BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0067.p (758 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3339_1 [R] COG1752 Predicted esterase of the alpha-beta hydrol... 216 1e-55 VC0603_1 [R] COG1752 Predicted esterase of the alpha-beta hydrol... 205 4e-52 BS_ylbK [R] COG1752 Predicted esterase of the alpha-beta hydrola... 152 4e-36 FN1704_1 [R] COG1752 Predicted esterase of the alpha-beta hydrol... 149 2e-35 BH2587 [R] COG1752 Predicted esterase of the alpha-beta hydrolas... 131 6e-30 XF0066 [R] COG1752 Predicted esterase of the alpha-beta hydrolas... 129 2e-29 NMB2139 [R] COG1752 Predicted esterase of the alpha-beta hydrola... 127 9e-29 NMA0225 [R] COG1752 Predicted esterase of the alpha-beta hydrola... 126 2e-28 TP1033 Non COG 123 2e-27 PA3339_2 [M] COG0729 Outer membrane protein Pae Pseudomonas aeru... 122 3e-27 >PA3339_1 [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily Pae Pseudomonas aeruginosa Length = 308 Score = 216 bits (551), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 130/288 (45%), Positives = 179/288 (62%), Gaps = 3/288 (1%) Query: 41 RPRVCLVLSGGGARGYAHLGVLQYLEQLHIPIDCIAGTSMGALIGGLYASGLDAGELERR 100 RP++ LVLSGG ARG AH+GVL+ L++ I ID IAGTSMGA++GGLYASG ELER Sbjct: 22 RPKIGLVLSGGAARGLAHIGVLKALDEQGIQIDAIAGTSMGAVVGGLYASGYTPAELERI 81 Query: 101 LAATNLSDIAFDRNERSRLPQAQREDEFQYPIS--ISAGLDGSKLKLASGLVQGNKLLAL 158 + D R +P +++D+ + + IS DG+ L L G++QG L + Sbjct: 82 ALEMDWQQALSDAPPRKDVPFRRKQDDRDFLVKQKISFRDDGT-LGLPLGVIQGQNLAMV 140 Query: 159 LQNWTAQLPANIDFARLPIPFRAVATDLSLGSEVVLDHGSLPRAMRASMAVPGLFAPFRI 218 L++ N DF +L IPFRAV+TD++ G +VV G LP+A+RASM++P +FAP I Sbjct: 141 LESLLVHTSDNRDFDKLAIPFRAVSTDIATGEKVVFRKGHLPQAIRASMSIPAVFAPVEI 200 Query: 219 DQRTLVDGGLVSNLPVQTARDMGADVVIAVNIATPLQDAAQLQSPTAVAQQMVGILIQQN 278 D R LVDGG+V N+PV ARDMG DVVI V+I PL+D L + V Q + ++ ++N Sbjct: 201 DGRLLVDGGMVDNIPVDVARDMGVDVVIVVDIGNPLRDRKDLSTVLDVMNQSITLMTRKN 260 Query: 279 VKAQKALLGAQDILIEPQMEGMSFTDFARGKDGVNAGWEAAQRQQARL 326 +AQ A L D+LI+P + G TDF R ++AG+ A ARL Sbjct: 261 SEAQLATLKPGDVLIQPPLSGYGTTDFGRVPQLIDAGYRATTVLAARL 308 >VC0603_1 [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily Vch Vibrio cholerae Length = 310 Score = 205 bits (521), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 118/286 (41%), Positives = 178/286 (62%) Query: 34 APAATQPRPRVCLVLSGGGARGYAHLGVLQYLEQLHIPIDCIAGTSMGALIGGLYASGLD 93 A A RP++ LVL+GGGA+G AH+GVL+ LE++H+P+D I GTSMGA +GGLYA+G+ Sbjct: 25 AQAQVAKRPKIALVLAGGGAKGAAHMGVLRALEEMHVPVDIITGTSMGAYVGGLYATGMS 84 Query: 94 AGELERRLAATNLSDIAFDRNERSRLPQAQREDEFQYPISISAGLDGSKLKLASGLVQGN 153 A E+E + + + + DR +RS+ +E E +Y I+ GL +++ G+VQG Sbjct: 85 AEEIEALIYSVDWNRGYRDRVDRSQRRVRDKEYEDRYQITTDLGLHWGEVRAPKGVVQGQ 144 Query: 154 KLLALLQNWTAQLPANIDFARLPIPFRAVATDLSLGSEVVLDHGSLPRAMRASMAVPGLF 213 +L +L+ T LPA F +L IP+RAVATD+ EVVLD G L AM ASM+VPG Sbjct: 145 NMLRMLRETTGNLPAFDSFDQLVIPYRAVATDIIHLQEVVLDKGFLVDAMMASMSVPGAL 204 Query: 214 APFRIDQRTLVDGGLVSNLPVQTARDMGADVVIAVNIATPLQDAAQLQSPTAVAQQMVGI 273 P+ ID LVDGG+ +N+PV+ AR MGAD++IAV+I+T + + VA Q+ Sbjct: 205 PPYEIDGLWLVDGGVTNNMPVEVARAMGADIIIAVDISTDYKSQEDFTNLFTVADQLSNY 264 Query: 274 LIQQNVKAQKALLGAQDILIEPQMEGMSFTDFARGKDGVNAGWEAA 319 L++++ + Q L ++D+L+ P + M +F + G++ A Sbjct: 265 LVRRSTERQSDHLTSRDLLLRPPVGKMETMEFDKMPAAFAMGYQEA 310 >BS_ylbK [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily Bsu Bacillus subtilis Length = 260 Score = 152 bits (383), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 97/286 (33%), Positives = 150/286 (52%), Gaps = 38/286 (13%) Query: 41 RPRVCLVLSGGGARGYAHLGVLQYLEQLHIPIDCIAGTSMGALIGGLYASGLDAGELERR 100 +P++ L L GGARG AHLGVL L + I +D IAG+SMGAL+G YA+G D +++ Sbjct: 3 KPKIGLALGSGGARGLAHLGVLSSLHKHQIEVDMIAGSSMGALVGSFYAAGHDVATMKKV 62 Query: 101 LAATNLSDIAFDRNERSRLPQAQREDEFQYPISISAGLDGSKLKLASGLVQGNKLLALLQ 160 A F R + ++ P KL G ++G+++ L+ Sbjct: 63 AKA-------FKRRLYA---------DYTVP------------KL--GFLKGDRVRQLVH 92 Query: 161 NWTAQLPANIDFARLPIPFRAVATDLSLGSEVVLDHGSLPRAMRASMAVPGLFAPFRIDQ 220 +T P L IP VA DL G ++V GS+ A+RAS+++PG+F P R+D Sbjct: 93 AYTFGKP----IEELQIPLGIVACDLQTGEKIVFRKGSVSDAVRASISIPGIFIPQRLDG 148 Query: 221 RTLVDGGLVSNLPVQTARDMGADVVIAVNIATPLQDAAQLQSPTAVAQQMVGILIQQNVK 280 R LVDG +V +PV +DMGAD++IA +++ + + + Q M IL + V+ Sbjct: 149 RLLVDGAVVDRIPVSVVKDMGADIIIASDVSRVRKTETAVHIFDVIMQSM-DILQNELVR 207 Query: 281 AQKALLGAQDILIEPQMEGMSFTDFARGKDGVNAGWEAAQRQQARL 326 Q A DI+I P +E S + FA ++ ++AG EA R +++ Sbjct: 208 HQTI---AADIMIRPSLETYSSSSFANIEEMISAGEEATNRMISKI 250 >FN1704_1 [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily Fnu Fusobacterium nucleatum Length = 375 Score = 149 bits (377), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 97/294 (32%), Positives = 154/294 (52%), Gaps = 11/294 (3%) Query: 36 AATQPRPRVCLVLSGGGARGYAHLGVLQYLEQLHIPIDCIAGTSMGALIGGLYASGLDAG 95 A +V LVLSGGG +GYAHLGVL+ LE+ +I ID I GTS+GA IG LY+ G Sbjct: 55 AKDNKNLKVALVLSGGGVKGYAHLGVLRVLERENIKIDYITGTSIGAFIGTLYSIGYTVD 114 Query: 96 ELERRLAATNLSDIAFDRNERSRLPQAQREDEFQYPISISAGLDGS-KLKLASGLVQGNK 154 E+E+ L N+S+ + + L ++E +Y + +S D GL + Sbjct: 115 EIEKFLDDVNVSNFLETITDNTNLSLEKKESLKKYSVHLS--FDNELNFSFPKGLRGTGE 172 Query: 155 LLALLQNWTAQLPANIDFARLPIPFRAVATDLSLGSEVVLDHGSLPRAMRASMAVPGLFA 214 LL+ + +F PIP R +AT+L+ G G + + + ASM++P +F Sbjct: 173 AYLLLKGLLGKYEHMDNFDNFPIPLRIIATNLNTGETKAFSKGDVAKILIASMSIPSIFE 232 Query: 215 PFRIDQRTLVDGGLVSNLPVQTARDMGADVVIAVNIATPL--QDAAQLQSPTAVAQQMVG 272 P +ID VDG + NLPV+ A +MGAD+V+A +I P+ +D + S A + Sbjct: 233 PMKIDGEIYVDGLVSRNLPVEEAYEMGADIVVASDIGAPVVEKDDYNILSVMNQASTIQA 292 Query: 273 ILIQQNVKAQKALLGAQDILIEPQMEGMSFTDFARGKDGVNAGWEAAQRQQARL 326 I + + +KA ILI P ++ +S D ++ ++ + G AA++Q ++ Sbjct: 293 SNITK-ISREKA-----SILISPDVKNISALDSSKKEELMKLGKVAAEKQIDKI 340 >BH2587 [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily Bha Bacillus halodurans Length = 275 Score = 131 bits (329), Expect = 6e-30, Method: Compositional matrix adjust. Identities = 85/243 (34%), Positives = 128/243 (52%), Gaps = 35/243 (14%) Query: 41 RPRVCLVLSGGGARGYAHLGVLQYLEQLHIPIDCIAGTSMGALIGGLYASGLDAGELERR 100 RP++ L L GGARGYAH+GVL+ LEQ IPID +AG+SMGAL+ LY +G L R Sbjct: 6 RPKIGLALGSGGARGYAHIGVLKVLEQEKIPIDYLAGSSMGALVASLYGAGHPTEHLIR- 64 Query: 101 LAATNLSDIAFDRNERSRLPQAQREDEFQYPISISAGLDGSKLKLASGLVQGNKLLALLQ 160 NL F R +F P G + G+++ L++ Sbjct: 65 --FANL----FKRKYYL---------DFTVP--------------KMGFIAGHRVEELIR 95 Query: 161 NWTAQLPANIDFARLPIPFRAVATDLSLGSEVVLDHGSLPRAMRASMAVPGLFAPFRIDQ 220 L L P R VA DL G V+L G + A+RAS+A+PG+F P I+ Sbjct: 96 ----VLAKKKRVEELDPPVRIVAADLLKGERVILQEGDVAEAVRASIAIPGIFVPKNIND 151 Query: 221 RTLVDGGLVSNLPVQTARDMGADVVIAVNIATPLQDAAQLQSPTAVAQQMVGILIQQNVK 280 R L+DGG++ +PV ++MGAD+ IAV++ T ++ +++S V Q + ++ ++ V+ Sbjct: 152 RLLIDGGVIDRVPVSVVKEMGADLTIAVDL-TIFREELEIRSVYDVILQTMDMMSKELVR 210 Query: 281 AQK 283 Q+ Sbjct: 211 VQE 213 >XF0066 [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily Xfa Xylella fastidiosa 9a5c Length = 395 Score = 129 bits (325), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 95/304 (31%), Positives = 153/304 (50%), Gaps = 46/304 (15%) Query: 7 ALLRTLLLALASVSLGGPAVAENSSTAAPAA--TQPRPRVCLVLSGGGARGYAHLGVLQY 64 + L T+++AL + P A S+ + + + P R+ + L GG A+G+AH+GVL+ Sbjct: 57 SFLATIVVALLTACSSAPRSASRLSSVSQLSDISLPPLRIGIALGGGAAKGFAHIGVLKM 116 Query: 65 LEQLHIPIDCIAGTSMGALIGGLYASGLDAGELERRLAATNLSDIAFDRNERSRLPQAQR 124 LE + +AGTS G+++G LYASG+D+ +++ + A + S+I R Sbjct: 117 LEANGLAPSVVAGTSAGSVVGALYASGMDSFKIQTKAVAMDESNI--------------R 162 Query: 125 EDEFQYPISISAGLDGSKLKLASGLVQGNKLLALLQNWTAQLPANIDFARLPIPFRAVAT 184 + F + GLVQG KL QN+ +L +L PF A+AT Sbjct: 163 DLRF----------------FSGGLVQGQKL----QNYVNELVGKRPIEKLNKPFGAIAT 202 Query: 185 DLSLGSEVVLDHGSLPRAMRASMAVPGLFAPFRIDQRTLVDGGLVSNLPVQTARDMGADV 244 L G + G++ A+RAS ++PG+F P I VDGG+ S +PV R +GAD Sbjct: 203 RLEDGQRTMFVRGNVGEAVRASCSIPGVFEPVTIGAYHYVDGGITSPVPVDAVRQLGADF 262 Query: 245 VIAVNIATPLQDAAQLQSP---TAVAQQMVGILIQQNVKAQKALLGAQDILIEPQMEGMS 301 VIAV+I++ A ++P Q + I+ Q +A+ L +I+I P++ + Sbjct: 263 VIAVDISSK----ATGKNPGGLVGTVNQSISIMGQHLGEAE---LKRANIVIHPKVLDIG 315 Query: 302 FTDF 305 TDF Sbjct: 316 STDF 319 >NMB2139 [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily Nme Neisseria meningitidis MC58 Length = 297 Score = 127 bits (319), Expect = 9e-29, Method: Compositional matrix adjust. Identities = 97/306 (31%), Positives = 150/306 (49%), Gaps = 52/306 (16%) Query: 20 SLGGPAVAENSSTAAPAATQPRPRVCLVLSGGGARGYAHLGVLQYLEQLHIPIDCIAGTS 79 + G AV + TA PAA V L L GG ++G+AH+G+++ L++ IP+ + GTS Sbjct: 24 TAGNNAVRKPVQTAKPAAV-----VGLALGGGASKGFAHVGIIKVLKENGIPVKVVTGTS 78 Query: 80 MGALIGGLYASGLDAGELERR---LAATNLSDIAFDRNERSRLPQAQREDEFQYPISISA 136 G+++G L+ASG+ LE L T+L D+ Sbjct: 79 AGSIVGSLFASGMSPDRLELEAEILGKTDLVDLTLS------------------------ 114 Query: 137 GLDGSKLKLASGLVQGNKLLALLQNWTAQLPANIDFARLPIPFRAVATDLSLGSEVVLDH 196 SG ++G KL QN+ + + PI F AVATD G V + Sbjct: 115 ---------TSGFIKGEKL----QNYINRKVGGRQIQQFPIKFAAVATDFETGKAVAFNQ 161 Query: 197 GSLPRAMRASMAVPGLFAPFRIDQRTLVDGGLVSNLPVQTARDMGADVVIAVNI-ATPLQ 255 G+ +A+RAS A+P +F P I + T VDGGL +PV AR GA+ VIAV+I A P + Sbjct: 162 GNAGQAVRASAAIPNVFQPVIIGRHTYVDGGLSQPVPVSAARRQGANFVIAVDISARPGK 221 Query: 256 DAAQLQSPTAVAQQMVGILIQQNVKAQKALLGAQDILIEPQMEGM-SFTDFARGKDGVNA 314 + + Q + Q + ++ +V A + LG D++I+PQ+ + + F + K + Sbjct: 222 NIS--QGFFSYLDQTLNVM---SVSALQNELGQADVVIKPQVLDLGAVGGFDQKKRAIRL 276 Query: 315 GWEAAQ 320 G EAA+ Sbjct: 277 GEEAAR 282 >NMA0225 [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily NmA Neisseria meningitidis Z2491 Length = 300 Score = 126 bits (317), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 94/300 (31%), Positives = 148/300 (49%), Gaps = 48/300 (16%) Query: 27 AENSSTAAPAAT-QPRPRVCLVLSGGGARGYAHLGVLQYLEQLHIPIDCIAGTSMGALIG 85 A N++ P T +P V L L GG ++G+AH+G+++ L++ IP+ + GTS G+++G Sbjct: 28 AGNNAARKPVQTAKPAAVVGLALGGGASKGFAHVGIIKVLKENGIPVKVVTGTSAGSIVG 87 Query: 86 GLYASGLDAGELERR---LAATNLSDIAFDRNERSRLPQAQREDEFQYPISISAGLDGSK 142 L+ASG+ LE L T+L D+ Sbjct: 88 SLFASGMSPDRLELEAEILGKTDLVDLTLS------------------------------ 117 Query: 143 LKLASGLVQGNKLLALLQNWTAQLPANIDFARLPIPFRAVATDLSLGSEVVLDHGSLPRA 202 SG ++G KL QN+ + + PI F AVATD G V + G+ +A Sbjct: 118 ---TSGFIKGEKL----QNYINRKVGGRRIQQFPIKFAAVATDFETGKAVAFNQGNAGQA 170 Query: 203 MRASMAVPGLFAPFRIDQRTLVDGGLVSNLPVQTARDMGADVVIAVNI-ATPLQDAAQLQ 261 +RAS A+P +F P I + T VDGGL +PV AR GA+ VIAV+I A P ++ + Q Sbjct: 171 VRASAAIPNVFQPVIIGRHTYVDGGLSQPVPVSAARRQGANFVIAVDISARPSKNIS--Q 228 Query: 262 SPTAVAQQMVGILIQQNVKAQKALLGAQDILIEPQMEGM-SFTDFARGKDGVNAGWEAAQ 320 + Q + ++ +V A + LG D++I+PQ+ + + F + K + G EAA+ Sbjct: 229 GFFSYLDQTLNVM---SVSALQNELGQADVVIKPQVLDLGAVGGFDQKKRAIRLGEEAAR 285 >TP1033 Non COG Length = 311 Score = 123 bits (308), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 85/215 (39%), Positives = 107/215 (49%), Gaps = 18/215 (8%) Query: 46 LVLSGGGARGYAHLGVLQYLEQLHIPI-DCIAGTSMGALIGGLYASGLDAGELERRLAAT 104 LVLSGGGARG AH+GVL+ LE L +P C+ G SMGA++G LYA G+ E+E A Sbjct: 5 LVLSGGGARGIAHIGVLKALEALQVPPPQCVVGCSMGAVVGALYALGMSVREME----AF 60 Query: 105 NLSDIAFDRNERSRLPQAQREDEFQYPIS---------ISAGLDGSKLKLASGLVQGNKL 155 D +R P A E + + G+ + L GL G K Sbjct: 61 FQRDFVISDYVNARDPSACVEAGMVWGARAAFQRLGKLVQLGVSLNTLVRGLGLDSGEKF 120 Query: 156 LALLQNWTAQLPANIDFARLPIPFRAVATDLSLGSEVVLDHGSLPRAMRASMAVPGLFAP 215 LL T F IPF A +L G+EVVL G L RA+RAS A PG+FAP Sbjct: 121 ATLLTRVTG----GKSFHDCKIPFLCNAVNLCTGAEVVLSSGVLARALRASCAYPGVFAP 176 Query: 216 FRIDQRTLVDGGLVSNLPVQTARDMGADVVIAVNI 250 R + L DG +++N PV AR G D V+AV Sbjct: 177 VRQEGVYLADGCILNNTPVWIARAQGFDAVLAVTF 211 >PA3339_2 [M] COG0729 Outer membrane protein Pae Pseudomonas aeruginosa Length = 420 Score = 122 bits (306), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 115/410 (28%), Positives = 186/410 (45%), Gaps = 23/410 (5%) Query: 356 IDAIEIRSGSRIPASYVRSRLAVKEGDVYDGQRINQQLSQLSTNGDFNNVTQELVSREDG 415 IDAI + + S++ +R + G D R+ +S L F+ V Q V +E Sbjct: 27 IDAIRVENNSKVSDEVIRHYIRQPLGTRLDLGRLQDDMSTLYGLDYFDQV-QYRVVKEKK 85 Query: 416 RHVLLIDAEEKSWGPQYLLFGLGVSNSFNGRGGFNLQLGHRYPWMNQSGLEWRNDLVLGA 475 + L+I A K G +L GL +S+ G FNL +R +N+ G EW + LG Sbjct: 86 LNTLVIHATGKKGGTDFLRLGLNLSDDMRGESTFNLGGSYRMNGLNRLGAEWLTRVQLG- 144 Query: 476 KRASLQTELRQPIWGSTGAYLSPYLEVSRRYVDLYPDGSDVKASPINEYRIDSAQGGLDL 535 R L +E QP+ + +++P+L + VD+ D P+ YR++ GL++ Sbjct: 145 DRQELYSEFYQPLDVGSRYFVAPFLFHEAQNVDVTEDN-----DPLLRYRLERYGYGLNV 199 Query: 536 GLPLSRLGELRLGLSYQHVNYSPTYNLAAGGGLLFESVQTSQPVARLRLTIDQLDDALFP 595 G ++ GE+RLG V ++ G L + ++ L+ + D +DD FP Sbjct: 200 GRQIANNGEIRLG----AVQAYGKADVRIGDPSL-PDIDFTEGYYELKYSFDTVDDVNFP 254 Query: 596 RKGYYLSAEANR---GLGSDEHRFSNVQARTLWAVSRERNTLNVALEGASSLSANSAGI- 651 +G + R LGSD+ + R A+S +T G + + A + Sbjct: 255 HEGEEIGLTMRRYDKSLGSDDS-YRQWDLRLNKALSFGADTW--VFGGGYGRTLDDAEVV 311 Query: 652 --GFTLGGFQHLSAYAPDQFFGNYLLYGRLSWLRDLVDTSLPGLRNPV-LGASLEAGNVW 708 FTLGG + LS + D G GR+ + R L + S L P+ LG S+E G +W Sbjct: 312 TSSFTLGGARELSGFRRDALSGQNYSLGRIVYYRRLTERSFLPLDFPLYLGGSIERGRIW 371 Query: 709 QSRDAFGDGPYKKSLSLFLGGSSPVGPLYFGVALGQQGVWNLYLQLGRVF 758 + + + D Y + SL +G +P+GPL F + + YL LG+ F Sbjct: 372 NNDNEY-DSGYINAASLMIGFDTPLGPLTFSYGINDENFKAFYLNLGQNF 420