BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0319.p (1051 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value STM3391 [V] COG0841 Cation/multidrug efflux pump Sty Salmonella ... 1275 0.0 YPO3043 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pe... 1272 0.0 CC0807 [V] COG0841 Cation/multidrug efflux pump Ccr Caulobacter ... 1271 0.0 STM2481 [V] COG0841 Cation/multidrug efflux pump Sty Salmonella ... 1270 0.0 acrD [V] COG0841 Cation/multidrug efflux pump Eco Escherichia co... 1266 0.0 ZacrD [V] COG0841 Cation/multidrug efflux pump EcZ Escherichia c... 1264 0.0 STM0475 [V] COG0841 Cation/multidrug efflux pump Sty Salmonella ... 1262 0.0 PA0426 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas ... 1262 0.0 acrF [V] COG0841 Cation/multidrug efflux pump Eco Escherichia co... 1262 0.0 ECs3332 [V] COG0841 Cation/multidrug efflux pump Ecs Escherichia... 1262 0.0 >STM3391 [V] COG0841 Cation/multidrug efflux pump Sty Salmonella typhimurium LT2 Length = 1037 Score = 1275 bits (3299), Expect = 0.0, Method: Compositional matrix adjust. Identities = 624/1020 (61%), Positives = 775/1020 (75%), Gaps = 6/1020 (0%) Query: 1 MARFFIDRPIFAWVIAIIIMLGGMMSIRSLSLEQYPDIAPPKVNIKATYTGASAKTLEDS 60 MA FFI RPIFAWV+AII+M+ G ++I L + QYP IAPP V+I ATY GA A+T++D+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAIMQLPVAQYPTIAPPAVSISATYPGADAQTVQDT 60 Query: 61 VTQVIEQQMKGLDNLQYMSASSSSAGSATVSLTFTAGTNPDVAQMQVQNKLQQVTARLPQ 120 VTQVIEQ M G+DNL YMS++S SAGS T++LTF +GT+PD+AQ+QVQNKLQ T LPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 AVQNNGVTVTKASTDILMVLSLTSDDPRITSIDIGDFISSTLTDQISRVEGVGDVTAFGT 180 VQ G++V K+S+ LMV SD+P T DI D+++S + D ISR+ GVGDV FG Sbjct: 121 EVQQQGISVEKSSSSFLMVAGFVSDNPNTTQDDISDYVASNIKDSISRLNGVGDVQLFGA 180 Query: 181 NYAMRIWIDPAKLQKYALMPSDITSALQAQNTEVSAGEIGALPAQPGQQINATITARSKL 240 YAMRIW+D L KY L P D+ + L+ QN +++AG++G PA PGQQ+NA+I A+++L Sbjct: 181 QYAMRIWLDANLLNKYQLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRL 240 Query: 241 TTPDEFRNIIVKSSADGSVVKLSDVARVELGGESYQVASQQNGKPSSALAIQLATGANAL 300 P+EF + ++ + DGSVV L DVAR+ELGGE+Y V ++ NGKP+S L I+LATGANAL Sbjct: 241 KDPEEFGKVTLRVNTDGSVVHLKDVARIELGGENYNVVARINGKPASGLGIKLATGANAL 300 Query: 301 ATADAVKKKLAELEPYFPASMKLKTNIAYDTTPFVRVSLEEVVKTLIEAIVLVVLIMYLF 360 TA A+K KLAEL+P+FP MK+ YDTTPFV++S+ EVVKTL EAI+LV L+MYLF Sbjct: 301 DTATAIKVKLAELQPFFPQGMKVV--YPYDTTPFVKISIHEVVKTLFEAIILVFLVMYLF 358 Query: 361 LQNIRATFIPAITVPVVLLGTFGILAMFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 420 LQNIRAT IP I VPVVLLGTF +LA FGYSINTLTMFGMVLAIGLLVDDAIVVVENVER Sbjct: 359 LQNIRATLIPTIAVPVVLLGTFAVLAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 418 Query: 421 LMSEEKLSPKEATRKSMQEITGALVGIAMVLSAVFIPMAFFGGSTGVIYRQFSITIVSAM 480 +M E+ LSP+EAT KSM +I GALVGIAMVLSAVFIPMAFFGGSTG IYRQFSITIVSAM Sbjct: 419 VMMEDNLSPREATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAM 478 Query: 481 ALSVMVALTLTPALCATLLKP-HAGGHVQQGRFFTWFNRSFDRSATRYQGGVAGLLKRGK 539 ALSV+VAL LTPALCATLLKP A H ++ FF WFN FD S Y V+G+++ Sbjct: 479 ALSVLVALILTPALCATLLKPVSAEHHEKKSGFFGWFNTRFDHSVNHYTNSVSGIVRNTG 538 Query: 540 RGLLMYALIAVAMAVLFMRLPTSFLPEEDQGVLMAQIQLPTGATAEQTATVVKTVQEYFM 599 R L++Y LI V MAVLF+RLPTSFLPEEDQGV + IQLP+GAT E+T V+ V Y++ Sbjct: 539 RYLIIYLLIVVGMAVLFLRLPTSFLPEEDQGVFLTMIQLPSGATQERTQKVLDQVTHYYL 598 Query: 600 NKPE-SVESVLAIVGAGVGGNSQNGARAFIRLKDWEQRTGAGQSASELVRRANADLSKIR 658 N + +VESV + G G QN AF+ LK WE+R G S ++ RA S+IR Sbjct: 599 NNEKANVESVFTVNGFSFSGQGQNSGMAFVSLKPWEERNGEENSVEAVIARATRAFSQIR 658 Query: 659 GARVFLMNPPAVRGLGQSSGFDLELKDVGGVGHDALLQARDQFL-QLARSNALLANVRTT 717 VF N PA+ LG ++GFD EL D GG+GHDAL +AR+Q L +A+ LL VR Sbjct: 659 DGLVFPFNMPAIVELGTATGFDFELIDQGGLGHDALTKARNQLLGMVAKHPDLLVRVRPN 718 Query: 718 GLDDTPQLRVAIDDRKADALSIATSDINATLATAMGGTYVNDFLSNGRVKKVYVQGDSAF 777 GL+DTPQ ++ +D KA AL ++ SDIN T++ A+GG YVNDF+ GRVKKVYVQ D+ F Sbjct: 719 GLEDTPQFKLDVDQEKAQALGVSLSDINETISAALGGYYVNDFIDRGRVKKVYVQADAQF 778 Query: 778 RMQADDLNRWYVRNAASQMVPFAAFMSSQWTYGPSLLERYNGVSSFEIVGEPAAGVSSGT 837 RM D+N YVR+A +MVPF+ F S++W YG LERYNG+ S E++GE A G S+G Sbjct: 779 RMLPGDINNLYVRSANGEMVPFSTFSSARWIYGSPRLERYNGMPSMELLGEAAPGRSTGE 838 Query: 838 AMAEVEKLVAQLPAGIGFEWTGSSYQERLSGNQAPMLYAISILFVFLCLAALYESWSVPF 897 AM+ +E L +QLP GIG++WTG SYQERLSGNQAP LYAIS++ VFLCLAALYESWS+PF Sbjct: 839 AMSLMENLASQLPNGIGYDWTGMSYQERLSGNQAPALYAISLIVVFLCLAALYESWSIPF 898 Query: 898 AVILAVPLGIIGTVLLTGIFGMSNDVYFQVGLLTTVGLSAKNAILIVEFAKQLHE-SGKS 956 +V+L VPLG++G +L + G++NDVYFQVGLLTT+GLSAKNAILIVEFAK L E G+ Sbjct: 899 SVMLVVPLGVVGALLAASLRGLNNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMEKEGRG 958 Query: 957 LWEATLEAVQLRLRPILMTSLAFMFGVLPLAVASGAGSASRRAIGTGVLGGMLSATLLGI 1016 L EATLEA ++RLRPILMTSLAF+ GV+PL ++ GAGS ++ A+GTGV+GGML+ATLL I Sbjct: 959 LIEATLEASRMRLRPILMTSLAFILGVMPLVISRGAGSGAQNAVGTGVMGGMLTATLLAI 1018 >YPO3043 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pestis Length = 1043 Score = 1272 bits (3291), Expect = 0.0, Method: Compositional matrix adjust. Identities = 640/1028 (62%), Positives = 803/1028 (78%), Gaps = 4/1028 (0%) Query: 1 MARFFIDRPIFAWVIAIIIMLGGMMSIRSLSLEQYPDIAPPKVNIKATYTGASAKTLEDS 60 MA FFIDRPIFAWV+AII+ L G ++I +L +EQYP++APP V I A+Y GASA+TLE++ Sbjct: 1 MANFFIDRPIFAWVLAIILCLTGALAISTLPVEQYPNLAPPNVRISASYPGASAQTLENT 60 Query: 61 VTQVIEQQMKGLDNLQYMSASSSSAGSATVSLTFTAGTNPDVAQMQVQNKLQQVTARLPQ 120 VTQVIEQ M GLDNL YMS+ SS++GSA+V+LTF AGTNP+ A QVQN+LQ RLPQ Sbjct: 61 VTQVIEQSMTGLDNLLYMSSQSSNSGSASVTLTFQAGTNPNEAMQQVQNQLQSAIKRLPQ 120 Query: 121 AVQNNGVTVTKASTDILMVLSLTSDDPRITSIDIGDFISSTLTDQISRVEGVGDVTAFGT 180 VQ GV+V+K+ + LM+++ S D + DI D+++S L D +SR+EGVG V AFG+ Sbjct: 121 DVQQQGVSVSKSGDNTLMMVAFVSTDGSMDKQDISDYVASNLQDPLSRIEGVGSVDAFGS 180 Query: 181 NYAMRIWIDPAKLQKYALMPSDITSALQAQNTEVSAGEIGALPAQPGQQINATITARSKL 240 YAMRIW+DP KL Y L SDI SA+Q+QNT+V+ G++G PA Q +NATI A+S+L Sbjct: 181 QYAMRIWLDPNKLTNYQLTTSDIVSAIQSQNTQVAVGQLGGTPAVDNQALNATINAQSQL 240 Query: 241 TTPDEFRNIIVKSSADGSVVKLSDVARVELGGESYQVASQQNGKPSSALAIQLATGANAL 300 TP+EFR I ++ + DGS+V L DVA++ELG E Y S+ NG+ +S + I+LA+GAN L Sbjct: 241 QTPEEFREITLRVNQDGSLVTLGDVAKIELGSEKYDYLSRFNGQAASGMGIKLASGANEL 300 Query: 301 ATADAVKKKLAELEPYFPASMKLKTNIAYDTTPFVRVSLEEVVKTLIEAIVLVVLIMYLF 360 T VK +LAEL P+FP ++ K IAY+TTPFV+ S+++VVKTL+EAI+LV L+MYLF Sbjct: 301 QTDKRVKARLAELAPFFPHGLEAK--IAYETTPFVQASIKDVVKTLLEAILLVFLVMYLF 358 Query: 361 LQNIRATFIPAITVPVVLLGTFGILAMFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 420 LQN RAT IP + VPVVLLGTF +L+ FG+SINTLTMF +VLAIGLLVDDAIVVVENVER Sbjct: 359 LQNFRATLIPTVAVPVVLLGTFAVLSAFGFSINTLTMFAIVLAIGLLVDDAIVVVENVER 418 Query: 421 LMSEEKLSPKEATRKSMQEITGALVGIAMVLSAVFIPMAFFGGSTGVIYRQFSITIVSAM 480 +MSEE L P+EATRKSM +I GAL+GIA+VLSAVFIPMAFFGG+TG IYRQFSITIVSAM Sbjct: 419 VMSEEGLDPREATRKSMGQIQGALIGIALVLSAVFIPMAFFGGTTGAIYRQFSITIVSAM 478 Query: 481 ALSVMVALTLTPALCATLLKPHAGGHVQQGR-FFTWFNRSFDRSATRYQGGVAGLLKRGK 539 LSV+VAL LTPA+CATLLKP A GH R FF WFNR FDR++ RY+ GVA +L Sbjct: 479 VLSVLVALILTPAMCATLLKPIAPGHHHAKRGFFGWFNRMFDRNSHRYERGVARVLHHSL 538 Query: 540 RGLLMYALIAVAMAVLFMRLPTSFLPEEDQGVLMAQIQLPTGATAEQTATVVKTVQEYFM 599 R +L+Y L+ +A+LF++LPTSFLP ED+GV MAQ+QLP G+T +QT VV+ V+ YF+ Sbjct: 539 RYMLLYLLLLGGLALLFLKLPTSFLPLEDRGVFMAQVQLPVGSTQQQTLKVVEKVENYFL 598 Query: 600 NKPES-VESVLAIVGAGVGGNSQNGARAFIRLKDWEQRTGAGQSASELVRRANADLSKIR 658 + ++ V SV A VG+G GGN QN AR FIRL DW+QRT + S+ ++ RA +LSKI Sbjct: 599 TEEKNNVLSVFATVGSGPGGNGQNVARLFIRLADWDQRTASTDSSFAIIERATKELSKIV 658 Query: 659 GARVFLMNPPAVRGLGQSSGFDLELKDVGGVGHDALLQARDQFLQLARSNALLANVRTTG 718 A+V + +PPA+ GLG SSGFD+EL+D GG GHD L+ AR+Q LQ+A L VR G Sbjct: 659 EAKVSVSSPPAISGLGGSSGFDMELQDHGGHGHDKLMVARNQLLQMASQEPALTRVRHNG 718 Query: 719 LDDTPQLRVAIDDRKADALSIATSDINATLATAMGGTYVNDFLSNGRVKKVYVQGDSAFR 778 LDD+PQL++ ID RKA AL ++ +DIN+TL TA G TYVNDF+ GRVKKVYVQ ++ R Sbjct: 719 LDDSPQLQIDIDQRKAQALGVSLNDINSTLKTAWGSTYVNDFVDRGRVKKVYVQSEATAR 778 Query: 779 MQADDLNRWYVRNAASQMVPFAAFMSSQWTYGPSLLERYNGVSSFEIVGEPAAGVSSGTA 838 M +D+N+WYVRN MVPF+AF +++W YG LERYNG S+ EIVGE A+GVS+GTA Sbjct: 779 MLPEDVNKWYVRNKNGGMVPFSAFSTTRWEYGSPRLERYNGYSALEIVGEAASGVSTGTA 838 Query: 839 MAEVEKLVAQLPAGIGFEWTGSSYQERLSGNQAPMLYAISILFVFLCLAALYESWSVPFA 898 M +EKLV+QLP G G EWTG SYQERLSG+QAP LYAIS+L VFLCLAALYESWS+PF+ Sbjct: 839 MDVMEKLVSQLPNGFGLEWTGMSYQERLSGSQAPALYAISLLVVFLCLAALYESWSIPFS 898 Query: 899 VILAVPLGIIGTVLLTGIFGMSNDVYFQVGLLTTVGLSAKNAILIVEFAKQLHESGKSLW 958 V+L VPLG+IG V T + G+ NDVYFQVGLLT +GLSAKNAILIVEFA +L+ GK L Sbjct: 899 VMLVVPLGVIGAVAATWMRGLENDVYFQVGLLTIIGLSAKNAILIVEFANELNNRGKDLV 958 Query: 959 EATLEAVQLRLRPILMTSLAFMFGVLPLAVASGAGSASRRAIGTGVLGGMLSATLLGIFF 1018 EATLEA + RLRPILMTSLAF+FGVLP+A++ GAGS S+ A+GTGV+GGM+SAT+L IFF Sbjct: 959 EATLEASRQRLRPILMTSLAFIFGVLPMAISQGAGSGSQHAVGTGVMGGMISATVLAIFF 1018 Query: 1019 VPLFYYLI 1026 VPLF+ L+ Sbjct: 1019 VPLFFVLV 1026 >CC0807 [V] COG0841 Cation/multidrug efflux pump Ccr Caulobacter vibrioides Length = 1051 Score = 1271 bits (3290), Expect = 0.0, Method: Compositional matrix adjust. Identities = 635/1018 (62%), Positives = 798/1018 (78%), Gaps = 4/1018 (0%) Query: 1 MARFFIDRPIFAWVIAIIIMLGGMMSIRSLSLEQYPDIAPPKVNIKATYTGASAKTLEDS 60 ++RFFIDRPIFAWVIAI+IML G ++IR+L + QYP+IA P+V+I A Y GASAKT+EDS Sbjct: 2 LSRFFIDRPIFAWVIAIVIMLAGALAIRTLPIAQYPEIALPQVSISANYPGASAKTVEDS 61 Query: 61 VTQVIEQQMKGLDNLQYMSASSSSAGSATVSLTFTAGTNPDVAQMQVQNKLQQVTARLPQ 120 VTQVIEQ+MKGLD L YMS++S +GSATV+LTF AGT+ D+AQ+QVQNKLQ TA LPQ Sbjct: 62 VTQVIEQKMKGLDGLDYMSSTSDGSGSATVTLTFKAGTDIDIAQVQVQNKLQTATALLPQ 121 Query: 121 AVQNNGVTVTKASTDILMVLSLTSDDPRITSIDIGDFISSTLTDQISRVEGVGDVTAFGT 180 VQ G+TV K++ + +MV+ L S+DP+ T D+ D+++S L D +SRV+GVGD+ FG+ Sbjct: 122 EVQQQGLTVAKSARNFMMVIGLYSEDPKTTGADLADYMASNLQDPLSRVDGVGDIQLFGS 181 Query: 181 NYAMRIWIDPAKLQKYALMPSDITSALQAQNTEVSAGEIGALPAQPGQQINATITARSKL 240 YAMRIW+DP KL ++L P+D+ +A++AQN +VSAG+IG P PG +NATITA+S+L Sbjct: 182 QYAMRIWLDPQKLASFSLTPADVAAAIRAQNAQVSAGQIGGTPNLPGTGLNATITAQSRL 241 Query: 241 TTPDEFRNIIVKSSADGSVVKLSDVARVELGGESYQVASQQNGKPSSALAIQLATGANAL 300 TP++FR IIVK+++ G+ V+LSDVARVELG ESY ++ NG ++ +AI+LA GANAL Sbjct: 242 QTPEQFRQIIVKNTSGGATVRLSDVARVELGAESYASIAKFNGYQAAGMAIKLAPGANAL 301 Query: 301 ATADAVKKKLAELEPYFPASMKLKTNIAYDTTPFVRVSLEEVVKTLIEAIVLVVLIMYLF 360 TA AV ++A+LE FPA+ K I YD+TPFV++S+EEVVKTL+EAI+LV ++M+LF Sbjct: 302 DTAAAVNARMAQLEKNFPANYKYV--IPYDSTPFVKLSIEEVVKTLVEAIILVFIVMFLF 359 Query: 361 LQNIRATFIPAITVPVVLLGTFGILAMFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 420 LQN RAT IP I VPVVLLGTFG+LA FGYSINTLTMFG+VLAIGLLVDDAIVVVENVER Sbjct: 360 LQNWRATLIPTIAVPVVLLGTFGVLAAFGYSINTLTMFGLVLAIGLLVDDAIVVVENVER 419 Query: 421 LMSEEKLSPKEATRKSMQEITGALVGIAMVLSAVFIPMAFFGGSTGVIYRQFSITIVSAM 480 +MSEE LSPKEATRKSM EITGAL+GIA+VL+AVF+PMAFFGGS GVIYRQFSITIVSAM Sbjct: 420 VMSEEGLSPKEATRKSMNEITGALIGIALVLAAVFVPMAFFGGSQGVIYRQFSITIVSAM 479 Query: 481 ALSVMVALTLTPALCATLLKP-HAGGHVQQGRFFTWFNRSFDRSATRYQGGVAGLLKRGK 539 ALSV+VAL LTPAL AT+LKP AG H ++ FF WFNRSF+ ++RYQG V +L + Sbjct: 480 ALSVVVALVLTPALTATMLKPVKAGHHEEKTGFFGWFNRSFNDMSSRYQGSVRKILGKRG 539 Query: 540 RGLLMYALIAVAMAVLFMRLPTSFLPEEDQGVLMAQIQLPTGATAEQTATVVKTVQEYFM 599 R + +YA I VAM +LF+RLP++FLPEEDQG + +QLP GAT E+T V+ V+++F+ Sbjct: 540 RWMAIYAAIIVAMGLLFVRLPSAFLPEEDQGTMFTLVQLPAGATEEKTLAVLDQVRDHFL 599 Query: 600 -NKPESVESVLAIVGAGVGGNSQNGARAFIRLKDWEQRTGAGQSASELVRRANADLSKIR 658 + E+V+SV + G G QN AF+RLKD+E R A A + RA S+ R Sbjct: 600 VGEKEAVQSVFTVSGFSFAGAGQNAGLAFVRLKDFEHRKSANLKAQAVAGRAMGAFSQFR 659 Query: 659 GARVFLMNPPAVRGLGQSSGFDLELKDVGGVGHDALLQARDQFLQLARSNALLANVRTTG 718 A VF + PPAV+ LG SSGFD +L+DVGGVGH+AL+ AR+ L +A + L VR G Sbjct: 660 DAMVFAIVPPAVQELGNSSGFDFQLQDVGGVGHEALMNARNMMLGMASQDPSLVGVRPNG 719 Query: 719 LDDTPQLRVAIDDRKADALSIATSDINATLATAMGGTYVNDFLSNGRVKKVYVQGDSAFR 778 DDTPQL++ +D KA AL + T+DIN+ L+ A GG+YVNDF+ GRVKKVY+Q D+ FR Sbjct: 720 QDDTPQLKIEVDQAKAGALGLTTADINSALSAAWGGSYVNDFIDRGRVKKVYMQADAPFR 779 Query: 779 MQADDLNRWYVRNAASQMVPFAAFMSSQWTYGPSLLERYNGVSSFEIVGEPAAGVSSGTA 838 M +DLNRWYVRN QMV F AF ++ WTYG LERYNG+SS I G PA G SSG A Sbjct: 780 MTPEDLNRWYVRNNQGQMVAFPAFATASWTYGSPRLERYNGLSSVNIQGAPAPGKSSGDA 839 Query: 839 MAEVEKLVAQLPAGIGFEWTGSSYQERLSGNQAPMLYAISILFVFLCLAALYESWSVPFA 898 +A +EK+ A+LP G+G+EWTG S QE +GNQAP LYAISIL VFL LAALYESWS+P A Sbjct: 840 IAAMEKIAAKLPPGVGYEWTGLSAQELEAGNQAPALYAISILVVFLLLAALYESWSIPLA 899 Query: 899 VILAVPLGIIGTVLLTGIFGMSNDVYFQVGLLTTVGLSAKNAILIVEFAKQLHESGKSLW 958 VI+ +PLG+IG +L T G+SND+YFQVGLLTT+GL+AKNAILIVEFAK L+E G L Sbjct: 900 VIMVIPLGVIGALLATFARGLSNDIYFQVGLLTTMGLAAKNAILIVEFAKDLYEKGMGLI 959 Query: 959 EATLEAVQLRLRPILMTSLAFMFGVLPLAVASGAGSASRRAIGTGVLGGMLSATLLGI 1016 EATLEAV+LRLRPI+MTSLAF+FGVLPLA+++GAGS ++ AIGTGV+GGM+SATLL I Sbjct: 960 EATLEAVRLRLRPIIMTSLAFVFGVLPLAISNGAGSGAQHAIGTGVIGGMISATLLAI 1017 >STM2481 [V] COG0841 Cation/multidrug efflux pump Sty Salmonella typhimurium LT2 Length = 1037 Score = 1270 bits (3287), Expect = 0.0, Method: Compositional matrix adjust. Identities = 625/1041 (60%), Positives = 784/1041 (75%), Gaps = 8/1041 (0%) Query: 1 MARFFIDRPIFAWVIAIIIMLGGMMSIRSLSLEQYPDIAPPKVNIKATYTGASAKTLEDS 60 MA FFIDRPIFAWV+AI++ L G ++I SL +EQYPD+APP V I A Y GASA+TLE++ Sbjct: 1 MANFFIDRPIFAWVLAILLCLTGALAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENT 60 Query: 61 VTQVIEQQMKGLDNLQYMSASSSSAGSATVSLTFTAGTNPDVAQMQVQNKLQQVTARLPQ 120 VTQVIEQ M GLDNL YMS+ SS G AT++L+F AGT+PD A QVQN+LQ +LPQ Sbjct: 61 VTQVIEQNMTGLDNLMYMSSQSSGTGQATITLSFIAGTDPDEAVQQVQNQLQSAMRKLPQ 120 Query: 121 AVQNNGVTVTKASTDILMVLSLTSDDPRITSIDIGDFISSTLTDQISRVEGVGDVTAFGT 180 AVQ+ GVTV K ++ ++ S D + DI D+++S + D +SRV GVGD+ A+G+ Sbjct: 121 AVQDQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVASNIQDPLSRVNGVGDIDAYGS 180 Query: 181 NYAMRIWIDPAKLQKYALMPSDITSALQAQNTEVSAGEIGALPAQPGQQINATITARSKL 240 Y+MRIW+DPAKL + + D+T A+++QN +++ G++G P+ Q +NATI A+S L Sbjct: 181 QYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSLL 240 Query: 241 TTPDEFRNIIVKSSADGSVVKLSDVARVELGGESYQVASQQNGKPSSALAIQLATGANAL 300 TP +FR+I ++ + DGS VKL DVA VELG E Y S+ NG P+S L ++LA+GAN + Sbjct: 241 QTPQQFRDITLRVNQDGSEVKLGDVATVELGAEKYDYLSRFNGNPASGLGVKLASGANEM 300 Query: 301 ATADAVKKKLAELEPYFPASMKLKTNIAYDTTPFVRVSLEEVVKTLIEAIVLVVLIMYLF 360 ATA V +L EL YFP ++ K IAY+TT FV+ S+ +VVKTL+EAI LV L+MYLF Sbjct: 301 ATAKLVLDRLNELAQYFPHGLEYK--IAYETTSFVKASIIDVVKTLLEAIALVFLVMYLF 358 Query: 361 LQNIRATFIPAITVPVVLLGTFGILAMFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 420 LQN RAT IP I VPVVL+GTF +L FGYSINTLTMF MVLAIGLLVDDAIVVVENVER Sbjct: 359 LQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVLAIGLLVDDAIVVVENVER 418 Query: 421 LMSEEKLSPKEATRKSMQEITGALVGIAMVLSAVFIPMAFFGGSTGVIYRQFSITIVSAM 480 +MSEE L+P+EATRKSM +I GALVGIAMVLSAVF+PMAFFGG+TG IYRQFSITIVSAM Sbjct: 419 IMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAM 478 Query: 481 ALSVMVALTLTPALCATLLKP-HAGGHVQQGRFFTWFNRSFDRSATRYQGGVAGLLKRGK 539 LSV+VA+ LTPALCATLLKP H G Q FF WFNR+F+R+A RY+ GVA +L R Sbjct: 479 VLSVLVAMILTPALCATLLKPLHKGEQHGQRGFFGWFNRTFNRNAERYEKGVAKILHRSL 538 Query: 540 RGLLMYALIAVAMAVLFMRLPTSFLPEEDQGVLMAQIQLPTGATAEQTATVVKTVQEY-F 598 R +L+Y L+ M LF+RLPTSFLP+ED+G+ IQLP+G+T +QT VV+ V+ Y F Sbjct: 539 RWILIYVLLLGGMVFLFLRLPTSFLPQEDRGMFTTSIQLPSGSTQQQTLKVVEKVENYYF 598 Query: 599 MNKPESVESVLAIVGAGVGGNSQNGARAFIRLKDWEQRTGAGQSASELVRRANADLSKIR 658 ++ +++ SV + VG+G GGN QN AR F+RLKDW+ R S+ ++ RA ++I+ Sbjct: 599 THEKDNIMSVFSTVGSGPGGNGQNVARMFVRLKDWDARDPTTGSSFAIIERATKAFNQIK 658 Query: 659 GARVFLMNPPAVRGLGQSSGFDLELKDVGGVGHDALLQARDQFLQLARSNALLANVRTTG 718 ARVF +PPA+ GLG S+GFD+EL+D G GHDAL+ ARDQ ++LA N+ L VR G Sbjct: 659 EARVFASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARDQLIELAGKNSSLTRVRHNG 718 Query: 719 LDDTPQLRVAIDDRKADALSIATSDINATLATAMGGTYVNDFLSNGRVKKVYVQGDSAFR 778 LDD+PQL++ ID RKA AL ++ DIN TL TA G +YVNDF+ GRVKKVYVQ + +R Sbjct: 719 LDDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAKYR 778 Query: 779 MQADDLNRWYVRNAASQMVPFAAFMSSQWTYGPSLLERYNGVSSFEIVGEPAAGVSSGTA 838 M DD+N WYVRN MVPF+AF +S+W G LERYNG S+ EIVGE A GVS+GTA Sbjct: 779 MLPDDINLWYVRNKDGGMVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTA 838 Query: 839 MAEVEKLVAQLPAGIGFEWTGSSYQERLSGNQAPMLYAISILFVFLCLAALYESWSVPFA 898 M +E LV QLP G G EWT SYQERLSG QAP LYAIS+L VFLCLAALYESWSVPF+ Sbjct: 839 MDVMESLVHQLPGGFGLEWTAMSYQERLSGAQAPALYAISLLVVFLCLAALYESWSVPFS 898 Query: 899 VILAVPLGIIGTVLLTGIFGMSNDVYFQVGLLTTVGLSAKNAILIVEFAKQLHESGKSLW 958 V+L VPLG+IG +L T + G+ NDVYFQVGLLT +GLSAKNAILIVEFA ++++ G +L Sbjct: 899 VMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHALL 958 Query: 959 EATLEAVQLRLRPILMTSLAFMFGVLPLAVASGAGSASRRAIGTGVLGGMLSATLLGIFF 1018 +ATL A + RLRPILMTSLAF+FGVLP+A ++GAGS S+ A+GTGV+GGM+SAT+L IFF Sbjct: 959 DATLYASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGGMISATVLAIFF 1018 Query: 1019 VPLFYYLIGAWLDRRAAKKPR 1039 VPLF+ LI RR KPR Sbjct: 1019 VPLFFVLI----RRRFPLKPR 1035 >acrD [V] COG0841 Cation/multidrug efflux pump Eco Escherichia coli K12 Length = 1037 Score = 1266 bits (3275), Expect = 0.0, Method: Compositional matrix adjust. Identities = 617/1043 (59%), Positives = 784/1043 (75%), Gaps = 8/1043 (0%) Query: 1 MARFFIDRPIFAWVIAIIIMLGGMMSIRSLSLEQYPDIAPPKVNIKATYTGASAKTLEDS 60 MA FFIDRPIFAWV+AI++ L G ++I SL +EQYPD+APP V + A Y GASA+TLE++ Sbjct: 1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRVTANYPGASAQTLENT 60 Query: 61 VTQVIEQQMKGLDNLQYMSASSSSAGSATVSLTFTAGTNPDVAQMQVQNKLQQVTARLPQ 120 VTQVIEQ M GLDNL YMS+ SS G A+V+L+F AGT+PD A QVQN+LQ +LPQ Sbjct: 61 VTQVIEQNMTGLDNLMYMSSQSSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQ 120 Query: 121 AVQNNGVTVTKASTDILMVLSLTSDDPRITSIDIGDFISSTLTDQISRVEGVGDVTAFGT 180 AVQN GVTV K ++ ++ S D + DI D+++S + D +SRV GVGD+ A+G+ Sbjct: 121 AVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVASNIQDPLSRVNGVGDIDAYGS 180 Query: 181 NYAMRIWIDPAKLQKYALMPSDITSALQAQNTEVSAGEIGALPAQPGQQINATITARSKL 240 Y+MRIW+DPAKL + + D+T A+++QN +++ G++G P+ Q +NATI A+S L Sbjct: 181 QYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSLL 240 Query: 241 TTPDEFRNIIVKSSADGSVVKLSDVARVELGGESYQVASQQNGKPSSALAIQLATGANAL 300 TP++FR+I ++ + DGS V+L DVA VE+G E Y S+ NGKP+S L ++LA+GAN + Sbjct: 241 QTPEQFRDITLRVNQDGSEVRLGDVATVEMGAEKYDYLSRFNGKPASGLGVKLASGANEM 300 Query: 301 ATADAVKKKLAELEPYFPASMKLKTNIAYDTTPFVRVSLEEVVKTLIEAIVLVVLIMYLF 360 ATA+ V +L EL YFP ++ K +AY+TT FV+ S+E+VVKTL+EAI LV L+MYLF Sbjct: 301 ATAELVLNRLDELAQYFPHGLEYK--VAYETTSFVKASIEDVVKTLLEAIALVFLVMYLF 358 Query: 361 LQNIRATFIPAITVPVVLLGTFGILAMFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 420 LQN RAT IP I VPVVL+GTF +L FGYS+NTLTMF MVLAIGLLVDDAIVVVENVER Sbjct: 359 LQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNTLTMFAMVLAIGLLVDDAIVVVENVER 418 Query: 421 LMSEEKLSPKEATRKSMQEITGALVGIAMVLSAVFIPMAFFGGSTGVIYRQFSITIVSAM 480 +MSEE L+P+EATRKSM +I GALVGIAMVLSAVF+PMAFFGG+TG IYRQFSITIV+AM Sbjct: 419 IMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVAAM 478 Query: 481 ALSVMVALTLTPALCATLLKP-HAGGHVQQGRFFTWFNRSFDRSATRYQGGVAGLLKRGK 539 LSV+VA+ LTPALCATLLKP G H Q FF WFN+ F+R+A RY+ GVA +L R Sbjct: 479 VLSVLVAMILTPALCATLLKPLKKGEHHGQKGFFAWFNQMFNRNAERYEKGVAKILHRSL 538 Query: 540 RGLLMYALIAVAMAVLFMRLPTSFLPEEDQGVLMAQIQLPTGATAEQTATVVKTVQEY-F 598 R +++Y L+ M LF+RLPTSFLP ED+G+ +QLP+G+T +QT VV+ +++Y F Sbjct: 539 RWIVIYVLLLGGMVFLFLRLPTSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEQIEKYYF 598 Query: 599 MNKPESVESVLAIVGAGVGGNSQNGARAFIRLKDWEQRTGAGQSASELVRRANADLSKIR 658 ++ +++ SV A VG+G GGN QN AR FIRLKDW +R ++ ++ RA ++I+ Sbjct: 599 THEKDNIMSVFATVGSGPGGNGQNVARMFIRLKDWSERDSKTGTSFAIIERATKAFNQIK 658 Query: 659 GARVFLMNPPAVRGLGQSSGFDLELKDVGGVGHDALLQARDQFLQLARSNALLANVRTTG 718 ARV +PPA+ GLG S+GFD+EL+D G GHDAL+ AR+Q L LA N L VR G Sbjct: 659 EARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAAENPELTRVRHNG 718 Query: 719 LDDTPQLRVAIDDRKADALSIATSDINATLATAMGGTYVNDFLSNGRVKKVYVQGDSAFR 778 LDD+PQL++ ID RKA AL +A DIN TL TA G +YVNDF+ GRVKKVYVQ + +R Sbjct: 719 LDDSPQLQIDIDQRKAQALGVAIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYR 778 Query: 779 MQADDLNRWYVRNAASQMVPFAAFMSSQWTYGPSLLERYNGVSSFEIVGEPAAGVSSGTA 838 M DD+N WYVRN MVPF+AF +S+W G LERYNG S+ EIVGE A GVS+GTA Sbjct: 779 MLPDDINLWYVRNKDGGMVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTA 838 Query: 839 MAEVEKLVAQLPAGIGFEWTGSSYQERLSGNQAPMLYAISILFVFLCLAALYESWSVPFA 898 M +E LV QLP G G EWT SYQERLSG QAP LYAIS+L VFLCLAALYESWSVPF+ Sbjct: 839 MDIMESLVKQLPNGFGLEWTAMSYQERLSGAQAPALYAISLLVVFLCLAALYESWSVPFS 898 Query: 899 VILAVPLGIIGTVLLTGIFGMSNDVYFQVGLLTTVGLSAKNAILIVEFAKQLHESGKSLW 958 V+L VPLG+IG +L T + G+ NDVYFQVGLLT +GLSAKNAILIVEFA ++++ G L+ Sbjct: 899 VMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLF 958 Query: 959 EATLEAVQLRLRPILMTSLAFMFGVLPLAVASGAGSASRRAIGTGVLGGMLSATLLGIFF 1018 EATL A + RLRPILMTSLAF+FGVLP+A ++GAGS + A+GTGV+GGM+SAT+L I+F Sbjct: 959 EATLHACRQRLRPILMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYF 1018 Query: 1019 VPLFYYLIGAWLDRRAAKKPRQD 1041 VPLF+ L+ RR KPR + Sbjct: 1019 VPLFFVLV----RRRFPLKPRPE 1037 >ZacrD [V] COG0841 Cation/multidrug efflux pump EcZ Escherichia coli O157:H7 EDL933 Length = 1037 Score = 1264 bits (3270), Expect = 0.0, Method: Compositional matrix adjust. Identities = 616/1043 (59%), Positives = 783/1043 (75%), Gaps = 8/1043 (0%) Query: 1 MARFFIDRPIFAWVIAIIIMLGGMMSIRSLSLEQYPDIAPPKVNIKATYTGASAKTLEDS 60 MA FFIDRPIFAWV+AI++ L G ++I SL +EQYPD+APP V + A Y GASA+TLE++ Sbjct: 1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRVTANYPGASAQTLENT 60 Query: 61 VTQVIEQQMKGLDNLQYMSASSSSAGSATVSLTFTAGTNPDVAQMQVQNKLQQVTARLPQ 120 VTQVIEQ M GLDNL YMS+ SS G A+V+L+F AGT+PD A QVQN+LQ +LPQ Sbjct: 61 VTQVIEQNMTGLDNLMYMSSQSSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQ 120 Query: 121 AVQNNGVTVTKASTDILMVLSLTSDDPRITSIDIGDFISSTLTDQISRVEGVGDVTAFGT 180 AVQN GVTV K ++ ++ S D + DI D+++S + D +SRV GVGD+ A+G+ Sbjct: 121 AVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVASNIQDPLSRVNGVGDIDAYGS 180 Query: 181 NYAMRIWIDPAKLQKYALMPSDITSALQAQNTEVSAGEIGALPAQPGQQINATITARSKL 240 Y+MRIW+DPAKL + + D+T A+++QN +++ G++G P+ Q +NATI A+S L Sbjct: 181 QYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSLL 240 Query: 241 TTPDEFRNIIVKSSADGSVVKLSDVARVELGGESYQVASQQNGKPSSALAIQLATGANAL 300 TP++FR+I ++ + DGS V+L DVA E+G E Y S+ NGKP+S L ++LA+GAN + Sbjct: 241 QTPEQFRDITLRVNQDGSEVRLGDVATAEMGAEKYDYLSRFNGKPASGLGVKLASGANEM 300 Query: 301 ATADAVKKKLAELEPYFPASMKLKTNIAYDTTPFVRVSLEEVVKTLIEAIVLVVLIMYLF 360 ATA+ V +L EL YFP ++ K +AY+TT FV+ S+E+VVKTL+EAI LV L+MYLF Sbjct: 301 ATAELVLNRLDELAQYFPHGLEYK--VAYETTSFVKASIEDVVKTLLEAIALVFLVMYLF 358 Query: 361 LQNIRATFIPAITVPVVLLGTFGILAMFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 420 LQN RAT IP I VPVVL+GTF +L FGYS+NTLTMF MVLAIGLLVDDAIVVVENVER Sbjct: 359 LQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNTLTMFAMVLAIGLLVDDAIVVVENVER 418 Query: 421 LMSEEKLSPKEATRKSMQEITGALVGIAMVLSAVFIPMAFFGGSTGVIYRQFSITIVSAM 480 +MSEE L+P+EATRKSM +I GALVGIAMVLSAVF+PMAFFGG+TG IYRQFSITIV+AM Sbjct: 419 IMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVAAM 478 Query: 481 ALSVMVALTLTPALCATLLKP-HAGGHVQQGRFFTWFNRSFDRSATRYQGGVAGLLKRGK 539 LSV+VA+ LTPALCATLLKP G H Q FF WFN+ F+R+A RY+ GVA +L R Sbjct: 479 VLSVLVAMILTPALCATLLKPLKKGEHHGQKGFFAWFNQMFNRNAERYEKGVAKILHRSL 538 Query: 540 RGLLMYALIAVAMAVLFMRLPTSFLPEEDQGVLMAQIQLPTGATAEQTATVVKTVQEY-F 598 R +++Y L+ M LF+RLPTSFLP ED+G+ +QLP+G+T +QT VV+ +++Y F Sbjct: 539 RWIVIYVLLLGGMVFLFLRLPTSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEQIEKYYF 598 Query: 599 MNKPESVESVLAIVGAGVGGNSQNGARAFIRLKDWEQRTGAGQSASELVRRANADLSKIR 658 ++ +++ SV A VG+G GGN QN AR FIRLKDW +R ++ ++ RA ++I+ Sbjct: 599 THEKDNIMSVFATVGSGPGGNGQNVARMFIRLKDWSERDSKTGTSFAIIERATKAFNQIK 658 Query: 659 GARVFLMNPPAVRGLGQSSGFDLELKDVGGVGHDALLQARDQFLQLARSNALLANVRTTG 718 ARV +PPA+ GLG S+GFD+EL+D G GHDAL+ AR+Q L LA N L VR G Sbjct: 659 EARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAAENPELTRVRHNG 718 Query: 719 LDDTPQLRVAIDDRKADALSIATSDINATLATAMGGTYVNDFLSNGRVKKVYVQGDSAFR 778 LDD+PQL++ ID RKA AL +A DIN TL TA G +YVNDF+ GRVKKVYVQ + +R Sbjct: 719 LDDSPQLQIDIDQRKAQALGVAIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYR 778 Query: 779 MQADDLNRWYVRNAASQMVPFAAFMSSQWTYGPSLLERYNGVSSFEIVGEPAAGVSSGTA 838 M DD+N WYVRN MVPF+AF +S+W G LERYNG S+ EIVGE A GVS+GTA Sbjct: 779 MLPDDINLWYVRNKDGGMVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTA 838 Query: 839 MAEVEKLVAQLPAGIGFEWTGSSYQERLSGNQAPMLYAISILFVFLCLAALYESWSVPFA 898 M +E LV QLP G G EWT SYQERLSG QAP LYAIS+L VFLCLAALYESWSVPF+ Sbjct: 839 MDIMESLVKQLPNGFGLEWTAMSYQERLSGAQAPALYAISLLVVFLCLAALYESWSVPFS 898 Query: 899 VILAVPLGIIGTVLLTGIFGMSNDVYFQVGLLTTVGLSAKNAILIVEFAKQLHESGKSLW 958 V+L VPLG+IG +L T + G+ NDVYFQVGLLT +GLSAKNAILIVEFA ++++ G L+ Sbjct: 899 VMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLF 958 Query: 959 EATLEAVQLRLRPILMTSLAFMFGVLPLAVASGAGSASRRAIGTGVLGGMLSATLLGIFF 1018 EATL A + RLRPILMTSLAF+FGVLP+A ++GAGS + A+GTGV+GGM+SAT+L I+F Sbjct: 959 EATLHACRQRLRPILMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYF 1018 Query: 1019 VPLFYYLIGAWLDRRAAKKPRQD 1041 VPLF+ L+ RR KPR + Sbjct: 1019 VPLFFVLV----RRRFPLKPRPE 1037 >STM0475 [V] COG0841 Cation/multidrug efflux pump Sty Salmonella typhimurium LT2 Length = 1049 Score = 1262 bits (3266), Expect = 0.0, Method: Compositional matrix adjust. Identities = 621/1021 (60%), Positives = 780/1021 (76%), Gaps = 7/1021 (0%) Query: 1 MARFFIDRPIFAWVIAIIIMLGGMMSIRSLSLEQYPDIAPPKVNIKATYTGASAKTLEDS 60 M FFIDRPIFAWVIAIIIML G ++I L + QYP IAPP V I ATY GA AKT++D+ Sbjct: 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISATYPGADAKTVQDT 60 Query: 61 VTQVIEQQMKGLDNLQYMSASSSSAGSATVSLTFTAGTNPDVAQMQVQNKLQQVTARLPQ 120 VTQVIEQ M G+DNL YMS++S S G+ ++LTF +GT+ D+AQ+QVQNKLQ LPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQ 120 Query: 121 AVQNNGVTVTKASTDILMVLSLTSDDPRITSIDIGDFISSTLTDQISRVEGVGDVTAFGT 180 VQ GV+V K+S+ LMV+ + + D +T DI D++++ + D ISR GVGDV FG+ Sbjct: 121 EVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDPISRTSGVGDVQLFGS 180 Query: 181 NYAMRIWIDPAKLQKYALMPSDITSALQAQNTEVSAGEIGALPAQPGQQINATITARSKL 240 YAMRIW++P +L KY L P D+ +A++AQN +V+AG++G P GQQ+NA+I A+++L Sbjct: 181 QYAMRIWMNPTELTKYQLTPVDVINAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240 Query: 241 TTPDEFRNIIVKSSADGSVVKLSDVARVELGGESYQVASQQNGKPSSALAIQLATGANAL 300 T+ DEF I++K + DGS V+L DVA++ELGGE+Y V ++ NG+P+S L I+LATGANAL Sbjct: 241 TSTDEFGKILLKVNQDGSQVRLRDVAKIELGGENYDVIAKFNGQPASGLGIKLATGANAL 300 Query: 301 ATADAVKKKLAELEPYFPASMKLKTNIAYDTTPFVRVSLEEVVKTLIEAIVLVVLIMYLF 360 TA A++ +L ++EP+FP MK+ YDTTPFV++S+ EVVKTL+EAI+LV L+MYLF Sbjct: 301 DTATAIRAELKKMEPFFPPGMKIV--YPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLF 358 Query: 361 LQNIRATFIPAITVPVVLLGTFGILAMFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 420 LQN RAT IP I VPVVLLGTF +LA FG+SINTLTMFGMVLAIGLLVDDAIVVVENVER Sbjct: 359 LQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVER 418 Query: 421 LMSEEKLSPKEATRKSMQEITGALVGIAMVLSAVFIPMAFFGGSTGVIYRQFSITIVSAM 480 +M+EE L PKEATRKSM +I GALVGIAMVLSAVFIPMAFFGGSTG IYRQFSITIVSAM Sbjct: 419 VMTEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAM 478 Query: 481 ALSVMVALTLTPALCATLLKPHAGGHVQQGR--FFTWFNRSFDRSATRYQGGVAGLLKRG 538 ALSV+VAL LTPALCAT+LKP A G +G+ FF WFNR FD+S Y V +L+ Sbjct: 479 ALSVLVALILTPALCATMLKPVAKGDHGEGKKGFFGWFNRLFDKSTHHYTDSVGNILRST 538 Query: 539 KRGLLMYALIAVAMAVLFMRLPTSFLPEEDQGVLMAQIQLPTGATAEQTATVVKTVQEYF 598 R LL+Y +I V MA LF+RLP+SFLP+EDQGV + +QLP GAT E+T V+ V +Y+ Sbjct: 539 GRYLLLYLIIVVGMAYLFVRLPSSFLPDEDQGVFLTMVQLPAGATQERTQKVLDEVTDYY 598 Query: 599 MNKPE-SVESVLAIVGAGVGGNSQNGARAFIRLKDWEQRTGAGQSASELVRRANADLSKI 657 +NK + +VESV A+ G G G QN AF+ LKDW R G + +RA A S+I Sbjct: 599 LNKEKANVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEKNKVEAITQRATAAFSQI 658 Query: 658 RGARVFLMNPPAVRGLGQSSGFDLELKDVGGVGHDALLQARDQ-FLQLARSNALLANVRT 716 + A VF N PA+ LG ++GFD EL D G+GH+ L QAR+Q F ++A+ LL VR Sbjct: 659 KDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLFGEVAKYPDLLVGVRP 718 Query: 717 TGLDDTPQLRVAIDDRKADALSIATSDINATLATAMGGTYVNDFLSNGRVKKVYVQGDSA 776 GL+DTPQ ++ ID KA AL ++ SDIN TL A GG+YVNDF+ GRVKKVYV ++ Sbjct: 719 NGLEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAK 778 Query: 777 FRMQADDLNRWYVRNAASQMVPFAAFMSSQWTYGPSLLERYNGVSSFEIVGEPAAGVSSG 836 +RM DD+N WYVR + QMVPF+AF SS+W YG LERYNG+ S EI+G+ A G S+G Sbjct: 779 YRMLPDDINDWYVRGSDGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTG 838 Query: 837 TAMAEVEKLVAQLPAGIGFEWTGSSYQERLSGNQAPMLYAISILFVFLCLAALYESWSVP 896 AMA +E+L ++LP+GIG++WTG SYQERLSGNQAP LYAIS++ VFLCLAALYESWS+P Sbjct: 839 EAMAMMEELASKLPSGIGYDWTGMSYQERLSGNQAPALYAISLIVVFLCLAALYESWSIP 898 Query: 897 FAVILAVPLGIIGTVLLTGIFGMSNDVYFQVGLLTTVGLSAKNAILIVEFAKQL-HESGK 955 F+V+L VPLG+IG +L G++NDVYFQVGLLTT+GLSAKNAILIVEFAK L + GK Sbjct: 899 FSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGK 958 Query: 956 SLWEATLEAVQLRLRPILMTSLAFMFGVLPLAVASGAGSASRRAIGTGVLGGMLSATLLG 1015 L EATLEAV++RLRPILMTSLAFM GV+PL ++SGAGS ++ A+GTGVLGGM++AT+L Sbjct: 959 GLVEATLEAVRMRLRPILMTSLAFMLGVMPLVISSGAGSGAQNAVGTGVLGGMVTATVLA 1018 Query: 1016 I 1016 I Sbjct: 1019 I 1019 >PA0426 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas aeruginosa Length = 1046 Score = 1262 bits (3266), Expect = 0.0, Method: Compositional matrix adjust. Identities = 617/1040 (59%), Positives = 786/1040 (75%), Gaps = 5/1040 (0%) Query: 1 MARFFIDRPIFAWVIAIIIMLGGMMSIRSLSLEQYPDIAPPKVNIKATYTGASAKTLEDS 60 M++FFIDRPIFAWVIA++IML G +SI SL + QYP IAPP + ++ +Y GASA+T++D+ Sbjct: 1 MSKFFIDRPIFAWVIALVIMLAGGLSILSLPVNQYPAIAPPAIAVQVSYPGASAETVQDT 60 Query: 61 VTQVIEQQMKGLDNLQYMSASSSSAGSATVSLTFTAGTNPDVAQMQVQNKLQQVTARLPQ 120 V QVIEQQM G+DNL+Y+S+ S+S GS T+++TF GT+PD+AQ+QVQNKLQ T LPQ Sbjct: 61 VVQVIEQQMNGIDNLRYISSESNSDGSMTITVTFEQGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 AVQNNGVTVTKASTDILMVLSLTSDDPRITSIDIGDFISSTLTDQISRVEGVGDVTAFGT 180 VQ G+ VTKA + LMV+ + S D +T D+ ++I S + D +SR +GVGD FG+ Sbjct: 121 EVQRQGIRVTKAVKNFLMVVGVVSTDGSMTKEDLSNYIVSNIQDPLSRTKGVGDFQVFGS 180 Query: 181 NYAMRIWIDPAKLQKYALMPSDITSALQAQNTEVSAGEIGALPAQPGQQINATITARSKL 240 Y+MRIW+DPAKL Y L P D++SA+QAQN ++S+G++G LPA GQQ+NATI +++L Sbjct: 181 QYSMRIWLDPAKLNSYQLTPGDVSSAIQAQNVQISSGQLGGLPAVKGQQLNATIIGKTRL 240 Query: 241 TTPDEFRNIIVKSSADGSVVKLSDVARVELGGESYQVASQQNGKPSSALAIQLATGANAL 300 T ++F NI++K + DGS V+L DVA V LGG+ Y + +Q NG P+S +AI+LATGANAL Sbjct: 241 QTAEQFENILLKVNPDGSQVRLKDVADVGLGGQDYSINAQFNGSPASGIAIKLATGANAL 300 Query: 301 ATADAVKKKLAELEPYFPASMKLKTNIAYDTTPFVRVSLEEVVKTLIEAIVLVVLIMYLF 360 TA A+++ +A LEP+ P MK+ YDTTP V S+ EVVKTL EAI+LV L+MYLF Sbjct: 301 DTAKAIRQTIANLEPFMPQGMKVV--YPYDTTPVVSASIHEVVKTLGEAILLVFLVMYLF 358 Query: 361 LQNIRATFIPAITVPVVLLGTFGILAMFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 420 LQN RAT IP I VPVVLLGTFG+LA FG+SINTLTMFGMVLAIGLLVDDAIVVVENVER Sbjct: 359 LQNFRATLIPTIAVPVVLLGTFGVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVER 418 Query: 421 LMSEEKLSPKEATRKSMQEITGALVGIAMVLSAVFIPMAFFGGSTGVIYRQFSITIVSAM 480 +M+EE LSP+EA RKSM +I GALVGIAMVLSAVF+PMAFFGGSTGVIYRQFSITIVSAM Sbjct: 419 VMAEEGLSPREAARKSMGQIQGALVGIAMVLSAVFLPMAFFGGSTGVIYRQFSITIVSAM 478 Query: 481 ALSVMVALTLTPALCATLLKP-HAGGH-VQQGRFFTWFNRSFDRSATRYQGGVAGLLKRG 538 ALSV+VAL LTPALCAT+LKP G H +G FF WFNR F + Y+ GVA +LK Sbjct: 479 ALSVIVALILTPALCATMLKPIEKGDHGEHKGGFFGWFNRMFLSTTHGYERGVASILKHR 538 Query: 539 KRGLLMYALIAVAMAVLFMRLPTSFLPEEDQGVLMAQIQLPTGATAEQTATVVKTVQEYF 598 LL+Y +I M +F R+PT+FLP+EDQGVL AQ+Q P G++AE+T VV +++EY Sbjct: 539 APYLLIYVVIVAGMIWMFTRIPTAFLPDEDQGVLFAQVQTPPGSSAERTQVVVDSMREYL 598 Query: 599 MNKPESVESV-LAIVGAGVGGNSQNGARAFIRLKDWEQRTGAGQSASELVRRANADLSKI 657 + K S S + G G Q+ AFI LK WE+R G S EL +RA Sbjct: 599 LEKESSSVSSVFTVTGFNFAGRGQSSGMAFIMLKPWEERPGGENSVFELAKRAQMHFFSF 658 Query: 658 RGARVFLMNPPAVRGLGQSSGFDLELKDVGGVGHDALLQARDQFLQLARSNALLANVRTT 717 + A VF PP+V LG ++GFDL L+D GVGH+ LLQAR++FL LA N L VR Sbjct: 659 KDAMVFAFAPPSVLELGNATGFDLFLQDQAGVGHEVLLQARNKFLMLAAQNPALQRVRPN 718 Query: 718 GLDDTPQLRVAIDDRKADALSIATSDINATLATAMGGTYVNDFLSNGRVKKVYVQGDSAF 777 G+ D PQ ++ IDD KA AL ++ +DIN+T++ A G +YVNDF+ GRVK+VY+QG Sbjct: 719 GMSDEPQYKLEIDDEKASALGVSLADINSTVSIAWGSSYVNDFIDRGRVKRVYLQGRPDA 778 Query: 778 RMQADDLNRWYVRNAASQMVPFAAFMSSQWTYGPSLLERYNGVSSFEIVGEPAAGVSSGT 837 RM DDL++WYVRN +MVPF AF + +W YG LERYNGV + EI+GEPA G+SSG Sbjct: 779 RMNPDDLSKWYVRNDKGEMVPFNAFATGKWEYGSPKLERYNGVPAMEILGEPAPGLSSGD 838 Query: 838 AMAEVEKLVAQLPAGIGFEWTGSSYQERLSGNQAPMLYAISILFVFLCLAALYESWSVPF 897 AMA VE++V QLP G+G+ WTG SY+ERLSG+QAP LYA+S+L VFLCLAALYESWS+PF Sbjct: 839 AMAAVEEIVKQLPKGVGYSWTGLSYEERLSGSQAPALYALSLLVVFLCLAALYESWSIPF 898 Query: 898 AVILAVPLGIIGTVLLTGIFGMSNDVYFQVGLLTTVGLSAKNAILIVEFAKQLHESGKSL 957 +V+L VPLG+IG +L T + G+SNDV+FQVGLLTT+GLSAKNAILIVEFAK+LHE GK + Sbjct: 899 SVMLVVPLGVIGALLATSMRGLSNDVFFQVGLLTTIGLSAKNAILIVEFAKELHEQGKGI 958 Query: 958 WEATLEAVQLRLRPILMTSLAFMFGVLPLAVASGAGSASRRAIGTGVLGGMLSATLLGIF 1017 EA +EA ++RLRPI+MTSLAF+ GV+PLA+++GAGS S+ AIGTGV+GGM++AT+L IF Sbjct: 959 VEAAIEACRMRLRPIVMTSLAFILGVVPLAISTGAGSGSQHAIGTGVIGGMVTATVLAIF 1018 Query: 1018 FVPLFYYLIGAWLDRRAAKK 1037 +VPLFY + A+K+ Sbjct: 1019 WVPLFYVAVSTLFKDEASKQ 1038 >acrF [V] COG0841 Cation/multidrug efflux pump Eco Escherichia coli K12 Length = 1034 Score = 1262 bits (3265), Expect = 0.0, Method: Compositional matrix adjust. Identities = 624/1020 (61%), Positives = 772/1020 (75%), Gaps = 6/1020 (0%) Query: 1 MARFFIDRPIFAWVIAIIIMLGGMMSIRSLSLEQYPDIAPPKVNIKATYTGASAKTLEDS 60 MA FFI RPIFAWV+AII+M+ G ++I L + QYP IAPP V++ A Y GA A+T++D+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQQMKGLDNLQYMSASSSSAGSATVSLTFTAGTNPDVAQMQVQNKLQQVTARLPQ 120 VTQVIEQ M G+DNL YMS++S SAGS T++LTF +GT+PD+AQ+QVQNKLQ T LPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 AVQNNGVTVTKASTDILMVLSLTSDDPRITSIDIGDFISSTLTDQISRVEGVGDVTAFGT 180 VQ G++V K+S+ LMV SD+P T DI D+++S + D +SR+ GVGDV FG Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 NYAMRIWIDPAKLQKYALMPSDITSALQAQNTEVSAGEIGALPAQPGQQINATITARSKL 240 YAMRIW+D L KY L P D+ + L+ QN +++AG++G PA PGQQ+NA+I A+++ Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 TTPDEFRNIIVKSSADGSVVKLSDVARVELGGESYQVASQQNGKPSSALAIQLATGANAL 300 P+EF + ++ ++DGSVV+L DVARVELGGE+Y V ++ NGKP++ L I+LATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 ATADAVKKKLAELEPYFPASMKLKTNIAYDTTPFVRVSLEEVVKTLIEAIVLVVLIMYLF 360 TA A+K KLAEL+P+FP MK+ YDTTPFV++S+ EVVKTL EAI+LV L+MYLF Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVL--YPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLF 358 Query: 361 LQNIRATFIPAITVPVVLLGTFGILAMFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 420 LQN+RAT IP I VPVVLLGTF ILA FGYSINTLTMFGMVLAIGLLVDDAIVVVENVER Sbjct: 359 LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 418 Query: 421 LMSEEKLSPKEATRKSMQEITGALVGIAMVLSAVFIPMAFFGGSTGVIYRQFSITIVSAM 480 +M E+KL PKEAT KSM +I GALVGIAMVLSAVFIPMAFFGGSTG IYRQFSITIVSAM Sbjct: 419 VMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAM 478 Query: 481 ALSVMVALTLTPALCATLLKP-HAGGHVQQGRFFTWFNRSFDRSATRYQGGVAGLLKRGK 539 ALSV+VAL LTPALCATLLKP A H +G FF WFN +FD S Y V +L Sbjct: 479 ALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTG 538 Query: 540 RGLLMYALIAVAMAVLFMRLPTSFLPEEDQGVLMAQIQLPTGATAEQTATVVKTVQEYFM 599 R LL+YALI M VLF+RLP+SFLPEEDQGV + IQLP GAT E+T V+ V +Y++ Sbjct: 539 RYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYL 598 Query: 600 -NKPESVESVLAIVGAGVGGNSQNGARAFIRLKDWEQRTGAGQSASELVRRANADLSKIR 658 N+ +VESV + G G +QN AF+ LK WE+R G SA ++ RA +L KIR Sbjct: 599 KNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIR 658 Query: 659 GARVFLMNPPAVRGLGQSSGFDLELKDVGGVGHDALLQARDQFLQLARSN-ALLANVRTT 717 V N PA+ LG ++GFD EL D G+GHDAL QAR+Q L +A + A L +VR Sbjct: 659 DGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPN 718 Query: 718 GLDDTPQLRVAIDDRKADALSIATSDINATLATAMGGTYVNDFLSNGRVKKVYVQGDSAF 777 GL+DT Q ++ +D KA AL ++ SDIN T++TA+GGTYVNDF+ GRVKK+YVQ D+ F Sbjct: 719 GLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKF 778 Query: 778 RMQADDLNRWYVRNAASQMVPFAAFMSSQWTYGPSLLERYNGVSSFEIVGEPAAGVSSGT 837 RM +D+++ YVR+A +MVPF+AF +S W YG LERYNG+ S EI GE A G SSG Sbjct: 779 RMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGD 838 Query: 838 AMAEVEKLVAQLPAGIGFEWTGSSYQERLSGNQAPMLYAISILFVFLCLAALYESWSVPF 897 AMA +E L ++LPAGIG++WTG SYQERLSGNQAP L AIS + VFLCLAALYESWS+P Sbjct: 839 AMALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPV 898 Query: 898 AVILAVPLGIIGTVLLTGIFGMSNDVYFQVGLLTTVGLSAKNAILIVEFAKQLHE-SGKS 956 +V+L VPLGI+G +L +F NDVYF VGLLTT+GLSAKNAILIVEFAK L E GK Sbjct: 899 SVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKG 958 Query: 957 LWEATLEAVQLRLRPILMTSLAFMFGVLPLAVASGAGSASRRAIGTGVLGGMLSATLLGI 1016 + EATL AV++RLRPILMTSLAF+ GVLPLA+++GAGS ++ A+G GV+GGM+SATLL I Sbjct: 959 VVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAI 1018 >ECs3332 [V] COG0841 Cation/multidrug efflux pump Ecs Escherichia coli O157:H7 Length = 1037 Score = 1262 bits (3265), Expect = 0.0, Method: Compositional matrix adjust. Identities = 615/1043 (58%), Positives = 783/1043 (75%), Gaps = 8/1043 (0%) Query: 1 MARFFIDRPIFAWVIAIIIMLGGMMSIRSLSLEQYPDIAPPKVNIKATYTGASAKTLEDS 60 MA FFIDRPIFAWV+AI++ L G ++I SL +EQYPD+APP V + A Y GASA+TLE++ Sbjct: 1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRVTANYPGASAQTLENT 60 Query: 61 VTQVIEQQMKGLDNLQYMSASSSSAGSATVSLTFTAGTNPDVAQMQVQNKLQQVTARLPQ 120 VTQVIEQ M GLDNL YMS+ SS G A+V+L+F AGT+PD A QVQN+LQ +LPQ Sbjct: 61 VTQVIEQNMTGLDNLMYMSSQSSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQ 120 Query: 121 AVQNNGVTVTKASTDILMVLSLTSDDPRITSIDIGDFISSTLTDQISRVEGVGDVTAFGT 180 AVQN G+TV K ++ ++ S D + DI D+++S + D +SRV GVGD+ A+G+ Sbjct: 121 AVQNQGLTVRKTGDTNILTIAFVSTDGSMDKQDIADYVASNIQDPLSRVNGVGDIDAYGS 180 Query: 181 NYAMRIWIDPAKLQKYALMPSDITSALQAQNTEVSAGEIGALPAQPGQQINATITARSKL 240 Y+MRIW+DPAKL + + D+T A+++QN +++ G++G P+ Q +NATI A+S L Sbjct: 181 QYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSLL 240 Query: 241 TTPDEFRNIIVKSSADGSVVKLSDVARVELGGESYQVASQQNGKPSSALAIQLATGANAL 300 TP++FR+I ++ + DGS V+L DVA E+G E Y S+ NGKP+S L ++LA+GAN + Sbjct: 241 QTPEQFRDITLRVNQDGSEVRLGDVATAEMGAEKYDYLSRFNGKPASGLGVKLASGANEM 300 Query: 301 ATADAVKKKLAELEPYFPASMKLKTNIAYDTTPFVRVSLEEVVKTLIEAIVLVVLIMYLF 360 ATA+ V +L EL YFP ++ K +AY+TT FV+ S+E+VVKTL+EAI LV L+MYLF Sbjct: 301 ATAELVLNRLDELAQYFPHGLEYK--VAYETTSFVKASIEDVVKTLLEAIALVFLVMYLF 358 Query: 361 LQNIRATFIPAITVPVVLLGTFGILAMFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 420 LQN RAT IP I VPVVL+GTF +L FGYS+NTLTMF MVLAIGLLVDDAIVVVENVER Sbjct: 359 LQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNTLTMFAMVLAIGLLVDDAIVVVENVER 418 Query: 421 LMSEEKLSPKEATRKSMQEITGALVGIAMVLSAVFIPMAFFGGSTGVIYRQFSITIVSAM 480 +MSEE L+P+EATRKSM +I GALVGIAMVLSAVF+PMAFFGG+TG IYRQFSITIV+AM Sbjct: 419 IMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVAAM 478 Query: 481 ALSVMVALTLTPALCATLLKP-HAGGHVQQGRFFTWFNRSFDRSATRYQGGVAGLLKRGK 539 LSV+VA+ LTPALCATLLKP G H Q FF WFN+ F+R+A RY+ GVA +L R Sbjct: 479 VLSVLVAMILTPALCATLLKPLKKGEHHGQKGFFAWFNQMFNRNAERYEKGVAKILHRSL 538 Query: 540 RGLLMYALIAVAMAVLFMRLPTSFLPEEDQGVLMAQIQLPTGATAEQTATVVKTVQEY-F 598 R +++Y L+ M LF+RLPTSFLP ED+G+ +QLP+G+T +QT VV+ +++Y F Sbjct: 539 RWIVIYVLLLGGMVFLFLRLPTSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEQIEKYYF 598 Query: 599 MNKPESVESVLAIVGAGVGGNSQNGARAFIRLKDWEQRTGAGQSASELVRRANADLSKIR 658 ++ +++ SV A VG+G GGN QN AR FIRLKDW +R ++ ++ RA ++I+ Sbjct: 599 THEKDNIMSVFATVGSGPGGNGQNVARMFIRLKDWSERDSKTGTSFAIIERATKAFNQIK 658 Query: 659 GARVFLMNPPAVRGLGQSSGFDLELKDVGGVGHDALLQARDQFLQLARSNALLANVRTTG 718 ARV +PPA+ GLG S+GFD+EL+D G GHDAL+ AR+Q L LA N L VR G Sbjct: 659 EARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAAENPELTRVRHNG 718 Query: 719 LDDTPQLRVAIDDRKADALSIATSDINATLATAMGGTYVNDFLSNGRVKKVYVQGDSAFR 778 LDD+PQL++ ID RKA AL +A DIN TL TA G +YVNDF+ GRVKKVYVQ + +R Sbjct: 719 LDDSPQLQIDIDQRKAQALGVAIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYR 778 Query: 779 MQADDLNRWYVRNAASQMVPFAAFMSSQWTYGPSLLERYNGVSSFEIVGEPAAGVSSGTA 838 M DD+N WYVRN MVPF+AF +S+W G LERYNG S+ EIVGE A GVS+GTA Sbjct: 779 MLPDDINLWYVRNKDGGMVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTA 838 Query: 839 MAEVEKLVAQLPAGIGFEWTGSSYQERLSGNQAPMLYAISILFVFLCLAALYESWSVPFA 898 M +E LV QLP G G EWT SYQERLSG QAP LYAIS+L VFLCLAALYESWSVPF+ Sbjct: 839 MDIMESLVKQLPNGFGLEWTAMSYQERLSGAQAPALYAISLLVVFLCLAALYESWSVPFS 898 Query: 899 VILAVPLGIIGTVLLTGIFGMSNDVYFQVGLLTTVGLSAKNAILIVEFAKQLHESGKSLW 958 V+L VPLG+IG +L T + G+ NDVYFQVGLLT +GLSAKNAILIVEFA ++++ G L+ Sbjct: 899 VMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLF 958 Query: 959 EATLEAVQLRLRPILMTSLAFMFGVLPLAVASGAGSASRRAIGTGVLGGMLSATLLGIFF 1018 EATL A + RLRPILMTSLAF+FGVLP+A ++GAGS + A+GTGV+GGM+SAT+L I+F Sbjct: 959 EATLHACRQRLRPILMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYF 1018 Query: 1019 VPLFYYLIGAWLDRRAAKKPRQD 1041 VPLF+ L+ RR KPR + Sbjct: 1019 VPLFFVLV----RRRFPLKPRPE 1037