BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0003.p (349 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2150 [S] COG1273 Uncharacterized conserved protein Pae Pseudom... 258 1e-68 BS_ykoV [S] COG1273 Uncharacterized conserved protein Bsu Bacill... 173 5e-43 AF1726 [S] COG1273 Uncharacterized conserved protein Afu Archaeo... 168 2e-41 BH2208 [S] COG1273 Uncharacterized conserved protein Bha Bacillu... 168 2e-41 Rv0937c [S] COG1273 Uncharacterized conserved protein Mtu Mycoba... 143 7e-34 MT0964 [S] COG1273 Uncharacterized conserved protein MtC Mycobac... 143 7e-34 SMb20686 [S] COG1273 Uncharacterized conserved protein Sme Sinor... 132 1e-30 mll2074 Non COG 129 7e-30 SMb21407 [S] COG1273 Uncharacterized conserved protein Sme Sinor... 117 4e-26 AGpA66 [S] COG1273 Uncharacterized conserved protein Atu Agrobac... 115 2e-25 >PA2150 [S] COG1273 Uncharacterized conserved protein Pae Pseudomonas aeruginosa Length = 293 Score = 258 bits (659), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 132/290 (45%), Positives = 198/290 (68%), Gaps = 6/290 (2%) Query: 1 MRRALWKGAISFGLINIPVELYTAEKHDELDFTLLDQRDLSPVGYKRYNKKSGREVPWEN 60 M RA+WKGAISFGL++IPV L A +DF LDQR + PVGYKR NK +G+E+ EN Sbjct: 1 MARAIWKGAISFGLVHIPVSLSAATSSQGIDFDWLDQRSMEPVGYKRVNKVTGKEIEREN 60 Query: 61 IIKGYQYEEGKYVLMSDEDLRRANVEATQSIDIQSFVEREQVPILYYEQPYFLAPAKGGD 120 I+KG +YE+G+YV++S+E++R A+ ++TQ+I+I +FV+ +++P+ +++ PY+L P + G Sbjct: 61 IVKGVEYEKGRYVVLSEEEIRAAHPKSTQTIEIFAFVDSQEIPLQHFDTPYYLVPDRRGG 120 Query: 121 KAYALLRETLLASDKMAIAQIVIRTRQHLAALIPQGDMLQLITLRYPSELRAPDDLPVPT 180 K YALLRETL + K+A+A +V+ TRQHLA L P D L LITLR+PS++R+ D L + Sbjct: 121 KVYALLRETLERTGKVALANVVLHTRQHLALLRPLQDALVLITLRWPSQVRSLDGLELDE 180 Query: 181 RKSKKAAVTRQEVEMARALVEHMSAQWEPEQFHDTYRDDVLALIQKKIKSRQTHEVAEPD 240 + +A + ++E+EMA+ LVE M++ WEP+++ D++ D ++ L+++K Q H V Sbjct: 181 SVT-EAKLDKRELEMAKRLVEDMASHWEPDEYKDSFSDKIMKLVEEKAAKGQLHAVE--- 236 Query: 241 EAAVPASSGAKVVDLMALLKSSLEGRGKSSAKAGDDKAPQEAK--EKSGA 288 E A GA ++DL LLK SL R G +KA +AK KSGA Sbjct: 237 EEEEVAGKGADIIDLTDLLKRSLRSRAGGGKDKGSEKAGADAKGRAKSGA 286 >BS_ykoV [S] COG1273 Uncharacterized conserved protein Bsu Bacillus subtilis Length = 311 Score = 173 bits (439), Expect = 5e-43, Method: Compositional matrix adjust. Identities = 88/263 (33%), Positives = 165/263 (62%), Gaps = 12/263 (4%) Query: 4 ALWKGAISFGLINIPVELYTAEKHDELDFTLLDQRDLSPVGYKRYNKKSGREVPWENIIK 63 +WKG+ISFGL+NIP++LY A + ++ L + D +P+ Y++ + + + I+K Sbjct: 20 TMWKGSISFGLVNIPIKLYAATEDKDIKLRSLHKEDHAPIKYEKVCTNCEKTLSPDEIVK 79 Query: 64 GYQYEEGKYVLMSDEDLRRANVEATQ-SIDIQSFVEREQVPILYYEQPYFLAPAKGGDKA 122 GY+Y +GKYV+++DEDL+ E + +++I FV+ +++ +Y+ + YF+ P G KA Sbjct: 80 GYEYVKGKYVVLTDEDLKSLKQEHEEKAVEIVDFVQLQEIDPIYFNRSYFVGPGDNGTKA 139 Query: 123 YALLRETLLASDKMAIAQIVIRTRQHLAALIPQGDMLQLITLRYPSELRAPDDLP-VPTR 181 Y LLRE L ++ K+ IA + IR++Q LA L + + + ++ YP E+R+ +P VP Sbjct: 140 YTLLREALRSTGKIGIANMTIRSKQQLAILRVYENCIVMESIHYPDEVRSAAQVPGVP-- 197 Query: 182 KSKKAAVTRQEVEMARALVEHMSAQWEPEQFHDTYRDDVLALIQKKIKSRQTHEVAEPDE 241 ++ V +E++ A L++ ++A++EPE++ DTYR +L + K+++++T PD+ Sbjct: 198 --DQSNVNDKELQTAITLIDELTAKFEPEKYEDTYRQALLQRVNDKLENKET--AVTPDK 253 Query: 242 AAVPASSGAKVVDLMALLKSSLE 264 A P V+DL++ L++S++ Sbjct: 254 AP-PRED---VIDLVSALQASID 272 >AF1726 [S] COG1273 Uncharacterized conserved protein Afu Archaeoglobus fulgidus Length = 286 Score = 168 bits (426), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 91/263 (34%), Positives = 158/263 (60%), Gaps = 15/263 (5%) Query: 3 RALWKGAISFGLINIPVELYTAEKHDELDFTLLDQRDLSPVGYKRYNKKSGREVPWENII 62 RA WKG+ISFGL+NIPV++Y A E+ F LL D + Y++ +K G+EV I+ Sbjct: 35 RATWKGSISFGLVNIPVKVYKATTQKEIQFHLLHSADGGRIRYRKVCEKCGKEVSDGEIV 94 Query: 63 KGYQYEEGKYVLMSDEDLRRANVEATQSIDIQSFVEREQVPILYYEQPYFLAPAKGGDKA 122 KGY+ + +YV+++DED + +++T+SI+I+ F + ++ ++YY Y+++P KGG+KA Sbjct: 95 KGYEISKNEYVILTDEDFEKIPLKSTKSIEIRQFFDPAELGLIYYSSFYYISPDKGGEKA 154 Query: 123 YALLRETLLASDKMAIAQIVIRTRQHLAALIPQGDMLQLITLRYPSELRAPDDLPVPTRK 182 Y LL++ + ++ M I ++ +R +++L AL P + L L Y E+R+P +LP Sbjct: 155 YYLLKKAMEETNSMGIGKMTMRGKENLVALRPYDGGIVLAQLHYIDEVRSPLELP---GW 211 Query: 183 SKKAAVTRQEVEMARALVEHMSAQWEPEQFHDTYRDDVLALIQKKIKSRQTHEVAEPDEA 242 A +T +E+E+A+ L+ M + E+F D Y++ ++ LI+ K+ R+ Sbjct: 212 GAVAEITEEELELAKKLILAMKKPLKLEEFRDEYKEALMQLIEAKLSGRE---------- 261 Query: 243 AVPASSGA-KVVDLMALLKSSLE 264 + S G +V L+ LK+SLE Sbjct: 262 -IVVSEGVEEVKSLIDALKASLE 283 >BH2208 [S] COG1273 Uncharacterized conserved protein Bha Bacillus halodurans Length = 280 Score = 168 bits (425), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 87/262 (33%), Positives = 161/262 (61%), Gaps = 12/262 (4%) Query: 5 LWKGAISFGLINIPVELYTAEKHDELDFTLLDQRDLSPVGYKRYNKKSGREVPWENIIKG 64 +WKG ISFGL+NIP++L+ A ++ ++ L + +P+ Y + EV +I+K Sbjct: 6 MWKGTISFGLVNIPIKLHAATENKDVRLRQLHKECKTPINYLKVCPNCDAEVEPNDIVKA 65 Query: 65 YQYEEGKYVLMSDEDLRRANVE-ATQSIDIQSFVEREQVPILYYEQPYFLAPAKGGDKAY 123 Y+Y + K+V + +E+L E ++++I FV+ +++ +Y+++ Y+++P GG KAY Sbjct: 66 YEYAKNKFVELDEEELASLKKEQEDKAVEIIDFVKLQEIDPIYFDKSYYMSPGDGGGKAY 125 Query: 124 ALLRETLLASDKMAIAQIVIRTRQHLAALIPQGDMLQLITLRYPSELRAPDDLP-VPTRK 182 LLRE L S+K+ +A+I+IR ++HLA + + L + T+ +P E+RA D +P VP Sbjct: 126 TLLREALAESEKIGVAKIIIRAKEHLAVIRVYKNTLLMETIHFPDEVRAVDQVPNVP--- 182 Query: 183 SKKAAVTRQEVEMARALVEHMSAQWEPEQFHDTYRDDVLALIQKKIKSRQTHEVAEPDEA 242 +K VT++EV+ A L++ ++ ++P+++ D YR ++ +I+ K +QT E + Sbjct: 183 -EKVDVTKKEVDTALLLIDQLTTTFDPDKYEDDYRQALMEMIENKKAGKQTVTAKEKE-- 239 Query: 243 AVPASSGAKVVDLMALLKSSLE 264 PA+S V DLM L++S++ Sbjct: 240 --PAASN--VTDLMEALQASID 257 >Rv0937c [S] COG1273 Uncharacterized conserved protein Mtu Mycobacterium tuberculosis H37Rv Length = 273 Score = 143 bits (360), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 83/282 (29%), Positives = 156/282 (55%), Gaps = 25/282 (8%) Query: 3 RALWKGAISFGLINIPVELYTAEKHDELDFTLLDQRDLSPVGYKRYNKKSGREVPWENII 62 RA+W G+I+FGL+N+PV++Y+A ++ F + +D + YKR + G V + ++ Sbjct: 2 RAIWTGSIAFGLVNVPVKVYSATADHDIRFHQVHAKDNGRIRYKRVCEACGEVVDYRDLA 61 Query: 63 KGYQYEEGKYVLMSDEDLRRANVEATQSIDIQSFVEREQVPILYYEQPYFLAPAKGGDKA 122 + Y+ +G+ V ++D+D+ E ++ I++ FV V + +++ YFL P K+ Sbjct: 62 RAYESGDGQMVAITDDDIASLPEERSREIEVLEFVPAADVDPMMFDRSYFLEPDSKSSKS 121 Query: 123 YALLRETLLASDKMAIAQIVIRTRQHLAAL----IPQGDMLQLITLRYPSELRAPDDLPV 178 Y LL +TL +D+MAI +R + LAAL + +++ + TL +P E+R P D PV Sbjct: 122 YVLLAKTLAETDRMAIVHFTLRNKTRLAALRVKDFGKREVMMVHTLLWPDEIRDP-DFPV 180 Query: 179 PTRKSKKAAVTRQEVEMARALVEHMSAQWEPEQFHDTYRDDVLALIQKKIKSRQTHE--- 235 +K + E++MA +V+ M+ + P+++HDTY++ + LI K++ Q Sbjct: 181 ---LDQKVEIKPAELKMAGQVVDSMADDFNPDRYHDTYQEQLQELIDTKLEGGQAFTAED 237 Query: 236 ----VAEPDEAAVPASSGAKVVDLMALLKSSLEGRGKSSAKA 273 + EP++ V DL+A L++S++ R K+++ Sbjct: 238 QPRLLDEPED----------VSDLLAKLEASVKARSKANSNV 269 >MT0964 [S] COG1273 Uncharacterized conserved protein MtC Mycobacterium tuberculosis CDC1551 Length = 273 Score = 143 bits (360), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 83/282 (29%), Positives = 156/282 (55%), Gaps = 25/282 (8%) Query: 3 RALWKGAISFGLINIPVELYTAEKHDELDFTLLDQRDLSPVGYKRYNKKSGREVPWENII 62 RA+W G+I+FGL+N+PV++Y+A ++ F + +D + YKR + G V + ++ Sbjct: 2 RAIWTGSIAFGLVNVPVKVYSATADHDIRFHQVHAKDNGRIRYKRVCEACGEVVDYRDLA 61 Query: 63 KGYQYEEGKYVLMSDEDLRRANVEATQSIDIQSFVEREQVPILYYEQPYFLAPAKGGDKA 122 + Y+ +G+ V ++D+D+ E ++ I++ FV V + +++ YFL P K+ Sbjct: 62 RAYESGDGQMVAITDDDIASLPEERSREIEVLEFVPAADVDPMMFDRSYFLEPDSKSSKS 121 Query: 123 YALLRETLLASDKMAIAQIVIRTRQHLAAL----IPQGDMLQLITLRYPSELRAPDDLPV 178 Y LL +TL +D+MAI +R + LAAL + +++ + TL +P E+R P D PV Sbjct: 122 YVLLAKTLAETDRMAIVHFTLRNKTRLAALRVKDFGKREVMMVHTLLWPDEIRDP-DFPV 180 Query: 179 PTRKSKKAAVTRQEVEMARALVEHMSAQWEPEQFHDTYRDDVLALIQKKIKSRQTHE--- 235 +K + E++MA +V+ M+ + P+++HDTY++ + LI K++ Q Sbjct: 181 ---LDQKVEIKPAELKMAGQVVDSMADDFNPDRYHDTYQEQLQELIDTKLEGGQAFTAED 237 Query: 236 ----VAEPDEAAVPASSGAKVVDLMALLKSSLEGRGKSSAKA 273 + EP++ V DL+A L++S++ R K+++ Sbjct: 238 QPRLLDEPED----------VSDLLAKLEASVKARSKANSNV 269 >SMb20686 [S] COG1273 Uncharacterized conserved protein Sme Sinorhizobium meliloti Length = 294 Score = 132 bits (332), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 80/265 (30%), Positives = 146/265 (55%), Gaps = 18/265 (6%) Query: 3 RALWKGAISFGLINIPVELYTAEKHDE-LDFTLLDQRDLSPVGYKRYNKKSGREVPWENI 61 RA WKG I L++ PV LY A E + F L + + + K + + G V ++ Sbjct: 4 RASWKGYIRLSLVSCPVRLYPATSASERISFNQLHKDTHNRINMKPVDPELGL-VERSDL 62 Query: 62 IKGYQYEEGKYVLMSDEDLRRANVEATQSIDIQSFVEREQVPILYYEQPYFLAP-AKGGD 120 +KGY+YE+ KY+++ D DL +E+ +++I++FV+ V ++Y + PY+LAP + Sbjct: 63 VKGYEYEDKKYIIIEDSDLESVRIESNHTMNIEAFVDAGSVDVIYQDAPYYLAPDGAMAE 122 Query: 121 KAYALLRETLLASDKMAIAQIVIRTRQHLAALIPQGDMLQLITLRYPSELRAPDDL--PV 178 + + +LRE L S K+AIA++V+ +R+ + + P+ + + TLR P+E+R D + Sbjct: 123 ETFVVLREALRRSGKLAIARLVLSSRERVVTIGPRETGMFVCTLRNPNEVRGTADYFGNI 182 Query: 179 PTRKSKKAAVTRQEVEMARALVEHMSAQWEPEQFHDTYRDDVLALIQKKIKSRQTHEVAE 238 P K + +++A AL+E + ++P+Q+ D Y ++ +I++K+K + Sbjct: 183 PVGKPDP-----EMLQLAEALIEQKTTTFDPKQYEDRYEVALMQMIREKLKGHKPIIAQA 237 Query: 239 PDEAAVPASSGAKVVDLMALLKSSL 263 P+ VV+LM LK+SL Sbjct: 238 PER--------GNVVNLMDALKASL 254 >mll2074 Non COG Length = 302 Score = 129 bits (325), Expect = 7e-30, Method: Compositional matrix adjust. Identities = 78/265 (29%), Positives = 150/265 (56%), Gaps = 18/265 (6%) Query: 3 RALWKGAISFGLINIPVELYTAEKHDE-LDFTLLDQRDLSPVGYKRYNKKSGREVPWENI 61 RA WKG + L++ PV LY A E + F L ++ + + K + + G V ++ Sbjct: 4 RASWKGYLKLSLVSCPVRLYPATTTSERISFNQLHKKTHNRINMKPVDPELGL-VERSDL 62 Query: 62 IKGYQYEEGKYVLMSDEDLRRANVEATQSIDIQSFVEREQVPILYYEQPYFLAP-AKGGD 120 +KGY+YE+ +Y+++ D DL +E+ +++I++FV+ +V ++Y + PY+LAP + Sbjct: 63 VKGYEYEDKQYIIIDDADLDTVRIESNHTMNIEAFVDEGEVDVIYQDAPYYLAPDGAMAE 122 Query: 121 KAYALLRETLLASDKMAIAQIVIRTRQHLAALIPQGDMLQLITLRYPSELRAPDDL--PV 178 + +A+LRE + S K+AIA++V+ +R+ + + + + + + TLR P+E+R + + Sbjct: 123 ETFAVLREAMRKSGKLAIARLVLSSRERVVTIGARENGMFVCTLRNPNEVRGTAEYFGNI 182 Query: 179 PTRKSKKAAVTRQEVEMARALVEHMSAQWEPEQFHDTYRDDVLALIQKKIKSRQTHEVAE 238 P K + +E+A AL++ ++P+ + D Y ++A+I++K+K + Sbjct: 183 PAGKPDP-----EMLELAEALIKQKETTFDPKDYEDRYEIALMAMIREKLKGHK------ 231 Query: 239 PDEAAVPASSGAKVVDLMALLKSSL 263 P AA P V++LM LK+SL Sbjct: 232 PIIAAAPER--GNVINLMDALKASL 254 >SMb21407 [S] COG1273 Uncharacterized conserved protein Sme Sinorhizobium meliloti Length = 272 Score = 117 bits (293), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 75/264 (28%), Positives = 141/264 (53%), Gaps = 7/264 (2%) Query: 3 RALWKGAISFGLINIPVELYTAEKHDE-LDFTLLDQRDLSPVGYKRYNKKSGREVPWENI 61 R WKG + L+ PV + A E + F L+++ + V + + +G+EV ++ Sbjct: 5 RPYWKGYLKLSLVTCPVSMMPATSESEKVRFHTLNRKSNNRVVSRYVDAVTGKEVDEDDE 64 Query: 62 IKGYQYEEGKYVLMSDEDLRRANVEATQSIDIQSFVEREQVPILYYEQPYFLAPA-KGGD 120 +KGY+ E ++++ DE+L +E+ ++IDI+ FV R+ + ++ E+P++L P+ + G Sbjct: 65 VKGYERGENDFLVIEDEELESVALESARTIDIEKFVPRDTIEWIWLEKPHYLTPSDEVGH 124 Query: 121 KAYALLRETLLASDKMAIAQIVIRTRQHLAALIPQGDMLQLITLRYPSELRAPDDLPVPT 180 +A++++R+ ++A I+++VI R+ L P G + + TLRY E+R P++ Sbjct: 125 EAFSVIRDAMVAEKVAGISRLVIGRRERAVMLEPCGKGIVVWTLRYGDEVRKPENYFADI 184 Query: 181 RKSKKAAVTRQEVEMARALVEHMSAQWEPEQFHDTYRDDVLALIQKKIKSRQTHEVAEPD 240 + + + +L+E S W P D ++ +L +I+ K KS + + Sbjct: 185 GDGDNDP---KLMSLVTSLIEERSKPWNPNMVSDPVQEKLLEIIESKRKSAKKVAKPKAK 241 Query: 241 EAAVPASSGAKVVDLMALLKSSLE 264 E P +G V+DLMA LK SLE Sbjct: 242 EGE-PVHAG-NVIDLMAALKGSLE 263 >AGpA66 [S] COG1273 Uncharacterized conserved protein Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 270 Score = 115 bits (287), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 75/270 (27%), Positives = 146/270 (54%), Gaps = 6/270 (2%) Query: 3 RALWKGAISFGLINIPVELYTAEKHDE-LDFTLLDQRDLSPVGYKRYNKKSGREVPWENI 61 R WKG + L+ PV++ A E + F L++ + V + +G+EV E+ Sbjct: 4 RPYWKGYLKLSLVTCPVQMMPATSESEKVRFHTLNRETQNRVVSHYVDSVTGKEVKDEDE 63 Query: 62 IKGYQYEEGKYVLMSDEDLRRANVEATQSIDIQSFVEREQVPILYYEQPYFLAPAKG-GD 120 +KGYQ E +Y+++ DE+L +++T++IDI +F R+ V ++ + PY+L+P G Sbjct: 64 VKGYQRGENEYIILEDEELENVALDSTKTIDISTFTPRDSVEWIWLDTPYYLSPNDPVGQ 123 Query: 121 KAYALLRETLLASDKMAIAQIVIRTRQHLAALIPQGDMLQLITLRYPSELRAPDDLPVPT 180 +A++++R+ + A + + I+++VI R+ L P+G + L TLRY E+R D Sbjct: 124 EAFSVIRDAMEAQNMVGISRLVISRRERAVMLEPRGKGIVLWTLRYGDEVRDEDTYFAGI 183 Query: 181 RKSKKAAVTRQEVEMARALVEHMSAQWEPEQFHDTYRDDVLALIQKKIKSRQTHEVAEPD 240 + A R+ + + + L++ + W+ + D ++ +L +I K K+ + A+P Sbjct: 184 DDEETA--DREMMPLVQQLIKKQTKHWDAKMVIDPVQERLLDIIAAKKKALKKSARAKP- 240 Query: 241 EAAVPASSGAKVVDLMALLKSSLEGRGKSS 270 +A S+ + V+++M LK S+ +SS Sbjct: 241 -SAPAKSTPSNVINIMDALKKSVAAENRSS 269