BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0390.p (163 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0333 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins ... 199 3e-51 NMA0493 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins ... 117 1e-26 NMB1958 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins ... 114 1e-25 BH1577 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins B... 91 1e-18 BS_resA [OC] COG0526 Thiol-disulfide isomerase and thioredoxins ... 80 2e-15 aq_152 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins A... 77 1e-14 FN1123 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins F... 74 1e-13 BH2868 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins B... 74 2e-13 RSp0563 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins ... 72 5e-13 BS_yneN [OC] COG0526 Thiol-disulfide isomerase and thioredoxins ... 72 5e-13 >RSc0333 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Rso Ralstonia solanacearum Length = 213 Score = 199 bits (505), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 89/153 (58%), Positives = 115/153 (75%) Query: 9 VVAAIAAFTYFKVNAGNAAPDVTFTKLDGQQVNLKDLRGKVVMVNFWATSCTTCVGEMPQ 68 V+AA F + + P +FT LDGQ+++ +DL+GKV +VNFWATSC TCV EMP Sbjct: 58 VLAAAGWFGWRAFSPSQQVPAASFTLLDGQKLSTRDLKGKVYLVNFWATSCATCVKEMPN 117 Query: 69 MIDTYNKFKDRGLDFVAVAMSYDPPNYVLNYTETRKLPFKVALDPQDTLAKAFGDVKLTP 128 MI TYNKFK +GL+FVAVAM YDPP YV+NY++TR+LPFKVA+D A+AFGDV+LTP Sbjct: 118 MIQTYNKFKGQGLEFVAVAMRYDPPMYVMNYSQTRQLPFKVAMDADGAAARAFGDVQLTP 177 Query: 129 TTFVIDKQGNIIKRYVGEPQFAELHQLLEKALS 161 TTF++D+ G I+KRYVGEP++A LL L+ Sbjct: 178 TTFLVDRDGRILKRYVGEPEWAAFETLLRDTLA 210 >NMA0493 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins NmA Neisseria meningitidis Z2491 Length = 162 Score = 117 bits (293), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 63/162 (38%), Positives = 92/162 (56%), Gaps = 2/162 (1%) Query: 1 MIKLAALAVVAAIAAF-TYFKVNAGNAAPDVTFTKLDGQQVNLKDLRGKVVMVNFWATSC 59 M K+ AVVA I + AP + + L G+ V+ DL+GKV ++NFW SC Sbjct: 1 MKKILTAAVVALIGILLAIVLIPDSKTAPAFSLSDLHGKTVSNADLQGKVTLINFWFPSC 60 Query: 60 TTCVGEMPQMIDTYNKFKDRGLDFVAVAMSYDPPNYVLNYTETRKLPFKVALDPQDTLAK 119 CV EMP++I T N +K++ +AVA DP V Y + LPF V D + + Sbjct: 61 PGCVSEMPKIIKTANDYKNKNFQVLAVAQPIDPIESVRQYVKDYGLPFTVMYDADKAVGQ 120 Query: 120 AFGDVKLTPTTFVIDKQGNIIKRYVGEPQFAELHQLLEKALS 161 AFG ++ PT+ +I K+G I+K YVGEP F +L+Q ++ AL+ Sbjct: 121 AFG-TQVYPTSVLIGKKGEILKTYVGEPDFGKLYQEIDTALA 161 >NMB1958 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Nme Neisseria meningitidis MC58 Length = 166 Score = 114 bits (284), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 62/160 (38%), Positives = 89/160 (55%), Gaps = 2/160 (1%) Query: 1 MIKLAALAVVAAIAAF-TYFKVNAGNAAPDVTFTKLDGQQVNLKDLRGKVVMVNFWATSC 59 M K+ AVVA I + AP + L G+ V+ DL+GKV ++NFW SC Sbjct: 1 MKKILTAAVVALIGILLAIVLIPDSKTAPAFSLPDLHGKTVSNADLQGKVTLINFWFPSC 60 Query: 60 TTCVGEMPQMIDTYNKFKDRGLDFVAVAMSYDPPNYVLNYTETRKLPFKVALDPQDTLAK 119 CV EMP++I T N +K++ +AVA DP V Y + LPF V D + + Sbjct: 61 PGCVSEMPKIIKTANDYKNKNFQVLAVAQPIDPIESVRQYVKDYGLPFTVMYDADKAVGQ 120 Query: 120 AFGDVKLTPTTFVIDKQGNIIKRYVGEPQFAELHQLLEKA 159 AFG ++ PT+ +I K+G I+K YVGEP F +L+Q ++ A Sbjct: 121 AFG-TQVYPTSVLIGKKGEILKTYVGEPDFGKLYQEIDTA 159 >BH1577 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Bha Bacillus halodurans Length = 176 Score = 90.9 bits (224), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 45/152 (29%), Positives = 82/152 (53%), Gaps = 10/152 (6%) Query: 2 IKLAALAVVAAIAAFTYFK--------VNAGNAAPDVTFTKLDGQQVNLKDLRGKVVMVN 53 ++L+ LAV++ +T++ AG A + L+G+ + L++L GK V +N Sbjct: 9 MRLSILAVISVALGYTFYSNFFADRSLARAGEQAVNFVLEDLEGESIELRELEGKGVFLN 68 Query: 54 FWATSCTTCVGEMPQMIDTYNKFKDRGLDFVAVAMSYDPPNYVLNYTETRKLPFKVALDP 113 FW T C C EMP M Y ++K++G++ +AV + +P V + + L F + +D Sbjct: 69 FWGTYCPPCEREMPHMEKLYGEYKEQGVEIIAVNAN-EPELTVQRFVDRYGLSFPIVIDK 127 Query: 114 QDTLAKAFGDVKLTPTTFVIDKQGNIIKRYVG 145 + A+G ++ PTT +I++ G I+K + G Sbjct: 128 GLNVIDAYG-IRPLPTTILINEHGEIVKVHTG 158 >BS_resA [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Bsu Bacillus subtilis Length = 181 Score = 79.7 bits (195), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 43/130 (33%), Positives = 70/130 (53%), Gaps = 2/130 (1%) Query: 27 APDVTFTKLDGQQVNLKDLRGKVVMVNFWATSCTTCVGEMPQMIDTYNKFKDRGLDFVAV 86 AP+ +G+++ L DL+GK V +NFW T C C E P M + Y FK +G++ VAV Sbjct: 44 APNFVLEDTNGKRIELSDLKGKGVFLNFWGTWCEPCKKEFPYMANQYKHFKSQGVEIVAV 103 Query: 87 AMSYDPPNYVLNYTETRKLPFKVALDPQDTLAKAFGDVKLTPTTFVIDKQGNIIKRYVGE 146 + + V N+ ++ + F V LD + A+ DV PTTF+I+ +G ++K G Sbjct: 104 NVG-ESKIAVHNFMKSYGVNFPVVLDTDRQVLDAY-DVSPLPTTFLINPEGKVVKVVTGT 161 Query: 147 PQFAELHQLL 156 + +H + Sbjct: 162 MTESMIHDYM 171 >aq_152 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Aae Aquifex aeolicus Length = 146 Score = 77.4 bits (189), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 34/86 (39%), Positives = 55/86 (63%), Gaps = 3/86 (3%) Query: 24 GNAAPDVTFTKLDGQQVNLKDLRGKVVMVNFWATSCTTCVGEMPQMIDTYNKFKDRGLDF 83 G P+VT T DG++V++++ +GKV+++NFWAT C C E+P + Y K++DRG + Sbjct: 37 GQKIPNVTLTTPDGKKVSIEEFKGKVLLINFWATWCPPCKEEIPMFKEIYEKYRDRGFEI 96 Query: 84 VAVAMSYDPPNYVLNYTETRKLPFKV 109 +A+ M DP N + + + LPF V Sbjct: 97 LAINM--DPEN-LTGFLKNNPLPFPV 119 >FN1123 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Fnu Fusobacterium nucleatum Length = 157 Score = 74.3 bits (181), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 45/151 (29%), Positives = 75/151 (49%), Gaps = 14/151 (9%) Query: 24 GNAA-PDVTFTKLDGQQVNLKDLRGKVVMVNFWATSCTTCVGEMPQMIDTYNKFKDRGLD 82 GN P++ G++ NL+D +GKVVM+NFW + C+ C GEMP++++ Y ++ + D Sbjct: 5 GNVTLPNIELVDQYGKKHNLEDYKGKVVMINFWVSWCSDCKGEMPKVVELYKEYGENKKD 64 Query: 83 F----VAVAMSYDPPNY--------VLNYTETRKLPFKVALDPQDTLAKAFGDVKLTPTT 130 VA +S + PN +L Y K F D + +++ P+T Sbjct: 65 LIILGVATPISKEYPNNKDKIDKKALLKYIADNKYVFPSLFDETGKTYAEY-EIEEYPST 123 Query: 131 FVIDKQGNIIKRYVGEPQFAELHQLLEKALS 161 F+ID+ G++ G EL Q +E L+ Sbjct: 124 FIIDRNGHLKVYIKGAISKEELKQNIESVLN 154 >BH2868 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Bha Bacillus halodurans Length = 184 Score = 73.6 bits (179), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 38/127 (29%), Positives = 70/127 (55%), Gaps = 3/127 (2%) Query: 21 VNAGNAAPDVTFTKLDGQQVNLKDLRGKVVMVNFWATSCTTCVGEMPQMIDTYNKFKDRG 80 V G A + T L+GQ V+L LRG+ V+++F+AT C C EMP ++ +++ +G Sbjct: 45 VQVGQRAVPFSLTTLEGQVVDLSSLRGQPVILHFFATWCPVCQDEMPSLVKLDKEYRQKG 104 Query: 81 LDFVAVAMSYDPPNY--VLNYTETRKLPFKVALDPQDTLAKAFGDVKLTPTTFVIDKQGN 138 F+A+ ++ + V + + + F LD + + + + + PTT ++D++G Sbjct: 105 GQFLAINLTNQESSIKDVRAFVQHYRAEFDPLLDTDGEVMETYQVIGI-PTTLILDEEGT 163 Query: 139 IIKRYVG 145 I+KRY G Sbjct: 164 IVKRYNG 170 >RSp0563 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Rso Ralstonia solanacearum Length = 185 Score = 72.0 bits (175), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 42/134 (31%), Positives = 66/134 (49%), Gaps = 4/134 (2%) Query: 8 AVVAAIAAFTYFKVNAGNAAPDVTFTKLDGQQVNLKDLRGKVVMVNFWATSCTTCVGEMP 67 +V+ + A + G AP + LDG++++ +DLRG+VV++ FWAT C C E+P Sbjct: 30 GLVSRLPAAHAASLEVGRPAPPLVLHTLDGRRISTEDLRGQVVVLTFWATWCEPCRTELP 89 Query: 68 QMIDTYNKFKDRGLDFVAVAMSYDPPNYVLNYTET-RKLPFKVALDPQDTLAKAFGDVKL 126 + + D GL + S D P+ + E KL F V L A +G + Sbjct: 90 LLSAYAARHADLGLRV--LGFSLDEPDELPAVREVGAKLSFPVGLL-GSPYAGGYGRIWR 146 Query: 127 TPTTFVIDKQGNII 140 P F ID+QG ++ Sbjct: 147 LPVNFTIDRQGLLV 160 >BS_yneN [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Bsu Bacillus subtilis Length = 170 Score = 72.0 bits (175), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 45/139 (32%), Positives = 72/139 (51%), Gaps = 5/139 (3%) Query: 21 VNAGNAAPDVTFTKLDGQQVNLKDLRGKVVMVNFWATSCTTCVGEMPQMIDTYNKFKDRG 80 + G APD + L G++ +L+D +GK V++NFWAT C C EMP M ++ D+ Sbjct: 33 IQEGQQAPDFSLKTLSGEKSSLQDAKGKKVLLNFWATWCKPCRQEMPAMEKLQKEYADK- 91 Query: 81 LDFVAVAMSY--DPPNYVLNYTETRKLPFKVALDPQDTLAKAFGDVKLTPTTFVIDKQGN 138 L VAV + V + +T L F + +D + A +V PTT+++D++G Sbjct: 92 LAVVAVNFTSAEKSEKQVRAFADTYDLTFPILIDKKGINADY--NVMSYPTTYILDEKGV 149 Query: 139 IIKRYVGEPQFAELHQLLE 157 I +VG E+ Q L+ Sbjct: 150 IQDIHVGTMTKKEMEQKLD 168