BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0291.p (476 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGpA571 [GEPR] COG0477 Permeases of the major facilitator superf... 152 2e-36 PA3467 [GEPR] COG0477 Permeases of the major facilitator superfa... 140 9e-33 RSp0052 [GEPR] COG0477 Permeases of the major facilitator superf... 120 1e-26 SSO3143 [GEPR] COG0477 Permeases of the major facilitator superf... 120 1e-26 PAE2330 [GEPR] COG0477 Permeases of the major facilitator superf... 119 1e-26 TVN0436 [GEPR] COG0477 Permeases of the major facilitator superf... 119 1e-26 DRA0271 [GEPR] COG0477 Permeases of the major facilitator superf... 116 1e-25 Ta0334 [GEPR] COG0477 Permeases of the major facilitator superfa... 115 2e-25 Cgl2919 [GEPR] COG0477 Permeases of the major facilitator superf... 115 3e-25 Z2813 [GEPR] COG0477 Permeases of the major facilitator superfam... 113 9e-25 >AGpA571 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 461 Score = 152 bits (383), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 143/485 (29%), Positives = 228/485 (47%), Gaps = 60/485 (12%) Query: 5 ASLPARLDRLPWSR---WHWRVVIALGVAWVLDGLEVTLVGSIGSVLERPDTLGLDAAQV 61 A + ARL+RLP +R W +V G A DG V + VL R GL +Q Sbjct: 19 ADISARLERLPITREVFWARNIV---GAATFFDGYTVIAIAYAMPVLVR--EWGLTPSQT 73 Query: 62 GWTGSLYIAGAVVGALVFGRLTDRLGRKKLFMITLALYMAATLASAFATDFLWFALCRLA 121 G S+ G ++GA++FG L +R+GR K+ + T+ L+++ +A FA R Sbjct: 74 GMILSMGYLGQLIGAILFGWLAERIGRLKVLLFTILLFVSMDVACLFAAGAGMMMAFRFV 133 Query: 122 TGLGIGGEYAAINSAIDELVPARVRGRVNLVINASFWIGAALGAGLSLVILDERVLGPVM 181 G+G GGE ++ I+EL+ ++ RGR L+ F +G +GAG L + P+ Sbjct: 134 QGIGTGGEVPVASAYINELIGSKGRGRFFLLYEVMFLLG-LVGAG-----LIGYFMVPLY 187 Query: 182 GWRVCFLLGAVLAVAIVLVRRHVPESPRWLAMHGHHARAEAVVREIEAQVMAEHGTLPAL 241 GW+ F++G V A+ ++ +R + ESPRWLA G + A +V+ +E A LP Sbjct: 188 GWKAMFIVGLVPAMLMIPLRWFLKESPRWLAATGRYDEANVIVKRMEESARAAGKALP-- 245 Query: 242 PTAAPGEPSRSPGQAAGLLSWREIAQVLLHHYRARSLMVALMMVAQAFVYNAIFFTYSLV 301 EP A + WRE+ Q + Y R+L + M V N + Sbjct: 246 ------EPRIIATPAKRVSDWRELFQGI---YLKRTLSIWAMWFCAYMVANGTITWLPTL 296 Query: 302 LTRFFQVPDTRVALYLFPFALGNVLGPLLLGHLFDSIGRRRMIAATYLLAGLGLAATAAA 361 + F +P LY F + V+ ++ L D +GR+R A LLA + LA A Sbjct: 297 YRQTFNLPLETSILYGFMTSAAGVVAAVICALLIDKVGRKRWYAGALLLAPVPLAILA-- 354 Query: 362 FNAGWLDA---LGLALCWSAVFFVASAAASSAYLTASEVFPLQMRAMAIAIFYAIGTG-- 416 WL A + + + + + S YL ++E++P +MR AIGTG Sbjct: 355 ----WLGATSPMQVLIFAGLAYAIVQTVTFSLYLYSAEIYPTRMR--------AIGTGAG 402 Query: 417 -----VGGFIAPALLGWLIASGERQAVAAGYA----VGAVLALLAGLCALRWAVDAERRT 467 +G P L+G++++S Q V A +A +GAV+ +L +AV+ + + Sbjct: 403 SAWLRLGSSAGPMLVGFVMSSMGIQYVFATFAFILIIGAVVTML-------FAVETKGKV 455 Query: 468 LEEVA 472 LEE++ Sbjct: 456 LEELS 460 >PA3467 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 455 Score = 140 bits (352), Expect = 9e-33, Method: Compositional matrix adjust. Identities = 140/479 (29%), Positives = 223/479 (46%), Gaps = 35/479 (7%) Query: 2 SAAASLPARLDRLPWSRWHWRVVIALGVAWVLDGLEVT----LVGSIGSVLERPDTLGLD 57 A AS RL+RLP S +H V + + +A+ D +++ L+GSI + GLD Sbjct: 3 DAPASAAERLERLPLSPYHRLVFVIIALAFFFDSMDLAMMTFLLGSIKA------EFGLD 56 Query: 58 AAQVGWTGSLYIAGAVVGALVFGRLTDRLGRKKLFMITLALYMAATLASAFATDFLWFAL 117 +AQ G S G V+GA + G L DR GRK +F ++ L+ A+ + A D Sbjct: 57 SAQAGLLASSSFFGMVIGAALSGMLADRFGRKPVFQASIVLWGLASYLCSTAGDLDSLTF 116 Query: 118 CRLATGLGIGGEYAAINSAIDELVPARVRGRVNLVINASFWIGAALGAGLSLVILDERVL 177 R+ G+G+G E+ S + E++PA RG+ +++ + +G LS +L Sbjct: 117 YRVLLGIGMGMEFPIAQSLLSEMIPASRRGKYIALMDGFWPLGFVAAGCLSYFLL----- 171 Query: 178 GPVMGWRVCFLLGAVLAVAIVLVRRHVPESPRWLAMHGHHARAEAVVREIEAQVMAEHG- 236 P+ GWR FL+ A+ AV ++ +R +PESPRWL G +A+ V+R+IEA+VM G Sbjct: 172 -PLTGWRSIFLVLALPAVFVLAIRFLIPESPRWLEQAGRREQADRVLRDIEARVMRSLGL 230 Query: 237 -TLPALPTAAPGEPSRSPGQAAGLLSWREIAQVLLHHYRARSLMV-ALMMVAQAFVYNAI 294 LP P P PG + A++ YR R+L V L A Y Sbjct: 231 TELPP-PLRQPQRERSRPG------FFSAFAELWSPAYRRRTLTVWGLWFFALLGFYGLT 283 Query: 295 FFTYSLVLTRFFQVPDTRVALYLFPFALGNVLGPLLLGHLFDSIGRRRMIAATYLLAGLG 354 + +L+ F V T+ Y +L + G L L +S GR+ + +L G G Sbjct: 284 SWLSALLQQSGFAV--TQSVYYTVLISLAGIPGFLCAAWLVESWGRKP--SCVLMLLGGG 339 Query: 355 LAATAAAFNAGWLDALGLALCWS-AVFFVASAAASSAYLTASEVFPLQMRAMAIAIFYAI 413 A A A + +L L + + A+ F + Y E++P RA A+ Sbjct: 340 AMAYAYGQTAVFGGSLALLIGFGLAMQFFLFGMWAVLYTYTPELYPTSARATGSGFASAV 399 Query: 414 GTGVGGFIAPALLGWLIASGERQAVAAGYAVGAVLALLAGLCALRWAVDAERRTLEEVA 472 G +G + P + G ++ + V + +GA+ +A L + ++ RTLEE+A Sbjct: 400 GR-IGSLLGPLVTGLVLPLTGQGGV---FTLGALCFGVAALVVWAFGIETRGRTLEELA 454 >RSp0052 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 476 Score = 120 bits (300), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 114/347 (32%), Positives = 171/347 (49%), Gaps = 24/347 (6%) Query: 10 RLDRLPWSRWHWRVVIALGVAWVLDGLEV-TLVGSIGSVLERPDTLGLDAAQVGWTGSLY 68 RL+RLP+S +H R+ I + +A+ D +++ T+ +GS+ + GL A G S Sbjct: 16 RLERLPFSGYHKRIFIIIAIAFFFDSVDLATMTFVLGSIKKE---FGLSTATAGLVASSS 72 Query: 69 IAGAVVGALVFGRLTDRLGRKKLFMITLALYMAATLASAFATDFLWFALCRLATGLGIGG 128 G V+GA V G L DR GR+ +F ++ L+ A+ + A R+ G+G+G Sbjct: 73 FFGMVIGAAVAGLLADRFGRRPVFQWSMVLWGVASYLCSTAQSVEALIAWRILLGIGMGM 132 Query: 129 EYAAINSAIDELVPARVRGRVNLVINASFWIGAALGAGLSLVILDERVLGPVMGWRVCFL 188 E+ + + E VP RGR+ +++ FW + AG I+ VL P GWR F Sbjct: 133 EFPVAQTLLSEFVPTANRGRLIALMDG-FWPLGFITAG----IVSYFVL-PQFGWRAVFA 186 Query: 189 LGAVLAVAIVLVRRHVPESPRWLAMHGHHARAEAVVREIEAQVMA--EHGTLPALPTAAP 246 L AV A+ +++VRR VPESPRWL G +A+A+ V+R IEA+VM TLP + + Sbjct: 187 LLAVPAIFVLIVRRAVPESPRWLEHAGRNAQADTVMRGIEAKVMRSLNTTTLPPIVQHSA 246 Query: 247 GEPSRSPGQAAGLLSWREIAQVLLHHYRARSLMVALM-MVAQAFVYNAIFFTYSLVLTRF 305 +P R + REI YR R+ MV L+ A Y + +L+ Sbjct: 247 PQPVRRHS------ALREIWSA---AYRRRTTMVWLLWFFALLGFYGLTSWLGALLQQAG 297 Query: 306 FQVPDTRVALYLFPFALGNVLGPLLLGHLFDSIGRRRMIAATYLLAG 352 F V T+ Y +LG V G L L + GR+ A+ L G Sbjct: 298 FAV--TQSVYYTVLISLGGVPGFLCAAWLVERWGRKPTCIASLLGGG 342 >SSO3143 [GEPR] COG0477 Permeases of the major facilitator superfamily Sso Sulfolobus solfataricus Length = 448 Score = 120 bits (300), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 116/477 (24%), Positives = 222/477 (46%), Gaps = 39/477 (8%) Query: 6 SLPARLDRLPWSRWHWRVVIALGVAWVLDGLEVTLVGSIGSVLERPDTLGLDAAQVGWTG 65 S+ R++RLPW+ +H R++ L + + ++ G + S + + A + +T Sbjct: 2 SIAGRIERLPWTSFHTRLLAILTLGEFFELYDLFTGGFVASQIASFYKVS-SATGIYYTV 60 Query: 66 SLYIAGAVVGALVFGRLTDRLGRKKLFMITLALYMAATLASAFATDFLWFALCRLATGLG 125 +++ GA VGA++F + D +GR+ +I + + A L F+ + L + R G+G Sbjct: 61 AIFFLGAFVGAIIFNYIGDSVGRRTALIINMTITSIALLLIPFSPNILTLGILRFLAGVG 120 Query: 126 IGGE-YAAINSAIDELVPARVRGRVNLVINASFWIGAALGAGLSLVILDERVLGPVMGWR 184 +G E ++ + E P+ VRG+ + W + A L+ +L + + GW+ Sbjct: 121 VGPEAILVLDVLVTEFFPSNVRGKALAIGYTIAWTAPIVVAVLAYFLLPHKYF--LYGWQ 178 Query: 185 VCFLLGAVLAVAIVLVRRHVPESPRWLAMHGHHARAEAVVREIEAQVMAEHGTLPALPTA 244 F++G + + I+ R +PESPRWL G AE VR++E + E G L Sbjct: 179 WLFIIGGLGILTIIPFRFLIPESPRWLESKGRLDEAEKTVRKMEEIAIKEKGQL------ 232 Query: 245 APGEPSRSPGQAAGLLSWR-EIAQVLLHHYRARSLMVALMMVAQAFVYN-------AIFF 296 GEP Q + S R +I+++ YR R++M+ + QA VY ++ F Sbjct: 233 --GEPI----QVQVITSQRVKISELFSPLYRKRTVMLWIFEFLQAGVYYGFASLAPSVLF 286 Query: 297 TYSLVLTRFFQVPDTRVALYLFPFALGNVLGPLLLGHLFDSIGRRRMIAATYLLAGLGLA 356 L Q Y F +L ++ ++ FD R+ ++ LL +GL Sbjct: 287 AKGFTLVHTLQYTMIIYTSY-FISSLASIF--IIDSQKFD---RKWQVSIVMLL--MGLV 338 Query: 357 ATAAAFNAGWLDALGLALCWSAVFFVASAAASSAYLTASEVFPLQMRAMAIAIFYAIGTG 416 A F++ L+A+ + F+++ +++ + +E++P ++RA A + Y++ + Sbjct: 339 GLAFGFSSSPLEAVVTGFTFG---FLSNIFSNAFHQYGAELYPTRVRAFADGVQYSL-SR 394 Query: 417 VGGFIAPALLGWLIASGERQAVAAGYAVGAVLALLAGLCALRWAVDAERRTLEEVAE 473 +G +I LL ++ S A Y + ++AL+ L A + LEE+++ Sbjct: 395 LGNYIWLTLLPIVLYS---NGPVAMYTIVFIMALIVTLDVAILGPKASKIELEELSK 448 >PAE2330 [GEPR] COG0477 Permeases of the major facilitator superfamily Pya Pyrobaculum aerophilum Length = 384 Score = 119 bits (299), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 73/197 (37%), Positives = 109/197 (55%), Gaps = 10/197 (5%) Query: 22 RVVIALGVAWVLDGLEVTLVGSIGSVLERPDTLGLDAAQVGWTGSLYIAGAVVGALVFGR 81 R+V+ G+ W+ D L+V ++ + ++ + L LD+ W G ++GA++FGR Sbjct: 5 RLVLYTGLGWMFDALDVLILSYL--LVAMSNELKLDSQAKNWIVLANNLGMLIGAMLFGR 62 Query: 82 LTDRLGRKKLFMITLALYMAATLASAFATDFLWFALCRLATGLGIGGEYAAINSAIDELV 141 L DR+GRKK+FM TL Y AT SAFA ++ FA+ R GLG+GGE + + + E Sbjct: 63 LADRVGRKKVFMSTLLTYSIATAISAFARNWQEFAVIRFFVGLGLGGELPVVATYVSENS 122 Query: 142 PARVRGRVNLVINASFW-IGAALGAGLSLVILDERVLGPVMGWRVCFLLGAVLAVAIVLV 200 P RGR N+V+ SFW +GA L A +SL + +GWR LL A + ++ Sbjct: 123 PPERRGR-NVVLLESFWSLGAILAAAISLFLFT------TIGWRSSLLLMGATAFYVFVI 175 Query: 201 RRHVPESPRWLAMHGHH 217 R +PES RWL + Sbjct: 176 RFTLPESQRWLELREQR 192 >TVN0436 [GEPR] COG0477 Permeases of the major facilitator superfamily Tvo Thermoplasma volcanium Length = 445 Score = 119 bits (299), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 66/220 (30%), Positives = 114/220 (51%), Gaps = 7/220 (3%) Query: 11 LDRLPWSRWHWRVVIALGVAWVLDGLEVTLVGSIGSVLERPDTLGLDAAQVGWTGSLYIA 70 +DR+ +H ++ I + LDG +++++ ++L P L Sbjct: 7 MDRMGIRPFHRKIEILASMGMFLDGYDLSVITM--AILLMPTQLHFGKLDYILVNVSAFI 64 Query: 71 GAVVGALVFGRLTDRLGRKKLFMITLALYMAATLASAFATDFLWFALCRLATGLGIGGEY 130 G ++GA + GRL+DR+GRKK+F I L L++ + + AT+F + RL G+GIGG+Y Sbjct: 65 GMIIGAPLLGRLSDRIGRKKIFGIDLLLFVVFAITAGLATNFAMLFISRLMLGIGIGGDY 124 Query: 131 AAINSAIDELVPARVRGRVNLVINASFWIGAALGAGLSLVILDERVLGPVMGWRVCFLLG 190 ++ + E P RG + + +W+G+ A ++ P WR F++G Sbjct: 125 PISSTMVSEFSPVSKRGTLLYGMVGMYWLGSFFSAVMNYTF----AFTPYF-WRYTFIVG 179 Query: 191 AVLAVAIVLVRRHVPESPRWLAMHGHHARAEAVVREIEAQ 230 V+A+ I+ +R +PESPRWL HG AE+VV ++ + Sbjct: 180 GVIAIPIIFLRMRIPESPRWLIGHGMTKSAESVVEDLTGR 219 >DRA0271 [GEPR] COG0477 Permeases of the major facilitator superfamily Dra Deinococcus radiodurans Length = 454 Score = 116 bits (291), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 144/478 (30%), Positives = 211/478 (44%), Gaps = 57/478 (11%) Query: 11 LDRLPWSRWHWRVVIALGVAWVLDGLEVTLVG----SIGSVLERPDTLGLDAAQVGWTGS 66 LD L R+ W+++ G+ W D +EV L+G I + E P G AA + T + Sbjct: 19 LDDLGLGRFQWKLLAICGLTWAADAMEVLLMGFALPGISAAFELPK--GSPAATMLLTAT 76 Query: 67 LYIAGAVVGALVFGRLTDRLGRKKLFMITLALYMAATLASAFATDFLWFALCRLATGLGI 126 AG + GA +G L DR+GR+ +F+ T+AL + LA A A W + R TG I Sbjct: 77 F--AGMLFGAWFWGYLADRVGRRSVFLTTVALGVVFGLAGALAPTLTWLLVARFLTGFAI 134 Query: 127 GGEYAAINSAIDELVPARVRGRVNLVINASFW-IGAALGAGLSLVILDERVLGPVMGWRV 185 GG S + E VP RGR LV SFW +G + A L+ + P GWR Sbjct: 135 GGTLPVDYSMMAEFVPTAWRGRF-LVYLESFWAVGTVVVAALAWWV--STAFAPAEGWRW 191 Query: 186 CFLLGAVLAVAIVLVRRHVPESPRWLAMHGHHARAEAVVREIEAQVMAEHGTLPALPTAA 245 L A+ + ++ R +P+SPR L G A+A A ++++ A GTLPA P A Sbjct: 192 LLGLAALPGLVGLIARIGIPDSPRSLLARGEEAQARAALQKV---AQANGGTLPAAPLAH 248 Query: 246 PGEPSR-SPGQA-AGLLSWREIAQVL------LHHYRARSLMVALMMVAQAFVYNAIFFT 297 P +P R SP Q G+L+ R ++ L +Y S + + + AQ A++ Sbjct: 249 PEQPPRVSPAQLFRGVLARRTPLLMVTWFGLSLGYYGIFSWLPSFLR-AQGLDLGAVY-- 305 Query: 298 YSLVLTRFFQVPDTRVALYLFPFALGNVLGPLLLGHLFDSIGRRRMIAATYLLAGLGLAA 357 R L L AL V G LL +L + IGRR L+ L L A Sbjct: 306 --------------RSTLLL---ALAQVPGYLLAAYLVEKIGRR-----VTLVGFLTLGA 343 Query: 358 TAAAFNAGWLDALGLALCWSAVFFVASAAASSAYLTASEVFPLQMRAMAIAIFYAIGTGV 417 A DA + L + + F A S Y E+FP +R + + + + Sbjct: 344 VGAYLFLLAHDANTVLLTSALLSFALLGAWGSLYAYTPELFPTPLRTTGMGLVSGVAR-L 402 Query: 418 GGFIAPALLGWLIASGERQAVAAGYAVGAVLALLAGLCALRWAVDAERR--TLEEVAE 473 ++P+ +G ++ +G +AV LA LA W + E R L E AE Sbjct: 403 ASVVSPS-IGAMLLTGNLTLALTVFAVCFALAALAA-----WGIGVETRGQALAETAE 454 >Ta0334 [GEPR] COG0477 Permeases of the major facilitator superfamily Tac Thermoplasma acidophilum Length = 445 Score = 115 bits (289), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 62/221 (28%), Positives = 111/221 (50%), Gaps = 7/221 (3%) Query: 10 RLDRLPWSRWHWRVVIALGVAWVLDGLEVTLVGSIGSVLERPDTLGLDAAQVGWTGSLYI 69 +D + +H ++ I + LDG +++++ ++L P L + + Sbjct: 6 EMDNMRMRPFHRKMEILASMGMFLDGYDLSVIAM--AILLMPIQLKFSKPEYILVNVSAL 63 Query: 70 AGAVVGALVFGRLTDRLGRKKLFMITLALYMAATLASAFATDFLWFALCRLATGLGIGGE 129 AG +VGA + GRL+DR+GRKK+F I L L++ + + AT+F + R G+GIGG+ Sbjct: 64 AGMIVGAPLLGRLSDRIGRKKIFDIDLILFVVFAITAGLATNFWMMFISRFMLGVGIGGD 123 Query: 130 YAAINSAIDELVPARVRGRVNLVINASFWIGAALGAGLSLVILDERVLGPVMGWRVCFLL 189 Y ++ + E P + RG + + +W+G+ I++ WR F++ Sbjct: 124 YPISSTIVSEFAPVKRRGTLLYAMVGMYWLGSLFSG-----IMNYTFAFTYYFWRYTFII 178 Query: 190 GAVLAVAIVLVRRHVPESPRWLAMHGHHARAEAVVREIEAQ 230 G ++A+ I+ +R +PESPRWL G A V+ I + Sbjct: 179 GGIVAIPIISLRMQIPESPRWLVSQGRADEASKVIENITGK 219 >Cgl2919 [GEPR] COG0477 Permeases of the major facilitator superfamily Cgl Corynebacterium glutamicum Length = 439 Score = 115 bits (287), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 77/215 (35%), Positives = 115/215 (53%), Gaps = 6/215 (2%) Query: 10 RLDRLPWSRWHWRVVIALGVAWVLDGLEVTLVGSIGSVLERPDTLGLDAAQVGWTGSLYI 69 RLDRLP + H +++ G+ W LD ++V L+ + + L GL + GS+ Sbjct: 8 RLDRLPVTSKHKKILGGSGIGWALDAMDVGLISFVMAALA--THWGLSPTETSLLGSIGF 65 Query: 70 AGAVVGALVFGRLTDRLGRKKLFMITLALYMAATLASAFATDFLWFALCRLATGLGIGGE 129 G +GA + G L D+LGR+++F ++L +Y AT ASA + R GLG+G E Sbjct: 66 VGMAIGASLGGLLADKLGRRQVFALSLLVYGVATGASALSVSLAMLMALRFVVGLGLGAE 125 Query: 130 YAAINSAIDELVPARVRGRVNLVINASFWIGAALGAGLSLVILDERVLGPVMGWRVCFLL 189 ++ I E P +VRGR+ +++ A FW ALG ++ ++ V G GWR L Sbjct: 126 LPVASTLISEFSPRKVRGRMVVILEA-FW---ALGWIMAAIVGTFVVAGSDNGWRWALAL 181 Query: 190 GAVLAVAIVLVRRHVPESPRWLAMHGHHARAEAVV 224 G V A+ V VR +PES R+L G H AEA+V Sbjct: 182 GCVPAIYAVYVRLGLPESVRFLEKKGRHDEAEAIV 216 >Z2813 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 459 Score = 113 bits (283), Expect = 9e-25, Method: Compositional matrix adjust. Identities = 104/344 (30%), Positives = 163/344 (47%), Gaps = 32/344 (9%) Query: 9 ARLDRLPWSRWHWRVVIALGVAWVLDGLEVTLVGSIGS-VLERPDTLG-LDAAQVGWTGS 66 ARLDRLP RWH + A V GL V ++G +L + LG D + + Sbjct: 11 ARLDRLPDCRWHSSMF-----AIVAFGLLVCWSNAVGGLILAQLKALGWTDNSTTATFSA 65 Query: 67 LYIAGAVVGALVFGRLTDRLGRKKLFMITLALYMAATLASAFATDFLWFALCRLATGLGI 126 + AG +GALV G + D+ GR+ F++ A+++A+ + AF+ + + CR G+G+ Sbjct: 66 ITTAGMFLGALVGGIIGDKTGRRNAFILYEAIHIASMVVGAFSPNMDFLIACRFVMGVGL 125 Query: 127 GGEYAAINSAIDELVPARVRG----RVNLVINASFWIGAALGAGLSLVILDERVLGPVMG 182 G + + E +P R RG RV+ + N S+ + + + GL+ +I E Sbjct: 126 GALLVTLFAGFTEYMPGRNRGTWSSRVSFIGNWSYPLCSLIAMGLTPLISAE------WN 179 Query: 183 WRVCFLLGAVLA-VAIVLVRRHVPESPRWLAMHGHHARAEAVVREIEAQVMAEHGT-LPA 240 WRV L+ A+L+ +A L R+ PESPRWL G + AE V+R IE V+ G LP Sbjct: 180 WRVQLLIPAILSLIATALAWRYFPESPRWLESRGRYQEAEKVMRSIEEGVIRHTGKPLPP 239 Query: 241 LPTAAPGE-PSRSPGQAAGLLSWREIAQVLLHHYRARSLMVALMMVAQAFVYNAIFFTYS 299 + A G+ P P A + VLL S ++ M V Q Y I + + Sbjct: 240 VVIADDGKAPQAVPYSAL-------LTGVLLKRVILGSCVLIAMNVVQ---YTLINWLPT 289 Query: 300 LVLTRFFQVPDTRVALYLFPFALGNVLGPLLLGHLFDSIGRRRM 343 + +T+ + D+ V + F G G + + D I R+ M Sbjct: 290 IFMTQGINLKDSIVLNTMSMF--GTPFGIFIAMLVMDKIPRKTM 331