BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0315.p (284 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0831 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Rso... 365 e-101 AGl3333 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Atu... 284 1e-76 SMc04145 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Sm... 267 2e-71 AGl1767 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Atu... 226 7e-59 DRA0222 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Dra... 181 1e-45 VNG0128C [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Hb... 113 6e-25 mll1234 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Mlo... 71 3e-12 MA4464 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Mac ... 69 2e-11 TVN0454 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Tvo... 67 4e-11 Ta1111 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Tac ... 65 2e-10 >RSp0831 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Rso Ralstonia solanacearum Length = 282 Score = 365 bits (936), Expect = e-101, Method: Compositional matrix adjust. Identities = 178/274 (64%), Positives = 207/274 (75%), Gaps = 4/274 (1%) Query: 6 DVAAWQTARFSRLLLTGAAGGVGKQLRARLASFAEVVRVADLASAMAAVDPAAAHEEVLG 65 D A R RLLLTGA G +GK LR RL +AEV+RV+D+ AA A EEV+ Sbjct: 11 DPLAGIATRCHRLLLTGAGGNLGKVLRERLTRYAEVLRVSDITDLCAA----RAGEEVVP 66 Query: 66 CDLADRAAVDAMVAGCEAIIHLGGVSVERPFEEILEANIKGVFHIYEAARRHGVKRVIFA 125 CDLAD AVDA+V G +AI+HLGG+SVERPF+EIL ANI+G +H+YEAARRHGVKR+ FA Sbjct: 67 CDLADAQAVDALVKGVDAIVHLGGISVERPFDEILPANIQGTYHLYEAARRHGVKRIAFA 126 Query: 126 SSNHVTGFYGQDERIDARDMKRPDGYYGLSKSYGEDMAQFYFDRYGVETVSIRIGSIFPE 185 SSNH GFY Q E IDAR RPDGYYGLSK +GE + FYFDRYG+ETV+IRIGS FPE Sbjct: 127 SSNHAIGFYRQGEVIDARVPTRPDGYYGLSKVFGEQLGSFYFDRYGIETVAIRIGSSFPE 186 Query: 186 ATNRRMLASWMSMDDFEQLLRRSLFIPDVGHTIVYGMSANAKTWWDNRYAAHLGYAPKDS 245 A +RRML +W+ DD EQL+RR+LF+P+VG TIVYGMS N + WWDNR+AAHLGY P S Sbjct: 187 AKDRRMLVTWLGYDDLEQLIRRALFVPNVGFTIVYGMSGNREAWWDNRHAAHLGYVPAQS 246 Query: 246 SEIFRAKVEAQPMPAPDDPVLTLQGGAFTTAGPF 279 SE FRA+VEAQP A DDP QGGAF AGPF Sbjct: 247 SEAFRAQVEAQPPLAADDPAARFQGGAFVKAGPF 280 >AGl3333 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 283 Score = 284 bits (727), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 133/261 (50%), Positives = 181/261 (69%), Gaps = 5/261 (1%) Query: 15 FSRLLLTGAAGGVGKQLRARLASFAEVVRVADLASAMAAVDPAAAHEEVLGCDLADRAAV 74 RLL+TGAAG +G+ +R RLA AE++R+ADL+ +DPA +EE + CDLAD AV Sbjct: 19 MKRLLVTGAAGQLGRVMRERLAPMAEILRLADLSP----LDPAGPNEECVQCDLADANAV 74 Query: 75 DAMVAGCEAIIHLGGVSVERPFEEILEANIKGVFHIYEAARRHGVKRVIFASSNHVTGFY 134 +AMVAGC+ I+HLGG+SVE+PFE+IL+ NI G++++YEAAR HG R++FASSNH G+Y Sbjct: 75 NAMVAGCDGIVHLGGISVEKPFEQILQGNIIGLYNLYEAARAHGQPRIVFASSNHTIGYY 134 Query: 135 GQDERIDARDMKRPDGYYGLSKSYGEDMAQFYFDRYGVETVSIRIGSIFPEATNRRMLAS 194 Q ER+ RPDG YG+SK +GE++A+ YFD++G ET +RIGS PE N RML++ Sbjct: 135 PQTERLGPDVPARPDGLYGVSKCFGENLARMYFDKFGQETALVRIGSCTPEPNNYRMLST 194 Query: 195 WMSMDDFEQLLRRSLFIPDVGHTIVYGMSANAKTWWDNRYAAHLGYAPKDSSEIFRAKV- 253 W S DDF L+ P +G +V+G SAN WWDN + LG+ PKD++E FR + Sbjct: 195 WFSHDDFVSLIEAVFRAPVLGCPVVWGASANDAGWWDNSHLGFLGWKPKDNAEAFRRHIT 254 Query: 254 EAQPMPAPDDPVLTLQGGAFT 274 E P P P+D ++ QGG F Sbjct: 255 ETTPPPDPNDALVRFQGGTFV 275 >SMc04145 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Sme Sinorhizobium meliloti Length = 261 Score = 267 bits (682), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 130/261 (49%), Positives = 184/261 (70%), Gaps = 6/261 (2%) Query: 16 SRLLLTGAAGGVGKQLRARLASFAEVVRVADLASAMAAVDPAAAHEEVLGCDLADRAAVD 75 +RLL+TGAAGG+G+ R L A+V+R++D+A+ + PA EE++ CDLA+R AVD Sbjct: 3 TRLLITGAAGGLGRYAREGLKGCADVLRLSDVAT----LSPAGEGEEIVRCDLAEREAVD 58 Query: 76 AMVAGCEAIIHLGGVSVERPFEEILEANIKGVFHIYEAARRHGVKRVIFASSNHVTGFYG 135 +V GC+AI+HLG +SVE F+ +L+ANI G +++YEAAR+ GV R++FAS+NHVTGF+ Sbjct: 59 QLVRGCDAILHLGAISVESDFDALLQANILGTYNLYEAARKAGVNRILFASTNHVTGFHP 118 Query: 136 QDERIDARDMKRPDGYYGLSKSYGEDMAQFYFDRYGVETVSIRIGSIFPEATNRRMLASW 195 E +D +RPD YG+SK +GED+++ YFD+YG+ET +RIGS F E TNRRML++W Sbjct: 119 IGETLDHLSPRRPDSLYGVSKCFGEDLSRLYFDKYGMETACLRIGSCFAEPTNRRMLSTW 178 Query: 196 MSMDDFEQLLRRSLFIPDVGHTIVYGMSANAKTWWDNRYAAHLGYAPKDSSEIFRAKVEA 255 +S DF L+RR L P +GH ++YG+SAN WW N +A LG+ P+DSSE +R ++E Sbjct: 179 LSPRDFLALVRRLLDAPKIGHLVLYGVSANRDVWWSNGHADFLGWRPQDSSEPYRHEIEK 238 Query: 256 QPMPAPDDPVLTLQGGAFTTA 276 + P D V QGG A Sbjct: 239 RE-EEPSDGV-RYQGGRHAAA 257 >AGl1767 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 265 Score = 226 bits (575), Expect = 7e-59, Method: Compositional matrix adjust. Identities = 109/260 (41%), Positives = 165/260 (63%), Gaps = 5/260 (1%) Query: 15 FSRLLLTGAAGGVGKQLRARLASFAEVVRVADLASAMAAVDPAAAHEEVLGCDLADRAAV 74 RLL+TGA G +G LR RL A+ +R++D+ + A+ HEE++ C L D AV Sbjct: 2 LKRLLITGAGGKLGSMLRGRLGHVAQTIRLSDVVD----LGSASPHEELVSCALEDEQAV 57 Query: 75 DAMVAGCEAIIHLGGVSVERPFEEILEANIKGVFHIYEAARRHGVKRVIFASSNHVTGFY 134 +V GC+ I+HLGGVSVER F+ I AN++GV+++YEAAR +G+ R++FASSNH G+Y Sbjct: 58 HDLVKGCDGIVHLGGVSVERAFDPIEAANLRGVYNLYEAARLNGMPRILFASSNHTIGYY 117 Query: 135 GQDERIDARDMKRPDGYYGLSKSYGEDMAQFYFDRYGVETVSIRIGSIFPEATNRRMLAS 194 Q +++ PDG YG+SK +GE MA Y ++G ET +RIGS + +N RML++ Sbjct: 118 PQGQQLAPDTPFLPDGLYGVSKIFGEAMASLYHSKFGQETAIVRIGSCEEKPSNWRMLST 177 Query: 195 WMSMDDFEQLLRRSLFIPDVGHTIVYGMSANAKTWWDNRYAAHLGYAPKDSSEIFRAKVE 254 W+S DF L+ + P +G +++G+SAN +WWDN + LG+ +D++ +RA++E Sbjct: 178 WLSHGDFVSLIEATFRAPKLGCPVIWGVSANDDSWWDNSHVDFLGWQRRDNAADYRAEIE 237 Query: 255 AQ-PMPAPDDPVLTLQGGAF 273 P P+ + QGG F Sbjct: 238 RDVSRPDPEAAIAKYQGGIF 257 >DRA0222 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Dra Deinococcus radiodurans Length = 288 Score = 181 bits (460), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 103/242 (42%), Positives = 141/242 (58%), Gaps = 8/242 (3%) Query: 17 RLLLTGAAGGVG----KQLRARLASFAEVVRVADLASAMAAVDPAAAHEEVLGCDLADRA 72 RLL+TGAAG VG + LR L ++R+ D + A P EEV+ DL D Sbjct: 5 RLLITGAAGEVGSALRELLRGPLGQHFPIIRLTD-NRDLGAARPG---EEVMLADLTDFN 60 Query: 73 AVDAMVAGCEAIIHLGGVSVERPFEEILEANIKGVFHIYEAARRHGVKRVIFASSNHVTG 132 AV ++ G +A+IHL G+ E + I NI G +H+ EAAR+ GV+RV FASS H G Sbjct: 61 AVLKVMQGVDAVIHLAGIPDEDSYANIRAVNIDGTYHVLEAARQAGVRRVAFASSIHTVG 120 Query: 133 FYGQDERIDARDMKRPDGYYGLSKSYGEDMAQFYFDRYGVETVSIRIGSIFPEATNRRML 192 FY + E I RPD YYG+SK +GE + + Y++RYG+E V +RI S P +RR L Sbjct: 121 FYPRTEIISPTVPVRPDTYYGVSKVFGEALGRMYWERYGLEFVGVRICSFQPRPKDRRHL 180 Query: 193 ASWMSMDDFEQLLRRSLFIPDVGHTIVYGMSANAKTWWDNRYAAHLGYAPKDSSEIFRAK 252 ++W+S D QL R++ PDVG +V G+S N + W LGY P+D +E F A+ Sbjct: 181 STWLSPRDATQLFARAVTAPDVGFLVVAGISGNTRRWMSPEGWDVLGYVPQDDAERFAAE 240 Query: 253 VE 254 VE Sbjct: 241 VE 242 >VNG0128C [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Hbs Halobacterium sp. NRC-1 Length = 259 Score = 113 bits (282), Expect = 6e-25, Method: Compositional matrix adjust. Identities = 83/245 (33%), Positives = 121/245 (49%), Gaps = 23/245 (9%) Query: 18 LLLTGAAGGVGKQLRARLASFAEVVRVADLASAMAAVDPAAAHEEVLGCDLADRAAVDAM 77 +LLTGA+G VG+ + + R+ D D HE V+ D+ D AV Sbjct: 9 VLLTGASGRVGQAILGGIGD-DYTWRLFDREPPTDDPD----HEFVV-ADITDETAVREA 62 Query: 78 VAGCEAIIHLGG-VSVERPFEEILEANIKGVFHIYEAARRHGVKRVIFASSNHVTGFYGQ 136 + AI+HL G E P+E +L NI G + +AA GV RV+FASSNH G Y Sbjct: 63 ASDVGAIVHLAGDPRPEAPWESVLRNNIDGTRTVLDAALAAGVDRVVFASSNHAVGHYET 122 Query: 137 DE-----------RIDARDMKRPDGYYGLSKSYGEDMAQFYFDRYGVETVSIRIGSI--- 182 D R+D + RP YG+SK+ GE + ++Y D +G+ ++RIG++ Sbjct: 123 DRKPDLYRSDDDFRLDGTERPRPGNLYGVSKAAGETLGRYYHDEHGLTFAAVRIGNLTAG 182 Query: 183 FPEATNRRMLASWMSMDDFEQLLRRSLFIPDVGHTIVYGMSANAKTWWD-NRYAAHLGYA 241 P R A W+S D L+ R L D + +VYG+S N + ++ R LGY Sbjct: 183 HPPIDYERGQAMWLSPRDCAHLIDRCLSA-DYDYEVVYGISDNDRKYYSLARAKDALGYE 241 Query: 242 PKDSS 246 P+D+S Sbjct: 242 PRDNS 246 >mll1234 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Mlo Mesorhizobium loti Length = 307 Score = 70.9 bits (172), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 70/276 (25%), Positives = 116/276 (42%), Gaps = 33/276 (11%) Query: 17 RLLLTGAAGGVGKQLRARLASFAEVVRVADLASAMAAVDPAAAHEEVLGCDLADRAAVDA 76 R+LLTG++G +G L RL + L + +DP + E + +ADR V Sbjct: 2 RILLTGSSGWLGSALAPRLRA---------LGHEVIGLDPVPSVETQMIGSIADRDLVMQ 52 Query: 77 MVAG--CEAIIHLGGV---SVE-RPFEEILEANIKGVFHIYEAARRHGVKRVIFASSNHV 130 ++ EAIIH G + ++E R + + N++G ++ +AA GV+R +F S+ + Sbjct: 53 VIGDNRIEAIIHSGALHKPNIESRANSDFVATNVQGTLNLLDAAVASGVQRFVFTSTTSL 112 Query: 131 T-------GFYGQDER---IDARDMKRPDGYYGLSKSYGEDMAQFYFDRYGVETVSIRIG 180 GF G + + P YG++K E + + Y R+G+ V +R Sbjct: 113 MISQAIRDGFKGGARKAAWLTEAMSPEPRNIYGVTKLSAEHLCRLYHLRHGLPVVVLRTA 172 Query: 181 SIFPEATNRRMLASWMSMDD----FEQLLRRSLFIPDVGHTIVYGMSANAKTWWDN-RYA 235 FPEA + +A + D +LL R L + D V + + +D Sbjct: 173 RFFPEADD---MAHTIEQSDANTKANELLFRRLTVEDAAEAHVAALEKAPQLGFDTFIIC 229 Query: 236 AHLGYAPKDSSEIFRAKVEAQPMPAPDDPVLTLQGG 271 A + P D + R PD P L + G Sbjct: 230 APTPFRPDDCDALIRDAPAVVARHFPDFPTLYARKG 265 >MA4464 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Mac Methanosarcina acetivorans str.C2A Length = 298 Score = 68.6 bits (166), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 46/175 (26%), Positives = 87/175 (49%), Gaps = 12/175 (6%) Query: 17 RLLLTGAAGGVGKQLRARLASFAEVVRVAD-LASAMAAVDPAAAHEEVLGCDLADRAAVD 75 ++L+TG AG +G + A VR+ D L + + P + E + D+ D ++V+ Sbjct: 2 KVLITGGAGFIGSHIAEYFAEAGHSVRILDNLTTGFSRNIPQHRNVEFIQGDICDPSSVE 61 Query: 76 AMVAGCEAIIHLGG-----VSVERPFEEILEANIKGVFHIYEAARRHGVKRVIFASSNHV 130 V+G + + H +S E+P E N G ++ +A R GV++ + ASS V Sbjct: 62 KAVSGMDCVFHEAALVSVPLSCEKPVEA-FRINTLGTLNVLQACVRAGVEKFVTASSAAV 120 Query: 131 TGFYGQDERIDARDMKRPD--GYYGLSKSYGEDMAQFYFDRYGVETVSIRIGSIF 183 YG + + R+ P+ Y +SK GE +A+ +++ +G+ T +R +++ Sbjct: 121 ---YGNNPELPKRENMYPEPASPYAISKLDGEYLARMFYEEHGLRTTCLRYFNVY 172 >TVN0454 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Tvo Thermoplasma volcanium Length = 317 Score = 67.0 bits (162), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 46/171 (26%), Positives = 88/171 (51%), Gaps = 9/171 (5%) Query: 18 LLLTGAAGGVGKQLRARLASFAEVVRVADLASAMAAVDPAAAHEEVLGCDLADRAAVDAM 77 +L+TG++G +G +L LA V +AS + D + + D+++R +D Sbjct: 2 ILVTGSSGQIGTELVPYLAEKYGKKNV--IASDIVQRDTGGI--KFITLDVSNRDEIDRA 57 Query: 78 VA--GCEAIIHLGGV---SVERPFEEILEANIKGVFHIYEAARRHGVKRVIFASSNHVTG 132 V +AI HL G+ E+ + N+ G ++I EAA++H V++V+ S+ V G Sbjct: 58 VEKYSIDAIFHLAGILSAKGEKDPALAYKVNMNGTYNILEAAKQHRVEKVVIPSTIGVFG 117 Query: 133 FYGQDERIDARDMKRPDGYYGLSKSYGEDMAQFYFDRYGVETVSIRIGSIF 183 ++ + + RP YG++K E + Q+Y++++G++ S+R I Sbjct: 118 PETPKNKVPSITITRPRTMYGVTKIAAELLGQYYYEKFGLDVRSLRYPGII 168 >Ta1111 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Tac Thermoplasma acidophilum Length = 317 Score = 65.1 bits (157), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 42/171 (24%), Positives = 81/171 (47%), Gaps = 9/171 (5%) Query: 18 LLLTGAAGGVGKQLRARLASFAEVVRVADLASAMAAVDPAAAHEEVLGCDLADRAAVDAM 77 +L+TG++G +G +L + D + ++P + D+ DR ++D Sbjct: 2 ILVTGSSGQIGTEL----VPYLREKYGKDSVISSDIMEPTGTQTGYIRLDVTDRDSLDRA 57 Query: 78 VA--GCEAIIHLGGV---SVERPFEEILEANIKGVFHIYEAARRHGVKRVIFASSNHVTG 132 + G I HL G+ E+ + N+ G +++ EAARRH + +VI S+ V G Sbjct: 58 IEKYGITDIFHLAGILSAKGEKDPDLAYRVNLNGTYNVLEAARRHSLDKVIIPSTIGVFG 117 Query: 133 FYGQDERIDARDMKRPDGYYGLSKSYGEDMAQFYFDRYGVETVSIRIGSIF 183 + + + RP YG++K E + Q+Y++++ ++ S+R I Sbjct: 118 PETPKRNVPSITVLRPRTMYGVTKVAAELLGQYYYEKFRLDVRSLRYPGII 168