BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0022.0281.p         (287 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

TP0696 [Q] COG1335 Amidases related to nicotinamidase Tpa Trepon...   121   2e-27
alr5162 [Q] COG1335 Amidases related to nicotinamidase Nos Nosto...    87   3e-17

>TP0696 [Q] COG1335 Amidases related to nicotinamidase Tpa Treponema
           pallidum
          Length = 278

 Score =  121 bits (304), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 87/281 (30%), Positives = 130/281 (46%), Gaps = 26/281 (9%)

Query: 7   LLVIDPQNDFCDLPASWLPVDPAGGGALQPALPVAGSHADLQRVAGLIDQGGAGLSAISI 66
             ++D QNDFCD         P G      AL V G+  D  RVA  +    A + A+ +
Sbjct: 5   FFLVDFQNDFCD---------PRG------ALFVPGADQDCVRVAEFLRVHAAHVDALYV 49

Query: 67  TLDAHHRLDIAHPTFWRQGDGSAVTPFTQIEAAQVRAGLYLPRDPQSLPRALAYLDALEA 126
           + D H R+ +AHP FWR   G A+ PF  +   ++R+G  +P     +     YL     
Sbjct: 50  SCDRHPRMHVAHPCFWRSLTGDALGPFDTVSFERLRSGACVPVRVGYVQTVAGYLAFRAY 109

Query: 127 AGRYRLMVWPVHCEIGSWGAAVHADVRAAYNRWEE--RTLGVVTKLGKGSNPWTEHYSAV 184
            G+  L +WP HC  GSWG AVH  +  A   W+   RT        KG NP  E +S +
Sbjct: 110 TGKGPLYLWPEHCVRGSWGQAVHPLIVEAVRFWQRAHRTRH-PQFFFKGENPCVEQFSVL 168

Query: 185 MAEVPDDDDPATQLNRGFIATLAQADTVYITGEAGSHCVRATTEHIAANLDAAG-RARLV 243
            +E P     A  L       L   + +++ GEA SHCV  T +    ++  AG  +R+ 
Sbjct: 169 SSEYPASQGTADSLFVKRCQMLRAHERIFVAGEALSHCVVCTLQ----DMQRAGVLSRVS 224

Query: 244 LVTDCMSPVAGFEAQYQDFLAAMSQAG---VRLATSAQVLQ 281
           L+ D  S V GFE +    +  +   G   +R+  +A++L+
Sbjct: 225 LLKDGSSVVPGFEQKTAASVQTLCAQGLTWLRMTEAAELLR 265


>alr5162 [Q] COG1335 Amidases related to nicotinamidase Nos Nostoc sp. PCC
           7120
          Length = 343

 Score = 87.4 bits (215), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 79/268 (29%), Positives = 112/268 (41%), Gaps = 37/268 (13%)

Query: 2   KRSLHLLVIDPQNDFCDLPASWLPVDPAGGGALQPALPVAGSHADLQRVAGLIDQGGAGL 61
           K  + LL+ID QN FC +P   L V    G          G+  D +R+   I      +
Sbjct: 45  KIRICLLLIDVQNTFC-IPEFELFVGGESG---------TGAVDDNRRICEFIYHNLGLI 94

Query: 62  SAISITLDAHHRLDIAHPTFWRQGDGSAVTPF-TQIEAAQVRAGLYLPR----------D 110
           + I  TLD H    I HP FW        TP  T I    +  G++             D
Sbjct: 95  TKIIPTLDTHTATQIFHPIFWVNESSEHPTPAATSITLTDIEKGIWKVNPDVANSITHGD 154

Query: 111 PQSLPR-ALAYLDALEAAGRYRLMVWPVHCEIGSWGAAVHADVRAAYN-----RWEERTL 164
            + L + A  Y+  L   G+Y L VWP H  +G  G A+ + V  A       R  +   
Sbjct: 155 YELLEKHAYHYVKQLSQDGKYPLTVWPYHSMLGGIGHALVSAVEEAIFFHGIARHSQTQF 214

Query: 165 GVVTKLGKGSNPWTEHYSAVMAEV--PDDDDPATQLNRGFIATLAQADTVYITGEAGSHC 222
            +     KG NP TE+YS +  EV    D++P    N+  I  L + D V I G+A SHC
Sbjct: 215 EI-----KGDNPLTENYSVLRPEVLIGFDENPLADKNQKLIKQLLEFDAVIIAGQAKSHC 269

Query: 223 VRATTEHIAANL---DAAGRARLVLVTD 247
           V  T + +   +   D A   ++ L+ D
Sbjct: 270 VAWTIDDLLTEIQQVDTALAKKVYLLED 297