BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0025.0027.p (1256 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc3034 [K] COG0085 DNA-directed RNA polymerase, beta subunit/14... 2123 0.0 NMB0132 [K] COG0085 DNA-directed RNA polymerase, beta subunit/14... 1871 0.0 NMA0142 [K] COG0085 DNA-directed RNA polymerase, beta subunit/14... 1871 0.0 PA4270 [K] COG0085 DNA-directed RNA polymerase, beta subunit/140... 1687 0.0 XF2633 [K] COG0085 DNA-directed RNA polymerase, beta subunit/140... 1633 0.0 YPO3747 [K] COG0085 DNA-directed RNA polymerase, beta subunit/14... 1624 0.0 rpoB [K] COG0085 DNA-directed RNA polymerase, beta subunit/140 k... 1621 0.0 ECs4910 [K] COG0085 DNA-directed RNA polymerase, beta subunit/14... 1621 0.0 STM4153 [K] COG0085 DNA-directed RNA polymerase, beta subunit/14... 1621 0.0 ZrpoB [K] COG0085 DNA-directed RNA polymerase, beta subunit/140 ... 1619 0.0 >RSc3034 [K] COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit Rso Ralstonia solanacearum Length = 1368 Score = 2123 bits (5502), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1023/1197 (85%), Positives = 1109/1197 (92%), Gaps = 2/1197 (0%) Query: 61 GKLLFSARIIPYRGSWLDFEFDPKDILFFRVDRRRKMPVTILLKAIGMTSEQILANFFVF 120 GKLLFSARIIPYRGSWLDFEFDPKDIL+FRVDRRRKMPVTILLK+IG+T EQILA+FFVF Sbjct: 171 GKLLFSARIIPYRGSWLDFEFDPKDILYFRVDRRRKMPVTILLKSIGLTPEQILAHFFVF 230 Query: 121 DNFNLHAEGADMEFVSERLRGEVARFDITDKSGKVMVAKDKRINAKHVRDIEAAGIKHIS 180 DNF L ++GA MEFV ERLRGEVARFDI+DK+GKV+V KDKRINAKH+RD++AAG K IS Sbjct: 231 DNFTLKSDGALMEFVPERLRGEVARFDISDKNGKVVVEKDKRINAKHIRDLDAAGTKLIS 290 Query: 181 VPEDYLLGRVLAKNIVDPETGEVVASANDELTEELLAKLREANISAIQTLYTNDLDQGGY 240 VPEDYLLGRVLAKNIVDP+TGEV+A+ANDELTE +L KLR+A + IQTLYTNDLDQG Y Sbjct: 291 VPEDYLLGRVLAKNIVDPDTGEVLANANDELTEGVLEKLRDAGVKEIQTLYTNDLDQGPY 350 Query: 241 ISQTLRTDDTADQTAARVAIYRMMRPGEPPTEESVEALFNGLFYSEDRYDLSAVGRMKFN 300 +SQTLRTDDT DQTAAR+AIYRMMRPGEPPTE++VEALF LFYSED YDLS VGRMK N Sbjct: 351 MSQTLRTDDTVDQTAARIAIYRMMRPGEPPTEDAVEALFQRLFYSEDSYDLSRVGRMKVN 410 Query: 301 RRVGRDELTGTMTLSNDDILAVIKILVELRNGRGEVDDIDHLGNRRVRCVGELAENQFRA 360 R+ R E TG M L++DDIL IK+LV LRNG+GEVDDIDHLGNRRVRCVGELAENQFRA Sbjct: 411 SRLNRSEGTGPMVLTDDDILDTIKLLVNLRNGKGEVDDIDHLGNRRVRCVGELAENQFRA 470 Query: 361 GLVRVERAVKERLGQAEADNLMPHDLINSKPISAAIREFFGSSQLSQFMDQTNPLSEITH 420 GL RVERAVKERLGQAE +NLMPHDLINSKPIS+AIREFFGSSQLSQFMDQTNPLSE+TH Sbjct: 471 GLSRVERAVKERLGQAETENLMPHDLINSKPISSAIREFFGSSQLSQFMDQTNPLSEVTH 530 Query: 421 KRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLALYARLNEYGF 480 KRR+SALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLALYA+LN+YGF Sbjct: 531 KRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLALYAQLNDYGF 590 Query: 481 LETPYRKVEGSKVTNQIDYLSAIEEGRYVIAQANATIDGEGKLSDELVSAREAGE--TIL 538 LETPYRKVE SK+T+Q+DYLSAIEEG+YV+AQANAT+D +G L DELVSARE E T + Sbjct: 591 LETPYRKVENSKLTDQVDYLSAIEEGKYVVAQANATVDKDGNLVDELVSAREGSERETRM 650 Query: 539 VSPERVQYMDVAPGQVVSVAASLIPFLEHDDANRALMGANMQRQAVPCLRPEKPLVGTGI 598 V+P+RVQY+DVAP Q+VS AASL+PFLEHDDANRALMGANMQRQAVPCLR +KPLVGTG+ Sbjct: 651 VTPDRVQYIDVAPSQIVSAAASLVPFLEHDDANRALMGANMQRQAVPCLRADKPLVGTGV 710 Query: 599 ERTVAVDSGTTVQALRGGVVDYVDAGRVVIRVNDDEAQAGEVGVDIYNLIKYTRSNQNTN 658 ERTVAVDSGT VQA RGG+VDYVDA RVVIRVNDDEA AGEVGVDIYNLIKYTRSNQNTN Sbjct: 711 ERTVAVDSGTAVQATRGGLVDYVDANRVVIRVNDDEAVAGEVGVDIYNLIKYTRSNQNTN 770 Query: 659 INQRPIVKIGDRVAKHDVIADGASTDMGELALGQNMLVAFMPWNGYNFEDSILISEKVVA 718 INQRP+VK+GD VA+ DVIADGASTD+GELALGQNMLVAFMPWNGYNFEDSILISE+VVA Sbjct: 771 INQRPMVKVGDIVARGDVIADGASTDLGELALGQNMLVAFMPWNGYNFEDSILISERVVA 830 Query: 719 DDRYTSIHIEELSVVARDTKLGAEEITRDISNLAENQLARLDESGIVYIGAEVEAGDTLV 778 +DRYTSIHIEELSVVARDTKLG EEITRDISNLAE QLARLDESGI YIGAEVEAGD +V Sbjct: 831 EDRYTSIHIEELSVVARDTKLGPEEITRDISNLAEAQLARLDESGITYIGAEVEAGDVMV 890 Query: 779 GKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPSGMVGTVIDVQVFTREGIQRDKR 838 GKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPSGM GTVIDVQVFTREG+ RDKR Sbjct: 891 GKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPSGMSGTVIDVQVFTREGVTRDKR 950 Query: 839 AQQIIDDELKRYRLDLNDQLRIVEGDAFQRLERLLIGKVANGGPKKLVKGTKLDKAYLDD 898 AQ IID+ELKRYRLDLNDQLRIVEGDAFQRLERLL+GKV NGGPKKL KGT L K YL D Sbjct: 951 AQSIIDEELKRYRLDLNDQLRIVEGDAFQRLERLLVGKVVNGGPKKLAKGTALTKEYLAD 1010 Query: 899 LDKFHWFDIRPADDDIANALEAIKESIAEKRHQFDLAFEEKRKKLTQGDELPPGVQKMVK 958 LDK+HWFDIRP+DDD+A LEA+KE+I +KRH FDLAFEEKRKKLTQGDELPPGV KMVK Sbjct: 1011 LDKWHWFDIRPSDDDVATQLEAVKEAIEQKRHDFDLAFEEKRKKLTQGDELPPGVIKMVK 1070 Query: 959 VYLAVKRRLQPGDKMAGRHGNKGVVSRILPIEDMPHMADGTPADIVLNPLGVPSRMNVGQ 1018 VYLAVKRRLQPGDKMAGRHGNKGVVS+I PIEDMP+MADGTPADIVLNPLGVPSRMNVGQ Sbjct: 1071 VYLAVKRRLQPGDKMAGRHGNKGVVSKITPIEDMPYMADGTPADIVLNPLGVPSRMNVGQ 1130 Query: 1019 VLEVHLGWAAKGLGLRLGEMVQAQAKVAELRKFLTTIYNESGKQEELDSFTDEEIIELVE 1078 +LE HLGWAA+GLG R+G M++AQAK AE+RK L IYNESGK E+LDS +D E++EL E Sbjct: 1131 ILETHLGWAARGLGERIGNMLKAQAKAAEMRKLLGQIYNESGKVEDLDSLSDAEVLELAE 1190 Query: 1079 NLKKGVPFATPVFDGAHEEETRRMLDLAYPDPIAKQLGMTPSKNQVTMYDGRTGEAFERT 1138 NLKKGVPFATPVFDGAHE+E RRMLDLAYP+ IAK+ G+T SK QVT++DGRTGEAFER Sbjct: 1191 NLKKGVPFATPVFDGAHEDEIRRMLDLAYPEDIAKEKGLTASKQQVTLFDGRTGEAFERP 1250 Query: 1139 VTVGYMHYLKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAS 1198 VT+G MH LKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAS Sbjct: 1251 VTLGVMHMLKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAS 1310 Query: 1199 YVLQEMLTVKSDDVNGRTKVYENLVKGDHVIDAGMPESFNVLVKEIRSLGIDIDLER 1255 YVLQEMLTVKSDDVNGRTKVYEN+VKG+H IDAGMPESFNVLVKEIRSLGIDIDLER Sbjct: 1311 YVLQEMLTVKSDDVNGRTKVYENIVKGEHSIDAGMPESFNVLVKEIRSLGIDIDLER 1367 Score = 100 bits (250), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 47/60 (78%), Positives = 55/60 (91%) Query: 1 MPVTILLKAIGMTSEQILANFFVFDNFNLHAEGADMEFVSERLRGEVARFDITDKSGKVM 60 MPVTILLK+IG+T EQILA+FFVFDNF L ++GA MEFV ERLRGEVARFDI+DK+GKV+ Sbjct: 207 MPVTILLKSIGLTPEQILAHFFVFDNFTLKSDGALMEFVPERLRGEVARFDISDKNGKVV 266 >NMB0132 [K] COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit Nme Neisseria meningitidis MC58 Length = 1394 Score = 1871 bits (4847), Expect = 0.0, Method: Compositional matrix adjust. Identities = 913/1220 (74%), Positives = 1033/1220 (84%), Gaps = 25/1220 (2%) Query: 61 GKLLFSARIIPYRGSWLDFEFDPKDILFFRVDRRRKMPVTILLKAIGMTSEQILANFFVF 120 GKLLFSARIIPYRGSWLDFEFDPKD+L+FR+DRRRKMPVTILLKA+G +EQIL F+ Sbjct: 174 GKLLFSARIIPYRGSWLDFEFDPKDLLYFRIDRRRKMPVTILLKALGYNNEQILDIFYDK 233 Query: 121 DNFNLHAEGADMEFVSERLRGEVARFDITDKSGKVMVAKDKRINAKHVRDIEAAGIKHIS 180 + F L + G + V++RL+GE A+ DI DK G V+VAK KRI AK++RDI AG+ + Sbjct: 234 ETFYLSSNGVQTDLVADRLKGETAKVDILDKEGNVLVAKGKRITAKNIRDITNAGLTRLD 293 Query: 181 VPEDYLLGRVLAKNIVDPETGEVVASANDELTEELLAKLREANISAIQTLYTNDLDQGGY 240 V + LLG+ LA +++D ETGEV+ASANDE+TEELLAK + I TLY N+LDQG Y Sbjct: 294 VEPESLLGKALAADLIDSETGEVLASANDEITEELLAKFDINGVKEITTLYINELDQGAY 353 Query: 241 ISQTLRTDDTADQTAARVAIYRMMRPGEPPTEESVEALFNGLFYSEDRYDLSAVGRMKFN 300 IS TLRTD+TA + AARVAIYRMMRPGEPPTEE+VE LFN LF+SED YDLS VGRMKFN Sbjct: 354 ISNTLRTDETAGRQAARVAIYRMMRPGEPPTEEAVEQLFNRLFFSEDSYDLSRVGRMKFN 413 Query: 301 RRVGRDELT----------------------GTMTLSNDDILAVIKILVELRNGRGEVDD 338 R +L+ G LS +DI+A I LVELRNG GEVDD Sbjct: 414 TRTYEQKLSEAQQNSWYGRLLNETFAGAADKGGYVLSVEDIVASIATLVELRNGHGEVDD 473 Query: 339 IDHLGNRRVRCVGELAENQFRAGLVRVERAVKERLGQAEADNLMPHDLINSKPISAAIRE 398 IDHLGNRRVR VGEL ENQFR+GL RVERAVKERL QAE++NLMPHDLIN+KP+SAAI+E Sbjct: 474 IDHLGNRRVRSVGELTENQFRSGLARVERAVKERLNQAESENLMPHDLINAKPVSAAIKE 533 Query: 399 FFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETP 458 FFGSSQLSQFMDQTNPLSE+THKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETP Sbjct: 534 FFGSSQLSQFMDQTNPLSEVTHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETP 593 Query: 459 EGPNIGLINSLALYARLNEYGFLETPYRKVEGSKVTNQIDYLSAIEEGRYVIAQANATID 518 EGPNIGLINSL++YAR N+YGFLETPYR+V KVT +IDYLSAIEEGRYVIAQANA +D Sbjct: 594 EGPNIGLINSLSVYARTNDYGFLETPYRRVIDGKVTEEIDYLSAIEEGRYVIAQANADLD 653 Query: 519 GEGKLSDELVSAREAGETILVSPERVQYMDVAPGQVVSVAASLIPFLEHDDANRALMGAN 578 +G L +LV+ RE GETI+ +P+RVQYMDVA GQVVSVAASLIPFLEHDDANRALMGAN Sbjct: 654 SDGNLIGDLVTCREKGETIMATPDRVQYMDVATGQVVSVAASLIPFLEHDDANRALMGAN 713 Query: 579 MQRQAVPCLRPEKPLVGTGIERTVAVDSGTTVQALRGGVVDYVDAGRVVIRVNDDEAQAG 638 MQRQAVPCLRPEKP+VGTGIER+VAVDS T + A RGGVV+YVDA RVVIRV+DDEA AG Sbjct: 714 MQRQAVPCLRPEKPMVGTGIERSVAVDSATAIVARRGGVVEYVDANRVVIRVHDDEATAG 773 Query: 639 EVGVDIYNLIKYTRSNQNTNINQRPIVKIGDRVAKHDVIADGASTDMGELALGQNMLVAF 698 EVGVDIYNL+K+TRSNQ+TNINQRP VK GD + + D++ADGASTD GELALGQNM +AF Sbjct: 774 EVGVDIYNLVKFTRSNQSTNINQRPAVKAGDVLQRGDLVADGASTDFGELALGQNMTIAF 833 Query: 699 MPWNGYNFEDSILISEKVVADDRYTSIHIEELSVVARDTKLGAEEITRDISNLAENQLAR 758 MPWNGYN+EDSILISEKV ADDRYTSIHIEEL+VVARDTKLGAE+ITRDI NL+E R Sbjct: 834 MPWNGYNYEDSILISEKVAADDRYTSIHIEELNVVARDTKLGAEDITRDIPNLSERMQNR 893 Query: 759 LDESGIVYIGAEVEAGDTLVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPSGM 818 LDESGIVYIGAEVEAGD LVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLR+P+GM Sbjct: 894 LDESGIVYIGAEVEAGDVLVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRMPTGM 953 Query: 819 VGTVIDVQVFTREGIQRDKRAQQIIDDELKRYRLDLNDQLRIVEGDAFQRLERLLIGKVA 878 GTVIDVQVFTREGIQRDKRAQ IID ELKRYRLDLNDQLRI + DAF R+ER+++G+ A Sbjct: 954 SGTVIDVQVFTREGIQRDKRAQSIIDSELKRYRLDLNDQLRIFDNDAFDRIERMIVGQKA 1013 Query: 879 NGGPKKLVKGTKLDKAYLDDLDKFH-WFDIRPADDDIANALEAIKESIAEKRHQFDLAFE 937 NGGP KL KG+++ YL L H WFDIR D+D+A LE IK S+ +KR + D +E Sbjct: 1014 NGGPMKLAKGSEITTEYLAGLPSRHDWFDIRLTDEDLAKQLELIKVSLQQKREEADELYE 1073 Query: 938 EKRKKLTQGDELPPGVQKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSRILPIEDMPHMAD 997 K+KKLTQGDEL PGVQKMVKV++A+KRRLQ GDKMAGRHGNKGVVSRILP+EDMP+MAD Sbjct: 1074 IKKKKLTQGDELQPGVQKMVKVFIAIKRRLQAGDKMAGRHGNKGVVSRILPVEDMPYMAD 1133 Query: 998 GTPADIVLNPLGVPSRMNVGQVLEVHLGWAAKGLGLRLGEMVQAQAKVAELRKFLTTIYN 1057 G P DIVLNPLGVPSRMN+GQ+LEVHLGWAAKG+G R+ M++ Q K ELR+FL +YN Sbjct: 1134 GRPVDIVLNPLGVPSRMNIGQILEVHLGWAAKGIGERIDRMLKEQRKAGELREFLNRLYN 1193 Query: 1058 ESGKQEELDSFTDEEIIELVENLKKGVPFATPVFDGAHEEETRRMLDLAYP--DPIAKQL 1115 SGK+E+LD+ TDEEIIEL NL+KG FA+PVFDGA E E R ML+LAYP DP ++L Sbjct: 1194 GSGKKEDLDALTDEEIIELASNLRKGASFASPVFDGAKESEIREMLNLAYPSDDPEVEKL 1253 Query: 1116 GMTPSKNQVTMYDGRTGEAFERTVTVGYMHYLKLHHLVDDKMHARSTGPYSLVTQQPLGG 1175 G SK Q+T+YDGR+GEAF+R VTVG MHYLKLHHLVD+KMHARSTGPYSLVTQQPLGG Sbjct: 1254 GFNDSKTQITLYDGRSGEAFDRKVTVGVMHYLKLHHLVDEKMHARSTGPYSLVTQQPLGG 1313 Query: 1176 KAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVNGRTKVYENLVKGDHVIDAGMPE 1235 KAQFGGQRFGEMEVWALEAYGA+Y LQEMLTVKSDDVNGRTK+YEN+VKG+H IDAGMPE Sbjct: 1314 KAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYENIVKGEHKIDAGMPE 1373 Query: 1236 SFNVLVKEIRSLGIDIDLER 1255 SFNVLVKEIRSLG+DIDLER Sbjct: 1374 SFNVLVKEIRSLGLDIDLER 1393 Score = 63.2 bits (152), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 30/60 (50%), Positives = 41/60 (68%) Query: 1 MPVTILLKAIGMTSEQILANFFVFDNFNLHAEGADMEFVSERLRGEVARFDITDKSGKVM 60 MPVTILLKA+G +EQIL F+ + F L + G + V++RL+GE A+ DI DK G V+ Sbjct: 210 MPVTILLKALGYNNEQILDIFYDKETFYLSSNGVQTDLVADRLKGETAKVDILDKEGNVL 269 >NMA0142 [K] COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit NmA Neisseria meningitidis Z2491 Length = 1392 Score = 1871 bits (4846), Expect = 0.0, Method: Compositional matrix adjust. Identities = 912/1220 (74%), Positives = 1033/1220 (84%), Gaps = 25/1220 (2%) Query: 61 GKLLFSARIIPYRGSWLDFEFDPKDILFFRVDRRRKMPVTILLKAIGMTSEQILANFFVF 120 GKLLFSARIIPYRGSWLDFEFDPKD+L+FR+DRRRKMPVTILLKA+G +EQIL F+ Sbjct: 172 GKLLFSARIIPYRGSWLDFEFDPKDLLYFRIDRRRKMPVTILLKALGYNNEQILDIFYDK 231 Query: 121 DNFNLHAEGADMEFVSERLRGEVARFDITDKSGKVMVAKDKRINAKHVRDIEAAGIKHIS 180 + F L + G + V+ RL+GE A+ DI DK G V+VAK KRI AK++RDI AG+ + Sbjct: 232 ETFYLSSNGVQTDLVAGRLKGETAKVDILDKEGNVLVAKGKRITAKNIRDITNAGLTRLD 291 Query: 181 VPEDYLLGRVLAKNIVDPETGEVVASANDELTEELLAKLREANISAIQTLYTNDLDQGGY 240 V + LLG+ LA +++D ETGEV+ASANDE+TEELLAK + I TLY N+LDQG Y Sbjct: 292 VEPESLLGKALAADLIDSETGEVLASANDEITEELLAKFDINGVKEITTLYINELDQGAY 351 Query: 241 ISQTLRTDDTADQTAARVAIYRMMRPGEPPTEESVEALFNGLFYSEDRYDLSAVGRMKFN 300 IS TLRTD+TA + AARVAIYRMMRPGEPPTEE+VE LFN LF+SED YDLS VGRMKFN Sbjct: 352 ISNTLRTDETAGRQAARVAIYRMMRPGEPPTEEAVEQLFNRLFFSEDSYDLSRVGRMKFN 411 Query: 301 RRVGRDELT----------------------GTMTLSNDDILAVIKILVELRNGRGEVDD 338 R +L+ G LS +DI+A I LVELRNG GEVDD Sbjct: 412 TRTYEQKLSEAQQNSWYGRLLNETFAGAADKGGYVLSVEDIVASIATLVELRNGHGEVDD 471 Query: 339 IDHLGNRRVRCVGELAENQFRAGLVRVERAVKERLGQAEADNLMPHDLINSKPISAAIRE 398 IDHLGNRRVR VGEL ENQFR+GL RVERAVKERL QAE++NLMPHDLIN+KP+SAAI+E Sbjct: 472 IDHLGNRRVRSVGELTENQFRSGLARVERAVKERLNQAESENLMPHDLINAKPVSAAIKE 531 Query: 399 FFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETP 458 FFGSSQLSQFMDQTNPLSE+THKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETP Sbjct: 532 FFGSSQLSQFMDQTNPLSEVTHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETP 591 Query: 459 EGPNIGLINSLALYARLNEYGFLETPYRKVEGSKVTNQIDYLSAIEEGRYVIAQANATID 518 EGPNIGLINSL++YAR N+YGFLETPYR+V KVT +IDYLSAIEEGRYVIAQANA +D Sbjct: 592 EGPNIGLINSLSVYARTNDYGFLETPYRRVIDGKVTEEIDYLSAIEEGRYVIAQANADLD 651 Query: 519 GEGKLSDELVSAREAGETILVSPERVQYMDVAPGQVVSVAASLIPFLEHDDANRALMGAN 578 +G L +LV+ RE GETI+ +P+RVQYMDVA GQVVSVAASLIPFLEHDDANRALMGAN Sbjct: 652 SDGNLIGDLVTCREKGETIMATPDRVQYMDVATGQVVSVAASLIPFLEHDDANRALMGAN 711 Query: 579 MQRQAVPCLRPEKPLVGTGIERTVAVDSGTTVQALRGGVVDYVDAGRVVIRVNDDEAQAG 638 MQRQAVPCLRPEKP+VGTGIER+VAVDS T + A RGGVV+YVDA RVV+RV+DDEA AG Sbjct: 712 MQRQAVPCLRPEKPMVGTGIERSVAVDSATAIVARRGGVVEYVDANRVVVRVHDDEATAG 771 Query: 639 EVGVDIYNLIKYTRSNQNTNINQRPIVKIGDRVAKHDVIADGASTDMGELALGQNMLVAF 698 EVGVDIYNL+K+TRSNQ+TNINQRP VK GD + + D++ADGASTD+GELALGQNM +AF Sbjct: 772 EVGVDIYNLVKFTRSNQSTNINQRPAVKAGDVLQRGDLVADGASTDLGELALGQNMTIAF 831 Query: 699 MPWNGYNFEDSILISEKVVADDRYTSIHIEELSVVARDTKLGAEEITRDISNLAENQLAR 758 MPWNGYN+EDSILISEKV ADDRYTSIHIEEL+VVARDTKLGAE+ITRDI NL+E R Sbjct: 832 MPWNGYNYEDSILISEKVAADDRYTSIHIEELNVVARDTKLGAEDITRDIPNLSERMQNR 891 Query: 759 LDESGIVYIGAEVEAGDTLVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPSGM 818 LDESGIVYIGAEVEAGD LVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLR+P+GM Sbjct: 892 LDESGIVYIGAEVEAGDVLVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRMPTGM 951 Query: 819 VGTVIDVQVFTREGIQRDKRAQQIIDDELKRYRLDLNDQLRIVEGDAFQRLERLLIGKVA 878 GTVIDVQVFTREGIQRDKRAQ IID ELKRYRLDLNDQLRI + DAF R+ER+++G+ A Sbjct: 952 SGTVIDVQVFTREGIQRDKRAQSIIDSELKRYRLDLNDQLRIFDNDAFDRIERMIVGQKA 1011 Query: 879 NGGPKKLVKGTKLDKAYLDDLDKFH-WFDIRPADDDIANALEAIKESIAEKRHQFDLAFE 937 NGGP KL KG+++ YL L H WFDIR D+D+A LE IK S+ +KR + D +E Sbjct: 1012 NGGPMKLAKGSEITTEYLAGLPSRHDWFDIRLTDEDLAKQLELIKVSLQQKREEADELYE 1071 Query: 938 EKRKKLTQGDELPPGVQKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSRILPIEDMPHMAD 997 K+KKLTQGDEL PGVQKMVKV++A+KRRLQ GDKMAGRHGNKGVVSRILP+EDMP+MAD Sbjct: 1072 IKKKKLTQGDELQPGVQKMVKVFIAIKRRLQAGDKMAGRHGNKGVVSRILPVEDMPYMAD 1131 Query: 998 GTPADIVLNPLGVPSRMNVGQVLEVHLGWAAKGLGLRLGEMVQAQAKVAELRKFLTTIYN 1057 G P DIVLNPLGVPSRMN+GQ+LEVHLGWAAKG+G R+ M++ Q K ELR+FL +YN Sbjct: 1132 GRPVDIVLNPLGVPSRMNIGQILEVHLGWAAKGIGERIDRMLKEQRKAGELREFLNRLYN 1191 Query: 1058 ESGKQEELDSFTDEEIIELVENLKKGVPFATPVFDGAHEEETRRMLDLAYP--DPIAKQL 1115 SGK+E+LD+ TDEEIIEL NL+KG FA+PVFDGA E E R ML+LAYP DP ++L Sbjct: 1192 GSGKKEDLDALTDEEIIELASNLRKGASFASPVFDGAKESEIREMLNLAYPSDDPEVEKL 1251 Query: 1116 GMTPSKNQVTMYDGRTGEAFERTVTVGYMHYLKLHHLVDDKMHARSTGPYSLVTQQPLGG 1175 G SK Q+T+YDGR+GEAF+R VTVG MHYLKLHHLVD+KMHARSTGPYSLVTQQPLGG Sbjct: 1252 GFNDSKTQITLYDGRSGEAFDRKVTVGVMHYLKLHHLVDEKMHARSTGPYSLVTQQPLGG 1311 Query: 1176 KAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVNGRTKVYENLVKGDHVIDAGMPE 1235 KAQFGGQRFGEMEVWALEAYGA+Y LQEMLTVKSDDVNGRTK+YEN+VKG+H IDAGMPE Sbjct: 1312 KAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYENIVKGEHKIDAGMPE 1371 Query: 1236 SFNVLVKEIRSLGIDIDLER 1255 SFNVLVKEIRSLG+DIDLER Sbjct: 1372 SFNVLVKEIRSLGLDIDLER 1391 >PA4270 [K] COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit Pae Pseudomonas aeruginosa Length = 1357 Score = 1687 bits (4370), Expect = 0.0, Method: Compositional matrix adjust. Identities = 827/1233 (67%), Positives = 983/1233 (79%), Gaps = 12/1233 (0%) Query: 25 DNFNLHAEGADMEFVSERLRGEVARFDITDKSGKVMGKLLFSARIIPYRGSWLDFEFDPK 84 +N G + VS+ R FD GKLL+SARIIPYRGSWLDFEFDPK Sbjct: 136 ENGTFIINGTERVIVSQLHRSPGVFFDHDRGKTHSSGKLLYSARIIPYRGSWLDFEFDPK 195 Query: 85 DILFFRVDRRRKMPVTILLKAIGMTSEQILANFFVFDNFNLHAEGADMEFVSERLRGEVA 144 D +F R+DRRRK+P ++LL+A+G ++E+IL F+ + F++ E ++E V +RLRGEVA Sbjct: 196 DCVFVRIDRRRKLPASVLLRALGYSTEEILNAFYATNVFHIKGETLNLELVPQRLRGEVA 255 Query: 145 RFDITDKSGKVMVAKDKRINAKHVRDIEAAGIKHISVPEDYLLGRVLAKNIVDPETGEVV 204 DI D SGKV+V + +RI A+H+ +E AG+ + VP DYL+GR +AK IV P TGE++ Sbjct: 256 SIDIKDGSGKVIVEQGRRITARHINQLEKAGVSQLEVPFDYLIGRTIAKAIVHPATGEII 315 Query: 205 ASANDELTEELLAKLREANISAIQTLYTNDLDQGGYISQTLRTDDTADQTAARVAIYRMM 264 A N ELT +LLAK+ +A + I+TLYTND+D G +IS TL+ D+T++Q A V IYRMM Sbjct: 316 AECNTELTLDLLAKVAKAQVVRIETLYTNDIDCGPFISDTLKIDNTSNQLEALVEIYRMM 375 Query: 265 RPGEPPTEESVEALFNGLFYSEDRYDLSAVGRMKFNRRVGRDELTGTMTLSNDDILAVIK 324 RPGEPPT+E+ E LF LF+S +RYDLSAVGRMKFNRR+GR E+ G LS +DI+ V+K Sbjct: 376 RPGEPPTKEAAETLFGNLFFSAERYDLSAVGRMKFNRRIGRTEIEGPGVLSKEDIIDVLK 435 Query: 325 ILVELRNGRGEVDDIDHLGNRRVRCVGELAENQFRAGLVRVERAVKERLGQAEADNLMPH 384 LV++RNG+G VDDIDHLGNRRVRCVGE+AENQFR GLVRVERAVKERL AE++ LMP Sbjct: 436 TLVDIRNGKGIVDDIDHLGNRRVRCVGEMAENQFRVGLVRVERAVKERLSMAESEGLMPQ 495 Query: 385 DLINSKPISAAIREFFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDV 444 DLIN+KP++AAI+EFFGSSQLSQFMDQ NPLSEITHKRRVSALGPGGLTRERAGFEVRDV Sbjct: 496 DLINAKPVAAAIKEFFGSSQLSQFMDQNNPLSEITHKRRVSALGPGGLTRERAGFEVRDV 555 Query: 445 HPTHYGRVCPIETPEGPNIGLINSLALYARLNEYGFLETPYRKVEGSKVTNQIDYLSAIE 504 HPTHYGRVCPIETPEGPNIGLINSLA YAR N+YGFLE+PYR V+ S VT++I +LSAIE Sbjct: 556 HPTHYGRVCPIETPEGPNIGLINSLATYARTNKYGFLESPYRVVKDSLVTDEIVFLSAIE 615 Query: 505 EGRYVIAQANATIDGEGKLSDELVSAREAGETILVSPERVQYMDVAPGQVVSVAASLIPF 564 E +VIAQA+AT++ +G+L DELV+ R E + +PE V MDV+P QVVSVAASLIPF Sbjct: 616 EADHVIAQASATLNEKGQLVDELVAVRHLNEFTVKAPEDVTLMDVSPKQVVSVAASLIPF 675 Query: 565 LEHDDANRALMGANMQRQAVPCLRPEKPLVGTGIERTVAVDSGTTVQALRGGVVDYVDAG 624 LEHDDANRALMG+NMQRQAVP LR +KPLVGTG+ER VA DSG V A RGGV+D VDA Sbjct: 676 LEHDDANRALMGSNMQRQAVPTLRADKPLVGTGMERNVARDSGVCVVARRGGVIDSVDAS 735 Query: 625 RVVIRVNDDEAQAGEVGVDIYNLIKYTRSNQNTNINQRPIVKIGDRVAKHDVIADGASTD 684 RVV+RV DDE + GE GVDIYNL KYTRSNQNT INQRP+V GD VA+ D++ADG STD Sbjct: 736 RVVVRVADDEVETGEAGVDIYNLTKYTRSNQNTCINQRPLVSKGDVVARGDILADGPSTD 795 Query: 685 MGELALGQNMLVAFMPWNGYNFEDSILISEKVVADDRYTSIHIEELSVVARDTKLGAEEI 744 MGELALGQNM VAFMPWNG+NFEDSI +SE+VV +DR+T+IHI+EL+ VARDTKLG EEI Sbjct: 796 MGELALGQNMRVAFMPWNGFNFEDSICLSERVVQEDRFTTIHIQELTCVARDTKLGPEEI 855 Query: 745 TRDISNLAENQLARLDESGIVYIGAEVEAGDTLVGKVTPKGETQLTPEEKLLRAIFGEKA 804 T DI N+ E L +LDE+GIVY+GAEV+AGD LVGKVTPKGETQLTPEEKLLRAIFGEKA Sbjct: 856 TADIPNVGEAALNKLDEAGIVYVGAEVQAGDILVGKVTPKGETQLTPEEKLLRAIFGEKA 915 Query: 805 SDVKDTSLRVPSGMVGTVIDVQVFTREGIQRDKRAQQIIDDELKRYRLDLNDQLRIVEGD 864 SDVKDTSLRVP+G GTVIDVQVFTR+G++RD RA I +L + R DLN++ RIVEG Sbjct: 916 SDVKDTSLRVPTGTKGTVIDVQVFTRDGVERDSRALSIEKMQLDQIRKDLNEEFRIVEGA 975 Query: 865 AFQRLERLLIGKVANGGPKKLVKGTKLDKAYLDDLDKFHWFDIRPADDDIANALEAIKES 924 F+RL L+G A GGP L KGT++ YLD L++ WF +R ADD + LE + Sbjct: 976 TFERLRAALVGAKAEGGP-ALKKGTEITDDYLDGLERGQWFKLRMADDALNEQLEKAQAY 1034 Query: 925 IAEKRHQFDLAFEEKRKKLTQGDELPPGVQKMVKVYLAVKRRLQPGDKMAGRHGNKGVVS 984 I+++R D FE+K++KL QGD+L PGV K+VKVYLA+KRR+QPGDKMAGRHGNKGVVS Sbjct: 1035 ISDRRQLLDDKFEDKKRKLQQGDDLAPGVLKIVKVYLAIKRRIQPGDKMAGRHGNKGVVS 1094 Query: 985 RILPIEDMPHMADGTPADIVLNPLGVPSRMNVGQVLEVHLGWAAKGLGLRLGEMVQAQAK 1044 I+P+EDMPH A+GTP DIVLNPLGVPSRMNVGQ+LE HLG AAKGLG ++ M++ Q K Sbjct: 1095 VIMPVEDMPHDANGTPVDIVLNPLGVPSRMNVGQILETHLGLAAKGLGEKINRMLEEQRK 1154 Query: 1045 VAELRKFLTTIYNE-SGKQEELDSFTDEEIIELVENLKKGVPFATPVFDGAHEEETRRML 1103 VAELRKFL IYNE G++E LD D EI+ L +NL+ GVP ATPVFDGA E E + ML Sbjct: 1155 VAELRKFLHEIYNEIGGREENLDELGDNEILALAKNLRGGVPMATPVFDGAKEREIKAML 1214 Query: 1104 DLAYPDPIAKQLGMTPSKNQVTMYDGRTGEAFERTVTVGYMHYLKLHHLVDDKMHARSTG 1163 LA P Q+ ++DGRTG FER TVGYM+ LKL+HLVDDKMHARSTG Sbjct: 1215 KLAD----------LPESGQMRLFDGRTGNQFERPTTVGYMYMLKLNHLVDDKMHARSTG 1264 Query: 1164 PYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVNGRTKVYENLV 1223 YSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGA+Y LQEMLTVKSDDVNGRTK+Y+N+V Sbjct: 1265 SYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIV 1324 Query: 1224 KGDHVIDAGMPESFNVLVKEIRSLGIDIDLERE 1256 GDH ++AGMPESFNVL+KEIRSLGIDI+LE E Sbjct: 1325 DGDHRMEAGMPESFNVLIKEIRSLGIDIELETE 1357 >XF2633 [K] COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit Xfa Xylella fastidiosa 9a5c Length = 1388 Score = 1633 bits (4229), Expect = 0.0, Method: Compositional matrix adjust. Identities = 807/1258 (64%), Positives = 977/1258 (77%), Gaps = 40/1258 (3%) Query: 25 DNFNLHAEGADMEFVSERLRGEVARFDITDKSGKVMGKLLFSARIIPYRGSWLDFEFDPK 84 +N G + VS+ R FD GKLL+SARIIP RGSWLDFEFDPK Sbjct: 141 ENGTFIVNGTERVIVSQLHRSPGVFFDHDRGKTHSSGKLLYSARIIPCRGSWLDFEFDPK 200 Query: 85 DILFFRVDRRRKMPVTILLKAIGMTSEQILANFFVFDNFNLHAE-GADMEFVSERLRGEV 143 D LF R+DRRRK+PV+ILL+A+G ++E+IL FF + F+++ + G +E V ERLRGE+ Sbjct: 201 DALFTRIDRRRKLPVSILLRALGYSNEEILGEFFEINTFHINPDKGVQLELVPERLRGEI 260 Query: 144 ARFDITDKSGKVMVAKDKRINAKHVRDIEAAGIKHISVPEDYLLGRVLAKNIVDPETGEV 203 F++TD G V+V KRI A+HV+ +EA+GI ++VP++YL+GR+L+ +++D TGE+ Sbjct: 261 LSFNLTDGGG-VIVEAGKRITARHVKQLEASGISALAVPDEYLIGRILSHDVIDATTGEL 319 Query: 204 VASANDELTEELLAKLREANISAIQTLYTNDLDQGGYISQTLRTDDTADQTAARVAIYRM 263 +ASAN E+ E+ + R+A I ++ TL+ NDLD+G Y+S TLR D T Q A+V IYRM Sbjct: 320 LASANSEVNEDRIVAFRKAGIDSVGTLWVNDLDRGAYLSNTLRIDPTRTQLEAQVEIYRM 379 Query: 264 MRPGEPPTEESVEALFNGLFYSEDRYDLSAVGRMKFNRRVGRDELTGTMTL--------S 315 MRPGEPPT+E+ + LF+ LF++ DRYDLS VGRMKFNRRVGR E+ G L Sbjct: 380 MRPGEPPTKEAAQNLFHNLFFTFDRYDLSMVGRMKFNRRVGRKEVAGEPVLYDKKYFSDR 439 Query: 316 ND--------------DILAVIKILVELRNGRGEVDDIDHLGNRRVRCVGELAENQFRAG 361 ND DIL VIK L E+RNGRG VDDIDHLGNRRVR VGE+AEN FR G Sbjct: 440 NDEESRRLVSKLGETSDILDVIKGLCEIRNGRGVVDDIDHLGNRRVRSVGEMAENVFRVG 499 Query: 362 LVRVERAVKERLGQAEADNLMPHDLINSKPISAAIREFFGSSQLSQFMDQTNPLSEITHK 421 LVRVERAVKERL AE++ L P +LIN+KP++AAI+EFFGSSQLSQFMDQ NPLSE+THK Sbjct: 500 LVRVERAVKERLSMAESEGLTPQELINAKPVAAAIKEFFGSSQLSQFMDQNNPLSEVTHK 559 Query: 422 RRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLALYARLNEYGFL 481 RR+SALGPGGLTRERAGFEVRDVH +HYG +C IETPEGPNIGLINSLA++AR N+YGFL Sbjct: 560 RRLSALGPGGLTRERAGFEVRDVHLSHYGCLCTIETPEGPNIGLINSLAVFARTNQYGFL 619 Query: 482 ETPYRKVEGSKVTNQIDYLSAIEEGRYVIAQANATIDGEGKLSDELVSAREAGETILVSP 541 ETPYRKV +VT++++YLSAIEE +YVIAQAN D G+L++ V R GE++L P Sbjct: 620 ETPYRKVVEGRVTDEVEYLSAIEENQYVIAQANTLTDDNGQLTESFVPCRFQGESLLKPP 679 Query: 542 ERVQYMDVAPGQVVSVAASLIPFLEHDDANRALMGANMQRQAVPCLRPEKPLVGTGIERT 601 V YMDV+P Q VSVAA+L+PFLEHDDANRALMGANMQRQAVP LR +KPLVGTGIERT Sbjct: 680 SYVHYMDVSPMQTVSVAAALVPFLEHDDANRALMGANMQRQAVPTLRAQKPLVGTGIERT 739 Query: 602 VAVDSGTTVQALRGGVVDYVDAGRVVIRVNDDE-AQAGEVGVDIYNLIKYTRSNQNTNIN 660 VA DSG TV A RGGV+D VDAGR+V++VN+ E A + GVDIY LIKYTRSNQNT IN Sbjct: 740 VARDSGVTVNARRGGVIDQVDAGRIVVKVNESEIIGATDAGVDIYGLIKYTRSNQNTCIN 799 Query: 661 QRPIVKIGDRVAKHDVIADGASTDMGELALGQNMLVAFMPWNGYNFEDSILISEKVVADD 720 QRP+V +GD V DV+ADG STD+GELALGQNML+AFMPWNGYNFEDSIL+SE+VV +D Sbjct: 800 QRPLVNVGDIVTSGDVLADGPSTDIGELALGQNMLIAFMPWNGYNFEDSILLSERVVEED 859 Query: 721 RYTSIHIEELSVVARDTKLGAEEITRDISNLAENQLARLDESGIVYIGAEVEAGDTLVGK 780 RYT+IHIEEL+ +ARDTKLG+EEI+ DI N++E L RLDESG+VYIGAEV AGD LVGK Sbjct: 860 RYTTIHIEELTCIARDTKLGSEEISADIPNVSEQALNRLDESGVVYIGAEVRAGDILVGK 919 Query: 781 VTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPSGMVGTVIDVQVFTREGIQRDKRAQ 840 VTPKGE+QLTPEEKLLRAIFGEKASDVKD+SLRVP GM GTVIDVQVFTR+GI++DKRA Sbjct: 920 VTPKGESQLTPEEKLLRAIFGEKASDVKDSSLRVPPGMDGTVIDVQVFTRDGIEKDKRAH 979 Query: 841 QIIDDELKRYRLDLNDQLRIVEGDAFQRLERLLIGKVANGGPKKLVKGTKLDKAYLDDLD 900 QI + E+KR + D +DQ RI+EG + RL ++GKV N G + KG + AYLD L Sbjct: 980 QIEEYEIKRVKKDFDDQFRILEGAIYARLRSQIVGKVVNSG-VDIKKGEVITGAYLDGLK 1038 Query: 901 KFHWFDIRPADDDIANALEAIKESIAEKRHQFDLAFEEKRKKLTQGDELPPGVQKMVKVY 960 K WF +R D+ A++ ++ I + +FD F +KR K+TQGD+L PGV KMVKV+ Sbjct: 1039 KSDWFALRMKDEVAVEAIDRAQKQIQAYQKEFDQRFSDKRSKITQGDDLAPGVLKMVKVF 1098 Query: 961 LAVKRRLQPGDKMAGRHGNKGVVSRILPIEDMPHMADGTPADIVLNPLGVPSRMNVGQVL 1020 LAVKR +QPGDKMAGRHGNKGVVS ++P+EDMP M DGTP DIVLNPLGVPSRMN+GQ+L Sbjct: 1099 LAVKRCIQPGDKMAGRHGNKGVVSNVVPVEDMPFMEDGTPVDIVLNPLGVPSRMNIGQIL 1158 Query: 1021 EVHLGWAAKGLGLRLGEMVQAQAKVAELRKFLTTIYNES----GKQEELDSFTDEEIIEL 1076 EVHLGWAAKGLG R+ M++A A +A+LRKFL IYN G++ +L F+D+E++ + Sbjct: 1159 EVHLGWAAKGLGHRIQRMLEANAAIADLRKFLNEIYNHDKSVVGERVDLSQFSDDELLNM 1218 Query: 1077 VENLKKGVPFATPVFDGAHEEETRRMLDLAYPDPIAKQLGMTPSKNQVTMYDGRTGEAFE 1136 +NL GVP A+PVFDGA E+E +RMLDLA P+ Q +YDG TGE F+ Sbjct: 1219 AKNLTDGVPMASPVFDGASEQEIKRMLDLAE----------LPTGGQTQLYDGHTGEPFD 1268 Query: 1137 RTVTVGYMHYLKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYG 1196 R TVGYMHYLKL+HLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYG Sbjct: 1269 RKTTVGYMHYLKLNHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYG 1328 Query: 1197 ASYVLQEMLTVKSDDVNGRTKVYENLVKGDHVIDAGMPESFNVLVKEIRSLGIDIDLE 1254 A+Y LQEMLTVKSDDV GR ++Y+N+V GDH + AGMPESFNVLVKEIRSL I+I+LE Sbjct: 1329 AAYTLQEMLTVKSDDVQGRNQMYKNIVDGDHQMVAGMPESFNVLVKEIRSLAINIELE 1386 >YPO3747 [K] COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit Ype Yersinia pestis Length = 1342 Score = 1624 bits (4205), Expect = 0.0, Method: Compositional matrix adjust. Identities = 799/1235 (64%), Positives = 973/1235 (78%), Gaps = 27/1235 (2%) Query: 25 DNFNLHAEGADMEFVSERLRGEVARFDITDKSGKVMGKLLFSARIIPYRGSWLDFEFDPK 84 +N G + VS+ R FD GK+L++ARIIPYRGSWLDFEFDPK Sbjct: 132 ENGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPK 191 Query: 85 DILFFRVDRRRKMPVTILLKAIGMTSEQILANFFVFDNFNLHAEGADMEFVSERLRGEVA 144 D LF R+DRRRK+P TI+L+A+ T+ QIL FF F + ME V ERLRGE A Sbjct: 192 DNLFVRIDRRRKLPATIILRALNFTTAQILDLFFEKVVFEIRDNKLQMELVPERLRGETA 251 Query: 145 RFDITDKSGKVMVAKDKRINAKHVRDIEAAGIKHISVPEDYLLGRVLAKNIVDPETGEVV 204 FDI + +GKV V K +RI A+H+R +E GI I VP +Y+ G+V+AK+ VD TGE++ Sbjct: 252 SFDI-EANGKVYVEKARRITARHIRQLEKDGIDRIEVPVEYIAGKVVAKDYVDASTGELI 310 Query: 205 ASANDELTEELLAKLREANISAIQTLYTNDLDQGGYISQTLRTDDTADQTAARVAIYRMM 264 +AN EL+ +LLAKL +A I+TL+TNDLD G YIS+TLR D T+D+ +A V IYRMM Sbjct: 311 CAANMELSLDLLAKLSQAGHKQIETLFTNDLDHGAYISETLRVDPTSDRLSALVEIYRMM 370 Query: 265 RPGEPPTEESVEALFNGLFYSEDRYDLSAVGRMKFNRRVGRDELTGTMTLSNDDILAVIK 324 RPGEPPT E+ E LF LF+SEDRYDLSAVGRMKFNR + RDE+ G+ LS +DI V+K Sbjct: 371 RPGEPPTREAAENLFENLFFSEDRYDLSAVGRMKFNRSLLRDEIEGSGILSKEDITEVMK 430 Query: 325 ILVELRNGRGEVDDIDHLGNRRVRCVGELAENQFRAGLVRVERAVKERLGQAEADNLMPH 384 L+++RNGRGEVDDIDHLGNRR+R VGE+AENQFR GLVRVERAVKERL + D LMP Sbjct: 431 KLIDIRNGRGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQ 490 Query: 385 DLINSKPISAAIREFFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDV 444 D+IN+KPISAA++EFFGSSQLSQFMDQ NPLSEITHKRR+SALGPGGLTRERAGFEVRDV Sbjct: 491 DMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDV 550 Query: 445 HPTHYGRVCPIETPEGPNIGLINSLALYARLNEYGFLETPYRKVEGSKVTNQIDYLSAIE 504 HPTHYGRVCPIETPEGPNIGLINSL++YA+ NEYGFLETPYR+V VT++I+YLSAIE Sbjct: 551 HPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRRVRDGVVTDEINYLSAIE 610 Query: 505 EGRYVIAQANATIDGEGKLSDELVSAREAGETILVSPERVQYMDVAPGQVVSVAASLIPF 564 EG +VIAQAN+ +D EG+ ++LV+ R GE+ L S E+V YMDV+ Q+VSV ASLIPF Sbjct: 611 EGNFVIAQANSNLDDEGRFLEDLVTCRSKGESSLFSREQVDYMDVSTQQIVSVGASLIPF 670 Query: 565 LEHDDANRALMGANMQRQAVPCLRPEKPLVGTGIERTVAVDSGTTVQALRGGVVDYVDAG 624 LEHDDANRALMGANMQRQAVP LR +KPLVGTG+ER VAVDSG T A RGG V YVDA Sbjct: 671 LEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTSVAKRGGTVQYVDAS 730 Query: 625 RVVIRVNDDEAQAGEVGVDIYNLIKYTRSNQNTNINQRPIVKIGDRVAKHDVIADGASTD 684 R+VI+VN+DE GE G+DIYNL KYTRSNQNT INQ P V +G+ + + DV+ADG STD Sbjct: 731 RIVIKVNEDEMHPGEAGIDIYNLTKYTRSNQNTCINQMPCVNLGEPIERGDVLADGPSTD 790 Query: 685 MGELALGQNMLVAFMPWNGYNFEDSILISEKVVADDRYTSIHIEELSVVARDTKLGAEEI 744 +GELALGQNM VAFMPWNGYNFEDSIL+SE+VV +DR+T+IHI+EL+ V+RDTKLG EEI Sbjct: 791 LGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEI 850 Query: 745 TRDISNLAENQLARLDESGIVYIGAEVEAGDTLVGKVTPKGETQLTPEEKLLRAIFGEKA 804 T DI N+ E L++LDESGIVYIGAEV GD LVGKVTPKGETQLTPEEKLLRAIFGEKA Sbjct: 851 TADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKA 910 Query: 805 SDVKDTSLRVPSGMVGTVIDVQVFTREGIQRDKRAQQIIDDELKRYRLDLNDQLRIVEGD 864 SDVKD+SLRVP+G+ GTVIDVQVFTR+G+++DKRA +I + +LK+ + DL ++L+I+E Sbjct: 911 SDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLTEELQILEAG 970 Query: 865 AFQRLERLLIGKVANGGPKKLVKGTKLDKAYLDDLDKFHWFDIRPADDDIANALEAIKES 924 F R+ +L+ +GG ++ KL K L + W ++ D+D N LE + E Sbjct: 971 LFARIHAVLV----SGG----IEAEKLSK-----LPRERWLELGLTDEDKQNQLEQLAEQ 1017 Query: 925 IAEKRHQFDLAFEEKRKKLTQGDELPPGVQKMVKVYLAVKRRLQPGDKMAGRHGNKGVVS 984 E + +F+ + KR+K+TQGD+L PGV K+VKVYLAVKR++QPGDKMAGRHGNKGV+S Sbjct: 1018 YDEMKSEFEKKMDAKRRKITQGDDLAPGVLKIVKVYLAVKRQIQPGDKMAGRHGNKGVIS 1077 Query: 985 RILPIEDMPHMADGTPADIVLNPLGVPSRMNVGQVLEVHLGWAAKGLGLRLGEMVQAQAK 1044 +I PIEDMP+ +GTP DIVLNPLGVPSRMN+GQ+LE HLG AAKG+G ++ M++ Q + Sbjct: 1078 KINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGEKINAMLKKQEE 1137 Query: 1045 VAELRKFLTTIY---NESGKQEELDSFTDEEIIELVENLKKGVPFATPVFDGAHEEETRR 1101 VA+LR+F+ Y + ++ +L +FTD+E++ L ENLKKG+P ATPVFDGA E+E + Sbjct: 1138 VAKLREFIQKAYDLGDNVCQKVDLSTFTDDEVLRLAENLKKGMPIATPVFDGATEKEIKE 1197 Query: 1102 MLDLAYPDPIAKQLGMTPSKNQVTMYDGRTGEAFERTVTVGYMHYLKLHHLVDDKMHARS 1161 +L QLG P+ Q+T++DGRTGE FER VTVGYM+ LKL+HLVDDKMHARS Sbjct: 1198 LL----------QLGGLPTSGQITLFDGRTGEQFERQVTVGYMYMLKLNHLVDDKMHARS 1247 Query: 1162 TGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVNGRTKVYEN 1221 TG YSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGA+Y LQEMLTVKSDDVNGRTK+Y+N Sbjct: 1248 TGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKN 1307 Query: 1222 LVKGDHVIDAGMPESFNVLVKEIRSLGIDIDLERE 1256 +V GDH ++ GMPESFNVL+KEIRSLGI+I+LE E Sbjct: 1308 IVDGDHRMEPGMPESFNVLLKEIRSLGINIELEEE 1342 >rpoB [K] COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit Eco Escherichia coli K12 Length = 1342 Score = 1621 bits (4198), Expect = 0.0, Method: Compositional matrix adjust. Identities = 802/1235 (64%), Positives = 975/1235 (78%), Gaps = 27/1235 (2%) Query: 25 DNFNLHAEGADMEFVSERLRGEVARFDITDKSGKVMGKLLFSARIIPYRGSWLDFEFDPK 84 DN G + VS+ R FD GK+L++ARIIPYRGSWLDFEFDPK Sbjct: 132 DNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPK 191 Query: 85 DILFFRVDRRRKMPVTILLKAIGMTSEQILANFFVFDNFNLHAEGADMEFVSERLRGEVA 144 D LF R+DRRRK+P TI+L+A+ T+EQIL FF F + ME V ERLRGE A Sbjct: 192 DNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQMELVPERLRGETA 251 Query: 145 RFDITDKSGKVMVAKDKRINAKHVRDIEAAGIKHISVPEDYLLGRVLAKNIVDPETGEVV 204 FDI + +GKV V K +RI A+H+R +E +K I VP +Y+ G+V+AK+ +D TGE++ Sbjct: 252 SFDI-EANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELI 310 Query: 205 ASANDELTEELLAKLREANISAIQTLYTNDLDQGGYISQTLRTDDTADQTAARVAIYRMM 264 +AN EL+ +LLAKL ++ I+TL+TNDLD G YIS+TLR D T D+ +A V IYRMM Sbjct: 311 CAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMM 370 Query: 265 RPGEPPTEESVEALFNGLFYSEDRYDLSAVGRMKFNRRVGRDELTGTMTLSNDDILAVIK 324 RPGEPPT E+ E+LF LF+SEDRYDLSAVGRMKFNR + R+E+ G+ LS DDI+ V+K Sbjct: 371 RPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLREEIEGSGILSKDDIIDVMK 430 Query: 325 ILVELRNGRGEVDDIDHLGNRRVRCVGELAENQFRAGLVRVERAVKERLGQAEADNLMPH 384 L+++RNG+GEVDDIDHLGNRR+R VGE+AENQFR GLVRVERAVKERL + D LMP Sbjct: 431 KLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQ 490 Query: 385 DLINSKPISAAIREFFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDV 444 D+IN+KPISAA++EFFGSSQLSQFMDQ NPLSEITHKRR+SALGPGGLTRERAGFEVRDV Sbjct: 491 DMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDV 550 Query: 445 HPTHYGRVCPIETPEGPNIGLINSLALYARLNEYGFLETPYRKVEGSKVTNQIDYLSAIE 504 HPTHYGRVCPIETPEGPNIGLINSL++YA+ NEYGFLETPYRKV VT++I YLSAIE Sbjct: 551 HPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIE 610 Query: 505 EGRYVIAQANATIDGEGKLSDELVSAREAGETILVSPERVQYMDVAPGQVVSVAASLIPF 564 EG YVIAQAN+ +D EG ++LV+ R GE+ L S ++V YMDV+ QVVSV ASLIPF Sbjct: 611 EGNYVIAQANSNLDEEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPF 670 Query: 565 LEHDDANRALMGANMQRQAVPCLRPEKPLVGTGIERTVAVDSGTTVQALRGGVVDYVDAG 624 LEHDDANRALMGANMQRQAVP LR +KPLVGTG+ER VAVDSG T A RGGVV YVDA Sbjct: 671 LEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGVVQYVDAS 730 Query: 625 RVVIRVNDDEAQAGEVGVDIYNLIKYTRSNQNTNINQRPIVKIGDRVAKHDVIADGASTD 684 R+VI+VN+DE GE G+DIYNL KYTRSNQNT INQ P V +G+ V + DV+ADG STD Sbjct: 731 RIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTD 790 Query: 685 MGELALGQNMLVAFMPWNGYNFEDSILISEKVVADDRYTSIHIEELSVVARDTKLGAEEI 744 +GELALGQNM VAFMPWNGYNFEDSIL+SE+VV +DR+T+IHI+EL+ V+RDTKLG EEI Sbjct: 791 LGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEI 850 Query: 745 TRDISNLAENQLARLDESGIVYIGAEVEAGDTLVGKVTPKGETQLTPEEKLLRAIFGEKA 804 T DI N+ E L++LDESGIVYIGAEV GD LVGKVTPKGETQLTPEEKLLRAIFGEKA Sbjct: 851 TADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKA 910 Query: 805 SDVKDTSLRVPSGMVGTVIDVQVFTREGIQRDKRAQQIIDDELKRYRLDLNDQLRIVEGD 864 SDVKD+SLRVP+G+ GTVIDVQVFTR+G+++DKRA +I + +LK+ + DL+++L+I+E Sbjct: 911 SDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAG 970 Query: 865 AFQRLERLLIGKVANGGPKKLVKGTKLDKAYLDDLDKFHWFDIRPADDDIANALEAIKES 924 F R+ +L+ GG V+ KLDK L + W ++ D++ N LE + E Sbjct: 971 LFSRIRAVLVA----GG----VEAEKLDK-----LPRDRWLELGLTDEEKQNQLEQLAEQ 1017 Query: 925 IAEKRHQFDLAFEEKRKKLTQGDELPPGVQKMVKVYLAVKRRLQPGDKMAGRHGNKGVVS 984 E +H+F+ E KR+K+TQGD+L PGV K+VKVYLAVKRR+QPGDKMAGRHGNKGV+S Sbjct: 1018 YDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVIS 1077 Query: 985 RILPIEDMPHMADGTPADIVLNPLGVPSRMNVGQVLEVHLGWAAKGLGLRLGEMVQAQAK 1044 +I PIEDMP+ +GTP DIVLNPLGVPSRMN+GQ+LE HLG AAKG+G ++ M++ Q + Sbjct: 1078 KINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQE 1137 Query: 1045 VAELRKFLTTIYN---ESGKQEELDSFTDEEIIELVENLKKGVPFATPVFDGAHEEETRR 1101 VA+LR+F+ Y+ + ++ +L +F+DEE++ L ENL+KG+P ATPVFDGA E E + Sbjct: 1138 VAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKE 1197 Query: 1102 MLDLAYPDPIAKQLGMTPSKNQVTMYDGRTGEAFERTVTVGYMHYLKLHHLVDDKMHARS 1161 +L +LG P+ Q+ +YDGRTGE FER VTVGYM+ LKL+HLVDDKMHARS Sbjct: 1198 LL----------KLGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARS 1247 Query: 1162 TGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVNGRTKVYEN 1221 TG YSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGA+Y LQEMLTVKSDDVNGRTK+Y+N Sbjct: 1248 TGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKN 1307 Query: 1222 LVKGDHVIDAGMPESFNVLVKEIRSLGIDIDLERE 1256 +V G+H ++ GMPESFNVL+KEIRSLGI+I+LE E Sbjct: 1308 IVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE 1342 >ECs4910 [K] COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit Ecs Escherichia coli O157:H7 Length = 1342 Score = 1621 bits (4198), Expect = 0.0, Method: Compositional matrix adjust. Identities = 802/1235 (64%), Positives = 975/1235 (78%), Gaps = 27/1235 (2%) Query: 25 DNFNLHAEGADMEFVSERLRGEVARFDITDKSGKVMGKLLFSARIIPYRGSWLDFEFDPK 84 DN G + VS+ R FD GK+L++ARIIPYRGSWLDFEFDPK Sbjct: 132 DNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPK 191 Query: 85 DILFFRVDRRRKMPVTILLKAIGMTSEQILANFFVFDNFNLHAEGADMEFVSERLRGEVA 144 D LF R+DRRRK+P TI+L+A+ T+EQIL FF F + ME V ERLRGE A Sbjct: 192 DNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQMELVPERLRGETA 251 Query: 145 RFDITDKSGKVMVAKDKRINAKHVRDIEAAGIKHISVPEDYLLGRVLAKNIVDPETGEVV 204 FDI + +GKV V K +RI A+H+R +E +K I VP +Y+ G+V+AK+ +D TGE++ Sbjct: 252 SFDI-EANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELI 310 Query: 205 ASANDELTEELLAKLREANISAIQTLYTNDLDQGGYISQTLRTDDTADQTAARVAIYRMM 264 +AN EL+ +LLAKL ++ I+TL+TNDLD G YIS+TLR D T D+ +A V IYRMM Sbjct: 311 CAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMM 370 Query: 265 RPGEPPTEESVEALFNGLFYSEDRYDLSAVGRMKFNRRVGRDELTGTMTLSNDDILAVIK 324 RPGEPPT E+ E+LF LF+SEDRYDLSAVGRMKFNR + R+E+ G+ LS DDI+ V+K Sbjct: 371 RPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLREEIEGSGILSKDDIIDVMK 430 Query: 325 ILVELRNGRGEVDDIDHLGNRRVRCVGELAENQFRAGLVRVERAVKERLGQAEADNLMPH 384 L+++RNG+GEVDDIDHLGNRR+R VGE+AENQFR GLVRVERAVKERL + D LMP Sbjct: 431 KLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQ 490 Query: 385 DLINSKPISAAIREFFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDV 444 D+IN+KPISAA++EFFGSSQLSQFMDQ NPLSEITHKRR+SALGPGGLTRERAGFEVRDV Sbjct: 491 DMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDV 550 Query: 445 HPTHYGRVCPIETPEGPNIGLINSLALYARLNEYGFLETPYRKVEGSKVTNQIDYLSAIE 504 HPTHYGRVCPIETPEGPNIGLINSL++YA+ NEYGFLETPYRKV VT++I YLSAIE Sbjct: 551 HPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIE 610 Query: 505 EGRYVIAQANATIDGEGKLSDELVSAREAGETILVSPERVQYMDVAPGQVVSVAASLIPF 564 EG YVIAQAN+ +D EG ++LV+ R GE+ L S ++V YMDV+ QVVSV ASLIPF Sbjct: 611 EGNYVIAQANSNLDEEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPF 670 Query: 565 LEHDDANRALMGANMQRQAVPCLRPEKPLVGTGIERTVAVDSGTTVQALRGGVVDYVDAG 624 LEHDDANRALMGANMQRQAVP LR +KPLVGTG+ER VAVDSG T A RGGVV YVDA Sbjct: 671 LEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGVVQYVDAS 730 Query: 625 RVVIRVNDDEAQAGEVGVDIYNLIKYTRSNQNTNINQRPIVKIGDRVAKHDVIADGASTD 684 R+VI+VN+DE GE G+DIYNL KYTRSNQNT INQ P V +G+ V + DV+ADG STD Sbjct: 731 RIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTD 790 Query: 685 MGELALGQNMLVAFMPWNGYNFEDSILISEKVVADDRYTSIHIEELSVVARDTKLGAEEI 744 +GELALGQNM VAFMPWNGYNFEDSIL+SE+VV +DR+T+IHI+EL+ V+RDTKLG EEI Sbjct: 791 LGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEI 850 Query: 745 TRDISNLAENQLARLDESGIVYIGAEVEAGDTLVGKVTPKGETQLTPEEKLLRAIFGEKA 804 T DI N+ E L++LDESGIVYIGAEV GD LVGKVTPKGETQLTPEEKLLRAIFGEKA Sbjct: 851 TADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKA 910 Query: 805 SDVKDTSLRVPSGMVGTVIDVQVFTREGIQRDKRAQQIIDDELKRYRLDLNDQLRIVEGD 864 SDVKD+SLRVP+G+ GTVIDVQVFTR+G+++DKRA +I + +LK+ + DL+++L+I+E Sbjct: 911 SDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAG 970 Query: 865 AFQRLERLLIGKVANGGPKKLVKGTKLDKAYLDDLDKFHWFDIRPADDDIANALEAIKES 924 F R+ +L+ GG V+ KLDK L + W ++ D++ N LE + E Sbjct: 971 LFSRIRAVLVA----GG----VEAEKLDK-----LPRDRWLELGLTDEEKQNQLEQLAEQ 1017 Query: 925 IAEKRHQFDLAFEEKRKKLTQGDELPPGVQKMVKVYLAVKRRLQPGDKMAGRHGNKGVVS 984 E +H+F+ E KR+K+TQGD+L PGV K+VKVYLAVKRR+QPGDKMAGRHGNKGV+S Sbjct: 1018 YDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVIS 1077 Query: 985 RILPIEDMPHMADGTPADIVLNPLGVPSRMNVGQVLEVHLGWAAKGLGLRLGEMVQAQAK 1044 +I PIEDMP+ +GTP DIVLNPLGVPSRMN+GQ+LE HLG AAKG+G ++ M++ Q + Sbjct: 1078 KINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQE 1137 Query: 1045 VAELRKFLTTIYN---ESGKQEELDSFTDEEIIELVENLKKGVPFATPVFDGAHEEETRR 1101 VA+LR+F+ Y+ + ++ +L +F+DEE++ L ENL+KG+P ATPVFDGA E E + Sbjct: 1138 VAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKE 1197 Query: 1102 MLDLAYPDPIAKQLGMTPSKNQVTMYDGRTGEAFERTVTVGYMHYLKLHHLVDDKMHARS 1161 +L +LG P+ Q+ +YDGRTGE FER VTVGYM+ LKL+HLVDDKMHARS Sbjct: 1198 LL----------KLGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARS 1247 Query: 1162 TGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVNGRTKVYEN 1221 TG YSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGA+Y LQEMLTVKSDDVNGRTK+Y+N Sbjct: 1248 TGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKN 1307 Query: 1222 LVKGDHVIDAGMPESFNVLVKEIRSLGIDIDLERE 1256 +V G+H ++ GMPESFNVL+KEIRSLGI+I+LE E Sbjct: 1308 IVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE 1342 >STM4153 [K] COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit Sty Salmonella typhimurium LT2 Length = 1342 Score = 1621 bits (4197), Expect = 0.0, Method: Compositional matrix adjust. Identities = 800/1235 (64%), Positives = 977/1235 (79%), Gaps = 27/1235 (2%) Query: 25 DNFNLHAEGADMEFVSERLRGEVARFDITDKSGKVMGKLLFSARIIPYRGSWLDFEFDPK 84 DN G + VS+ R FD GK+L++ARIIPYRGSWLDFEFDPK Sbjct: 132 DNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPK 191 Query: 85 DILFFRVDRRRKMPVTILLKAIGMTSEQILANFFVFDNFNLHAEGADMEFVSERLRGEVA 144 D LF R+DRRRK+P TI+L+A+ T+EQIL FF F + ME + ERLRGE A Sbjct: 192 DNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVVFEIRDNKLQMELIPERLRGETA 251 Query: 145 RFDITDKSGKVMVAKDKRINAKHVRDIEAAGIKHISVPEDYLLGRVLAKNIVDPETGEVV 204 FDI + +GKV V K +RI A+H+R +E IKHI VP +Y+ G+V++K+ VD TGE++ Sbjct: 252 SFDI-EANGKVYVEKGRRITARHIRQLEKDDIKHIEVPVEYIAGKVVSKDYVDESTGELI 310 Query: 205 ASANDELTEELLAKLREANISAIQTLYTNDLDQGGYISQTLRTDDTADQTAARVAIYRMM 264 +AN EL+ +LLAKL ++ I+TL+TNDLD G YIS+T+R D T D+ +A V IYRMM Sbjct: 311 CAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETVRVDPTNDRLSALVEIYRMM 370 Query: 265 RPGEPPTEESVEALFNGLFYSEDRYDLSAVGRMKFNRRVGRDELTGTMTLSNDDILAVIK 324 RPGEPPT E+ E+LF LF+SEDRYDLSAVGRMKFNR + RDE+ G+ LS DDI+ V+K Sbjct: 371 RPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLRDEIEGSGILSKDDIIDVMK 430 Query: 325 ILVELRNGRGEVDDIDHLGNRRVRCVGELAENQFRAGLVRVERAVKERLGQAEADNLMPH 384 L+++RNG+GEVDDIDHLGNRR+R VGE+AENQFR GLVRVERAVKERL + D LMP Sbjct: 431 KLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQ 490 Query: 385 DLINSKPISAAIREFFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDV 444 D+IN+KPISAA++EFFGSSQLSQFMDQ NPLSEITHKRR+SALGPGGLTRERAGFEVRDV Sbjct: 491 DMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDV 550 Query: 445 HPTHYGRVCPIETPEGPNIGLINSLALYARLNEYGFLETPYRKVEGSKVTNQIDYLSAIE 504 HPTHYGRVCPIETPEGPNIGLINSL++YA+ NEYGFLETPYR+V VT++I YLSAIE Sbjct: 551 HPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRRVVDGVVTDEIHYLSAIE 610 Query: 505 EGRYVIAQANATIDGEGKLSDELVSAREAGETILVSPERVQYMDVAPGQVVSVAASLIPF 564 EG YVIAQAN+ +D EG ++LV+ R GE+ L S ++V YMDV+ QVVSV ASLIPF Sbjct: 611 EGNYVIAQANSNLDDEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPF 670 Query: 565 LEHDDANRALMGANMQRQAVPCLRPEKPLVGTGIERTVAVDSGTTVQALRGGVVDYVDAG 624 LEHDDANRALMGANMQRQAVP LR +KPLVGTG+ER VAVDSG T A RGG V YVDA Sbjct: 671 LEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGTVQYVDAS 730 Query: 625 RVVIRVNDDEAQAGEVGVDIYNLIKYTRSNQNTNINQRPIVKIGDRVAKHDVIADGASTD 684 R+VI+VN+DE GE G+DIYNL KYTRSNQNT INQ P V +G+ V + DV+ADG STD Sbjct: 731 RIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTD 790 Query: 685 MGELALGQNMLVAFMPWNGYNFEDSILISEKVVADDRYTSIHIEELSVVARDTKLGAEEI 744 +GELALGQNM VAFMPWNGYNFEDSIL+SE+VV +DR+T+IHI+EL+ V+RDTKLG EEI Sbjct: 791 LGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEI 850 Query: 745 TRDISNLAENQLARLDESGIVYIGAEVEAGDTLVGKVTPKGETQLTPEEKLLRAIFGEKA 804 T DI N+ E L++LDESGIVYIGAEV GD LVGKVTPKGETQLTPEEKLLRAIFGEKA Sbjct: 851 TADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKA 910 Query: 805 SDVKDTSLRVPSGMVGTVIDVQVFTREGIQRDKRAQQIIDDELKRYRLDLNDQLRIVEGD 864 SDVKD+SLRVP+G+ GTVIDVQVFTR+G+++DKRA +I + +LK+ + DL+++L+I+E Sbjct: 911 SDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAG 970 Query: 865 AFQRLERLLIGKVANGGPKKLVKGTKLDKAYLDDLDKFHWFDIRPADDDIANALEAIKES 924 F R+ +L V++G V+ KLDK L + W ++ D++ N LE + E Sbjct: 971 LFSRIRAVL---VSSG-----VEAEKLDK-----LPRDRWLELGLTDEEKQNQLEQLAEQ 1017 Query: 925 IAEKRHQFDLAFEEKRKKLTQGDELPPGVQKMVKVYLAVKRRLQPGDKMAGRHGNKGVVS 984 E +H+F+ E KR+K+TQGD+L PGV K+VKVYLAVKRR+QPGDKMAGRHGNKGV+S Sbjct: 1018 YDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVIS 1077 Query: 985 RILPIEDMPHMADGTPADIVLNPLGVPSRMNVGQVLEVHLGWAAKGLGLRLGEMVQAQAK 1044 +I PIEDMP+ +GTP DIVLNPLGVPSRMN+GQ+LE HLG AAKG+G ++ M++ Q + Sbjct: 1078 KINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQE 1137 Query: 1045 VAELRKFLTTIYN---ESGKQEELDSFTDEEIIELVENLKKGVPFATPVFDGAHEEETRR 1101 VA+LR+F+ Y+ + ++ +L +F+D+E++ L ENL+KG+P ATPVFDGA E E + Sbjct: 1138 VAKLREFIQRAYDLGADVRQKVDLSTFSDDEVLRLAENLRKGMPIATPVFDGAKEAEIKE 1197 Query: 1102 MLDLAYPDPIAKQLGMTPSKNQVTMYDGRTGEAFERTVTVGYMHYLKLHHLVDDKMHARS 1161 +L +LG P+ Q+T++DGRTGE FER VTVGYM+ LKL+HLVDDKMHARS Sbjct: 1198 LL----------KLGDLPTSGQITLFDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARS 1247 Query: 1162 TGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVNGRTKVYEN 1221 TG YSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGA+Y LQEMLTVKSDDVNGRTK+Y+N Sbjct: 1248 TGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKN 1307 Query: 1222 LVKGDHVIDAGMPESFNVLVKEIRSLGIDIDLERE 1256 +V G+H ++ GMPESFNVL+KEIRSLGI+I+LE E Sbjct: 1308 IVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE 1342 >ZrpoB [K] COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit EcZ Escherichia coli O157:H7 EDL933 Length = 1342 Score = 1619 bits (4193), Expect = 0.0, Method: Compositional matrix adjust. Identities = 801/1235 (64%), Positives = 974/1235 (78%), Gaps = 27/1235 (2%) Query: 25 DNFNLHAEGADMEFVSERLRGEVARFDITDKSGKVMGKLLFSARIIPYRGSWLDFEFDPK 84 DN G + VS+ R FD GK+L++ARIIPYRGSWLDFEFDPK Sbjct: 132 DNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPK 191 Query: 85 DILFFRVDRRRKMPVTILLKAIGMTSEQILANFFVFDNFNLHAEGADMEFVSERLRGEVA 144 D LF R+DRRRK+P TI+L+A+ T+EQIL FF F + ME V ERLRGE A Sbjct: 192 DNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQMELVPERLRGETA 251 Query: 145 RFDITDKSGKVMVAKDKRINAKHVRDIEAAGIKHISVPEDYLLGRVLAKNIVDPETGEVV 204 FDI + +GKV V K +RI A+H+R +E +K I VP +Y+ G+V+AK+ +D TGE++ Sbjct: 252 SFDI-EANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELI 310 Query: 205 ASANDELTEELLAKLREANISAIQTLYTNDLDQGGYISQTLRTDDTADQTAARVAIYRMM 264 +AN EL+ +LLAKL ++ I+TL+TNDLD G YIS+TLR D T D+ +A V IYRMM Sbjct: 311 CAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMM 370 Query: 265 RPGEPPTEESVEALFNGLFYSEDRYDLSAVGRMKFNRRVGRDELTGTMTLSNDDILAVIK 324 RPGEPPT E+ E+LF LF+SEDRYDLSAVGRMKFNR + R+E+ G+ LS DDI+ V+K Sbjct: 371 RPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLREEIEGSGILSKDDIIDVMK 430 Query: 325 ILVELRNGRGEVDDIDHLGNRRVRCVGELAENQFRAGLVRVERAVKERLGQAEADNLMPH 384 L+++RNG+GEVDDIDHLGNRR+R VGE+AENQFR GLVRVERAVKERL + D LMP Sbjct: 431 KLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQ 490 Query: 385 DLINSKPISAAIREFFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDV 444 D+IN+KPISAA++EFFGSSQLSQFMDQ NPLSEITHKRR+SALGPGGLTRERAGFEVRDV Sbjct: 491 DMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDV 550 Query: 445 HPTHYGRVCPIETPEGPNIGLINSLALYARLNEYGFLETPYRKVEGSKVTNQIDYLSAIE 504 HPTHYGRVCPIETPEGPNIGLINSL++YA+ NEYGFLETPYRKV VT++I YLSAIE Sbjct: 551 HPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIE 610 Query: 505 EGRYVIAQANATIDGEGKLSDELVSAREAGETILVSPERVQYMDVAPGQVVSVAASLIPF 564 EG YVIAQAN+ +D EG ++LV+ R GE+ L S ++V YMDV+ QVVSV ASLIPF Sbjct: 611 EGNYVIAQANSNLDEEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPF 670 Query: 565 LEHDDANRALMGANMQRQAVPCLRPEKPLVGTGIERTVAVDSGTTVQALRGGVVDYVDAG 624 LEHDDANRALMGANMQRQAVP LR +KPLVGTG+ER VAVDSG T A RGGVV YVDA Sbjct: 671 LEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGVVQYVDAS 730 Query: 625 RVVIRVNDDEAQAGEVGVDIYNLIKYTRSNQNTNINQRPIVKIGDRVAKHDVIADGASTD 684 R+VI+VN+DE GE G+DIYNL KYTRSNQNT INQ P V +G+ V + DV+ADG STD Sbjct: 731 RIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTD 790 Query: 685 MGELALGQNMLVAFMPWNGYNFEDSILISEKVVADDRYTSIHIEELSVVARDTKLGAEEI 744 +GELALGQNM VAFMPWNGYNFEDSIL+SE+VV +DR+T+IHI+EL+ V+RDTKLG EEI Sbjct: 791 LGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEI 850 Query: 745 TRDISNLAENQLARLDESGIVYIGAEVEAGDTLVGKVTPKGETQLTPEEKLLRAIFGEKA 804 T DI N+ E L++LDESGIVYIGAEV GD LVGKVTPKGETQLTPEEKLLRAIFGEKA Sbjct: 851 TADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKA 910 Query: 805 SDVKDTSLRVPSGMVGTVIDVQVFTREGIQRDKRAQQIIDDELKRYRLDLNDQLRIVEGD 864 SDVKD+SLRVP+G+ GTVIDVQVFTR+G+++DKRA +I + + K+ + DL+++L+I+E Sbjct: 911 SDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQXKQAKKDLSEELQILEAG 970 Query: 865 AFQRLERLLIGKVANGGPKKLVKGTKLDKAYLDDLDKFHWFDIRPADDDIANALEAIKES 924 F R+ +L+ GG V+ KLDK L + W ++ D++ N LE + E Sbjct: 971 LFSRIRAVLVA----GG----VEAEKLDK-----LPRDRWLELGLTDEEKQNQLEQLAEQ 1017 Query: 925 IAEKRHQFDLAFEEKRKKLTQGDELPPGVQKMVKVYLAVKRRLQPGDKMAGRHGNKGVVS 984 E +H+F+ E KR+K+TQGD+L PGV K+VKVYLAVKRR+QPGDKMAGRHGNKGV+S Sbjct: 1018 YDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVIS 1077 Query: 985 RILPIEDMPHMADGTPADIVLNPLGVPSRMNVGQVLEVHLGWAAKGLGLRLGEMVQAQAK 1044 +I PIEDMP+ +GTP DIVLNPLGVPSRMN+GQ+LE HLG AAKG+G ++ M++ Q + Sbjct: 1078 KINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQE 1137 Query: 1045 VAELRKFLTTIYN---ESGKQEELDSFTDEEIIELVENLKKGVPFATPVFDGAHEEETRR 1101 VA+LR+F+ Y+ + ++ +L +F+DEE++ L ENL+KG+P ATPVFDGA E E + Sbjct: 1138 VAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKE 1197 Query: 1102 MLDLAYPDPIAKQLGMTPSKNQVTMYDGRTGEAFERTVTVGYMHYLKLHHLVDDKMHARS 1161 +L +LG P+ Q+ +YDGRTGE FER VTVGYM+ LKL+HLVDDKMHARS Sbjct: 1198 LL----------KLGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARS 1247 Query: 1162 TGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVNGRTKVYEN 1221 TG YSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGA+Y LQEMLTVKSDDVNGRTK+Y+N Sbjct: 1248 TGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKN 1307 Query: 1222 LVKGDHVIDAGMPESFNVLVKEIRSLGIDIDLERE 1256 +V G+H ++ GMPESFNVL+KEIRSLGI+I+LE E Sbjct: 1308 IVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE 1342