BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0388.p (198 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value NMB2090 [G] COG0279 Phosphoheptose isomerase Nme Neisseria menin... 240 1e-63 NMA0340 [G] COG0279 Phosphoheptose isomerase NmA Neisseria menin... 240 1e-63 PA4425 [G] COG0279 Phosphoheptose isomerase Pae Pseudomonas aeru... 230 2e-60 VC0579 [G] COG0279 Phosphoheptose isomerase Vch Vibrio cholerae 216 3e-56 yraO [G] COG0279 Phosphoheptose isomerase Eco Escherichia coli K12 197 1e-50 ZyraO [G] COG0279 Phosphoheptose isomerase EcZ Escherichia coli ... 197 1e-50 ECs4030 [G] COG0279 Phosphoheptose isomerase Ecs Escherichia col... 197 1e-50 STM3266 [G] COG0279 Phosphoheptose isomerase Sty Salmonella typh... 192 4e-49 YPO3550 [G] COG0279 Phosphoheptose isomerase Ype Yersinia pestis 191 8e-49 aq_908 [G] COG0279 Phosphoheptose isomerase Aae Aquifex aeolicus 177 2e-44 >NMB2090 [G] COG0279 Phosphoheptose isomerase Nme Neisseria meningitidis MC58 Length = 197 Score = 240 bits (613), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 113/188 (60%), Positives = 141/188 (75%) Query: 5 RILAHFQESADLKMKAASVLAQPIEQAIELMFTALSNGNKILACGNGGSAADSQHFAAEL 64 R+ AHF ES K +A VL +P QA ELM L N KILACGNGGSAAD+QHFAAE+ Sbjct: 7 RVAAHFAESIRAKQEAGKVLVEPTVQAAELMLQCLMNDGKILACGNGGSAADAQHFAAEM 66 Query: 65 VGRFERERLPLPALALTTDTSILTAVGNDYSYQEIFSKQVQAFGQSGDILLAFSTSGNSG 124 GRFE+ER+ L A+ALTTDTS LTA+GNDY + +FSKQV+A G++GD+L+ STSGNS Sbjct: 67 TGRFEKERMELAAVALTTDTSALTAIGNDYGFDHVFSKQVRALGRAGDVLVGISTSGNSA 126 Query: 125 NILAAIEVAHERDMRVVALTGKGGGKIGKVLNDADVHICVPHDRTARIQEVHLVTLHCIC 184 N++ A++ AHERDM V+ALTG+ GGKI +L D DV + VPH RTARIQE H++ +H +C Sbjct: 127 NVIEAVKAAHERDMHVIALTGRDGGKIAAILKDTDVLLNVPHPRTARIQENHILLIHAMC 186 Query: 185 DGIDVALF 192 D ID L Sbjct: 187 DCIDSVLL 194 >NMA0340 [G] COG0279 Phosphoheptose isomerase NmA Neisseria meningitidis Z2491 Length = 197 Score = 240 bits (613), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 113/188 (60%), Positives = 141/188 (75%) Query: 5 RILAHFQESADLKMKAASVLAQPIEQAIELMFTALSNGNKILACGNGGSAADSQHFAAEL 64 R+ AHF ES K +A VL +P QA ELM L N KILACGNGGSAAD+QHFAAE+ Sbjct: 7 RVAAHFAESIRAKQEAGKVLVEPTVQAAELMLQCLMNDGKILACGNGGSAADAQHFAAEM 66 Query: 65 VGRFERERLPLPALALTTDTSILTAVGNDYSYQEIFSKQVQAFGQSGDILLAFSTSGNSG 124 GRFE+ER+ L A+ALTTDTS LTA+GNDY + +FSKQV+A G++GD+L+ STSGNS Sbjct: 67 TGRFEKERMELAAVALTTDTSALTAIGNDYGFDHVFSKQVRALGRAGDVLVGISTSGNSA 126 Query: 125 NILAAIEVAHERDMRVVALTGKGGGKIGKVLNDADVHICVPHDRTARIQEVHLVTLHCIC 184 N++ A++ AHERDM V+ALTG+ GGKI +L D DV + VPH RTARIQE H++ +H +C Sbjct: 127 NVIEAVKAAHERDMHVIALTGRDGGKIAAILKDTDVLLNVPHPRTARIQENHILLIHAMC 186 Query: 185 DGIDVALF 192 D ID L Sbjct: 187 DCIDSVLL 194 >PA4425 [G] COG0279 Phosphoheptose isomerase Pae Pseudomonas aeruginosa Length = 197 Score = 230 bits (586), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 112/191 (58%), Positives = 141/191 (73%) Query: 5 RILAHFQESADLKMKAASVLAQPIEQAIELMFTALSNGNKILACGNGGSAADSQHFAAEL 64 RI FQ S + K +A VL IEQA +M AL N KIL+CGNGGSA D+QHF++EL Sbjct: 6 RIRQLFQASIETKQQALEVLPPYIEQASLVMVNALLNEGKILSCGNGGSAGDAQHFSSEL 65 Query: 65 VGRFERERLPLPALALTTDTSILTAVGNDYSYQEIFSKQVQAFGQSGDILLAFSTSGNSG 124 + RFERER LPA+ALTTD+S +T++ NDYSY E+FSKQ++A GQ GD+LLA STSGNS Sbjct: 66 LNRFERERPSLPAVALTTDSSTITSIANDYSYNEVFSKQIRALGQPGDVLLAISTSGNSA 125 Query: 125 NILAAIEVAHERDMRVVALTGKGGGKIGKVLNDADVHICVPHDRTARIQEVHLVTLHCIC 184 N++ AI+ AH+R+M VVALTG+ GG + +L DV I VP TARIQEVHL+ +HC+C Sbjct: 126 NVIQAIQAAHDREMLVVALTGRDGGGMASLLLPEDVEIRVPSKITARIQEVHLLAIHCLC 185 Query: 185 DGIDVALFGDD 195 D ID LFG + Sbjct: 186 DLIDRQLFGSE 196 >VC0579 [G] COG0279 Phosphoheptose isomerase Vch Vibrio cholerae Length = 196 Score = 216 bits (550), Expect = 3e-56, Method: Compositional matrix adjust. Identities = 109/189 (57%), Positives = 134/189 (70%), Gaps = 2/189 (1%) Query: 10 FQESADLKMKAASVLAQPIEQAIELMFTALSNGNKILACGNGGSAADSQHFAAELVGRFE 69 F ES +++ AA L I A + M +L NG+KIL CGNGGS+ ++Q F + L+ RFE Sbjct: 9 FTESIQIQIAAAEALPDAIMHAAQAMVASLLNGHKILCCGNGGSSVNAQQFVSCLLNRFE 68 Query: 70 RERLPLPALALTTDTSILTAVGNDYSYQEIFSKQVQAFGQSGDILLAFSTSGNSGNILAA 129 ER LP +ALT D + LTAV NDY YQEIFSKQV+AFGQ GDILLA STSGNS NI+ A Sbjct: 69 TERPSLPGMALTADNTTLTAVANDYHYQEIFSKQVRAFGQPGDILLAISTSGNSKNIIKA 128 Query: 130 IEVAHERDMRVVALTGKGGGKIGKVLNDADVHICVPHDRTARIQEVHLVTLHCICDGIDV 189 +E A RDM ++ALTGK GG++ +L + DV I +P RTARI EVH+VTLHC+CD ID Sbjct: 129 MEAAVTRDMTIIALTGKDGGEMAGLLGENDVEIRIPSHRTARIHEVHMVTLHCLCDLIDQ 188 Query: 190 ALFGDDAHE 198 LF AHE Sbjct: 189 VLF--PAHE 195 >yraO [G] COG0279 Phosphoheptose isomerase Eco Escherichia coli K12 Length = 196 Score = 197 bits (501), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 97/188 (51%), Positives = 131/188 (69%) Query: 5 RILAHFQESADLKMKAASVLAQPIEQAIELMFTALSNGNKILACGNGGSAADSQHFAAEL 64 RI A F ES ++ AA L I +A + +L NGNKIL CGNG SAA++QHFAA + Sbjct: 4 RIKACFTESIQTQIAAAEALPDAISRAAMTLVQSLLNGNKILCCGNGTSAANAQHFAASM 63 Query: 65 VGRFERERLPLPALALTTDTSILTAVGNDYSYQEIFSKQVQAFGQSGDILLAFSTSGNSG 124 + RFE ER LPA+AL TD +LTA+ ND + E+++KQV+A G +GD+LLA ST GNS Sbjct: 64 INRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQVRALGHAGDVLLAISTRGNSR 123 Query: 125 NILAAIEVAHERDMRVVALTGKGGGKIGKVLNDADVHICVPHDRTARIQEVHLVTLHCIC 184 +I+ A+E A RDM +VALTG GG++ +L DV I +P R+ARIQE+H++T++C+C Sbjct: 124 DIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVEIRIPSHRSARIQEMHMLTVNCLC 183 Query: 185 DGIDVALF 192 D ID LF Sbjct: 184 DLIDNTLF 191 >ZyraO [G] COG0279 Phosphoheptose isomerase EcZ Escherichia coli O157:H7 EDL933 Length = 196 Score = 197 bits (501), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 97/188 (51%), Positives = 131/188 (69%) Query: 5 RILAHFQESADLKMKAASVLAQPIEQAIELMFTALSNGNKILACGNGGSAADSQHFAAEL 64 RI A F ES ++ AA L I +A + +L NGNKIL CGNG SAA++QHFAA + Sbjct: 4 RIKACFTESIQTQIAAAEALPDAISRAAMTLVQSLLNGNKILCCGNGTSAANAQHFAASM 63 Query: 65 VGRFERERLPLPALALTTDTSILTAVGNDYSYQEIFSKQVQAFGQSGDILLAFSTSGNSG 124 + RFE ER LPA+AL TD +LTA+ ND + E+++KQV+A G +GD+LLA ST GNS Sbjct: 64 INRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQVRALGHAGDVLLAISTRGNSR 123 Query: 125 NILAAIEVAHERDMRVVALTGKGGGKIGKVLNDADVHICVPHDRTARIQEVHLVTLHCIC 184 +I+ A+E A RDM +VALTG GG++ +L DV I +P R+ARIQE+H++T++C+C Sbjct: 124 DIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVEIRIPSHRSARIQEMHMLTVNCLC 183 Query: 185 DGIDVALF 192 D ID LF Sbjct: 184 DLIDNTLF 191 >ECs4030 [G] COG0279 Phosphoheptose isomerase Ecs Escherichia coli O157:H7 Length = 196 Score = 197 bits (501), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 97/188 (51%), Positives = 131/188 (69%) Query: 5 RILAHFQESADLKMKAASVLAQPIEQAIELMFTALSNGNKILACGNGGSAADSQHFAAEL 64 RI A F ES ++ AA L I +A + +L NGNKIL CGNG SAA++QHFAA + Sbjct: 4 RIKACFTESIQTQIAAAEALPDAISRAAMTLVQSLLNGNKILCCGNGTSAANAQHFAASM 63 Query: 65 VGRFERERLPLPALALTTDTSILTAVGNDYSYQEIFSKQVQAFGQSGDILLAFSTSGNSG 124 + RFE ER LPA+AL TD +LTA+ ND + E+++KQV+A G +GD+LLA ST GNS Sbjct: 64 INRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQVRALGHAGDVLLAISTRGNSR 123 Query: 125 NILAAIEVAHERDMRVVALTGKGGGKIGKVLNDADVHICVPHDRTARIQEVHLVTLHCIC 184 +I+ A+E A RDM +VALTG GG++ +L DV I +P R+ARIQE+H++T++C+C Sbjct: 124 DIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVEIRIPSHRSARIQEMHMLTVNCLC 183 Query: 185 DGIDVALF 192 D ID LF Sbjct: 184 DLIDNTLF 191 >STM3266 [G] COG0279 Phosphoheptose isomerase Sty Salmonella typhimurium LT2 Length = 196 Score = 192 bits (488), Expect = 4e-49, Method: Compositional matrix adjust. Identities = 95/188 (50%), Positives = 129/188 (68%) Query: 5 RILAHFQESADLKMKAASVLAQPIEQAIELMFTALSNGNKILACGNGGSAADSQHFAAEL 64 RI F ES ++ AA L I +A + +L NGNKIL CGNG SAA++QHFAA + Sbjct: 4 RIKVCFTESIQTQIAAAEALPDAISRAAMTLVHSLLNGNKILCCGNGTSAANAQHFAASM 63 Query: 65 VGRFERERLPLPALALTTDTSILTAVGNDYSYQEIFSKQVQAFGQSGDILLAFSTSGNSG 124 + RFE ER LPA+AL TD +LTA+ ND + E+++KQV+A G +GD+LLA ST GNS Sbjct: 64 INRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQVRALGHAGDVLLAISTRGNSR 123 Query: 125 NILAAIEVAHERDMRVVALTGKGGGKIGKVLNDADVHICVPHDRTARIQEVHLVTLHCIC 184 +I+ A+E A RDM +VALTG GG++ +L DV I +P +ARIQE+H++T++C+C Sbjct: 124 DIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVEIRIPSHHSARIQEMHMLTVNCLC 183 Query: 185 DGIDVALF 192 D ID LF Sbjct: 184 DLIDNTLF 191 >YPO3550 [G] COG0279 Phosphoheptose isomerase Ype Yersinia pestis Length = 196 Score = 191 bits (485), Expect = 8e-49, Method: Compositional matrix adjust. Identities = 95/188 (50%), Positives = 128/188 (68%) Query: 5 RILAHFQESADLKMKAASVLAQPIEQAIELMFTALSNGNKILACGNGGSAADSQHFAAEL 64 RI F ES ++ AA L I A + +L NGNKIL CGNG SAA++QHFAA + Sbjct: 4 RIKGCFTESIQTQIAAAEALPDAISCAAMALVQSLLNGNKILCCGNGTSAANAQHFAASM 63 Query: 65 VGRFERERLPLPALALTTDTSILTAVGNDYSYQEIFSKQVQAFGQSGDILLAFSTSGNSG 124 + RFE ER LPA+AL D +LTA+ ND + E+++KQV+A GQ+GD+LLA ST GNS Sbjct: 64 INRFETERPSLPAIALNADNVVLTAITNDRLHDEVYAKQVRALGQAGDVLLAISTRGNSR 123 Query: 125 NILAAIEVAHERDMRVVALTGKGGGKIGKVLNDADVHICVPHDRTARIQEVHLVTLHCIC 184 +I+ A+E A RDM +VALTG GG++ +L DV I +P R AR+QE+H++T++C+C Sbjct: 124 DIVKAVEAAVTRDMTIVALTGYDGGELAGLLGQLDVEIRIPSHRGARVQELHMLTVNCLC 183 Query: 185 DGIDVALF 192 D ID LF Sbjct: 184 DLIDNTLF 191 >aq_908 [G] COG0279 Phosphoheptose isomerase Aae Aquifex aeolicus Length = 191 Score = 177 bits (448), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 86/179 (48%), Positives = 122/179 (68%), Gaps = 3/179 (1%) Query: 10 FQESADLKMKAASVLAQPIEQAIELMFTALSNGNKILACGNGGSAADSQHFAAELVGRFE 69 F+ESA++K+ + AQ I ++ TAL +GNK+L GNGGSAAD+QH AAELVGRF+ Sbjct: 9 FRESAEVKLAFVELYAQQIVDVAGIIATALKDGNKVLLFGNGGSAADAQHIAAELVGRFK 68 Query: 70 RERLPLPALALTTDTSILTAVGNDYSYQEIFSKQVQAFGQSGDILLAFSTSGNSGNILAA 129 +ER PLPA+ALTTDTSILTA+GNDY ++ IF +QV+A GD+ + +TSGNS N++ Sbjct: 69 KERRPLPAIALTTDTSILTALGNDYGFETIFERQVEALCMPGDVAIGITTSGNSENVIRG 128 Query: 130 IEVAHERDMRVVALTGKGGGKIGKVLNDADVHICVPHDRTARIQEVHLVTLHCICDGID 188 ++ AH+ +A TG+ GGK+ ++ A VP T RIQE H+ H +C+ ++ Sbjct: 129 LKKAHDLGATTIAFTGRNGGKVAQI---AHYTFIVPSYETQRIQECHITLGHVLCELVE 184