIEKAC 64 Query: 72 EILGNYRLPGCELYVTLEPCVMCSGAMMHARLARVVFGAADPKTGACGSVLNLFEQEQLN 131 + LG +RL GC LYVTLEPC MC+GA++ +R+ RVV+GA DPK G G+++NL +E+ N Sbjct: 65 KALGTWRLTGCTLYVTLEPCPMCAGAIVQSRIERVVYGATDPKAGCAGTLMNLLNEERFN 124 Query: 132 HHTALLGGVMAEECGQLLKDFFAMRREQLKQ 162 H T + GV+ EEC Q L FF RE+ K+ Sbjct: 125 HQTIVESGVLEEECSQRLTAFFRKLRERKKR 155 >PM0078 [FJ] COG0590 Cytosine/adenosine deaminases Pmu Pasteurella multocida Length = 166 Score = 158 bits (400), Expect = 5e-39, Method: Compositional matrix adjust. Identities = 78/154 (50%), Positives = 103/154 (66%), Gaps = 1/154 (0%) Query: 9 GEADLLHMRAALEQARHAWALGEVPVGAVVVKD-GVVIATGFNQPIGKHDPTAHAEIMAL 67 + D MR AL A A LGE+PVGAV+V + G ++ G+N I + DPTAHAEI+AL Sbjct: 3 SDMDEKWMRHALRLADKAEQLGEIPVGAVLVDEQGNLLGEGWNLSISESDPTAHAEIVAL 62 Query: 68 RRAAEILGNYRLPGCELYVTLEPCVMCSGAMMHARLARVVFGAADPKTGACGSVLNLFEQ 127 R+ + L NYRL LYVTLEPC MC+GA++H+R+ R+VFGA+D KTGA GS + F+ Sbjct: 63 RQGGQRLQNYRLLNTTLYVTLEPCTMCAGAILHSRIKRLVFGASDYKTGAVGSRFHFFDD 122 Query: 128 EQLNHHTALLGGVMAEECGQLLKDFFAMRREQLK 161 ++NH + GV+ EEC Q + FF RREQ K Sbjct: 123 YKMNHAIEITAGVLQEECSQKISAFFQKRREQQK 156 >NMB0933_2 [FJ] COG0590 Cytosine/adenosine deaminases Nme Neisseria meningitidis MC58 Length = 152 Score = 158 bits (399), Expect = 6e-39, Method: Compositional matrix adjust. Identities = 73/143 (51%), Positives = 102/143 (71%) Query: 16 MRAALEQARHAWALGEVPVGAVVVKDGVVIATGFNQPIGKHDPTAHAEIMALRRAAEILG 75 M AL QA + A GE+PVGAV+V DG +IA+ N I + + HAEI AL +A + Sbjct: 9 MCEALRQAEQSSADGEIPVGAVIVSDGKIIASAHNTCIADCNVSRHAEINALAQAGREIQ 68 Query: 76 NYRLPGCELYVTLEPCVMCSGAMMHARLARVVFGAADPKTGACGSVLNLFEQEQLNHHTA 135 NYRL GC++Y+TLEPC MC+ A++ AR+ RV++GAA+PKTGA GS++NLF ++LN HTA Sbjct: 69 NYRLDGCDIYITLEPCAMCASALIQARIRRVIYGAAEPKTGAAGSIVNLFADKRLNTHTA 128 Query: 136 LLGGVMAEECGQLLKDFFAMRRE 158 + GG++ EEC +L FF +R+ Sbjct: 129 IRGGILQEECRAVLSRFFQNKRK 151