BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0219.p (524 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BMEII0052 [T] COG0642 Signal transduction histidine kinase Bme B... 179 1e-44 AGl216 [T] COG0642 Signal transduction histidine kinase Atu Agro... 168 3e-41 mll0989_2 [T] COG0642 Signal transduction histidine kinase Mlo M... 156 1e-37 SMb20868_3 [T] COG0642 Signal transduction histidine kinase Sme ... 155 3e-37 CC0759_2 [T] COG0642 Signal transduction histidine kinase Ccr Ca... 150 5e-36 AGl1117_2 [T] COG0642 Signal transduction histidine kinase Atu A... 150 6e-36 mll0984_3 [T] COG0642 Signal transduction histidine kinase Mlo M... 149 1e-35 SMa0939 [T] COG0642 Signal transduction histidine kinase Sme Sin... 147 5e-35 mll6607_2 [T] COG0642 Signal transduction histidine kinase Mlo M... 135 3e-31 mlr7238 Non COG 120 1e-26 >BMEII0052 [T] COG0642 Signal transduction histidine kinase Bme Brucella melitensis Length = 355 Score = 179 bits (455), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 95/239 (39%), Positives = 148/239 (61%) Query: 283 EYAIRAAQIDMERVSRANTVGQLTASIAHEINQPLMSIVANAGASLRWLDRAVPDLEHAR 342 E +R ++ + R++R T+GQLT+SIAHE++QPL++I +A A RWL ++ P+ E A Sbjct: 110 EIDVRESRERLLRLARMTTLGQLTSSIAHEVSQPLVAIEISASAGRRWLAQSPPNNERAA 169 Query: 343 TGLRDIIAEGQRAGGIISGLRDLTRNAAPVCERVNLHAVIRHILTLSRSELERREVSLLL 402 + I + RA I+ +R L+R P +++ V+R I+ L+ +E+ R +++L L Sbjct: 170 AAIERISVDSHRAIEILDRVRRLSRGEKPHVAPFDINEVVRDIVELAHNEITRHDIALDL 229 Query: 403 SLTPADAFVLGDQVQLQQVMLNLVVNAIEAMSGMPEHARVLSITASSCDEQRIEVRVQDS 462 LTP L D+VQ+QQV+ NLV+NAIEA+ R L I + + R++V V+DS Sbjct: 230 DLTPGLPMALADRVQIQQVIGNLVLNAIEAIQEKDPPVRSLKINTALTEGARLQVAVRDS 289 Query: 463 GEGIAPEAMRRVFDAFYTTKDSGMGMGLAICRSIIENHRGRLRVAAAQPHGALFSFDLP 521 G GIAP R+FDAF+TTK G G+GL I R+I+E+ G + + + PHG F++P Sbjct: 290 GGGIAPADQERLFDAFWTTKKGGFGLGLTISRTIVESSGGTIALGSTTPHGTTILFEVP 348 >AGl216 [T] COG0642 Signal transduction histidine kinase Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 526 Score = 168 bits (425), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 100/281 (35%), Positives = 154/281 (54%), Gaps = 3/281 (1%) Query: 242 ICRQDTGEVR-YLSGIGKPIWRDGTFTEYVGTATDITVRRQNEYAIRAAQIDMERVSRAN 300 + R D+GE + L I P +F V + D+T R A+ AQ ++ + S+A Sbjct: 240 VVRTDSGEDKLVLLSISFPA-EAASFNRVVVSMVDVTQREMELKALAEAQAELTKASKAA 298 Query: 301 TVGQLTASIAHEINQPLMSIVANAGASLRWLDRAVPDLEHARTGLRDIIAEGQRAGGIIS 360 VG ++AS++HE+NQPL +I+ NA LRWLDR PDL AR +I +G+RA II Sbjct: 299 AVGAMSASLSHELNQPLGAIIVNAQTLLRWLDRDPPDLAAARRSAERMIRDGERASDIIQ 358 Query: 361 GLRDLTRNAAPVCERVNLHAVIRHILTLSRSELERREVSLLLSLTPADAFVLGDQVQLQQ 420 R L + + E +L I L+L ELER ++ + A + +++LQQ Sbjct: 359 NTRSLLAHTSGKVETFDLDEFIDETLSLLEHELERSGTTVHVE-NEATPPITAVRIELQQ 417 Query: 421 VMLNLVVNAIEAMSGMPEHARVLSITASSCDEQRIEVRVQDSGEGIAPEAMRRVFDAFYT 480 V++NL+ NAI+AM R +++ D I++ V+DSG G + ++F F+T Sbjct: 418 VLINLLTNAIQAMDEAGISNRTITVRKEREDGDNIQIAVEDSGPGFPAQMKDKLFSPFFT 477 Query: 481 TKDSGMGMGLAICRSIIENHRGRLRVAAAQPHGALFSFDLP 521 TK++GMGMGL+ICR+ +E GRL GA+F+ +P Sbjct: 478 TKETGMGMGLSICRTTLEARGGRLTGDNHPLGGAVFTISMP 518 >mll0989_2 [T] COG0642 Signal transduction histidine kinase Mlo Mesorhizobium loti Length = 228 Score = 156 bits (394), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 92/214 (42%), Positives = 121/214 (56%), Gaps = 4/214 (1%) Query: 309 IAHEINQPLMSIVANAGASLRWLDRAVPDLEHARTGLRDIIAEGQRAGGIISGLRDLTRN 368 IAHE+NQPL ++VANAGA RWL P+ +HA + II A +I +R L Sbjct: 1 IAHELNQPLQAVVANAGAFQRWLTADPPNFDHAGRVAQKIIRNADAAAQVIGRIRSLFSK 60 Query: 369 AAPVCERVNLHAVIRHILTLSRSELERREVSLLLSLTPADAFVLGDQVQLQQVMLNLVVN 428 + ++L+A+IR + L L V L L L P D VQ++QV+LNLV N Sbjct: 61 TEGEPQPLDLNALIREVCELMGDRLASSRVMLELDLDPELPATAADHVQMEQVVLNLVRN 120 Query: 429 AIEAMSGMPEHARVLSITASSCDEQRIEVRVQDSGEGIA-PEAMRRVFDAFYTTKDSGMG 487 IEAM + AR L I + D+ +EV V+D G G++ PE R+F+AFYTTK GMG Sbjct: 121 GIEAMQDVSTTARSLRIVSRGQDDGTVEVEVRDRGRGLSDPE---RIFEAFYTTKPDGMG 177 Query: 488 MGLAICRSIIENHRGRLRVAAAQPHGALFSFDLP 521 MGL ICRSI+E H GR+ + GA F LP Sbjct: 178 MGLPICRSIVEAHYGRVWAKNVEGGGASIIFSLP 211 >SMb20868_3 [T] COG0642 Signal transduction histidine kinase Sme Sinorhizobium meliloti Length = 246 Score = 155 bits (391), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 98/247 (39%), Positives = 145/247 (58%), Gaps = 8/247 (3%) Query: 278 VRRQNEYAIRAAQIDMERVSRANTVGQLTASIAHEINQPLMSIVANAGASLRWLDRAVPD 337 VR Q E +R AQ + R +A ++ +L+ASIAHE+NQPL +IVAN+ A RWL + Sbjct: 2 VRMQEE--LRLAQERLARAGQAASLAELSASIAHEVNQPLAAIVANSHACYRWLSADPVN 59 Query: 338 LEHARTGLRDIIAEGQRAGGIISGLRDLTRNAAPVCERVNLHAVIRHILTLSRSELERRE 397 +E A+ +I + + A ++S +R L + + + L VI +L +E RR Sbjct: 60 IERAKITTERVIRDAKSAADVVSRIRALFKQSVENRGILVLSDVISEACSLVAAEALRRR 119 Query: 398 VSLLLSLTPADAFVLGDQVQLQQVMLNLVVNAIEAMSGMPEHARVLSITASSCDEQRIEV 457 + L + + A V D++Q+QQV++NL+ N +EAM + ++ V DE RIE Sbjct: 120 IRLNIDVETNLAPVTVDRIQVQQVLVNLIRNGMEAMDAVDDNKTVDVRMHQVDDEVRIE- 178 Query: 458 RVQDSGEGIA-PEAMRRVFDAFYTTKDSGMGMGLAICRSIIENHRGRLRVAAAQPHGALF 516 + D+G G+A PE R+F+ F+TTK++GMGMGLAI RSI+E H GRL +P GA F Sbjct: 179 -IGDNGNGVAFPE---RIFEPFFTTKENGMGMGLAISRSIVEAHGGRLWAEKNEPRGARF 234 Query: 517 SFDLPRV 523 F LP V Sbjct: 235 VFTLPNV 241 >CC0759_2 [T] COG0642 Signal transduction histidine kinase Ccr Caulobacter vibrioides Length = 244 Score = 150 bits (380), Expect = 5e-36, Method: Compositional matrix adjust. Identities = 92/227 (40%), Positives = 123/227 (54%), Gaps = 1/227 (0%) Query: 296 VSRANTVGQLTASIAHEINQPLMSIVANAGASLRWLDRA-VPDLEHARTGLRDIIAEGQR 354 VSR +G++ +++AHE+NQPL +I S R +DR D R + A+ R Sbjct: 4 VSRLTAMGEMASTLAHELNQPLSAIANLLTGSRRLMDRGREADQAKVRDAIDRAAAQALR 63 Query: 355 AGGIISGLRDLTRNAAPVCERVNLHAVIRHILTLSRSELERREVSLLLSLTPADAFVLGD 414 AG +I +RD R A E +L +I L+ + R+V + L L P V D Sbjct: 64 AGEVIHRMRDFARRGASEREVESLSKLIEEASALALIGEKERQVDVRLKLDPKADDVFAD 123 Query: 415 QVQLQQVMLNLVVNAIEAMSGMPEHARVLSITASSCDEQRIEVRVQDSGEGIAPEAMRRV 474 +VQ+QQV+LNL+ N I+AM R L I +E EV V D+G GIAPE + R+ Sbjct: 124 RVQIQQVLLNLIRNGIDAMQAQEPRKRALLIRTGLTEEGWSEVSVADTGPGIAPEVLERL 183 Query: 475 FDAFYTTKDSGMGMGLAICRSIIENHRGRLRVAAAQPHGALFSFDLP 521 F F TTK GMG+GL+I RSIIE H GR+ A GALF F LP Sbjct: 184 FQPFMTTKPQGMGVGLSISRSIIEAHGGRIWAEANPGGGALFRFTLP 230 >AGl1117_2 [T] COG0642 Signal transduction histidine kinase Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 248 Score = 150 bits (380), Expect = 6e-36, Method: Compositional matrix adjust. Identities = 91/232 (39%), Positives = 136/232 (58%), Gaps = 8/232 (3%) Query: 292 DMERVSRANTVGQLTASIAHEINQPLMSIVANAGASLRWLDRAVPDLEHARTGLRDIIAE 351 ++ R S+A ++ +L+ASIAHE+NQPL +++ + A RWL P++E A+ L I+ Sbjct: 14 NLARSSQAASLAELSASIAHEVNQPLSAVMNYSSACQRWLTAEPPNIERAQKTLERIVQS 73 Query: 352 GQRAGGIISGLRDLTRNAAPVCERVNLHAVIRHILTLSRSELERREVSLLLSLTPADAFV 411 A ++S +R L R + + L AV+R L E RR + + + V Sbjct: 74 ANSAADVVSRIRALFRQSTDKRDSTELGAVVRQARDLLAEEAGRRRIRMTVEGESGLLLV 133 Query: 412 LGDQVQLQQVMLNLVVNAIEAMSGMPEHARVLSITA-SSCDEQRIEVRVQDSGEGIA-PE 469 D+VQ+QQV++NL+ N ++AM+ + + RVL + A + D RIE V D G G+ P+ Sbjct: 134 PFDRVQIQQVLVNLLRNGMDAMASVA-NERVLQVRAFRAGDMVRIE--VADRGRGVQFPD 190 Query: 470 AMRRVFDAFYTTKDSGMGMGLAICRSIIENHRGRLRVAAAQPHGALFSFDLP 521 R+F+ F+TTKD GMGMGLAICRSIIE H G+L +P G+ F F LP Sbjct: 191 ---RIFEPFFTTKDQGMGMGLAICRSIIEAHEGQLWAEKNEPIGSKFVFTLP 239 >mll0984_3 [T] COG0642 Signal transduction histidine kinase Mlo Mesorhizobium loti Length = 255 Score = 149 bits (377), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 90/239 (37%), Positives = 138/239 (57%), Gaps = 4/239 (1%) Query: 283 EYAIRAAQIDMERVSRANTVGQLTASIAHEINQPLMSIVANAGASLRWLDRAVPDLEHAR 342 E A+R A ++ R A ++ +L+ASIAHE+NQPL ++VAN+ A RWL P+++ A+ Sbjct: 14 EEALRRASEELARAMNAASLAELSASIAHEVNQPLAAVVANSNACERWLMAEPPNVQRAQ 73 Query: 343 TGLRDIIAEGQRAGGIISGLRDLTRNAAPVCERVNLHAVIRHILTLSRSELERREVSLLL 402 + II + A ++S +R L + + L V+ TL E R V + + Sbjct: 74 KIVGRIIRDANSAADVVSRIRALFKQSLDARLDTTLGGVVDQARTLMAEEAARSRVPINI 133 Query: 403 SLTPADAFVLGDQVQLQQVMLNLVVNAIEAMSGMPEHARVLSITASSCDEQRIEVRVQDS 462 + + D+VQ+QQV++NL+ N IEAM G+ + + L++ + I+ V D Sbjct: 134 DVERDLPVIALDRVQIQQVLVNLMRNGIEAMDGVGD-PKSLAVRVHRVGDA-IQTEVSDW 191 Query: 463 GEGIAPEAMRRVFDAFYTTKDSGMGMGLAICRSIIENHRGRLRVAAAQPHGALFSFDLP 521 G G+ E + R+F+ F+TTK+ GMGMGLAI RSI+E+H GRL V +P GA F F LP Sbjct: 192 GPGV--EQLDRMFEPFFTTKEQGMGMGLAISRSIVESHGGRLWVEKNEPRGATFIFTLP 248 >SMa0939 [T] COG0642 Signal transduction histidine kinase Sme Sinorhizobium meliloti Length = 633 Score = 147 bits (372), Expect = 5e-35, Method: Compositional matrix adjust. Identities = 92/245 (37%), Positives = 142/245 (57%), Gaps = 2/245 (0%) Query: 279 RRQNEYAIRAAQIDMERVSRANTVGQLTASIAHEINQPLMSIVANAGASLRWLDRAVPDL 338 R E+ R +++ ++++ T G L+ASIAHE+NQPL +I NA + L+R PDL Sbjct: 384 RAAAEFQARHRLLEVIHLNQSATAGALSASIAHELNQPLGAIRINAETAALMLERPNPDL 443 Query: 339 EHARTGLRDIIAEGQRAGGIISGLRDLTRNAAPV-CERVNLHAVIRHILTLSRSELERRE 397 + + L DI + QRAG II +R L R + + + +L+ V+R + + E +RR+ Sbjct: 444 KLIQQILADIRDDDQRAGDIIDRMRGLLRKRSEIDWQEFDLNDVVRSAIHILHPEAQRRD 503 Query: 398 VSLLLSLTPADAFVLGDQVQLQQVMLNLVVNAIEAMSGMPEHARVLSI-TASSCDEQRIE 456 V++ + V D+V +QQV+LNL +NA++AM P R L TA +++E Sbjct: 504 VTVSSVASAQGLPVRADRVHVQQVILNLAINAMDAMLQAPTAERNLMFQTAMVERNEKVE 563 Query: 457 VRVQDSGEGIAPEAMRRVFDAFYTTKDSGMGMGLAICRSIIENHRGRLRVAAAQPHGALF 516 V + D+G GI + + +FDAFYTTK +G G+GL+I R IIE + G+L GA+F Sbjct: 564 VSISDTGSGIPSDKLSNIFDAFYTTKPTGTGLGLSIARVIIEIYGGKLWADNRPQGGAVF 623 Query: 517 SFDLP 521 F LP Sbjct: 624 RFVLP 628 >mll6607_2 [T] COG0642 Signal transduction histidine kinase Mlo Mesorhizobium loti Length = 240 Score = 135 bits (339), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 89/231 (38%), Positives = 132/231 (57%), Gaps = 13/231 (5%) Query: 296 VSRANTVGQLTASIAHEINQPLMSIVANAGASLRWLDRAVPDLEHARTGLRDIIA----E 351 ++R +G++ +++AHEINQPL +I S R L+++ E+A LRD + + Sbjct: 4 MARFTALGEMASTLAHEINQPLTAITNYLKGSRRLLEKS--QDENAPM-LRDAVERAAEQ 60 Query: 352 GQRAGGIISGLRDLTRNAAPVCERVNLHAVIRHILTLSRSELERREVSLLLS--LTPADA 409 RAG +I LRD + L +I +L+ + RE++LL+S L PA Sbjct: 61 ALRAGDVIRHLRDFVARGESERQVERLPVLIEEAASLAL--VGAREINLLVSYKLDPAAE 118 Query: 410 FVLGDQVQLQQVMLNLVVNAIEAMSGMPEHARVLSITASSCDEQRIEVRVQDSGEGIAPE 469 VL D++Q+QQV+LNL+ NA+EAM G P R L +T + D+ EV V D+G G+APE Sbjct: 119 LVLTDRIQIQQVLLNLMRNAVEAMQGSPR--RELKVTTVARDDGMAEVSVIDTGPGLAPE 176 Query: 470 AMRRVFDAFYTTKDSGMGMGLAICRSIIENHRGRLRVAAAQPHGALFSFDL 520 ++F F TTK GMG+GL+ICR+I+E+H G + A G F F L Sbjct: 177 VSAQLFQPFVTTKKHGMGVGLSICRTIVESHGGHIWAEAIPAGGTAFRFTL 227 >mlr7238 Non COG Length = 601 Score = 120 bits (300), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 77/254 (30%), Positives = 133/254 (52%), Gaps = 5/254 (1%) Query: 270 VGTATDITVRRQNEYAIRAAQIDMERVSRANTVGQLTASIAHEINQPLMSIVANAGASLR 329 + A +I R E +R + D+ + +R + +GQ+ A +AHEINQP+ +I A + R Sbjct: 352 IALAGEIAERENAEAKVRRLRDDLAQANRLSILGQIAAGVAHEINQPVAAIRTYAENAGR 411 Query: 330 WLDRAVPDLEHARTGLRDIIAEGQRAGGIISGLRDLTRNAAPVCERVNLHAVIRHILTLS 389 +L+ E A L I++ +R G I + LR R + + I L+L Sbjct: 412 FLETG--KTEPASGNLTSIVSMTERIGAITNTLRTFARRPGVAASPLPVREAIDGALSLL 469 Query: 390 RSELERREVSLLLSLTPADAFVLGDQVQLQQVMLNLVVNAIEAMSGMPEHARVLSITASS 449 + V+++ L A V+ +++L+Q+++NL+ NA++AM P+ + I + Sbjct: 470 SGRIRDSGVTIVKPLGTASPMVMASRIRLEQILVNLLQNALDAMKDQPDPR--IEIDLAQ 527 Query: 450 CDEQRIEVRVQDSGEGIAPEAMRRVFDAFYTTKDSGMGMGLAICRSIIENHRGRLRVAAA 509 D+ R+ + V+D+G G+ PEA +F F TTK+ G+G+GL I + I + G LR+ Sbjct: 528 RDD-RVLISVRDNGPGLGPEAAGNLFMPFQTTKEKGLGLGLVISQEIAQELGGTLRLDPD 586 Query: 510 QPHGALFSFDLPRV 523 GA F+ DL R+ Sbjct: 587 STRGASFTIDLRRI 600