BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0026.0044.p (302 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2206 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 195 9e-50 Z3395 [K] COG0583 Transcriptional regulator EcZ Escherichia coli... 153 5e-37 ECs3032 [K] COG0583 Transcriptional regulator Ecs Escherichia co... 153 5e-37 AGc4269 [K] COG0583 Transcriptional regulator Atu Agrobacterium ... 140 3e-33 mlr5660 [K] COG0583 Transcriptional regulator Mlo Mesorhizobium ... 133 5e-31 STM2180 [K] COG0583 Transcriptional regulator Sty Salmonella typ... 132 8e-31 SMb20896 [K] COG0583 Transcriptional regulator Sme Sinorhizobium... 110 3e-24 PA2469 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 104 2e-22 SMb20580 [K] COG0583 Transcriptional regulator Sme Sinorhizobium... 102 1e-21 RSc1440 [K] COG0583 Transcriptional regulator Rso Ralstonia sola... 98 3e-20 >PA2206 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 315 Score = 195 bits (496), Expect = 9e-50, Method: Compositional matrix adjust. Identities = 101/277 (36%), Positives = 169/277 (61%), Gaps = 1/277 (0%) Query: 20 DEQGSLHKAAEVMHMTQPAATKALHEMEDALGVTLFDRSPRGIEATELGRCVIRYARLIQ 79 +E GSL +AA+ + MTQPAATK LHE ED LGV LF+R PRG+ AT G +I Y+R+I Sbjct: 26 EELGSLRRAADEIGMTQPAATKMLHEAEDLLGVELFERLPRGMRATPFGETLIYYSRMIF 85 Query: 80 SDVANLRDELQNMISGRGGRLAIGTIMG-AAPFVTRALSRLREIQPEVSIEISEDTSARQ 138 ++++ +R+EL + SG GR+ +G I A+ +TR ++ L++ P +S+ I DTS Sbjct: 86 AELSGMREELVALESGNLGRVTVGAIPALASSLLTRTIATLKQSHPRLSMSIQVDTSDVL 145 Query: 139 LLLLDQGRIDLMIGRSSVSSQPNLYHYEMLRGEPMCIVSGIDHPLATAQKVRLQELAEAS 198 + L Q ++D+++GR ++ + ++ L E +C+V G +PL+ A+K+ EL E + Sbjct: 146 VQALQQDQLDVVLGRIPSGARTDDLVFDSLGEEELCVVVGAQNPLSQARKLDWGELQELT 205 Query: 199 WILYSSNMPMRIWIEHEFKLEGVKVPGNVIETASPFVTITLLAQSNMVAVMPLDIAHFFA 258 W+L PMR + F + +P +++ET S ++LL Q++M+ + P + + Sbjct: 206 WVLQQHPSPMRGIVNQAFHNARIDLPSSIVETTSIMTLLSLLQQTDMIGITPRSVIEDYP 265 Query: 259 AKQMLGILPVNLKTRIEHYGIVTRKNTTLSSLAKMFI 295 K +L ILP+ L+ R+ YG++TR+N SS + F+ Sbjct: 266 GKHLLAILPIQLEPRLPPYGLITRRNRVHSSAMQTFM 302 >Z3395 [K] COG0583 Transcriptional regulator EcZ Escherichia coli O157:H7 EDL933 Length = 318 Score = 153 bits (386), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 94/295 (31%), Positives = 161/295 (54%), Gaps = 1/295 (0%) Query: 7 RLRFRQVALLTALDEQGSLHKAAEVMHMTQPAATKALHEMEDALGVTLFDRSPRGIEATE 66 +L+ + +L AL EQG+L A +M++TQPA +K L ++ED +G+TLF+R +G+ TE Sbjct: 23 KLKLHHLEMLVALGEQGNLTHVARMMNITQPALSKWLSQLEDEIGITLFERHSKGLRPTE 82 Query: 67 LGRCVIRYARLIQSDVANLRDELQNMI-SGRGGRLAIGTIMGAAPFVTRALSRLREIQPE 125 G+ ++++A+ + +D+ + EL G G L IG A V++A+ L P Sbjct: 83 GGKLLLQHAQRLINDMERSQHELARFKQGGLVGSLKIGCSPVATDCVSQAILHLLTKMPT 142 Query: 126 VSIEISEDTSARQLLLLDQGRIDLMIGRSSVSSQPNLYHYEMLRGEPMCIVSGIDHPLAT 185 + + I E L L G +D+++GR + +Y++L EP+C V+ +HPLA Sbjct: 143 LHLNIEEKVMTPLLQDLLAGSVDVVVGRIGGRALQLPLNYQVLYTEPVCFVARPEHPLAK 202 Query: 186 AQKVRLQELAEASWILYSSNMPMRIWIEHEFKLEGVKVPGNVIETASPFVTITLLAQSNM 245 + +LA WI++ + P+RI I++ GV +P N IE+AS V+ LL S+M Sbjct: 203 YATLSWNDLANWRWIVWPTGTPIRISIDNALVDHGVMLPENTIESASMNVSTNLLQSSDM 262 Query: 246 VAVMPLDIAHFFAAKQMLGILPVNLKTRIEHYGIVTRKNTTLSSLAKMFIQILRQ 300 ++++ L +A +A++ L IL + + G+ R N T S F+ L+Q Sbjct: 263 ISILSLRLAQRYASQGQLVILNLPKIEQKGSVGVFWRNNETPSYALSQFLHFLQQ 317 >ECs3032 [K] COG0583 Transcriptional regulator Ecs Escherichia coli O157:H7 Length = 318 Score = 153 bits (386), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 94/295 (31%), Positives = 161/295 (54%), Gaps = 1/295 (0%) Query: 7 RLRFRQVALLTALDEQGSLHKAAEVMHMTQPAATKALHEMEDALGVTLFDRSPRGIEATE 66 +L+ + +L AL EQG+L A +M++TQPA +K L ++ED +G+TLF+R +G+ TE Sbjct: 23 KLKLHHLEMLVALGEQGNLTHVARMMNITQPALSKWLSQLEDEIGITLFERHSKGLRPTE 82 Query: 67 LGRCVIRYARLIQSDVANLRDELQNMI-SGRGGRLAIGTIMGAAPFVTRALSRLREIQPE 125 G+ ++++A+ + +D+ + EL G G L IG A V++A+ L P Sbjct: 83 GGKLLLQHAQRLINDMERSQHELARFKQGGLVGSLKIGCSPVATDCVSQAILHLLTKMPT 142 Query: 126 VSIEISEDTSARQLLLLDQGRIDLMIGRSSVSSQPNLYHYEMLRGEPMCIVSGIDHPLAT 185 + + I E L L G +D+++GR + +Y++L EP+C V+ +HPLA Sbjct: 143 LHLNIEEKVMTPLLQDLLAGSVDVVVGRIGGRALQLPLNYQVLYTEPVCFVARPEHPLAK 202 Query: 186 AQKVRLQELAEASWILYSSNMPMRIWIEHEFKLEGVKVPGNVIETASPFVTITLLAQSNM 245 + +LA WI++ + P+RI I++ GV +P N IE+AS V+ LL S+M Sbjct: 203 YATLSWNDLANWRWIVWPTGTPIRISIDNALVDHGVMLPENTIESASMNVSTNLLQSSDM 262 Query: 246 VAVMPLDIAHFFAAKQMLGILPVNLKTRIEHYGIVTRKNTTLSSLAKMFIQILRQ 300 ++++ L +A +A++ L IL + + G+ R N T S F+ L+Q Sbjct: 263 ISILSLRLAQRYASQGQLVILNLPKIEQKGSVGVFWRNNETPSYALSQFLHFLQQ 317 >AGc4269 [K] COG0583 Transcriptional regulator Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 341 Score = 140 bits (354), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 96/300 (32%), Positives = 149/300 (49%), Gaps = 13/300 (4%) Query: 8 LRFRQVALLTALDEQGSLHKAAEVMHMTQPAATKALHEMEDALGVTLFDRSPRGIEATEL 67 L+ + +L ++E G + AA M+MTQPAA++ L EME + L R+ RG+ T+ Sbjct: 36 LKMSHLRMLVMIEEHGQVSAAAAAMNMTQPAASRMLSEMEAIVKSPLCQRASRGVVLTKF 95 Query: 68 GRCVIRYARLIQSDVANLRDELQNMISGRGGRLAIGTIMGAA-----PFVTRALSRLREI 122 G + R AR I ++ EL M SG GG + IG + A P + RA+ I Sbjct: 96 GEALARRARTILLELREASRELNQMKSGSGGSVYIGAVTAPAISLVVPAIRRAMDTYPGI 155 Query: 123 QPEVSIEISEDTSARQLLLLDQGRIDLMIGRSSVSSQPNLYHYEMLRGEPMCIVSGIDHP 182 + V +E S + AR+LL R D +IGR P L+ + E C+V HP Sbjct: 156 EINVQVE-SSNVLARELL---AARHDFIIGRIPDDFDPGLFSIHEIGIERACLVVREGHP 211 Query: 183 LATAQKVRLQELAEASWILYSSNMPMRIWIEHEFKLEGVKVPGNVIETASPFVTITLLAQ 242 L + V LQ+L+ W+ +R +E F GV +P NVI T S +T+ L+ Sbjct: 212 LMRGEPVTLQDLSGYDWVFQPPGALLRRTMEDVFLTHGVAMPRNVINTPSVVLTLALVCN 271 Query: 243 SNMVAVMPLDIAHFFAAKQM-LG---ILPVNLKTRIEHYGIVTRKNTTLSSLAKMFIQIL 298 +N +A + D+A F A +Q +G ILP + + ++ Y I+T K L A++ ++ Sbjct: 272 TNAIAPIAQDMAEFVAGQQADIGRTRILPTDFELVVKPYSIITTKGRVLPPSARLLYDLV 331 >mlr5660 [K] COG0583 Transcriptional regulator Mlo Mesorhizobium loti Length = 296 Score = 133 bits (335), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 87/290 (30%), Positives = 151/290 (52%), Gaps = 15/290 (5%) Query: 15 LLTALDEQGSLHKAAEVMHMTQPAATKALHEMEDALGVTLFDRSPRGIEATELGRCVIRY 74 ++ ALD+ G + AA+VM+++QPAA++ + EME L V L DR PRGI T G+ + R Sbjct: 3 MIVALDDHGRVSAAAQVMNISQPAASRMIAEMEAVLEVKLCDRLPRGITLTPYGKALARR 62 Query: 75 ARLIQSDVANLRDELQNMISGRGGRLAIGTIMGAAPFVTRALSRLREIQ---PEVSIEIS 131 R I ++ + E+ + +G+GG + +G + AP + A+ +REI+ P + I + Sbjct: 63 GRSILLEMREVDREISELKAGKGGSVFLGAV--TAPAIELAVPAIREIRRIYPRIEITMQ 120 Query: 132 EDTS---ARQLLLLDQGRIDLMIGRSSVSSQPNLYHYEMLRGEPMCIVSGIDHPLATAQK 188 +TS AR+L+ R D +I R P L+ ++ E C++ HPL + Sbjct: 121 VETSNVLARELI---ASRHDFIIARIPDDLNPRLFESRVIGVEKACLIVRRGHPLTSGSV 177 Query: 189 VRLQELAEASWILYSSNMPMRIWIEHEFKLEGVKVPGNVIETASPFVTITLLAQSNMVAV 248 VRL++ A W+ S P+R +E F + +P ++ T+S +T+ ++AQS+ +A Sbjct: 178 VRLEDTAAYDWVFQSGGSPLRQAMESNFLNRNIALPDRILNTSSLLLTLVMVAQSDAIAP 237 Query: 249 MPLDIAHFFAAKQMLG----ILPVNLKTRIEHYGIVTRKNTTLSSLAKMF 294 + + +A F L ++ + Y ++T +N LS AKM Sbjct: 238 VSVQVAKFIQNPDGLAGAIDVVQTEFDIEVRPYSLITVRNRALSPAAKML 287 >STM2180 [K] COG0583 Transcriptional regulator Sty Salmonella typhimurium LT2 Length = 302 Score = 132 bits (333), Expect = 8e-31, Method: Compositional matrix adjust. Identities = 91/296 (30%), Positives = 157/296 (53%), Gaps = 3/296 (1%) Query: 7 RLRFRQVALLTALDEQGSLHKAAEVMHMTQPAATKALHEMEDALGVTLFDRSPRGIEATE 66 +L+ + L AL EQG+L A +M+++QPA +K L ++ED +G+TLF+R +G+ +E Sbjct: 7 KLKLHHLQTLVALGEQGNLTHVARMMNISQPALSKWLSQLEDEIGITLFERHSKGLRPSE 66 Query: 67 LGRCVIRYARLIQSDVANLRDELQNMI-SGRGGRLAIGTIMGAAPFVTRALSRLREIQPE 125 G+ ++++A+ + +D+ + E+ G G L IG A V++A+ L P Sbjct: 67 GGKLLLQHAQRLINDLERSQYEIARFKQGGLVGSLKIGCSPVATDCVSQAILSLLNEMPT 126 Query: 126 VSIEISEDTSARQLL-LLDQGRIDLMIGRSSVSSQPNLYHYEMLRGEPMCIVSGIDHPLA 184 + + I E L LL ++ + Q L +Y++L EP+C V+ HPLA Sbjct: 127 LHLNIEEKVMTPLLHDLLAGQVDVVVGRVGGRALQLPL-NYQVLYTEPVCFVARPHHPLA 185 Query: 185 TAQKVRLQELAEASWILYSSNMPMRIWIEHEFKLEGVKVPGNVIETASPFVTITLLAQSN 244 ++ +LA WI++ + P+RI I++ GV +P N IE+AS V+ LL S+ Sbjct: 186 ARAQIAWSDLAHWRWIVWPTGTPIRISIDNALVDNGVMLPENTIESASMNVSTNLLQSSD 245 Query: 245 MVAVMPLDIAHFFAAKQMLGILPVNLKTRIEHYGIVTRKNTTLSSLAKMFIQILRQ 300 M++++ L +A +A++ L IL + + G+ RKN T S F+ L Q Sbjct: 246 MISILSLRLAQRYASQGQLAILNLPKIEQKGSVGMFWRKNETPSLALSRFLYFLAQ 301 >SMb20896 [K] COG0583 Transcriptional regulator Sme Sinorhizobium meliloti Length = 302 Score = 110 bits (275), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 80/305 (26%), Positives = 151/305 (49%), Gaps = 15/305 (4%) Query: 8 LRFRQVALLTALDEQGSLHKAAEVMHMTQPAATKALHEMEDALGVTLFDRSPRGIEATEL 67 ++ + L+ A+D+ + AA+ + ++QPAA++ L E+E + + +R RG+E T Sbjct: 1 MKINHLRLILAIDDHRRISAAADSLGISQPAASRMLAEIEAIVKAPICERVARGVELTRY 60 Query: 68 GRCVIRYARLIQSDVANLRDELQNMISGRGGRLAIGTIMGAAPFVTRALSRLREIQ---P 124 G + R AR I ++ E+ + +G GG +++G++ G P + A+ +R++ P Sbjct: 61 GEALARRARTIFLELREAAREINELKTGSGGSVSLGSVTG--PGLNLAVPAIRQVSTAYP 118 Query: 125 EVSIEISEDTS---ARQLLLLDQGRIDLMIGRSSVSSQPNLYHYEMLRGEPMCIVSGIDH 181 + I + D S R+LL R D ++GR P L++ + E +C++ H Sbjct: 119 GIEINVQIDNSNVLTRELL---AARHDFIVGRIPDDLNPRLFNLVEIGFEEVCLIVREGH 175 Query: 182 PLATAQKVRLQELAEASWILYSSNMPMRIWIEHEFKLEGVKVPGNVIETASPFVTITLLA 241 PL +L W+ +R +E F GV++P VI T+S +T++++ Sbjct: 176 PLLDKASASAHDLPAYDWVFQPPGTLLRRAVEDSFASAGVRLPATVINTSSTILTLSIVR 235 Query: 242 QSNMVAVMPLDIAHFFAAKQM----LGILPVNLKTRIEHYGIVTRKNTTLSSLAKMFIQI 297 +N +A + LD+A A + ILP RI+ YG++T + L AK+ + Sbjct: 236 NTNAIAPVALDVARLVAGNGTEAGEIRILPTEFPIRIKPYGLITAEGRALPPSAKLLYDL 295 Query: 298 LRQQN 302 + +Q+ Sbjct: 296 ILKQS 300 >PA2469 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 304 Score = 104 bits (260), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 67/232 (28%), Positives = 118/232 (50%), Gaps = 1/232 (0%) Query: 18 ALDEQGSLHKAAEVMHMTQPAATKALHEMEDALGVTLFDRSPRGIEATELGRCVIRYARL 77 +L E G+L A H TQP +K L E+E+ +G LF+R RG+ T G + +A+ Sbjct: 17 SLMETGNLSGTARAAHTTQPGLSKWLKELEEDVGAPLFERHARGLRPTPYGMTLFNHAQR 76 Query: 78 IQSDVANLRDELQNMISGRGGRLAIGTIMGAAP-FVTRALSRLREIQPEVSIEISEDTSA 136 + +++ R L+ M SG G R+ +GT +AP V RAL P +E+ E T Sbjct: 77 VLTEMERARQNLEAMRSGSGSRVLLGTSPASAPSLVPRALRAFLGRYPGAQVELLEGTMN 136 Query: 137 RQLLLLDQGRIDLMIGRSSVSSQPNLYHYEMLRGEPMCIVSGIDHPLATAQKVRLQELAE 196 L L++ ++D+++GR + E+L E + +++ HPLA A + +++ Sbjct: 137 GLLERLEKRQLDVVVGRLDNYAPRASLRCEVLYSEAIVVMARPGHPLAQAAALDWEDVRR 196 Query: 197 ASWILYSSNMPMRIWIEHEFKLEGVKVPGNVIETASPFVTITLLAQSNMVAV 248 WI++ P+R ++ G + P +E++S I LL S+M+++ Sbjct: 197 YDWIVWPPGSPIRSKLDMALTQGGRQPPAYRLESSSMLANIELLRGSDMLSI 248 >SMb20580 [K] COG0583 Transcriptional regulator Sme Sinorhizobium meliloti Length = 313 Score = 102 bits (253), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 82/308 (26%), Positives = 144/308 (46%), Gaps = 21/308 (6%) Query: 4 IVSRLRFRQVALLTALDEQGSLHKAAEVMHMTQPAATKALHEMEDALGVTLFDRSPRGIE 63 I +R++FR + + Q S+ KAAE++H+TQPA TK + E+E+ LGV +F+R RGI+ Sbjct: 2 IDARVKFRHLQTFVEVARQKSVVKAAELLHVTQPAVTKTIRELEEVLGVAVFEREGRGIK 61 Query: 64 ATELGRCVIRYARLIQSDVANLRDELQNMISGRGGRLAIGTIMGAAPFV-TRALSRLREI 122 T G +R+A + + D + SG G + + GA P V TR + R Sbjct: 62 ITRYGEVFLRHAGAALTALRQGLDSVSQERSGEGPPIRV----GALPTVSTRIMPR---- 113 Query: 123 QPEVSIEISEDTSAR-------QLLLLDQ---GRIDLMIGRSSVSSQPNLYHYEMLRGEP 172 +++ + E T AR +LL+Q G +DL++GR + + + +E L E Sbjct: 114 --AIALFLKEKTGARIKIVTGENAVLLEQLRIGDLDLVVGRLAAPDKMTGFSFEHLYSEQ 171 Query: 173 MCIVSGIDHPLATAQKVRLQELAEASWILYSSNMPMRIWIEHEFKLEGVKVPGNVIETAS 232 + HPL + ++ L++ ++ + +R ++EH G+ N IET S Sbjct: 172 VVFAVRAGHPLISGRQSLFAHLSDYPVLMPTRASIIRPFVEHFLIANGIAGLPNQIETVS 231 Query: 233 PFVTITLLAQSNMVAVMPLDIAHFFAAKQMLGILPVNLKTRIEHYGIVTRKNTTLSSLAK 292 + S+ + ++ + A +L LPV+ G+ R + S Sbjct: 232 DSFGRAFVRSSDAIWIISAGVVATDIADGVLAALPVDTSETRGPVGLTMRTDAIPSLPLS 291 Query: 293 MFIQILRQ 300 + +Q LR+ Sbjct: 292 ILMQTLRE 299 >RSc1440 [K] COG0583 Transcriptional regulator Rso Ralstonia solanacearum Length = 319 Score = 97.8 bits (242), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 80/302 (26%), Positives = 135/302 (44%), Gaps = 3/302 (0%) Query: 3 SIVSRLRFRQVALLTALDEQGSLHKAAEVMHMTQPAATKALHEMEDALGVTLFDRSPRGI 62 ++ SR+RFR ++ A+ ++ +L +AAE +H++QPA +K L E+E G L +R G Sbjct: 10 ALQSRIRFRHLSCFVAIAQERNLRRAAERLHLSQPAVSKTLCELEALSGAQLVERGRHGA 69 Query: 63 EATELGRCVIRYARLIQSDVANLRDELQNMISGRGGRLAIGTIMG-AAPFVTRALSRLRE 121 T G +RYA + L + L IG + A+ + A+++L Sbjct: 70 RLTAAGEHFLRYAVGATQALDAAAAALGSTGEPTPPVLEIGALPTVASGLLPEAIAQLHA 129 Query: 122 IQPEVSIEISEDTSARQLLLLDQGRIDLMIGRSSVSSQPNLYHYEMLRGEPMCIVSGIDH 181 ++P + + T+A L L G +DL++GR + + +E+L EP+ +V DH Sbjct: 130 LRPHAGVRLRTGTNADLLAALKAGELDLVVGRMAEPAMMQGLSFELLYAEPLALVVRPDH 189 Query: 182 PL--ATAQKVRLQELAEASWILYSSNMPMRIWIEHEFKLEGVKVPGNVIETASPFVTITL 239 PL L + + ++ R E F+ G+++P V ET S V L Sbjct: 190 PLMAEPGASASLPAVLDYPLVISPPGTVPRHHTEALFQTHGLRLPPGVTETLSVSVARLL 249 Query: 240 LAQSNMVAVMPLDIAHFFAAKQMLGILPVNLKTRIEHYGIVTRKNTTLSSLAKMFIQILR 299 +S+ V + P A L L + E G++ R T LA F+ +L Sbjct: 250 ACRSDAVWITPERAARDDMEHGWLVRLDLPTSATKEPVGLLRRSADTPGELATAFMTVLA 309 Query: 300 QQ 301 Q Sbjct: 310 SQ 311