BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0296.p (433 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mlr9217 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tet... 345 2e-94 BS_yxeK [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tet... 331 2e-90 AGpT161 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tet... 326 6e-89 SMb21691 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene te... 313 5e-85 AGl2922 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tet... 304 3e-82 AGl2773 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tet... 303 6e-82 mll5137 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tet... 299 1e-80 mll2278 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tet... 295 1e-79 mll9178 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tet... 295 2e-79 mlr7299 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tet... 281 2e-75 >mlr9217 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Mlo Mesorhizobium loti Length = 426 Score = 345 bits (884), Expect = 2e-94, Method: Compositional matrix adjust. Identities = 183/434 (42%), Positives = 255/434 (58%), Gaps = 11/434 (2%) Query: 1 MHLAAFLIAGNAAHSQALWRHPQSRRGGFLELDYYLHIARTLERGKFDLLFFADRLAVST 60 M AFL+AG H A+WRHPQ+ FL+ ++ + RTLE G+FD LFFAD L+ Sbjct: 1 MKFVAFLLAGPTCHHHAMWRHPQTENR-FLDPAFWETLGRTLEAGRFDGLFFADVLSF-- 57 Query: 61 RYGDSHLHGLYVGDQDATRLDPLPILGALAAATSHIGLGATRSTTYSQPYSLAREFATLD 120 H + LDP+P++ +A ATS IGLG T STT+ PY++AR ++LD Sbjct: 58 -----HNETTMTRGGQMSLLDPVPLVAMMARATSRIGLGVTLSTTFQDPYAIARVLSSLD 112 Query: 121 HLSGGRAAWNVVTSVNQGEADNFGLKETLPHDVRYDRADEFLEVTHKLWHSWQPDALRLQ 180 LSGGR AWN+VTS + +A FG + LP RY+RA+E L+V LW W AL L Sbjct: 113 VLSGGRIAWNIVTSFSDLDAQIFGEEALLPRSERYERAEEVLKVCLDLWTGWADGALVLD 172 Query: 181 QDR--YADADKVAAIDHQGAHFSVRGPLNIPASPQGHPVIIQAGSSDRGQDFAARWAEVV 238 ++ + D KV + G + RG +P SPQ HPVI+QAGSS RG+DFAA AE+V Sbjct: 173 KESGDFIDEAKVRRTEIAGKYVGARGVFTVPPSPQRHPVIMQAGSSPRGRDFAASHAELV 232 Query: 239 FNIQPDLPRLQAFYRDLKNRAQQFGRRPQDIRILSAVMPFVGQSRQHARELQEQANALAD 298 F +Q LP +Q FY ++K+R + GR P D IL +V P VG++ ARE Q N L D Sbjct: 233 FTLQHSLPDMQEFYAEMKDRVGRAGRNPDDCAILVSVDPIVGETNSLAREKQAYINDLVD 292 Query: 299 PLVGLSTLSSHMNVDFSGFALDAPLGDVQV-SGIQGLFKLLRAISAERQLTLADAGRLYA 357 P VG+ +S H +D S + +D P+ D+ +G +G F ++ + LTL +A + +A Sbjct: 293 PHVGIPFMSDHTGLDLSQYPVDKPIIDIPAETGSRGSFDIILQGTKANNLTLGEAAKHFA 352 Query: 358 QGVLTPQIAGTAADVADWLQSIIVANGADGFVISPSHLPYGFDDFVDQVIPELQRRGAFR 417 L PQ+ GT VAD LQ G DGF+++P+ +P F+ F V+P LQ+RG FR Sbjct: 353 VSELCPQVVGTPETVADQLQDFFENKGCDGFIVTPTEMPGSFEAFTRSVVPILQKRGLFR 412 Query: 418 QDYAGRQLRQHLAA 431 ++Y G LR+ + A Sbjct: 413 KEYPGSTLRETIKA 426 >BS_yxeK [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Bsu Bacillus subtilis Length = 441 Score = 331 bits (849), Expect = 2e-90, Method: Compositional matrix adjust. Identities = 176/435 (40%), Positives = 255/435 (58%), Gaps = 18/435 (4%) Query: 1 MHLAAFLIAGNAAHSQALWRHPQSRRGGFLELDYYLHIARTLERGKFDLLFFADRLAVST 60 + L FL H A WRHP + + LDY+ +A+T ERGK D+LF AD L++ + Sbjct: 8 IKLGVFL--AGTGHHVASWRHPDAPSDASMNLDYFKELAKTAERGKLDMLFLADSLSIDS 65 Query: 61 RYGDSHLHGLYVGDQDATRLDPLPILGALAAATSHIGLGATRSTTYSQPYSLAREFATLD 120 + SH + L TR +P +L ALA TS IGL AT STTYS+P+ +AR+FA+LD Sbjct: 66 K---SHPNVL-------TRFEPFTLLSALAQVTSKIGLTATASTTYSEPFHIARQFASLD 115 Query: 121 HLSGGRAAWNVVTSVNQGEADNFGLKETLPHDVRYDRADEFLEVTHKLWHSWQPDALRLQ 180 HLS GRA WNVVTS + A NF ++ L H +RY RA+EF+E+ LW SW+ DA Sbjct: 116 HLSNGRAGWNVVTSSIESTALNFSGEKHLEHHLRYQRAEEFVEIVKGLWDSWEEDAFIRN 175 Query: 181 QD--RYADADKVAAIDHQGAHFSVRGPLNIPASPQGHPVIIQAGSSDRGQDFAARWAEVV 238 ++ + D +K+ ++H+G +FSVRGPLN+ +PQG PVIIQAGSS G+ AA+ AEV+ Sbjct: 176 KETGEFFDKEKMHELNHKGEYFSVRGPLNVSRTPQGQPVIIQAGSSGDGKALAAKTAEVI 235 Query: 239 FNIQPDLPRLQAFYRDLKNRAQQFGRRPQDIRILSAVMPFVGQSRQHARELQEQANALAD 298 F Q L Q FY+ +K +A +FGR P+ I I+ + P + + + A+ ++ L Sbjct: 236 FTAQNHLESAQEFYQSIKEQAAEFGRDPEKIAIMPGIFPIIADTEEAAQAKYKELQDLII 295 Query: 299 PLVGLSTLSSHM-NVDFSGFALDAPLGDVQV---SGIQGLFKLLRAISAERQLTLADAGR 354 P VGL L +++ +D S + LD PL + + ++ FKL++ ++ +T+ + + Sbjct: 296 PSVGLQILQNYLGGIDLSAYPLDGPLPKLDAEASNAVKSRFKLVQEMAERDNMTIRELYK 355 Query: 355 LYAQGVLTPQIAGTAADVADWLQSIIVANGADGFVISPSHLPYGFDDFVDQVIPELQRRG 414 A GT +AD +Q + DGF I P LP G + FVDQV+P LQ RG Sbjct: 356 YVAGSRGHHIFVGTPEQLADKMQEWVDTKACDGFNIMPPLLPEGIEVFVDQVVPILQERG 415 Query: 415 AFRQDYAGRQLRQHL 429 FR++Y G LR+H Sbjct: 416 VFRKEYEGTTLREHF 430 >AGpT161 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 450 Score = 326 bits (836), Expect = 6e-89, Method: Compositional matrix adjust. Identities = 177/433 (40%), Positives = 258/433 (59%), Gaps = 9/433 (2%) Query: 1 MHLAAFLIAGNAAHSQALWRHPQSRRGGFLELDYYLHIARTLERGKFDLLFFADRLAVST 60 MHLA +L AG WR P+S G ++ Y +AR E K D+LF AD+L++ Sbjct: 1 MHLALYLEAGTHLGG---WRLPESATSGGVDWALYKTVARRAEAAKLDMLFVADKLSIDD 57 Query: 61 RYGDSHLHGLYVGDQDATRLDPLPILGALAAATSHIGLGATRSTTYSQPYSLAREFATLD 120 YG V + TR +PL L AL A T HIG+G T S++Y+ PY+ AR A +D Sbjct: 58 NYGQHFADT--VKYRLVTRPEPLTTLAALGAVTDHIGIGGTISSSYASPYAAARMLANID 115 Query: 121 HLSGGRAAWNVVTSVNQGEADNFGLKETLPHDVRYDRADEFLEVTHKLWHSWQPDALRLQ 180 H+SGGRAAWN+VTSV+ GEA NFG ++ H+ RY RA EF +V KLW SW+ DAL L Sbjct: 116 HISGGRAAWNLVTSVSDGEARNFGREQHFGHEERYLRAIEFADVMGKLWDSWEADALVLD 175 Query: 181 QDR--YADADKVAAIDHQGAHFSVRGPLNIPASPQGHPVIIQAGSSDRGQDFAARWAEVV 238 + +AD+ K IDH+G F +RGP+N+P PQG PV+IQAG SDR Q AA+ AEV+ Sbjct: 176 KKSGVFADSTKFHYIDHEGDFFKIRGPINVPRPPQGRPVLIQAGVSDRFQGIAAQNAEVI 235 Query: 239 FNIQPDLPRLQAFYRDLKNRAQQFGRRPQDIRILSAVMPFVGQSRQHARELQEQANALAD 298 F + +L R ++FY+ K + + GR +++L ++P VG++R+ A + + + L Sbjct: 236 FVVHAELERARSFYKSFKEKVVEGGRSENAVKVLPGIVPVVGRTRKEALDKERELKELIL 295 Query: 299 PLVGLSTLSSHMNVDFSGFALDAPLGDV--QVSGIQGLFKLLRAISAERQLTLADAGRLY 356 P GLS +S+ MN D + F +AP D+ +++G G F+ + + E+++T+A+ G+ Y Sbjct: 296 PEAGLSFMSASMNFDLAQFPQNAPFPDITDKITGSVGRFQYVIKRAIEQKMTVAEVGKWY 355 Query: 357 AQGVLTPQIAGTAADVADWLQSIIVANGADGFVISPSHLPYGFDDFVDQVIPELQRRGAF 416 A+ + GT +VA L DGFVI P ++ D F++ V+P LQ RG F Sbjct: 356 AESLSFFAPVGTPEEVASQLAHWYAQRACDGFVILPPYIRRDEDLFLEGVVPVLQERGLF 415 Query: 417 RQDYAGRQLRQHL 429 R++Y G LR+ L Sbjct: 416 RREYPGTTLRETL 428 >SMb21691 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Sme Sinorhizobium meliloti Length = 449 Score = 313 bits (802), Expect = 5e-85, Method: Compositional matrix adjust. Identities = 185/435 (42%), Positives = 248/435 (57%), Gaps = 16/435 (3%) Query: 1 MHLAAFLIAGNAAHSQALWRHPQSRRGGFLELDYYLHIARTLERGKFDLLFFADRLAVST 60 + L AFL G A WRHP + G +++ +A T ERG FD F AD L+V Sbjct: 5 IKLGAFLPGG--GQHIAAWRHPDAPADGATNFEFHRRLAETAERGLFDAYFLADNLSVG- 61 Query: 61 RYGDSHLHGLYVGDQDATRLDPLPILGALAAATSHIGLGATRSTTYSQPYSLAREFATLD 120 L G G+ +P+ + ALA T+H+G AT STTY +PY+LAR+FA+LD Sbjct: 62 ------LGGREGGNAKIAGFEPVTLFAALAPLTTHLGFIATASTTYEEPYTLARKFASLD 115 Query: 121 HLSGGRAAWNVVTSVNQGEADNFGLKETLP-HDVRYDRADEFLEVTHKLWHSWQPDALRL 179 LS GRA WNVVTS A NF +ET P H RY+RA E +E LW SW+ DA Sbjct: 116 LLSNGRAGWNVVTSAGDETARNFN-RETQPSHADRYERAHEHVETVKALWDSWEDDAFIR 174 Query: 180 QQ--DRYADADKVAAIDHQGAHFSVRGPLNIPASPQGHPVIIQAGSSDRGQDFAARWAEV 237 + R+ DA +V IDH+G HFSV+GPLN P QGHPV++QAG S+ G+ AA AEV Sbjct: 175 DKATGRFFDAGRVHDIDHKGKHFSVKGPLNAPRPVQGHPVVVQAGQSEDGRRLAAVSAEV 234 Query: 238 VFNIQPDLPRLQAFYRDLKNRAQQFGRRPQDIRILSAVMPFVGQSRQHARELQEQANALA 297 +F +L Q FYRD+K R ++ GR P+ + I+ V PFVG++ + AR E+ NAL Sbjct: 235 IFTAHQNLASAQEFYRDIKARVKRAGRNPEHVLIMPGVAPFVGRTEEEARSKYEELNALI 294 Query: 298 DPLVGLSTLS--SHMNVDFSGFALDAPLG-DVQVSGIQGLFKLLRAISAERQLTLADAGR 354 P G++ L+ + +D +G+ LD PL + G++ L+R I+ E T+ + Sbjct: 295 VPEDGVALLNGLTGGTLDLTGYPLDGPLPVSNETEGMKSRQALIRKIADEHGFTIRQLYQ 354 Query: 355 LYAQGVLTPQIAGTAADVADWLQSIIVANGADGFVISPSHLPYGFDDFVDQVIPELQRRG 414 A + G+A VAD L+ ++ ADGF I P LP DDFVD VIP LQRRG Sbjct: 355 WIATARGHYTVVGSAEQVADQLEEWFLSEAADGFNILPPWLPGALDDFVDLVIPILQRRG 414 Query: 415 AFRQDYAGRQLRQHL 429 FR Y GR LR++L Sbjct: 415 LFRTAYEGRTLRENL 429 >AGl2922 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 436 Score = 304 bits (778), Expect = 3e-82, Method: Compositional matrix adjust. Identities = 177/432 (40%), Positives = 237/432 (54%), Gaps = 17/432 (3%) Query: 1 MHLAAFLIAGNAAHSQALWRHPQSRRGGFLELDYYLHIARTLERGKFDLLFFADRLAVST 60 MHL FL A H + WRHP + G D + + E KFD++F AD L Sbjct: 10 MHLGLFL--QGAGHHVSGWRHPDAEAGS-ENFDLLTRVTKMAEAAKFDMVFLADGLTSGV 66 Query: 61 RYGDSHLHGLYVGDQDATRLDPLPILGALAAATSHIGLGATRSTTYSQPYSLAREFATLD 120 D+H + R +PL +L ALA T IGL AT STTY +PY AR FA++D Sbjct: 67 ---DAHPSMI-------ARFEPLTLLAALAMVTDKIGLAATASTTYGEPYHTARAFASID 116 Query: 121 HLSGGRAAWNVVTSVNQGEADNFGLKETLPHDVRYDRADEFLEVTHKLWHSWQPDAL--R 178 HLS GRAAWN+VT+ A NF K HD RY A+E++ V LW SW DA Sbjct: 117 HLSHGRAAWNIVTTSYARTAANFS-KSHPEHDERYAVAEEYVNVVRGLWDSWDDDAFVKD 175 Query: 179 LQQDRYADADKVAAIDHQGAHFSVRGPLNIPASPQGHPVIIQAGSSDRGQDFAARWAEVV 238 Q RY D +KV +DH+G +F+V+GPLNIP SPQGHPV+IQAGSS GQD AAR A++V Sbjct: 176 KQAGRYVDPEKVHILDHEGKYFTVKGPLNIPRSPQGHPVLIQAGSSGPGQDLAARTADIV 235 Query: 239 FNIQPDLPRLQAFYRDLKNRAQQFGRRPQDIRILSAVMPFVGQSRQHARELQEQANALAD 298 F Q + QAFY LK R +FGR P + ++ MP +G+S + A E ++ N D Sbjct: 236 FTAQQAISEAQAFYTSLKARVAKFGRDPASVAVMPGFMPIIGRSFEEAGEKLKELNRWTD 295 Query: 299 PLVGLSTLSSHMNVDFSGFALDAPLGDVQVSG-IQGLFKLLRAISAERQLTLADAGRLYA 357 + L + + + LD PL D+ +S ++ +LL ++ +LT+ + A Sbjct: 296 IKNAMPLLEERIGHSLADYDLDGPLPDLPISDQLRSRAELLTELARREKLTIRELALRVA 355 Query: 358 QGVLTPQIAGTAADVADWLQSIIVANGADGFVISPSHLPYGFDDFVDQVIPELQRRGAFR 417 G + GTA +VAD +Q ADGF + P P G ++F +V+P LQ RG FR Sbjct: 356 AGRGHHIVMGTAKEVADRMQQWFENGAADGFNVMPPFFPGGLEEFNREVVPLLQERGLFR 415 Query: 418 QDYAGRQLRQHL 429 +DY G LR HL Sbjct: 416 KDYEGSTLRDHL 427 >AGl2773 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 450 Score = 303 bits (775), Expect = 6e-82, Method: Compositional matrix adjust. Identities = 178/440 (40%), Positives = 237/440 (53%), Gaps = 33/440 (7%) Query: 3 LAAFLIAGNAAHSQALWRHPQSRRGGFLELDYYLHIARTLERGKFDLLFFADR--LAVST 60 L AF+ G H +A WRHP+S ++ Y IAR E K D +FFAD L + Sbjct: 10 LNAFIYPG--GHHEAAWRHPESEPLRVTDIKLYQDIARKAEAAKLDAIFFADAPVLDANI 67 Query: 61 RYGDSHLHGLYVGDQDATRLDPLPILGALAAATSHIGLGATRSTTYSQPYSLAREFATLD 120 RY H RL+P+ +L ALAA T IG AT STTY +PY+LAR A++D Sbjct: 68 RYAARH------------RLEPITMLAALAAVTEKIGFIATASTTYYEPYNLARLLASVD 115 Query: 121 HLSGGRAAWNVVTSVNQGEADNFGLKETLPHDVRYDRADEFLEVTHKLWHSWQPDALRLQ 180 H+SGGR WN+VT+ A NF L++ PH RY +A EF+EV KLW SW+ DA+ Sbjct: 116 HISGGRVGWNIVTTSADAAAGNFNLQQHPPHADRYRQATEFVEVVTKLWDSWEDDAIVAD 175 Query: 181 QDR--YADADKVAAIDHQGAHFSVRGPLNIPASPQGHPVIIQAGSSDRGQDFAARWAEVV 238 ++ +AD D++ H G + VRG LN+P SPQG PV +QAGSS+ G+ FAAR+AE + Sbjct: 176 RESGLFADTDRIHPASHDGEFYRVRGALNLPRSPQGRPVYVQAGSSEDGRGFAARYAEAI 235 Query: 239 FNIQPDLPRLQAFYRDLKNRAQQFGRRPQDIRILSAVMPFVGQSRQHARELQEQANALAD 298 F L ++FY D+K R GR P ++IL + PF+ + + AR+L+ N L Sbjct: 236 FTAHQTLESARSFYSDIKRRVAATGRNPAHVKILPGISPFIASTEEEARKLEASFNDLIQ 295 Query: 299 PLVGLSTLSSHMNVDFSGFALDAPLGDVQVSGIQGLFKLLRAISAERQLTLADAGR---- 354 P L L +D S LD PL V + +A S+ QL L R Sbjct: 296 PAFSLGQLQRITGIDLSSADLDQPLPKEAVEATRA-----QADSSRHQLVLDVIDRENPT 350 Query: 355 ------LYAQGVLTPQIAGTAADVADWLQSIIVANGADGFVISPSHLPYGFDDFVDQVIP 408 A G I+GT VADW+++ ADGF I P L GFD FVD+V+P Sbjct: 351 IRQLLHRLAGGRGHKVISGTPEQVADWIETWFREGAADGFNIMPPWLNGGFDIFVDEVVP 410 Query: 409 ELQRRGAFRQDYAGRQLRQH 428 L++RG FR+DY G LR H Sbjct: 411 ILKQRGLFREDYEGDTLRDH 430 >mll5137 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Mlo Mesorhizobium loti Length = 415 Score = 299 bits (765), Expect = 1e-80, Method: Compositional matrix adjust. Identities = 179/431 (41%), Positives = 240/431 (55%), Gaps = 28/431 (6%) Query: 1 MHLAAFLIAGNAAHSQALWRHPQSRRGGFLELDYYLHIARTLERGKFDLLFFADRLAVST 60 M L AFL A H A WRHP++ +++D+Y+ +ART E KFD++F D A Sbjct: 5 MKLGAFLWA--TGHHIAAWRHPKAHVTAGIDIDHYIQLARTAEAAKFDMIFCED--AAGL 60 Query: 61 RYGDSHLHGLYVGDQDATRLDPLPILGALAAATSHIGLGATRSTTYSQPYSLAREFATLD 120 R + G+ + +P+ +L ALA TS IGL +T ST+Y++PY LAR F +LD Sbjct: 61 REANV---GIASQTSRSIGFEPISLLSALAVQTSRIGLVSTASTSYNEPYGLARTFLSLD 117 Query: 121 HLSGGRAAWNVVTSVNQGEADNFGLKETLPHDVRYDRADEFLEVTHKLWHSWQPDALRLQ 180 HLSGGRA WN+VTS + EA NFG PH RY+RA EF V LW Sbjct: 118 HLSGGRAGWNLVTSASPIEAANFGSTGLKPHADRYERAREFAGVVTGLWRG--------- 168 Query: 181 QDRYADADKVAAIDHQGAHFSVRGPLNIPASPQGHPVIIQAGSSDRGQDFAARWAEVVFN 240 A H G FSVR PL++P SPQG PV++QAG+SD G+D AAR A+VVF Sbjct: 169 ----------KASGHDGQSFSVRDPLDLPRSPQGAPVMVQAGASDVGRDLAARTADVVFT 218 Query: 241 IQPDLPRLQAFYRDLKNRAQQFGRRPQDIRILSAVMPFVGQSRQHARELQEQANALADPL 300 +AFY DLK R +GR P DI+I+ V P V ++ ARE E+ L Sbjct: 219 AAQTFEEAKAFYDDLKGRMAAYGREPDDIKIMPGVSPVVAETEAEAREKHEELQVLIPDD 278 Query: 301 VGLSTLSSHMNV-DFSGFALDAPLGDV-QVSGIQGLFKLLRAISAERQLTLADAGRLYAQ 358 VG++ LSS++++ D + +D PL ++ + G++ L+ S L++ R +A Sbjct: 279 VGVALLSSYLSISDLWRYPIDGPLPELPESEGMKSRQALVVEQSRRDGLSIRQLARHFAG 338 Query: 359 GVLTPQIAGTAADVADWLQSIIVANGADGFVISPSHLPYGFDDFVDQVIPELQRRGAFRQ 418 +I GTAA VAD LQ+ ADGF + PS+ P D F V+PELQRRG FR+ Sbjct: 339 ARGHWRIVGTAAQVADELQARFEGGAADGFNVMPSYFPGELDAFATLVVPELQRRGLFRR 398 Query: 419 DYAGRQLRQHL 429 DY GR LR HL Sbjct: 399 DYEGRTLRDHL 409 >mll2278 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Mlo Mesorhizobium loti Length = 450 Score = 295 bits (755), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 175/436 (40%), Positives = 244/436 (55%), Gaps = 16/436 (3%) Query: 1 MHLAAFLIAGNAAHSQALWRHPQSRRGGFLELDYYLHIARTLERGKFDLLFFADRLAV-- 58 M L+AF H A WRHP++ L+ DYY + + ER + D +F AD +++ Sbjct: 4 MILSAFFFNPQGDHRMA-WRHPRAPGREVLDFDYYRELVQAAERARIDTIFVADHVSIWD 62 Query: 59 STRYGDSHLHGLYVGDQDATRLDPLPILGALAAATSHIGLGATRSTTYSQPYSLAREFAT 118 S + G +H RL+PL +L ALAA T HIGL T S++YS+PY++AR FA+ Sbjct: 63 SVKSGVAHYAN--------ARLEPLTLLSALAAVTKHIGLITTASSSYSEPYNVARLFAS 114 Query: 119 LDHLSGGRAAWNVVTSVNQGEADNFGLKETLPHDVRYDRADEFLEVTHKLWHSWQPDALR 178 LDH+S GRA+WNVVTS EA NFG + H RY+RA EFL++ LW SW+ +AL Sbjct: 115 LDHISKGRASWNVVTSAMDEEARNFGRDGNIEHAFRYERAGEFLDIVKALWDSWEDEALL 174 Query: 179 LQQDR--YADADKVAAIDHQGAHFSVRGPLNIPASPQGHPVIIQAGSSDRGQDFAARWAE 236 + ++ +AD DKV IDH+G HF VRGPLN+ PQGHP+I+QAGSS+ G++FA A+ Sbjct: 175 IDKETGYFADPDKVHPIDHKGKHFKVRGPLNVSRPPQGHPLIVQAGSSEDGKNFATAHAD 234 Query: 237 VVFNIQPDLPRLQAFYRDLKNRAQQFGRRPQDIRILSAVMPFVGQSRQHARELQEQANAL 296 F I + +D+ R + GRRP+ +IL ++P V S R+ QE L Sbjct: 235 AHFAIYSTREDGIKYRQDINERLARHGRRPESFKILPGILPIVAASEAEGRDKQEYLQTL 294 Query: 297 ADPLVGLSTLSSHMNVDFSGFALDAPLGDVQV-SGIQGLFKLLRAIS--AERQLTLADAG 353 VG+ LSS +D S + D PL + S G L + +++ L+L D Sbjct: 295 LPDQVGIDLLSSWSGIDLSAYPPDGPLPPLPDESTFNGGRTSLNRVKQWSKQNLSLRDIA 354 Query: 354 RLYAQGVLTPQIAGTAADVADWLQSIIVANGADGFVISPSHLPYGFDDFVDQVIPELQRR 413 R A P +AGT +AD L+ V+ ADGF + LP + +F +QV+PELQRR Sbjct: 355 RKLANSGSVPTVAGTPKQIADQLEDWFVSGAADGFNLMFPLLPEDWVNFAEQVVPELQRR 414 Query: 414 GAFRQDYAGRQLRQHL 429 G +YA LR L Sbjct: 415 GLVPTEYAPGTLRDRL 430 >mll9178 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Mlo Mesorhizobium loti Length = 448 Score = 295 bits (754), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 183/447 (40%), Positives = 245/447 (54%), Gaps = 41/447 (9%) Query: 1 MHLAAFLIAGNAAHSQALWRHPQSRRGGFLELDYYLHIARTLERGKFDLLFFAD--RLAV 58 ++L F+ G H +A WR+ +S L++ YY +A+ E KFD LFFAD LA Sbjct: 8 LNLNLFIYPG--GHHEAGWRYKESAPERVLDIAYYQELAKKAEASKFDALFFADGPALAD 65 Query: 59 STRYGDSHLHGLYVGDQDATRLDPLPILGALAAATSHIGLGATRSTTYSQPYSLAREFAT 118 + RY RL+PL + ALAA T IG AT STTY++PY+LAR FA+ Sbjct: 66 NIRYASRF------------RLEPLTWISALAAVTQRIGFIATASTTYNEPYNLARLFAS 113 Query: 119 LDHLSGGRAAWNVVTSVNQGEADNFGLKETLPHDVRYDRADEFLEVTHKLWHSWQPDALR 178 +DHLSGGRA WN+VT+ + A NFG H RY+RA EF++V KLW S + DAL Sbjct: 114 VDHLSGGRAGWNIVTTGDASAALNFGFDRHPTHADRYERAGEFVDVVTKLWDSCEDDAL- 172 Query: 179 LQQDR----YADADKVAAIDHQGAHFSVRGPLNIPASPQGHPVIIQAGSSDRGQDFAARW 234 DR +AD DK+ I+H G + V+GPL +P SPQG PV +QAGSS+ G+ FA+R+ Sbjct: 173 -VSDRASGIFADTDKIHPINHIGKYHRVKGPLTLPRSPQGRPVYVQAGSSEDGRSFASRY 231 Query: 235 AEVVFNIQPDLPRLQAFYRDLKNRAQQFGRRPQDIRILSAVMPFVGQSRQHARELQEQAN 294 AE +F L Q FY D+K R + GR P +++L + PF+G + AR L ++ N Sbjct: 232 AEAIFTAHQTLGNAQEFYADIKARVKSVGRNPDHVKVLPGISPFIGSTEAEARALHDEFN 291 Query: 295 ALADPLVGLSTLSSHMNVDFSGFALDAPLGD--VQVSGIQG----LFKLLRAISAE---- 344 L P L L ++ D SG+ LD P + V G +G +L I E Sbjct: 292 ELTQPEYSLDQLRRIVDADLSGYNLDGPFPRELISVEGERGASSRFHVVLDIIERENPTI 351 Query: 345 RQL--TLADAGRLYAQGVLTPQIAGTAADVADWLQSIIVANGADGFVISPSHLPYGFDDF 402 RQL LA A + Q AGT +AD +Q ADGF + P +L GFD F Sbjct: 352 RQLLHRLAGARGHWVQ-------AGTPDQIADKIQEWFDNGAADGFNVMPPYLQGGFDVF 404 Query: 403 VDQVIPELQRRGAFRQDYAGRQLRQHL 429 ++V+P L+RRG FR DY G LR H Sbjct: 405 PEEVVPILRRRGLFRHDYDGATLRDHF 431 >mlr7299 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Mlo Mesorhizobium loti Length = 451 Score = 281 bits (719), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 175/419 (41%), Positives = 233/419 (55%), Gaps = 19/419 (4%) Query: 19 WRHPQSRRGGFLELDYYLHIARTLERGKFDLLFFADRLAVSTRYGDSHLHGLYVGDQDAT 78 WR+P + + A+TLE KFD F AD LAV ++ V T Sbjct: 23 WRYPGAYPDANFNFAHLKRFAQTLEAAKFDAFFMADHLAVLNMPIEALRRSHTV-----T 77 Query: 79 RLDPLPILGALAAATSHIGLGATRSTTYSQPYSLAREFATLDHLSGGRAAWNVVTSVNQG 138 +P +L ALAA T HIGL AT STT+ PY +AR FA+LDH+SGGRA WN+VT+ N Sbjct: 78 SFEPFTLLSALAAVTDHIGLVATASTTFDAPYHIARRFASLDHISGGRAGWNIVTTSNPD 137 Query: 139 EADNFGLKETLPHDVRYDRADEFLEVTHKLWHSWQPDAL--RLQQDRYADADKVAAIDHQ 196 A NFGL E + HD RY RA EF +V LW S+ DA + Y D K+ +DH+ Sbjct: 138 AALNFGLDEHVEHDERYHRAREFYDVVTGLWDSFADDAFIRDAESGLYFDPAKLHVLDHK 197 Query: 197 GAHFSVRGPLNIPASPQGHPVIIQAGSSDRGQDFAARWAEVVFNIQPDLPRLQAFYRDLK 256 G H SVRGPLNI QG PVI+QAG+S+ G+ AA AEV+F DL Q F+ D+K Sbjct: 198 GEHLSVRGPLNIARPVQGWPVIVQAGASEAGRQLAAETAEVIFAAHADLAAGQHFFADVK 257 Query: 257 NRAQQFGRRPQDIRILSAVMPFVGQSRQHARELQEQANALADPLVGLSTLSSHMNVDFSG 316 RAQ+ GR DI+IL VG S + AR + + ++L G+++LS + + S Sbjct: 258 GRAQKLGRSRDDIKILPGAFVVVGDSVEDARAKRAKLDSLVYYESGIASLSIALGHNASA 317 Query: 317 FALDAPLGDV-----QVSGIQGLFKLLRAIS-AERQLTLADAGRLYAQGVLTPQIAGTAA 370 F DA L ++ S + + +L R + RQL G V TPQI Sbjct: 318 FDPDAALPEIPETNASKSSRERVIELARNENLTVRQLAQRLGGYSGLAFVGTPQI----- 372 Query: 371 DVADWLQSIIVANGADGFVISPSHLPYGFDDFVDQVIPELQRRGAFRQDYAGRQLRQHL 429 +AD ++ +V G+DGF I +LP G DDFV++V+PELQRRG FR+ Y G LR++L Sbjct: 373 -IADEMEKWLVTEGSDGFNIMFPYLPAGLDDFVEKVVPELQRRGIFRRQYEGSTLRENL 430