BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0038.p (206 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1746 [D] COG2917 Intracellular septation protein A Rso Ralsto... 218 6e-57 YPO2196 [D] COG2917 Intracellular septation protein A Ype Yersin... 142 7e-34 yciB [D] COG2917 Intracellular septation protein A Eco Escherich... 141 1e-33 ZyciB [D] COG2917 Intracellular septation protein A EcZ Escheric... 141 1e-33 ECs1754 [D] COG2917 Intracellular septation protein A Ecs Escher... 141 1e-33 PA3201 [D] COG2917 Intracellular septation protein A Pae Pseudom... 134 1e-31 STM1735 [D] COG2917 Intracellular septation protein A Sty Salmon... 132 7e-31 NMB0342 [D] COG2917 Intracellular septation protein A Nme Neisse... 124 1e-28 NMA2145 [D] COG2917 Intracellular septation protein A NmA Neisse... 124 1e-28 VC1700 [D] COG2917 Intracellular septation protein A Vch Vibrio ... 121 8e-28 >RSc1746 [D] COG2917 Intracellular septation protein A Rso Ralstonia solanacearum Length = 186 Score = 218 bits (556), Expect = 6e-57, Method: Compositional matrix adjust. Identities = 112/205 (54%), Positives = 143/205 (69%), Gaps = 29/205 (14%) Query: 1 MKFLFDLFPVILFFGVFKWAEGHPSAAQDLVMQYLGGAMSAGTVTAAQAPILLSTAVAIV 60 MKFLFDLFPVILFF FK A I ++T VA+V Sbjct: 1 MKFLFDLFPVILFFAAFK-----------------------------VAGIYVATTVAMV 31 Query: 61 ASLGQIAWLLLRRRKVDAMLWVSLAIIVVFGGATIYFRDDTFIKWKPTILYWAFGLALLV 120 A++ QIAW+ + RKVDAM W+SL IIVVFGGAT+ F +DTFIKWKPT+LYW FG+ LL Sbjct: 32 ATVAQIAWVWFKHRKVDAMQWLSLLIIVVFGGATLIFHNDTFIKWKPTVLYWMFGVVLLG 91 Query: 121 SQLFMKKNLIRVMMEKQVSLPEPVWPRLNLAWIVFFAVMGVLNLYIAFNYPLDTWVNFKM 180 S + ++KNLIR MME+QVSLPEP+W RLNL W +FF MG LNLY+A+++ D WVNFK+ Sbjct: 92 SAVLLRKNLIRAMMEQQVSLPEPMWGRLNLVWSLFFLAMGGLNLYVAYHFDTDVWVNFKL 151 Query: 181 FGSMGLMFAFIIGQSLFLSKYMKDE 205 FGSMGLM FI+ QS++L+++M++ Sbjct: 152 FGSMGLMVVFILVQSVWLARHMQER 176 >YPO2196 [D] COG2917 Intracellular septation protein A Ype Yersinia pestis Length = 180 Score = 142 bits (357), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 73/156 (46%), Positives = 106/156 (67%) Query: 51 ILLSTAVAIVASLGQIAWLLLRRRKVDAMLWVSLAIIVVFGGATIYFRDDTFIKWKPTIL 110 I +++ IVA+L +A+ L+ RKV+ M V+ A+++VFG T+ F D FIKWK T+L Sbjct: 22 IFVASGALIVATLVALAFTWLKYRKVEKMTLVTAAMVLVFGTLTLAFHSDLFIKWKVTVL 81 Query: 111 YWAFGLALLVSQLFMKKNLIRVMMEKQVSLPEPVWPRLNLAWIVFFAVMGVLNLYIAFNY 170 Y F LALLVSQ MKK LI+ M+ K+++LP+ VW LNL+W +FF V G+LN+Y+AF Sbjct: 82 YVLFALALLVSQWVMKKPLIQRMLGKELTLPDKVWSTLNLSWAIFFLVCGLLNIYVAFWL 141 Query: 171 PLDTWVNFKMFGSMGLMFAFIIGQSLFLSKYMKDEQ 206 P D WVNFK+FG L F + +++ ++M +EQ Sbjct: 142 PQDIWVNFKVFGLTALTLIFTLISGVYIYRHMPEEQ 177 >yciB [D] COG2917 Intracellular septation protein A Eco Escherichia coli K12 Length = 179 Score = 141 bits (355), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 79/206 (38%), Positives = 121/206 (58%), Gaps = 29/206 (14%) Query: 1 MKFLFDLFPVILFFGVFKWAEGHPSAAQDLVMQYLGGAMSAGTVTAAQAPILLSTAVAIV 60 MK D P+++FF +K + + AA A ++++TA+ ++ Sbjct: 1 MKQFLDFLPLVVFFAFYKIYD----------------------IYAATAALIVATAIVLI 38 Query: 61 ASLGQIAWLLLRRRKVDAMLWVSLAIIVVFGGATIYFRDDTFIKWKPTILYWAFGLALLV 120 S W+ R RKV+ M ++ ++VVFGG T++F +D FIKWK T++Y F ALLV Sbjct: 39 YS-----WV--RFRKVEKMALITFVLVVVFGGLTLFFHNDEFIKWKVTVIYALFAGALLV 91 Query: 121 SQLFMKKNLIRVMMEKQVSLPEPVWPRLNLAWIVFFAVMGVLNLYIAFNYPLDTWVNFKM 180 SQ MKK LI+ M+ K+++LP+PVW +LNLAW VFF + G+ N+YIAF P + WVNFK+ Sbjct: 92 SQWVMKKPLIQRMLGKELTLPQPVWSKLNLAWAVFFILCGLANIYIAFWLPQNIWVNFKV 151 Query: 181 FGSMGLMFAFIIGQSLFLSKYMKDEQ 206 FG L F + +++ ++M E Sbjct: 152 FGLTALTLIFTLLSGIYIYRHMPQED 177 >ZyciB [D] COG2917 Intracellular septation protein A EcZ Escherichia coli O157:H7 EDL933 Length = 179 Score = 141 bits (355), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 79/206 (38%), Positives = 121/206 (58%), Gaps = 29/206 (14%) Query: 1 MKFLFDLFPVILFFGVFKWAEGHPSAAQDLVMQYLGGAMSAGTVTAAQAPILLSTAVAIV 60 MK D P+++FF +K + + AA A ++++TA+ ++ Sbjct: 1 MKQFLDFLPLVVFFAFYKIYD----------------------IYAATAALIVATAIVLI 38 Query: 61 ASLGQIAWLLLRRRKVDAMLWVSLAIIVVFGGATIYFRDDTFIKWKPTILYWAFGLALLV 120 S W+ R RKV+ M ++ ++VVFGG T++F +D FIKWK T++Y F ALLV Sbjct: 39 YS-----WV--RFRKVEKMALITFVLVVVFGGLTLFFHNDEFIKWKVTVIYALFAGALLV 91 Query: 121 SQLFMKKNLIRVMMEKQVSLPEPVWPRLNLAWIVFFAVMGVLNLYIAFNYPLDTWVNFKM 180 SQ MKK LI+ M+ K+++LP+PVW +LNLAW VFF + G+ N+YIAF P + WVNFK+ Sbjct: 92 SQWVMKKPLIQRMLGKELTLPQPVWSKLNLAWAVFFILCGLANIYIAFWLPQNIWVNFKV 151 Query: 181 FGSMGLMFAFIIGQSLFLSKYMKDEQ 206 FG L F + +++ ++M E Sbjct: 152 FGLTALTLIFTLLSGIYIYRHMPQED 177 >ECs1754 [D] COG2917 Intracellular septation protein A Ecs Escherichia coli O157:H7 Length = 179 Score = 141 bits (355), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 79/206 (38%), Positives = 121/206 (58%), Gaps = 29/206 (14%) Query: 1 MKFLFDLFPVILFFGVFKWAEGHPSAAQDLVMQYLGGAMSAGTVTAAQAPILLSTAVAIV 60 MK D P+++FF +K + + AA A ++++TA+ ++ Sbjct: 1 MKQFLDFLPLVVFFAFYKIYD----------------------IYAATAALIVATAIVLI 38 Query: 61 ASLGQIAWLLLRRRKVDAMLWVSLAIIVVFGGATIYFRDDTFIKWKPTILYWAFGLALLV 120 S W+ R RKV+ M ++ ++VVFGG T++F +D FIKWK T++Y F ALLV Sbjct: 39 YS-----WV--RFRKVEKMALITFVLVVVFGGLTLFFHNDEFIKWKVTVIYALFAGALLV 91 Query: 121 SQLFMKKNLIRVMMEKQVSLPEPVWPRLNLAWIVFFAVMGVLNLYIAFNYPLDTWVNFKM 180 SQ MKK LI+ M+ K+++LP+PVW +LNLAW VFF + G+ N+YIAF P + WVNFK+ Sbjct: 92 SQWVMKKPLIQRMLGKELTLPQPVWSKLNLAWAVFFILCGLANIYIAFWLPQNIWVNFKV 151 Query: 181 FGSMGLMFAFIIGQSLFLSKYMKDEQ 206 FG L F + +++ ++M E Sbjct: 152 FGLTALTLIFTLLSGIYIYRHMPQED 177 >PA3201 [D] COG2917 Intracellular septation protein A Pae Pseudomonas aeruginosa Length = 195 Score = 134 bits (337), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 77/204 (37%), Positives = 116/204 (56%), Gaps = 18/204 (8%) Query: 1 MKFLFDLFPVILFFGVFKWAEGHPSAAQDLVMQYLGGAMSAGTVTAAQAPILLSTAVAIV 60 MK D P+ILFF V+K + +++ G +S I +TA I+ Sbjct: 1 MKQFIDFIPLILFFIVYKIDPQN--------VEFAGFNLSG---------IYGATATLIL 43 Query: 61 ASLGQIAWLLLRRRKVDAMLWVSLAIIVVFGGATIYFRDDTFIKWKPTILYWAFGLALLV 120 AS+ L L+ R ++ W +L +V GG T+ F +DTF+KWK ++ W F LA Sbjct: 44 ASVIVYGALWLKHRHLEKSQWFTLGACLVLGGLTLAFHEDTFLKWKAPLVNWLFALAFAG 103 Query: 121 SQLFMKKNLIRVMMEKQVSLPEPVWPRLNLAWIVFFAVMGVLNLYIAFNYPLDTWVNFKM 180 S K +I+ +M + LP+ +W RLN+AW+VFF V G NLY+ F YP + WV+FK+ Sbjct: 104 SHFIGDKPMIQRIMGHAIQLPQGLWVRLNIAWVVFFLVCGFANLYVVFTYP-NFWVDFKV 162 Query: 181 FGSMGLMFAFIIGQSLFLSKYMKD 204 FGS+G+ F+IGQ LFL++++ D Sbjct: 163 FGSLGMTLLFLIGQGLFLARHLHD 186 >STM1735 [D] COG2917 Intracellular septation protein A Sty Salmonella typhimurium LT2 Length = 179 Score = 132 bits (331), Expect = 7e-31, Method: Compositional matrix adjust. Identities = 72/206 (34%), Positives = 118/206 (57%), Gaps = 29/206 (14%) Query: 1 MKFLFDLFPVILFFGVFKWAEGHPSAAQDLVMQYLGGAMSAGTVTAAQAPILLSTAVAIV 60 MK D P+++FF +K + + AA + ++++TA+ ++ Sbjct: 1 MKQFLDFLPLVVFFAFYKLYD----------------------IYAATSALIVATAIVLI 38 Query: 61 ASLGQIAWLLLRRRKVDAMLWVSLAIIVVFGGATIYFRDDTFIKWKPTILYWAFGLALLV 120 S W+ R RK++ M ++ ++ VFGG T++F +D FIKWK T++Y F ALL+ Sbjct: 39 YS-----WV--RYRKIEKMALITFVLVAVFGGLTLFFHNDEFIKWKVTVIYALFAGALLI 91 Query: 121 SQLFMKKNLIRVMMEKQVSLPEPVWPRLNLAWIVFFAVMGVLNLYIAFNYPLDTWVNFKM 180 SQ MKK LI+ M+ K+++LP+ VW +LNLAW +FF G+ N+YIAF P + WVNFK+ Sbjct: 92 SQWVMKKPLIQRMLGKELALPQQVWSKLNLAWALFFIACGLANIYIAFWLPQNIWVNFKV 151 Query: 181 FGSMGLMFAFIIGQSLFLSKYMKDEQ 206 FG L F + +++ +++ E Sbjct: 152 FGLTALTLIFTLLSGVYIYRHLPQED 177 >NMB0342 [D] COG2917 Intracellular septation protein A Nme Neisseria meningitidis MC58 Length = 176 Score = 124 bits (312), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 79/206 (38%), Positives = 110/206 (53%), Gaps = 30/206 (14%) Query: 1 MKFLFDLFPVILFFGVFKWAEGHPSAAQDLVMQYLGGAMSAGTVTAAQAPILLSTAVAIV 60 MKF+ DL VILFF + TVT ++ +TAVA+V Sbjct: 1 MKFVSDLLSVILFFATY-------------------------TVTK---NMIAATAVALV 32 Query: 61 ASLGQIAWLLLRRRKVDAMLWVSLAIIVVFGGATIYFRDDTFIKWKPTILYWAFGLALLV 120 A + Q A+L + +K+D M WV L +IVVFGGATI D FI WKP++L+W L L Sbjct: 33 AGVVQAAFLYWKYKKLDTMQWVGLVLIVVFGGATIVLGDSRFIMWKPSVLFWLGALFLWG 92 Query: 121 SQLFMKKNLIRVMMEKQVSLPEPVWPRLNLAWIVFFAVMGVLNLYIAFNYPLDTWVNFKM 180 S L KN ++ + +++ LP+ VW +L W+ F MG+ N ++ F WVN+KM Sbjct: 93 SHL-AGKNGLKASIGREIQLPDAVWAKLTYMWVGFLIFMGIANWFV-FTRFESQWVNYKM 150 Query: 181 FGSMGLMFAFIIGQSLFLSKYMKDEQ 206 FGS LM F I Q ++LS +K E Sbjct: 151 FGSTALMLVFFIIQGIYLSTCLKKED 176 >NMA2145 [D] COG2917 Intracellular septation protein A NmA Neisseria meningitidis Z2491 Length = 176 Score = 124 bits (312), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 79/206 (38%), Positives = 110/206 (53%), Gaps = 30/206 (14%) Query: 1 MKFLFDLFPVILFFGVFKWAEGHPSAAQDLVMQYLGGAMSAGTVTAAQAPILLSTAVAIV 60 MKF+ DL VILFF + TVT ++ +TAVA+V Sbjct: 1 MKFVSDLLSVILFFATY-------------------------TVTK---NMIAATAVALV 32 Query: 61 ASLGQIAWLLLRRRKVDAMLWVSLAIIVVFGGATIYFRDDTFIKWKPTILYWAFGLALLV 120 A + Q A+L + +K+D M WV L +IVVFGGATI D FI WKP++L+W L L Sbjct: 33 AGVVQAAFLYWKYKKLDTMQWVGLVLIVVFGGATIVLGDSRFIMWKPSVLFWLGALFLWG 92 Query: 121 SQLFMKKNLIRVMMEKQVSLPEPVWPRLNLAWIVFFAVMGVLNLYIAFNYPLDTWVNFKM 180 S L KN ++ + +++ LP+ VW +L W+ F MG+ N ++ F WVN+KM Sbjct: 93 SHL-AGKNGLKASIGREIQLPDAVWAKLTYMWVGFLIFMGIANWFV-FTRFESQWVNYKM 150 Query: 181 FGSMGLMFAFIIGQSLFLSKYMKDEQ 206 FGS LM F I Q ++LS +K E Sbjct: 151 FGSTALMLVFFIIQGIYLSTCLKKED 176 >VC1700 [D] COG2917 Intracellular septation protein A Vch Vibrio cholerae Length = 181 Score = 121 bits (304), Expect = 8e-28, Method: Compositional matrix adjust. Identities = 68/205 (33%), Positives = 109/205 (53%), Gaps = 30/205 (14%) Query: 1 MKFLFDLFPVILFFGVFKWAEGHPSAAQDLVMQYLGGAMSAGTVTAAQAPILLSTAVAIV 60 MK L D P+I+FF ++K+ + I ++T I Sbjct: 1 MKQLLDFIPLIIFFALYKFYD-----------------------------IYVATGALIA 31 Query: 61 ASLGQIAWLLLRRRKVDAMLWVSLAIIVVFGGATIYFRDDTFIKWKPTILYWAFGLALLV 120 A+ Q+ +KV+ M ++ ++ +FGG T+ DD FIKWK TI+Y F L L + Sbjct: 32 ATTVQVIVTYAMYKKVEKMQLITFVMVALFGGMTLALHDDNFIKWKVTIVYVVFALGLTI 91 Query: 121 SQLFMKKNLIRVMMEKQVSLPEPVWPRLNLAWIVFFAVMGVLNLYIAFNYPLDTWVNFKM 180 SQ+ M K I+ M+ K+++LP+ VW +N AW++FF+ LNLY+A++ PLD WVNFK+ Sbjct: 92 SQI-MGKPAIKGMLGKELTLPDAVWSTINWAWVMFFSGCAALNLYVAYHLPLDVWVNFKV 150 Query: 181 FGSMGLMFAFIIGQSLFLSKYMKDE 205 FG + F + ++ K++ E Sbjct: 151 FGLLAATLVFTLLTGGYIYKHLPHE 175