BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0479.p (447 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2348 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetr... 634 0.0 PA2326 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetr... 513 e-145 Cgl0986 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tet... 468 e-131 mlr9217 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tet... 275 1e-73 BS_yxeK [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tet... 275 2e-73 mll2278 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tet... 253 6e-67 AGl2773 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tet... 253 8e-67 SMb21691 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene te... 250 5e-66 mlr7299 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tet... 245 2e-64 AGpT161 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tet... 243 5e-64 >PA2348 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Pae Pseudomonas aeruginosa Length = 462 Score = 634 bits (1635), Expect = 0.0, Method: Compositional matrix adjust. Identities = 302/440 (68%), Positives = 358/440 (81%), Gaps = 1/440 (0%) Query: 1 MNCVSHINHGLWTHPRDRSQDYTDIAYWTDLARLLERGKFDGLFLADIVGVYDVYQGNTD 60 MNCV HINHGLWTHPRDRS DY + +WT+LARLLERG FDGLF+ADI+GVYDVYQG + Sbjct: 13 MNCVGHINHGLWTHPRDRSSDYRKLRHWTELARLLERGLFDGLFIADILGVYDVYQGGIE 72 Query: 61 LTLRETIQLPVNDPLMLVPAMAAVTEHLGFGVTANLTYEAPFLFARRMSTLDHLSRGRVG 120 +T RE +QLPVNDPLMLV AMA VTEHLGFGVTANLTYEAP+ FARR+STLDHLS GR+G Sbjct: 73 VTAREAVQLPVNDPLMLVSAMAGVTEHLGFGVTANLTYEAPYPFARRLSTLDHLSDGRIG 132 Query: 121 WNIVTGYLDSAARAMGLHEQLEHDQRYDRADEFMEVVYKLWEGSWEDGAVLRDRARRVYA 180 WNIVTGYL+SAA+AMG Q+EHD+RYDRADE++EV+YKLWEGSWED AVL DR RRVYA Sbjct: 133 WNIVTGYLESAAKAMGQSAQIEHDRRYDRADEYLEVLYKLWEGSWEDDAVLADRQRRVYA 192 Query: 181 DPAKVHKIAHHGDYYHVEGIHLSEPSRQRTPVLYQAGSSGRGQAFGARHAECVFISSQSK 240 P K+HKI HHG++Y VEG HL+EPS QRTPVL+QAGSS RG AF ARHAECVF+S Q++ Sbjct: 193 RPEKIHKIRHHGEFYQVEGYHLAEPSPQRTPVLFQAGSSERGLAFAARHAECVFVSGQTR 252 Query: 241 DATRKLVQSIRDGAVREGRDPDAIKIFMGLTVVTGRTEQQAQERYREYARYASPEAGLAH 300 +ATR+LVQ IR V GR + I+IFMG+ V+ T +A++++ EY RYASPEAGLAH Sbjct: 253 EATRQLVQRIRAAVVGAGRRAEDIRIFMGINVIVAATAAEARDKHAEYRRYASPEAGLAH 312 Query: 301 YSAGTGIDFSQYELDEPIRPAKTNAIESLTKVVTQPELNWTKRKLLQQLELGGRYASIVG 360 +++ +GID S+Y LDEPIR K NAIES+ K +T + T RKLL QL LGGRY ++VG Sbjct: 313 FASSSGIDLSRYGLDEPIRYEKNNAIESVVKNLTVARTDSTVRKLLDQLALGGRYVTLVG 372 Query: 361 APDRVADELESWVADTGIDGYNLTRTVTPESFEDFVELVIPVLQERGSYKREYAQGTLRE 420 P +VAD+LE W+ADTG+DG+NLTRTV PES+ DF++LV+P LQ RGSYK YA GTLRE Sbjct: 373 DPRQVADDLEGWIADTGLDGFNLTRTVEPESYADFIDLVVPELQARGSYKTAYAPGTLRE 432 Query: 421 KLFQRG-ATLPQEHVGAGFR 439 KLF G A L EH GA FR Sbjct: 433 KLFGDGRARLQAEHAGAAFR 452 >PA2326 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Pae Pseudomonas aeruginosa Length = 469 Score = 513 bits (1320), Expect = e-145, Method: Compositional matrix adjust. Identities = 244/441 (55%), Positives = 315/441 (71%), Gaps = 2/441 (0%) Query: 1 MNCVSHINHGLWTHPRDRSQDYTDIAYWTDLARLLERGKFDGLFLADIVGVYDVYQGNTD 60 MNCV H + GLW HPRDRS Y D+ YWTDLARLLERG+FDGLF+AD++G+YDV GN D Sbjct: 12 MNCVGHQSPGLWAHPRDRSSQYKDLEYWTDLARLLERGRFDGLFIADVLGIYDVLDGNGD 71 Query: 61 LTLRETIQLPVNDPLMLVPAMAAVTEHLGFGVTANLTYEAPFLFARRMSTLDHLSRGRVG 120 +R+ Q+PVNDPL L+ MAAVT HLGFG+TA+L++E P+ FARR+STLDHL++GR+G Sbjct: 72 AAIRQAAQVPVNDPLALITPMAAVTRHLGFGLTASLSFEHPYPFARRLSTLDHLTKGRIG 131 Query: 121 WNIVTGYLDSAARAMGLHEQLEHDQRYDRADEFMEVVYKLWEGSWEDGAVLRDRARRVYA 180 WN+VT YL+S AR +G QL+HD+RYD ADE+++V+YKL+EGSWEDGAVLRDR RR+++ Sbjct: 132 WNVVTSYLESGARNLGQQAQLDHDRRYDYADEYLQVLYKLFEGSWEDGAVLRDRRRRIFS 191 Query: 181 DPAKVHKIAHHGDYYHVEGIHLSEPSRQRTPVLYQAGSSGRGQAFGARHAECVFISSQSK 240 DP K+H+I H G+++ V GIHL EPS QRTPVLYQAG+S RG+ F A HAECVF+++ SK Sbjct: 192 DPGKIHEIRHVGEHFQVPGIHLCEPSPQRTPVLYQAGASSRGKRFAAEHAECVFVAAPSK 251 Query: 241 DATRKLVQSIRDGAVREGRDPDAIKIFMGLTVVTGRTEQQAQERYREYARYASPEAGLAH 300 ++ V IR GRDP + +F TVV G T+ +A+ ++ EY + S E LA Sbjct: 252 TVLKQAVADIRQRVAEAGRDPRKVLVFNLQTVVLGETDAKARAKFDEYRAFVSYEGALAL 311 Query: 301 YSAGTGIDFSQYELDEPIRPAKTNAIESLTKVVTQ--PELNWTKRKLLQQLELGGRYASI 358 S TGIDF QY D+ +R TNAI+S + + P WT R+L + +GG Sbjct: 312 ISGWTGIDFGQYRPDQVLRHIHTNAIQSAVEAFSSADPTRTWTVRELADWVGIGGFGPLF 371 Query: 359 VGAPDRVADELESWVADTGIDGYNLTRTVTPESFEDFVELVIPVLQERGSYKREYAQGTL 418 VG+P VAD L+ WV DT +DG+NL + E+F D VEL++P LQ+RG YK EYA GTL Sbjct: 372 VGSPATVADLLQEWVEDTDVDGFNLAYALAHETFSDVVELLVPELQKRGVYKTEYAPGTL 431 Query: 419 REKLFQRGATLPQEHVGAGFR 439 REKLF G LP H AG+R Sbjct: 432 REKLFGDGPRLPDSHPAAGYR 452 >Cgl0986 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Cgl Corynebacterium glutamicum Length = 487 Score = 468 bits (1205), Expect = e-131, Method: Compositional matrix adjust. Identities = 229/444 (51%), Positives = 300/444 (67%), Gaps = 2/444 (0%) Query: 1 MNCVSHINHGLWTHPRDRSQDYTDIAYWTDLARLLERGKFDGLFLADIVGVYDVYQGNTD 60 MNCV+H + GLWTHP+D+++DY + YW LA+ LE+G FDGLF+AD++G YDVY + + Sbjct: 21 MNCVAHQSPGLWTHPKDKARDYNTLDYWVHLAKTLEKGLFDGLFIADVLGTYDVYGSSNE 80 Query: 61 LTLRETIQLPVNDPLMLVPAMAAVTEHLGFGVTANLTYEAPFLFARRMSTLDHLSRGRVG 120 L Q+PVNDP++LV AMA T++LGFG+TA YE P+ FARR++TLDHL+ GRVG Sbjct: 81 AALSSGAQVPVNDPILLVSAMAYATKNLGFGITAGTAYEHPYPFARRLATLDHLTNGRVG 140 Query: 121 WNIVTGYLDSAARAMGLHEQLEHDQRYDRADEFMEVVYKLWEGSWEDGAVLRDRARRVYA 180 WN+VTGYL SAA+ MG +QL HD+RYD+ADE++EV+YKL EGSWED AV + V+ Sbjct: 141 WNVVTGYLPSAAQNMGDTDQLPHDERYDKADEYLEVIYKLLEGSWEDDAVQNNTETSVFT 200 Query: 181 DPAKVHKIAHHGDYYHVEGIHLSEPSRQRTPVLYQAGSSGRGQAFGARHAECVFISSQSK 240 D +KVH I HHG Y+ V GI ++EPS QRTPV+YQAG+S RG F +AE VFI+S + Sbjct: 201 DSSKVHAINHHGKYFDVPGIAITEPSVQRTPVIYQAGASPRGLKFAGENAEAVFINSSTV 260 Query: 241 DATRKLVQSIRDGAVREGRDPDAIKIFMGLTVVTGRTEQQAQERYREYARYASPEAGLAH 300 +A K V IR AV GRDP A+KIF T++TG TE AQ + EY+RY P GL Sbjct: 261 EAITKTVAKIRAAAVAAGRDPHAVKIFAMQTIITGETEADAQAKLEEYSRYIDPVGGLTL 320 Query: 301 YSAGTGIDFSQYELDEPIRPAKTNAIESLTKVVTQ--PELNWTKRKLLQQLELGGRYASI 358 S TG D SQY+LDEPI ++NAI+S ++ E WT RKL + +GG + Sbjct: 321 MSGWTGADLSQYDLDEPITNIESNAIQSTAATISNGTGEGAWTVRKLGEATGIGGFGPVL 380 Query: 359 VGAPDRVADELESWVADTGIDGYNLTRTVTPESFEDFVELVIPVLQERGSYKREYAQGTL 418 VG+ VA EL + +DG+NL +TP +FED V+ V+P LQ+ YK EYA G+L Sbjct: 381 VGSGANVAAELARIQDLSDVDGFNLAYAITPGTFEDVVDFVVPELQKLSRYKTEYAPGSL 440 Query: 419 REKLFQRGATLPQEHVGAGFRVGA 442 R KL +G L H GA +R+GA Sbjct: 441 RNKLLGKGDRLDDTHRGASYRLGA 464 >mlr9217 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Mlo Mesorhizobium loti Length = 426 Score = 275 bits (704), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 152/418 (36%), Positives = 229/418 (54%), Gaps = 11/418 (2%) Query: 8 NHGLWTHPRDRSQDYTDIAYWTDLARLLERGKFDGLFLADIVGVYDVYQGNTDLTLRETI 67 +H +W HP+ ++ + D A+W L R LE G+FDGLF AD++ ++ + T+ Sbjct: 15 HHAMWRHPQTENR-FLDPAFWETLGRTLEAGRFDGLFFADVLSFHN------ETTMTRGG 67 Query: 68 QLPVNDPLMLVPAMAAVTEHLGFGVTANLTYEAPFLFARRMSTLDHLSRGRVGWNIVTGY 127 Q+ + DP+ LV MA T +G GVT + T++ P+ AR +S+LD LS GR+ WNIVT + Sbjct: 68 QMSLLDPVPLVAMMARATSRIGLGVTLSTTFQDPYAIARVLSSLDVLSGGRIAWNIVTSF 127 Query: 128 LDSAARAMGLHEQLEHDQRYDRADEFMEVVYKLWEGSWEDGAVLRDRARRVYADPAKVHK 187 D A+ G L +RY+RA+E ++V LW G W DGA++ D+ + D AKV + Sbjct: 128 SDLDAQIFGEEALLPRSERYERAEEVLKVCLDLWTG-WADGALVLDKESGDFIDEAKVRR 186 Query: 188 IAHHGDYYHVEGIHLSEPSRQRTPVLYQAGSSGRGQAFGARHAECVFISSQSKDATRKLV 247 G Y G+ PS QR PV+ QAGSS RG+ F A HAE VF S ++ Sbjct: 187 TEIAGKYVGARGVFTVPPSPQRHPVIMQAGSSPRGRDFAASHAELVFTLQHSLPDMQEFY 246 Query: 248 QSIRDGAVREGRDPDAIKIFMGLTVVTGRTEQQAQERYREYARYASPEAGLAHYSAGTGI 307 ++D R GR+PD I + + + G T A+E+ P G+ S TG+ Sbjct: 247 AEMKDRVGRAGRNPDDCAILVSVDPIVGETNSLAREKQAYINDLVDPHVGIPFMSDHTGL 306 Query: 308 DFSQYELDEPI--RPAKTNAIESLTKVVTQPEL-NWTKRKLLQQLELGGRYASIVGAPDR 364 D SQY +D+PI PA+T + S ++ + N T + + + +VG P+ Sbjct: 307 DLSQYPVDKPIIDIPAETGSRGSFDIILQGTKANNLTLGEAAKHFAVSELCPQVVGTPET 366 Query: 365 VADELESWVADTGIDGYNLTRTVTPESFEDFVELVIPVLQERGSYKREYAQGTLREKL 422 VAD+L+ + + G DG+ +T T P SFE F V+P+LQ+RG +++EY TLRE + Sbjct: 367 VADQLQDFFENKGCDGFIVTPTEMPGSFEAFTRSVVPILQKRGLFRKEYPGSTLRETI 424 >BS_yxeK [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Bsu Bacillus subtilis Length = 441 Score = 275 bits (702), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 155/417 (37%), Positives = 232/417 (55%), Gaps = 20/417 (4%) Query: 12 WTHPRDRSQDYTDIAYWTDLARLLERGKFDGLFLADIVGVYDVYQGNTDLTLRETIQLPV 71 W HP S ++ Y+ +LA+ ERGK D LFLAD + + N L Sbjct: 24 WRHPDAPSDASMNLDYFKELAKTAERGKLDMLFLADSLSIDSKSHPNV---------LTR 74 Query: 72 NDPLMLVPAMAAVTEHLGFGVTANLTYEAPFLFARRMSTLDHLSRGRVGWNIVTGYLDSA 131 +P L+ A+A VT +G TA+ TY PF AR+ ++LDHLS GR GWN+VT ++S Sbjct: 75 FEPFTLLSALAQVTSKIGLTATASTTYSEPFHIARQFASLDHLSNGRAGWNVVTSSIEST 134 Query: 132 ARAMGLHEQLEHDQRYDRADEFMEVVYKLWEGSWEDGAVLRDRARRVYADPAKVHKIAHH 191 A + LEH RY RA+EF+E+V LW+ SWE+ A +R++ + D K+H++ H Sbjct: 135 ALNFSGEKHLEHHLRYQRAEEFVEIVKGLWD-SWEEDAFIRNKETGEFFDKEKMHELNHK 193 Query: 192 GDYYHVEGIHLSEPSRQRTPVLYQAGSSGRGQAFGARHAECVFISSQSKDATRKLVQSIR 251 G+Y+ V G + Q PV+ QAGSSG G+A A+ AE +F + ++ ++ QSI+ Sbjct: 194 GEYFSVRGPLNVSRTPQGQPVIIQAGSSGDGKALAAKTAEVIFTAQNHLESAQEFYQSIK 253 Query: 252 DGAVREGRDPDAIKIFMGLTVVTGRTEQQAQERYREYARYASPEAG---LAHYSAGTGID 308 + A GRDP+ I I G+ + TE+ AQ +Y+E P G L +Y GID Sbjct: 254 EQAAEFGRDPEKIAIMPGIFPIIADTEEAAQAKYKELQDLIIPSVGLQILQNYLG--GID 311 Query: 309 FSQYELDEP---IRPAKTNAIESLTKVVTQ--PELNWTKRKLLQQLELGGRYASIVGAPD 363 S Y LD P + +NA++S K+V + N T R+L + + + VG P+ Sbjct: 312 LSAYPLDGPLPKLDAEASNAVKSRFKLVQEMAERDNMTIRELYKYVAGSRGHHIFVGTPE 371 Query: 364 RVADELESWVADTGIDGYNLTRTVTPESFEDFVELVIPVLQERGSYKREYAQGTLRE 420 ++AD+++ WV DG+N+ + PE E FV+ V+P+LQERG +++EY TLRE Sbjct: 372 QLADKMQEWVDTKACDGFNIMPPLLPEGIEVFVDQVVPILQERGVFRKEYEGTTLRE 428 >mll2278 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Mlo Mesorhizobium loti Length = 450 Score = 253 bits (646), Expect = 6e-67, Method: Compositional matrix adjust. Identities = 148/418 (35%), Positives = 231/418 (55%), Gaps = 15/418 (3%) Query: 12 WTHPRDRSQDYTDIAYWTDLARLLERGKFDGLFLADIVGVYDVYQGNTDLTLRETIQLPV 71 W HPR ++ D Y+ +L + ER + D +F+AD V ++D + ++ Sbjct: 21 WRHPRAPGREVLDFDYYRELVQAAERARIDTIFVADHVSIWDSVKSGVAHYANARLE--- 77 Query: 72 NDPLMLVPAMAAVTEHLGFGVTANLTYEAPFLFARRMSTLDHLSRGRVGWNIVTGYLDSA 131 PL L+ A+AAVT+H+G TA+ +Y P+ AR ++LDH+S+GR WN+VT +D Sbjct: 78 --PLTLLSALAAVTKHIGLITTASSSYSEPYNVARLFASLDHISKGRASWNVVTSAMDEE 135 Query: 132 ARAMGLHEQLEHDQRYDRADEFMEVVYKLWEGSWEDGAVLRDRARRVYADPAKVHKIAHH 191 AR G +EH RY+RA EF+++V LW+ SWED A+L D+ +ADP KVH I H Sbjct: 136 ARNFGRDGNIEHAFRYERAGEFLDIVKALWD-SWEDEALLIDKETGYFADPDKVHPIDHK 194 Query: 192 GDYYHVEG-IHLSEPSRQRTPVLYQAGSSGRGQAFGARHAECVFISSQSKDATRKLVQSI 250 G ++ V G +++S P Q P++ QAGSS G+ F HA+ F +++ K Q I Sbjct: 195 GKHFKVRGPLNVSRPP-QGHPLIVQAGSSEDGKNFATAHADAHFAIYSTREDGIKYRQDI 253 Query: 251 RDGAVREGRDPDAIKIFMGLTVVTGRTEQQAQERYREYARYASP-EAGLAHYSAGTGIDF 309 + R GR P++ KI G+ + +E + +++ +EY + P + G+ S+ +GID Sbjct: 254 NERLARHGRRPESFKILPGILPIVAASEAEGRDK-QEYLQTLLPDQVGIDLLSSWSGIDL 312 Query: 310 SQYELDEPIRPAKTNAI-----ESLTKVVTQPELNWTKRKLLQQLELGGRYASIVGAPDR 364 S Y D P+ P + SL +V + N + R + ++L G ++ G P + Sbjct: 313 SAYPPDGPLPPLPDESTFNGGRTSLNRVKQWSKQNLSLRDIARKLANSGSVPTVAGTPKQ 372 Query: 365 VADELESWVADTGIDGYNLTRTVTPESFEDFVELVIPVLQERGSYKREYAQGTLREKL 422 +AD+LE W DG+NL + PE + +F E V+P LQ RG EYA GTLR++L Sbjct: 373 IADQLEDWFVSGAADGFNLMFPLLPEDWVNFAEQVVPELQRRGLVPTEYAPGTLRDRL 430 >AGl2773 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 450 Score = 253 bits (645), Expect = 8e-67, Method: Compositional matrix adjust. Identities = 149/417 (35%), Positives = 222/417 (53%), Gaps = 19/417 (4%) Query: 12 WTHPRDRSQDYTDIAYWTDLARLLERGKFDGLFLADIVGVYDVYQGNTDLTLRETIQLPV 71 W HP TDI + D+AR E K D +F AD V N R ++ Sbjct: 24 WRHPESEPLRVTDIKLYQDIARKAEAAKLDAIFFADA----PVLDANIRYAARHRLE--- 76 Query: 72 NDPLMLVPAMAAVTEHLGFGVTANLTYEAPFLFARRMSTLDHLSRGRVGWNIVTGYLDSA 131 P+ ++ A+AAVTE +GF TA+ TY P+ AR ++++DH+S GRVGWNIVT D+A Sbjct: 77 --PITMLAALAAVTEKIGFIATASTTYYEPYNLARLLASVDHISGGRVGWNIVTTSADAA 134 Query: 132 ARAMGLHEQLEHDQRYDRADEFMEVVYKLWEGSWEDGAVLRDRARRVYADPAKVHKIAHH 191 A L + H RY +A EF+EVV KLW+ SWED A++ DR ++AD ++H +H Sbjct: 135 AGNFNLQQHPPHADRYRQATEFVEVVTKLWD-SWEDDAIVADRESGLFADTDRIHPASHD 193 Query: 192 GDYYHVEGIHLSEPSRQRTPVLYQAGSSGRGQAFGARHAECVFISSQSKDATRKLVQSIR 251 G++Y V G S Q PV QAGSS G+ F AR+AE +F + Q+ ++ R I+ Sbjct: 194 GEFYRVRGALNLPRSPQGRPVYVQAGSSEDGRGFAARYAEAIFTAHQTLESARSFYSDIK 253 Query: 252 DGAVREGRDPDAIKIFMGLTVVTGRTEQQAQERYREYARYASPEAGLAHYSAGTGIDFSQ 311 GR+P +KI G++ TE++A++ + P L TGID S Sbjct: 254 RRVAATGRNPAHVKILPGISPFIASTEEEARKLEASFNDLIQPAFSLGQLQRITGIDLSS 313 Query: 312 YELDEPI--------RPAKTNAIESLTKVVTQPELNWTKRKLLQQLELGGRYASIVGAPD 363 +LD+P+ R ++ L V E N T R+LL +L G + I G P+ Sbjct: 314 ADLDQPLPKEAVEATRAQADSSRHQLVLDVIDRE-NPTIRQLLHRLAGGRGHKVISGTPE 372 Query: 364 RVADELESWVADTGIDGYNLTRTVTPESFEDFVELVIPVLQERGSYKREYAQGTLRE 420 +VAD +E+W + DG+N+ F+ FV+ V+P+L++RG ++ +Y TLR+ Sbjct: 373 QVADWIETWFREGAADGFNIMPPWLNGGFDIFVDEVVPILKQRGLFREDYEGDTLRD 429 >SMb21691 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Sme Sinorhizobium meliloti Length = 449 Score = 250 bits (638), Expect = 5e-66, Method: Compositional matrix adjust. Identities = 152/418 (36%), Positives = 225/418 (53%), Gaps = 16/418 (3%) Query: 12 WTHPRDRSQDYTDIAYWTDLARLLERGKFDGLFLAD--IVGVYDVYQGNTDLTLRETIQL 69 W HP + T+ + LA ERG FD FLAD VG+ GN + E Sbjct: 21 WRHPDAPADGATNFEFHRRLAETAERGLFDAYFLADNLSVGLGGREGGNAKIAGFE---- 76 Query: 70 PVNDPLMLVPAMAAVTEHLGFGVTANLTYEAPFLFARRMSTLDHLSRGRVGWNIVTGYLD 129 P+ L A+A +T HLGF TA+ TYE P+ AR+ ++LD LS GR GWN+VT D Sbjct: 77 ----PVTLFAALAPLTTHLGFIATASTTYEEPYTLARKFASLDLLSNGRAGWNVVTSAGD 132 Query: 130 SAARAMGLHEQLEHDQRYDRADEFMEVVYKLWEGSWEDGAVLRDRARRVYADPAKVHKIA 189 AR Q H RY+RA E +E V LW+ SWED A +RD+A + D +VH I Sbjct: 133 ETARNFNRETQPSHADRYERAHEHVETVKALWD-SWEDDAFIRDKATGRFFDAGRVHDID 191 Query: 190 HHGDYYHVEGIHLSEPSRQRTPVLYQAGSSGRGQAFGARHAECVFISSQSKDATRKLVQS 249 H G ++ V+G + Q PV+ QAG S G+ A AE +F + Q+ + ++ + Sbjct: 192 HKGKHFSVKGPLNAPRPVQGHPVVVQAGQSEDGRRLAAVSAEVIFTAHQNLASAQEFYRD 251 Query: 250 IRDGAVREGRDPDAIKIFMGLTVVTGRTEQQAQERYREYARYASPEAGLAHYSAGTG--I 307 I+ R GR+P+ + I G+ GRTE++A+ +Y E PE G+A + TG + Sbjct: 252 IKARVKRAGRNPEHVLIMPGVAPFVGRTEEEARSKYEELNALIVPEDGVALLNGLTGGTL 311 Query: 308 DFSQYELDEPIRPA-KTNAIESLTKVVTQ--PELNWTKRKLLQQLELGGRYASIVGAPDR 364 D + Y LD P+ + +T ++S ++ + E +T R+L Q + + ++VG+ ++ Sbjct: 312 DLTGYPLDGPLPVSNETEGMKSRQALIRKIADEHGFTIRQLYQWIATARGHYTVVGSAEQ 371 Query: 365 VADELESWVADTGIDGYNLTRTVTPESFEDFVELVIPVLQERGSYKREYAQGTLREKL 422 VAD+LE W DG+N+ P + +DFV+LVIP+LQ RG ++ Y TLRE L Sbjct: 372 VADQLEEWFLSEAADGFNILPPWLPGALDDFVDLVIPILQRRGLFRTAYEGRTLRENL 429 >mlr7299 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Mlo Mesorhizobium loti Length = 451 Score = 245 bits (625), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 157/428 (36%), Positives = 234/428 (54%), Gaps = 16/428 (3%) Query: 1 MNCVSHINHGLWTHPRDRSQDYTDIAYWTDLARLLERGKFDGLFLADIVGVYDVYQGNTD 60 M VS ++ G W +P + A+ A+ LE KFD F+AD + V ++ Sbjct: 13 MRPVS-LHTGAWRYPGAYPDANFNFAHLKRFAQTLEAAKFDAFFMADHLAVLNM----PI 67 Query: 61 LTLRETIQLPVNDPLMLVPAMAAVTEHLGFGVTANLTYEAPFLFARRMSTLDHLSRGRVG 120 LR + + +P L+ A+AAVT+H+G TA+ T++AP+ ARR ++LDH+S GR G Sbjct: 68 EALRRSHTVTSFEPFTLLSALAAVTDHIGLVATASTTFDAPYHIARRFASLDHISGGRAG 127 Query: 121 WNIVTGYLDSAARAMGLHEQLEHDQRYDRADEFMEVVYKLWEGSWEDGAVLRDRARRVYA 180 WNIVT AA GL E +EHD+RY RA EF +VV LW+ S+ D A +RD +Y Sbjct: 128 WNIVTTSNPDAALNFGLDEHVEHDERYHRAREFYDVVTGLWD-SFADDAFIRDAESGLYF 186 Query: 181 DPAKVHKIAHHGDYYHVEG-IHLSEPSRQRTPVLYQAGSSGRGQAFGARHAECVFISSQS 239 DPAK+H + H G++ V G ++++ P Q PV+ QAG+S G+ A AE +F + Sbjct: 187 DPAKLHVLDHKGEHLSVRGPLNIARPV-QGWPVIVQAGASEAGRQLAAETAEVIFAAHAD 245 Query: 240 KDATRKLVQSIRDGAVREGRDPDAIKIFMGLTVVTGRTEQQAQERYREYARYASPEAGLA 299 A + ++ A + GR D IKI G VV G + + A+ + + E+G+A Sbjct: 246 LAAGQHFFADVKGRAQKLGRSRDDIKILPGAFVVVGDSVEDARAKRAKLDSLVYYESGIA 305 Query: 300 HYSAGTGIDFSQYELDEPI-RPAKTNAIESLTKVVTQ--PELNWTKRKLLQQLELGGRYA 356 S G + S ++ D + +TNA +S + V + N T R+L Q+L G Y+ Sbjct: 306 SLSIALGHNASAFDPDAALPEIPETNASKSSRERVIELARNENLTVRQLAQRL---GGYS 362 Query: 357 SI--VGAPDRVADELESWVADTGIDGYNLTRTVTPESFEDFVELVIPVLQERGSYKREYA 414 + VG P +ADE+E W+ G DG+N+ P +DFVE V+P LQ RG ++R+Y Sbjct: 363 GLAFVGTPQIIADEMEKWLVTEGSDGFNIMFPYLPAGLDDFVEKVVPELQRRGIFRRQYE 422 Query: 415 QGTLREKL 422 TLRE L Sbjct: 423 GSTLRENL 430 >AGpT161 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 450 Score = 243 bits (621), Expect = 5e-64, Method: Compositional matrix adjust. Identities = 151/427 (35%), Positives = 225/427 (52%), Gaps = 26/427 (6%) Query: 10 GLWTHPRDRSQDYTDIAYWTDLARLLERGKFDGLFLADIVGVYDVY-QGNTDLTLRETIQ 68 G W P + D A + +AR E K D LF+AD + + D Y Q D + Sbjct: 14 GGWRLPESATSGGVDWALYKTVARRAEAAKLDMLFVADKLSIDDNYGQHFADTVKYRLVT 73 Query: 69 LPVNDPLMLVPAMAAVTEHLGFGVTANLTYEAPFLFARRMSTLDHLSRGRVGWNIVTGYL 128 P +PL + A+ AVT+H+G G T + +Y +P+ AR ++ +DH+S GR WN+VT Sbjct: 74 RP--EPLTTLAALGAVTDHIGIGGTISSSYASPYAAARMLANIDHISGGRAAWNLVTSVS 131 Query: 129 DSAARAMGLHEQLEHDQRYDRADEFMEVVYKLWEGSWEDGAVLRDRARRVYADPAKVHKI 188 D AR G + H++RY RA EF +V+ KLW+ SWE A++ D+ V+AD K H I Sbjct: 132 DGEARNFGREQHFGHEERYLRAIEFADVMGKLWD-SWEADALVLDKKSGVFADSTKFHYI 190 Query: 189 AHHGDYYHVEG-IHLSEPSRQRTPVLYQAGSSGRGQAFGARHAECVFISSQSKDATRKLV 247 H GD++ + G I++ P + R PVL QAG S R Q A++AE +F+ + R Sbjct: 191 DHEGDFFKIRGPINVPRPPQGR-PVLIQAGVSDRFQGIAAQNAEVIFVVHAELERARSFY 249 Query: 248 QSIRDGAVREGRDPDAIKIFMGLTVVTGRTEQQAQERYREYARYASPEAGLAHYSAGTGI 307 +S ++ V GR +A+K+ G+ V GRT ++A ++ RE PEAGL+ SA Sbjct: 250 KSFKEKVVEGGRSENAVKVLPGIVPVVGRTRKEALDKERELKELILPEAGLSFMSASMNF 309 Query: 308 DFSQYELDEP---IRPAKTNAIESLTKVVTQPELNWTKRKLLQQL---ELGGRYA----- 356 D +Q+ + P I T ++ V+ KR + Q++ E+G YA Sbjct: 310 DLAQFPQNAPFPDITDKITGSVGRFQYVI--------KRAIEQKMTVAEVGKWYAESLSF 361 Query: 357 -SIVGAPDRVADELESWVADTGIDGYNLTRTVTPESFEDFVELVIPVLQERGSYKREYAQ 415 + VG P+ VA +L W A DG+ + + F+E V+PVLQERG ++REY Sbjct: 362 FAPVGTPEEVASQLAHWYAQRACDGFVILPPYIRRDEDLFLEGVVPVLQERGLFRREYPG 421 Query: 416 GTLREKL 422 TLRE L Sbjct: 422 TTLRETL 428