BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0008.p (242 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA0355 [R] COG0693 Putative intracellular protease/amidase Pae P... 216 4e-56 DR1199 [R] COG0693 Putative intracellular protease/amidase Dra D... 158 9e-39 lin2358 [R] COG0693 Putative intracellular protease/amidase Lin ... 133 3e-31 PA4171 [R] COG0693 Putative intracellular protease/amidase Pae P... 130 2e-30 PH1704 [R] COG0693 Putative intracellular protease/amidase Pho P... 130 3e-30 AGl1423 [R] COG0693 Putative intracellular protease/amidase Atu ... 127 2e-29 PAB0311 [R] COG0693 Putative intracellular protease/amidase Pab ... 125 1e-28 MA2531 [R] COG0693 Putative intracellular protease/amidase Mac M... 119 8e-27 STM3269 [R] COG0693 Putative intracellular protease/amidase Sty ... 119 8e-27 APE0319 [R] COG0693 Putative intracellular protease/amidase Ape ... 118 2e-26 >PA0355 [R] COG0693 Putative intracellular protease/amidase Pae Pseudomonas aeruginosa Length = 179 Score = 216 bits (550), Expect = 4e-56, Method: Compositional matrix adjust. Identities = 105/177 (59%), Positives = 125/177 (70%) Query: 1 MSNRYHQLKVAVLVTDGFEQAELLEPKKALEAAGATVHILSDKSDSVQGFKHVDKGEVVS 60 M+ H VA LVTDGFEQ EL PKKALE AGATV ILSDK+ V+G+ H E Sbjct: 1 MTQSLHGKVVAALVTDGFEQVELTGPKKALEDAGATVRILSDKAGEVRGWNHHQPAEAFR 60 Query: 61 VDGSLDNASADDYSAVLLPGGVVNGDAMRLLPQARNFVRAANDAEKPIASICHGGWLLIS 120 VDG+ ++AS DDY A+LLPGGV+N D +R L +A+ A A KP+A ICHG WLLIS Sbjct: 61 VDGTFEDASLDDYDALLLPGGVINSDQIRSLAKAQELAIRAEQASKPVAVICHGAWLLIS 120 Query: 121 AGIAKGRTVTSWPSLQDDFKNAGSQWVDQEVVRDENFVSSRKPADIPAFNNEFMKLL 177 AG+ +GRT+TSWPSL+DD NAG WVDQEV D VSSRKP DIPAFN F+++L Sbjct: 121 AGLVQGRTLTSWPSLKDDINNAGGHWVDQEVAVDGKLVSSRKPEDIPAFNRRFIEIL 177 >DR1199 [R] COG0693 Putative intracellular protease/amidase Dra Deinococcus radiodurans Length = 190 Score = 158 bits (400), Expect = 9e-39, Method: Compositional matrix adjust. Identities = 80/180 (44%), Positives = 108/180 (60%), Gaps = 1/180 (0%) Query: 9 KVAVLVTDGFEQAELLEPKKALEAAGATVHILSDKSDSVQGFK-HVDKGEVVSVDGSLDN 67 K+A+L DG E+ EL P+ A+EAAG T ++S + +Q K ++ E VD + Sbjct: 11 KIAILAADGVEEIELTSPRAAIEAAGGTTELISLEPGEIQSMKGDIEPQEKYRVDHVVSE 70 Query: 68 ASADDYSAVLLPGGVVNGDAMRLLPQARNFVRAANDAEKPIASICHGGWLLISAGIAKGR 127 DY +LLPGG VN D +RL A FVR DA KPIA+ICHG W L GIA+G Sbjct: 71 VQVSDYDGLLLPGGTVNPDKLRLEEGAMKFVRDMYDAGKPIAAICHGPWSLSETGIAQGL 130 Query: 128 TVTSWPSLQDDFKNAGSQWVDQEVVRDENFVSSRKPADIPAFNNEFMKLLDEQQRREHRQ 187 +TSWPSL+ + AG+QWVD+E V D+ V+SRKP D+PAFN + ++ E R+ Sbjct: 131 KMTSWPSLKRELTLAGAQWVDEECVTDKGVVTSRKPDDLPAFNKKIVEEFAEGDHSSRRK 190 >lin2358 [R] COG0693 Putative intracellular protease/amidase Lin Listeria innocua Length = 173 Score = 133 bits (335), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 70/171 (40%), Positives = 104/171 (60%), Gaps = 4/171 (2%) Query: 9 KVAVLVTDGFEQAELLEPKKALEAAGATVHILSDKSDSVQGFKHVDKGEVVSVDGSLDNA 68 KV LV++ FE EL P L AGA+VH++++++ V H G V+ D D+ Sbjct: 7 KVIALVSEDFEDLELWYPVLRLREAGASVHLVAEEAKKVY---HGKYGVPVTSDYDFDSV 63 Query: 69 SADDYSAVLLPGGVVNGDAMRLLPQARNFVRAANDAEKPIASICHGGWLLISAGIAKGRT 128 A+DY +L+PGG + D +R N VRA + A+KPI ICH GW+L+SAGI +G Sbjct: 64 RAEDYDGILVPGGW-SPDKLRRFDSVLNLVRAFDKAKKPIGQICHAGWVLVSAGILEGVN 122 Query: 129 VTSWPSLQDDFKNAGSQWVDQEVVRDENFVSSRKPADIPAFNNEFMKLLDE 179 VTS P ++DD NAG+ W ++ VV D + +SSR+P D+P + F+ L++ Sbjct: 123 VTSTPGIKDDMTNAGAIWHNEPVVTDGHIISSRRPPDLPEYLPAFISALED 173 >PA4171 [R] COG0693 Putative intracellular protease/amidase Pae Pseudomonas aeruginosa Length = 187 Score = 130 bits (328), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 72/176 (40%), Positives = 103/176 (58%), Gaps = 6/176 (3%) Query: 1 MSNRYHQLKVAVLVTD-GFEQAELLEPKKALEAAGATVHILSDKSDSVQGFKH-VDKGEV 58 MS + V V+ + G E+ ELLEP K L+ GATV + + Q + H +K + Sbjct: 1 MSAKLQGKNVLVITANTGIERDELLEPLKTLKQQGATVTHATIEGGEAQTWVHDSEKDLI 60 Query: 59 VSVDGSLDNASADDYSAVLLPGGVVNGDAMRLLPQARNFVRAANDAEKPIASICHGGWLL 118 V+ D L A+DY +L+PGG VN D +R +AR VR ++A K +A+ICHG WLL Sbjct: 61 VNSDARLQGLRAEDYDLLLVPGGTVNADTLRQDSEARRLVREFSEAGKTVAAICHGPWLL 120 Query: 119 ISAGIAKGRTVTSWPSLQDDFKNAGSQWVDQEV----VRDENFVSSRKPADIPAFN 170 I AG+A+G+T+TS+ S++ D NAG+ WVD V ++SR P D+ AFN Sbjct: 121 IDAGVARGKTLTSYSSVRIDLTNAGADWVDTRVKVCPANGWTLITSRNPGDLQAFN 176 >PH1704 [R] COG0693 Putative intracellular protease/amidase Pho Pyrococcus horikoshii Length = 166 Score = 130 bits (326), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 74/170 (43%), Positives = 105/170 (61%), Gaps = 5/170 (2%) Query: 8 LKVAVLVTDGFEQAELLEPKKALEAAGATVHILSDKSDSVQGFKHVDKGEVVSVDGSLDN 67 +KV L + FE EL+ P L+ G V+I S + ++ G KH G V VD + D Sbjct: 1 MKVLFLTANEFEDVELIYPYHRLKEEGHEVYIASFERGTITG-KH---GYSVKVDLTFDK 56 Query: 68 ASADDYSAVLLPGGVVNGDAMRLLPQARNFVRAANDAEKPIASICHGGWLLISAGIAKGR 127 + +++ A++LPGG + +RL +A + R KP+ASICHG +LISAG+ +GR Sbjct: 57 VNPEEFDALVLPGGRAP-ERVRLNEKAVSIARKMFSEGKPVASICHGPQILISAGVLRGR 115 Query: 128 TVTSWPSLQDDFKNAGSQWVDQEVVRDENFVSSRKPADIPAFNNEFMKLL 177 TS+P ++DD NAG +WVD EVV D N+VSSR PAD+ A+ EF+KLL Sbjct: 116 KGTSYPGIKDDMINAGVEWVDAEVVVDGNWVSSRVPADLYAWMREFVKLL 165 >AGl1423 [R] COG0693 Putative intracellular protease/amidase Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 186 Score = 127 bits (320), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 68/178 (38%), Positives = 107/178 (60%), Gaps = 1/178 (0%) Query: 9 KVAVLVTDGFEQAELLEPKKALEAAGATVHILSDKSDSVQGFKHVDKGEVVSVDGSLDNA 68 K+ +L TDG+E++EL P + L+A GA V I S K ++ + + G+ ++VD S Sbjct: 8 KILILATDGYERSELRVPYEQLKARGADVKIASIKEGEIKSWDEKNWGDSIAVDLSAKTV 67 Query: 69 SADDYSAVLLPGGVVNGDAMRLLPQARNFVRAANDAEKPIASICHGGWLLISAGIAKGRT 128 +D+ A++LPGG +N D +R A VR + K +A+ICH WLLI A +GR Sbjct: 68 KVNDFDALVLPGGQINPDILRHDEDAMRVVRDFVKSGKVVAAICHAPWLLIEADALRGRD 127 Query: 129 VTSWPSLQDDFKNAGSQWVDQEVVRDENFVSSRKPADIPAFNNEFMKLLDEQQRREHR 186 TS+ S++ D KNAG+ W D++VV D+ ++SR P D+ AF + ++ + E+ R E R Sbjct: 128 ATSYWSIKTDLKNAGANWKDEKVVTDKGIITSRSPDDLDAFVAKIVEEV-EEGRHERR 184 >PAB0311 [R] COG0693 Putative intracellular protease/amidase Pab Pyrococcus abyssi Length = 166 Score = 125 bits (313), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 72/170 (42%), Positives = 102/170 (60%), Gaps = 5/170 (2%) Query: 8 LKVAVLVTDGFEQAELLEPKKALEAAGATVHILSDKSDSVQGFKHVDKGEVVSVDGSLDN 67 ++V +L D FE EL+ P L+ G V + S K + G KH G V+VD + + Sbjct: 1 MRVLILSADQFEDVELIYPYHRLKEEGHEVLVASFKRGVITG-KH---GYTVNVDLAFEE 56 Query: 68 ASADDYSAVLLPGGVVNGDAMRLLPQARNFVRAANDAEKPIASICHGGWLLISAGIAKGR 127 + D++ A++LPGG + +RL +A + KP+ASICHG +LISAG+ +GR Sbjct: 57 VNPDEFDALVLPGGRAP-ERVRLNEKAVEIAKKMFSEGKPVASICHGPQILISAGVLRGR 115 Query: 128 TVTSWPSLQDDFKNAGSQWVDQEVVRDENFVSSRKPADIPAFNNEFMKLL 177 TS+P ++DD NAG WVD EVV D N+VSSR P D+ A+ EF+KLL Sbjct: 116 RGTSYPGIKDDMINAGVDWVDAEVVVDGNWVSSRVPGDLYAWMREFVKLL 165 >MA2531 [R] COG0693 Putative intracellular protease/amidase Mac Methanosarcina acetivorans str.C2A Length = 166 Score = 119 bits (297), Expect = 8e-27, Method: Compositional matrix adjust. Identities = 68/170 (40%), Positives = 93/170 (54%), Gaps = 5/170 (2%) Query: 8 LKVAVLVTDGFEQAELLEPKKALEAAGATVHILSDKSDSVQGFKHVDKGEVVSVDGSLDN 67 +K V DGFE EL P L+ G T H+ S K + G KH G ++ D + + Sbjct: 1 MKALVFGADGFEDLELFYPYHRLKEEGITTHVASMKKGPITG-KH---GYEITADIAFKD 56 Query: 68 ASADDYSAVLLPGGVVNGDAMRLLPQARNFVRAANDAEKPIASICHGGWLLISAGIAKGR 127 ++ DY +++ GG + MRL A V+ KP+ASICHG +L+SA + KGR Sbjct: 57 VNSADYDIIVISGGK-GPEKMRLDKDALEIVKNFFKKNKPVASICHGPQVLVSADVIKGR 115 Query: 128 TVTSWPSLQDDFKNAGSQWVDQEVVRDENFVSSRKPADIPAFNNEFMKLL 177 T W ++DD AG+Q+ D EVV D N VSSR P D+ AF E +KLL Sbjct: 116 KATCWIGIRDDIIAAGAQYEDSEVVVDGNLVSSRNPGDLHAFGREMIKLL 165 >STM3269 [R] COG0693 Putative intracellular protease/amidase Sty Salmonella typhimurium LT2 Length = 172 Score = 119 bits (297), Expect = 8e-27, Method: Compositional matrix adjust. Identities = 71/176 (40%), Positives = 107/176 (60%), Gaps = 16/176 (9%) Query: 9 KVAVLVTDGFEQAELLEPKKALEAAG-ATVHILSDKSDSVQGFKHVDKGEV-VSVDGSLD 66 K+AVL+TD FE +E P AG + I + +V+G KGE V++D ++D Sbjct: 4 KIAVLITDEFEDSEFTSPAAEFRQAGHEVITIEKEAGKTVKG----KKGEASVTIDKAID 59 Query: 67 NASADDYSAVLLPGG----VVNGDAMRLLPQARNFVRAANDAEKPIASICHGGWLLISAG 122 + D++ A+LLPGG + GD+ R + R+FV + KP+ +ICHG LLISA Sbjct: 60 DVRPDEFDALLLPGGHSPDYLRGDS-RFVDFTRDFVNSG----KPVFAICHGPQLLISAD 114 Query: 123 IAKGRTVTSWPSLQDDFKNAGSQWVDQEVVRDEN-FVSSRKPADIPAFNNEFMKLL 177 + +GR +T+ + D KNAG+++ DQEVV D++ V+SR P D+PAFN E ++LL Sbjct: 115 VIRGRKLTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLPAFNREALRLL 170 >APE0319 [R] COG0693 Putative intracellular protease/amidase Ape Aeropyrum pernix Length = 180 Score = 118 bits (295), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 65/170 (38%), Positives = 94/170 (55%), Gaps = 5/170 (2%) Query: 9 KVAVLVTDGFEQAELLEPKKALEAAGATVHILSDKSDSVQGFKHVDKGEVVSVDGSLDNA 68 + ++ DGFE ELL P L AG + + ++G G V S + Sbjct: 3 RALIISADGFEDVELLYPYYRLVEAGFETLVAAPSRGEIKG----KMGYKVEAKLSFEEV 58 Query: 69 SADDYSAVLLPGGVVNGDAMRLLPQARNFVRAANDAEKPIASICHGGWLLISAGIAKGRT 128 +++ +++PGG + +RL A N VR + KP+A+ICHG +LISAG+ KGR Sbjct: 59 KPEEFDVLVIPGGRAP-ERVRLHEAALNIVRHFFEKNKPVATICHGPQVLISAGVVKGRR 117 Query: 129 VTSWPSLQDDFKNAGSQWVDQEVVRDENFVSSRKPADIPAFNNEFMKLLD 178 +TS+ ++DD AG WVD+ VV D N VSSR P DIP + EFM+LL+ Sbjct: 118 LTSYWGVKDDVIAAGGNWVDEPVVVDGNLVSSRYPPDIPYWMREFMRLLE 167