BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0183.p (418 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO4034_1 [K] COG1609 Transcriptional regulators Ype Yersinia pe... 264 4e-70 ECs4452_1 [K] COG1609 Transcriptional regulators Ecs Escherichia... 258 2e-68 ZxylR_1 [K] COG1609 Transcriptional regulators EcZ Escherichia c... 258 2e-68 xylR_1 [K] COG1609 Transcriptional regulators Eco Escherichia co... 258 2e-68 HI1106_1 [K] COG1609 Transcriptional regulators Hin Haemophilus ... 245 1e-64 STM3662_1 [K] COG1609 Transcriptional regulators Sty Salmonella ... 242 1e-63 STM3662_2 [K] COG2207 AraC-type DNA-binding domain-containing pr... 112 2e-24 YPO4034_2 [K] COG2207 AraC-type DNA-binding domain-containing pr... 110 7e-24 ECs4452_2 [K] COG2207 AraC-type DNA-binding domain-containing pr... 107 4e-23 ZxylR_2 [K] COG2207 AraC-type DNA-binding domain-containing prot... 107 4e-23 >YPO4034_1 [K] COG1609 Transcriptional regulators Ype Yersinia pestis Length = 265 Score = 264 bits (674), Expect = 4e-70, Method: Compositional matrix adjust. Identities = 124/250 (49%), Positives = 168/250 (67%), Gaps = 1/250 (0%) Query: 8 HRIALLFNGNKIFDREIIAGIGEYISSTRASWDLYLEEDFRCRPQGIERWAGHGIIADFD 67 +RI LLFN NK++DR+++ G+GEY+ +++ +WD+++EEDFRCR I+ W G G+IADFD Sbjct: 6 YRITLLFNANKVYDRQVVEGVGEYLQASQCNWDIFIEEDFRCRIDNIKDWLGDGVIADFD 65 Query: 68 DPVTTAALEGVQLPVVAIGGSYADPSQYPANRPYVATDNYKMVKLAYDHLIEAGLQHFAL 127 D L V +P+V +GGSY YP+ Y+ATDN +V A+ HL E GL FA Sbjct: 66 DRQIEQLLANVNVPIVGVGGSYHQSEDYPS-VDYIATDNKALVNAAFMHLKEKGLNRFAF 124 Query: 128 FSLPESDCNRWAQERERIFTDLTGADGIAGHIYRGVGTSAQSWDTAVEQQIAWVRSLPKP 187 + LP S RWAQERE F L A+ G +Y+G+ T+ +W A + WV++LP Sbjct: 125 YGLPASCGMRWAQEREYAFRQLVSAEQYQGVVYQGMATAPDNWQYAQNRLADWVQTLPHQ 184 Query: 188 VGIIAVTDARARQLLQACLFAGIAVPEQVALIGIDNDPLARVLTRIPLSSVIQGSVEMGR 247 GIIAVTDARAR LLQ C IAVPE++++IGIDN+ L R L+R+ LSSV+QG+ +MG Sbjct: 185 TGIIAVTDARARHLLQVCEHLDIAVPEKLSVIGIDNEELTRYLSRVALSSVVQGTRQMGY 244 Query: 248 TAAHLLHQML 257 AA LLHQ L Sbjct: 245 RAAKLLHQRL 254 >ECs4452_1 [K] COG1609 Transcriptional regulators Ecs Escherichia coli O157:H7 Length = 265 Score = 258 bits (659), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 123/261 (47%), Positives = 170/261 (65%), Gaps = 1/261 (0%) Query: 8 HRIALLFNGNKIFDREIIAGIGEYISSTRASWDLYLEEDFRCRPQGIERWAGHGIIADFD 67 HRI LLFN NK +DR+++ G+GEY+ ++++ WD+++EEDFR R I+ W G G+IADFD Sbjct: 6 HRITLLFNANKAYDRQVVEGVGEYLQASQSEWDIFIEEDFRARIDKIKDWLGDGVIADFD 65 Query: 68 DPVTTAALEGVQLPVVAIGGSYADPSQYPANRPYVATDNYKMVKLAYDHLIEAGLQHFAL 127 D AL V +P+V +GGSY YP Y+ATDNY +V+ A+ HL E G+ FA Sbjct: 66 DKQIEQALADVDVPIVGVGGSYHLAESYPPVH-YIATDNYALVESAFLHLKEKGVNRFAF 124 Query: 128 FSLPESDCNRWAQERERIFTDLTGADGIAGHIYRGVGTSAQSWDTAVEQQIAWVRSLPKP 187 + LPES RWA ERE F L + G +Y+G+ T+ ++W A + W+++LP Sbjct: 125 YGLPESSGKRWATEREYAFRQLVAEEKYRGVVYQGLETAPENWQHAQNRLADWLQTLPPQ 184 Query: 188 VGIIAVTDARARQLLQACLFAGIAVPEQVALIGIDNDPLARVLTRIPLSSVIQGSVEMGR 247 GIIAVTDARAR +LQ C I VPE++ +IGIDN+ L R L+R+ LSSV QG+ +MG Sbjct: 185 TGIIAVTDARARHILQVCEHLHIPVPEKLCVIGIDNEELTRYLSRVALSSVAQGARQMGY 244 Query: 248 TAAHLLHQMLHGARFPDTRIM 268 AA LLH++L P RI+ Sbjct: 245 QAAKLLHRLLDKEEMPLQRIL 265 >ZxylR_1 [K] COG1609 Transcriptional regulators EcZ Escherichia coli O157:H7 EDL933 Length = 265 Score = 258 bits (659), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 123/261 (47%), Positives = 170/261 (65%), Gaps = 1/261 (0%) Query: 8 HRIALLFNGNKIFDREIIAGIGEYISSTRASWDLYLEEDFRCRPQGIERWAGHGIIADFD 67 HRI LLFN NK +DR+++ G+GEY+ ++++ WD+++EEDFR R I+ W G G+IADFD Sbjct: 6 HRITLLFNANKAYDRQVVEGVGEYLQASQSEWDIFIEEDFRARIDKIKDWLGDGVIADFD 65 Query: 68 DPVTTAALEGVQLPVVAIGGSYADPSQYPANRPYVATDNYKMVKLAYDHLIEAGLQHFAL 127 D AL V +P+V +GGSY YP Y+ATDNY +V+ A+ HL E G+ FA Sbjct: 66 DKQIEQALADVDVPIVGVGGSYHLAESYPPVH-YIATDNYALVESAFLHLKEKGVNRFAF 124 Query: 128 FSLPESDCNRWAQERERIFTDLTGADGIAGHIYRGVGTSAQSWDTAVEQQIAWVRSLPKP 187 + LPES RWA ERE F L + G +Y+G+ T+ ++W A + W+++LP Sbjct: 125 YGLPESSGKRWATEREYAFRQLVAEEKYRGVVYQGLETAPENWQHAQNRLADWLQTLPPQ 184 Query: 188 VGIIAVTDARARQLLQACLFAGIAVPEQVALIGIDNDPLARVLTRIPLSSVIQGSVEMGR 247 GIIAVTDARAR +LQ C I VPE++ +IGIDN+ L R L+R+ LSSV QG+ +MG Sbjct: 185 TGIIAVTDARARHILQVCEHLHIPVPEKLCVIGIDNEELTRYLSRVALSSVAQGARQMGY 244 Query: 248 TAAHLLHQMLHGARFPDTRIM 268 AA LLH++L P RI+ Sbjct: 245 QAAKLLHRLLDKEEMPLQRIL 265 >xylR_1 [K] COG1609 Transcriptional regulators Eco Escherichia coli K12 Length = 265 Score = 258 bits (659), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 123/261 (47%), Positives = 170/261 (65%), Gaps = 1/261 (0%) Query: 8 HRIALLFNGNKIFDREIIAGIGEYISSTRASWDLYLEEDFRCRPQGIERWAGHGIIADFD 67 HRI LLFN NK +DR+++ G+GEY+ ++++ WD+++EEDFR R I+ W G G+IADFD Sbjct: 6 HRITLLFNANKAYDRQVVEGVGEYLQASQSEWDIFIEEDFRARIDKIKDWLGDGVIADFD 65 Query: 68 DPVTTAALEGVQLPVVAIGGSYADPSQYPANRPYVATDNYKMVKLAYDHLIEAGLQHFAL 127 D AL V +P+V +GGSY YP Y+ATDNY +V+ A+ HL E G+ FA Sbjct: 66 DKQIEQALADVDVPIVGVGGSYHLAESYPPVH-YIATDNYALVESAFLHLKEKGVNRFAF 124 Query: 128 FSLPESDCNRWAQERERIFTDLTGADGIAGHIYRGVGTSAQSWDTAVEQQIAWVRSLPKP 187 + LPES RWA ERE F L + G +Y+G+ T+ ++W A + W+++LP Sbjct: 125 YGLPESSGKRWATEREYAFRQLVAEEKYRGVVYQGLETAPENWQHAQNRLADWLQTLPPQ 184 Query: 188 VGIIAVTDARARQLLQACLFAGIAVPEQVALIGIDNDPLARVLTRIPLSSVIQGSVEMGR 247 GIIAVTDARAR +LQ C I VPE++ +IGIDN+ L R L+R+ LSSV QG+ +MG Sbjct: 185 TGIIAVTDARARHILQVCEHLHIPVPEKLCVIGIDNEELTRYLSRVALSSVAQGARQMGY 244 Query: 248 TAAHLLHQMLHGARFPDTRIM 268 AA LLH++L P RI+ Sbjct: 245 QAAKLLHRLLDKEEMPLQRIL 265 >HI1106_1 [K] COG1609 Transcriptional regulators Hin Haemophilus influenzae Length = 265 Score = 245 bits (625), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 116/261 (44%), Positives = 172/261 (65%), Gaps = 1/261 (0%) Query: 8 HRIALLFNGNKIFDREIIAGIGEYISSTRASWDLYLEEDFRCRPQGIERWAGHGIIADFD 67 ++IALLFN NK++DR+++ GIG+YI +++ WD+++E++F I + + GIIADFD Sbjct: 6 YKIALLFNANKVYDRQVVEGIGQYIQASQCMWDIFVEDEFIYHTDTINQLSIDGIIADFD 65 Query: 68 DPVTTAALEGVQLPVVAIGGSYADPSQYPANRPYVATDNYKMVKLAYDHLIEAGLQHFAL 127 DP T L+ +P +A+GGSY YP + PY+ATDN +V++A HL E GL FA Sbjct: 66 DPKTVELLQHTLIPTIAVGGSYKQADFYP-HFPYIATDNMALVEMALSHLQEKGLSQFAF 124 Query: 128 FSLPESDCNRWAQERERIFTDLTGADGIAGHIYRGVGTSAQSWDTAVEQQIAWVRSLPKP 187 + L + W+ ER F +L + ++Y GV AQ+W ++ I W++SLP Sbjct: 125 YGLQVNTHKHWSIERRDAFVELMEKNHYPIYLYEGVQVHAQNWLEEQQKLIVWLKSLPSH 184 Query: 188 VGIIAVTDARARQLLQACLFAGIAVPEQVALIGIDNDPLARVLTRIPLSSVIQGSVEMGR 247 GIIAVTDARAR LLQAC ++ IAVPE++ ++GIDN+ L + L+R+ LSSV QG+ E+G Sbjct: 185 TGIIAVTDARARHLLQACEYSKIAVPEELCVVGIDNEELIQYLSRMSLSSVEQGTREIGY 244 Query: 248 TAAHLLHQMLHGARFPDTRIM 268 AA LLH++L+G + T I+ Sbjct: 245 QAAKLLHKLLNGQKVSHTPIL 265 >STM3662_1 [K] COG1609 Transcriptional regulators Sty Salmonella typhimurium LT2 Length = 265 Score = 242 bits (617), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 120/261 (45%), Positives = 169/261 (64%), Gaps = 1/261 (0%) Query: 8 HRIALLFNGNKIFDREIIAGIGEYISSTRASWDLYLEEDFRCRPQGIERWAGHGIIADFD 67 HRI LLFN NK +DR+++ G+GEY+ ++++ WD+++EEDFR R I+ W G G+IAD+D Sbjct: 6 HRITLLFNANKAYDRQVVEGVGEYLQASQSEWDIFIEEDFRARIDNIKEWLGDGVIADYD 65 Query: 68 DPVTTAALEGVQLPVVAIGGSYADPSQYPANRPYVATDNYKMVKLAYDHLIEAGLQHFAL 127 D L V +P+V +GGSY YPA Y+ATDN+ +V+ A+ HL E G+ FA Sbjct: 66 DDDIAQLLADVDVPIVGVGGSYHLAENYPAVH-YIATDNHALVESAFLHLKEKGVNRFAF 124 Query: 128 FSLPESDCNRWAQERERIFTDLTGADGIAGHIYRGVGTSAQSWDTAVEQQIAWVRSLPKP 187 + LP S WA ERE F L + G +Y+G+ T+ ++W A + W+++LP Sbjct: 125 YGLPNSSRKHWAAEREYAFRQLVAEEKYRGVVYQGLETAPENWQHAQNRLADWLQTLPPQ 184 Query: 188 VGIIAVTDARARQLLQACLFAGIAVPEQVALIGIDNDPLARVLTRIPLSSVIQGSVEMGR 247 GIIAVTDARAR +LQAC I VPE++ +IGIDN+ L R L+R+ LSSV QG+ +MG Sbjct: 185 TGIIAVTDARARHVLQACEHLHIPVPEKLCVIGIDNEELTRYLSRVALSSVAQGARQMGY 244 Query: 248 TAAHLLHQMLHGARFPDTRIM 268 AA LLH++L P RI+ Sbjct: 245 QAAKLLHRLLAREEMPLQRIL 265 >STM3662_2 [K] COG2207 AraC-type DNA-binding domain-containing proteins Sty Salmonella typhimurium LT2 Length = 127 Score = 112 bits (279), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 56/126 (44%), Positives = 81/126 (64%) Query: 269 VPPVGINVLASSRHEVRNHPHVMQALHFIRQYACQGIKTDQVADYVGISRSSLEWYFRRE 328 VPPV + S+ + P V+QA+HFIR +AC+GIK +QV D VGISRS+LE F+ E Sbjct: 1 VPPVRVIARRSTDYRSLTDPAVIQAMHFIRNHACKGIKVEQVLDAVGISRSNLEKRFKEE 60 Query: 329 LGRSVHDEILRFKLDAAKRLLEQAGSHAAEIAVSCGFTSVQYMHAVFKRELGCTPREYQE 388 +G ++H I KL+ A+ LL EI+ CG+ S+QY ++VFK+E TP+EY++ Sbjct: 61 VGETIHALIHAEKLEKARSLLISTTLAINEISQMCGYPSLQYFYSVFKKEYVTTPKEYRD 120 Query: 389 QFAAGL 394 Q + L Sbjct: 121 QHSEAL 126 >YPO4034_2 [K] COG2207 AraC-type DNA-binding domain-containing proteins Ype Yersinia pestis Length = 132 Score = 110 bits (275), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 53/126 (42%), Positives = 82/126 (65%) Query: 266 RIMVPPVGINVLASSRHEVRNHPHVMQALHFIRQYACQGIKTDQVADYVGISRSSLEWYF 325 RI+VPPV + S+ P V+QA+H+IR +AC+GIK +QV D VG+SRS+LE F Sbjct: 3 RILVPPVKVMARRSTDFRSLRDPAVIQAMHYIRHHACKGIKVEQVLDAVGMSRSNLEKRF 62 Query: 326 RRELGRSVHDEILRFKLDAAKRLLEQAGSHAAEIAVSCGFTSVQYMHAVFKRELGCTPRE 385 + E+G+++H I KLD A+ LL EI+ CG+ S+QY ++VFK+ TP+E Sbjct: 63 KDEVGQTIHGVIHEEKLDRARNLLAATSLPINEISQMCGYPSLQYFYSVFKKGYSITPKE 122 Query: 386 YQEQFA 391 +++++ Sbjct: 123 HRDKYG 128 >ECs4452_2 [K] COG2207 AraC-type DNA-binding domain-containing proteins Ecs Escherichia coli O157:H7 Length = 127 Score = 107 bits (268), Expect = 4e-23, Method: Composition-based stats. Identities = 53/120 (44%), Positives = 77/120 (64%) Query: 269 VPPVGINVLASSRHEVRNHPHVMQALHFIRQYACQGIKTDQVADYVGISRSSLEWYFRRE 328 VPPV + S+ + P V+QA+H+IR +AC+GIK DQV D VGISRS+LE F+ E Sbjct: 1 VPPVRVIERRSTDYRSLTDPAVIQAMHYIRNHACKGIKVDQVLDAVGISRSNLEKRFKEE 60 Query: 329 LGRSVHDEILRFKLDAAKRLLEQAGSHAAEIAVSCGFTSVQYMHAVFKRELGCTPREYQE 388 +G ++H I KL+ A+ LL EI+ CG+ S+QY ++VFK+ TP+EY++ Sbjct: 61 VGETIHAMIHAEKLEKARSLLISTTLSINEISQMCGYPSLQYFYSVFKKAYDTTPKEYRD 120 >ZxylR_2 [K] COG2207 AraC-type DNA-binding domain-containing proteins EcZ Escherichia coli O157:H7 EDL933 Length = 127 Score = 107 bits (268), Expect = 4e-23, Method: Composition-based stats. Identities = 53/120 (44%), Positives = 77/120 (64%) Query: 269 VPPVGINVLASSRHEVRNHPHVMQALHFIRQYACQGIKTDQVADYVGISRSSLEWYFRRE 328 VPPV + S+ + P V+QA+H+IR +AC+GIK DQV D VGISRS+LE F+ E Sbjct: 1 VPPVRVIERRSTDYRSLTDPAVIQAMHYIRNHACKGIKVDQVLDAVGISRSNLEKRFKEE 60 Query: 329 LGRSVHDEILRFKLDAAKRLLEQAGSHAAEIAVSCGFTSVQYMHAVFKRELGCTPREYQE 388 +G ++H I KL+ A+ LL EI+ CG+ S+QY ++VFK+ TP+EY++ Sbjct: 61 VGETIHAMIHAEKLEKARSLLISTTLSINEISQMCGYPSLQYFYSVFKKAYDTTPKEYRD 120