BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0001.p (370 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Z2771 [L] COG0322 Nuclease subunit of the excinuclease complex E... 198 1e-50 ECs2447 [L] COG0322 Nuclease subunit of the excinuclease complex... 198 1e-50 ydjQ [L] COG0322 Nuclease subunit of the excinuclease complex Ec... 198 1e-50 STM1309 [L] COG0322 Nuclease subunit of the excinuclease complex... 182 1e-45 CAC3468 [L] COG0322 Nuclease subunit of the excinuclease complex... 81 4e-15 CPn0940 [L] COG0322 Nuclease subunit of the excinuclease complex... 79 2e-14 CC2881 [L] COG0322 Nuclease subunit of the excinuclease complex ... 74 7e-13 MTH441 [L] COG0322 Nuclease subunit of the excinuclease complex ... 71 5e-12 CT791 [L] COG0322 Nuclease subunit of the excinuclease complex C... 70 7e-12 NMA1540 [L] COG0322 Nuclease subunit of the excinuclease complex... 70 1e-11 >Z2771 [L] COG0322 Nuclease subunit of the excinuclease complex EcZ Escherichia coli O157:H7 EDL933 Length = 295 Score = 198 bits (504), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 115/289 (39%), Positives = 172/289 (59%), Gaps = 10/289 (3%) Query: 77 FNAPQPAAHRAATFSYPLHIDRASIEALPSACGVYILRGEGDQA-LYVGRSVNLRSRVLA 135 +P+ AA + YP H+ R+ + LP+ GVY+ GE D LY+G+SVN+RSRVL+ Sbjct: 5 LTSPRLEFEAAAIYEYPEHL-RSFLNDLPTRPGVYLFHGESDTMPLYIGKSVNIRSRVLS 63 Query: 136 HLHHAEDQFLIGRTRRIECLRTAGELGAALLENSLLRDLRPAHNKKQRAKRSLFTLRLDE 195 HL ++ ++ ++RRI + TAGE+GA LLE L+++ +P NK+ R R L L+L+E Sbjct: 64 HLRTPDEAAMLRQSRRISWICTAGEIGALLLEARLIKEQQPLFNKRLRRNRQLCALQLNE 123 Query: 196 QGQPLVAQVADHEFNRAGKLFGLYTSERAAQEALHKLVEHHGLCSIATGLEQGEGPGMAC 255 + +V + +F+RA LFGL+ + RAA +AL + + LC GLE G AC Sbjct: 124 KRVDVV-YAKEVDFSRAPNLFGLFANRRAALQALQSIADEQKLCYGLLGLEPL-SRGRAC 181 Query: 256 FGRQIRRCRGACTGEESHEQHQSRLLQALEDLRILPWPYAGPMGIVEQGDGWQQIHVIDQ 315 F ++RC GAC G+ESHE+H RL Q+LE LR++ WP+ G + + EQ Q H+I Sbjct: 182 FRSALKRCAGACCGKESHEEHALRLRQSLERLRVVCWPWQGAVALKEQHPEMTQYHIIQN 241 Query: 316 WRYLGSLD--RQQRRLPARPAASLKGFDLDTYKLVIQPYLLGQLELRPL 362 W +LG+++ + L PA GFD D YK++ +P L G E+ L Sbjct: 242 WLWLGAVNSLEEATTLIRTPA----GFDHDGYKILCKPLLSGNYEITEL 286 >ECs2447 [L] COG0322 Nuclease subunit of the excinuclease complex Ecs Escherichia coli O157:H7 Length = 295 Score = 198 bits (504), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 115/289 (39%), Positives = 172/289 (59%), Gaps = 10/289 (3%) Query: 77 FNAPQPAAHRAATFSYPLHIDRASIEALPSACGVYILRGEGDQA-LYVGRSVNLRSRVLA 135 +P+ AA + YP H+ R+ + LP+ GVY+ GE D LY+G+SVN+RSRVL+ Sbjct: 5 LTSPRLEFEAAAIYEYPEHL-RSFLNDLPTRPGVYLFHGESDTMPLYIGKSVNIRSRVLS 63 Query: 136 HLHHAEDQFLIGRTRRIECLRTAGELGAALLENSLLRDLRPAHNKKQRAKRSLFTLRLDE 195 HL ++ ++ ++RRI + TAGE+GA LLE L+++ +P NK+ R R L L+L+E Sbjct: 64 HLRTPDEAAMLRQSRRISWICTAGEIGALLLEARLIKEQQPLFNKRLRRNRQLCALQLNE 123 Query: 196 QGQPLVAQVADHEFNRAGKLFGLYTSERAAQEALHKLVEHHGLCSIATGLEQGEGPGMAC 255 + +V + +F+RA LFGL+ + RAA +AL + + LC GLE G AC Sbjct: 124 KRVDVV-YAKEVDFSRAPNLFGLFANRRAALQALQSIADEQKLCYGLLGLEPL-SRGRAC 181 Query: 256 FGRQIRRCRGACTGEESHEQHQSRLLQALEDLRILPWPYAGPMGIVEQGDGWQQIHVIDQ 315 F ++RC GAC G+ESHE+H RL Q+LE LR++ WP+ G + + EQ Q H+I Sbjct: 182 FRSALKRCAGACCGKESHEEHALRLRQSLERLRVVCWPWQGAVALKEQHPEMTQYHIIQN 241 Query: 316 WRYLGSLD--RQQRRLPARPAASLKGFDLDTYKLVIQPYLLGQLELRPL 362 W +LG+++ + L PA GFD D YK++ +P L G E+ L Sbjct: 242 WLWLGAVNSLEEATTLIRTPA----GFDHDGYKILCKPLLSGNYEITEL 286 >ydjQ [L] COG0322 Nuclease subunit of the excinuclease complex Eco Escherichia coli K12 Length = 295 Score = 198 bits (504), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 115/289 (39%), Positives = 172/289 (59%), Gaps = 10/289 (3%) Query: 77 FNAPQPAAHRAATFSYPLHIDRASIEALPSACGVYILRGEGDQA-LYVGRSVNLRSRVLA 135 +P+ AA + YP H+ R+ + LP+ GVY+ GE D LY+G+SVN+RSRVL+ Sbjct: 5 LTSPRLEFEAAAIYEYPEHL-RSFLNDLPTRPGVYLFHGESDTMPLYIGKSVNIRSRVLS 63 Query: 136 HLHHAEDQFLIGRTRRIECLRTAGELGAALLENSLLRDLRPAHNKKQRAKRSLFTLRLDE 195 HL ++ ++ ++RRI + TAGE+GA LLE L+++ +P NK+ R R L L+L+E Sbjct: 64 HLRTPDEAAMLRQSRRISWICTAGEIGALLLEARLIKEQQPLFNKRLRRNRQLCALQLNE 123 Query: 196 QGQPLVAQVADHEFNRAGKLFGLYTSERAAQEALHKLVEHHGLCSIATGLEQGEGPGMAC 255 + +V + +F+RA LFGL+ + RAA +AL + + LC GLE G AC Sbjct: 124 KRVDVV-YAKEVDFSRAPNLFGLFANRRAALQALQTIADEQKLCYGLLGLEP-LSRGRAC 181 Query: 256 FGRQIRRCRGACTGEESHEQHQSRLLQALEDLRILPWPYAGPMGIVEQGDGWQQIHVIDQ 315 F ++RC GAC G+ESHE+H RL Q+LE LR++ WP+ G + + EQ Q H+I Sbjct: 182 FRSALKRCAGACCGKESHEEHALRLRQSLERLRVVCWPWQGAVALKEQHPEMTQYHIIQN 241 Query: 316 WRYLGSLD--RQQRRLPARPAASLKGFDLDTYKLVIQPYLLGQLELRPL 362 W +LG+++ + L PA GFD D YK++ +P L G E+ L Sbjct: 242 WLWLGAVNSLEEATTLIRTPA----GFDHDGYKILCKPLLSGNYEITEL 286 >STM1309 [L] COG0322 Nuclease subunit of the excinuclease complex Sty Salmonella typhimurium LT2 Length = 302 Score = 182 bits (461), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 111/286 (38%), Positives = 164/286 (57%), Gaps = 12/286 (4%) Query: 78 NAPQPAAHRAATFSYPLHIDRASIEALPSACGVYILRGEGDQA-LYVGRSVNLRSRVLAH 136 +AP+ AA + YP H+ R + P+ GVYI E D LY+G+SVN+RSRVL+H Sbjct: 15 SAPRLEFEAAAIYEYPEHL-RPFLSEAPALPGVYIFHSESDTLPLYIGKSVNIRSRVLSH 73 Query: 137 LHHAEDQFLIGRTRRIECLRTAGELGAALLENSLLRDLRPAHNKKQRAKRSLFTLRLDEQ 196 L ++ ++ + RRI + TAGE+GA LLE L+++ +P NK+ R R L +L+L EQ Sbjct: 74 LRTPDEATMLRQARRISWICTAGEMGALLLEARLIKEQQPLFNKRLRRNRQLCSLQLSEQ 133 Query: 197 GQPLVAQVADHEFNRAGKLFGLYTSERAAQEALHKLVEHHGLCSIATGLEQGEGPGMACF 256 +V+ +F+ LFGL+ + RAA ++L L + LC GLE G ACF Sbjct: 134 KIEVVS-ARSVDFSHEPNLFGLFANRRAALQSLQNLADEQKLCYGLLGLE-PVSRGRACF 191 Query: 257 GRQIRRCRGACTGEESHEQHQSRLLQALEDLRILPWPYAGPMGIVEQGDGWQQIHVIDQW 316 ++RC GAC G+E+ + H RL +LE LR++ WP+ G + + E Q H+I+ W Sbjct: 192 RFALKRCAGACCGQETPQAHFLRLQASLERLRVVCWPWKGAIALKESRPQMTQFHIINNW 251 Query: 317 RYLG---SLDRQQRRLPARPAASLKGFDLDTYKLVIQPYLLGQLEL 359 +LG SLD + L PA GFD D YK++ +P + GQ E+ Sbjct: 252 LWLGAVPSLD-EAATLVRTPA----GFDQDGYKILCKPLMSGQYEI 292 >CAC3468 [L] COG0322 Nuclease subunit of the excinuclease complex Cac Clostridium acetobutylicum Length = 373 Score = 80.9 bits (198), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 58/198 (29%), Positives = 101/198 (51%), Gaps = 19/198 (9%) Query: 98 RASIEALPSACGVYILRGEGDQALYVGRSVNLRSRVLAHL-----HHAEDQFLIGRTRRI 152 + I LPSA GVY+++ + +YVG+S NLRSRV ++ H ++ L+ + Sbjct: 4 KEKIRKLPSAPGVYLMKDSLNTIIYVGKSKNLRSRVQSYFVNSKSHSSKVLKLVKNLKDF 63 Query: 153 ECLRTAGELGAALLENSLLRDLRPAHNKKQRAKR--SLFTLRLDEQGQPLVAQVADHEFN 210 + + T E A LLE L++ ++P +N++ ++ + ++LDE+ P V ++ E Sbjct: 64 DYIVTDTEFEALLLECKLIKRIKPIYNRQMKSPKGYCYIKIKLDEK-YPSVEIKSNDE-- 120 Query: 211 RAGK--LFGLYTSERAAQEALHKLVEHHG-LCSIATGLEQGEGPGMACFGRQIRRCRGAC 267 R G+ FG YTS+ ++AL+ + EH LC+ ++ G C C G C Sbjct: 121 RVGESLYFGPYTSKSTVEKALYGIKEHMKILCTNSSKKASG------CLKYSTGLCLGMC 174 Query: 268 TGEESHEQHQSRLLQALE 285 T S E + S + + +E Sbjct: 175 TANPSFEYYSSLIEKIIE 192 >CPn0940 [L] COG0322 Nuclease subunit of the excinuclease complex Cpn Chlamydophila pneumoniae CWL029 Length = 603 Score = 79.0 bits (193), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 56/204 (27%), Positives = 98/204 (48%), Gaps = 20/204 (9%) Query: 94 LHIDRASIEALPSACGVYILRGEGDQALYVGRSVNLRSRVLAHLHHAEDQ-----FLIGR 148 + I+ S++ +PS+ GVY+++ DQ LY+G++ NL++R+ ++ H D FL+ + Sbjct: 1 MRIEDFSLKLIPSSPGVYLMKDVHDQVLYIGKAKNLKNRLASYFHEKGDSRERIPFLMKK 60 Query: 149 TRRIECLRTAGELGAALLENSLLRDLRPAHNKKQRAKRSLFTLRLD-EQGQPLVAQVADH 207 T IE + + E A LLEN+L++ P +N + ++ F L + P V + Sbjct: 61 TASIETIVVSNETEALLLENNLIKQHHPKYNVLLKDDKTFFCLAISLSHSWPKVEAIRTK 120 Query: 208 EFNRAGK--LFGLYTSERAAQEALHKLVEHHGLCSIATGLEQGEGPGMA-----CFGRQI 260 + + +FG Y S EA H L+E + S L A C + Sbjct: 121 AITSSQRQLIFGPYVS----AEACHTLLE---VISQWFPLRTCSDREFALRKRPCILYDM 173 Query: 261 RRCRGACTGEESHEQHQSRLLQAL 284 +RC C G + E++Q L +A+ Sbjct: 174 KRCLAPCVGYCTPEEYQGTLDKAI 197 >CC2881 [L] COG0322 Nuclease subunit of the excinuclease complex Ccr Caulobacter vibrioides Length = 640 Score = 73.6 bits (179), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 58/197 (29%), Positives = 89/197 (45%), Gaps = 10/197 (5%) Query: 98 RASIEALPSACGVYILRGEGDQALYVGRSVNLRSRVLAH----LHHAEDQFLIGRTRRIE 153 + + LP A GVY + GE D+ LYVG++ +L+ RV+ + H ++ TR +E Sbjct: 27 KDEVTRLPDAPGVYRMIGEADEVLYVGKAKSLKKRVVQYAQGRFHTNRIANMVDATRAME 86 Query: 154 CLRTAGELGAALLENSLLRDLRPAHNKKQRAKRSL--FTLRLDEQGQPLVAQVADHEFNR 211 + T E A LLE +L++ L+P N R +S +R D L H Sbjct: 87 FITTRTEADALLLEINLIKQLKPRFNVLLRDDKSFPEIVIRRDHDAPQLRKHRGAHTIK- 145 Query: 212 AGKLFGLYTSERAAQEALHKLVEHHGLCSIATGLEQGEGPGMACFGRQIRRCRGACTGEE 271 G FG + S A L+ L + L S + + + C QI+RC CTG Sbjct: 146 -GDYFGPFASAWAVNRTLNTLQKAFLLRSCSDSVY--DSRDRPCMLYQIKRCAAPCTGLI 202 Query: 272 SHEQHQSRLLQALEDLR 288 + +Q+ + QA LR Sbjct: 203 GKDDYQALVDQAEAFLR 219 >MTH441 [L] COG0322 Nuclease subunit of the excinuclease complex Mth Methanothermobacter thermautotrophicus Length = 579 Score = 70.9 bits (172), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 52/179 (29%), Positives = 90/179 (50%), Gaps = 11/179 (6%) Query: 102 EALPSACGVYILRGEGDQALYVGRSVNLRSRVLAHLHHAED---QFLIGRTRRIECLRTA 158 E LP A GVYI R D+ LYVG+S+++R RV ++ E+ + ++ IE + T Sbjct: 8 EKLPDATGVYIFRDRDDRVLYVGKSISIRKRVSSYFREQENPRLRIMMRHLESIEYILTQ 67 Query: 159 GELGAALLENSLLRDLRPAHNKKQRAKRSLFTLRLDEQGQPLVAQVADHEFNRAGKLFGL 218 E A +LE++L++ RP +N + + + +++ ++ P V V + A + +G Sbjct: 68 NEKEALILESNLIKRYRPPYNVRLKDDKRYPFIKITDEEYPRVLIVRTIGRDSA-RYYGP 126 Query: 219 YTSERAAQEALHKLVEHHGLCSIATGLEQGEGPGMACFGRQIRRCRGACTGEESHEQHQ 277 +T A + L KL++ L I + + +GP C QI C C G S E ++ Sbjct: 127 FTDTGAVRRTL-KLIK--SLFRIRS-CRRMDGP---CLNSQIDLCYAPCDGRISREDYR 178 >CT791 [L] COG0322 Nuclease subunit of the excinuclease complex Ctr Chlamydia trachomatis Length = 598 Score = 70.1 bits (170), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 54/202 (26%), Positives = 95/202 (47%), Gaps = 15/202 (7%) Query: 94 LHIDRASIEALPSACGVYILRGEGDQALYVGRSVNLRSRVLAHLHHAEDQ-----FLIGR 148 + I+ S++ + S+ GVY+++ LYVG++ NLR+R+ ++L D FL+ + Sbjct: 1 MRIEDFSLKDVSSSPGVYLMKDSQGTVLYVGKAKNLRNRLSSYLQKKGDSRKRIPFLMKK 60 Query: 149 TRRIECLRTAGELGAALLENSLLRDLRPAHNKKQRAKRSLFTLRLD-EQGQPLVAQVADH 207 T I+ + + E A LLEN+L++ +P +N + ++ F L + E P + + Sbjct: 61 TTDIDTIVVSNETEAILLENNLIKKYQPRYNVLLKDDKTFFCLSVSLEHPWPRIEAIRTR 120 Query: 208 EFNRAGK---LFGLYTSERAAQEALHKLVEHHGLCSIATGLEQGEGPGMA--CFGRQIRR 262 + K LFG Y S EA + L+E L E C +++R Sbjct: 121 ALSPGKKKQWLFGPYVS----AEACYALLEVISLWFPLRTCSDREFSTRQRPCVLYEMKR 176 Query: 263 CRGACTGEESHEQHQSRLLQAL 284 C C G S ++Q L +A+ Sbjct: 177 CLAPCVGLCSQTEYQETLDKAV 198 >NMA1540 [L] COG0322 Nuclease subunit of the excinuclease complex NmA Neisseria meningitidis Z2491 Length = 628 Score = 69.7 bits (169), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 56/199 (28%), Positives = 88/199 (44%), Gaps = 14/199 (7%) Query: 90 FSYPLHIDRASIEALPSACGVYILRGEGDQALYVGRSVNLRSRVLAHL----HHAEDQFL 145 F PL + + LP GVY EG + LYVG++VNL+ RV + H + Sbjct: 22 FDIPLFL-----KNLPKLPGVYRFFDEGGKVLYVGKAVNLKRRVSGYFQKNDHSPRIALM 76 Query: 146 IGRTRRIECLRTAGELGAALLENSLLRDLRPAHNKKQRAKRSLFTLRLDEQGQPLVAQVA 205 + + IE T E A +LEN+ ++ L P +N R +S L L P +A Sbjct: 77 VKQVHHIETTITRSEAEALILENNFIKALSPKYNILFRDDKSYPYLMLSGHQYPQMAYYR 136 Query: 206 DHEFNRAGKLFGLYTSERAAQEALHKLVEHHGLCSIATGL-EQGEGPGMACFGRQIRRCR 264 + + FG Y + A ++++ L + L + + E + P C QI+RC Sbjct: 137 G-TLKKPNQYFGPYPNSNAVRDSIQILQKVFMLRTCEDSVFEHRDRP---CLLYQIKRCT 192 Query: 265 GACTGEESHEQHQSRLLQA 283 C G S E ++ + QA Sbjct: 193 APCVGHISEEDYRDSVRQA 211