BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0150.p (249 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGpA300 [IQR] COG1028 Dehydrogenases with different specificitie... 314 1e-85 msl7784m [IQR] COG1028 Dehydrogenases with different specificiti... 304 2e-82 mlr5280 [IQR] COG1028 Dehydrogenases with different specificitie... 282 4e-76 BS_ykvO [IQR] COG1028 Dehydrogenases with different specificitie... 268 1e-71 mlr5278 [IQR] COG1028 Dehydrogenases with different specificitie... 232 7e-61 SMb20871 [IQR] COG1028 Dehydrogenases with different specificiti... 217 2e-56 AGc2317 [IQR] COG1028 Dehydrogenases with different specificitie... 214 2e-55 AGpA564 [IQR] COG1028 Dehydrogenases with different specificitie... 197 2e-50 AGpA642 [IQR] COG1028 Dehydrogenases with different specificitie... 194 1e-49 SMa2165 [IQR] COG1028 Dehydrogenases with different specificitie... 167 2e-41 >AGpA300 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 251 Score = 314 bits (805), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 162/251 (64%), Positives = 188/251 (74%), Gaps = 2/251 (0%) Query: 1 MNKQLNGKIALVTGGTSGIGLATAQELAAQGAQVFITGRRQAELDAAVASIGAAATGIRA 60 M +L KIA+VTG TSGIGLATA+ A +GA+V+ITGRR+ LD AVA IG A G++A Sbjct: 1 MTNRLQNKIAVVTGATSGIGLATAKLFAVEGARVYITGRRKDALDKAVAEIGHGAVGVQA 60 Query: 61 DASVLPDLDTVYAQIAKSAGRLDILFANAGGGDMMPLGAITEEHFDRIFGTNVRGVLFTV 120 D++ +LD ++AQ+ GRLD L NAGGG M+PLG ITEE D FG NV+ V+FTV Sbjct: 61 DSASNENLDKLFAQVKAEQGRLDALVVNAGGGSMLPLGQITEEQIDHTFGRNVKAVIFTV 120 Query: 121 QKALPLLVDGASVILTSSTTSVLGTANFSVYSASKAAVRNFARSWALDLKDRAIRVNVVS 180 QKALPL+ GAS++LT ST GTA FSVYSASKAAVRN ARSWALDLK IRVNVVS Sbjct: 121 QKALPLMGKGASIVLTGSTAGTEGTAAFSVYSASKAAVRNLARSWALDLKGTGIRVNVVS 180 Query: 181 PGPIRTPGLGELVPDDA--RQGLFDYLASQVPLGRLGEPQEIGKAVAFLASDAASFVNGI 238 PG RTPGL EL DD +QGL DYLAS++PLGR+GE +EI KA FLASD ASFVNG Sbjct: 181 PGATRTPGLVELAGDDKEQQQGLLDYLASRIPLGRVGESEEIAKATLFLASDDASFVNGA 240 Query: 239 ELFVDGGMAQV 249 ELF DGG AQV Sbjct: 241 ELFADGGQAQV 251 >msl7784m [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 251 Score = 304 bits (778), Expect = 2e-82, Method: Compositional matrix adjust. Identities = 162/251 (64%), Positives = 192/251 (76%), Gaps = 2/251 (0%) Query: 1 MNKQLNGKIALVTGGTSGIGLATAQELAAQGAQVFITGRRQAELDAAVASIGAAATGIRA 60 M +L GKIA+VTGG+SGIGL A+ AA+GA V+ITGRRQAE+D AVA+IG ATGI+A Sbjct: 1 MTNKLEGKIAVVTGGSSGIGLGIAKRFAAEGAHVYITGRRQAEIDKAVAAIGKHATGIQA 60 Query: 61 DASVLPDLDTVYAQIAKSAGRLDILFANAGGGDMMPLGAITEEHFDRIFGTNVRGVLFTV 120 D++ DLD + ++ +GR+D+L NAGGG M+PLG ITE+HFD F NV VLFTV Sbjct: 61 DSTSFTDLDRLTRRVKARSGRIDVLSVNAGGGSMLPLGQITEQHFDETFDRNVXAVLFTV 120 Query: 121 QKALPLLVDGASVILTSSTTSVLGTANFSVYSASKAAVRNFARSWALDLKDRAIRVNVVS 180 QKAL LL DGASVILT ST G A FSVY ASKAA+RNFARSW +DLK+R IRVN++S Sbjct: 121 QKALTLLADGASVILTGSTAGSTGAAAFSVYGASKAALRNFARSWIIDLKERQIRVNILS 180 Query: 181 PGPIRTPGLGELVPDDARQ--GLFDYLASQVPLGRLGEPQEIGKAVAFLASDAASFVNGI 238 PGP RT GL EL +A Q GL D+LA+QVP+GRLG+P EIGKA FLASD +SFV G Sbjct: 181 PGPTRTTGLAELAGPEAEQQKGLLDFLATQVPMGRLGDPDEIGKAAVFLASDDSSFVTGA 240 Query: 239 ELFVDGGMAQV 249 ELFVDGG AQV Sbjct: 241 ELFVDGGTAQV 251 >mlr5280 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 250 Score = 282 bits (722), Expect = 4e-76, Method: Compositional matrix adjust. Identities = 142/250 (56%), Positives = 179/250 (71%), Gaps = 4/250 (1%) Query: 3 KQLNGKIALVTGGTSGIGLATAQELAAQGAQVFITGRRQAELDAAVASIGAAATGIRADA 62 K+L GKIA++TGG+SGIGLATA+ +GA V ITGRR+ EL A A I T + D Sbjct: 2 KKLEGKIAVITGGSSGIGLATAKRFVEEGAHVVITGRREKELKEAAAFIMRNVTTVVGDV 61 Query: 63 SVLPDLDTVYAQIAKSAGRLDILFANAGGGDMMPLGAITEEHFDRIFGTNVRGVLFTVQK 122 S+L DLD +YA + + G +D+LFANAG G + PL A TE HFD+ F NV+G+ FTVQK Sbjct: 62 SLLEDLDRLYAVVKEKHGHIDVLFANAGAGTIAPLAAATEAHFDQTFDVNVKGLFFTVQK 121 Query: 123 ALPLLVDGASVILTSSTTSVLGTANFSVYSASKAAVRNFARSWALDLKDRAIRVNVVSPG 182 ALPL DG S+IL SS ++VLG FS Y+ASKAAVRNF+R+W L+LKDR IRVN +SPG Sbjct: 122 ALPLFKDGGSIILNSSVSNVLGLPGFSTYAASKAAVRNFSRAWTLELKDRKIRVNTMSPG 181 Query: 183 PIRTPGLGE---LVPDDARQGLFDYLASQVPLGRLGEPQEIGKAVAFLASDAASFVNGIE 239 I TP L L P+ A Q + + ASQ+P+GR G+P+EI AV FLASD +S+V G++ Sbjct: 182 AIETPALETTTGLTPEQAEQAVAQF-ASQIPMGRRGKPEEIAAAVTFLASDDSSYVTGVD 240 Query: 240 LFVDGGMAQV 249 L VDGGMAQV Sbjct: 241 LAVDGGMAQV 250 >BS_ykvO [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Bsu Bacillus subtilis Length = 248 Score = 268 bits (684), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 141/247 (57%), Positives = 173/247 (70%), Gaps = 2/247 (0%) Query: 4 QLNGKIALVTGGTSGIGLATAQELAAQGAQVFITGRRQAELDAAVASIGAAATGIRADAS 63 + GKIALVTGGTSGIGLATAQ+ +GA V+ITGRRQ ELD AV IG TG++ D S Sbjct: 3 KFEGKIALVTGGTSGIGLATAQKFVNEGAYVYITGRRQNELDKAVNQIGKNVTGVQGDIS 62 Query: 64 VLPDLDTVYAQIAKSAGRLDILFANAGGGDMMPLGAITEEHFDRIFGTNVRGVLFTVQKA 123 L DLD +Y I + G+LDILFANAG G+ +PLG ITEE DR F NV+G +FTVQKA Sbjct: 63 KLEDLDKLYDIIKQEKGKLDILFANAGIGNFLPLGEITEEQVDRTFDINVKGTIFTVQKA 122 Query: 124 LPLLVDG-ASVILTSSTTSVLGTANFSVYSASKAAVRNFARSWALDLKDRAIRVNVVSPG 182 L L D S+I+T ST +G FSVY ASKAA+R R+W LDLK IRVNVVSPG Sbjct: 123 LSLFPDKVGSIIVTGSTAGSIGNPAFSVYGASKAALRALVRNWILDLKGTEIRVNVVSPG 182 Query: 183 PIRTPGLGELVPDDARQGLFDYLASQVPLGRLGEPQEIGKAVAFLASDAASFVNGIELFV 242 I TP EL DA + + + + VP G++G P+E+ AV+FLASD +S++ G+ELFV Sbjct: 183 GILTPAYDELF-GDALEEVLENSRNTVPAGKVGTPEEVANAVSFLASDESSYLTGVELFV 241 Query: 243 DGGMAQV 249 DGG+AQV Sbjct: 242 DGGLAQV 248 >mlr5278 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 244 Score = 232 bits (591), Expect = 7e-61, Method: Compositional matrix adjust. Identities = 125/246 (50%), Positives = 159/246 (64%), Gaps = 4/246 (1%) Query: 4 QLNGKIALVTGGTSGIGLATAQELAAQGAQVFITGRRQAELDAAVASIGAAATGIRADAS 63 +LNGK A++TGG +GIG A A +GA VFI GRRQ LDAAVA +GA A ++ S Sbjct: 3 RLNGKTAVITGGATGIGRAAATRFIEEGAFVFIYGRRQEALDAAVADLGANARAVKGSVS 62 Query: 64 VLPDLDTVYAQIAKSAGRLDILFANAGGGDMMPLGAITEEHFDRIFGTNVRGVLFTVQKA 123 L DLD +YA + G LDI+FANAG G +PLG IT EH D F TNV+G +FTVQ+A Sbjct: 63 DLADLDRLYAAVKAERGTLDIVFANAGAGGPLPLGQITAEHIDETFDTNVKGTIFTVQQA 122 Query: 124 LPLLVDGASVILTSSTTSVLGTANFSVYSASKAAVRNFARSWALDLKDRAIRVNVVSPGP 183 LPL+ G S+ILT S+ G F+ YSASKAAVRN AR+WA DLK IRVNV+SPG Sbjct: 123 LPLMGPGGSIILTGSSAGTTGAPGFTAYSASKAAVRNLARTWAEDLKGTGIRVNVLSPGA 182 Query: 184 IRTPGLGELVPDDARQGLFDYLASQVPLGRLGEPQEIGKAVAFLASDAASFVNGIELFVD 243 T E + ++ ++ + PL R+ +P EIG AFLAS +SF+ E+ VD Sbjct: 183 TATELAKEALGEEGQKA----YGAMTPLQRMADPAEIGAVAAFLASSDSSFMTASEVAVD 238 Query: 244 GGMAQV 249 GG+AQ+ Sbjct: 239 GGLAQL 244 >SMb20871 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Sme Sinorhizobium meliloti Length = 249 Score = 217 bits (552), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 118/245 (48%), Positives = 155/245 (63%), Gaps = 1/245 (0%) Query: 3 KQLNGKIALVTGGTSGIGLATAQELAAQGAQVFITGRRQAELDAAVASIGAAATGIRADA 62 L K+A++TGG SGIG ATA+ A +GA+V ITGRR+ +D AV IG +A G DA Sbjct: 2 HHLKDKVAVITGGNSGIGKATARLFAEEGAKVIITGRRRDVVDRAVQEIGPSAIGFVGDA 61 Query: 63 SVLPDLDTVYAQIAKSAGRLDILFANAGGGDMMPLGAITEEHFDRIFGTNVRGVLFTVQK 122 + L D + + G LDI ANA ++ P +T E +DR F TN RGV F VQ Sbjct: 62 ADLGDHRRLADAVKSRFGGLDIYMANAAVINLTPSAEVTPEDYDRHFATNTRGVFFGVQT 121 Query: 123 ALPLLVDGASVILTSSTTSVLGTANFSVYSASKAAVRNFARSWALDLKDRAIRVNVVSPG 182 PL+ DG S+I+TSS + + +VY+ SKAA FA++WAL+ K R IRVN++SPG Sbjct: 122 IAPLIRDGGSIIVTSSLAATKILPDHTVYAGSKAATAAFAKNWALEFKSRRIRVNILSPG 181 Query: 183 PIRTPGLGEL-VPDDARQGLFDYLASQVPLGRLGEPQEIGKAVAFLASDAASFVNGIELF 241 P+ T L +L V + R D +AS +P GRLG P+E+ +A FLASDA SFVNG+EL Sbjct: 182 PVETEILAKLGVSEAERPAFEDRMASLIPAGRLGRPEELARAALFLASDAGSFVNGVELH 241 Query: 242 VDGGM 246 VDGGM Sbjct: 242 VDGGM 246 >AGc2317 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 292 Score = 214 bits (545), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 117/252 (46%), Positives = 161/252 (63%), Gaps = 3/252 (1%) Query: 1 MNKQLNGKIALVTGGTSGIGLATAQELAAQGAQ-VFITGRRQAELDAAVASIGAAATGIR 59 M+ +G++ +VTGG++GIG + A+ GA V++TGR A LDAAVA +G A G Sbjct: 41 MSGIFSGQVVVVTGGSTGIGFSVAKLFLEGGASTVYVTGRNSANLDAAVAKLGKGAIGFV 100 Query: 60 ADASVLPDLDTVYAQIAKSAGRLDILFANAGGGDMMPLGAITEEHFDRIFGTNVRGVLFT 119 +D + L DL+ + +++ ++D+L ANAG + LG E +DRIF NV+GV +T Sbjct: 101 SDVAKLSDLEQLKSRLEADGRKVDVLVANAGIAENNDLGETHEALYDRIFDINVKGVFYT 160 Query: 120 VQKALPLLVDGASVILTSSTTSVLGTANFSVYSASKAAVRNFARSWALDLKDRAIRVNVV 179 VQ LP+L DG S++LT S G S Y+ASKAAVR+FARS+A DLK R IRVN V Sbjct: 161 VQTLLPVLRDGGSIVLTGSIVGNKGMERLSAYNASKAAVRSFARSFANDLKGRGIRVNTV 220 Query: 180 SPGPIRTPGL--GELVPDDARQGLFDYLASQVPLGRLGEPQEIGKAVAFLASDAASFVNG 237 SPG RTP + G + D+ G YL P+GR+ +P EI +AV FLAS AS++ G Sbjct: 221 SPGVTRTPIMENGLKMDDEKIAGFKAYLKDAAPIGRMADPDEIAEAVLFLASSKASYITG 280 Query: 238 IELFVDGGMAQV 249 +EL VDGG+AQ+ Sbjct: 281 VELSVDGGLAQI 292 >AGpA564 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 286 Score = 197 bits (500), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 110/244 (45%), Positives = 158/244 (64%), Gaps = 1/244 (0%) Query: 4 QLNGKIALVTGGTSGIGLATAQELAAQGAQVFITGRRQAELDAAVASIGAAATGIRADAS 63 +L K AL+TGGTSGIGL TA++ ++GA+V +TG LDAA +G +A I+ADA+ Sbjct: 40 RLKSKRALITGGTSGIGLETARQFISEGARVAVTGTNPETLDAARRELGPSALVIKADAA 99 Query: 64 VLPDLDTVYAQIAKSAGRLDILFANAGGGDMMPLGAITEEHFDRIFGTNVRGVLFTVQKA 123 + V I ++ G LD++F NAG + PL A E+ FDR+F NV+G F +Q Sbjct: 100 DVDGQKVVAETIREAFGGLDVVFINAGVALLKPLEAWDEKGFDRVFNINVKGPYFLLQAL 159 Query: 124 LPLLVDGASVILTSSTTSVLGTANFSVYSASKAAVRNFARSWALDLKDRAIRVNVVSPGP 183 LP+L + AS++L +S + +G N SVY+ASKAA+++F R+ + +L R IR+N VSPGP Sbjct: 160 LPILANPASIVLNTSVNAHIGMPNSSVYAASKAALQSFIRTLSGELIARGIRLNAVSPGP 219 Query: 184 IRTPGLGEL-VPDDARQGLFDYLASQVPLGRLGEPQEIGKAVAFLASDAASFVNGIELFV 242 I TP G+L + + + + + + VP GR GEP EI KAV FLASD A++ G E+ + Sbjct: 220 ISTPLYGKLGFTETDLKNVAESIQNLVPAGRFGEPSEIAKAVVFLASDEAAYTVGSEIMI 279 Query: 243 DGGM 246 DGGM Sbjct: 280 DGGM 283 >AGpA642 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 248 Score = 194 bits (493), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 108/246 (43%), Positives = 153/246 (62%), Gaps = 5/246 (2%) Query: 4 QLNGKIALVTGGTSGIGLATAQELAAQGAQVFITGRRQAELDAAVASIGAAATGIRADAS 63 Q++ K+ALV GG GIGLA A+ L+ +GA+VFIT RR + + A +IG A GI ADA+ Sbjct: 8 QMSSKVALVVGGAKGIGLAIAERLSEEGAKVFITSRRSEDAEKAATAIGHGAIGIAADAA 67 Query: 64 VLPDLDTVYAQIAKSAGRLDILFANAGGGDMMPLGAITEEHFDRIFGTNVRGVLFTVQKA 123 + D+ ++ K+ GR+D L NAG + + IT EHFDR F NVRG++F Q A Sbjct: 68 IPEDMVATVEKVRKAHGRIDALVLNAGLSEPAQIAEITPEHFDRHFDVNVRGMVFGFQAA 127 Query: 124 LPLLVDGASVILTSSTTSVLGTANFSVYSASKAAVRNFARSWALDLKDRAIRVNVVSPGP 183 LP + +G SV+L S G A++ Y+A+KAAVR++AR+W +L IRVNVV+PGP Sbjct: 128 LPAMTEGGSVVLVGSIADSGGYASYGTYAATKAAVRSYARTWTAELASVGIRVNVVAPGP 187 Query: 184 IRTPGLGELVPDDARQGLFDYLASQVPLGRLGEPQEIGKAVAFLASDAASFVNGIELFVD 243 T + + PD + + + +P+GR+ P E+ A FL SD AS++ G EL VD Sbjct: 188 TDTEMMAAVQPD-----MRAAIVAPIPMGRMARPSEVAAAALFLLSDDASYIAGAELCVD 242 Query: 244 GGMAQV 249 GG+ QV Sbjct: 243 GGLRQV 248 >SMa2165 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Sme Sinorhizobium meliloti Length = 246 Score = 167 bits (423), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 99/243 (40%), Positives = 141/243 (58%), Gaps = 2/243 (0%) Query: 4 QLNGKIALVTGGTSGIGLATAQELAAQGAQVFITGRRQAELDAAVASIGAAATGIRADAS 63 + GK L+TGGTSGIGLA + + A+G V +TG + L+A G A +R + + Sbjct: 3 RFTGKNVLITGGTSGIGLAGGRRIIAEGGMVILTGMNEDRLEATRKEFGDKAVVVR-NDA 61 Query: 64 VLPDLDTVYAQIAKSAGRLDILFANAGGGDMMPLGAITEEHFDRIFGTNVRGVLFTVQKA 123 P ++I KSAG +D L+ NA + P I FDR+ TNVRG + + K Sbjct: 62 ADPAASADLSEIVKSAGGIDGLWLNAAFAALGPPEEIHAWDFDRMMATNVRGPMLQLAKL 121 Query: 124 LPLLVDGASVILTSSTTSVLGTANFSVYSASKAAVRNFARSWALDLKDRAIRVNVVSPGP 183 PLL G S++LTSS+++ G + S+Y+A+K AV +RSWA + R IRVNV+ PGP Sbjct: 122 SPLLRPGTSIVLTSSSSTYEGASATSLYAATKGAVLAMSRSWASAMAPRGIRVNVLVPGP 181 Query: 184 IRTPGLGELVPDDARQGLFDYLASQVPLGRLGEPQEIGKAVAFLASDAASFVNGIELFVD 243 I + L +PD+AR G ++ +QVPLGR+G E FL SD +S+V G + VD Sbjct: 182 IES-NLRSFLPDEARHGFERFVLNQVPLGRVGTADEAAAVALFLLSDDSSYVTGSQYAVD 240 Query: 244 GGM 246 GG+ Sbjct: 241 GGL 243